NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|498379453|ref|WP_010693609|]
View 

AAA family ATPase [Treponema denticola]

Protein Classification

ATP-binding protein( domain architecture ID 10561305)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain and a C-terminal PD-(D/E)XK nuclease domain, which found in restriction endonuclease-like proteins that are involved in numerous nucleic acid cleavage events important for various cellular processes

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
AAA-ATPase_like pfam09820
Predicted AAA-ATPase; This family contains many hypothetical bacterial proteins. This family ...
 10-296 3.41e-133

Predicted AAA-ATPase; This family contains many hypothetical bacterial proteins. This family was previously the N-terminal part of the Pfam DUF1703 (pfam08011) family before it was split into two. This region is predicted to be an AAA-ATPase domain.


:

Pssm-ID: 430851  Cd Length: 278  Bit Score: 388.04  E-value: 3.41e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453   10 PIGVQSFEKMRNDKYLYVDKTKYVYNLVCTSSPYFLSRPRRFGKSLFLSTLKAYFLGQKELFKGLYIEKAEekraeiekT 89
Cdd:pfam09820   1 PIGIQSFEEIREEGYYYVDKTAFIYQLVKQGKYYFLSRPRRFGKSLLLSTLEAYFDGKKELFGGLYIGKLP--------T 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453   90 DAWVEYPVLYMDFNIGRYDEPNSLKSHLNIVLSQFEEIYG-ANKQEEEPAQRFAGIVQRAYEKTGKQVVILVDEYDKPLL 168
Cdd:pfam09820  73 DWWNKYPVLRIDFSAGKYDSPDELEERLNRYLSNWEKLFGeTYEDEGSPGGRLAELIRRAYEKTGQQVVVLIDEYDKPIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453  169 QTMGvNEALNEEFRNTLKAFYSVTKTCDQYIRFAFLTGVTKFSKVSIFSDLNNLQDISMLNDYAEICGLTQTEIEKTFKP 248
Cdd:pfam09820 153 DNLS-DEELYREMRDFLRSFYGVLKGLDGYLRFVFLTGVSKFTKDSIFSGLNNLNDITLDPRYSAICGFTEEELETIFDE 231

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 498379453  249 EIERLAtnTKNSYDKMLEELKKRYDGYKFSV-LGESVYNPFSILNTLNS 296
Cdd:pfam09820 232 YLEELA--LPQTYDEMIEELKEWYNGYSFGEdSGESVYNPFSILNFFDK 278
PDDEXK_9 pfam08011
PD-(D/E)XK nuclease superfamily; This family contains many hypothetical bacterial proteins. It ...
 440-534 1.62e-24

PD-(D/E)XK nuclease superfamily; This family contains many hypothetical bacterial proteins. It has been identified as a member of the PD-(D/E)XK nuclease superfamily through transitive meta profile searches. DUF1703 has the predicted secondary structure pattern of the restriction endonuclease-like fold core and contains an additional beta-strand at the C-terminus.


:

Pssm-ID: 400391  Cd Length: 104  Bit Score: 97.71  E-value: 1.62e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453  440 LREQNYQTAVYLIFKL-MGQFVETEIHCAKGRADCIVH---TKDSIYIFEFK-----LMSAGSADDAIAQIKEKGYASQF 510
Cdd:pfam08011   1 EFEGYYASVFYAYFALsLGYEVIPEDETNKGRIDLTVKhtpTYTYIYIFEFKylkvkDSDKEKAEEALEQIKEKGYAEKY 80

                          90       100
                  ....*....|....*....|....
gi 498379453  511 KAEGKKIILIGSSFDEEERTIGDW 534
Cdd:pfam08011  81 KGDGKKIKKIGIVFDGKERNIVEE 104
 
Name Accession Description Interval E-value
AAA-ATPase_like pfam09820
Predicted AAA-ATPase; This family contains many hypothetical bacterial proteins. This family ...
 10-296 3.41e-133

Predicted AAA-ATPase; This family contains many hypothetical bacterial proteins. This family was previously the N-terminal part of the Pfam DUF1703 (pfam08011) family before it was split into two. This region is predicted to be an AAA-ATPase domain.


Pssm-ID: 430851  Cd Length: 278  Bit Score: 388.04  E-value: 3.41e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453   10 PIGVQSFEKMRNDKYLYVDKTKYVYNLVCTSSPYFLSRPRRFGKSLFLSTLKAYFLGQKELFKGLYIEKAEekraeiekT 89
Cdd:pfam09820   1 PIGIQSFEEIREEGYYYVDKTAFIYQLVKQGKYYFLSRPRRFGKSLLLSTLEAYFDGKKELFGGLYIGKLP--------T 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453   90 DAWVEYPVLYMDFNIGRYDEPNSLKSHLNIVLSQFEEIYG-ANKQEEEPAQRFAGIVQRAYEKTGKQVVILVDEYDKPLL 168
Cdd:pfam09820  73 DWWNKYPVLRIDFSAGKYDSPDELEERLNRYLSNWEKLFGeTYEDEGSPGGRLAELIRRAYEKTGQQVVVLIDEYDKPIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453  169 QTMGvNEALNEEFRNTLKAFYSVTKTCDQYIRFAFLTGVTKFSKVSIFSDLNNLQDISMLNDYAEICGLTQTEIEKTFKP 248
Cdd:pfam09820 153 DNLS-DEELYREMRDFLRSFYGVLKGLDGYLRFVFLTGVSKFTKDSIFSGLNNLNDITLDPRYSAICGFTEEELETIFDE 231

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 498379453  249 EIERLAtnTKNSYDKMLEELKKRYDGYKFSV-LGESVYNPFSILNTLNS 296
Cdd:pfam09820 232 YLEELA--LPQTYDEMIEELKEWYNGYSFGEdSGESVYNPFSILNFFDK 278
PDDEXK_9 pfam08011
PD-(D/E)XK nuclease superfamily; This family contains many hypothetical bacterial proteins. It ...
 440-534 1.62e-24

PD-(D/E)XK nuclease superfamily; This family contains many hypothetical bacterial proteins. It has been identified as a member of the PD-(D/E)XK nuclease superfamily through transitive meta profile searches. DUF1703 has the predicted secondary structure pattern of the restriction endonuclease-like fold core and contains an additional beta-strand at the C-terminus.


Pssm-ID: 400391  Cd Length: 104  Bit Score: 97.71  E-value: 1.62e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453  440 LREQNYQTAVYLIFKL-MGQFVETEIHCAKGRADCIVH---TKDSIYIFEFK-----LMSAGSADDAIAQIKEKGYASQF 510
Cdd:pfam08011   1 EFEGYYASVFYAYFALsLGYEVIPEDETNKGRIDLTVKhtpTYTYIYIFEFKylkvkDSDKEKAEEALEQIKEKGYAEKY 80

                          90       100
                  ....*....|....*....|....
gi 498379453  511 KAEGKKIILIGSSFDEEERTIGDW 534
Cdd:pfam08011  81 KGDGKKIKKIGIVFDGKERNIVEE 104
 
Name Accession Description Interval E-value
AAA-ATPase_like pfam09820
Predicted AAA-ATPase; This family contains many hypothetical bacterial proteins. This family ...
 10-296 3.41e-133

Predicted AAA-ATPase; This family contains many hypothetical bacterial proteins. This family was previously the N-terminal part of the Pfam DUF1703 (pfam08011) family before it was split into two. This region is predicted to be an AAA-ATPase domain.


Pssm-ID: 430851  Cd Length: 278  Bit Score: 388.04  E-value: 3.41e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453   10 PIGVQSFEKMRNDKYLYVDKTKYVYNLVCTSSPYFLSRPRRFGKSLFLSTLKAYFLGQKELFKGLYIEKAEekraeiekT 89
Cdd:pfam09820   1 PIGIQSFEEIREEGYYYVDKTAFIYQLVKQGKYYFLSRPRRFGKSLLLSTLEAYFDGKKELFGGLYIGKLP--------T 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453   90 DAWVEYPVLYMDFNIGRYDEPNSLKSHLNIVLSQFEEIYG-ANKQEEEPAQRFAGIVQRAYEKTGKQVVILVDEYDKPLL 168
Cdd:pfam09820  73 DWWNKYPVLRIDFSAGKYDSPDELEERLNRYLSNWEKLFGeTYEDEGSPGGRLAELIRRAYEKTGQQVVVLIDEYDKPIL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453  169 QTMGvNEALNEEFRNTLKAFYSVTKTCDQYIRFAFLTGVTKFSKVSIFSDLNNLQDISMLNDYAEICGLTQTEIEKTFKP 248
Cdd:pfam09820 153 DNLS-DEELYREMRDFLRSFYGVLKGLDGYLRFVFLTGVSKFTKDSIFSGLNNLNDITLDPRYSAICGFTEEELETIFDE 231

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 498379453  249 EIERLAtnTKNSYDKMLEELKKRYDGYKFSV-LGESVYNPFSILNTLNS 296
Cdd:pfam09820 232 YLEELA--LPQTYDEMIEELKEWYNGYSFGEdSGESVYNPFSILNFFDK 278
PDDEXK_9 pfam08011
PD-(D/E)XK nuclease superfamily; This family contains many hypothetical bacterial proteins. It ...
 440-534 1.62e-24

PD-(D/E)XK nuclease superfamily; This family contains many hypothetical bacterial proteins. It has been identified as a member of the PD-(D/E)XK nuclease superfamily through transitive meta profile searches. DUF1703 has the predicted secondary structure pattern of the restriction endonuclease-like fold core and contains an additional beta-strand at the C-terminus.


Pssm-ID: 400391  Cd Length: 104  Bit Score: 97.71  E-value: 1.62e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498379453  440 LREQNYQTAVYLIFKL-MGQFVETEIHCAKGRADCIVH---TKDSIYIFEFK-----LMSAGSADDAIAQIKEKGYASQF 510
Cdd:pfam08011   1 EFEGYYASVFYAYFALsLGYEVIPEDETNKGRIDLTVKhtpTYTYIYIFEFKylkvkDSDKEKAEEALEQIKEKGYAEKY 80

                          90       100
                  ....*....|....*....|....
gi 498379453  511 KAEGKKIILIGSSFDEEERTIGDW 534
Cdd:pfam08011  81 KGDGKKIKKIGIVFDGKERNIVEE 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH