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Conserved domains on  [gi|498443515|ref|WP_010749139|]
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MULTISPECIES: PadR family transcriptional regulator [Enterococcus]

Protein Classification

PadR family transcriptional regulator( domain architecture ID 11447737)

PadR family transcriptional regulator similar to the phenolic acid decarboxylation repressor, which is a transcription factor that represses genes associated with the phenolic acid stress response in gram-positive bacteria

Gene Ontology:  GO:0003677|GO:0003700
PubMed:  10679470|10908318|10473770|15808743|8831795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
7-96 4.13e-18

DNA-binding transcriptional regulator, PadR family [Transcription];


:

Pssm-ID: 441301  Cd Length: 102  Bit Score: 72.66  E-value: 4.13e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498443515   7 LPLTETTFYILLVLTT-PAHGYAIIQEIDKLSEGAVKVAAGTMYGAIENLLKLNWIE---EIPSREKRRRVYKITDIGEE 82
Cdd:COG1695    5 LRKGTLELLILALLAEgPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVEsewEESEGGPRRKYYRLTEAGRE 84

                         90
                 ....*....|....
gi 498443515  83 VLKLEIERLRSLIK 96
Cdd:COG1695   85 ELAEWLEEWEKLAE 98
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
7-96 4.13e-18

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 72.66  E-value: 4.13e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498443515   7 LPLTETTFYILLVLTT-PAHGYAIIQEIDKLSEGAVKVAAGTMYGAIENLLKLNWIE---EIPSREKRRRVYKITDIGEE 82
Cdd:COG1695    5 LRKGTLELLILALLAEgPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVEsewEESEGGPRRKYYRLTEAGRE 84

                         90
                 ....*....|....
gi 498443515  83 VLKLEIERLRSLIK 96
Cdd:COG1695   85 ELAEWLEEWEKLAE 98
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 17-96 2.73e-12

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 57.57  E-value: 2.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498443515   17 LLVLTT----PAHGYAIIQEIDKLSEGAVKVAAGTMYGAIENLLKLNWI--EEIPSREKRR-RVYKITDIGEEVLKLEIE 89
Cdd:TIGR03433   7 LLILKTlslgPLHGYGIAQRIQQISEDVLQVEEGSLYPALHRLERRGWIaaEWGESENNRRaKFYRLTAAGRKQLAAETE 86


                  ....*..
gi 498443515   90 RLRSLIK 96
Cdd:TIGR03433  87 SWARLSA 93
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 16-85 4.35e-10

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 51.09  E-value: 4.35e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 498443515   16 ILLVLT-TPAHGYAIIQEIDKLSEGAVKVAAGTMYGAIENLLKLNWIE---EIPSREKRRRVYKITDIGEEVLK 85
Cdd:pfam03551   1 VLAVLGeQPRYGYEIIKELEELSGGFWRPSEGTLYPILKRLEKEGLVEsewVDSGGGPPRKYYRLTDAGRRELA 74
pheS PRK04172
phenylalanine--tRNA ligase subunit alpha;
35-100 3.38e-03

phenylalanine--tRNA ligase subunit alpha;


Pssm-ID: 235239 [Multi-domain]  Cd Length: 489  Bit Score: 35.19  E-value: 3.38e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 498443515  35 KLSEGAVKVAAGTMYGAIENLLKLNWIEEipsREKRRRVYKITDIGEEVLKLEIERLRSLIKLSSE 100
Cdd:PRK04172 141 ALAEGDKEELSEEDLKVLKELKKRKLVEE---KERTERSVELTDAGLELLKEGIELKEEITQLTPE 203
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
7-96 4.13e-18

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 72.66  E-value: 4.13e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498443515   7 LPLTETTFYILLVLTT-PAHGYAIIQEIDKLSEGAVKVAAGTMYGAIENLLKLNWIE---EIPSREKRRRVYKITDIGEE 82
Cdd:COG1695    5 LRKGTLELLILALLAEgPMYGYEIIKELEERSGGFWKVSEGTLYPALKRLEKEGLVEsewEESEGGPRRKYYRLTEAGRE 84

                         90
                 ....*....|....
gi 498443515  83 VLKLEIERLRSLIK 96
Cdd:COG1695   85 ELAEWLEEWEKLAE 98
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 17-96 2.73e-12

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 57.57  E-value: 2.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 498443515   17 LLVLTT----PAHGYAIIQEIDKLSEGAVKVAAGTMYGAIENLLKLNWI--EEIPSREKRR-RVYKITDIGEEVLKLEIE 89
Cdd:TIGR03433   7 LLILKTlslgPLHGYGIAQRIQQISEDVLQVEEGSLYPALHRLERRGWIaaEWGESENNRRaKFYRLTAAGRKQLAAETE 86


                  ....*..
gi 498443515   90 RLRSLIK 96
Cdd:TIGR03433  87 SWARLSA 93
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 16-85 4.35e-10

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 51.09  E-value: 4.35e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 498443515   16 ILLVLT-TPAHGYAIIQEIDKLSEGAVKVAAGTMYGAIENLLKLNWIE---EIPSREKRRRVYKITDIGEEVLK 85
Cdd:pfam03551   1 VLAVLGeQPRYGYEIIKELEELSGGFWRPSEGTLYPILKRLEKEGLVEsewVDSGGGPPRKYYRLTDAGRRELA 74
pheS PRK04172
phenylalanine--tRNA ligase subunit alpha;
35-100 3.38e-03

phenylalanine--tRNA ligase subunit alpha;


Pssm-ID: 235239 [Multi-domain]  Cd Length: 489  Bit Score: 35.19  E-value: 3.38e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 498443515  35 KLSEGAVKVAAGTMYGAIENLLKLNWIEEipsREKRRRVYKITDIGEEVLKLEIERLRSLIKLSSE 100
Cdd:PRK04172 141 ALAEGDKEELSEEDLKVLKELKKRKLVEE---KERTERSVELTDAGLELLKEGIELKEEITQLTPE 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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