NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|497898911|ref|WP_010213067|]
View 

MULTISPECIES: tautomerase family protein [Pseudomonas syringae group]

Protein Classification

tautomerase family protein( domain architecture ID 10216049)

tautomerase family protein similar to Bacillus subtilis tautomerases YusQ and YolI

CATH:  3.30.429.10
Gene Ontology:  GO:0016853
PubMed:  29184004|12051677|18695941
SCOP:  3001770

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Tautomerase_2 pfam14552
Tautomerase enzyme;
38-118 2.15e-33

Tautomerase enzyme;


:

Pssm-ID: 434035  Cd Length: 82  Bit Score: 111.89  E-value: 2.15e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497898911   38 DRYQVLNEHKANRLIIQDTGLGFTRSDKMVVITVISR-PRAAEMKKRFYALIAEGLERNCGIEAEDVMVSIVINSDEDWS 116
Cdd:pfam14552   1 DRFQIIHEHDPEDFVYPPTYLGIERSDDYVIIQITLFaGRSVEQKKALYRALAERLAAKLGIRPEDVFIVLVENPKENWS 80


                  ..
gi 497898911  117 FG 118
Cdd:pfam14552  81 FG 82
4Oxalocrotonate_Tautomerase super family cl00235
4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The ...
 2-60 4.29e-09

4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one dimer and the third from a neighboring monomer. Each monomer is a beta-alpha-beta fold with two small beta strands at the C-terminus that fold back on themselves. A pair of monomers form a dimer with two-fold symmetry, consisting of a 4-stranded beta sheet with two helices on one side and two additional small beta strands at each end. The dimers are assembled around a 3-fold axis of rotation to form a hexamer, with the short beta strands from each dimer contacting the neighboring dimers.


The actual alignment was detected with superfamily member pfam01361:

Pssm-ID: 444774  Cd Length: 60  Bit Score: 49.21  E-value: 4.29e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 497898911    2 PLLKIDVIEGRSDQEIEMLLDTIHEAMVNAFQVPERDRYQVLNEHKANRLIIQDTGLGF 60
Cdd:pfam01361   1 PFVNIKLFEGRTDEQKKELIERVTDALVEVLGAPRSAIVVIIEEVPPENWGVGGESVGD 59
 
Name Accession Description Interval E-value
Tautomerase_2 pfam14552
Tautomerase enzyme;
38-118 2.15e-33

Tautomerase enzyme;


Pssm-ID: 434035  Cd Length: 82  Bit Score: 111.89  E-value: 2.15e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497898911   38 DRYQVLNEHKANRLIIQDTGLGFTRSDKMVVITVISR-PRAAEMKKRFYALIAEGLERNCGIEAEDVMVSIVINSDEDWS 116
Cdd:pfam14552   1 DRFQIIHEHDPEDFVYPPTYLGIERSDDYVIIQITLFaGRSVEQKKALYRALAERLAAKLGIRPEDVFIVLVENPKENWS 80


                  ..
gi 497898911  117 FG 118
Cdd:pfam14552  81 FG 82
Tautomerase pfam01361
Tautomerase enzyme; This family includes the enzyme 4-oxalocrotonate tautomerase that ...
 2-60 4.29e-09

Tautomerase enzyme; This family includes the enzyme 4-oxalocrotonate tautomerase that catalyzes the ketonization of 2-hydroxymuconate to 2-oxo-3-hexenedioate.


Pssm-ID: 396090  Cd Length: 60  Bit Score: 49.21  E-value: 4.29e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 497898911    2 PLLKIDVIEGRSDQEIEMLLDTIHEAMVNAFQVPERDRYQVLNEHKANRLIIQDTGLGF 60
Cdd:pfam01361   1 PFVNIKLFEGRTDEQKKELIERVTDALVEVLGAPRSAIVVIIEEVPPENWGVGGESVGD 59
PRK02220 PRK02220
4-oxalocrotonate tautomerase; Provisional
 1-65 3.79e-05

4-oxalocrotonate tautomerase; Provisional


Pssm-ID: 235013  Cd Length: 61  Bit Score: 38.98  E-value: 3.79e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497898911   1 MPLLKIDVIEGRSDQEIEMLLDTIHEAMVNAFQVPERDRYQVLNEHKANRLIIQdtglGFTRSDK 65
Cdd:PRK02220   1 MPYVHIKLIEGRTEEQLKALVKDVTAAVSKNTGAPAEHIHVIINEMSKNHYAVG----GKRLSDK 61
PptA COG1942
Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites ...
 68-118 8.92e-05

Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441545  Cd Length: 58  Bit Score: 37.82  E-value: 8.92e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 497898911  68 VITV-ISRPRAAEMKKRFYALIAEGLERNCGIEAEDVMVSIVINSDEDWSFG 118
Cdd:COG1942    2 IINIkLFEGRTPEQKRALAKAVTDAVVEVLGKPPESVSVVIEEVPPENWGIG 53
PptA COG1942
Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites ...
 2-48 6.85e-04

Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441545  Cd Length: 58  Bit Score: 35.51  E-value: 6.85e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 497898911   2 PLLKIDVIEGRSDQEIEMLLDTIHEAMVNAFQVPERDRYQVLNEHKA 48
Cdd:COG1942    1 PIINIKLFEGRTPEQKRALAKAVTDAVVEVLGKPPESVSVVIEEVPP 47
 
Name Accession Description Interval E-value
Tautomerase_2 pfam14552
Tautomerase enzyme;
38-118 2.15e-33

Tautomerase enzyme;


Pssm-ID: 434035  Cd Length: 82  Bit Score: 111.89  E-value: 2.15e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497898911   38 DRYQVLNEHKANRLIIQDTGLGFTRSDKMVVITVISR-PRAAEMKKRFYALIAEGLERNCGIEAEDVMVSIVINSDEDWS 116
Cdd:pfam14552   1 DRFQIIHEHDPEDFVYPPTYLGIERSDDYVIIQITLFaGRSVEQKKALYRALAERLAAKLGIRPEDVFIVLVENPKENWS 80


                  ..
gi 497898911  117 FG 118
Cdd:pfam14552  81 FG 82
Tautomerase pfam01361
Tautomerase enzyme; This family includes the enzyme 4-oxalocrotonate tautomerase that ...
 2-60 4.29e-09

Tautomerase enzyme; This family includes the enzyme 4-oxalocrotonate tautomerase that catalyzes the ketonization of 2-hydroxymuconate to 2-oxo-3-hexenedioate.


Pssm-ID: 396090  Cd Length: 60  Bit Score: 49.21  E-value: 4.29e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 497898911    2 PLLKIDVIEGRSDQEIEMLLDTIHEAMVNAFQVPERDRYQVLNEHKANRLIIQDTGLGF 60
Cdd:pfam01361   1 PFVNIKLFEGRTDEQKKELIERVTDALVEVLGAPRSAIVVIIEEVPPENWGVGGESVGD 59
PRK02220 PRK02220
4-oxalocrotonate tautomerase; Provisional
 1-65 3.79e-05

4-oxalocrotonate tautomerase; Provisional


Pssm-ID: 235013  Cd Length: 61  Bit Score: 38.98  E-value: 3.79e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497898911   1 MPLLKIDVIEGRSDQEIEMLLDTIHEAMVNAFQVPERDRYQVLNEHKANRLIIQdtglGFTRSDK 65
Cdd:PRK02220   1 MPYVHIKLIEGRTEEQLKALVKDVTAAVSKNTGAPAEHIHVIINEMSKNHYAVG----GKRLSDK 61
PptA COG1942
Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites ...
 68-118 8.92e-05

Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441545  Cd Length: 58  Bit Score: 37.82  E-value: 8.92e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 497898911  68 VITV-ISRPRAAEMKKRFYALIAEGLERNCGIEAEDVMVSIVINSDEDWSFG 118
Cdd:COG1942    2 IINIkLFEGRTPEQKRALAKAVTDAVVEVLGKPPESVSVVIEEVPPENWGIG 53
PptA COG1942
Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites ...
 2-48 6.85e-04

Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441545  Cd Length: 58  Bit Score: 35.51  E-value: 6.85e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 497898911   2 PLLKIDVIEGRSDQEIEMLLDTIHEAMVNAFQVPERDRYQVLNEHKA 48
Cdd:COG1942    1 PIINIKLFEGRTPEQKRALAKAVTDAVVEVLGKPPESVSVVIEEVPP 47
PRK01964 PRK01964
4-oxalocrotonate tautomerase; Provisional
 1-45 9.58e-03

4-oxalocrotonate tautomerase; Provisional


Pssm-ID: 179355  Cd Length: 64  Bit Score: 32.85  E-value: 9.58e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 497898911   1 MPLLKIDVIEGRSDQEIEMLLDTIHEAMVNAFQVPERDRYQVLNE 45
Cdd:PRK01964   1 MPIVQIQLLEGRPEEKIKNLIREVTEAISATLDVPKERVRVIVNE 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH