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Conserved domains on  [gi|498360490|ref|WP_010674646|]
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MULTISPECIES: cell division topological specificity factor MinE [Aeromonas]

Protein Classification

cell division topological specificity factor MinE( domain architecture ID 10011362)

cell division topological specificity factor MinE prevents cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites, ensuring cell division at the proper site

CATH:  3.30.1070.10
Gene Symbol:  minE
Gene Ontology:  GO:0051301
PubMed:  9393861|11062554
SCOP:  4001444

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
minE PRK00296
cell division topological specificity factor MinE; Reviewed
 1-88 2.20e-43

cell division topological specificity factor MinE; Reviewed


:

Pssm-ID: 234718  Cd Length: 86  Bit Score: 135.36  E-value: 2.20e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498360490  1 MSLLDYFRSnKKQNTAQLAKERLQIIVAHERSSRGGPDYLPQLKQDILDVIRKYVQIDPDKITVQLDqKSDELSVLELNI 80
Cdd:PRK00296  1 MSLLDFFRS-RKKSTANVAKERLQIIVAHERSSRGEPDYLPQLRKEILEVIAKYVQIDPDKVSVQLD-KDGDISTLELNV 78


                ....*...
gi 498360490 81 TFADDQKK 88
Cdd:PRK00296 79 TLPEAEEK 86
 
Name Accession Description Interval E-value
minE PRK00296
cell division topological specificity factor MinE; Reviewed
 1-88 2.20e-43

cell division topological specificity factor MinE; Reviewed


Pssm-ID: 234718  Cd Length: 86  Bit Score: 135.36  E-value: 2.20e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498360490  1 MSLLDYFRSnKKQNTAQLAKERLQIIVAHERSSRGGPDYLPQLKQDILDVIRKYVQIDPDKITVQLDqKSDELSVLELNI 80
Cdd:PRK00296  1 MSLLDFFRS-RKKSTANVAKERLQIIVAHERSSRGEPDYLPQLRKEILEVIAKYVQIDPDKVSVQLD-KDGDISTLELNV 78


                ....*...
gi 498360490 81 TFADDQKK 88
Cdd:PRK00296 79 TLPEAEEK 86
MinE COG0851
Septum formation topological specificity factor MinE [Cell cycle control, cell division, ...
 1-87 4.38e-37

Septum formation topological specificity factor MinE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440612  Cd Length: 84  Bit Score: 119.44  E-value: 4.38e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498360490  1 MSLLDYFRSNKKqNTAQLAKERLQIIVAHERSSRGgPDYLPQLKQDILDVIRKYVQIDPDKITVQLDQKsDELSVLELNI 80
Cdd:COG0851   1 MSLLDFFRGRKK-SSADVAKERLQLVLAHDRAGLS-PDYLEQLKKEILEVISKYVEIDEDAVEVSLERE-DDLSALEANI 77


                ....*..
gi 498360490 81 TFADDQK 87
Cdd:COG0851  78 PLPRVKR 84
MinE pfam03776
Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to ...
 15-82 1.09e-28

Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to code for three gene products (MinC, MinD, and MinE) whose coordinate action is required for proper placement of the division septum. The minE gene codes for a topological specificity factor that, in wild-type cells, prevents the division inhibitor from acting at internal division sites while permitting it to block septation at polar sites.


Pssm-ID: 461046  Cd Length: 67  Bit Score: 97.45  E-value: 1.09e-28
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 498360490  15 TAQLAKERLQIIVAHERSsRGGPDYLPQLKQDILDVIRKYVQIDPDKITVQLDQKSDELSVLELNITF 82
Cdd:pfam03776  1 SANVAKERLQLILAHDRA-DLSPDYLEQLKNEILEVISKYVEIDEEKVEVQLEQDDGDVSVLEANIPL 67
minE TIGR01215
cell division topological specificity factor MinE; This protein is involved in the process of ...
 1-84 2.20e-27

cell division topological specificity factor MinE; This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division]


Pssm-ID: 188120  Cd Length: 81  Bit Score: 94.73  E-value: 2.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498360490   1 MSLLDYFRSnKKQNTAQLAKERLQIIVAHERSSRGgPDYLPQLKQDILDVIRKYVQIDPDKITVQLDqKSDELSVLELNI 80
Cdd:TIGR01215  1 MSLLEFFKS-RKKNSAEVAKDRLKLILAHERAQLA-PEYLEELRKEILEVISKYVEIDPEMVEVSLE-SQGDMSVLELNI 77


                 ....
gi 498360490  81 TFAD 84
Cdd:TIGR01215 78 TLPE 81
 
Name Accession Description Interval E-value
minE PRK00296
cell division topological specificity factor MinE; Reviewed
 1-88 2.20e-43

cell division topological specificity factor MinE; Reviewed


Pssm-ID: 234718  Cd Length: 86  Bit Score: 135.36  E-value: 2.20e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498360490  1 MSLLDYFRSnKKQNTAQLAKERLQIIVAHERSSRGGPDYLPQLKQDILDVIRKYVQIDPDKITVQLDqKSDELSVLELNI 80
Cdd:PRK00296  1 MSLLDFFRS-RKKSTANVAKERLQIIVAHERSSRGEPDYLPQLRKEILEVIAKYVQIDPDKVSVQLD-KDGDISTLELNV 78


                ....*...
gi 498360490 81 TFADDQKK 88
Cdd:PRK00296 79 TLPEAEEK 86
MinE COG0851
Septum formation topological specificity factor MinE [Cell cycle control, cell division, ...
 1-87 4.38e-37

Septum formation topological specificity factor MinE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440612  Cd Length: 84  Bit Score: 119.44  E-value: 4.38e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498360490  1 MSLLDYFRSNKKqNTAQLAKERLQIIVAHERSSRGgPDYLPQLKQDILDVIRKYVQIDPDKITVQLDQKsDELSVLELNI 80
Cdd:COG0851   1 MSLLDFFRGRKK-SSADVAKERLQLVLAHDRAGLS-PDYLEQLKKEILEVISKYVEIDEDAVEVSLERE-DDLSALEANI 77


                ....*..
gi 498360490 81 TFADDQK 87
Cdd:COG0851  78 PLPRVKR 84
MinE pfam03776
Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to ...
 15-82 1.09e-28

Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to code for three gene products (MinC, MinD, and MinE) whose coordinate action is required for proper placement of the division septum. The minE gene codes for a topological specificity factor that, in wild-type cells, prevents the division inhibitor from acting at internal division sites while permitting it to block septation at polar sites.


Pssm-ID: 461046  Cd Length: 67  Bit Score: 97.45  E-value: 1.09e-28
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 498360490  15 TAQLAKERLQIIVAHERSsRGGPDYLPQLKQDILDVIRKYVQIDPDKITVQLDQKSDELSVLELNITF 82
Cdd:pfam03776  1 SANVAKERLQLILAHDRA-DLSPDYLEQLKNEILEVISKYVEIDEEKVEVQLEQDDGDVSVLEANIPL 67
minE TIGR01215
cell division topological specificity factor MinE; This protein is involved in the process of ...
 1-84 2.20e-27

cell division topological specificity factor MinE; This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division]


Pssm-ID: 188120  Cd Length: 81  Bit Score: 94.73  E-value: 2.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498360490   1 MSLLDYFRSnKKQNTAQLAKERLQIIVAHERSSRGgPDYLPQLKQDILDVIRKYVQIDPDKITVQLDqKSDELSVLELNI 80
Cdd:TIGR01215  1 MSLLEFFKS-RKKNSAEVAKDRLKLILAHERAQLA-PEYLEELRKEILEVISKYVEIDPEMVEVSLE-SQGDMSVLELNI 77


                 ....
gi 498360490  81 TFAD 84
Cdd:TIGR01215 78 TLPE 81
PRK13989 PRK13989
cell division topological specificity factor MinE; Provisional
 1-85 1.09e-24

cell division topological specificity factor MinE; Provisional


Pssm-ID: 184442  Cd Length: 84  Bit Score: 88.22  E-value: 1.09e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498360490  1 MSLLDyFRSNKKQNTAQLAKERLQIIVAHERSSRG-GPDYLPQLKQDILDVIRKYVQIDPDKITVQLDqKSDELSVLELN 79
Cdd:PRK13989  1 MSILS-FLLGEKKKTASVAKERLQIIIAHERVGGRqPPDYLPALQKELVAVISKYVKISPDDIRVSLE-RQDNLEVLEVK 78


                ....*.
gi 498360490 80 ITFADD 85
Cdd:PRK13989 79 IELPQA 84
PRK13987 PRK13987
cell division topological specificity factor MinE; Provisional
 4-72 1.11e-11

cell division topological specificity factor MinE; Provisional


Pssm-ID: 237579  Cd Length: 91  Bit Score: 55.44  E-value: 1.11e-11
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498360490  4 LDYFRS-NKKQNTAQLAKERLQIIVAHERSSRGgPDYLPQLKQDILDVIRKYVQIDPDKITVQLDQKSDE 72
Cdd:PRK13987  1 MDLFKFfSKKPTSKDVAKERLKLILIHDRGDIS-PDVLEMIKEDILKVISKYVEIDNEDVDIKMTKSEEI 69
PRK13988 PRK13988
cell division topological specificity factor MinE; Provisional
 1-67 6.15e-11

cell division topological specificity factor MinE; Provisional


Pssm-ID: 184441  Cd Length: 97  Bit Score: 53.61  E-value: 6.15e-11
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 498360490  1 MSLLDY----FRSNKKqnTAQLAKERLQIIVAHERSSRGgPDYLPQLKQDILDVIRKYVQIDPDKITVQLD 67
Cdd:PRK13988  1 MTLRDLleklFGRQPA--SASTARERLQLVLAHDRADLS-PELLEQMRKEILEVVARYVEIDPEEGEVSLE 68
PRK13990 PRK13990
cell division topological specificity factor MinE; Provisional
 3-82 1.24e-09

cell division topological specificity factor MinE; Provisional


Pssm-ID: 172492  Cd Length: 90  Bit Score: 50.12  E-value: 1.24e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498360490  3 LLDYFRSNKKQNTAQLAKERLQIIVAHE------RSSRGGPDYLPQLKQDILDVIRKYVQIDPDKITvQLDQK---SDEL 73
Cdd:PRK13990  2 LAKLFGLSKKQQSASVAKERLQIIVAHQrselhpRSSKISSHLLAELKDEIIEVVKKYVALSEENIR-DIDLKvedSSKN 80


                ....*....
gi 498360490 74 SVLELNITF 82
Cdd:PRK13990 81 STIEVNIPF 89
PRK13991 PRK13991
cell division topological specificity factor MinE; Provisional
 1-66 7.25e-09

cell division topological specificity factor MinE; Provisional


Pssm-ID: 172493  Cd Length: 87  Bit Score: 47.95  E-value: 7.25e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 498360490  1 MSLLDYFRSNKKQNTAQLAKERLQIIVAHERsSRGGPDYLPQLKQDILDVIRKYVQ-IDPDKITVQL 66
Cdd:PRK13991  1 MSFLDGLFGRKRDSSSELAKQRLLTVLVHDR-VKLTPEMMEQMKADLAEVIKRYVPaIDAEAIEVTL 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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