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Conserved domains on  [gi|498359488|ref|WP_010673644|]
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MULTISPECIES: NAD(+) kinase [Aeromonas]

Protein Classification

NAD(+) kinase( domain architecture ID 10011922)

NAD(+) kinase catalyzes specifically the phosphorylation on the 2'-hydroxyl of the adenosine moiety of NAD to yield NADP, and is involved in regulating the intracellular balance of NAD and NADP

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-294 0e+00

inorganic polyphosphate/ATP-NAD kinase; Provisional


:

Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 551.86  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   1 MDSPFKTVALIGKPHHEGANQTLTGLYQYLTSRGFRVLLESRVAHTLGLLGENVMDLVQLGEQADLAIVVGGDGNMLGAA 80
Cdd:PRK03378   1 MNNHFKCIGIVGHPRHPTALTTHEMLYHWLTSKGYEVIVEQQIAHELQLKNVKTGTLAEIGQQADLAIVVGGDGNMLGAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  81 RVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMI 160
Cdd:PRK03378  81 RVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHGQQKRISTAINEVVLHPGKVAHMI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 161 EFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSPdnQDD 240
Cdd:PRK03378 161 EFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSSSTIRLKFSP--NRS 238

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 498359488 241 AMQVSCDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGWGSKLF 294
Cdd:PRK03378 239 DLEISCDSQIALPIQPGEEVLIRRSDYHLNLIHPKDYSYFNTLRTKLGWSKKLF 292
 
Name Accession Description Interval E-value
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-294 0e+00

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 551.86  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   1 MDSPFKTVALIGKPHHEGANQTLTGLYQYLTSRGFRVLLESRVAHTLGLLGENVMDLVQLGEQADLAIVVGGDGNMLGAA 80
Cdd:PRK03378   1 MNNHFKCIGIVGHPRHPTALTTHEMLYHWLTSKGYEVIVEQQIAHELQLKNVKTGTLAEIGQQADLAIVVGGDGNMLGAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  81 RVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMI 160
Cdd:PRK03378  81 RVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHGQQKRISTAINEVVLHPGKVAHMI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 161 EFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSPdnQDD 240
Cdd:PRK03378 161 EFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSSSTIRLKFSP--NRS 238

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 498359488 241 AMQVSCDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGWGSKLF 294
Cdd:PRK03378 239 DLEISCDSQIALPIQPGEEVLIRRSDYHLNLIHPKDYSYFNTLRTKLGWSKKLF 292
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
5-292 9.10e-135

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 382.56  E-value: 9.10e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   5 FKTVALIGKPHHEGANQTLTGLYQYLTSRGFRVLLESRVAhtlgllgENVMDLVQLGEQADLAIVVGGDGNMLGAARVLS 84
Cdd:COG0061    1 MKRIAIVAKPGKPEALEAAEELAELLEERGIEVVLDEDTA-------VPGVPLEELGEEADLVIVLGGDGTLLRAARLLA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  85 RFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMIEFEV 164
Cdd:COG0061   74 PLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRDGEVVHEALALNEVVVLRGSIARMIELEV 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 165 YIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSPDNQDdaMQV 244
Cdd:COG0061  154 YIDGEFLEEFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTLSSRPLVLPDDSEIEIEVLEDSRP--AVL 231

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 498359488 245 SCDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGWGSK 292
Cdd:COG0061  232 VADGQEVRDLEPGDRVEIRRSPKPVRLLRLKDHSFFERLREKLGWGGD 279
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 146-273 5.81e-47

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 153.61  E-value: 5.81e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  146 VNEAVLHPGKIAHMIEFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDA 225
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 498359488  226 DSEVRLLVSPDNQddaMQVSCDGQVTLAVHPGDEILIKKSSHKLHLVH 273
Cdd:pfam20143  81 SSKLRIRVLSRAE---ALLVDDGDPELDISPGDRVRVRKSYYKAKFIR 125
 
Name Accession Description Interval E-value
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-294 0e+00

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 551.86  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   1 MDSPFKTVALIGKPHHEGANQTLTGLYQYLTSRGFRVLLESRVAHTLGLLGENVMDLVQLGEQADLAIVVGGDGNMLGAA 80
Cdd:PRK03378   1 MNNHFKCIGIVGHPRHPTALTTHEMLYHWLTSKGYEVIVEQQIAHELQLKNVKTGTLAEIGQQADLAIVVGGDGNMLGAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  81 RVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMI 160
Cdd:PRK03378  81 RVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHGQQKRISTAINEVVLHPGKVAHMI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 161 EFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSPdnQDD 240
Cdd:PRK03378 161 EFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVIDSSSTIRLKFSP--NRS 238

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 498359488 241 AMQVSCDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGWGSKLF 294
Cdd:PRK03378 239 DLEISCDSQIALPIQPGEEVLIRRSDYHLNLIHPKDYSYFNTLRTKLGWSKKLF 292
ppnK PRK01231
NAD(+) kinase;
4-293 6.11e-146

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 411.66  E-value: 6.11e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   4 PFKTVALIGKPHHEGANQTLTGLYQYLTSRGFRVLLESRVAHTLGLLGENVMDLVQLGEQADLAIVVGGDGNMLGAARVL 83
Cdd:PRK01231   3 SFRNIGLIGRLGSSSVVETLRRLKDFLLDRGLEVILDEETAEVLPGHGLQTVSRKLLGEVCDLVIVVGGDGSLLGAARAL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  84 SRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMIEFE 163
Cdd:PRK01231  83 ARHNVPVLGINRGRLGFLTDIRPDELEFKLAEVLDGHYQEEERFLLEAEVRRGGEVIGQGDALNDVVLHPGKSTRMIEFE 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 164 VYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSPDNQDDAMq 243
Cdd:PRK01231 163 LYIDGQFVCSQRSDGLIVSTPTGSTAYALSGGGPIMHPKLDAIVLVPMFPHTLSSRPIVVDGNSEIKIVISKDNRTYPR- 241

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 498359488 244 VSCDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGWGSKL 293
Cdd:PRK01231 242 VSCDGQNSVTLAPGDTVTIRKKPQKLRLIHPLDYNYYETCRTKLGWGSRL 291
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
5-292 9.10e-135

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 382.56  E-value: 9.10e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   5 FKTVALIGKPHHEGANQTLTGLYQYLTSRGFRVLLESRVAhtlgllgENVMDLVQLGEQADLAIVVGGDGNMLGAARVLS 84
Cdd:COG0061    1 MKRIAIVAKPGKPEALEAAEELAELLEERGIEVVLDEDTA-------VPGVPLEELGEEADLVIVLGGDGTLLRAARLLA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  85 RFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMIEFEV 164
Cdd:COG0061   74 PLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRDGEVVHEALALNEVVVLRGSIARMIELEV 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 165 YIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSPDNQDdaMQV 244
Cdd:COG0061  154 YIDGEFLEEFRGDGLIVSTPTGSTAYNLSAGGPIVHPGLDALVLTPIAPHTLSSRPLVLPDDSEIEIEVLEDSRP--AVL 231

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 498359488 245 SCDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGWGSK 292
Cdd:COG0061  232 VADGQEVRDLEPGDRVEIRRSPKPVRLLRLKDHSFFERLREKLGWGGD 279
ppnK PRK02231
NAD(+) kinase;
26-293 1.02e-125

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 359.50  E-value: 1.02e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  26 LYQYLTSRGFRVLLESRVAHTLGLLGENVMDLVQLGEQADLAIVVGGDGNMLGAARVLSRFDVAVIGVNRGNLGFLTDLS 105
Cdd:PRK02231   5 LFHWLKERGYQVLVEKEIAEQLNLPENHLASLEEIGQRAQLAIVIGGDGNMLGRARVLAKYDIPLIGINRGNLGFLTDID 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 106 PQDYLLPLEQVLS-GHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMIEFEVYIDGSFMYSQRSDGIIVATP 184
Cdd:PRK02231  85 PKNAYEQLEACLErGEFFVEERFLLEAKIERNGKIIATSNALNEVVIHPAKIAHMIDFHVYIDDKFAFSQRSDGLIISTP 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 185 TGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSPDNQDDaMQVSCDGQVTLAVHPGDEILIKK 264
Cdd:PRK02231 165 TGSTAYSLSAGGPILTPNLNAIALVPMFPHTLSSRPLVIDGDSKISLRFAEYNTPQ-LEVSCDSQIALPFTPDDRVHVQK 243

                        250       260
                 ....*....|....*....|....*....
gi 498359488 265 SSHKLHLVHPLDYSYFHVLRNKLGWGSKL 293
Cdd:PRK02231 244 SPDKLRLLHLKNYNYYNVLSSKLGWLKKL 272
ppnK PRK02155
NAD kinase;
1-289 4.53e-120

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 345.77  E-value: 4.53e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   1 MDSPFKTVALIGKPHHEGANQTLTGLYQYLTSRGFRVLLESRVAHTLGLLGENVMDLVQLGEQADLAIVVGGDGNMLGAA 80
Cdd:PRK02155   1 MKSQFKTVALIGRYQTPGIAEPLESLAAFLAKRGFEVVFEADTARNIGLTGYPALTPEEIGARADLAVVLGGDGTMLGIG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  81 RVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMI 160
Cdd:PRK02155  81 RQLAPYGVPLIGINHGRLGFITDIPLDDMQETLPPMLAGNYEEEERMLLEARVVRDGEPIFHALAFNDVVVNRSGFSGMV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 161 EFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSpdNQDD 240
Cdd:PRK02155 161 ELRVSVDGRFMYNQRSDGLIVATPTGSTAYALSAGGPILHPQLPGWVLVPIAPHTLSNRPIVLPDDSEVAIQIV--GGRD 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 498359488 241 AmQVSCDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGW 289
Cdd:PRK02155 239 V-SVNFDMQSLTSLELGDRIEVRRSPHTVRFLHPVGYSYYATLRKKLHW 286
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 1-293 6.05e-86

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 259.40  E-value: 6.05e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   1 MDSPFKTVALIGKPHHEGANQTLTGLYQYLTSRGFRVLLESRVAHTLGLL-----GENVMDLVQLGEQADLAIVVGGDGN 75
Cdd:PRK04539   1 MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGIKEGCIYtqdtvGCHIVNKTELGQYCDLVAVLGGDGT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  76 MLGAARVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGK 155
Cdd:PRK04539  81 FLSVAREIAPRAVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIREGKTAERALALNDAVLSRGG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 156 IAHMIEFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSp 235
Cdd:PRK04539 161 AGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILVT- 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 498359488 236 dnQDDAMQVSCDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGWGSKL 293
Cdd:PRK04539 240 --QGGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHPTDYQYFKTLRQKLHWGEQL 295
ppnK PRK02649
NAD(+) kinase;
12-290 1.20e-59

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 192.12  E-value: 1.20e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  12 GKPHhegANQTLTGLYQYLTSRGFRVLLESRVAhtlGLLGENVMD----------LVQLG--EQADLAIVVGGDGNMLGA 79
Cdd:PRK02649  11 GKPL---AVRTAEELQDKLEAAGWEVVRASSSG---GILGYANPDqpvchtgidqLVPPGfdSSMKFAIVLGGDGTVLSA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  80 ARVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHM 159
Cdd:PRK02649  85 ARQLAPCGIPLLTINTGHLGFLTEAYLNQLDEAIDQVLAGQYTIEERTMLTVSVMRGDQLRWEALSLNEMVLHREPLTSM 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 160 IEFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLdADSEvRLLVSPDNQD 239
Cdd:PRK02649 165 CHFEIAIGRHAPVDIAADGVILSTPTGSTAYSLSAGGPVITPDVPVLQLTPICPHSLASRALVF-SDSE-PVTVFPATPE 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 498359488 240 DAMQVsCDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGWG 290
Cdd:PRK02649 243 RLVMV-VDGNAGCYVWPEDRVLIRRSPYPVRFIRLQDPEFFRVLREKLGWG 292
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 8-290 8.64e-59

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 189.75  E-value: 8.64e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   8 VALIGKPHHEGANQTLTGLYQYLTSRGFRVLLESRVAHTLGLLG------ENVMDLVQLGEQADLAIVVGGDGNMLGAAR 81
Cdd:PRK01911   3 IAIFGQTYQESASPYIQELFDELEERGAEVLIEEKFLDFLKQDLkfhpsyDTFSDNEELDGSADMVISIGGDGTFLRTAT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  82 VLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVyRHGERKSSNLAVNEAVLHPGKIAHMIE 161
Cdd:PRK01911  83 YVGNSNIPILGINTGRLGFLATVSKEEIEETIDELLNGDYTIEERSLLQLES-NPKLFGELNFALNEIAILKRDTSSMIT 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 162 FEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSpdNQDDA 241
Cdd:PRK01911 162 VHTYLNGEYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPHNLNVRPLVIPDDTEITLEVE--SRSDN 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 498359488 242 MQVSCDGQVTlAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGWG 290
Cdd:PRK01911 240 FLVSLDSRSE-TVDNGTELTIKKADFTIKLVELNNHSFLKTLRNKLLWG 287
pnk PRK14077
NAD(+) kinase;
6-290 2.03e-52

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 173.04  E-value: 2.03e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   6 KTVALIGKPHHEgANQTLTGLYQYLTSRGFRVLLESRVAHTLGLLGenvMDLVQLGEQADLAIVVGGDGNMLGAARVLSR 85
Cdd:PRK14077  11 KKIGLVTRPNVS-LDKEILKLQKILSIYKVEILLEKESAEILDLPG---YGLDELFKISDFLISLGGDGTLISLCRKAAE 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  86 FDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMIEFEVY 165
Cdd:PRK14077  87 YDKFVLGIHAGHLGFLTDITVDEAEKFFQAFFQGEFEIEKPYMLSVFLEKKQGKILEKLAFNDVVISKNNQASMAHIEAF 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 166 IDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSpdnqDDAMQVs 245
Cdd:PRK14077 167 LNEKYFNEYFGDGVIVATPAGSTAYNMSANGPIIYPLSQVFILTPVCSHSLTQRPIVLPKGFEVEFKTK----SDCILC- 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 498359488 246 CDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYSYFHVLRNKLGWG 290
Cdd:PRK14077 242 IDGQDRYKMNDFKSIKVGLSDKNVALIRHKNRDYFQILKEKLHWG 286
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
29-280 3.04e-52

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 179.54  E-value: 3.04e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  29 YLTSRGFRVLLESRVAHTL-GLLGENVMDLVQLgEQADLAIVVGGDGNMLGAARVLSRFDVAVIGVNRGNLGFLTDLSPQ 107
Cdd:PRK14076 314 YLDSKGIPYELESFLYNKLkNRLNEECNLIDDI-EEISHIISIGGDGTVLRASKLVNGEEIPIICINMGTVGFLTEFSKE 392

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 108 DYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMIEFEVYIDGSFMYSQRSDGIIVATPTGS 187
Cdd:PRK14076 393 EIFKAIDSIISGEYEIEKRTKLSGFILKDGHQNILPSALNEVVITTKNPAKMLHFEVYVNGELVEEVRADGIIISTPTGS 472

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 188 TAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSpdnQDDAMQVsCDGQVTLAVHPGDEILIKKSSh 267
Cdd:PRK14076 473 TAYSLSAGGPIVEPTVDGFIIVPICPFKLSSRPLVVSANSEIKIKLL---KKSALVV-IDGSIEFEAKKGDEIIFRKSD- 547

                        250
                 ....*....|...
gi 498359488 268 klhlvhplDYSYF 280
Cdd:PRK14076 548 --------SYAYF 552
ppnK PRK03708
NAD(+) kinase;
26-272 4.07e-52

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 172.20  E-value: 4.07e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  26 LYQYLTSRGFRVLLESRVAHTLGLLGEN-VMDLVQLgeQADLAIVVGGDGNMLGAARvLSRFDVAVIGVNRGNLGFLTDL 104
Cdd:PRK03708  21 VYDFLKVSGYEVVVDSETYEHLPEFSEEdVLPLEEM--DVDFIIAIGGDGTILRIEH-KTKKDIPILGINMGTLGFLTEV 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 105 SPQDYLLPLEQVLSGHFKSEHRFLLEaaVYRHGERKSSnlAVNEAVLHPGKIAHMIEFEVYIDGSFMYSQRSDGIIVATP 184
Cdd:PRK03708  98 EPEETFFALSRLLEGDYFIDERIKLR--VYINGENVPD--ALNEVVILTGIPGKIIHLKYYVDGELADEVRADGLIISTP 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 185 TGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADS--EVRLLVSpdnqDDAMQVSCDGQVTLAVHPGDEILI 262
Cdd:PRK03708 174 TGSTAYAMSAGGPFVDPRLDAILIAPLCPFKLSSRPMVVPSSSriDVKLLRT----GREIILVIDGQYYEELPPDTEITI 249

                        250
                 ....*....|
gi 498359488 263 KKSSHKLHLV 272
Cdd:PRK03708 250 KKSPRKTKFV 259
ppnK PRK02645
NAD(+) kinase;
57-289 3.19e-49

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 165.47  E-value: 3.19e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  57 LVQLGEQADLAIVVGGDGNMLGAARVLSRFDVAVIGVN-RGNLGFLTDlsPQDYLL---PLEQVLSGHFKSEHRFLLEAA 132
Cdd:PRK02645  51 LASASELIDLAIVLGGDGTVLAAARHLAPHDIPILSVNvGGHLGFLTH--PRDLLQdesVWDRLQEDRYAIERRMMLQAR 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 133 VY---RHGERKSSN--LAVNEAVLHPGKIAHMI--EFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNA 205
Cdd:PRK02645 129 VFegdRSNEEPVSEsyYALNDFYLKPASEDRSPtcILELEIDGEVVDQYQGDGLIVSTPTGSTAYTMAAGGPILHPGIDA 208

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 206 ITLVPMFPHTLSSRPIVLDADSevRLLVSP-DNQDDAMQVSCDGQVTLAVHPGDEILIKKS-SHKLHLVHPLDYSYFHVL 283
Cdd:PRK02645 209 IIVTPICPMSLSSRPIVIPPGS--RVVIWPlGDYDLNIKLWKDGVLATSIWPGQRCVIQKArHPAKFIILEESYSYYRTL 286


                 ....*.
gi 498359488 284 RNKLGW 289
Cdd:PRK02645 287 REKLHW 292
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 146-273 5.81e-47

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 153.61  E-value: 5.81e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  146 VNEAVLHPGKIAHMIEFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDA 225
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 498359488  226 DSEVRLLVSPDNQddaMQVSCDGQVTLAVHPGDEILIKKSSHKLHLVH 273
Cdd:pfam20143  81 SSKLRIRVLSRAE---ALLVDDGDPELDISPGDRVRVRKSYYKAKFIR 125
ppnK PRK01185
NAD(+) kinase;
37-287 2.34e-44

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 151.89  E-value: 2.34e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  37 VLLESRVAHTLGLLGENVMDLvqlgeQADLAIVVGGDGNMLgaaRVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQV 116
Cdd:PRK01185  31 IIYEMEAAKALGMDGLDIEEI-----NADVIITIGGDGTIL---RTLQRAKGPILGINMGGLGFLTEIEIDEVGSAIKKL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 117 LSGHFKSEHRFLLEaaVYRHGERksSNLAVNEAVLHPGKIAHMIEFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGG 196
Cdd:PRK01185 103 IRGEYFIDERMKLK--VYINGER--LEDCTNEAVIHTDRIAKIRQFKIYYDGHFLDTFKADGVIVATPTGSTSYSSSAGG 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 197 AILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSpDNQDDAMQVscDGQVTLAVHPGDEILIKKSSHKLHLVHpLD 276
Cdd:PRK01185 179 PILLPNLEGMVISYIAPYSSRPKSVVVPSESTVEIKIA-GDQSSLLIL--DGQYEYKISKGDTVEISKSENYARFIS-FR 254

                        250
                 ....*....|.
gi 498359488 277 YSYFHVLRNKL 287
Cdd:PRK01185 255 ESPYDRIREKL 265
pnk PRK14075
NAD(+) kinase;
64-293 1.26e-42

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 146.80  E-value: 1.26e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  64 ADLAIVVGGDGNMLGAARvlsRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVyrhgeRKSSN 143
Cdd:PRK14075  42 ADLIIVVGGDGTVLKAAK---KVGTPLVGFKAGRLGFLSSYTLEEIDRFLEDLKNWNFREEKRWFLKIES-----ELGNH 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 144 LAVNEAVLHPGKIAHMIEFEVYID--GSFMYsqRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPI 221
Cdd:PRK14075 114 LALNDVTLERDPSQKMVEIEVSFEdhSSMWF--FADGVVISTPTGSTAYSLSLGGPIILPNCEVFEITPIAPQFLATRSI 191

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 498359488 222 VLdadsevrllvsPDNQDdaMQVSCDGQVTLAVHpGD------EILIKKSSHKLHLVHPLDYSYFHVLRNKLGWGSKL 293
Cdd:PRK14075 192 VI-----------PSNEK--VTVESQRDINLIVD-GVlvgktnRITVKKSRRYVRILRPKDYDFVTVIKEKLGYGRRI 255
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 28-272 3.63e-42

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 146.99  E-value: 3.63e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  28 QYLTSRGFRVLLESRVAHTLGLLGENVMDLVQLG---------EQADLAIVVGGDGNMLGAARVLSRFDVAVIGVNRGNL 98
Cdd:PRK03372  28 KQLGDAGIGVRVLDAEAVDLGATHPAPDDFRAMEvvdadpdaaDGCELVLVLGGDGTILRAAELARAADVPVLGVNLGHV 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  99 GFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSNLAVNEAVLHPGKIAHMIEFEVYIDGSFMYSQRSDG 178
Cdd:PRK03372 108 GFLAEAEAEDLDEAVERVVDRDYRVEERMTLDVTVRVGGEIVWRGWALNEASLEKADREGMLEVVLEVDGRPVSSFGCDG 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 179 IIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLDADSEVRLLVSPDNqDDAMqVSCDGQVTLAVHPGD 258
Cdd:PRK03372 188 VLVSTPTGSTAYAFSAGGPVVWPDLEALLVVPLNAHALFARPLVVSPTSTVAVEILADT-SDAV-LWCDGRRSVDLPPGA 265

                        250
                 ....*....|....
gi 498359488 259 EILIKKSSHKLHLV 272
Cdd:PRK03372 266 RVEVRRGATPVRLA 279
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 2-265 6.03e-33

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 126.49  E-value: 6.03e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488   2 DSPFKTVALIGKPHHEGANQTLTGLYQYL-TSRGFRVLLESRVAHTLglLGENVM-----------DLVQLGEQADLAIV 69
Cdd:PLN02935 191 ESDPQTVLIITKPNSTSVRVLCAEMVRWLrEQKGLNIYVEPRVKKEL--LSESSYfnfvqtwedekEILLLHTKVDLVIT 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  70 VGGDGNMLGAARVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGERKSSN-----L 144
Cdd:PLN02935 269 LGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHIIRDAAKNEYEteepiL 348

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 145 AVNEAVLHPGKIAHMIEFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSRPIVLD 224
Cdd:PLN02935 349 VLNEVTIDRGISSFLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPGILFTPICPHSLSFRPLILP 428

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 498359488 225 ADSEVRLLVsPDNQDDAMQVSCDGQVTLAVHPGDEILIKKS 265
Cdd:PLN02935 429 EYVTIRVQV-PFNSRGQAWASFDGKDRKQLSAGDALVCSMA 468
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 62-272 2.61e-31

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 117.23  E-value: 2.61e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  62 EQADLAIVVGGDGNMLGA-ARVLSRFD-VAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEHRFLLEAAVYRHGER 139
Cdd:PRK04885  34 KNPDIVISVGGDGTLLSAfHRYENQLDkVRFVGVHTGHLGFYTDWRPFEVDKLVIALAKDPGQVVSYPLLEVKITYEDGE 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 140 KSSNLAVNEAVLHpgKIAHMIEFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPM-------F 212
Cdd:PRK04885 114 KEKYLALNEATIK--RIEGTLVADVYINGVLFERFRGDGLCVSTPTGSTAYNKSLGGAVLHPSIEALQLTEIasinnrvF 191

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 213 pHTLSSrPIVLDADSEVRLlvSPDNQDDAmQVSCDgQVTLAVHPGDEILIKKSSHKLHLV 272
Cdd:PRK04885 192 -RTLGS-PLILPKHHTITL--KPVNDDDY-QITVD-HLTIKHKNVKSIEYRVANEKIRFA 245
PLN02727 PLN02727
NAD kinase
 56-293 1.92e-29

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 117.68  E-value: 1.92e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  56 DLVQLGEQADLAIVVGGDGNMLGAARVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSGHFKSEH-----RFLLE 130
Cdd:PLN02727 736 DTSDLHERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVIHGNNTLDGvyitlRMRLR 815

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 131 AAVYRHGERKSSNL--AVNEAVLHPGKIAHMIEFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITL 208
Cdd:PLN02727 816 CEIFRNGKAMPGKVfdVLNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYSTAAGGSMVHPNVPCMLF 895

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 209 VPMFPHTLSSRPIVLDADSEVRLLVSPDNQDDAMqVSCDGQVTLAVHPGDEILIKKSSHKLHLVHPLDYS--YFHVLRNK 286
Cdd:PLN02727 896 TPICPHSLSFRPVILPDSARLELKIPDDARSNAW-VSFDGKRRQQLSRGDSVRISMSQHPLPTVNKSDQTgdWFRSLIRC 974


                 ....*..
gi 498359488 287 LGWGSKL 293
Cdd:PLN02727 975 LNWNERL 981
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 62-199 1.75e-20

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 87.95  E-value: 1.75e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  62 EQADLAIVVGGDGNMLGAARVLSRFDVAVIGVNRGNLGFL-TDLSPQDyllpLEQVLSGHFKSEHRFLLEAAVYRHGERK 140
Cdd:PRK04761  24 EEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLmNEYSEDD----LLERIAAAEPTVLHPLRMTATDVSGEVH 99

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 498359488 141 SSnLAVNE-AVLHPGKIAhmIEFEVYIDGSFMYSQ-RSDGIIVATPTGSTAYSLSAGGAIL 199
Cdd:PRK04761 100 EA-LAINEvSLFRQTRQA--AKLRISIDGKVRMEElVCDGVLVATPAGSTAYNLSAHGPIL 157
ppnK PRK00561
NAD(+) kinase;
64-250 3.61e-18

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 81.85  E-value: 3.61e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  64 ADLAIVVGGDGNMLGAARVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVLSgHFKSEHRFLLEAAVYRHGERKSSN 143
Cdd:PRK00561  34 ADYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGFYTSFNETDLDQNFANKLD-QLKFTQIDLLEVQIDDQIHLVLNE 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 144 LAVNEAVLHPgkiahmieFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGGAILTPKLNAITLVPMFPHTLSSR---- 219
Cdd:PRK00561 113 LAVYTNTAYP--------INIFIDNEFWEKYRGSGLLIGPRTGSTALAKSAKGAVIFPRIDVIQIIELNPLLHPNQttiq 184

                        170       180       190
                 ....*....|....*....|....*....|...
gi 498359488 220 -PIVLDADSEVRLLVSPD-NQDDAMQVSCDGQV 250
Cdd:PRK00561 185 sPIILPIDTKVEFEIKKAfDHDQFPRFYADGAK 217
ppnK PRK03501
NAD kinase;
50-287 2.66e-17

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 79.64  E-value: 2.66e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  50 LGENVMDLVQLGEQADLAIV-----------VGGDGNMLGAARVLS-RFDVAVIGVNR-GNLGFLTDLSPQDYLLPLEQV 116
Cdd:PRK03501  15 LVEKVKPLKKIAEEYGFTVVdhpknaniivsIGGDGTFLQAVRKTGfREDCLYAGISTkDQLGFYCDFHIDDLDKMIQAI 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 117 LSGHFKSEHRFLLEAAVyrhgERKSSNLAVNEAVLHPGKIAHMIeFEVYIDGSFMYSQRSDGIIVATPTGSTAYSLSAGG 196
Cdd:PRK03501  95 TKEEIEVRKYPTIEVTV----DGSTSFYCLNEFSIRSSIIKTFV-IDVYIDDLHFETFRGDGMVVSTPTGSTAYNKSVRG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 197 AILTPKLNAITLVPMFP------HTLSSrPIVLDADSEVRLLVSPDNQDDAMqVSCDGQvTLAVHPGDEILIKKSSHKLH 270
Cdd:PRK03501 170 AVVDPLIPCFQVSELASlnnntyRTLGS-PFILSHERKLTLKIVQDGNDYPI-IGMDNE-ALSIKHVEKIDIRLSDKQIK 246

                        250
                 ....*....|....*...
gi 498359488 271 LVHPLDYSYFH-VLRNKL 287
Cdd:PRK03501 247 TVKLKDNSFWEkVKRTFL 264
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 8-117 7.06e-17

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 75.09  E-value: 7.06e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488    8 VALIGKPHHEGANQTLTGLYQYL-TSRGFRVLLESRVAHTLGLLGENVMDLV----------------QLGEQADLAIVV 70
Cdd:pfam01513   1 VGIVVNPDKKEALERAREVARWLlDRLGITVTVEEKMGESLAFAAGDRPEVIgclkkvvddtrratraFADAGVDLIIVL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 498359488   71 GGDGNMLGAARVLSRFDVAVIGVNRGNLGFLTDLSPQDYLLPLEQVL 117
Cdd:pfam01513  81 GGDGTALRAARLLQKAVIPILGVNTGVLGFLTEFEPEAAFELLERLL 127
PLN02929 PLN02929
NADH kinase
 64-262 5.19e-06

NADH kinase


Pssm-ID: 215502 [Multi-domain]  Cd Length: 301  Bit Score: 46.95  E-value: 5.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488  64 ADLAIVVGGDGNMLGAARVLsRFDVAVIGVN------------------RGNLGFLTDLSPQDYLLPLEQVLSGHFKSEH 125
Cdd:PLN02929  65 VDLVVAVGGDGTLLQASHFL-DDSIPVLGVNsdptqkdeveeysdefdaRRSTGHLCAATAEDFEQVLDDVLFGRLKPTE 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359488 126 RFLLEAAVyrhGERKSSNLAVNEAVL-HPGKIA-HMIEFEVYIDG---SFMYSQRSDGIIVATPTGSTAYSLSAGG---A 197
Cdd:PLN02929 144 LSRISTVV---NGTLLETPALNDVLIaHPSPAAvSRFSFRVGRQGgssGPLINVRSSGLRVSTAAGSTAAMLSAGGfpmP 220

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 498359488 198 ILTPKLNAITLVPMFPHtlsSRPIVLD---ADSEVRLLVSPDNQDDAMQVscDG-QVTLAVHPGDEILI 262
Cdd:PLN02929 221 LLSRDLQYMVREPISPG---HPPKSLMhgfYKPGQHMQVRWNSRKGTIYI--DGsHVMHSIKLGDTIEI 284
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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