|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-1041 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1756.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 1 MARFFIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSA 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 81 QSDSSGNVSVTLTFKPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQGVRVQKTSSSFLMVAAFISTDGAMTNDDLADYVVA 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 161 NIKEPLSRLDGVGDITLFGSQYSMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAFGKLGGTPAVSDQQFTATIMGQTRL 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 241 STVEEFNNILLRVNQDGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPAN 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 321 MEIVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 401 AIGLLVDDAIVVVENVERLMSEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFSLTIVSAMVL 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 481 SVLVALILTPALCATLLKPMKHGEFGAQR-GFFGWFNRFFDTNANRYQNGVRKVIKQGTRYGIIYLAMLAVLAVLFMRMP 559
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPIEKGEHHEKKgGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 560 TSFLPEEDQGVIMSMVQLPVGATKERTEVVLGEMRDYFLENEKENVDSVLTVAGFSFAGSGQNSGMAFIKLKDWSERKGE 639
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 640 ERSANAIIGRAMGFLFSIKEAQVFAFNLPPIPELGTATGFDFFLQDRGGLGHEKLMQARNQLLGMASQDPNLVRVRPNGM 719
Cdd:TIGR00915 641 ENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPALTRVRPNGL 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 720 EDTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVYLQADAPFRMNPEDLKLWYVRNSAGQMVPF 799
Cdd:TIGR00915 721 EDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVPF 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 800 SAFASTEWSFGSPRLERYNGVSAMEIVGEAAPGKSTGDAMAAIEEMVKQLPEGIGIEWTGLSFQERQAGSQAPALYAISL 879
Cdd:TIGR00915 801 SAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALSL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 880 LVVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKELHDKGMRLGD 959
Cdd:TIGR00915 881 LVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVE 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 960 AVVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLVMRYFTERKHAGEE 1039
Cdd:TIGR00915 961 AALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEKEM 1040
|
..
gi 498359555 1040 SV 1041
Cdd:TIGR00915 1041 SV 1042
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-1040 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 1675.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 1 MARFFIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSA 80
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 81 QSDSSGNVSVTLTFKPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQGVRVQKTSSSFLMVAAFISTDGAMTNDDLADYVVA 160
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 161 NIKEPLSRLDGVGDITLFGSQYSMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAFGKLGGTPAVSDQQFTATIMGQTRL 240
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 241 STVEEFNNILLRVNQDGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPAN 320
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 321 MEIVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLVL 400
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 401 AIGLLVDDAIVVVENVERLMSEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFSLTIVSAMVL 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 481 SVLVALILTPALCATLLKPMKHGEFGAQR-GFFGWFNRFFDTNANRYQNGVRKVIKQGTRYGIIYLAMLAVLAVLFMRMP 559
Cdd:PRK15127 481 SVLVALILTPALCATMLKPIAKGDHGEGKkGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 560 TSFLPEEDQGVIMSMVQLPVGATKERTEVVLGEMRDYFLENEKENVDSVLTVAGFSFAGSGQNSGMAFIKLKDWSERKGE 639
Cdd:PRK15127 561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 640 ERSANAIIGRAMGFLFSIKEAQVFAFNLPPIPELGTATGFDFFLQDRGGLGHEKLMQARNQLLGMASQDPN-LVRVRPNG 718
Cdd:PRK15127 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDmLVGVRPNG 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 719 MEDTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVYLQADAPFRMNPEDLKLWYVRNSAGQMVP 798
Cdd:PRK15127 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 799 FSAFASTEWSFGSPRLERYNGVSAMEIVGEAAPGKSTGDAMAAIEEMVKQLPEGIGIEWTGLSFQERQAGSQAPALYAIS 878
Cdd:PRK15127 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQERLSGNQAPALYAIS 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 879 LLVVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKELHDK-GMRL 957
Cdd:PRK15127 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKeGKGL 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 958 GDAVVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLVMRYFTERKHAG 1037
Cdd:PRK15127 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
|
...
gi 498359555 1038 EES 1040
Cdd:PRK15127 1041 EHS 1043
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
1-1030 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 1607.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 1 MARFFIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSA 80
Cdd:PRK10555 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 81 QSDSSGNVSVTLTFKPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQGVRVQKTSSSFLMVAAFISTDGAMTNDDLADYVVA 160
Cdd:PRK10555 81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 161 NIKEPLSRLDGVGDITLFGSQYSMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAFGKLGGTPAVSDQQFTATIMGQTRL 240
Cdd:PRK10555 161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 241 STVEEFNNILLRVNQDGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPAN 320
Cdd:PRK10555 241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 321 MEIVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLVL 400
Cdd:PRK10555 321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 401 AIGLLVDDAIVVVENVERLMSEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFSLTIVSAMVL 480
Cdd:PRK10555 401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 481 SVLVALILTPALCATLLKPMKHGEFGAQRGFFGWFNRFFDTNANRYQNGVRKVIKQGTRYGIIYLAMLAVLAVLFMRMPT 560
Cdd:PRK10555 481 SVLVAMILTPALCATLLKPLKKGEHHGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPT 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 561 SFLPEEDQGVIMSMVQLPVGATKERTEVVLGEMRDYFLENEKENVDSVLTVAGFSFAGSGQNSGMAFIKLKDWSERKGEE 640
Cdd:PRK10555 561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSKT 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 641 RSANAIIGRAMGFLFSIKEAQVFAFNLPPIPELGTATGFDFFLQDRGGLGHEKLMQARNQLLGMASQDPNLVRVRPNGME 720
Cdd:PRK10555 641 GTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNPELTRVRHNGLD 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 721 DTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVYLQADAPFRMNPEDLKLWYVRNSAGQMVPFS 800
Cdd:PRK10555 721 DSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 801 AFASTEWSFGSPRLERYNGVSAMEIVGEAAPGKSTGDAMAAIEEMVKQLPEGIGIEWTGLSFQERQAGSQAPALYAISLL 880
Cdd:PRK10555 801 AFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 881 VVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKELHDKGMRLGDA 960
Cdd:PRK10555 881 VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA 960
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 961 VVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLVMRYF 1030
Cdd:PRK10555 961 TLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVLVRRRF 1030
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1026 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1354.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 1 MARFFIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSA 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 81 QSdSSGNVSVTLTFKPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQGVRVQKTSSSFLMVAAFISTDGAMTNDDLADYVVA 160
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 161 NIKEPLSRLDGVGDITLFG-SQYSMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAFGKLggtpavSDQQFTATIMGQTR 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGgSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 240 LSTVEEFNNILLRvNQDGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPA 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 320 NMEIVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 400 LAIGLLVDDAIVVVENVERLMSEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFSLTIVSAMV 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 480 LSVLVALILTPALCATLLKPMKHGEfgaQRGFFGWFNRFFDTNANRYQNGVRKVIKQGTRYGIIYLAMLAVLAVLFMRMP 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPK---HGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIP 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 560 TSFLPEEDQGVIMSMVQLPVGATKERTEVVLGEMRDYFLenEKENVDSVLTVAGFSFAG--SGQNSGMAFIKLKDWSERK 637
Cdd:pfam00873 550 TEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILK--EKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKERP 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 638 GEERSANAIIGRAMGFLFSIKEAQVFAFNLPPIPELGTATGFDFFLQD-RGGLGHEKLMQARNQLLGMASQDPNLVRVRP 716
Cdd:pfam00873 628 GPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPGLSDVRS 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 717 NGMEDTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVYLQADAPFRMNPEDLKLWYVRNSAGQM 796
Cdd:pfam00873 708 DGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKM 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 797 VPFSAFASTEWSFGSPRLERYNGVSAMEIVGEAAPGKSTGDAMAAIEEMVKQ--LPEGIGIEWTGLSFQERQAGSQAPAL 874
Cdd:pfam00873 788 IPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLPIL 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 875 YAISLLVVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKELHD-K 953
Cdd:pfam00873 868 IALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREqE 947
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 498359555 954 GMRLGDAVVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLV 1026
Cdd:pfam00873 948 GKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLF 1020
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1028 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1265.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 1 MARFFIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSA 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 81 QSdSSGNVSVTLTFKPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQGVRVQKTSSSFLMVAAFISTDgaMTNDDLADYVVA 160
Cdd:COG0841 83 TS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 161 NIKEPLSRLDGVGDITLFGS-QYSMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAFGKLGGtpavsdQQFTATIMGQTR 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 240 LSTVEEFNNILLRVNqDGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPA 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 320 NMEIVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 400 LAIGLLVDDAIVVVENVERLMsEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFSLTIVSAMV 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 480 LSVLVALILTPALCATLLKPMKHGEfgaQRGFFGWFNRFFDTNANRYQNGVRKVIKQGTRYGIIYLAMLAVLAVLFMRMP 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLKPHPKGK---KGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLP 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 560 TSFLPEEDQGVIMSMVQLPVGATKERTEVVLGEMRDYFLENEkeNVDSVLTVAGFSFAGSGQNSGMAFIKLKDWSERKge 639
Cdd:COG0841 549 TEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVP--EVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERD-- 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 640 eRSANAIIGRAMGFLFSIKEAQVFAFNlPPIPELGTATGFDFFLQdrgGLGHEKLMQARNQLLGMASQDPNLVRVRPNGM 719
Cdd:COG0841 625 -RSADEIIARLREKLAKIPGARVFVFQ-PPAGGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDVRSDLQ 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 720 EDTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVYLQADAPFRMNPEDLKLWYVRNSAGQMVPF 799
Cdd:COG0841 700 LGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPL 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 800 SAFASTEWSFGSPRLERYNGVSAMEIVGEAAPGKSTGDAMAAIEEMVKQ--LPEGIGIEWTGLSFQERQAGSQAPALYAI 877
Cdd:COG0841 780 SSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAFLL 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 878 SLLVVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKELHDKGMRL 957
Cdd:COG0841 860 ALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSL 939
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 498359555 958 GDAVVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLVMR 1028
Cdd:COG0841 940 REAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDR 1010
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
1-1035 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 1241.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 1 MARFFIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSA 80
Cdd:PRK09577 1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 81 QSdSSGNVSVTLTFKPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQGVRVQKTSSSFLMVAAFISTDGAMTNDDLADYVVA 160
Cdd:PRK09577 81 TS-SAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 161 NIKEPLSRLDGVGDITLFGSQYSMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAFGKLGGTPAVSDQQFTATIMGQTRL 240
Cdd:PRK09577 160 NVLQALRRVEGVGKVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 241 STVEEFNNILLRVNQDGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPAN 320
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 321 MEIVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLVL 400
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 401 AIGLLVDDAIVVVENVERLMSEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFSLTIVSAMVL 480
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 481 SVLVALILTPALCATLLKPMKHGEFGaQRGFFGWFNRFFDTNANRYQNGVRKVIKQGTRYGIIYLAMLAVLAVLFMRMPT 560
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPVDGDHHE-KRGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPT 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 561 SFLPEEDQGVIMSMVQLPVGATKERTEVVLGEMRDYFLENEKenVDSVLTVAGFSFAGSGQNSGMAFIKLKDWSERKGEE 640
Cdd:PRK09577 559 AFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEP--VAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAAR 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 641 RSANAIIGRAMGFLFSIKEAQVFAFNLPPIPELGTATGFDFFLQDRGGLGHEKLMQARNQLLGMASQDPNLVRVRPNGME 720
Cdd:PRK09577 637 DHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDPALTDLMFAGTQ 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 721 DTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVYLQADAPFRMNPEDLKLWYVRNSAGQMVPFS 800
Cdd:PRK09577 717 DAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVPLA 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 801 AFASTEWSFGSPRLERYNGVSAMEIVGEAAPGKSTGDAMAAIEEMVKQLPEGIGIEWTGLSFQERQAGSQAPALYAISLL 880
Cdd:PRK09577 797 AFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFEERLSGAQAPMLFALSVL 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 881 VVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKELHDKGMRLGDA 960
Cdd:PRK09577 877 VVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQRMSLADA 956
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 498359555 961 VVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLVMRYFTERKH 1035
Cdd:PRK09577 957 ALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGRLFDVGPR 1031
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
3-1028 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 756.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 3 RFFIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSAQS 82
Cdd:NF033617 2 DVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 83 dSSGNVSVTLTFKPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQGV-RVQKTSSSFLMVAAFISTdgAMTNDDLADYVVAN 161
Cdd:NF033617 82 -SLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVyRKANSADTPIMYIGLTSE--EMPRGQLTDYAERV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 162 IKEPLSRLDGVGDITLFGSQY-SMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAFGKLGGTPAVSdqqftaTIMGQTRL 240
Cdd:NF033617 159 LAPKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVS------TVRANDQL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 241 STVEEFNNILLRVNQDGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPAN 320
Cdd:NF033617 233 KTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 321 MEIVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLVL 400
Cdd:NF033617 313 IKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 401 AIGLLVDDAIVVVENVERLMsEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFSLTIVSAMVL 480
Cdd:NF033617 393 AIGLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVII 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 481 SVLVALILTPALCATLLKpmKHGEfgaQRGFFGWFNRFFDTNANRYQNGVRKVIKQGTRYGIIYLAMLAVLAVLFMRMPT 560
Cdd:NF033617 472 SGIVALTLTPMMCSRLLK--ANEK---PGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPK 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 561 SFLPEEDQGVIMSMVQLPVGATKERTEVVLGEMRDYFLEN-EKENVDSVLTVAGFsfagSGQNSGMAFIKLKDWSERkge 639
Cdd:NF033617 547 ELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDpEVQSLTSFNGVGGN----PGDNTGFGIINLKPWDER--- 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 640 ERSANAIIGRAMGFLFSIKEAQVFAFNLPPIPeLGTATGFDFFLQDRGGLGHEKLMQARNQLLGMASQDPNLVRVRPNGM 719
Cdd:NF033617 620 DVSAQEIIDRLRPKLAKVPGMDLFLFPLQDLP-GGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQ 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 720 EDTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVYLQADAPFRMNPEDLKLWYVRNSAGQMVPF 799
Cdd:NF033617 699 DKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPL 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 800 SAFASTEWSFGSPRLERYNGVSAMEIVGEAAPGKSTGDAMAAIEEMVKQ-LPEGIGIEWTGLSFQERQAGSQAPALYAIS 878
Cdd:NF033617 779 STLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKElLPSGISGSFQGAARAFQEEGSSLLFLFLLA 858
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 879 LLVVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKELHD-KGMRL 957
Cdd:NF033617 859 LAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRhQGLSR 938
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 498359555 958 GDAVVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLVMR 1028
Cdd:NF033617 939 REAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
5-1028 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 569.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 5 FIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSaqSDS 84
Cdd:PRK09579 7 FIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMT--SVS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 85 SGNVSVTLTF-KPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQGVRVQKTSSSFLMVAAFIStdGAMTNDDLADYVVANIK 163
Cdd:PRK09579 85 RQNFSIISIYaRIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYS--EEMSNPQITDYLSRVIQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 164 EPLSRLDGVGDITLFGSQ-YSMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAFGKLGGTPAVSdqqftaTIMGQTRLST 242
Cdd:PRK09579 163 PKLATLPGMAEAEILGNQvFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVT------SINASTELKS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 243 VEEFNNILLRVNQDgSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPANME 322
Cdd:PRK09579 237 AEAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLK 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 323 IVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLVLAI 402
Cdd:PRK09579 316 VSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAI 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 403 GLLVDDAIVVVENVERLMsEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFSLTIVSAMVLSV 482
Cdd:PRK09579 396 GLVVDDAIVVVENIHRHI-EEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISG 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 483 LVALILTPALCATLLKPMKHgefgaQRGFFGWFNRFFDTNANRYQNGVRKVIKQGTRYGIIYLAMLAVLAVLFMRMPTSF 562
Cdd:PRK09579 475 IVALTLSPMMCALLLRHEEN-----PSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSEL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 563 LPEEDQGVIMSMVQLPVGATKErtevVLGEMRDYFLENEKE--NVDSVLTVAGFsfagSGQNSGMAFIKLKDWSERkgeE 640
Cdd:PRK09579 550 APEEDQGIIFMMSSSPQPANLD----YLNAYTDEFTPIFKSfpEYYSSFQINGF----NGVQSGIGGFLLKPWNER---E 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 641 RSANAIIGRAMGFLFSIKEAQVFAFNLPPIPELGTATGFDFFLQDRGglGHEKLMQARNQLLGMASQDPNLVRVRPNGME 720
Cdd:PRK09579 619 RTQMELLPLVQAKLEEIPGLQIFGFNLPSLPGTGEGLPFQFVINTAN--DYESLLQVAQRVKQRAQESGKFAFLDIDLAF 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 721 DTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVYLQADAPFRMNPEDLKLWYVRNSAGQMVPFS 800
Cdd:PRK09579 697 DKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLS 776
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 801 AFASTEWSFGSPRLERYNGVSAMEIVGeaAPGKSTGDAMAAIEEMVK-QLPEGIGIEWTGLSFQERQAGSQAPALYAISL 879
Cdd:PRK09579 777 TLITLSDRARPRQLNQFQQLNSAIISG--FPIVSMGEAIETVQQIAReEAPEGFAFDYAGASRQYVQEGSALWVTFGLAL 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 880 LVVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKEL-HDKGMRLG 958
Cdd:PRK09579 855 AIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLrHEQGLSRR 934
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 959 DAVVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLVMR 1028
Cdd:PRK09579 935 EAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAK 1004
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
3-1036 |
6.28e-143 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 454.87 E-value: 6.28e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 3 RFFIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSAQS 82
Cdd:COG3696 7 RFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 83 dSSGNVSVTLTFKPGTDPDIAQVQVQNKLQQAMSLLPQevqqqGVRVQ----KTSSSFLMVAAFISTDGAMTNDDL---A 155
Cdd:COG3696 87 -RFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPA-----GVTPElgpiSTGLGEIYQYTLESDPGKYSLMELrtlQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 156 DYVVANikePLSRLDGVGDITLFG---SQYsmRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAfgklGGTPAVSDQQFTa 232
Cdd:COG3696 161 DWVIRP---QLRSVPGVAEVNSFGgfvKQY--QVLVDPAKLRAYGLTLDDVIEALERNNANVG----GGYIERGGQEYL- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 233 tIMGQTRLSTVEEFNNILLRvNQDGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLA-TGANALDTAEHVRTKLG 311
Cdd:COG3696 231 -VRGIGLIRSLEDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMlKGENALEVIEAVKAKLA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 312 ELSEYFPANMEIVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSIN 391
Cdd:COG3696 309 ELKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISAN 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 392 TLTMFGLVLAIGLLVDDAIVVVENVERLMSE-----EDLSPLEATRKSMTQITGALV-GIALVLsAVFVPMAFFGGSTGA 465
Cdd:COG3696 389 LMSLGGLAIDFGIIVDGAVVMVENILRRLEEnraagTPRERLEVVLEAAREVRRPIFfATLIII-LVFLPIFTLEGVEGK 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 466 IYRQFSLTIVSAMVLSVLVALILTPALCATLLK-PMKHGEfgaqrgffGWFNRFFDtnaNRYQNGVRKVIKQGTRYGIIY 544
Cdd:COG3696 468 LFRPMALTVIFALLGALLLSLTLVPVLASLLLRgKVPEKE--------NPLVRWLK---RLYRPLLRWALRHPKLVLAVA 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 545 LAMLAVLAVLFMRMPTSFLPEEDQGVIMSMVQLPVGATkertevvLGEMRDYF--LENEKENVDSVLTVagFSFAGS--- 619
Cdd:COG3696 537 LVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGIS-------LEESVELGqqVERILKSFPEVESV--VSRTGRaed 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 620 -----GQNSGMAFIKLKDWSE-RKGeeRSANAIIGRamgflfsIKEAqvfafnLPPIPelGTATGFDFFLQDR------- 686
Cdd:COG3696 608 atdpmGVNMSETFVILKPRSEwRSG--RTKEELIAE-------MREA------LEQIP--GVNFNFSQPIQMRvdellsg 670
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 687 --GGLG-------HEKLMQARNQLLGMASQDPNLVRVRPNGMEDTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYV 757
Cdd:COG3696 671 vrADVAvkifgddLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAV 750
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 758 NDFVDRGRVKKVYLQADAPFRMNPEDLKLWYVRNSAGQMVPFSAFASTEWSFGSPRLERYNG-----VSAMeiVGEAAPG 832
Cdd:COG3696 751 GQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGrrrivVQAN--VRGRDLG 828
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 833 KSTGDAMAAIEEMVKqLPEGIGIEWTGlSFQERQAGSQAPALY-AISLLVVFLCLAALYESWSIPFSVMLVVPLGVLGAI 911
Cdd:COG3696 829 SFVAEAQAKVAEQVK-LPPGYYIEWGG-QFENLQRATARLAIVvPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGV 906
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 912 LAATLRGLendvYFQ----VGLLTTIGLSAKNAILIVEFAKELHDKGMRLGDAVVEASRQRLRPILMTSLAFILGVLPLV 987
Cdd:COG3696 907 LALWLRGM----PLSvsagVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMA 982
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*....
gi 498359555 988 ISTGAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLVMRYFTERKHA 1036
Cdd:COG3696 983 LSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRAAA 1031
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
5-1036 |
1.53e-136 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 437.62 E-value: 1.53e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 5 FIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSAQSdS 84
Cdd:PRK10614 7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSS-S 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 85 SGNVSVTLTFKPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQ-GVRVQKTSSSFLMVAAFISTDgaMTNDDLADYVVANIK 163
Cdd:PRK10614 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRpTYRKANPSDAPIMILTLTSDT--YSQGQLYDFASTQLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 164 EPLSRLDGVGDITLFGSQY-SMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAFGklggtpAVSDQQFTATIMGQTRLST 242
Cdd:PRK10614 164 QTISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQG------AVEDGTHRWQIQTNDELKT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 243 VEEFNNILLRVNQdGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPANME 322
Cdd:PRK10614 238 AAEYQPLIIHYNN-GAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAID 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 323 IVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLVLAI 402
Cdd:PRK10614 317 LQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIAT 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 403 GLLVDDAIVVVENVERLMsEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFSLTIVSAMVLSV 482
Cdd:PRK10614 397 GFVVDDAIVVLENISRHL-EAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISL 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 483 LVALILTPALCATLLKPMKHGEFGAQRGffgwFNRFFDTNANRYQNGVRKVIKQGTRYGIIYLAMLAVLAVLFMRMPTSF 562
Cdd:PRK10614 476 LVSLTLTPMMCAWLLKSSKPREQKRLRG----FGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTF 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 563 LPEEDQGVIMSMVQLPVGATkerTEVVLGEMRDYF-LENEKENVDSvltVAGFSfAGSGQNSGMAFIKLKDWSERKgeeR 641
Cdd:PRK10614 552 FPEQDTGRLMGFIQADQSIS---FQAMRGKLQDFMkIIRDDPAVDN---VTGFT-GGSRVNSGMMFITLKPLSERS---E 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 642 SANAIIGRAMGFLFSIKEAQVFafnLPPIPEL-----GTATGFDFFL--QDRGGLGH--EKLMQARNQLlgmasqdPNLV 712
Cdd:PRK10614 622 TAQQVIDRLRVKLAKEPGANLF---LMAVQDIrvggrQSNASYQYTLlsDDLAALREwePKIRKALAAL-------PELA 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 713 RVRPNGMEDTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVYLQADAPFRMNPEDLKLWYVRNS 792
Cdd:PRK10614 692 DVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFVINN 771
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 793 AGQMVPFSAFASteWS-FGSPRLERYNGVSAME-IVGEAAPGKSTGDAMAAIEEMVKQL--PEGI--GIEWTGLSFQERQ 866
Cdd:PRK10614 772 EGKAIPLSYFAK--WQpANAPLSVNHQGLSAAStISFNLPTGKSLSDASAAIERAMTQLgvPSTVrgSFAGTAQVFQETM 849
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 867 AGSQAPALYAISllVVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEF 946
Cdd:PRK10614 850 NSQLILILAAIA--TVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDF 927
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 947 AKELHDKG-MRLGDAVVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFVP---LF 1022
Cdd:PRK10614 928 ALEAQRNGnLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPvvyLF 1007
|
1050
....*....|....
gi 498359555 1023 FVLVMRYFTERKHA 1036
Cdd:PRK10614 1008 FDRLRLRFSRKPKQ 1021
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
2-1040 |
1.22e-130 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 422.22 E-value: 1.22e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 2 ARFFIDRPIFAWVIALVIMLAGAMAIIGLPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSAQ 81
Cdd:PRK10503 13 SRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 82 SdSSGNVSVTLTFKPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQGV--RVQKTSSSFLMVAAfisTDGAMTNDDLADYVV 159
Cdd:PRK10503 93 S-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVysKVNPADPPIMTLAV---TSTAMPMTQVEDMVE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 160 ANIKEPLSRLDGVGDITLFGSQY-SMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAFGKLGGtPAVSdqqftATIMGQT 238
Cdd:PRK10503 169 TRVAQKISQVSGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDG-PTRA-----VTLSAND 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 239 RLSTVEEFNNILLRVnQDGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFP 318
Cdd:PRK10503 243 QMQSAEEYRQLIIAY-QNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 319 ANMEIVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGL 398
Cdd:PRK10503 322 KSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMAL 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 399 VLAIGLLVDDAIVVVENVERLMsEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFSLTIVSAM 478
Cdd:PRK10503 402 TIATGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAI 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 479 VLSVLVALILTPALCATLLkpmKHGEFGAQRGFFGWFNRFFDTNANRYQNGVRKVIKQGTRYGIIYLAMLAVLAVLFMRM 558
Cdd:PRK10503 481 LISAVVSLTLTPMMCARML---SQESLRKQNRFSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 559 PTSFLPEEDQGVIMSMVQLP----VGATKERTEVVLGE-MRDyflenekENVDSVLTVAGFSFAGSGQNSGMAFIKLKDW 633
Cdd:PRK10503 558 PKGFFPVQDNGIIQGTLQAPqsssFANMAQRQRQVADViLQD-------PAVQSLTSFVGVDGTNPSLNSARLQINLKPL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 634 SERkgEERsANAIIGRAMGFLFSIKEAQVFafnLPPIPELG-----TATGFDFFLQ----DRGGLGHEKLMQARNQLlgm 704
Cdd:PRK10503 631 DER--DDR-VQKVIARLQTAVAKVPGVDLY---LQPTQDLTidtqvSRTQYQFTLQatslDALSTWVPKLMEKLQQL--- 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 705 asqdPNLVRVRPNGMEDTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVYLQADAPFRMNPEDL 784
Cdd:PRK10503 702 ----PQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAAL 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 785 KLWYVRNSAGQMVPFSAFASTEWSFGSPRLERYNGVSAMEIVGEAAPGKSTGDAMAAIEEMVKQL--PEGIGIEWTG--L 860
Cdd:PRK10503 778 DTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLnlPADITTQFQGstL 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 861 SFQErqAGSQAPALYAISLLVVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYFQVGLLTTIGLSAKNA 940
Cdd:PRK10503 858 AFQS--ALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNA 935
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 941 ILIVEFA-KELHDKGMRLGDAVVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIGTGVMGGMISATVLAIFFV 1019
Cdd:PRK10503 936 IMMIDFAlAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTT 1015
|
1050 1060
....*....|....*....|....
gi 498359555 1020 PLFFVL---VMRYFTERKHAGEES 1040
Cdd:PRK10503 1016 PVIYLLfdrLALYTKSRFPRHEEE 1039
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
17-1040 |
3.64e-92 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 317.47 E-value: 3.64e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 17 LVIMLAGAMAIIG------LPVAQYPTIAPPAVGISASYPGASAKTVEDSVTQIIEQNMTGLDHLLYMSAQSdSSGNVSV 90
Cdd:TIGR00914 15 LVLLATLVMAILGiwsynrLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLS-RYGLSQV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 91 TLTFKPGTDPDIAQVQVQNKLQQAMSLLPQEVQQQGVRVQKTSSSFLMVA------AFISTDGAMTNDDL---ADYVvan 161
Cdd:TIGR00914 94 TVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTveaeegARKKDGGAYTLTDLrtiQDWI--- 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 162 IKEPLSRLDGVGDI-TLFGSQYSMRVWLDPHKLNRVQMTPADIQAAIKAQNAQVAfgklGGTPAVSDQQFTATIMGQtrL 240
Cdd:TIGR00914 171 IRPQLRTVPGVAEVnSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVG----AGYIERRGEQYLVRAPGQ--V 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 241 STVEEFNNILLRvNQDGSKVQLKDVARVELAGENYDATALYNGQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPAN 320
Cdd:TIGR00914 245 QSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPEG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 321 MEIVYPYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGlvL 400
Cdd:TIGR00914 324 VEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGA--L 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 401 AIGLLVDDAIVVVENVERLMSEED---------LSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGSTGAIYRQFS 471
Cdd:TIGR00914 402 DFGLIVDGAVVIVENAHRRLAEAQhhhgrqltlKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPMA 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 472 LTIVSAMVLSVLVALILTPALCATLL-KPMKHGEfgaqrgffGWFNRFFdtnANRYQNGVRKVIKQGTRYGIIYLAMLAV 550
Cdd:TIGR00914 482 FTVVLALAGAMILSLTFVPAAVALFIrGKVAEKE--------NRLMRVL---KRRYEPLLERVLAWPAVVLGAAAVSIVL 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 551 LAVLFMRMPTSFLPEEDQG-VIMSMVQLPVGATKERTEVvlgemrDYFLENEKENVDSVLTVagFSFAGSGQ-------- 621
Cdd:TIGR00914 551 VVWIASRVGGEFIPSLNEGdLAYQALRIPGTSLAQSVAM------QQTLEKLIKSFPEVARV--FAKTGTAEiatdpmpp 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 622 NSGMAFIKLK---DWSERKG-------EERSANA-IIGRAMGFLFSIKeaqvFAFNlppipELGTATGFDFFLQDRGGLG 690
Cdd:TIGR00914 623 NASDTYIILKpesQWPEGKKtkedlieEIQEATVrIPGNNYEFTQPIQ----MRFN-----ELISGVRSDVAVKVFGDDL 693
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 691 HEKLMQARnQLLGMASQDPNLVRVRPNGMEDTPQLDIKIDYEKALAQGLSITDINNTLSAAWGSSYVNDFVDRGRVKKVY 770
Cdd:TIGR00914 694 DDLDATAE-KISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIV 772
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 771 LQADAPFRMNPEDLK-----LWYVRNSAGQMVPFSAFASTEWSFGSPRLERYNGVSAMEI---VGEAAPGKSTGDAMAAI 842
Cdd:TIGR00914 773 IRLPESLRESPQALRqlpipLPLSEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVsanVRGRDLGSFVDDAKKAI 852
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 843 EEMVKqLPEGIGIEWTGlSFQERQAGSQAPALYA-ISLLVVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLEN 921
Cdd:TIGR00914 853 AEQVK-LPPGYWITWGG-QFEQLQSATKRLQIVVpVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPL 930
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 922 DVYFQVGLLTTIGLSAKNAILIVEFAKELHDKGMRLGDAVVEASRQRLRPILMTSLAFILGVLPLVISTGAGASSRNAIG 1001
Cdd:TIGR00914 931 SISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLA 1010
|
1050 1060 1070
....*....|....*....|....*....|....*....
gi 498359555 1002 TGVMGGMISATVLAIFFVPLFFVLVMRyfteRKHAGEES 1040
Cdd:TIGR00914 1011 TVVIGGIITATLLTLFVLPALYRLVHR----RRHKGRKE 1045
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
286-1034 |
1.37e-20 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 98.01 E-value: 1.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 286 TAAVAIKLATG--ANALDTAEHVRTKLGELSEYFPANMEIVY---PYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQ 360
Cdd:COG1033 161 ATLIVVTLDPDplSSDLDRKEVVAEIRAIIAKYEDPGVEVYLtgfPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 361 NFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTM--FGLVLAIGllVDDAIVVVENVERLMsEEDLSPLEATRKSMTQI 438
Cdd:COG1033 241 SLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTIlvPPLLLAIG--IDYGIHLLNRYREER-RKGLDKREALREALRKL 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 439 TGALVGIALVLSAVFVPMAFfggSTGAIYRQFSLTIVSAMVLSVLVALILTPALCATLLKPMKHGEFGAQRGFFGWFNRF 518
Cdd:COG1033 318 GPPVLLTSLTTAIGFLSLLF---SDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLLAK 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 519 FdtnanryqngVRKVIKqgtRYGIIYLAMLAVLAVLFmrmptsflpeedqgvimsmvqlpVGATKERTEvvlGEMRDYFL 598
Cdd:COG1033 395 L----------ARFVLR---RPKVILVVALVLAVVSL-----------------------YGISRLKVE---YDFEDYLP 435
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 599 ENEKENVDsvltvagfsfagsgqnsgMAFIklkdwserkgeersaNAIIGRAMGFLFSIKeaqvfafnlppipelgtatg 678
Cdd:COG1033 436 EDSPIRQD------------------LDFI---------------EENFGGSDPLEVVVD-------------------- 462
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 679 fdffLQDRGGLGHEKLMQARNQLLGMASQDPNLVRVrpngmedtpqldikidyekalaqgLSITDINNTLSAAWGSSYVN 758
Cdd:COG1033 463 ----TGEPDGLKDPEVLKEIDRLQDYLESLPEVGKV------------------------LSLADLVKELNQALNEGDPK 514
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 759 DFV---DRGRVKKVYLQADAPFRMNPEDLklwyvRNSAGQMVPFSAfastewsfgsprleRYNGVSAMEIVgeaapgkst 835
Cdd:COG1033 515 YYAlpeSRELLAQLLLLLSSPPGDDLSRF-----VDEDYSAARVTV--------------RLKDLDSEEIK--------- 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 836 gDAMAAIEEMVKQL--PEGIGIEWTGLSF-----QERQAGSQAPALyAISLLVVFLCLAALYESWSIPFSVML--VVPLG 906
Cdd:COG1033 567 -ALVEEVRAFLAENfpPDGVEVTLTGSAVlfaaiNESVIESQIRSL-LLALLLIFLLLLLAFRSLRLGLISLIpnLLPIL 644
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 907 VLGAILAATlrglenDVYFQVGLLT----TIGLSAKNAILIVEFAKELHDKGMRLGDAVVEASRQRLRPILMTSLAFILG 982
Cdd:COG1033 645 LTFGLMGLL------GIPLNIATAVvasiALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAG 718
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*..
gi 498359555 983 VLPLVIStgagassrNAIGTGVMG-----GMISATVLAIFFVPLFFVLVMRYFTERK 1034
Cdd:COG1033 719 FGVLLFS--------SFPPLADFGlllalGLLVALLAALLLLPALLLLLDPRIAKKR 767
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
285-562 |
6.50e-06 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 50.15 E-value: 6.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 285 ATAAVAIKLATGANALDTAEHVRTKLGELSeyfPANMEIVY---PYDTTPFVKISIEEVVQTLIEAIFLVFCVMYLFLQN 361
Cdd:COG2409 116 ALVTVTLDGDAGDEAAEAVDALRDAVAAAP---APGLTVYVtgpAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRS 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 362 FRATLIPTIAVPVVLLGTFGVMAAFG-------FSINTLTMFGLVLAI--GLLVddaivvvenV----ERLMSEEDlsPL 428
Cdd:COG2409 193 LVAALLPLLTAGLAVGVALGLLALLAaftdvssFAPNLLTMLGLGVGIdyALFL---------VsryrEELRAGED--RE 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 429 EATRKSMTQ------ITGALVGIALvLSAVFVPMAFFggstgaiyRQFSLTIVSAMVLSVLVALILTPALCATL----LK 498
Cdd:COG2409 262 EAVARAVATagravlFSGLTVAIAL-LGLLLAGLPFL--------RSMGPAAAIGVAVAVLAALTLLPALLALLgrrvFW 332
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 498359555 499 PMKHGEFGAQRGFFGWFNRFfdtnanryqngVRKVIKQGTRYGIIYLAMLAVLAVLFMRMPTSF 562
Cdd:COG2409 333 PRRPRRRRAAAPESGFWRRL-----------ARAVVRRPVPVLVAAVAVLLALALPALGLRLGL 385
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
833-1040 |
7.93e-06 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 49.86 E-value: 7.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 833 KSTGDAMAAIEEMVKQL-PEGIGIEWTGLSFQE----RQAGSQAPALYAISLLVVFLCLAALYESWSIPFSVMLVVPLGV 907
Cdd:COG1033 177 LDRKEVVAEIRAIIAKYeDPGVEVYLTGFPVLRgdiaEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAV 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 908 LGAILAATLRGLENDVYFQV--GLLTTIGLSakNAI-LIVEFAKELHdKGMRLGDAVVEASRQRLRPILMTSLAFILGVL 984
Cdd:COG1033 257 IWTLGLMGLLGIPLSPLTILvpPLLLAIGID--YGIhLLNRYREERR-KGLDKREALREALRKLGPPVLLTSLTTAIGFL 333
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 498359555 985 PLVISTGAGASSrnaIGTGVMGGMISATVLAIFFVPLFFVLVMRYFTERKHAGEES 1040
Cdd:COG1033 334 SLLFSDIPPIRD---FGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPP 386
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
347-525 |
9.83e-06 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 48.83 E-value: 9.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 347 AIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAF----GFSINTLT-MFGLVLAIGLLVDDAIVVVENV-ERLM 420
Cdd:pfam03176 151 TLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAQGLVAILahilGIGLSTFAlNLLVVLLIAVGTDYALFLVSRYrEELR 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 421 SEEDlsPLEATRKSMTQITGALVGIALVLSAVFVPMAFfggSTGAIYRQFSLTIVSAMVLSVLVALILTPALCATLlkpm 500
Cdd:pfam03176 231 AGED--REEAVIRAVRGTGKVVTAAGLTVAIAMLALSF---ARLPVFAQVGPTIAIGVLVDVLAALTLLPALLALL---- 301
|
170 180
....*....|....*....|....*
gi 498359555 501 khgefgaqrGFFGWFNRFFDTNANR 525
Cdd:pfam03176 302 ---------GRWGLWPPKRDRTARW 317
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
341-492 |
1.66e-05 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 48.89 E-value: 1.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 341 VQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLVLAIGLLVDDAIVVVENVERlm 420
Cdd:pfam02460 642 IQNIVITLICMFIVCFLFIPNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPISMITIIMSIGFSVDFSAHIAYHFVR-- 719
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 498359555 421 SEEDlSPLEATRKSMTQI-----TGALVGIALVLSAVFVPmaffggsTGAIyRQFSLTIVSAMVLSVLVALILTPAL 492
Cdd:pfam02460 720 SRGD-TPAERVVDALEALgwpvfQGGLSTILGVLVLLFVP-------SYMV-VVFFKTVFLVVAIGLLHGLFILPII 787
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
341-492 |
2.20e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 48.68 E-value: 2.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 341 VQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLVLAIGLLVDdaiVVVENVERLM 420
Cdd:TIGR00921 196 GTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGID---YGIQTLNRYE 272
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 498359555 421 SEEDL--SPLEATRKSMTQITGALVGIALVLSAVFVPMAFfggSTGAIYRQFSLTIVSAMVLSVLVALILTPAL 492
Cdd:TIGR00921 273 EERDIgrAKGEAIVTAVRRTGRAVLIALLTTSAGFAALAL---SEFPMVSEFGLGLVAGLITAYLLTLLVLPAL 343
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
347-491 |
2.64e-05 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 48.31 E-value: 2.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 347 AIFLVFCVMYLFLQNFRATLIpTIAVPVV-LLGTFGVMAAFGFSINTLTMFGLVLAIGLLVDDAIvvvenverLMSEEDL 425
Cdd:COG4258 648 ALLLILLLLLLRLRSLRRALR-VLLPPLLaVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL--------FFTEGLL 718
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 498359555 426 SPLEATRksmtqitgALVGIAL-VLSAV--FVPMAFfgGSTGAIyRQFSLTIVSAMVLSVLVALILTPA 491
Cdd:COG4258 719 DKGELAR--------TLLSILLaALTTLlgFGLLAF--SSTPAL-RSFGLTVLLGILLALLLAPLLAPR 776
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
338-492 |
2.73e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 48.29 E-value: 2.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 338 EEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFG--FSINTLTMFGLVLAIGllVDDAIVVven 415
Cdd:TIGR00921 567 EGMRRMTIAGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGipSFLAMATTISIILGLG--MDYSIHL--- 641
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 498359555 416 VERLMSEED-LSPLEATRKSMTQITGALVGIALVLSAVFVPMAFfggSTGAIYRQFSLTIVSAMVLSVLVALILTPAL 492
Cdd:TIGR00921 642 AERYFEERKeHGPKEAITHTMERTGPGILFSGLTTAGGFLSLLL---SHFPIMRNFGLVQGIGVLSSLTAALVVFPAL 716
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
850-1020 |
2.84e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 48.29 E-value: 2.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 850 PEGIGIEWTG---LSFQ-ERQAGSQAPALYAISLLVVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDVYF 925
Cdd:TIGR00921 170 PSGKFLDVTGspaINYDiEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATT 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 926 QVGLLTTIGLSAKNAILIVEFAKELHDKGMRLGDAVVEASRQRLRPILMTSLAFILGVLPLVIStgaGASSRNAIGTGVM 1005
Cdd:TIGR00921 250 LLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALS---EFPMVSEFGLGLV 326
|
170
....*....|....*
gi 498359555 1006 GGMISATVLAIFFVP 1020
Cdd:TIGR00921 327 AGLITAYLLTLLVLP 341
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
336-486 |
2.96e-05 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 46.10 E-value: 2.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 336 SIEEVVQTLIEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLgTFGVMAAFGFSINTLTMFGLVLAIGLLVDDAIVVVEN 415
Cdd:TIGR00916 45 LIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVIL-ILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFDR 123
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 498359555 416 V-ERLMSEEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGstGAIyRQFSLTIVSAMVLSVLVAL 486
Cdd:TIGR00916 124 IrEELRKYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGG--GAI-KGFALTLGIGVIAGTYSSI 192
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
318-492 |
9.15e-05 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 46.26 E-value: 9.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 318 PANMEIVYPYDTTP-FVKISIEEVVQTLIEAIFLVFCVMYLFLQNFRatLIPTIAVPVVLLGTFGVMAAFGFsinTLTM- 395
Cdd:COG0342 250 PAPLEIVEERTVGPtLGADSIEKGLIAGLIGLLLVALFMLLYYRLPG--LVANIALALNVVLLLGVLSLLGA---TLTLp 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 396 --FGLVLAIGLLVDDaivvveNV---ERLMSEedlspLEATRKSMTQItgaLVGIALVLSAVF----------VPMAFFG 460
Cdd:COG0342 325 giAGIILTIGMAVDA------NVlifERIREE-----LRAGRSLRAAI---EAGFKRAFSTILdanvttliaaVVLFVLG 390
|
170 180 190
....*....|....*....|....*....|..
gi 498359555 461 gsTGAIyRQFSLTIVSAMVLSVLVALILTPAL 492
Cdd:COG0342 391 --TGPV-KGFAVTLILGILISMFTAVPVTRPL 419
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
317-492 |
1.49e-04 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 45.36 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 317 FPANMEIVYPYDTTP-FVKISIEEVVQTLIEAIFLVFCVMYLFLQNFraTLIPTIAVPVVLLGTFGVMAAFGFSINTLTM 395
Cdd:TIGR01129 226 LPAPLQILEERTIGPsLGADSIEAGIKAGLIGLVLVLVFMILYYRLF--GLIAAIALVINIVLILAILSAFGATLTLPGI 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 396 FGLVLAIGLLVDDAIVVVENVerlmsEEDL----SPLEAT----RKSMTQITGAlvGIALVLSAVFvpMAFFGgsTGAIy 467
Cdd:TIGR01129 304 AGLILTIGMAVDANVLIYERI-----KEELrlgkSVRQAIeagfERAFSTIFDA--NITTLIAALI--LYVFG--TGPV- 371
|
170 180
....*....|....*....|....*
gi 498359555 468 RQFSLTIVSAMVLSVLVALILTPAL 492
Cdd:TIGR01129 372 KGFAVTLAIGIIASLFTALVFTRLL 396
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
336-498 |
5.67e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 44.07 E-value: 5.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 336 SIEEVVQTLIEAIFLVFCVMYLFLQnfRATLIPTIAVPVVLLGTFGVMAAFGFsinTLTM---FGLVLAIGLLVDDAIVV 412
Cdd:PRK13024 264 AIDAGIIAGIIGFALIFLFMLVYYG--LPGLIANIALLLYIFLTLGALSSLGA---VLTLpgiAGLVLGIGMAVDANVLI 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 413 VENVerlmsEEDL----SPLEATRKSM---------TQITGALVGIALvlsavFvpmaFFGgsTGAIyRQFSLTIVSAMV 479
Cdd:PRK13024 339 FERI-----KEELrkgkSLKKAFKKGFknafstildSNITTLIAAAIL-----F----FFG--TGPV-KGFATTLIIGIL 401
|
170
....*....|....*....
gi 498359555 480 LSVLVALILTPALCATLLK 498
Cdd:PRK13024 402 ASLFTAVFLTRLLLELLVK 420
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
347-498 |
6.15e-04 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 42.21 E-value: 6.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 347 AIFLVFCVMYLFL--QNFRATLIPTIAVPVVLLgTFGVMAAFGFSINTLTMFGLVLAIGLLVDDAIVVVENV-ERLMSEE 423
Cdd:pfam02355 38 LFALLLILIYVGLrfEWRFALGAIIALAHDVII-TVGVFSLFGIEVDLATVAALLTIIGYSVNDTVVVFDRVrENLRKKT 116
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 498359555 424 DLSPLEATRKSMTQITGALVGIALVLSAVFVPMAFFGGStgaIYRQFSLTIVSAMVLSVLVALILTPALCATLLK 498
Cdd:pfam02355 117 RATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGG---SLKDFSLALLVGVIVGTYSSIFIASPILLDLGE 188
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
8-497 |
3.55e-03 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 41.49 E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 8 RPIFAWVIALVIMLAGAMAIIGLPV-----AQYPTIAPPAVGISAS---YPGASAktveDSVTQIIE-----QNMTGLDH 74
Cdd:TIGR00833 360 RPWPILVTTLIISGVSLLALPLIRTgyddeKMIPTDLESVQGYEAAdrhFPGNSM----DPMVVMIKsdhdvRNPALLAD 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 75 LLYMSAQSDSSGNVSVT--LTFKPGTDPDIAQVQVQ-----NKLQQAMSLLPQEVQ---QQGVRVQKTSSSFLMVAAFIS 144
Cdd:TIGR00833 436 IDRFEREIKAVPGINMVqeTQRPDGVVIKKTYLTFQagnlgDQLDEFSDQLTSRQAyllQDAEKIAEAIAGLRLVQAGMR 515
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 145 TDGAMTNDDLADyVVANIKEPLSRLDGVGDITLFGSQYSMRVWLDPHKLN-------RVQMTPADIQAAIKAQNAQvAFG 217
Cdd:TIGR00833 516 LDGENLGQVSLA-VRLMQQAISKLQGSAGDVFDIFDPLRRFVAAIPECRAnpvcsvaREIVQAADTVVSSAAKLAD-AAG 593
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 218 KLGGTPAVSDQQFTATImgqTRLSTVEEFNNILLRVNQDGSKVQ-----LKDVARVELAGENYDATALYNGQATAAVAIK 292
Cdd:TIGR00833 594 QLARGIADVASALSQVS---GLPNALDGIGTQLAQMRESAAGVQdllneLSDYSMTMGKLKGNAMGVDFYAPPRIFTDPN 670
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 293 LATGANALDTAEHVRTKLGELSEYFPANMEIVYPY-----------DTTPFVKISIE-----------------EVVQTL 344
Cdd:TIGR00833 671 FKAVLDYFLSPDGHAARLLVYGDGSPAGDQGAQEFnairtvaeeaiQRADLEPAKVElagvsavnrdlrdlvnsDLGLIS 750
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 345 IEAIFLVFCVMYLFLQNFRATLIPTIAVPVVLLGTFGVMAAFGFSINTLTMFGLVLAIGLLVDDAIVVVEN---VERLMS 421
Cdd:TIGR00833 751 IITLAIVFMILALLLRAPVAPIVLIGSVALSYLWALGLSVLAFQHILGAELHWSVLAGVFVLLVALGVDYNmllVSRIKE 830
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 498359555 422 EEDLSPLEATRKSMTQITGALVGIALVLSAVFVPMAffgGSTGAIYRQFSLTIVSAMVLSVLVALILTPALCATLL 497
Cdd:TIGR00833 831 ESPAGNRTGIIRALGSTGGVITAAGLVFAGTMAALA---SAQLTAIAQFGFTVGVGILLDTFIVRSVTVPALTLLL 903
|
|
| 2A060601 |
TIGR00917 |
Niemann-Pick C type protein family; The model describes Niemann-Pick C type protein in ... |
298-475 |
5.45e-03 |
|
Niemann-Pick C type protein family; The model describes Niemann-Pick C type protein in eukaryotes. The defective protein has been associated with Niemann-Pick disease which is described in humans as autosomal recessive lipidosis. It is characterized by the lysosomal accumulation of unestrified cholesterol. It is an integral membrane protein, which indicates that this protein is most likely involved in cholesterol transport or acts as some component of cholesterol homeostasis. [Transport and binding proteins, Other]
Pssm-ID: 273337 [Multi-domain] Cd Length: 1205 Bit Score: 41.05 E-value: 5.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 298 NALDTAEHVRTKLGELSEY--FPANMEIVYPYDTTPFVKISIEEVVQTLiEAIFLVfcVMYLFLQNFRATLIPTIAVPVV 375
Cdd:TIGR00917 1011 NAMRAAQEFAAKVSRSSKMevYPYSVFYVFFEQYLTIWKTAIINLSIAL-GAIFIV--CLFLLQLNALSVVNLIMSVGMA 1087
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 376 LLGTFGVMAAFGFSINTLTMFGLVLAIGLLVD------DAIVVVENVERLM-SEEDLSPLEATRKSMTQIT--GALVGIA 446
Cdd:TIGR00917 1088 VVFCVGIMHLWSISLNAVSVVNSVMHKGIAIEfcthinAQFSTGKHFSRNHrAKEALGGMGSSVFSGITLTklVGVVVLG 1167
|
170 180 190
....*....|....*....|....*....|....*..
gi 498359555 447 LVLSAVFV--------PMAFFGGSTGAIYRQFSLTIV 475
Cdd:TIGR00917 1168 FSRSEIFVvyyfrmylALVLLGFLHGLVFLPVLLSVL 1204
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
283-485 |
8.46e-03 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 39.18 E-value: 8.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 283 GQATAAVAIKLATGANALDTAEHVRTKLGELSEYFPA-NMEIVYPydttpfvKISiEEVVQTLIEAIfLVFCVMYLFLQN 361
Cdd:TIGR00966 46 SSHTIMIRIPTLDTEQSEELREALEEALKNVDPDAEIrSIDAVGP-------SVG-GELARKAVLAL-LAALVLILIYIT 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 362 FRATLIPTIAVPVVLLG----TFGVMAAFGFSINTLTMFGLVLAIGLLVDDAIVVVENV-ERLMSEEDLSPLEATRKSMT 436
Cdd:TIGR00966 117 VRFEWRFALGAIVALVHdviiTVGVYSLFGIEVNLTTVAALLTIIGYSINDTVVVFDRIrENLRKYTRKTFTEVINLSIN 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 498359555 437 QITGALVGIALVLSAVFVPMAFFGGstGAIyRQFSLTIVSAMVL----SVLVA 485
Cdd:TIGR00966 197 QTLSRTINTSLTTLLAVLALYVFGG--GVI-KDFSLALLVGVIVgtysSIFIA 246
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
807-1026 |
8.86e-03 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 40.13 E-value: 8.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 807 WSFGSPRLERYNGVSAMEIVG-EAAPGKSTGDAMAAIEEMVKQL-PEGIGIEWTGLSFQERQAGSQAPA----LYAISLL 880
Cdd:COG2409 101 WDDPAAGLVSEDGKAALVTVTlDGDAGDEAAEAVDALRDAVAAApAPGLTVYVTGPAALAADLNEAFEEdlgrAELITLP 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498359555 881 VVFLCLAALYESWSIPFSVMLVVPLGVLGAILAATLRGLENDV-YFQVGLLTTIGLSAknAI-----LIVEFAKELHdKG 954
Cdd:COG2409 181 VALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAAFTDVsSFAPNLLTMLGLGV--GIdyalfLVSRYREELR-AG 257
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 498359555 955 MRLGDAVVEASRQRLRPILMTSLAFILGVLPLVIstgAGASSRNAIGTGVMGGMISATVLAIFFVPLFFVLV 1026
Cdd:COG2409 258 EDREEAVARAVATAGRAVLFSGLTVAIALLGLLL---AGLPFLRSMGPAAAIGVAVAVLAALTLLPALLALL 326
|
|
| |
