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Conserved domains on  [gi|499174263|ref|WP_010871850|]
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MULTISPECIES: ferredoxin [unclassified Synechocystis]

Protein Classification

(2Fe-2S) ferredoxin domain-containing protein( domain architecture ID 10790154)

thioredoxin-like (2Fe-2S) ferredoxin domain-containing protein such as Aquifex aeolicus ferredoxin, 2Fe-2S

CATH:  3.40.30.10
Gene Ontology:  GO:0051536|GO:0051537|GO:0009055|GO:0046872
PubMed:  15558583|10049365
SCOP:  3000113|3000031

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3411 COG3411
2Fe-2S ferredoxin [Energy production and conversion]; 2Fe-2S ferredoxin is part of the Pathway ...
 26-129 6.98e-35

2Fe-2S ferredoxin [Energy production and conversion]; 2Fe-2S ferredoxin is part of the Pathway/BioSystem: 2Fe2S


:

Pssm-ID: 442637  Cd Length: 96  Bit Score: 116.14  E-value: 6.98e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499174263  26 QRHLFLCCDqtkpkCCSKEDSLATWDYLKKRLPELGLDctqssrdGNIFRTKANCLRVCQQGPILLVYPEGIWYRNVTPT 105
Cdd:COG3411    5 RHHVLVCTG-----SCGAAGAEEVLDALKEELKERGLD-------GDVRVTKTGCLGRCEQGPVVVVYPEGVWYGNVTPE 72

                         90       100
                 ....*....|....*....|....
gi 499174263 106 VMEKILQEHILQNRPVEEYRFFTH 129
Cdd:COG3411   73 DVPEIVEEHLLGGRPVERLLLPDP 96
 
Name Accession Description Interval E-value
COG3411 COG3411
2Fe-2S ferredoxin [Energy production and conversion]; 2Fe-2S ferredoxin is part of the Pathway ...
 26-129 6.98e-35

2Fe-2S ferredoxin [Energy production and conversion]; 2Fe-2S ferredoxin is part of the Pathway/BioSystem: 2Fe2S


Pssm-ID: 442637  Cd Length: 96  Bit Score: 116.14  E-value: 6.98e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499174263  26 QRHLFLCCDqtkpkCCSKEDSLATWDYLKKRLPELGLDctqssrdGNIFRTKANCLRVCQQGPILLVYPEGIWYRNVTPT 105
Cdd:COG3411    5 RHHVLVCTG-----SCGAAGAEEVLDALKEELKERGLD-------GDVRVTKTGCLGRCEQGPVVVVYPEGVWYGNVTPE 72

                         90       100
                 ....*....|....*....|....
gi 499174263 106 VMEKILQEHILQNRPVEEYRFFTH 129
Cdd:COG3411   73 DVPEIVEEHLLGGRPVERLLLPDP 96
TRX_Fd_family cd02980
Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX ...
 27-114 2.63e-19

Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE). TRX-like Fds are soluble low-potential electron carriers containing a single [2Fe-2S] cluster. The exact role of TRX-like Fd is still unclear. It has been suggested that it may be involved in nitrogen fixation. Its homologous domains in large redox enzymes (such as Nuo and hydrogenases) function as electron carriers.


Pssm-ID: 239278 [Multi-domain]  Cd Length: 77  Bit Score: 76.13  E-value: 2.63e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499174263  27 RHLFLCCDQtkpkCCSKEDSLATWDYLKKRLPELGLDctqssrdGNIFRTKANCLRVCQQGPILLVYPEGIWYRNVTPTV 106
Cdd:cd02980    1 HHILVCTGT----ACGLRGAEELLEALEKELGIRGGD-------GRVTVERVGCLGACGLAPVVVVYPDGVWYGRVTPED 69


                 ....*...
gi 499174263 107 MEKILQEH 114
Cdd:cd02980   70 VEEIVEEL 77
fdxn_Clost NF041612
2Fe-2S ferredoxin;
28-115 3.11e-13

2Fe-2S ferredoxin;


Pssm-ID: 469496  Cd Length: 102  Bit Score: 61.01  E-value: 3.11e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499174263  28 HLFLCCD-----QTKPKCCSKEdslaTWDYLKKRLPELgldctqSSRD--GNIFRTKANCLRVCQQGPILLVYPEGIWYR 100
Cdd:NF041612   7 HIFVCTScringKQQGFCFSKD----SVDIVSAFMEEI------ESRDlsSEVMVTNTGCFGICNKGPIVVVYPEGVWYG 76

                         90
                 ....*....|....*
gi 499174263 101 NVTPTVMEKILQEHI 115
Cdd:NF041612  77 NVTADDVEEIVESHI 91
Suc_Fer-like pfam06999
Sucrase/ferredoxin-like; This family contains a number of bacterial and eukaryotic proteins ...
 90-125 5.25e-03

Sucrase/ferredoxin-like; This family contains a number of bacterial and eukaryotic proteins approximately 400 residues long that resemble ferredoxin and appear to have sucrolytic activity.


Pssm-ID: 462062 [Multi-domain]  Cd Length: 217  Bit Score: 35.36  E-value: 5.25e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 499174263   90 LLVYPEG-----IWYRNVTPTVMEKILQEHILQNRPVEE-YR 125
Cdd:pfam06999 175 VIIYPPGdagqgIWYGRVTPEHVEGIVEETILKGKVIKElYR 216
 
Name Accession Description Interval E-value
COG3411 COG3411
2Fe-2S ferredoxin [Energy production and conversion]; 2Fe-2S ferredoxin is part of the Pathway ...
 26-129 6.98e-35

2Fe-2S ferredoxin [Energy production and conversion]; 2Fe-2S ferredoxin is part of the Pathway/BioSystem: 2Fe2S


Pssm-ID: 442637  Cd Length: 96  Bit Score: 116.14  E-value: 6.98e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499174263  26 QRHLFLCCDqtkpkCCSKEDSLATWDYLKKRLPELGLDctqssrdGNIFRTKANCLRVCQQGPILLVYPEGIWYRNVTPT 105
Cdd:COG3411    5 RHHVLVCTG-----SCGAAGAEEVLDALKEELKERGLD-------GDVRVTKTGCLGRCEQGPVVVVYPEGVWYGNVTPE 72

                         90       100
                 ....*....|....*....|....
gi 499174263 106 VMEKILQEHILQNRPVEEYRFFTH 129
Cdd:COG3411   73 DVPEIVEEHLLGGRPVERLLLPDP 96
TRX_Fd_family cd02980
Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX ...
 27-114 2.63e-19

Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE). TRX-like Fds are soluble low-potential electron carriers containing a single [2Fe-2S] cluster. The exact role of TRX-like Fd is still unclear. It has been suggested that it may be involved in nitrogen fixation. Its homologous domains in large redox enzymes (such as Nuo and hydrogenases) function as electron carriers.


Pssm-ID: 239278 [Multi-domain]  Cd Length: 77  Bit Score: 76.13  E-value: 2.63e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499174263  27 RHLFLCCDQtkpkCCSKEDSLATWDYLKKRLPELGLDctqssrdGNIFRTKANCLRVCQQGPILLVYPEGIWYRNVTPTV 106
Cdd:cd02980    1 HHILVCTGT----ACGLRGAEELLEALEKELGIRGGD-------GRVTVERVGCLGACGLAPVVVVYPDGVWYGRVTPED 69


                 ....*...
gi 499174263 107 MEKILQEH 114
Cdd:cd02980   70 VEEIVEEL 77
fdxn_Clost NF041612
2Fe-2S ferredoxin;
28-115 3.11e-13

2Fe-2S ferredoxin;


Pssm-ID: 469496  Cd Length: 102  Bit Score: 61.01  E-value: 3.11e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499174263  28 HLFLCCD-----QTKPKCCSKEdslaTWDYLKKRLPELgldctqSSRD--GNIFRTKANCLRVCQQGPILLVYPEGIWYR 100
Cdd:NF041612   7 HIFVCTScringKQQGFCFSKD----SVDIVSAFMEEI------ESRDlsSEVMVTNTGCFGICNKGPIVVVYPEGVWYG 76

                         90
                 ....*....|....*
gi 499174263 101 NVTPTVMEKILQEHI 115
Cdd:NF041612  77 NVTADDVEEIVESHI 91
TRX_Fd_Sucrase cd03062
TRX-like [2Fe-2S] Ferredoxin (Fd) family, Sucrase subfamily; composed of proteins with ...
 26-125 1.18e-03

TRX-like [2Fe-2S] Ferredoxin (Fd) family, Sucrase subfamily; composed of proteins with similarity to a novel plant enzyme, isolated from potato, which contains a Fd-like domain and exhibits sucrolytic activity. The putative active site of the Fd-like domain of the enzyme contains two cysteines and two histidines for possible binding to iron-sulfur clusters, compared to four cysteines present in the active site of Fd.


Pssm-ID: 239360  Cd Length: 97  Bit Score: 36.07  E-value: 1.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499174263  26 QRHLFLCCDQTKPKCCSKedsLAT--WDYLKKRLPELGLDCTQ----SSRDGNIFrtkanclrvcqqGPILLVYP--EGI 97
Cdd:cd03062    1 DPLVLVCTHGKRDKRCGI---CGPplAAELRAELPEHGPGGVRvwevSHVGGHKF------------AGNVIIYPkgDGI 65

                         90       100
                 ....*....|....*....|....*...
gi 499174263  98 WYRNVTPTVMEKILQEHILQNRPVEEYR 125
Cdd:cd03062   66 WYGRVTPEHVPPIVDRLILGGKIIPELR 93
Suc_Fer-like pfam06999
Sucrase/ferredoxin-like; This family contains a number of bacterial and eukaryotic proteins ...
 90-125 5.25e-03

Sucrase/ferredoxin-like; This family contains a number of bacterial and eukaryotic proteins approximately 400 residues long that resemble ferredoxin and appear to have sucrolytic activity.


Pssm-ID: 462062 [Multi-domain]  Cd Length: 217  Bit Score: 35.36  E-value: 5.25e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 499174263   90 LLVYPEG-----IWYRNVTPTVMEKILQEHILQNRPVEE-YR 125
Cdd:pfam06999 175 VIIYPPGdagqgIWYGRVTPEHVEGIVEETILKGKVIKElYR 216
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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