NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|498287081|ref|WP_010601237|]
View 

MULTISPECIES: TerD family protein [Pedobacter]

Protein Classification

TerD family protein( domain architecture ID 10492220)

TerD family protein similar to stress response proteins such as Bacillus subtilis general stress protein 16U and tellurium resistance proteins TerD, TerE, and TerX

CATH:  2.60.60.30
Gene Ontology:  GO:0006950
SCOP:  4006781

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TerD pfam02342
TerD domain; The TerD domain is found in TerD family proteins that include the paralogous TerD, ...
 1-184 1.89e-96

TerD domain; The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.


:

Pssm-ID: 426730  Cd Length: 187  Bit Score: 277.46  E-value: 1.89e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081    1 MAINLQKGQKINI-----GLSKITVGLGWDPNEGTGYDFDLDASAFMIDANRLIPAEEYFVFYGNTDSPDQALHHTGDDP 75
Cdd:pfam02342   1 MAISLQKGQNISLtkeapGLTKVMVGLGWDVNKTGGADFDLDASAFLLGANGKVRSDEDFVFYNNLKSPDGSVRHLGDNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081   76 TGGNSatGDDESIQVDLSKVDDSIQEILFVVTIHDAVTRKQNYGQVRNSYIRIVDDSTGEEVAKYELGEDFSIETGVEFG 155
Cdd:pfam02342  81 TGEGD--GDDEQIEVDLSKVPADVEKIVFVVTIYDAEARRQNFGQVRNAYIRVVDAATGEELARYDLSEDFSGETALIFG 158

                         170       180
                  ....*....|....*....|....*....
gi 498287081  156 RLYKRDGQWKFEASGIGYREDLSFFLSKY 184
Cdd:pfam02342 159 ELYRHGGEWKFRAVGQGYAGGLAGLATDY 187
 
Name Accession Description Interval E-value
TerD pfam02342
TerD domain; The TerD domain is found in TerD family proteins that include the paralogous TerD, ...
 1-184 1.89e-96

TerD domain; The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.


Pssm-ID: 426730  Cd Length: 187  Bit Score: 277.46  E-value: 1.89e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081    1 MAINLQKGQKINI-----GLSKITVGLGWDPNEGTGYDFDLDASAFMIDANRLIPAEEYFVFYGNTDSPDQALHHTGDDP 75
Cdd:pfam02342   1 MAISLQKGQNISLtkeapGLTKVMVGLGWDVNKTGGADFDLDASAFLLGANGKVRSDEDFVFYNNLKSPDGSVRHLGDNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081   76 TGGNSatGDDESIQVDLSKVDDSIQEILFVVTIHDAVTRKQNYGQVRNSYIRIVDDSTGEEVAKYELGEDFSIETGVEFG 155
Cdd:pfam02342  81 TGEGD--GDDEQIEVDLSKVPADVEKIVFVVTIYDAEARRQNFGQVRNAYIRVVDAATGEELARYDLSEDFSGETALIFG 158

                         170       180
                  ....*....|....*....|....*....
gi 498287081  156 RLYKRDGQWKFEASGIGYREDLSFFLSKY 184
Cdd:pfam02342 159 ELYRHGGEWKFRAVGQGYAGGLAGLATDY 187
TerZ COG2310
Stress response protein SCP2 [Signal transduction mechanisms];
1-184 4.13e-95

Stress response protein SCP2 [Signal transduction mechanisms];


Pssm-ID: 441884  Cd Length: 187  Bit Score: 274.35  E-value: 4.13e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081   1 MAINLQKGQKINI-----GLSKITVGLGWDPNEGTGYDFDLDASAFMIDANRLIPAEEYFVFYGNTDSPDQALHHTGDDP 75
Cdd:COG2310    1 MAISLQKGQNISLtkeapGLTKVRVGLGWDPAKTDGGDFDLDASAFLLDANGKVRSDEDFVFYNNLKSPDGSVRHTGDNR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081  76 TGGNSatGDDESIQVDLSKVDDSIQEILFVVTIHDAVTRKQNYGQVRNSYIRIVDDSTGEEVAKYELGEDFSIETGVEFG 155
Cdd:COG2310   81 TGEGD--GDDEQITVDLSKVPADVEKIVFVVTIYDAEARGQNFGQVSNAFIRVVDAATGEELARYDLSEDFSGETAMVFG 158

                        170       180
                 ....*....|....*....|....*....
gi 498287081 156 RLYKRDGQWKFEASGIGYREDLSFFLSKY 184
Cdd:COG2310  159 ELYRHGGEWKFRAVGQGYNGGLAGLATDY 187
TerD_like cd06974
Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; ...
 15-184 1.00e-54

Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Tellurium resistance terD like proteins. This family is composed of uncharacterized proteins involved in stress response, such as the tellurium resistance proteins, chemical-damaging agent resistance proteins, and general stress proteins from a variety of organisms. The tellurium resistance proteins are homologous terA,-D,-E,-F,-Z,-X gene products, which confer tellurium resistance mediated by plasmids. Currently, the biochemical mechanism of tellurium resistance remains unknown. The family also contains several ter gene homologues, YceC, YceD, YceE, for which there is no clear evidence for any involvement in the tellurium resistance. A putative cAMP-binding protin CABP1 shows a significant similarity to the terD protein and is also included in this family.


Pssm-ID: 132992  Cd Length: 162  Bit Score: 170.94  E-value: 1.00e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081  15 LSKITVGLGWDPNEgTGYDFDLDASAFMIDANRLIPAEEYFVFYGNTDSPDQALHHTGDDPTGGNsatGDDESIQVDLSK 94
Cdd:cd06974    1 LSKVRVGLGWDPGS-TGGGIDLDLSAFLLDADGKVRGDADVVFYNQLSSPDGAVRLSGDNRTGGD---GDDETITVDLDR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081  95 VDDSIQEILFVVTIHDAvtrkQNYGQVRNSYIRIVDDSTGEEVAKYELGEDfSIETGVEFGRLYKRDGQWKFEASGIGYR 174
Cdd:cd06974   77 LPPDIRRIVFTVTIYEG----QPFGQVENAFVRLVDAGGNTELARYDLTED-SGETALILAELYRRNGEWKFRAVGQGFN 151

                        170
                 ....*....|
gi 498287081 175 EDLSFFLSKY 184
Cdd:cd06974  152 GGLAALATHY 161
 
Name Accession Description Interval E-value
TerD pfam02342
TerD domain; The TerD domain is found in TerD family proteins that include the paralogous TerD, ...
 1-184 1.89e-96

TerD domain; The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.


Pssm-ID: 426730  Cd Length: 187  Bit Score: 277.46  E-value: 1.89e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081    1 MAINLQKGQKINI-----GLSKITVGLGWDPNEGTGYDFDLDASAFMIDANRLIPAEEYFVFYGNTDSPDQALHHTGDDP 75
Cdd:pfam02342   1 MAISLQKGQNISLtkeapGLTKVMVGLGWDVNKTGGADFDLDASAFLLGANGKVRSDEDFVFYNNLKSPDGSVRHLGDNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081   76 TGGNSatGDDESIQVDLSKVDDSIQEILFVVTIHDAVTRKQNYGQVRNSYIRIVDDSTGEEVAKYELGEDFSIETGVEFG 155
Cdd:pfam02342  81 TGEGD--GDDEQIEVDLSKVPADVEKIVFVVTIYDAEARRQNFGQVRNAYIRVVDAATGEELARYDLSEDFSGETALIFG 158

                         170       180
                  ....*....|....*....|....*....
gi 498287081  156 RLYKRDGQWKFEASGIGYREDLSFFLSKY 184
Cdd:pfam02342 159 ELYRHGGEWKFRAVGQGYAGGLAGLATDY 187
TerZ COG2310
Stress response protein SCP2 [Signal transduction mechanisms];
1-184 4.13e-95

Stress response protein SCP2 [Signal transduction mechanisms];


Pssm-ID: 441884  Cd Length: 187  Bit Score: 274.35  E-value: 4.13e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081   1 MAINLQKGQKINI-----GLSKITVGLGWDPNEGTGYDFDLDASAFMIDANRLIPAEEYFVFYGNTDSPDQALHHTGDDP 75
Cdd:COG2310    1 MAISLQKGQNISLtkeapGLTKVRVGLGWDPAKTDGGDFDLDASAFLLDANGKVRSDEDFVFYNNLKSPDGSVRHTGDNR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081  76 TGGNSatGDDESIQVDLSKVDDSIQEILFVVTIHDAVTRKQNYGQVRNSYIRIVDDSTGEEVAKYELGEDFSIETGVEFG 155
Cdd:COG2310   81 TGEGD--GDDEQITVDLSKVPADVEKIVFVVTIYDAEARGQNFGQVSNAFIRVVDAATGEELARYDLSEDFSGETAMVFG 158

                        170       180
                 ....*....|....*....|....*....
gi 498287081 156 RLYKRDGQWKFEASGIGYREDLSFFLSKY 184
Cdd:COG2310  159 ELYRHGGEWKFRAVGQGYNGGLAGLATDY 187
TerD_like cd06974
Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; ...
 15-184 1.00e-54

Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Tellurium resistance terD like proteins. This family is composed of uncharacterized proteins involved in stress response, such as the tellurium resistance proteins, chemical-damaging agent resistance proteins, and general stress proteins from a variety of organisms. The tellurium resistance proteins are homologous terA,-D,-E,-F,-Z,-X gene products, which confer tellurium resistance mediated by plasmids. Currently, the biochemical mechanism of tellurium resistance remains unknown. The family also contains several ter gene homologues, YceC, YceD, YceE, for which there is no clear evidence for any involvement in the tellurium resistance. A putative cAMP-binding protin CABP1 shows a significant similarity to the terD protein and is also included in this family.


Pssm-ID: 132992  Cd Length: 162  Bit Score: 170.94  E-value: 1.00e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081  15 LSKITVGLGWDPNEgTGYDFDLDASAFMIDANRLIPAEEYFVFYGNTDSPDQALHHTGDDPTGGNsatGDDESIQVDLSK 94
Cdd:cd06974    1 LSKVRVGLGWDPGS-TGGGIDLDLSAFLLDADGKVRGDADVVFYNQLSSPDGAVRLSGDNRTGGD---GDDETITVDLDR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498287081  95 VDDSIQEILFVVTIHDAvtrkQNYGQVRNSYIRIVDDSTGEEVAKYELGEDfSIETGVEFGRLYKRDGQWKFEASGIGYR 174
Cdd:cd06974   77 LPPDIRRIVFTVTIYEG----QPFGQVENAFVRLVDAGGNTELARYDLTED-SGETALILAELYRRNGEWKFRAVGQGFN 151

                        170
                 ....*....|
gi 498287081 175 EDLSFFLSKY 184
Cdd:cd06974  152 GGLAALATHY 161
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH