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Conserved domains on  [gi|498395660|ref|WP_010709223|]
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MULTISPECIES: single-stranded DNA-binding protein [Bacteria]

Protein Classification

single stranded DNA-binding domain-containing protein( domain architecture ID 489)

single stranded DNA-binding domain-containing protein may bind preferentially to single-stranded DNA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPA_2b-aaRSs_OBF_like super family cl09930
Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with ...
 1-150 1.93e-71

Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.; This superfamily includes two oligonucleotide/oligosaccharide binding fold (OBF) domain families. One of these contains the OBF domains of the large (RPA1, 70kDa), middle (RPA2, RPA4, 32kDa) and small (RPA3, 14 kDa) subunits of human heterotrimeric Replication protein A (RPA), and similar domains. RPA is a nuclear single-strand (ss) DNA-binding protein involved in most aspects of DNA metabolism. This family includes the four OBF domains of RPA1 [DNA-binding domain (DBD)-A, DBD-B, DBD-C, and RPA1N], the OBF domain of RPA2 (RPA2 DBD-D), RPA3, and the OBF domain of RPA4. The major DNA binding activity of human RPA and Saccharomyces cerevisiae RPA appears to be associated with DBD-A and -B, of RPA1. RPA1 DBD-C shows only weak ssDNA-binding activity and is involved in trimerization. The other OBF domain family in this superfamily is the N-terminal, anticodon recognition domain of class 2b aminoacyl-tRNA synthetases (aaRSs). aaRSs catalyze the specific attachment of amino acids to their cognate tRNAs during protein biosynthesis. Class 2b aaRSs include the homodimeric aspartyl-, asparaginyl-, and lysyl-tRNA synthetases.


The actual alignment was detected with superfamily member PRK07275:

Pssm-ID: 471953 [Multi-domain]  Cd Length: 162  Bit Score: 211.67  E-value: 1.93e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   1 MINNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTR 80
Cdd:PRK07275   1 MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINCVIWRQQAENLANWAKKGALIGVTGRIQTR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  81 NYENQQGQRIYVTEVVVESFQLLESKEVSQQRGVNASN------PTPVGQQASNAQQP------FPDLEGSSIDISDDDL 148
Cdd:PRK07275  81 NYENQQGQRVYVTEVVADNFQMLESRATREGGSGGSYNggfnnaPSANSYSAPAQQTPnfgrdeSPFGNSNPMDISDDDL 160


                 ..
gi 498395660 149 PF 150
Cdd:PRK07275 161 PF 162
 
Name Accession Description Interval E-value
PRK07275 PRK07275
single-stranded DNA-binding protein; Provisional
 1-150 1.93e-71

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180915 [Multi-domain]  Cd Length: 162  Bit Score: 211.67  E-value: 1.93e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   1 MINNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTR 80
Cdd:PRK07275   1 MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINCVIWRQQAENLANWAKKGALIGVTGRIQTR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  81 NYENQQGQRIYVTEVVVESFQLLESKEVSQQRGVNASN------PTPVGQQASNAQQP------FPDLEGSSIDISDDDL 148
Cdd:PRK07275  81 NYENQQGQRVYVTEVVADNFQMLESRATREGGSGGSYNggfnnaPSANSYSAPAQQTPnfgrdeSPFGNSNPMDISDDDL 160


                 ..
gi 498395660 149 PF 150
Cdd:PRK07275 161 PF 162
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 1-150 3.78e-50

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 157.97  E-value: 3.78e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660    1 MINNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGE--READYIQCVIWRKPAETLANYTRKGTLIGLVGRLQ 78
Cdd:TIGR00621   3 MVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQDGEwkEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   79 TRNYENQQGQRIYVTEVVVESFQLLESKEVSQQ-------RGVNASNPTPVGQQASN----AQQPFPDLEGsSIDISDDD 147
Cdd:TIGR00621  83 TRKWEDQNGQKRSKTEIIADNVQLLDLLGARAQggefsggGGSGNRPQGGQEQSATGkdpaQSAPQSGSAD-PIDGDDDE 161


                  ...
gi 498395660  148 LPF 150
Cdd:TIGR00621 162 IPF 164
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
2-113 1.38e-49

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 154.61  E-value: 1.38e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGER--EADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQT 79
Cdd:COG0629    1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKDQDGEWkdETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRT 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 498395660  80 RNYENQQGQRIYVTEVVVESFQLLESKEVSQQRG 113
Cdd:COG0629   81 RSWEDKDGQKRYTTEVVADEIQFLGSRPSGGGGG 114
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 2-103 2.54e-42

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 135.83  E-value: 2.54e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660    2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQ-NGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTR 80
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDRgEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQTR 80

                          90       100
                  ....*....|....*....|...
gi 498395660   81 NYENQQGQRIYVTEVVVESFQLL 103
Cdd:pfam00436  81 KYEDQEGQKRYVTEIVADEVQFL 103
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 5-103 3.40e-38

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 125.42  E-value: 3.40e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   5 VTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQN-GEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTRNYE 83
Cdd:cd04496    1 VILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDRDeEEEETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRSWE 80

                         90       100
                 ....*....|....*....|
gi 498395660  84 NQQGQRIYVTEVVVESFQLL 103
Cdd:cd04496   81 DKDGQKRYGTEVVADRIEFL 100
 
Name Accession Description Interval E-value
PRK07275 PRK07275
single-stranded DNA-binding protein; Provisional
 1-150 1.93e-71

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180915 [Multi-domain]  Cd Length: 162  Bit Score: 211.67  E-value: 1.93e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   1 MINNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTR 80
Cdd:PRK07275   1 MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINCVIWRQQAENLANWAKKGALIGVTGRIQTR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  81 NYENQQGQRIYVTEVVVESFQLLESKEVSQQRGVNASN------PTPVGQQASNAQQP------FPDLEGSSIDISDDDL 148
Cdd:PRK07275  81 NYENQQGQRVYVTEVVADNFQMLESRATREGGSGGSYNggfnnaPSANSYSAPAQQTPnfgrdeSPFGNSNPMDISDDDL 160


                 ..
gi 498395660 149 PF 150
Cdd:PRK07275 161 PF 162
PRK06751 PRK06751
single-stranded DNA-binding protein; Provisional
 1-150 2.42e-55

single-stranded DNA-binding protein; Provisional


Pssm-ID: 168659 [Multi-domain]  Cd Length: 173  Bit Score: 171.52  E-value: 2.42e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   1 MINNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTR 80
Cdd:PRK06751   1 MMNRVILVGRLTKDPDLRYTPNGVAVATFTLAVNRAFANQQGEREADFINCVIWRKQAENVANYLKKGSLAGVDGRLQTR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  81 NYENQQGQRIYVTEVVVESFQLLESKEV-SQQRGVNASNPT----------PVGQQASNAQQ-------------PFPDL 136
Cdd:PRK06751  81 NYEGQDGKRVYVTEVLAESVQFLEPRNGgGEQRGSFNQQPSgagfgnqssnPFGQSSNSGNQgnqgnsgftknddPFSNV 160

                        170
                 ....*....|....
gi 498395660 137 eGSSIDISDDDLPF 150
Cdd:PRK06751 161 -GQPIDISDDDLPF 173
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 1-150 3.78e-50

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 157.97  E-value: 3.78e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660    1 MINNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGE--READYIQCVIWRKPAETLANYTRKGTLIGLVGRLQ 78
Cdd:TIGR00621   3 MVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQDGEwkEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   79 TRNYENQQGQRIYVTEVVVESFQLLESKEVSQQ-------RGVNASNPTPVGQQASN----AQQPFPDLEGsSIDISDDD 147
Cdd:TIGR00621  83 TRKWEDQNGQKRSKTEIIADNVQLLDLLGARAQggefsggGGSGNRPQGGQEQSATGkdpaQSAPQSGSAD-PIDGDDDE 161


                  ...
gi 498395660  148 LPF 150
Cdd:TIGR00621 162 IPF 164
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
2-113 1.38e-49

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 154.61  E-value: 1.38e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGER--EADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQT 79
Cdd:COG0629    1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKDQDGEWkdETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRT 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 498395660  80 RNYENQQGQRIYVTEVVVESFQLLESKEVSQQRG 113
Cdd:COG0629   81 RSWEDKDGQKRYTTEVVADEIQFLGSRPSGGGGG 114
PRK06752 PRK06752
single-stranded DNA-binding protein; Validated
 1-106 2.71e-44

single-stranded DNA-binding protein; Validated


Pssm-ID: 168660  Cd Length: 112  Bit Score: 141.33  E-value: 2.71e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   1 MINNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTR 80
Cdd:PRK06752   1 MMNRVVLIGRLTKEPELYYTKQGVAYARVCVAVNRGFRNSLGEQQVDFINCVVWRKSAENVTEYCTKGSLVGITGRIHTR 80

                         90       100
                 ....*....|....*....|....*.
gi 498395660  81 NYENQQGQRIYVTEVVVESFQLLESK 106
Cdd:PRK06752  81 NYEDDQGKRIYITEVVIESITFLERR 106
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 2-103 2.54e-42

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 135.83  E-value: 2.54e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660    2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQ-NGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTR 80
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDRgEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQTR 80

                          90       100
                  ....*....|....*....|...
gi 498395660   81 NYENQQGQRIYVTEVVVESFQLL 103
Cdd:pfam00436  81 KYEDQEGQKRYVTEIVADEVQFL 103
PRK07274 PRK07274
single-stranded DNA-binding protein; Provisional
 1-120 4.70e-40

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180914  Cd Length: 131  Bit Score: 131.03  E-value: 4.70e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   1 MINNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTR 80
Cdd:PRK07274   1 MYNKVILIGRLTATPELVKTANDKSVARVTLAVNRRFKNQNGEREADFINVVLWGKLAETLASYASKGSLISIDGELRTR 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 498395660  81 NYEnQQGQRIYVTEVVVESFQLLESKevsQQRGVNASNPT 120
Cdd:PRK07274  81 KYE-KDGQTHYVTEVLCQSFQLLESR---AQRAMRENNVG 116
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 5-103 3.40e-38

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 125.42  E-value: 3.40e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   5 VTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQN-GEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTRNYE 83
Cdd:cd04496    1 VILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDRDeEEEETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRSWE 80

                         90       100
                 ....*....|....*....|
gi 498395660  84 NQQGQRIYVTEVVVESFQLL 103
Cdd:cd04496   81 DKDGQKRYGTEVVADRIEFL 100
PRK08486 PRK08486
single-stranded DNA-binding protein; Provisional
 1-150 1.56e-25

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236275 [Multi-domain]  Cd Length: 182  Bit Score: 95.68  E-value: 1.56e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   1 MINNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQNGER--EADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQ 78
Cdd:PRK08486   1 MFNKVILVGNLTRDVELRYLPSGSAIATIGLATSRRFKKQDGEKgeEVCFIDIRLFGRTAEIANQYLSKGSKVLIEGRLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  79 TRNYENQQGQRIYVTEVVVESFQLLESK-----------------------------------EVSQQRGVNASNPTPVG 123
Cdd:PRK08486  81 FESWMDQNGQKRSKHTITAESMQMLDSKsdnpqanamqdnsfhenfnnnypgnynnpsqdpymNQAQSYNQNAYAKENQQ 160

                        170       180
                 ....*....|....*....|....*..
gi 498395660 124 QQASNAQQPFPDlegssIDISDDDLPF 150
Cdd:PRK08486 161 AQPPKYENSVPE-----IDIDEEEIPF 182
PRK06863 PRK06863
single-stranded DNA-binding protein; Provisional
 2-150 6.17e-22

single-stranded DNA-binding protein; Provisional


Pssm-ID: 136097 [Multi-domain]  Cd Length: 168  Bit Score: 86.17  E-value: 6.17e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQN-GERE--ADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQ 78
Cdd:PRK06863   4 INKVIIVGHLGNDPEIRTMPNGEAVANISVATSESWTDKNtGERRevTEWHRIVFYRRQAEVAGEYLRKGSQVYVEGRLK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  79 TRNYENQQGQRIYVTEVVVESFQLLESKEVSQQRGVNASNPTP---VGQQASNAQ------QPFPDLEG----SSIDISD 145
Cdd:PRK06863  84 TRKWQDQNGQDRYTTEIQGDVLQMLGGRNQRNAGGYGNSGPAPqqsYQAGQTNNGnsqqasRPAPQQAApqaePPMDGFD 163


                 ....*
gi 498395660 146 DDLPF 150
Cdd:PRK06863 164 DDIPF 168
PRK07772 PRK07772
single-stranded DNA-binding protein; Provisional
 4-98 9.32e-22

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236092 [Multi-domain]  Cd Length: 186  Bit Score: 85.86  E-value: 9.32e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   4 NVTLVGRLTKDCDLRYTSSGVAVAAFTLA-----VNRNfTNQNGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQ 78
Cdd:PRK07772   6 TITVVGNLTADPELRFTPSGAAVANFTVAstprtFDRQ-TNEWKDGEALFLRCSIWRQAAENVAESLTKGMRVIVTGRLK 84

                         90       100
                 ....*....|....*....|
gi 498395660  79 TRNYENQQGQRIYVTEVVVE 98
Cdd:PRK07772  85 QRSYETREGEKRTVVELEVD 104
PRK07459 PRK07459
single-stranded DNA-binding protein; Provisional
 2-119 8.16e-21

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180986  Cd Length: 121  Bit Score: 81.66  E-value: 8.16e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQngerEADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTRN 81
Cdd:PRK07459   3 LNSVTLVGRAGRDPEVRYFESGSVVCNLTLAVNRRSRDD----EPDWFNLEIWGKTAQVAADYVKKGSLIGITGSLKFDR 78

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 498395660  82 YENQQGQRIYVTEVV-VESFQLLESKEVSQQRGVNASNP 119
Cdd:PRK07459  79 WTDRNTGEDRSKPVIrVDRLELLGSKRDSEGNANPSNSS 117
PRK09010 PRK09010
single-stranded DNA-binding protein; Provisional
 2-150 5.67e-20

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236362 [Multi-domain]  Cd Length: 177  Bit Score: 81.05  E-value: 5.67e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTN-QNGE-RE-ADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQ 78
Cdd:PRK09010   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDkQTGEmKEqTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  79 TRNYENQQGQRIYVTEVVVE---SFQLLESKE----------VSQQRG------VNASNPTPVGQQASNAQQPFPDLEGS 139
Cdd:PRK09010  86 TRKWTDQSGQDRYTTEVVVNvggTMQMLGGRQgggapaggniGGQQQGgwgqpqQPQGGNQFSGGAQSRPQQSAPAAPSN 165

                        170
                 ....*....|..
gi 498395660 140 SIDIS-DDDLPF 150
Cdd:PRK09010 166 EPPMDfDDDIPF 177
PRK05733 PRK05733
single-stranded DNA-binding protein; Provisional
 2-150 2.48e-19

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235585 [Multi-domain]  Cd Length: 172  Bit Score: 79.20  E-value: 2.48e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTN-QNGER--EADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQ 78
Cdd:PRK05733   5 VNKVILVGTCGQDPEVRYLPNGNAVTNLSLATSEQWTDkQSGQKveRTEWHRVSLFGKVAEIAGEYLRKGSQVYIEGKLQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  79 TRNYEnQQGQRIYVTEVVVE---SFQLLESKEVSQQR---GVNASNPTPVGQQASN----------------AQQPFPDL 136
Cdd:PRK05733  85 TREWE-KDGIKRYTTEIVVDmqgTMQLLGGRPQGDDQggqGGGNYNQSAPRQQAQRpqqaaqqqsrpapqqpAPQPAADF 163

                        170
                 ....*....|....
gi 498395660 137 egssiDISDDDLPF 150
Cdd:PRK05733 164 -----DSFDDDIPF 172
PRK13732 PRK13732
single-stranded DNA-binding protein; Provisional
 2-150 2.85e-19

single-stranded DNA-binding protein; Provisional


Pssm-ID: 184284 [Multi-domain]  Cd Length: 175  Bit Score: 79.39  E-value: 2.85e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTN-QNGE--READYIQCVIWRKPAETLANYTRKGTLIGLVGRLQ 78
Cdd:PRK13732   6 INKVILVGRLGKDPEVRYIPNGGAVANLQVATSESWRDkQTGEmrEQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  79 TRNYENQQGQRiYVTEVVVE---SFQLL--------ESKEVSQQRGVNASNPTPVGQQASN------AQQPFPD---LEG 138
Cdd:PRK13732  86 TRSWEDNGITR-YVTEILVKttgTMQMLgrapqqnaQPQPGPQQNGQPQSADATKKGGAKTkgrgrkAAQPEPQpqpPEG 164

                        170
                 ....*....|..
gi 498395660 139 SSIDISdDDLPF 150
Cdd:PRK13732 165 EDYGFS-DDIPF 175
PRK08763 PRK08763
single-stranded DNA-binding protein; Provisional
 2-150 8.08e-17

single-stranded DNA-binding protein; Provisional


Pssm-ID: 181549 [Multi-domain]  Cd Length: 164  Bit Score: 72.66  E-value: 8.08e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVN--RNFTNQNGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQT 79
Cdd:PRK08763   5 INKVILVGNLGNDPDIKYTQSGMTITRISLATTsvRKDREGNTQERTEWHRVKFFGKLGEIAGEYLRKGSQCYIEGSIRY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  80 RNYENQQGQRIYVTEVVVESFQLLESKevSQQRGVNASNPTPVGQQA----------SNAQQPFPDLEGSSI-DISDDDL 148
Cdd:PRK08763  85 DKFTGQDGQERYVTEIVADEMQMLGGR--GEGGGGGGGGIRPQRQPAprqnngqdyaPRRQQPAPQQSAPPMdDFADDDI 162


                 ..
gi 498395660 149 PF 150
Cdd:PRK08763 163 PF 164
PRK06642 PRK06642
single-stranded DNA-binding protein; Provisional
 2-150 1.40e-16

single-stranded DNA-binding protein; Provisional


Pssm-ID: 135984  Cd Length: 152  Bit Score: 71.67  E-value: 1.40e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQ-NGERE--ADYIQCVIWRKP-AETLANYTRKGTLIGLVGRL 77
Cdd:PRK06642   5 LNKVILIGNVGRDPEIRTTGEGKKIINLSLATTETWKDRiTSERKerTEWHRVVIFSEGlVSVVERYVTKGSKLYIEGSL 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 498395660  78 QTRNYENQQGQRIYVTEVVVESFQlleskevSQQRGVNASNPTPVGQQASNAQQPFPDLEGSSIDIS--DDDLPF 150
Cdd:PRK06642  85 QTRKWNDNSGQEKYTTEVVLQNFN-------SQLILLDSKNSNNHNQDSGHSEYKHPETKNHSFDHSdlDDEIPF 152
PRK06958 PRK06958
single-stranded DNA-binding protein; Provisional
 2-103 4.50e-16

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180777 [Multi-domain]  Cd Length: 182  Bit Score: 70.98  E-value: 4.50e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTN-QNGE-REA-DYIQCVIWRKPAETLANYTRKGTLIGLVGRLQ 78
Cdd:PRK06958   4 VNKVILVGNLGADPEVRYLPSGDAVANIRLATTDRYKDkASGEfKEAtEWHRVAFFGRLAEIVGEYLKKGSSVYIEGRIR 83

                         90       100
                 ....*....|....*....|....*
gi 498395660  79 TRNYENQQGQRIYVTEVVVESFQLL 103
Cdd:PRK06958  84 TRKWQGQDGQDRYSTEIVADQMQML 108
PRK06293 PRK06293
single-stranded DNA-binding protein; Provisional
 5-150 3.87e-12

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180517 [Multi-domain]  Cd Length: 161  Bit Score: 60.30  E-value: 3.87e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   5 VTLVGRLTKDCDLRYTSSGVAVAAFTLAVNrnfTNQNGEREADYIQCVIWRKPAETLANYTRKGTLIGLVGRLQTRNYEN 84
Cdd:PRK06293   4 GYIVGRLGADPEERMTSKGKRVVVLRLGVK---SRVGSKDETVWCRCNIWGNRYDKMLPYLKKGSGVIVAGEMSPESYVD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660  85 QQGQRIYVTEVVVES--FQLLESKEVSQQRGVNASNptpvGQQASNAQ------QPFPDLE-----------GSSIDISD 145
Cdd:PRK06293  81 KDGSPQSSLVVSVDTikFSPFGRNEGSRQPSAGEDE----GQQRGYDNvsigfeGESLDTEsaldkdmyagyGQDQQYAS 156


                 ....*
gi 498395660 146 DDLPF 150
Cdd:PRK06293 157 EDVPF 161
PRK06341 PRK06341
single-stranded DNA-binding protein; Provisional
 2-100 2.22e-11

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235782 [Multi-domain]  Cd Length: 166  Bit Score: 58.28  E-value: 2.22e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTNQN-GER--EADYIQCVIWR----KPAEtlaNYTRKGTLIGLV 74
Cdd:PRK06341   5 VNKVILIGNLGADPEIRRTQDGRPIANLRIATSETWRDRNsGERkeKTEWHRVVIFNeglcKVAE---QYLKKGAKVYIE 81

                         90       100
                 ....*....|....*....|....*.
gi 498395660  75 GRLQTRNYENQQGQRIYVTEVVVESF 100
Cdd:PRK06341  82 GQLQTRKWTDQSGVERYSTEVVLQGF 107
tRNA_anti-codon pfam01336
OB-fold nucleic acid binding domain; This family contains OB-fold domains that bind to nucleic ...
 5-103 3.31e-04

OB-fold nucleic acid binding domain; This family contains OB-fold domains that bind to nucleic acids. The family includes the anti-codon binding domain of lysyl, aspartyl, and asparaginyl -tRNA synthetases (See pfam00152). Aminoacyl-tRNA synthetases catalyze the addition of an amino acid to the appropriate tRNA molecule EC:6.1.1.-. This family also includes part of RecG helicase involved in DNA repair. Replication factor A is a hetero-trimeric complex, that contains a subunit in this family. This domain is also found at the C-terminus of bacterial DNA polymerase III alpha chain.


Pssm-ID: 460164 [Multi-domain]  Cd Length: 75  Bit Score: 37.21  E-value: 3.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660    5 VTLVGRLTkdcDLRYTSSGVAVaaFTLavnrnfTNQNGEreadyIQCVIWRKPAETLANYTRKGTLIGLVGRLQTRNYEN 84
Cdd:pfam01336   1 VTVAGRVT---SIRRSGGKLLF--LTL------RDGTGS-----IQVVVFKEEAEKLAKKLKEGDVVRVTGKVKKRKGGE 64

                          90
                  ....*....|....*....
gi 498395660   85 qqgqriyvTEVVVESFQLL 103
Cdd:pfam01336  65 --------LELVVEEIELL 75
PRK05813 PRK05813
single-stranded DNA-binding protein; Provisional
 2-96 1.92e-03

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235616 [Multi-domain]  Cd Length: 219  Bit Score: 36.92  E-value: 1.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498395660   2 INNVTLVGRLTKDCDLRYTSSGVAVAAFTLAVNRNFTnqngerEADYIQCVIWRKPA---ETLanytRKGTLIGLVGRLQ 78
Cdd:PRK05813 109 PNEIFLDGYICKEPVYRTTPFGREIADLLLAVNRPYN------KSDYIPCIAWGRNArfcKTL----EVGDNIRVWGRVQ 178

                         90
                 ....*....|....*...
gi 498395660  79 TRNYEnqqgQRIYVTEVV 96
Cdd:PRK05813 179 SREYQ----KKLSEGEVV 192
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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