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Conserved domains on  [gi|497985908|ref|WP_010300064|]
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MULTISPECIES: phosphate ABC transporter permease PstC [Pectobacterium]

Protein Classification

phosphate ABC transporter permease subunit PstC( domain architecture ID 10793554)

phosphate ABC transporter permease subunit PstC is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter for phosphate; ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment; the captured solute is delivered to a gated translocation pathway formed by the two TMs

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
pstC PRK11275
phosphate ABC transporter permease PstC;
1-319 0e+00

phosphate ABC transporter permease PstC;


:

Pssm-ID: 183070  Cd Length: 319  Bit Score: 568.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908   1 MAEYKPTIKAPGKYGDILFSTLVKLAALVTLLLLGGIIVSLIVASWPSIEKFGFAFLWTKEWDAPAEQFGALVPIYGTIV 80
Cdd:PRK11275   1 MAATKPAFNAPGKKGDIIFSALVKLAALITLLLLGGIIVSLIISSWPSIQKFGLSFLWTKEWDAPNDIYGALVPIYGTLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  81 TSLIALIIAIPISFGIALFLTELAPAWLKRPLGVAIELLAAIPSIVYGMWGLFIFAPLFAKYFQQPVGNVLSGIPIVGSL 160
Cdd:PRK11275  81 TSFIALLIAVPVSFGIALFLTELAPGWLKRPLGIAIELLAAIPSIVYGMWGLFVFAPLFATYFQEPVGNVLSNIPIVGAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 161 FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALG 240
Cdd:PRK11275 161 FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPFTKNGVIGGVMLGLGRALG 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497985908 241 ETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFAEAESGLHTAALMELGLILFVITFIVLACSKLMVMRLAKNEGAR 319
Cdd:PRK11275 241 ETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFAEAESGLHTAALMELGLILFVITFIVLAASKLMIMRLAKNEGAR 319
 
Name Accession Description Interval E-value
pstC PRK11275
phosphate ABC transporter permease PstC;
1-319 0e+00

phosphate ABC transporter permease PstC;


Pssm-ID: 183070  Cd Length: 319  Bit Score: 568.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908   1 MAEYKPTIKAPGKYGDILFSTLVKLAALVTLLLLGGIIVSLIVASWPSIEKFGFAFLWTKEWDAPAEQFGALVPIYGTIV 80
Cdd:PRK11275   1 MAATKPAFNAPGKKGDIIFSALVKLAALITLLLLGGIIVSLIISSWPSIQKFGLSFLWTKEWDAPNDIYGALVPIYGTLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  81 TSLIALIIAIPISFGIALFLTELAPAWLKRPLGVAIELLAAIPSIVYGMWGLFIFAPLFAKYFQQPVGNVLSGIPIVGSL 160
Cdd:PRK11275  81 TSFIALLIAVPVSFGIALFLTELAPGWLKRPLGIAIELLAAIPSIVYGMWGLFVFAPLFATYFQEPVGNVLSNIPIVGAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 161 FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALG 240
Cdd:PRK11275 161 FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPFTKNGVIGGVMLGLGRALG 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497985908 241 ETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFAEAESGLHTAALMELGLILFVITFIVLACSKLMVMRLAKNEGAR 319
Cdd:PRK11275 241 ETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFAEAESGLHTAALMELGLILFVITFIVLAASKLMIMRLAKNEGAR 319
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 9-317 2.28e-105

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 309.71  E-value: 2.28e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908   9 KAPGKYGDILFSTLVKLAALVTLLLLGGIIVSLIVASWPSIEKFGFA-FLWTKEWD--APAEQFGALVPIYGTIVTSLIA 85
Cdd:COG0573   10 RRRRRLGDRLFRGLLLLAALLSILILLLIVLFLLIESLPAFQEVGLLeFLTGTEWNpvSSNGEFGILPLIVGTLLVSLIA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  86 LIIAIPISFGIALFLTELAPAWLKRPLGVAIELLAAIPSIVYGMWGLFIFAPLFAKYFQQPvgnvlsgipivgslfsgpA 165
Cdd:COG0573   90 LLIAVPLGLGIAIFLSEYAPPRLRRILKPAIELLAGIPSVVYGFWGLFVLVPLLRDLFPWP------------------P 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 166 FGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAV 245
Cdd:COG0573  152 SGFSLLTAGIVLAIMILPTITSLSRDALRAVPRSLREAALALGATRWETIRKVVLPAARSGIIAAVILGLGRALGETMAV 231

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497985908 246 TFIIGNTYQLdSASLYMPGNSITSALANEFAEAE-SGLHTAALMELGLILFVITFIVLACSKLMVMRLAKNEG 317
Cdd:COG0573  232 LMVAGNAPQI-PFSLFDPGRTLTALIALEFGEAPfGSLHYSALFALGLVLFVITLLVNLLARLIVRRYREKYG 303
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 36-311 3.21e-85

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 258.35  E-value: 3.21e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908   36 GIIVSLIVASWPSIEKFG-FAFLWTKEWDAPA----EQFGALVPIYGTIVTSLIALIIAIPISFGIALFLTELAPAWLKR 110
Cdd:TIGR02138  21 LIVLFLLYEAIPAFEKNGiLNFLTGTVWDPGSgpvqEQYGALPLIVGTLITSLIALLIAVPVGIGIAIFLSEIAPKRVRS 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  111 PLGVAIELLAAIPSIVYGMWGLFIFAPLFAKYFQQPVGNVLSGIPivgslfsgpAFGIGILAAGVILAIMIIPYIAAVMR 190
Cdd:TIGR02138 101 VLKPVVELLAGIPSVVYGFWGLFVLVPFLKPHFQPFLGSNLGLIP---------LFGGPILTAGIVLAIMILPTIASISR 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  191 DVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSA 270
Cdd:TIGR02138 172 DALRAVPRSYKEASYALGATKWETIRRVILPAARSGIVGAVVLGLGRALGETMAVTMVIGNVFPISPLSLFDPGTTITSL 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 497985908  271 LANEFAEAESG-LHTAALMELGLILFVITFIVLACSKLMVMR 311
Cdd:TIGR02138 252 IANQFGEASGGsVHTSALFALGLVLFVITLLVNILARYIVRR 293
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 75-272 3.23e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.53  E-value: 3.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  75 IYGTIVTSLIALIIAIPISFGIALFLTELAPaWLKRPLGVAIELLAAIPSIVYGMWGLFIFaplfakyfqqpvgnvlsgi 154
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRG-KLDRLLRRIIDLLLSLPSLVLGLLLVLLF------------------- 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 155 pivGSLFSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLG 234
Cdd:cd06261   61 ---GVLLGWGILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLA 137

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 497985908 235 LGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALA 272
Cdd:cd06261  138 FARALGEFALVSFLGGGEAPGPGTGLLLIFAILFPGDL 175
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 154-252 3.24e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.91  E-value: 3.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  154 IPIVGSLFSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVML 233
Cdd:pfam00528  36 AILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLAL 115

                          90
                  ....*....|....*....
gi 497985908  234 GLGRALGETMAVTFIIGNT 252
Cdd:pfam00528 116 AFGGALGGAVLLEFLGSWP 134
 
Name Accession Description Interval E-value
pstC PRK11275
phosphate ABC transporter permease PstC;
1-319 0e+00

phosphate ABC transporter permease PstC;


Pssm-ID: 183070  Cd Length: 319  Bit Score: 568.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908   1 MAEYKPTIKAPGKYGDILFSTLVKLAALVTLLLLGGIIVSLIVASWPSIEKFGFAFLWTKEWDAPAEQFGALVPIYGTIV 80
Cdd:PRK11275   1 MAATKPAFNAPGKKGDIIFSALVKLAALITLLLLGGIIVSLIISSWPSIQKFGLSFLWTKEWDAPNDIYGALVPIYGTLV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  81 TSLIALIIAIPISFGIALFLTELAPAWLKRPLGVAIELLAAIPSIVYGMWGLFIFAPLFAKYFQQPVGNVLSGIPIVGSL 160
Cdd:PRK11275  81 TSFIALLIAVPVSFGIALFLTELAPGWLKRPLGIAIELLAAIPSIVYGMWGLFVFAPLFATYFQEPVGNVLSNIPIVGAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 161 FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALG 240
Cdd:PRK11275 161 FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPFTKNGVIGGVMLGLGRALG 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497985908 241 ETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFAEAESGLHTAALMELGLILFVITFIVLACSKLMVMRLAKNEGAR 319
Cdd:PRK11275 241 ETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFAEAESGLHTAALMELGLILFVITFIVLAASKLMIMRLAKNEGAR 319
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 9-317 2.28e-105

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 309.71  E-value: 2.28e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908   9 KAPGKYGDILFSTLVKLAALVTLLLLGGIIVSLIVASWPSIEKFGFA-FLWTKEWD--APAEQFGALVPIYGTIVTSLIA 85
Cdd:COG0573   10 RRRRRLGDRLFRGLLLLAALLSILILLLIVLFLLIESLPAFQEVGLLeFLTGTEWNpvSSNGEFGILPLIVGTLLVSLIA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  86 LIIAIPISFGIALFLTELAPAWLKRPLGVAIELLAAIPSIVYGMWGLFIFAPLFAKYFQQPvgnvlsgipivgslfsgpA 165
Cdd:COG0573   90 LLIAVPLGLGIAIFLSEYAPPRLRRILKPAIELLAGIPSVVYGFWGLFVLVPLLRDLFPWP------------------P 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 166 FGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAV 245
Cdd:COG0573  152 SGFSLLTAGIVLAIMILPTITSLSRDALRAVPRSLREAALALGATRWETIRKVVLPAARSGIIAAVILGLGRALGETMAV 231

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 497985908 246 TFIIGNTYQLdSASLYMPGNSITSALANEFAEAE-SGLHTAALMELGLILFVITFIVLACSKLMVMRLAKNEG 317
Cdd:COG0573  232 LMVAGNAPQI-PFSLFDPGRTLTALIALEFGEAPfGSLHYSALFALGLVLFVITLLVNLLARLIVRRYREKYG 303
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 36-311 3.21e-85

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 258.35  E-value: 3.21e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908   36 GIIVSLIVASWPSIEKFG-FAFLWTKEWDAPA----EQFGALVPIYGTIVTSLIALIIAIPISFGIALFLTELAPAWLKR 110
Cdd:TIGR02138  21 LIVLFLLYEAIPAFEKNGiLNFLTGTVWDPGSgpvqEQYGALPLIVGTLITSLIALLIAVPVGIGIAIFLSEIAPKRVRS 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  111 PLGVAIELLAAIPSIVYGMWGLFIFAPLFAKYFQQPVGNVLSGIPivgslfsgpAFGIGILAAGVILAIMIIPYIAAVMR 190
Cdd:TIGR02138 101 VLKPVVELLAGIPSVVYGFWGLFVLVPFLKPHFQPFLGSNLGLIP---------LFGGPILTAGIVLAIMILPTIASISR 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  191 DVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSA 270
Cdd:TIGR02138 172 DALRAVPRSYKEASYALGATKWETIRRVILPAARSGIVGAVVLGLGRALGETMAVTMVIGNVFPISPLSLFDPGTTITSL 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 497985908  271 LANEFAEAESG-LHTAALMELGLILFVITFIVLACSKLMVMR 311
Cdd:TIGR02138 252 IANQFGEASGGsVHTSALFALGLVLFVITLLVNILARYIVRR 293
PstA COG0581
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 70-255 1.57e-27

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440346 [Multi-domain]  Cd Length: 259  Bit Score: 107.81  E-value: 1.57e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  70 GALVPIYGTIVTSLIALIIAIPISFGIALFLTELAPA-WLKRPLGVAIELLAAIPSIVYGmwgLFIFApLFAKYFQqpvg 148
Cdd:COG0581   38 GILPAIVGTLLLVLLATLIAVPLGVLAAIYLAEYARGgRLARLIRFAIDVLAGVPSIVYG---LFGYA-LFVLTLG---- 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 149 nvlsgipivgslfsgpaFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVI 228
Cdd:COG0581  110 -----------------LGFSLLAGALALALLMLPVVIRTTEEALRLVPNSLREASYALGATKWQTIRKVVLPAALPGIL 172

                        170       180
                 ....*....|....*....|....*..
gi 497985908 229 GGVMLGLGRALGETMAVTFIIGNTYQL 255
Cdd:COG0581  173 TGVILAIARAAGETAPLLFTAGVSPFL 199
3a0107s02c TIGR00974
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of ...
 57-253 1.97e-20

phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of permease proteins in the ABC (high affinity) phosphate transporter. In a number of species, this permease is fused with the PtsC protein (TIGR02138). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273373  Cd Length: 271  Bit Score: 88.83  E-value: 1.97e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908   57 LWTKEWDAPAEQFGALVPIYGTIVTSLIALIIAIPISFGIALFLTELA-PAWLKRPLGVAIELLAAIPSIVYGmwgLFIF 135
Cdd:TIGR00974  38 FFTKSPTPTGAEGGIGPAIVGTLLLTLLAIVIAVPLGIGAAIYLAEYAnGSRFTKIIRFAVDILAGVPSIVVG---LFGY 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  136 APLFAKYFqqpvgnvlsgipivgslfsgpAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVI 215
Cdd:TIGR00974 115 GFFVLTYL---------------------GGGFSLLAGALALALLILPVIIRTTEEALKAVPKDLREASLALGATKWQTI 173

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 497985908  216 WRIVLPYTKNGVIGGVMLGLGRALGETMAVTFIIGNTY 253
Cdd:TIGR00974 174 FKVVLPAALPGILTGIILSIARAAGETAPLLFTAGGSA 211
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 75-272 3.23e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.53  E-value: 3.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  75 IYGTIVTSLIALIIAIPISFGIALFLTELAPaWLKRPLGVAIELLAAIPSIVYGMWGLFIFaplfakyfqqpvgnvlsgi 154
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRG-KLDRLLRRIIDLLLSLPSLVLGLLLVLLF------------------- 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 155 pivGSLFSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLG 234
Cdd:cd06261   61 ---GVLLGWGILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLA 137

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 497985908 235 LGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALA 272
Cdd:cd06261  138 FARALGEFALVSFLGGGEAPGPGTGLLLIFAILFPGDL 175
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 107-253 1.62e-09

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 57.45  E-value: 1.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 107 WLKRPLGVAIELLAAIPSIVYGMWGLFIFAPLfakyfqqpvgnvlsgiPIVGSLFSgpAFGIGIL--AAGVILAIMII-- 182
Cdd:COG0555   87 PGKRLVDALVDLPFALPTAVAGIALLLLFGPN----------------GWLGQLLA--PLGIKVAftPLGIVLAQTFVsl 148

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497985908 183 PYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAVTFIIGNTY 253
Cdd:COG0555  149 PFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFARALGEFGAVIFIAGNLP 219
COG4590 COG4590
ABC-type uncharacterized transport system, permease component [General function prediction ...
 208-301 1.37e-07

ABC-type uncharacterized transport system, permease component [General function prediction only];


Pssm-ID: 443647 [Multi-domain]  Cd Length: 757  Bit Score: 52.92  E-value: 1.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 208 GCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAVTFIIGNTYQLDsASLYmPGNSITSA-LANEFAEAESG-LHTA 285
Cdd:COG4590  646 GATPWQTLTRVVLLTASPGIFSAVMIGLGRAVGETMIVLMATGNTPVMD-FNIF-EGMRTLSAnIAVEMPESEVGsTHYR 723

                         90
                 ....*....|....*.
gi 497985908 286 ALMELGLILFVITFIV 301
Cdd:COG4590  724 VLFLAALVLFVFTFVF 739
cysT CHL00187
sulfate transport protein; Provisional
 156-251 1.72e-07

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 51.17  E-value: 1.72e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 156 IVGSLFSGPAFGIGILAAGVILAIMII--PYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVML 233
Cdd:CHL00187 121 WIGHLLSHLGIQIVFTKLGVLLAMIFVsfPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLAL 200

                         90
                 ....*....|....*...
gi 497985908 234 GLGRALGETMAVTFIIGN 251
Cdd:CHL00187 201 TFSRAIGEYGSIVIISSN 218
pstA PRK11268
phosphate ABC transporter permease PstA;
118-247 1.56e-06

phosphate ABC transporter permease PstA;


Pssm-ID: 183065 [Multi-domain]  Cd Length: 295  Bit Score: 48.91  E-value: 1.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 118 LLAAiPSIVYGmwgLFIFAPLFAKyFQQpvgnvlsgipivgslFSGPAfgiGILAagviLAIMIIPYIAAVMRDVFEQTP 197
Cdd:PRK11268 128 LLSA-PSIVVG---LFVYTIVVAQ-MEH---------------FSGWA---GVIA----LALLQIPIVIRTTENMLKLVP 180

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 497985908 198 VMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAVTF 247
Cdd:PRK11268 181 DSLREAAYALGTPKWKMISAITLKASVSGIMTGVLLAIARIAGETAPLLF 230
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
171-251 2.49e-06

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 48.21  E-value: 2.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 171 LAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAVTFIIG 250
Cdd:PRK10971 141 LGIAVAMAFTSIPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRSLGEFGAVIFIAG 220


                 .
gi 497985908 251 N 251
Cdd:PRK10971 221 N 221
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 107-315 2.90e-06

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 47.80  E-value: 2.90e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 107 WLKRPLGVAIELLAAIPSIVYGMwGLFIFaplfakyfqqpvgnvLSGIPIVGSLFsgpafgigilaaGVILA--IMIIPY 184
Cdd:COG1177   94 RGRRLLLALLLLPLVVPGIVLGV-ALLLL---------------FSALGLSGGLW------------GLILAhvVFTLPF 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 185 IAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAVTFIIGNTYQldSASLYMpg 264
Cdd:COG1177  146 VVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGVT--TLPVYI-- 221

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 497985908 265 nsitsalaneFAEAESGLhTAALMELGLILFVITFIVLACSKLMVMRLAKN 315
Cdd:COG1177  222 ----------YSMIRRGI-SPEINALSTLLILLSLLLLLLAERLRRRGERR 261
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 154-252 3.24e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.91  E-value: 3.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  154 IPIVGSLFSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVML 233
Cdd:pfam00528  36 AILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLAL 115

                          90
                  ....*....|....*....
gi 497985908  234 GLGRALGETMAVTFIIGNT 252
Cdd:pfam00528 116 AFGGALGGAVLLEFLGSWP 134
Mo_ABC_porter TIGR01581
NifC-like ABC-type porter; This model describes a clade of ABC porter genes with relatively ...
 108-253 1.16e-05

NifC-like ABC-type porter; This model describes a clade of ABC porter genes with relatively weak homology compared to its neighbor clades, the molybdate (TIGR02141) and sulfate (TIGR00969) porters. Neighbor-Joining, PAM-distance phylogenetic trees support the separation of the clades in this way. Included in this group is a gene designated NifC in Clostridium pasturianum. It would be reasonable to presume that NifC acts as a molybdate porter since the most common form of nitrogenase is a molybdoenzyme. Several other sequences falling within the scope of this model are annotated as molybdate porters and one, from Halobacterium, is annotated as a sulfate porter. There is presently no experimental evidence to support annotations with this degree of specificity.


Pssm-ID: 130643  Cd Length: 225  Bit Score: 45.85  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  108 LKRPLGVAIELLAAIPSIVYGMWGLFIFAPLfakyfqQPVGNVLS--GIPIVGSlfsgpafgigilAAGVILAIMII--P 183
Cdd:TIGR01581  55 LKKLLDTLLDLPMVLPPLVAGLALLLLFGRN------GLLGPYLEaaGIQVIFS------------TLGVVLAQTFVasP 116

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  184 YIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAVTFIIGNTY 253
Cdd:TIGR01581 117 YYVRVARSTFKSVDPRYEDVARSLGAGPLETFRKITLPMARPGLLAGLVLAWARALGEFGATLMFAGSIQ 186
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 166-239 4.41e-04

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 41.29  E-value: 4.41e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497985908 166 FGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRAL 239
Cdd:COG0600  121 FGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAW 194
modB PRK09421
molybdate ABC transporter permease subunit;
178-318 4.77e-04

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 40.68  E-value: 4.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 178 AIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMA-VTF---IIGNTY 253
Cdd:PRK09421 100 AVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLGEFGAtITFvsnIPGETQ 179

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 497985908 254 QLDSAslympgnsITSALANEFAEAESglhtaalMELGLILFVITFIVLACSKLMVMRLAKNEGA 318
Cdd:PRK09421 180 TIPSA--------MYTLIQTPGGESAA-------ARLCIISIAIALASLLLSEWLARRSRKRLGA 229
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
38-303 1.13e-03

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 40.53  E-value: 1.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  38 IVSLIVASWPSIEKFGFAFLWtkeWDAPAEQFGALVPIYGTIVTSLIALIIAIPISFGIAlFLTELAPAWLKRPLGVAIE 117
Cdd:COG1178  306 LLALLLWSLTKALDDNLTLDN---YRFVLLDPSLLRALLNSLLLALLAALLAVLLALLLA-YLVRRRRGRLARLLDRLAM 381

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 118 LLAAIPSIVYGMwGLFIFaplfakyFQQPVGNVLSGipivgslfsgpafGIGILAAGviLAIMIIPYIAAVMRDVFEQTP 197
Cdd:COG1178  382 LPYAVPGIVLGL-GLLLL-------FNRPLPLLLYG-------------TLAILVLA--YVVRFLPFALRSLEAALAQID 438

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 198 VMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAVTFiigntyqldsasLYMPGNSITSALANEFAE 277
Cdd:COG1178  439 PSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLL------------LRPPGFETLAVLIYQLAS 506

                        250       260
                 ....*....|....*....|....*.
gi 497985908 278 AESgLHTAALMelGLILFVITFIVLA 303
Cdd:COG1178  507 SGR-YGEAAAL--ALLLVLVSLLPVL 529
cysW PRK11602
sulfate/thiosulfate ABC transporter permease CysW;
192-255 5.08e-03

sulfate/thiosulfate ABC transporter permease CysW;


Pssm-ID: 183225  Cd Length: 283  Bit Score: 38.19  E-value: 5.08e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497985908 192 VFEQTPVMMK------ESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGETMAVTF----IIGNTYQL 255
Cdd:PRK11602 162 VRELVPVMLSqgsqedEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVvsgsIRGETLSL 235
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
94-311 7.20e-03

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 37.83  E-value: 7.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908  94 FGIAL-FLTELAPAWLKRPLGVAIELLAAIPSIV--YGMWGLFIFAPLFAKYFQQPVGNVLSGIpivgslfsgpafgIGI 170
Cdd:COG1178   73 LGVPLaWLLARTDFPGRRLLRWLLLLPLALPPYVvaLAWIALFGPNGLLNTLLRALFGLEPPDI-------------YGL 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497985908 171 LAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPYTKNGVIGGVMLGLGRALGEtMAVTFIIG 250
Cdd:COG1178  140 GGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLAD-FGTPLVLG 218

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497985908 251 NTYQldsaslympgnSITSALANEFAeAESGLHTAALmeLGLILFVITFIVLACSKLMVMR 311
Cdd:COG1178  219 GGYT-----------TLTTAIYQAWL-GDFDLGAAAA--LALVLLLLVLLLLLLERRLRRR 265
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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