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Conserved domains on  [gi|497531954|ref|WP_009846152|]
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MULTISPECIES: carbohydrate ABC transporter permease [Vibrio]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 10003067)

carbohydrate ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of carbohydrate substrates including trehalose, lactose, arabinose, and maltodextrin

Gene Ontology:  GO:0042626|GO:0140359|GO:0008643|GO:0055085
PubMed:  25750732|24638992|30626703
TCDB:  3.A.1.1.-

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
11-324 1.05e-92

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 277.79  E-value: 1.05e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  11 PADKSLFSRLNLKALTPYGFLLPFLIIFSVFGIFPLLFSVYLSFHEWNPVRGmdAMEFVGFENYHIALTDPWLWRSLKNT 90
Cdd:COG1175    4 TTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGP--PPEFVGLDNYARLFTDPRFWNALGNT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  91 LWLAITSGVAQHLVAIPVAYMLVSMGdRMRHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQTLMALadstlfgwaf 170
Cdd:COG1175   82 LLFTVVSVPLQLVLGLLLALLLNRKL-RGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGAL---------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 171 awvnDFQPIRWLDDATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAI 250
Cdd:COG1175  151 ----GLEPINWLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVL 226

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497531954 251 TMTIIGNLQMFEEPFVLTRgtGGTGQSGLTISMYLYKVGWEWLEMGTASAISWLLFALIATCTLVQFLLFGKKG 324
Cdd:COG1175  227 VLSTIGALQVFDLVYVLTG--GGPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRRE 298
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
11-324 1.05e-92

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 277.79  E-value: 1.05e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  11 PADKSLFSRLNLKALTPYGFLLPFLIIFSVFGIFPLLFSVYLSFHEWNPVRGmdAMEFVGFENYHIALTDPWLWRSLKNT 90
Cdd:COG1175    4 TTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGP--PPEFVGLDNYARLFTDPRFWNALGNT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  91 LWLAITSGVAQHLVAIPVAYMLVSMGdRMRHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQTLMALadstlfgwaf 170
Cdd:COG1175   82 LLFTVVSVPLQLVLGLLLALLLNRKL-RGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGAL---------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 171 awvnDFQPIRWLDDATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAI 250
Cdd:COG1175  151 ----GLEPINWLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVL 226

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497531954 251 TMTIIGNLQMFEEPFVLTRgtGGTGQSGLTISMYLYKVGWEWLEMGTASAISWLLFALIATCTLVQFLLFGKKG 324
Cdd:COG1175  227 VLSTIGALQVFDLVYVLTG--GGPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRRE 298
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
30-317 4.28e-17

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 79.87  E-value: 4.28e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  30 FLLPFLIIFSVFGIFPLLFSVYLSFHEWNPVrGMDAmEFVGFENYHIALTDPW----LWRSLKNTLWLAITSGVAQHLVA 105
Cdd:PRK10561   2 LVAPQLIITVIFFIWPAGEALWYSLQSVDPF-GFSS-QFVGLDNFVALFHDSYyldsFWTTIKFSTLVTVSGLLVSLFFA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 106 IPVAYMLvsmgdRMRHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQTLMaladstlfGWAFAWvndfqpirwlDDA 185
Cdd:PRK10561  80 ALVDYVV-----RGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLA--------EFGYDW----------NHA 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 186 TMVKPSIAIMVF---WKYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAITMTIIgnLQMFE 262
Cdd:PRK10561 137 QNSGQAMFLVVFasvWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLV--YAFFD 214

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 497531954 263 EPFVLTRGT-GGTGQSGLTISMYLYKVGWEWLEMGTASAISWLLFALIATCTLVQF 317
Cdd:PRK10561 215 TFPVIDAATsGGPVQATTTLIYKIYREGFTGLDLSSSAAQSVVLMFLVIVLTVVQF 270
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 87-309 2.10e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 56.13  E-value: 2.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  87 LKNTLWLAITSGVAQHLVAIPVAYMLVSMGDRMRHWLTSAYFLPFITSTVAASLIFFnmyspnsgiinqtlmaladsTLF 166
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLV--------------------LLF 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 167 GWAFAWVNDFQPIRWlddatmvkpSIAIMVFWkYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFI 246
Cdd:cd06261   61 GVLLGWGILPGLGLP---------ALILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPI 130

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497531954 247 FFAITMTIIGNLQMFEEPFVLTRGTGGTGQSGLTISMYLYKVGWewleMGTASAISWLLFALI 309
Cdd:cd06261  131 LTGLVLAFARALGEFALVSFLGGGEAPGPGTGLLLIFAILFPGD----LGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 170-258 8.01e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 51.53  E-value: 8.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  170 FAWVNDFQPIRWLDDATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFA 249
Cdd:pfam00528  33 FVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTG 112


                  ....*....
gi 497531954  250 ITMTIIGNL 258
Cdd:pfam00528 113 LALAFGGAL 121
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 29-310 1.31e-05

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 46.60  E-value: 1.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954   29 GFLLPFLIIFSVFGIFPLLFSVYLSFHEwnpvrgmDAMEFVGFENYHIALTDPWLWRSLKNTLWLAITSGVaqhlVAIPV 108
Cdd:TIGR03262   5 LLLAGMILALLLFLLLPLLALLTKSVYD-------SDGDFIGLANFAEYFATPGLLQSLGNSLTVSAIVTA----IVVPL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  109 AYmlvsmgdrmrhwlTSAYFLpfiTSTVAASLIFFNMYSpnsgiinqTLMALADSTLFGWAFAWVNDFQPI--RWLDDAT 186
Cdd:TIGR03262  74 AF-------------AFAYAL---TRSRIPGKGAFRLVA--------LLPLLAPSLLPAISLIYLFGNQGLlkGLLGGFS 129

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  187 MV-KPSIAI-MVFWKYTGFNIVLyTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAITMTIIGNLQMFEEP 264
Cdd:TIGR03262 130 IYgFWGIVIgEVFYTFPHALMIL-VTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVP 208

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 497531954  265 FVLtrgtgGTGQSGLTISMYLYKVGWEWLEMGTASAISWLLFALIA 310
Cdd:TIGR03262 209 KVI-----GGDYNVLATDIYKQVIGQQNFPMGAVVGVLLLLPALLA 249
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
11-324 1.05e-92

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 277.79  E-value: 1.05e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  11 PADKSLFSRLNLKALTPYGFLLPFLIIFSVFGIFPLLFSVYLSFHEWNPVRGmdAMEFVGFENYHIALTDPWLWRSLKNT 90
Cdd:COG1175    4 TTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGP--PPEFVGLDNYARLFTDPRFWNALGNT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  91 LWLAITSGVAQHLVAIPVAYMLVSMGdRMRHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQTLMALadstlfgwaf 170
Cdd:COG1175   82 LLFTVVSVPLQLVLGLLLALLLNRKL-RGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGAL---------- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 171 awvnDFQPIRWLDDATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAI 250
Cdd:COG1175  151 ----GLEPINWLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVL 226

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497531954 251 TMTIIGNLQMFEEPFVLTRgtGGTGQSGLTISMYLYKVGWEWLEMGTASAISWLLFALIATCTLVQFLLFGKKG 324
Cdd:COG1175  227 VLSTIGALQVFDLVYVLTG--GGPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRRE 298
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 28-302 2.00e-38

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 138.30  E-value: 2.00e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  28 YGFLLPFLIIFSVFGIFPLlFSVYLSFHEWNPVRGMDAMEFVGFENYHIALTDPWLWRSLKNTLWLAITSGVAQHLVAIP 107
Cdd:COG4209   30 YLMLLPGLIYLLIFSYLPM-YGIVIAFKDYNPFKGIFGSPWVGLKNFKFLFSSPDFWRVLRNTLLISLLKLVFGFPLPII 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 108 VAYMLVSM-GDRMRHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQTLMALadstlfgwafawvnDFQPIRWLDDAT 186
Cdd:COG4209  109 LALLLNELrSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLSPDTGLVNQLLRAL--------------GGEPINFLTEPK 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 187 MVKPSIAIMVFWKYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIffaITMTI--IGNLqM---F 261
Cdd:COG4209  175 YFRPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPTI---VILLIlnIGNI-LnvgF 250

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 497531954 262 EEPFVLtrGTGGTGQSGLTISMYLYKVGWEWLEMGTASAIS 302
Cdd:COG4209  251 EQIYLL--YNPLNYSTSDVIDTYVYRIGLQNGDYSYATAVG 289
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 23-327 4.69e-33

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 123.33  E-value: 4.69e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  23 KALTPYGFLLPFLIIFSVFGIFPLLFSVYLSFHEWNPVRGMDAmEFvGFENYHIALTDPWLWRSLKNTLWLAITSGVAQH 102
Cdd:COG1176    7 RRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVP-GF-TLENYARLFTDPLYLKVLLRTLWIALLTTLICL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 103 LVAIPVAYMLVSMGDRMRHWLTSAYFLPFITSTVAASLIFFNMYSPNsGIINQTLMALadstlfGWAFawvndfQPIRWL 182
Cdd:COG1176   85 LLGYPIAYFLARAPPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRN-GLLNSLLLAL------GLID------EPLRLL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 183 DDATMVkpsIAIMVfWKYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAITMTIIGNLQMFE 262
Cdd:COG1176  152 YTEFAV---VIGLV-YVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFV 227

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497531954 263 EPFVLtrgtGGTgqSGLTISMYLYKVGWEWLEMGTASAISWLLFALIATCTLVQFLLFGKKGLGE 327
Cdd:COG1176  228 TPALL----GGG--KVLMIGNLIYQQFLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRRRRLLG 286
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
27-323 3.90e-22

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 96.77  E-value: 3.90e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  27 PYGFLLPFLIIFSVFGIFPLLFSVYLSFhewnpvrgmdameFVGFENYHIALTDPWLWRSLKNTLWLAITSGVAQHLVAI 106
Cdd:COG1178    9 PRLLLLLLALLLALLVLLPLLALLLRAF-------------TDGLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 107 PVAYmLVSMGD-RMRHWLTSAYFLPFITSTVAASLIFFNMYSPNsGIINQTLMALadstlFGWAFAWVNDFQPIrwldda 185
Cdd:COG1178   76 PLAW-LLARTDfPGRRLLRWLLLLPLALPPYVVALAWIALFGPN-GLLNTLLRAL-----FGLEPPDIYGLGGI------ 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 186 tmvkpsIAIMVFWkYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAITMTIIGNLQMFEEPF 265
Cdd:COG1178  143 ------ILVLVLF-NYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPL 215

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 497531954 266 VLtrgtggtGQSGLTISMYLYKVGWEWLEMGTASAISWLLFALIATCTLVQFLLFGKK 323
Cdd:COG1178  216 VL-------GGGYTTLTTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRRR 266
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
30-317 4.28e-17

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 79.87  E-value: 4.28e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  30 FLLPFLIIFSVFGIFPLLFSVYLSFHEWNPVrGMDAmEFVGFENYHIALTDPW----LWRSLKNTLWLAITSGVAQHLVA 105
Cdd:PRK10561   2 LVAPQLIITVIFFIWPAGEALWYSLQSVDPF-GFSS-QFVGLDNFVALFHDSYyldsFWTTIKFSTLVTVSGLLVSLFFA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 106 IPVAYMLvsmgdRMRHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQTLMaladstlfGWAFAWvndfqpirwlDDA 185
Cdd:PRK10561  80 ALVDYVV-----RGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLA--------EFGYDW----------NHA 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 186 TMVKPSIAIMVF---WKYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAITMTIIgnLQMFE 262
Cdd:PRK10561 137 QNSGQAMFLVVFasvWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLV--YAFFD 214

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 497531954 263 EPFVLTRGT-GGTGQSGLTISMYLYKVGWEWLEMGTASAISWLLFALIATCTLVQF 317
Cdd:PRK10561 215 TFPVIDAATsGGPVQATTTLIYKIYREGFTGLDLSSSAAQSVVLMFLVIVLTVVQF 270
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 34-271 7.10e-16

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 76.29  E-value: 7.10e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  34 FLIIFSVFGIFPLLFSVYLSFHEWNPVRGMDAMEF---VGFENYHIALTDPWLWRSLKNTLWLAITSGVAQHLVAIPVAY 110
Cdd:COG0395   20 LLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLpseFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLAAY 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 111 MLVSMGDRMRHWLT----SAYFLPFITSTVAASLIFFNMyspnsGIINqTLMALAdstLFGWAFAwvndfqpirwlddat 186
Cdd:COG0395  100 ALARFRFRGRKLLFllilATLMIPGQVLLIPLYLLFRQL-----GLLN-TYWGLI---LPYLAFG--------------- 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 187 mvkpsiaimvfwkyTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAITMTIIGNLQMFEEPFV 266
Cdd:COG0395  156 --------------LPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLI 221


                 ....*
gi 497531954 267 LTRGT 271
Cdd:COG0395  222 LLTSP 226
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
34-323 6.18e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 66.34  E-value: 6.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  34 FLIIFSVFGIFPLLFSVYLSFHEWNPvrgmdamEFVGFENYHIALTDPWLWRSLKNTLWLAITSGVAQHLVAIPVAYMLV 113
Cdd:COG1178  294 CLLLVLLGLLLPLLALLLWSLTKALD-------DNLTLDNYRFVLLDPSLLRALLNSLLLALLAALLAVLLALLLAYLVR 366

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 114 SMGDRMRHWLTSAYFLPFITS--TVAASLIFFnMYSPNSGIINQTLMALAdstlfgWAFAwvndfqpIRWLddATMVKPS 191
Cdd:COG1178  367 RRRGRLARLLDRLAMLPYAVPgiVLGLGLLLL-FNRPLPLLLYGTLAILV------LAYV-------VRFL--PFALRSL 430

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 192 IAimvfwkytgfnivlyttGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAITMTiignlqmfeepFVLTRGT 271
Cdd:COG1178  431 EA-----------------ALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLV-----------FVTSMKE 482

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497531954 272 ggtgqsgLTISMYLYKVGWEWL-----------EMGTASAISWLLFALIATCTLVQFLLFGKK 323
Cdd:COG1178  483 -------LSATLLLRPPGFETLavliyqlassgRYGEAAALALLLVLVSLLPVLLLERLLGRR 538
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 30-324 2.93e-11

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 62.82  E-value: 2.93e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  30 FLLPFLIIFSVFGIFPLLFSVYLSFhewNPVRGMdAMEFVGF--ENYHIALTDPWLWRSLKNTLWLAITSGVAQHLVAIP 107
Cdd:COG1177    8 LLRLFLALVLLFLYLPILVLVLYSF---NDSWFL-TFPPEGFtlRWYAELFSDPRLLDALLNSLLIALLSTLLATVLGTP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 108 VAYMLVSMGDRMRHWLTSAYFLPFITSTVA---ASLIFFNMYSPNSGIinqTLMALADSTLfgwafawvndfqpirwldd 184
Cdd:COG1177   84 AALALARYRFRGRRLLLALLLLPLVVPGIVlgvALLLLFSALGLSGGL---WGLILAHVVF------------------- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 185 atmvkpSIAIMVFwkytgfnIVlyTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFI----FFAITMTiignlqm 260
Cdd:COG1177  142 ------TLPFVVL-------VV--LARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGIlagaLLAFTLS------- 199

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 497531954 261 FEEpFVLTRGTGGTGQSGLTISMYLYkvgwewLEMG---TASAISWLLFALIATCTLVQFLLFGKKG 324
Cdd:COG1177  200 FDE-FVITLFLAGPGVTTLPVYIYSM------IRRGispEINALSTLLILLSLLLLLLAERLRRRGE 259
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 34-256 3.61e-10

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 59.78  E-value: 3.61e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  34 FLIIFSVFGIFPLLFSVYLSFhewNPVRGMDAMEF----VGFENYHIALTDPWLWRSLKNTLWLAITSGVAQHLVAIPVA 109
Cdd:COG3833   21 VLIILAIIALFPILWVVSASF---NPGGSLYSSSLipenFTLENYKKLFTETPFLRWFLNSLIVAVVTAIISVFLAALAA 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 110 YMLVSMGDRMRHWLTSAYFL----PFITSTVAASLIFFNMyspnsGIINqTLMALadstlfgwafawvndfqpirwldda 185
Cdd:COG3833   98 YAFSRFRFKGRKAGLLALLLlqmfPAFLALVALYLLLSAL-----GLLN-TLLGL------------------------- 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497531954 186 tmvkpsiaIMVfwkYTG----FNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAITMTIIG 256
Cdd:COG3833  147 --------ILV---YLGgaipFNTWLMKGYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIG 210
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 30-260 7.14e-10

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 58.61  E-value: 7.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  30 FLLPFLIIFSVFGIFPLLFSVYLSFHewnpvrgmdamefVGFENYHIALTDPWLWRSLKNTLWLAITSGVAQHLVAIPVA 109
Cdd:COG0555   12 TLGLTLLYLSLIVLLPLAALVLKAAG-------------LGWAEFWAVLTSPRVLAALKLSLGTALIAALINLVFGLPLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 110 YMLVSMGDRMRHWLTSAYFLPFITSTVAASLIFFNMYSPNsGIINQTLMAladstlFGWAFAwvndFQPIrwlddatmvk 189
Cdd:COG0555   79 WVLVRYRFPGKRLVDALVDLPFALPTAVAGIALLLLFGPN-GWLGQLLAP------LGIKVA----FTPL---------- 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 190 pSIAI-MVFwkyTGFNIVLYT--TGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIF-------------FAITMT 253
Cdd:COG0555  138 -GIVLaQTF---VSLPFVVRTvqPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLtgfalafaralgeFGAVIF 213


                 ....*..
gi 497531954 254 IIGNLQM 260
Cdd:COG0555  214 IAGNLPM 220
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 87-309 2.10e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 56.13  E-value: 2.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  87 LKNTLWLAITSGVAQHLVAIPVAYMLVSMGDRMRHWLTSAYFLPFITSTVAASLIFFnmyspnsgiinqtlmaladsTLF 166
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLV--------------------LLF 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 167 GWAFAWVNDFQPIRWlddatmvkpSIAIMVFWkYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFI 246
Cdd:cd06261   61 GVLLGWGILPGLGLP---------ALILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPI 130

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497531954 247 FFAITMTIIGNLQMFEEPFVLTRGTGGTGQSGLTISMYLYKVGWewleMGTASAISWLLFALI 309
Cdd:cd06261  131 LTGLVLAFARALGEFALVSFLGGGEAPGPGTGLLLIFAILFPGD----LGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 170-258 8.01e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 51.53  E-value: 8.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  170 FAWVNDFQPIRWLDDATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFA 249
Cdd:pfam00528  33 FVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTG 112


                  ....*....
gi 497531954  250 ITMTIIGNL 258
Cdd:pfam00528 113 LALAFGGAL 121
malF PRK10999
maltose ABC transporter permease MalF;
140-316 1.73e-06

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 49.19  E-value: 1.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 140 LIFFNMYSPNSGIINQTLmaladSTLFGWAFAWVNDfqpirwlddATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPKDI 219
Cdd:PRK10999 340 LIFKGLFNQSFGEINMML-----SALFGIKPAWFSD---------PTLAKTMILIVNTWLGYPYMMILCMGLLKAIPDDL 405

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 220 LEAARMDGANAFRRFWNISLP-MIRPFIFFAITmTIIGNLQMFEEPFVLTRG-------TGGTGQSGLTISmYLYKVGWE 291
Cdd:PRK10999 406 YEASAMDGAGPFQNFFKITLPlLIKPLTPLMIA-SFAFNFNNFVLIQLLTNGgpdmigtTTPAGYTDLLVS-YTYRIAFE 483

                        170       180
                 ....*....|....*....|....*...
gi 497531954 292 ---WLEMGTASAISWLLFALIATCTLVQ 316
Cdd:PRK10999 484 gggGQDFGLAAAIATLIFLLVGALAILN 511
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 29-310 1.31e-05

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 46.60  E-value: 1.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954   29 GFLLPFLIIFSVFGIFPLLFSVYLSFHEwnpvrgmDAMEFVGFENYHIALTDPWLWRSLKNTLWLAITSGVaqhlVAIPV 108
Cdd:TIGR03262   5 LLLAGMILALLLFLLLPLLALLTKSVYD-------SDGDFIGLANFAEYFATPGLLQSLGNSLTVSAIVTA----IVVPL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  109 AYmlvsmgdrmrhwlTSAYFLpfiTSTVAASLIFFNMYSpnsgiinqTLMALADSTLFGWAFAWVNDFQPI--RWLDDAT 186
Cdd:TIGR03262  74 AF-------------AFAYAL---TRSRIPGKGAFRLVA--------LLPLLAPSLLPAISLIYLFGNQGLlkGLLGGFS 129

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  187 MV-KPSIAI-MVFWKYTGFNIVLyTTGLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIFFAITMTIIGNLQMFEEP 264
Cdd:TIGR03262 130 IYgFWGIVIgEVFYTFPHALMIL-VTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVP 208

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 497531954  265 FVLtrgtgGTGQSGLTISMYLYKVGWEWLEMGTASAISWLLFALIA 310
Cdd:TIGR03262 209 KVI-----GGDYNVLATDIYKQVIGQQNFPMGAVVGVLLLLPALLA 249
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 71-261 4.53e-05

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 44.29  E-value: 4.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954  71 FENYhIALTDPWLWRSLKNTLWLAITSGVAQHLVAIPVAYMLVSMGDRMRHWLTSAYFLPFITStvaaSLIF---FNMYS 147
Cdd:PRK09497  50 LDNY-TRLLDPLYAEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLLFLLIVPFWTN----SLIRiygLKIFL 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497531954 148 PNSGIINQTLMALAdstlfgwafawVNDfQPIRwlddatMVKPSIAIMVFWKYT--GFNIVLYTTGLMTIPKDILEAARM 225
Cdd:PRK09497 125 STKGYLNEFLLWLG-----------VID-TPIR------IMFTESAVIIGLVYIllPFMVLPLYSSIEKLDKPLLEAARD 186

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 497531954 226 DGANAFRRFWNISLPMIRPFIFFAITMTIIGNLQMF 261
Cdd:PRK09497 187 LGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMF 222
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 192-247 1.72e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 39.36  E-value: 1.72e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 497531954 192 IAIMVFWkytgfnIVLYTT--GLMTIPKDILEAARMDGANAFRRFWNISLPMIRPFIF 247
Cdd:COG0600  132 IFLGAFF------PILLNTaaGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIF 183
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
213-251 1.85e-03

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 39.33  E-value: 1.85e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 497531954 213 MTIPKDILEAARMDGANAFRRFWNISLPMIRPFI--FFAIT 251
Cdd:PRK10973 167 MTLPDELVEAARIDGASPMRFFWDIVLPLSKTNLaaLFVIT 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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