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MULTISPECIES: penicillin-binding protein 2 [Enterococcus]
Protein Classification
peptidoglycan D,D-transpeptidase FtsI family protein ( domain architecture ID 11433609 )
peptidoglycan D,D-transpeptidase FtsI (penicillin-binding protein (PBP) 2) family protein is a membrane-associated enzyme that is most likely involved in the synthesis of cross-linked peptidoglycan
List of domain hits
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
19-711
3.57e-120
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 371.08
E-value: 3.57e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 19 SQRGR K PHIPF RL N LLF FVIFT LF VS L IV RL G YLQ I VEG E E FNKKITA N SSLQITT P S PRG Q IYD SQ G K VL VS N KANLAI 98
Cdd:COG0768 2 KRKKE K RLFRR RL L LLF LLVLL LF LL L VG RL F YLQ V VEG D E YAELAEE N RIRTVPI P A PRG L IYD RN G N VL AT N VPVYSL 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 99 TYTRGKN ieg KD ILPI A N K VNE L INVPVD pnltdrdkkdywlanpenlkaaqsrltdqdkedekgnkitdegtlyakave 178
Cdd:COG0768 82 YADPEEV --- KD PEET A E K LAK L LGLDPE --------------------------------------------------- 107
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 179 kvtpeeiafddrtlqav TIF K RMNAA S QMNTVFIK N eg VTEG E I A T I ge HTAEIS GV STGTDWT R D Y SQSGALRSL LG T V 258
Cdd:COG0768 108 ----------------- ELR K KLKKK S RFPVYLKR N -- LSPE E A A R I -- RALKLP GV YVEAEYK R Y Y PYGELAAHV LG Y V 166
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 259 STEK qglpaeevdeylkkgya RN D RV G T S Y LEK Q YED V L Q G KKA K SE V VL D NN G KIVSQTPIS K - GEK G SN L K LTIDS NF 337
Cdd:COG0768 167 GEIN ----------------- GG D GI G K S G LEK A YED L L R G TPG K RR V EV D AR G RVIRDLGEE K p PVP G KD L V LTIDS DL 229
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 338 Q NKVD E I L Q rnys QI V KTIGP ys ENAY VV A M N P Q TG A ILAM S --- G F H hdlatgevt PN ----- P LA P IL N SE V ----- P 404
Cdd:COG0768 230 Q KIAE E A L K ---- KA V EEYKA -- KSGA VV V M D P K TG E ILAM A syp S F D --------- PN lfvgg P DE P LR N RA V qgtye P 294
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 405 GS VV K AG T LT A GY E T GVI KGNDVLTDEAILLA G SNPKAS W WNASG GT tmq LT AEQ AL EY SSN AYMM KL VFKM mgvnyypn 484
Cdd:COG0768 295 GS TF K PF T AA A AL E E GVI TPDTTFDCPGYYRV G GRTIRD W DRGGH GT --- LT LTE AL AK SSN VGFY KL ALRL -------- 363
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 485 mifpyev G D D TVFKE L R K afae Y G M G T KTGID I PGE TT G I qnkd FKDSSSA p QG G NLLDL S F GQ YDTYSA LQLAQ YVSTV 564
Cdd:COG0768 364 ------- G I D KLYDY L K K ---- F G L G Q KTGID L PGE AS G L ---- LPSPKRW - YP G ETATM S I GQ GLSVTP LQLAQ AYAAI 427
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 565 AN N G IR V Q PH V V EG I YGN D engal G KIL KE i EP K VL NK V n IS EDQIGILQQ G FYN VVN G ts P FT TAR GLKSDKFSI A A KT 644
Cdd:COG0768 428 AN G G VL V K PH L V KE I VDP D ----- G EVV KE - EP E VL RR V - IS PETAETVRE G MEG VVN E -- P GG TAR RAAIPGYRV A G KT 498
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 498393127 645 GTA ETQATDAN G VNHTTVNSNL V AY AP YE NP EI A IS VV L -- P HLNDEASKPNQTIAK E VL EAY MEMYKK 711
Cdd:COG0768 499 GTA QVVDIGNG G YYKGRHIASF V GF AP AD NP RY A VA VV V en P GGGAYGGTVAAPVFR E IM EAY LRLLGP 567
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
19-711
3.57e-120
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 371.08
E-value: 3.57e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 19 SQRGR K PHIPF RL N LLF FVIFT LF VS L IV RL G YLQ I VEG E E FNKKITA N SSLQITT P S PRG Q IYD SQ G K VL VS N KANLAI 98
Cdd:COG0768 2 KRKKE K RLFRR RL L LLF LLVLL LF LL L VG RL F YLQ V VEG D E YAELAEE N RIRTVPI P A PRG L IYD RN G N VL AT N VPVYSL 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 99 TYTRGKN ieg KD ILPI A N K VNE L INVPVD pnltdrdkkdywlanpenlkaaqsrltdqdkedekgnkitdegtlyakave 178
Cdd:COG0768 82 YADPEEV --- KD PEET A E K LAK L LGLDPE --------------------------------------------------- 107
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 179 kvtpeeiafddrtlqav TIF K RMNAA S QMNTVFIK N eg VTEG E I A T I ge HTAEIS GV STGTDWT R D Y SQSGALRSL LG T V 258
Cdd:COG0768 108 ----------------- ELR K KLKKK S RFPVYLKR N -- LSPE E A A R I -- RALKLP GV YVEAEYK R Y Y PYGELAAHV LG Y V 166
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 259 STEK qglpaeevdeylkkgya RN D RV G T S Y LEK Q YED V L Q G KKA K SE V VL D NN G KIVSQTPIS K - GEK G SN L K LTIDS NF 337
Cdd:COG0768 167 GEIN ----------------- GG D GI G K S G LEK A YED L L R G TPG K RR V EV D AR G RVIRDLGEE K p PVP G KD L V LTIDS DL 229
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 338 Q NKVD E I L Q rnys QI V KTIGP ys ENAY VV A M N P Q TG A ILAM S --- G F H hdlatgevt PN ----- P LA P IL N SE V ----- P 404
Cdd:COG0768 230 Q KIAE E A L K ---- KA V EEYKA -- KSGA VV V M D P K TG E ILAM A syp S F D --------- PN lfvgg P DE P LR N RA V qgtye P 294
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 405 GS VV K AG T LT A GY E T GVI KGNDVLTDEAILLA G SNPKAS W WNASG GT tmq LT AEQ AL EY SSN AYMM KL VFKM mgvnyypn 484
Cdd:COG0768 295 GS TF K PF T AA A AL E E GVI TPDTTFDCPGYYRV G GRTIRD W DRGGH GT --- LT LTE AL AK SSN VGFY KL ALRL -------- 363
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 485 mifpyev G D D TVFKE L R K afae Y G M G T KTGID I PGE TT G I qnkd FKDSSSA p QG G NLLDL S F GQ YDTYSA LQLAQ YVSTV 564
Cdd:COG0768 364 ------- G I D KLYDY L K K ---- F G L G Q KTGID L PGE AS G L ---- LPSPKRW - YP G ETATM S I GQ GLSVTP LQLAQ AYAAI 427
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 565 AN N G IR V Q PH V V EG I YGN D engal G KIL KE i EP K VL NK V n IS EDQIGILQQ G FYN VVN G ts P FT TAR GLKSDKFSI A A KT 644
Cdd:COG0768 428 AN G G VL V K PH L V KE I VDP D ----- G EVV KE - EP E VL RR V - IS PETAETVRE G MEG VVN E -- P GG TAR RAAIPGYRV A G KT 498
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 498393127 645 GTA ETQATDAN G VNHTTVNSNL V AY AP YE NP EI A IS VV L -- P HLNDEASKPNQTIAK E VL EAY MEMYKK 711
Cdd:COG0768 499 GTA QVVDIGNG G YYKGRHIASF V GF AP AD NP RY A VA VV V en P GGGAYGGTVAAPVFR E IM EAY LRLLGP 567
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
29-706
2.02e-84
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 278.25
E-value: 2.02e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 29 F R LNL L FFVIFT LF VS L IV RL G YLQ IVE GEE FNKKITA N SSLQITT P S PRG Q I Y D SQ G KV L VS N KANLAITYTRG K nieg 108
Cdd:TIGR03423 1 R R ALV L GGLVLA LF GV L AA RL F YLQ VIR GEE YATLSED N RIRLVPI P P PRG L I L D RN G VL L AD N RPSFSLEIVPE K ---- 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 109 kdilpiankvnelinvpvdpnltdrdkkdywlan PEN L K A AQS RL T dqdkedekgn K IT D egtlyakavek VT PE E IA fd 188
Cdd:TIGR03423 77 ---------------------------------- VDD L D A TLD RL A ---------- K LL D ----------- LD PE D IA -- 99
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 189 drtlqav TIF K RMNAASQMNTVFI K n EGV TE G E I A TIGEHTAEIS GV STGTDWT R D Y SQSGALRSL LG T V S -- T E KQ glp 266
Cdd:TIGR03423 100 ------- RFL K ELKRSRRFEPIPL K - SDL TE E E V A RFAVNQYRLP GV EIEARLK R Y Y PYGELAAHV LG Y V G ei N E ED --- 168
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 267 A E EVDE ylk KG YA RN D RV G T S YL EK Q YED V L Q GK KAKS EV VLDNN G KIVSQTPISKGEK G SN L K LTID SNF Q NKVDEI L q 346
Cdd:TIGR03423 169 L E RLEP --- AN YA GG D YI G K S GI EK Y YED E L R GK PGYR EV EVNAR G RVIRTLSRVPPVP G KD L V LTID ARL Q QAAEKA L - 244
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 347 rnysqivkti G PYS en AY VV A M N P Q TG A ILAM - S -- G F HHD L ATGEVTP -------- N P LA P I LN SEV ----- PGS VV K A 410
Cdd:TIGR03423 245 ---------- G GRR -- GA VV V M D P R TG E ILAM v S tp S F DPN L FVDGISS kdykalln D P DR P L LN RAI qgvyp PGS TF K P 312
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 411 GTLT A GY E T GVI KGNDVLTD eaill A G SN -- PKASW -- W NAS G - G T tmq LTAEQ A L E Y S SNA Y mmklv F KMMG vnyypnm 485
Cdd:TIGR03423 313 VVAL A AL E E GVI TPETRIYC ----- P G YF ql GGRRF rc W KRG G h G R --- VDLRK A I E E S CDV Y ----- F YQLA ------- 372
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 486 ifp YEV G D D TVFKELRK afae Y G M G T KTGID I PGE TT G I ------ QN K D F KDSS sap QG G NL L DL S F GQ - Y DTYSA LQLA 558
Cdd:TIGR03423 373 --- LRL G I D KIAEYAKR ---- F G F G Q KTGID L PGE KS G L vpsrew KR K R F GQPW --- YP G DT L NV S I GQ g Y VLVTP LQLA 442
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 559 QYVSTV AN N G IRVQ PH V V EG I YGN D engal G KILKEI EP K VL NKVN IS EDQIGILQQ G FYN VVNG ts P FT TAR GLKSDK - 637
Cdd:TIGR03423 443 VATAAL AN G G KLYK PH L V KS I EDP D ----- G GVVRRT EP E VL RPLP IS PENLDVVRE G MRD VVNG -- P GG TAR RARLGL p 515
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 498393127 638 FSI A A KTGTA E ------ TQAT DA NGVN - HTTVNSNL VA Y APY E NP E IA IS V VLP H LN -- DE A SK P nqt IA KEVLE AY M 706
Cdd:TIGR03423 516 YKM A G KTGTA Q vvslkq GEKY DA EQIP e RLRDHALF VA F APY D NP K IA VA V IVE H GG gg SS A AA P --- IA RKIMD AY L 590
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
363-703
1.57e-59
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 202.65
E-value: 1.57e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 363 AYV V AMN P Q TG AI LAM S G FHHDLAT G EVT P NPLAPILNSEV PGS VV K AG T LT A GYET GV I K GNDVLT D EAILLA G SNPKA 442
Cdd:pfam00905 1 GSA V VLD P K TG EV LAM V G KPSYDPN G FIG P LRNRAVTSRYE PGS TF K PF T AL A ALDN GV L K PDETIF D WPGKQQ G GKSIG 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 443 S W wna SGGTTMQL T AE QALEYSSN A YM M KL VF K M mgvnyypnmifpyev G D D T vfke LR KAFAEY G M G T KTGI DI PGE TT 522
Cdd:pfam00905 81 D W --- NQDQVGIG T LR QALEYSSN W YM Q KL AQ K L --------------- G A D K ---- LR SYLKKF G Y G N KTGI GL PGE NA 138
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 523 G IQNKDFKDSSS A pqggnlldl SFG QYD T YSA LQ L AQ YVSTV AN N G IR V Q PH V V EG I YG ndengalgkilk EIE PKVLNK 602
Cdd:pfam00905 139 G YLTPYWLEGAT A --------- SFG IGL T ITP LQ Q AQ AYAAI AN G G KL V P PH L V KS I ED ------------ KVD PKVLNK 197
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 603 VN IS EDQIGILQQGFYN VVN GTSPFT TA R glk SDKFSI A A KTGTA ETQATDAN G VNHTTVNSNL V A YAP YE NP EI A IS V V 682
Cdd:pfam00905 198 LP IS KSTAEKVKDMLRL VVN DGTGTG TA A --- VPGYKV A G KTGTA QVAGPKGG G YYDGAQIGWF V G YAP AD NP KY A FA V L 274
330 340
....*....|....*....|..
gi 498393127 683 LPHLNDEA - S K PNQT I A K EV LE 703
Cdd:pfam00905 275 IDDPKRYY g G K VAAP I F K DI LE 296
PRK10795
PRK10795 penicillin-binding protein 2; Provisional
35-706
4.41e-29
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain]
Cd Length: 634
Bit Score: 122.95
E-value: 4.41e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 35 F FV I FT L FVS LI VR L GY LQIV EGEEFNKKITA N SSLQITTPSP RG Q IYD SQ G KV L VS N KA nlaitytrgkn I EGKDIL P i 114
Cdd:PRK10795 26 F LG I LL L TGV LI AN L YN LQIV RFTDYQTRSNE N RIKLVPIAPS RG I IYD RN G TP L AL N RT ----------- I YQLEMM P - 93
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 115 a N KV NE L invpvdpnltdrdkkdywlan PEN L K A AQ S -- R LTD Q D KED ekgnkitdegtlyakavekvtpeeiafddrtl 192
Cdd:PRK10795 94 - E KV DN L --------------------- QQT L D A LR S vv D LTD D D IAA -------------------------------- 119
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 193 qavti F KRMN A A S QMN T VFIKNEGV TE GEI A TIGEHTAEIS GV STGTDWT R D Y SQSG AL RSLL G T VS T ekqg LPAEE V DE 272
Cdd:PRK10795 120 ----- F RKER A R S RRF T SIPVKTNL TE VQV A RFAVNQYRFP GV EVKGYQR R Y Y PYGS AL THVI G Y VS K ---- INDKD V ER 190
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 273 YL K K G ---- YA RNDRV G TSYL E KQ YEDVL Q GK KAKS EV VLD N N G KIVS Q TPISKGEK G SNLK LT I D SNF Q NKVDEI L QRN 348
Cdd:PRK10795 191 LD K E G klan YA ATHDI G KLGI E RY YEDVL H GK TGYE EV EVN N R G RVIR Q LHEQPPQA G HDIY LT L D LKL Q QYIETL L AGS 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 349 ysqivktigpyse N A Y VV AMN P Q TG A ILA M --- SGFHHD L ATGEVTP -------- N P LA P IL N SEV ----- P G S V VK AGT 412
Cdd:PRK10795 271 ------------- R A A VV VTD P R TG G ILA L vst PSYDPN L FVDGISS kdysglln D P NR P LI N RAT qgvyp P A S T VK PYV 337
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 413 LTAGYET GVI KG N DV L T D EAIL - L A GS NPKASW W NAS G GTTMQL T ae QA LE Y S SNAYM mklvfkmmgvnyypnmifp Y E V 491
Cdd:PRK10795 338 AVSALSA GVI TR N TS L F D PGWW q L P GS EKRYRD W KKW G HGRLNV T -- KS LE E S ADTFF ------------------- Y Q V 396
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 492 GD D TVFKE L RKAFAEY G M G TK TGID IPG E TT G I --- QNKDF K DSSSAPQG G NLLDLSF GQ - Y D T YSAL Q LAQYVS T VA N N 567
Cdd:PRK10795 397 AY D MGIDR L SEWMGKF G Y G HY TGID LAE E RS G N mpt REWKQ K RFKKPWYQ G DTIPVGI GQ g Y W T ATPI Q MSKALM T LI N D 476
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 568 GI RVQ PH V veg IYGND E N G ALGKILKEI EP K V lnk VN I SEDQIG I LQQ G F Y N V V N gt S P FT TA RGLKSDK - FS IAAK T GT 646
Cdd:PRK10795 477 GI VKV PH L --- LMSTA E D G KQVPWVQPH EP P V --- GD I HSGYWE I AKD G M Y G V A N -- R P NG TA HKYFASA p YK IAAK S GT 548
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 498393127 647 A ETQATD AN GV - N HTTVNSN L ------ V A Y APY E NP EI A ISVV L P hl N DE A SKPNQ TI AKEV L EAY M 706
Cdd:PRK10795 549 A QVFGLK AN ET y N AHKIAER L rdhklm T A F APY N NP QV A VAII L E -- N GG A GPAVG TI MRQI L DHI M 613
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
19-711
3.57e-120
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 371.08
E-value: 3.57e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 19 SQRGR K PHIPF RL N LLF FVIFT LF VS L IV RL G YLQ I VEG E E FNKKITA N SSLQITT P S PRG Q IYD SQ G K VL VS N KANLAI 98
Cdd:COG0768 2 KRKKE K RLFRR RL L LLF LLVLL LF LL L VG RL F YLQ V VEG D E YAELAEE N RIRTVPI P A PRG L IYD RN G N VL AT N VPVYSL 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 99 TYTRGKN ieg KD ILPI A N K VNE L INVPVD pnltdrdkkdywlanpenlkaaqsrltdqdkedekgnkitdegtlyakave 178
Cdd:COG0768 82 YADPEEV --- KD PEET A E K LAK L LGLDPE --------------------------------------------------- 107
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 179 kvtpeeiafddrtlqav TIF K RMNAA S QMNTVFIK N eg VTEG E I A T I ge HTAEIS GV STGTDWT R D Y SQSGALRSL LG T V 258
Cdd:COG0768 108 ----------------- ELR K KLKKK S RFPVYLKR N -- LSPE E A A R I -- RALKLP GV YVEAEYK R Y Y PYGELAAHV LG Y V 166
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 259 STEK qglpaeevdeylkkgya RN D RV G T S Y LEK Q YED V L Q G KKA K SE V VL D NN G KIVSQTPIS K - GEK G SN L K LTIDS NF 337
Cdd:COG0768 167 GEIN ----------------- GG D GI G K S G LEK A YED L L R G TPG K RR V EV D AR G RVIRDLGEE K p PVP G KD L V LTIDS DL 229
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 338 Q NKVD E I L Q rnys QI V KTIGP ys ENAY VV A M N P Q TG A ILAM S --- G F H hdlatgevt PN ----- P LA P IL N SE V ----- P 404
Cdd:COG0768 230 Q KIAE E A L K ---- KA V EEYKA -- KSGA VV V M D P K TG E ILAM A syp S F D --------- PN lfvgg P DE P LR N RA V qgtye P 294
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 405 GS VV K AG T LT A GY E T GVI KGNDVLTDEAILLA G SNPKAS W WNASG GT tmq LT AEQ AL EY SSN AYMM KL VFKM mgvnyypn 484
Cdd:COG0768 295 GS TF K PF T AA A AL E E GVI TPDTTFDCPGYYRV G GRTIRD W DRGGH GT --- LT LTE AL AK SSN VGFY KL ALRL -------- 363
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 485 mifpyev G D D TVFKE L R K afae Y G M G T KTGID I PGE TT G I qnkd FKDSSSA p QG G NLLDL S F GQ YDTYSA LQLAQ YVSTV 564
Cdd:COG0768 364 ------- G I D KLYDY L K K ---- F G L G Q KTGID L PGE AS G L ---- LPSPKRW - YP G ETATM S I GQ GLSVTP LQLAQ AYAAI 427
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 565 AN N G IR V Q PH V V EG I YGN D engal G KIL KE i EP K VL NK V n IS EDQIGILQQ G FYN VVN G ts P FT TAR GLKSDKFSI A A KT 644
Cdd:COG0768 428 AN G G VL V K PH L V KE I VDP D ----- G EVV KE - EP E VL RR V - IS PETAETVRE G MEG VVN E -- P GG TAR RAAIPGYRV A G KT 498
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 498393127 645 GTA ETQATDAN G VNHTTVNSNL V AY AP YE NP EI A IS VV L -- P HLNDEASKPNQTIAK E VL EAY MEMYKK 711
Cdd:COG0768 499 GTA QVVDIGNG G YYKGRHIASF V GF AP AD NP RY A VA VV V en P GGGAYGGTVAAPVFR E IM EAY LRLLGP 567
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
29-706
2.02e-84
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 278.25
E-value: 2.02e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 29 F R LNL L FFVIFT LF VS L IV RL G YLQ IVE GEE FNKKITA N SSLQITT P S PRG Q I Y D SQ G KV L VS N KANLAITYTRG K nieg 108
Cdd:TIGR03423 1 R R ALV L GGLVLA LF GV L AA RL F YLQ VIR GEE YATLSED N RIRLVPI P P PRG L I L D RN G VL L AD N RPSFSLEIVPE K ---- 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 109 kdilpiankvnelinvpvdpnltdrdkkdywlan PEN L K A AQS RL T dqdkedekgn K IT D egtlyakavek VT PE E IA fd 188
Cdd:TIGR03423 77 ---------------------------------- VDD L D A TLD RL A ---------- K LL D ----------- LD PE D IA -- 99
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 189 drtlqav TIF K RMNAASQMNTVFI K n EGV TE G E I A TIGEHTAEIS GV STGTDWT R D Y SQSGALRSL LG T V S -- T E KQ glp 266
Cdd:TIGR03423 100 ------- RFL K ELKRSRRFEPIPL K - SDL TE E E V A RFAVNQYRLP GV EIEARLK R Y Y PYGELAAHV LG Y V G ei N E ED --- 168
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 267 A E EVDE ylk KG YA RN D RV G T S YL EK Q YED V L Q GK KAKS EV VLDNN G KIVSQTPISKGEK G SN L K LTID SNF Q NKVDEI L q 346
Cdd:TIGR03423 169 L E RLEP --- AN YA GG D YI G K S GI EK Y YED E L R GK PGYR EV EVNAR G RVIRTLSRVPPVP G KD L V LTID ARL Q QAAEKA L - 244
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 347 rnysqivkti G PYS en AY VV A M N P Q TG A ILAM - S -- G F HHD L ATGEVTP -------- N P LA P I LN SEV ----- PGS VV K A 410
Cdd:TIGR03423 245 ---------- G GRR -- GA VV V M D P R TG E ILAM v S tp S F DPN L FVDGISS kdykalln D P DR P L LN RAI qgvyp PGS TF K P 312
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 411 GTLT A GY E T GVI KGNDVLTD eaill A G SN -- PKASW -- W NAS G - G T tmq LTAEQ A L E Y S SNA Y mmklv F KMMG vnyypnm 485
Cdd:TIGR03423 313 VVAL A AL E E GVI TPETRIYC ----- P G YF ql GGRRF rc W KRG G h G R --- VDLRK A I E E S CDV Y ----- F YQLA ------- 372
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 486 ifp YEV G D D TVFKELRK afae Y G M G T KTGID I PGE TT G I ------ QN K D F KDSS sap QG G NL L DL S F GQ - Y DTYSA LQLA 558
Cdd:TIGR03423 373 --- LRL G I D KIAEYAKR ---- F G F G Q KTGID L PGE KS G L vpsrew KR K R F GQPW --- YP G DT L NV S I GQ g Y VLVTP LQLA 442
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 559 QYVSTV AN N G IRVQ PH V V EG I YGN D engal G KILKEI EP K VL NKVN IS EDQIGILQQ G FYN VVNG ts P FT TAR GLKSDK - 637
Cdd:TIGR03423 443 VATAAL AN G G KLYK PH L V KS I EDP D ----- G GVVRRT EP E VL RPLP IS PENLDVVRE G MRD VVNG -- P GG TAR RARLGL p 515
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 498393127 638 FSI A A KTGTA E ------ TQAT DA NGVN - HTTVNSNL VA Y APY E NP E IA IS V VLP H LN -- DE A SK P nqt IA KEVLE AY M 706
Cdd:TIGR03423 516 YKM A G KTGTA Q vvslkq GEKY DA EQIP e RLRDHALF VA F APY D NP K IA VA V IVE H GG gg SS A AA P --- IA RKIMD AY L 590
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
363-703
1.57e-59
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 202.65
E-value: 1.57e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 363 AYV V AMN P Q TG AI LAM S G FHHDLAT G EVT P NPLAPILNSEV PGS VV K AG T LT A GYET GV I K GNDVLT D EAILLA G SNPKA 442
Cdd:pfam00905 1 GSA V VLD P K TG EV LAM V G KPSYDPN G FIG P LRNRAVTSRYE PGS TF K PF T AL A ALDN GV L K PDETIF D WPGKQQ G GKSIG 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 443 S W wna SGGTTMQL T AE QALEYSSN A YM M KL VF K M mgvnyypnmifpyev G D D T vfke LR KAFAEY G M G T KTGI DI PGE TT 522
Cdd:pfam00905 81 D W --- NQDQVGIG T LR QALEYSSN W YM Q KL AQ K L --------------- G A D K ---- LR SYLKKF G Y G N KTGI GL PGE NA 138
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 523 G IQNKDFKDSSS A pqggnlldl SFG QYD T YSA LQ L AQ YVSTV AN N G IR V Q PH V V EG I YG ndengalgkilk EIE PKVLNK 602
Cdd:pfam00905 139 G YLTPYWLEGAT A --------- SFG IGL T ITP LQ Q AQ AYAAI AN G G KL V P PH L V KS I ED ------------ KVD PKVLNK 197
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 603 VN IS EDQIGILQQGFYN VVN GTSPFT TA R glk SDKFSI A A KTGTA ETQATDAN G VNHTTVNSNL V A YAP YE NP EI A IS V V 682
Cdd:pfam00905 198 LP IS KSTAEKVKDMLRL VVN DGTGTG TA A --- VPGYKV A G KTGTA QVAGPKGG G YYDGAQIGWF V G YAP AD NP KY A FA V L 274
330 340
....*....|....*....|..
gi 498393127 683 LPHLNDEA - S K PNQT I A K EV LE 703
Cdd:pfam00905 275 IDDPKRYY g G K VAAP I F K DI LE 296
spoVD_pbp
TIGR02214 stage V sporulation protein D; This model describes the spoVD subfamily of homologs of the ...
33-683
2.72e-36
stage V sporulation protein D; This model describes the spoVD subfamily of homologs of the cell division protein FtsI, a penicillin binding protein. This subfamily is restricted to Bacillus subtilis and related Gram-positive species with known or suspected endospore formation capability. In these species, the functional equivalent of FtsI is desginated PBP-2B, a paralog of spoVD. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Sporulation and germination]
Pssm-ID: 131269 [Multi-domain]
Cd Length: 636
Bit Score: 145.34
E-value: 2.72e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 33 LLFFV I FT -- LF VS LI V RL G Y L Q IVE G EEFNKKITANSSLQ I TTPSP RG Q I Y D SQ G K vlvsnka N LA IT ytrg KNIEGK D 110
Cdd:TIGR02214 2 SIHIL I SF ta LF LI LI L RL F Y V Q VFR G SFYKEMAEDQWTRE I PIEAK RG R I L D RN G N ------- E LA VS ---- VSVDRV D 70
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 111 IL P IANKV N elinvpvdpnltd RDK K DYWL AN penl KA A QSRLT D QD K EDEKGN K i TDEGTLY AK AVE K VTPEE iafddr 190
Cdd:TIGR02214 71 LD P ATIRK N ------------- KEP K QREI AN ---- EL A RVLEM D KE K VFKRIT K - KNSPFVS AK LGR K IEKDK ------ 126
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 191 tlqavtifkrmna A SQMNTVFIK negvtegeiatigehtaeis GVS TGT D WT R D Y SQSGA L RSL LG TVSTEKQ GL paeev 270
Cdd:TIGR02214 127 ------------- A EKVRNLKLN -------------------- GVS VSP D SK R Y Y PNGDF L SHV LG FTNSDGR GL ----- 168
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 271 deylkkgyarndrvgt SY LE KQ Y EDV L Q G KKAKSEVVL D N N GKIV -- S Q TPIS K GEK G SN L K LTID S N F Q --- NKVDEIL 345
Cdd:TIGR02214 169 ---------------- EG LE LY Y DKE L R G LPGVRVAEY D A N SLEL py A Q HAYV K PVD G HD L V LTID E N I Q yii EREADKA 232
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 346 Q R NYS qivktigpy SENAYVVA MNP QT G A IL A MS --- GF hh D LA ---- TGEV T PNPLAPILNSEV PGS VV K AG T LT A GY E 418
Cdd:TIGR02214 233 L R ERK --------- PKGVSIIV MNP KN G E IL G MS nrp TY -- D PN dprd KSPD T ARRNRAVSDAYE PGS TF K II T SS A AM E 301
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 419 T G VI K GN D VLT D E - AILLA G SNP K A sw W NA s GG TTM Q l T AEQALEY S S N AYMMK lvfkm M G VN yypnmifpye V G DDTVF 497
Cdd:TIGR02214 302 E G IV K ES D KFY D D g SATVG G KKI K C -- W KP - GG HGS Q - T FPEVVQN S C N PGFIE ----- L G MR ---------- L G AEKLN 362
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 498 KELRK afae Y G M G T KTGID I PGE TT GI Q n KDF K DSSSA pqgg N L LDL SFGQ YD T YSAL QL AQY V ST VAN N G IRV QPH VVE 577
Cdd:TIGR02214 363 NYILA ---- F G F G S KTGID L PGE AA GI L - VPK K KVGPV ---- D L ATI SFGQ AN T VTPI QL MTA V NA VAN G G KLI QPH IMK 433
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 578 G I YGNDE N galg KILKEI EP K V LNK V n I S EDQIGI L QQGFYN VV - N G TS pftta RGLKSDKFSIAA KTGTA ETQATDA n G 656
Cdd:TIGR02214 434 E I SDSQN N ---- AVDQTF EP E V KRQ V - V S KETTQK L RLALET VV s K G SG ----- KNAFIEGYRVGG KTGTA QKVKPNG - G 502
650 660
....*....|....*....|....*..
gi 498393127 657 VNHTTVNSNL V AY AP YEN P EI A IS VV L 683
Cdd:TIGR02214 503 YMEGEYIVSF V GF AP ADD P AV A VL VV V 529
PBP_dimer
pfam03717 Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of ...
73-317
4.64e-35
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerization. The domain forms a largely disordered 'sugar tongs' structure.
Pssm-ID: 427460 [Multi-domain]
Cd Length: 178
Bit Score: 130.91
E-value: 4.64e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 73 TT P S PRG Q IYD SQ G K VL VS NK ANLAI T Y T RG K n IEGK D I L PI A N K VNE L INV pv DPN L T D R D KKDYW lanpenlkaaqsr 152
Cdd:pfam03717 1 PI P A PRG E IYD RN G V VL AT NK PVYSL T I T PS K - LKKA D A L KT A L K LAK L LSN -- YED L D D E D LTERF ------------- 64
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 153 ltdqdkedekgnkitdegtlyakavekvtpeeiafddrtlqavtif KR MN AASQMNT V F IK n EGVT E G E I A T I G E HTA E I 232
Cdd:pfam03717 65 ---------------------------------------------- LK MN SYKSYYP V V IK - KNLS E E E V A R I E E NLL E L 97
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 233 S GVS TG TD WT R D Y SQSGALRS LLG T V STEKQ glpa EE VDE YL K KGY A R N D R VG T S Y LEKQYE D VL Q GK KAKSE V VL D NN G 312
Cdd:pfam03717 98 P GVS IE TD PV R Y Y PYGELAAH LLG Y V GEITE ---- EE LEK YL D KGY S R G D L VG K S G LEKQYE S VL R GK DGVRQ V EV D AL G 173
....*
gi 498393127 313 KIVSQ 317
Cdd:pfam03717 174 RVIRE 178
PRK10795
PRK10795 penicillin-binding protein 2; Provisional
35-706
4.41e-29
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain]
Cd Length: 634
Bit Score: 122.95
E-value: 4.41e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 35 F FV I FT L FVS LI VR L GY LQIV EGEEFNKKITA N SSLQITTPSP RG Q IYD SQ G KV L VS N KA nlaitytrgkn I EGKDIL P i 114
Cdd:PRK10795 26 F LG I LL L TGV LI AN L YN LQIV RFTDYQTRSNE N RIKLVPIAPS RG I IYD RN G TP L AL N RT ----------- I YQLEMM P - 93
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 115 a N KV NE L invpvdpnltdrdkkdywlan PEN L K A AQ S -- R LTD Q D KED ekgnkitdegtlyakavekvtpeeiafddrtl 192
Cdd:PRK10795 94 - E KV DN L --------------------- QQT L D A LR S vv D LTD D D IAA -------------------------------- 119
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 193 qavti F KRMN A A S QMN T VFIKNEGV TE GEI A TIGEHTAEIS GV STGTDWT R D Y SQSG AL RSLL G T VS T ekqg LPAEE V DE 272
Cdd:PRK10795 120 ----- F RKER A R S RRF T SIPVKTNL TE VQV A RFAVNQYRFP GV EVKGYQR R Y Y PYGS AL THVI G Y VS K ---- INDKD V ER 190
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 273 YL K K G ---- YA RNDRV G TSYL E KQ YEDVL Q GK KAKS EV VLD N N G KIVS Q TPISKGEK G SNLK LT I D SNF Q NKVDEI L QRN 348
Cdd:PRK10795 191 LD K E G klan YA ATHDI G KLGI E RY YEDVL H GK TGYE EV EVN N R G RVIR Q LHEQPPQA G HDIY LT L D LKL Q QYIETL L AGS 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 349 ysqivktigpyse N A Y VV AMN P Q TG A ILA M --- SGFHHD L ATGEVTP -------- N P LA P IL N SEV ----- P G S V VK AGT 412
Cdd:PRK10795 271 ------------- R A A VV VTD P R TG G ILA L vst PSYDPN L FVDGISS kdysglln D P NR P LI N RAT qgvyp P A S T VK PYV 337
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 413 LTAGYET GVI KG N DV L T D EAIL - L A GS NPKASW W NAS G GTTMQL T ae QA LE Y S SNAYM mklvfkmmgvnyypnmifp Y E V 491
Cdd:PRK10795 338 AVSALSA GVI TR N TS L F D PGWW q L P GS EKRYRD W KKW G HGRLNV T -- KS LE E S ADTFF ------------------- Y Q V 396
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 492 GD D TVFKE L RKAFAEY G M G TK TGID IPG E TT G I --- QNKDF K DSSSAPQG G NLLDLSF GQ - Y D T YSAL Q LAQYVS T VA N N 567
Cdd:PRK10795 397 AY D MGIDR L SEWMGKF G Y G HY TGID LAE E RS G N mpt REWKQ K RFKKPWYQ G DTIPVGI GQ g Y W T ATPI Q MSKALM T LI N D 476
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 568 GI RVQ PH V veg IYGND E N G ALGKILKEI EP K V lnk VN I SEDQIG I LQQ G F Y N V V N gt S P FT TA RGLKSDK - FS IAAK T GT 646
Cdd:PRK10795 477 GI VKV PH L --- LMSTA E D G KQVPWVQPH EP P V --- GD I HSGYWE I AKD G M Y G V A N -- R P NG TA HKYFASA p YK IAAK S GT 548
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 498393127 647 A ETQATD AN GV - N HTTVNSN L ------ V A Y APY E NP EI A ISVV L P hl N DE A SKPNQ TI AKEV L EAY M 706
Cdd:PRK10795 549 A QVFGLK AN ET y N AHKIAER L rdhklm T A F APY N NP QV A VAII L E -- N GG A GPAVG TI MRQI L DHI M 613
MrcB
COG0744 Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
332-654
3.25e-19
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain]
Cd Length: 630
Bit Score: 91.91
E-value: 3.25e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 332 T I D SNF Q NKVDEILQRN ysqi VKTIG P YSEN A YV V AMN P Q TG AI LAM S G ------ FHHDL AT GEVTP nplapilnsev PG 405
Cdd:COG0744 300 T L D PKL Q KAAEKAVKNV ---- LPEGK P GGLQ A AL V VVD P K TG EV LAM V G grdygk SQFNR AT QAKRQ ----------- PG 364
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 406 S VV K AGTLT A GY E T G v IKGNDVLT DE AILLA G SN -- PK asww N AS G GTTMQL T AEQ AL EY S S N AYMMK L V fkmmgvnyyp 483
Cdd:COG0744 365 S TF K PFVYA A AL E Q G - YTPATTVD DE PVTFP G GG ws PK ---- N YD G RYRGPV T LRE AL AN S L N TPAVR L A ---------- 429
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 484 nmifp Y EVG D D T V FKEL R KA faeygmgtktgidipgett GI QNKDFKDS S S A pqggnlldls F G QYDT y S A L QL A QYVS T 563
Cdd:COG0744 430 ----- Q EVG L D K V VDTA R RL ------------------- GI TSPLDPNP S L A ---------- L G TSEV - S P L EM A SAYA T 474
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 564 V AN N G IR V Q PH VVEGIYGN D engal GK I L K E IE PK V ln KVN IS EDQIGILQQGFYN VV NG tspf T T A R GLKSDKFSI A A K 643
Cdd:COG0744 475 F AN G G VY V E PH AITKVTDA D ----- GK V L Y E AK PK C -- EQV IS PEVAYLMTDMLQD VV TS ---- G T G R AARLPGRPV A G K 543
330
....*....|.
gi 498393127 644 TGT AE t QAT DA 654
Cdd:COG0744 544 TGT TN - DNR DA 553
PRK15105
PRK15105 peptidoglycan synthase FtsI; Provisional
266-683
6.26e-10
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain]
Cd Length: 578
Bit Score: 62.14
E-value: 6.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 266 P AE EV DEY L K k G YARN D RV G TSYL EK QYEDV L Q G KKAKSE V VL D NN G KIVSQTPISKGEKGS NL K L T ID SNF Q NK V deil 345
Cdd:PRK15105 169 P SG EV TAH L I - G FTNV D SQ G IEGV EK SFDKW L T G QPGERI V RK D RY G RVIEDISSTDSQAAH NL A L S ID ERL Q AL V ---- 243
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 346 qrn Y SQIVKTIG - PYS E NAYV V AMNPQ TG AI LAM SG fhhdla TGEVT PN P L A ---------- P I LNSEV PGS V VK AGTLT 414
Cdd:PRK15105 244 --- Y RELNNAVA f NKA E SGSA V LVDVN TG EV LAM AN ------ SPSYN PN N L S gtpkdamrnr A I TDVFE PGS T VK PMVVM 314
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 415 AGYET GV I K G N D VL TDEAILLA G SNP K aswwna SGGTTMQ LT AEQA L EY SSN AYMM KL VFK M mgvnyy P N mifpyevgdd 494
Cdd:PRK15105 315 TALQR GV V K E N S VL NTVPYRIN G HEI K ------ DVARYSE LT LTGV L QK SSN VGVS KL ALA M ------ P S ---------- 372
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 495 tvf KE L RKAFAEY G M G TK T GIDIP GE TT G I -- Q NKDFK D SSS A pqggnll DL SFG QYDTYSA LQLA QYVS T VANN GI --- 569
Cdd:PRK15105 373 --- SA L VDTYSRF G L G KA T NLGLV GE RS G L yp Q KQRWS D IER A ------- TF SFG YGLMVTP LQLA RVYA T IGSY GI yrp 442
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498393127 570 ---- R V Q P H V V - E GIYG ndengalgkilkei E PK V LNK V NIS E DQIGILQQ G FYNVVN G tspfttarglksdk FS IA A KT 644
Cdd:PRK15105 443 lsit K V D P P V P g E RVFP -------------- E SI V RTV V HMM E SVALPGGG G VKAAIK G -------------- YR IA I KT 494
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 498393127 645 GTA ETQAT D ANGV N httvns NLV AY ---- AP YEN P EI A IS VV L 683
Cdd:PRK15105 495 GTA KKVGP D GRYI N ------ KYI AY tagv AP ASQ P RF A LV VV I 531
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
