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Conserved domains on  [gi|497731324|ref|WP_010045508|]
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transposase [Gemmata obscuriglobus]

Protein Classification

IS66 family transposase( domain architecture ID 1750062)

IS66 family transposase insertion sequence element encodes a DDE transposase TnpC, and two accessory proteins, TnpA and TnpB.

PubMed:  20079432

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS66 super family cl41296
IS66 family transposase; Members of this protein family are DDE transposases from the IS66 ...
 12-92 4.70e-21

IS66 family transposase; Members of this protein family are DDE transposases from the IS66 family insertion sequences, which typically consist of two accessary genes (TnpA and TnpB) and the third gene encoding the transposase.


The actual alignment was detected with superfamily member NF033517:

Pssm-ID: 468053 [Multi-domain]  Cd Length: 388  Bit Score: 85.71  E-value: 4.70e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497731324  12 TLAKHLWNHFEQWFTFVFDPRVEPTNWKAEQAIRPAVVNRKVWGGNRTAAGAKAQGVLMSVFETCRRRTLSVVDHISQTL 91
Cdd:NF033517 306 KAIRYLLNRWDALLRFLDDGRVPIDNNAAERAIRPVVLGRKNSLFAGSDRGAEAAARIYSLIETAKLNGLNPYAYLRDVL 385


                 .
gi 497731324  92 R 92
Cdd:NF033517 386 T 386
 
Name Accession Description Interval E-value
transpos_IS66 NF033517
IS66 family transposase; Members of this protein family are DDE transposases from the IS66 ...
 12-92 4.70e-21

IS66 family transposase; Members of this protein family are DDE transposases from the IS66 family insertion sequences, which typically consist of two accessary genes (TnpA and TnpB) and the third gene encoding the transposase.


Pssm-ID: 468053 [Multi-domain]  Cd Length: 388  Bit Score: 85.71  E-value: 4.70e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497731324  12 TLAKHLWNHFEQWFTFVFDPRVEPTNWKAEQAIRPAVVNRKVWGGNRTAAGAKAQGVLMSVFETCRRRTLSVVDHISQTL 91
Cdd:NF033517 306 KAIRYLLNRWDALLRFLDDGRVPIDNNAAERAIRPVVLGRKNSLFAGSDRGAEAAARIYSLIETAKLNGLNPYAYLRDVL 385


                 .
gi 497731324  92 R 92
Cdd:NF033517 386 T 386
DDE_Tnp_IS66 pfam03050
Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. ...
 19-65 5.92e-10

Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.


Pssm-ID: 427113 [Multi-domain]  Cd Length: 281  Bit Score: 54.18  E-value: 5.92e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 497731324   19 NHFEQWFTFVFDPRVEPTNWKAEQAIRPAVVNRKVWGGNRTAAGAKA 65
Cdd:pfam03050 235 NRWEALLRFLEDGRVPIDNNQAERAIRPVVLGRKNWLFAGSDEGAEA 281
 
Name Accession Description Interval E-value
transpos_IS66 NF033517
IS66 family transposase; Members of this protein family are DDE transposases from the IS66 ...
 12-92 4.70e-21

IS66 family transposase; Members of this protein family are DDE transposases from the IS66 family insertion sequences, which typically consist of two accessary genes (TnpA and TnpB) and the third gene encoding the transposase.


Pssm-ID: 468053 [Multi-domain]  Cd Length: 388  Bit Score: 85.71  E-value: 4.70e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497731324  12 TLAKHLWNHFEQWFTFVFDPRVEPTNWKAEQAIRPAVVNRKVWGGNRTAAGAKAQGVLMSVFETCRRRTLSVVDHISQTL 91
Cdd:NF033517 306 KAIRYLLNRWDALLRFLDDGRVPIDNNAAERAIRPVVLGRKNSLFAGSDRGAEAAARIYSLIETAKLNGLNPYAYLRDVL 385


                 .
gi 497731324  92 R 92
Cdd:NF033517 386 T 386
DDE_Tnp_IS66 pfam03050
Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. ...
 19-65 5.92e-10

Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.


Pssm-ID: 427113 [Multi-domain]  Cd Length: 281  Bit Score: 54.18  E-value: 5.92e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 497731324   19 NHFEQWFTFVFDPRVEPTNWKAEQAIRPAVVNRKVWGGNRTAAGAKA 65
Cdd:pfam03050 235 NRWEALLRFLEDGRVPIDNNQAERAIRPVVLGRKNWLFAGSDEGAEA 281
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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