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Conserved domains on  [gi|499201254|ref|WP_010898794|]
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aromatic acid exporter family protein [Alkalihalobacillus halodurans]

Protein Classification

FUSC family protein( domain architecture ID 11467894)

FUSC family protein containing a fusaric acid resistance protein (FUSC_2) domain; may be involved in membrane transport

Gene Ontology:  GO:0055085|GO:0022857|GO:0005886
PubMed:  1370369

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
8-197 3.00e-37

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


:

Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 132.81  E-value: 3.00e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254   8 KHPWIGRRVLKTGLAVCLTTAICMAFNL-SPTFAVISAIVTTEPTAADSLKKGLIRLPAAALGAFFAVLSAYFFGQTPIT 86
Cdd:COG4129    6 ALRRIGLRTLKTALAAALAWLIAELLGLpYPFFAAIAAVLCLQPTVGRSLRRALERILGVLIGALVGVLFFLLLGYGPWQ 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254  87 YAIVSMITIAVCARLRLDAGTLVATLTAVAMIPSTTDHLFADYV-SRVAGTSLGIMISTFVNFMILPPKFGPILMNKVEK 165
Cdd:COG4129   86 LGLAVLLAILLAVLLKLGEGIVLAAVTALLVLLLGSPDDSLGYAlNRLLDTLIGVGVALLVNLLLLPPDPERRLRRAAAE 165
                        170       180       190
                 ....*....|....*....|....*....|..
gi 499201254 166 MFAMLSSELKLVTTKVVDFEKEETMTSYRTLH 197
Cdd:COG4129  166 LLEELADILRELLRLRDASDAEEALKRLRELQ 197
 
Name Accession Description Interval E-value
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
8-197 3.00e-37

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 132.81  E-value: 3.00e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254   8 KHPWIGRRVLKTGLAVCLTTAICMAFNL-SPTFAVISAIVTTEPTAADSLKKGLIRLPAAALGAFFAVLSAYFFGQTPIT 86
Cdd:COG4129    6 ALRRIGLRTLKTALAAALAWLIAELLGLpYPFFAAIAAVLCLQPTVGRSLRRALERILGVLIGALVGVLFFLLLGYGPWQ 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254  87 YAIVSMITIAVCARLRLDAGTLVATLTAVAMIPSTTDHLFADYV-SRVAGTSLGIMISTFVNFMILPPKFGPILMNKVEK 165
Cdd:COG4129   86 LGLAVLLAILLAVLLKLGEGIVLAAVTALLVLLLGSPDDSLGYAlNRLLDTLIGVGVALLVNLLLLPPDPERRLRRAAAE 165
                        170       180       190
                 ....*....|....*....|....*....|..
gi 499201254 166 MFAMLSSELKLVTTKVVDFEKEETMTSYRTLH 197
Cdd:COG4129  166 LLEELADILRELLRLRDASDAEEALKRLRELQ 197
ArAE_1 pfam06081
Aromatic acid exporter family member 1; This family consists of bacterial proteins with three ...
12-150 7.05e-36

Aromatic acid exporter family member 1; This family consists of bacterial proteins with three transmembrane regions that are purported to be aromatic acid exporters.


Pssm-ID: 428756 [Multi-domain]  Cd Length: 141  Bit Score: 127.30  E-value: 7.05e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254   12 IGRRVLKTGLAVCLTTAICMAFNL-SPTFAVISAIVTTEPTAADSLKKGLIRLPAAALGAFFAVLSAYFFGQTPITYAIV 90
Cdd:pfam06081   3 IGYRTLKTAIAVTLAIIIAELLGLpYPVSAGIIAILCIQPTKKRSLRTALARFQACVIGAIIAVVFFELFGYHPFSIGLF 82
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254   91 SMITIAVCARLRLDAGTLVATLTAVAMIPSTTDHlFADYVSRVAGTSLGIMISTFVNFMI 150
Cdd:pfam06081  83 LLLFIPLTVKLKLEEGIVVSSVTVIHLLESKSIS-FFLILNELLLITIGIGVALLVNLYM 141
 
Name Accession Description Interval E-value
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
8-197 3.00e-37

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 132.81  E-value: 3.00e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254   8 KHPWIGRRVLKTGLAVCLTTAICMAFNL-SPTFAVISAIVTTEPTAADSLKKGLIRLPAAALGAFFAVLSAYFFGQTPIT 86
Cdd:COG4129    6 ALRRIGLRTLKTALAAALAWLIAELLGLpYPFFAAIAAVLCLQPTVGRSLRRALERILGVLIGALVGVLFFLLLGYGPWQ 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254  87 YAIVSMITIAVCARLRLDAGTLVATLTAVAMIPSTTDHLFADYV-SRVAGTSLGIMISTFVNFMILPPKFGPILMNKVEK 165
Cdd:COG4129   86 LGLAVLLAILLAVLLKLGEGIVLAAVTALLVLLLGSPDDSLGYAlNRLLDTLIGVGVALLVNLLLLPPDPERRLRRAAAE 165
                        170       180       190
                 ....*....|....*....|....*....|..
gi 499201254 166 MFAMLSSELKLVTTKVVDFEKEETMTSYRTLH 197
Cdd:COG4129  166 LLEELADILRELLRLRDASDAEEALKRLRELQ 197
ArAE_1 pfam06081
Aromatic acid exporter family member 1; This family consists of bacterial proteins with three ...
12-150 7.05e-36

Aromatic acid exporter family member 1; This family consists of bacterial proteins with three transmembrane regions that are purported to be aromatic acid exporters.


Pssm-ID: 428756 [Multi-domain]  Cd Length: 141  Bit Score: 127.30  E-value: 7.05e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254   12 IGRRVLKTGLAVCLTTAICMAFNL-SPTFAVISAIVTTEPTAADSLKKGLIRLPAAALGAFFAVLSAYFFGQTPITYAIV 90
Cdd:pfam06081   3 IGYRTLKTAIAVTLAIIIAELLGLpYPVSAGIIAILCIQPTKKRSLRTALARFQACVIGAIIAVVFFELFGYHPFSIGLF 82
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254   91 SMITIAVCARLRLDAGTLVATLTAVAMIPSTTDHlFADYVSRVAGTSLGIMISTFVNFMI 150
Cdd:pfam06081  83 LLLFIPLTVKLKLEEGIVVSSVTVIHLLESKSIS-FFLILNELLLITIGIGVALLVNLYM 141
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
14-200 2.12e-14

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 72.35  E-value: 2.12e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254  14 RRVLKTGLAVCLTTAICMAFNL-SPTFAVISAIVTTEPTAADSLKKGLIRLPAAALGAFFAVLSAYFFGQTPITYAIVSM 92
Cdd:COG1289   48 RHALRLALAALLALLIALLLGLpHPYWALLTVLIVLQPSYGATLSRALQRILGTLLGALAGLLLLALFPQPLLLLLALAL 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254  93 ITiAVCARLRLD----AGTLVATLTAVAMIPSTTDHLFADYVSRVAGTSLGIMISTFVNFMILPPKFGPILMNKVEKMFA 168
Cdd:COG1289  128 VL-GLCFFALLTrsyaFALAGITAAVVLLFALLGPGVFDVALARVLDTLIGILIALLVSYLLWPRWARRRLRARLARALR 206
                        170       180       190
                 ....*....|....*....|....*....|..
gi 499201254 169 MLSSELKLvttkVVDFEKEETMTSYRTLHHHL 200
Cdd:COG1289  207 ANARYLRA----LLSQGDPADDLALRAARRRL 234
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
16-168 1.83e-09

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 59.22  E-value: 1.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254   16 VLKTGLAVCLTTAICMAFNL-SPTFAVISAIVTTEPTAADSLKKGLIRLPAAALGAFFAVLSAYFFGQTPITYAIVSMIT 94
Cdd:pfam04632   4 ALKTFLAAMLALYIALRLELpQPYWAMTTVFIVSQPLSGAVLSKSFYRLLGTLVGAAAAVLLVALFVQAPLLFLLALALW 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254   95 IAVCARLRLDAGTLVA--------TLTAVAmIPSTTD--HLFADYVSRVAGTSLGIMISTFVNFMILPPKFGPILMNKVE 164
Cdd:pfam04632  84 IGLCLALSLLDRNFRSyafvlagyTAAIIG-LPAVADpeAIFDIAVARVSEISLGILCAALVSALVFPRSVGPALRARLR 162

                  ....
gi 499201254  165 KMFA 168
Cdd:pfam04632 163 ARLR 166
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
25-146 4.12e-07

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 48.39  E-value: 4.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499201254   25 LTTAICMAFNLS-PTFAVISAIVTTEPTAADSLKKGLIRLPAAALGAFFAVLSAYFFGQTPITYAIV--SMITIAVCARL 101
Cdd:pfam13515   1 LAALIAELLGLPrGYWAPIAAAIVLQPTLGATLRRAVQRILGTVLGVLLGLLLLALLPGPLQLILVValLGFLAEYLIGR 80
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 499201254  102 RLDAGTLVATLTAVAMIP-STTDHLFADYVSRVAGTSLGIMISTFV 146
Cdd:pfam13515  81 NYALAQVFVTPLALLLASlAGGGGPPELALLRILDTLIGALIALLV 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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