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Conserved domains on  [gi|499212499|ref|WP_010910039|]
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sarcosine oxidase subunit beta [Mesorhizobium japonicum]

Protein Classification

sarcosine oxidase subunit beta( domain architecture ID 11492372)

sarcosine oxidase subunit beta is a part of a heterotetrameric sarcosine oxidase, which catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10-methylenetetrahydrofolate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
soxB TIGR01373
sarcosine oxidase, beta subunit family, heterotetrameric form; This model describes the beta ...
 3-409 0e+00

sarcosine oxidase, beta subunit family, heterotetrameric form; This model describes the beta subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms. [Energy metabolism, Amino acids and amines]


:

Pssm-ID: 273585 [Multi-domain]  Cd Length: 407  Bit Score: 777.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499    3 EYSAFSLLANALKGNRDWKPAWRKPDPKASYDVIIIGGGGHGLATAYYLAKEHGITNVAVLEKGWLGSGNVGRNTTAVRS 82
Cdd:TIGR01373   1 RYSAFSLLKEGLRGHRGWKPAWRSPEPKPTYDVIIVGGGGHGLATAYYLAKEHGITNVAVLEKGWLGGGNTGRNTTIVRS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499   83 NYLLPANTRFYEHSMKMWEGLSHELNYNVMFSQRGCLNLAHTPAQFDDYARRGNAMRHLGVDAELMTPAQIKRLIPAIDI 162
Cdd:TIGR01373  81 NYLYPESAELYEHAMKLWEGLSQDLNYNVMFSQRGVLNLCHSTADMDDGARRVNAMRLNGVDAELLSPEQVRRVIPILDF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  163 SGDARFPVVGGLMQRRAGTARHDAVAWGYARGADRRGVDIIENCEVTGF-LRDGDRITGVTTSRGDIRAKKVAVAVAGST 241
Cdd:TIGR01373 161 SPDARFPVVGGLLQRRGGTARHDAVAWGYARGADRRGVDIIQNCEVTGFiRRDGGRVIGVETTRGFIGAKKVGVAVAGHS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  242 GRVMQLAGIEtMPIESHVLQAFVTESLKPFIDTVVTFGMGHFYMSQSDKGGLVYGGDIDGYNSYAQRGNLPIVDEVMSEM 321
Cdd:TIGR01373 241 SVVAAMAGFR-LPIESHPLQALVSEPLKPIIDTVVMSNAVHFYVSQSDKGELVIGGGIDGYNSYAQRGNLPTLEHVLAAI 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  322 LALFPGLARVRMLRSWGGVCDMSMDGSPIITTGPLPGMYLNCGWCYGGFKATPASGWTFAWTIAKDEPHDFNAPFTLDRF 401
Cdd:TIGR01373 320 LEMFPILSRVRMLRSWGGIVDVTPDGSPIIGKTPLPNLYLNCGWGTGGFKATPASGTVFAHTLARGEPHDINAPFTLDRF 399


                  ....*...
gi 499212499  402 HRGLVIDD 409
Cdd:TIGR01373 400 HSGRLIDE 407
 
Name Accession Description Interval E-value
soxB TIGR01373
sarcosine oxidase, beta subunit family, heterotetrameric form; This model describes the beta ...
 3-409 0e+00

sarcosine oxidase, beta subunit family, heterotetrameric form; This model describes the beta subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273585 [Multi-domain]  Cd Length: 407  Bit Score: 777.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499    3 EYSAFSLLANALKGNRDWKPAWRKPDPKASYDVIIIGGGGHGLATAYYLAKEHGITNVAVLEKGWLGSGNVGRNTTAVRS 82
Cdd:TIGR01373   1 RYSAFSLLKEGLRGHRGWKPAWRSPEPKPTYDVIIVGGGGHGLATAYYLAKEHGITNVAVLEKGWLGGGNTGRNTTIVRS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499   83 NYLLPANTRFYEHSMKMWEGLSHELNYNVMFSQRGCLNLAHTPAQFDDYARRGNAMRHLGVDAELMTPAQIKRLIPAIDI 162
Cdd:TIGR01373  81 NYLYPESAELYEHAMKLWEGLSQDLNYNVMFSQRGVLNLCHSTADMDDGARRVNAMRLNGVDAELLSPEQVRRVIPILDF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  163 SGDARFPVVGGLMQRRAGTARHDAVAWGYARGADRRGVDIIENCEVTGF-LRDGDRITGVTTSRGDIRAKKVAVAVAGST 241
Cdd:TIGR01373 161 SPDARFPVVGGLLQRRGGTARHDAVAWGYARGADRRGVDIIQNCEVTGFiRRDGGRVIGVETTRGFIGAKKVGVAVAGHS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  242 GRVMQLAGIEtMPIESHVLQAFVTESLKPFIDTVVTFGMGHFYMSQSDKGGLVYGGDIDGYNSYAQRGNLPIVDEVMSEM 321
Cdd:TIGR01373 241 SVVAAMAGFR-LPIESHPLQALVSEPLKPIIDTVVMSNAVHFYVSQSDKGELVIGGGIDGYNSYAQRGNLPTLEHVLAAI 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  322 LALFPGLARVRMLRSWGGVCDMSMDGSPIITTGPLPGMYLNCGWCYGGFKATPASGWTFAWTIAKDEPHDFNAPFTLDRF 401
Cdd:TIGR01373 320 LEMFPILSRVRMLRSWGGIVDVTPDGSPIIGKTPLPNLYLNCGWGTGGFKATPASGTVFAHTLARGEPHDINAPFTLDRF 399


                  ....*...
gi 499212499  402 HRGLVIDD 409
Cdd:TIGR01373 400 HSGRLIDE 407
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
45-400 2.32e-80

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 251.75  E-value: 2.32e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  45 LATAYYLAKeHGItNVAVLEKGWLGSGNVGRNTTAVRSNYLLPAN---TRFYEHSMKMWEGLSHELNYNVMFSQRGCLNL 121
Cdd:COG0665   15 LSTAYHLAR-RGL-DVTVLERGRPGSGASGRNAGQLRPGLAALADralVRLAREALDLWRELAAELGIDCDFRRTGVLYL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 122 AHTPAQFDDYARRGNAMRHLGVDAELMTPAQIKRLIPAIDISGdarfpVVGGLMQRRAGTARHDAVAWGYARGADRRGVD 201
Cdd:COG0665   93 ARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPD-----YAGGLYDPDDGHVDPAKLVRALARAARAAGVR 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 202 IIENCEVTGFLRDGDRITGVTTSRGDIRAKKVAVAVAGSTGRVMQLAGIEtMPIESHVLQAFVTESLKPFIDTVVTFGmG 281
Cdd:COG0665  168 IREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLR-LPLRPVRGYVLVTEPLPDLPLRPVLDD-T 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 282 HFYMSQSDKGGLVYGGDIDgYNSYAQRGNLPIVDEVMSEMLALFPGLARVRMLRSWGGVCDMSMDGSPII-TTGPLPGMY 360
Cdd:COG0665  246 GVYLRPTADGRLLVGGTAE-PAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGLPIIgRLPGAPGLY 324

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 499212499 361 LNCGWCYGGFKATPASGWTFAWTIAKDEPHDFNAPFTLDR 400
Cdd:COG0665  325 VATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 45-381 3.87e-53

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 180.29  E-value: 3.87e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499   45 LATAYYLAKEHGitNVAVLEKG-WLGSGNVGRNTTAVRSNYLLPANT---RFYEHSMKMWEGLSHELNYNVMFSQRGCLN 120
Cdd:pfam01266  12 LSTAYELARRGL--SVTLLERGdDPGSGASGRNAGLIHPGLRYLEPSelaRLALEALDLWEELEEELGIDCGFRRCGVLV 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  121 LAHTPAQfDDYARRGNAMRHLGVDAELMTPAQIKRLIPAIDisgdarfPVVGGLMQRRAGTARHDAVAWGYARGADRRGV 200
Cdd:pfam01266  90 LARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEPLLP-------GLRGGLFYPDGGHVDPARLLRALARAAEALGV 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  201 DIIENCEVTGFLRDGDrITGVTTSrGDIRAkkVAVAVAGSTGRV-MQLAGIETMPIEShvlQAFVTESLKPFIDTVVTFG 279
Cdd:pfam01266 162 RIIEGTEVTGIEEEGG-VWGVVTT-GEADA--VVNAAGAWADLLaLPGLRLPVRPVRG---QVLVLEPLPEALLILPVPI 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  280 M----GHFYMSQSDKGGLVYGGDIDGYNSYAQRGNLPIVDEVMSEMLALFPGLARVrmLRSWGGVCDMSmDGSPIITTGP 355
Cdd:pfam01266 235 TvdpgRGVYLRPRADGRLLLGGTDEEDGFDDPTPDPEEIEELLEAARRLFPALADI--ERAWAGLRPLP-DGLPIIGRPG 311

                         330       340
                  ....*....|....*....|....*.
gi 499212499  356 LPGMYLNCGWCYGGFKATPASGWTFA 381
Cdd:pfam01266 312 SPGLYLATGHGGHGLTLAPGIGKLLA 337
PRK00711 PRK00711
D-amino acid dehydrogenase;
113-381 1.77e-12

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 68.67  E-value: 1.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 113 FSQRGCLNLAHTPAQFDDYARRGNAMRHLGVDAELMTPAQIKRLIPAIdisGDARFPVVGGLmqrragtaR--HDAVA-- 188
Cdd:PRK00711 132 GRQGGTLQLFRTQQQLDAAAKDIAVLEEAGVPYELLDRDELAAVEPAL---AGVRHKLVGGL--------RlpNDETGdc 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 189 ----WGYARGADRRGVDIIENCEVTGFLRDGDRITGVTTSRGDIRAKKVAVAV-AGSTGRVMQLaGIE-----------T 252
Cdd:PRK00711 201 qlftQRLAAMAEQLGVKFRFNTPVDGLLVEGGRITGVQTGGGVITADAYVVALgSYSTALLKPL-GVDipvyplkgyslT 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 253 MPIeshvlqafVTESLKPFIdTVvtfgmghfyMSQSDK------------GGLVyggDIDGYN---SYAQRGNLpivdev 317
Cdd:PRK00711 280 VPI--------TDEDRAPVS-TV---------LDETYKiaitrfddrirvGGMA---EIVGFDlrlDPARRETL------ 332

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499212499 318 msEML--ALFPGLARVRMLRSWGGVCDMSMDGSPIITTGPLPGMYLNCGwcYGgfkatpASGWTFA 381
Cdd:PRK00711 333 --EMVvrDLFPGGGDLSQATFWTGLRPMTPDGTPIVGATRYKNLWLNTG--HG------TLGWTMA 388
 
Name Accession Description Interval E-value
soxB TIGR01373
sarcosine oxidase, beta subunit family, heterotetrameric form; This model describes the beta ...
 3-409 0e+00

sarcosine oxidase, beta subunit family, heterotetrameric form; This model describes the beta subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273585 [Multi-domain]  Cd Length: 407  Bit Score: 777.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499    3 EYSAFSLLANALKGNRDWKPAWRKPDPKASYDVIIIGGGGHGLATAYYLAKEHGITNVAVLEKGWLGSGNVGRNTTAVRS 82
Cdd:TIGR01373   1 RYSAFSLLKEGLRGHRGWKPAWRSPEPKPTYDVIIVGGGGHGLATAYYLAKEHGITNVAVLEKGWLGGGNTGRNTTIVRS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499   83 NYLLPANTRFYEHSMKMWEGLSHELNYNVMFSQRGCLNLAHTPAQFDDYARRGNAMRHLGVDAELMTPAQIKRLIPAIDI 162
Cdd:TIGR01373  81 NYLYPESAELYEHAMKLWEGLSQDLNYNVMFSQRGVLNLCHSTADMDDGARRVNAMRLNGVDAELLSPEQVRRVIPILDF 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  163 SGDARFPVVGGLMQRRAGTARHDAVAWGYARGADRRGVDIIENCEVTGF-LRDGDRITGVTTSRGDIRAKKVAVAVAGST 241
Cdd:TIGR01373 161 SPDARFPVVGGLLQRRGGTARHDAVAWGYARGADRRGVDIIQNCEVTGFiRRDGGRVIGVETTRGFIGAKKVGVAVAGHS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  242 GRVMQLAGIEtMPIESHVLQAFVTESLKPFIDTVVTFGMGHFYMSQSDKGGLVYGGDIDGYNSYAQRGNLPIVDEVMSEM 321
Cdd:TIGR01373 241 SVVAAMAGFR-LPIESHPLQALVSEPLKPIIDTVVMSNAVHFYVSQSDKGELVIGGGIDGYNSYAQRGNLPTLEHVLAAI 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  322 LALFPGLARVRMLRSWGGVCDMSMDGSPIITTGPLPGMYLNCGWCYGGFKATPASGWTFAWTIAKDEPHDFNAPFTLDRF 401
Cdd:TIGR01373 320 LEMFPILSRVRMLRSWGGIVDVTPDGSPIIGKTPLPNLYLNCGWGTGGFKATPASGTVFAHTLARGEPHDINAPFTLDRF 399


                  ....*...
gi 499212499  402 HRGLVIDD 409
Cdd:TIGR01373 400 HSGRLIDE 407
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
45-400 2.32e-80

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 251.75  E-value: 2.32e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  45 LATAYYLAKeHGItNVAVLEKGWLGSGNVGRNTTAVRSNYLLPAN---TRFYEHSMKMWEGLSHELNYNVMFSQRGCLNL 121
Cdd:COG0665   15 LSTAYHLAR-RGL-DVTVLERGRPGSGASGRNAGQLRPGLAALADralVRLAREALDLWRELAAELGIDCDFRRTGVLYL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 122 AHTPAQFDDYARRGNAMRHLGVDAELMTPAQIKRLIPAIDISGdarfpVVGGLMQRRAGTARHDAVAWGYARGADRRGVD 201
Cdd:COG0665   93 ARTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPD-----YAGGLYDPDDGHVDPAKLVRALARAARAAGVR 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 202 IIENCEVTGFLRDGDRITGVTTSRGDIRAKKVAVAVAGSTGRVMQLAGIEtMPIESHVLQAFVTESLKPFIDTVVTFGmG 281
Cdd:COG0665  168 IREGTPVTGLEREGGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLR-LPLRPVRGYVLVTEPLPDLPLRPVLDD-T 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 282 HFYMSQSDKGGLVYGGDIDgYNSYAQRGNLPIVDEVMSEMLALFPGLARVRMLRSWGGVCDMSMDGSPII-TTGPLPGMY 360
Cdd:COG0665  246 GVYLRPTADGRLLVGGTAE-PAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGLPIIgRLPGAPGLY 324

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 499212499 361 LNCGWCYGGFKATPASGWTFAWTIAKDEPHDFNAPFTLDR 400
Cdd:COG0665  325 VATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 45-381 3.87e-53

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 180.29  E-value: 3.87e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499   45 LATAYYLAKEHGitNVAVLEKG-WLGSGNVGRNTTAVRSNYLLPANT---RFYEHSMKMWEGLSHELNYNVMFSQRGCLN 120
Cdd:pfam01266  12 LSTAYELARRGL--SVTLLERGdDPGSGASGRNAGLIHPGLRYLEPSelaRLALEALDLWEELEEELGIDCGFRRCGVLV 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  121 LAHTPAQfDDYARRGNAMRHLGVDAELMTPAQIKRLIPAIDisgdarfPVVGGLMQRRAGTARHDAVAWGYARGADRRGV 200
Cdd:pfam01266  90 LARDEEE-EALEKLLAALRRLGVPAELLDAEELRELEPLLP-------GLRGGLFYPDGGHVDPARLLRALARAAEALGV 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  201 DIIENCEVTGFLRDGDrITGVTTSrGDIRAkkVAVAVAGSTGRV-MQLAGIETMPIEShvlQAFVTESLKPFIDTVVTFG 279
Cdd:pfam01266 162 RIIEGTEVTGIEEEGG-VWGVVTT-GEADA--VVNAAGAWADLLaLPGLRLPVRPVRG---QVLVLEPLPEALLILPVPI 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  280 M----GHFYMSQSDKGGLVYGGDIDGYNSYAQRGNLPIVDEVMSEMLALFPGLARVrmLRSWGGVCDMSmDGSPIITTGP 355
Cdd:pfam01266 235 TvdpgRGVYLRPRADGRLLLGGTDEEDGFDDPTPDPEEIEELLEAARRLFPALADI--ERAWAGLRPLP-DGLPIIGRPG 311

                         330       340
                  ....*....|....*....|....*.
gi 499212499  356 LPGMYLNCGWCYGGFKATPASGWTFA 381
Cdd:pfam01266 312 SPGLYLATGHGGHGLTLAPGIGKLLA 337
PRK00711 PRK00711
D-amino acid dehydrogenase;
113-381 1.77e-12

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 68.67  E-value: 1.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 113 FSQRGCLNLAHTPAQFDDYARRGNAMRHLGVDAELMTPAQIKRLIPAIdisGDARFPVVGGLmqrragtaR--HDAVA-- 188
Cdd:PRK00711 132 GRQGGTLQLFRTQQQLDAAAKDIAVLEEAGVPYELLDRDELAAVEPAL---AGVRHKLVGGL--------RlpNDETGdc 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 189 ----WGYARGADRRGVDIIENCEVTGFLRDGDRITGVTTSRGDIRAKKVAVAV-AGSTGRVMQLaGIE-----------T 252
Cdd:PRK00711 201 qlftQRLAAMAEQLGVKFRFNTPVDGLLVEGGRITGVQTGGGVITADAYVVALgSYSTALLKPL-GVDipvyplkgyslT 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 253 MPIeshvlqafVTESLKPFIdTVvtfgmghfyMSQSDK------------GGLVyggDIDGYN---SYAQRGNLpivdev 317
Cdd:PRK00711 280 VPI--------TDEDRAPVS-TV---------LDETYKiaitrfddrirvGGMA---EIVGFDlrlDPARRETL------ 332

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499212499 318 msEML--ALFPGLARVRMLRSWGGVCDMSMDGSPIITTGPLPGMYLNCGwcYGgfkatpASGWTFA 381
Cdd:PRK00711 333 --EMVvrDLFPGGGDLSQATFWTGLRPMTPDGTPIVGATRYKNLWLNTG--HG------TLGWTMA 388
solA PRK11259
N-methyl-L-tryptophan oxidase;
100-401 2.28e-12

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 67.94  E-value: 2.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 100 WEGLSHELNYNVmFSQRGCLNLAHTPAQFDDYARRgnAMRHLGVDAELMTPAQIKRLIPAIDISGDARfpvvgGLMQRRA 179
Cdd:PRK11259  72 WRELERESGEPL-FVRTGVLNLGPADSDFLANSIR--SARQHGLPHEVLDAAEIRRRFPQFRLPDGYI-----ALFEPDG 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 180 GTARHDAVAWGYARGADRRGVDIIENCEVTGFLRDGDRITgVTTSRGDIRAKKVAVAvAGSTgrVMQLAGIETMPI--ES 257
Cdd:PRK11259 144 GFLRPELAIKAHLRLAREAGAELLFNEPVTAIEADGDGVT-VTTADGTYEAKKLVVS-AGAW--VKDLLPPLELPLtpVR 219

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 258 HVL-------QAFVTESLKPFIdtvVTFGMG-HFYMSQSDKGGLV------YGGDIDGYNSYAQRGNLPIVDEVMSEMLA 323
Cdd:PRK11259 220 QVLawfqadgRYSEPNRFPAFI---WEVPDGdQYYGFPAENGPGLkigkhnGGQEITSPDERDRFVTVAEDGAELRPFLR 296

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 324 -LFPGLARVrmLRswGGVC--DMSMDGSPIITTGP-LPGMYLNCGwCYG-GFKATPASGWTFA-WTIAKDEPHDFnAPFT 397
Cdd:PRK11259 297 nYLPGVGPC--LR--GAACtyTNTPDEHFIIDTLPgHPNVLVASG-CSGhGFKFASVLGEILAdLAQDGTSDFDL-SPFS 370


                 ....
gi 499212499 398 LDRF 401
Cdd:PRK11259 371 LSRF 374
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
32-251 4.02e-09

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 58.23  E-value: 4.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  32 SYDVIIigggghgLATAYYLAKEHGItNVAVLEKGW-LGSGNVGRN-----------------TTAVRSNyllpantrfy 93
Cdd:COG0579    4 MYDVVIigagivgLALARELSRYEDL-KVLVLEKEDdVAQESSGNNsgvihaglyytpgslkaRLCVEGN---------- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  94 ehsmKMWEGLSHELnyNVMFSQRGCLNLAHTPAQFDDYARRGNAMRHLGV-DAELMTPAQIKRLIPAIDISGDA--RFP- 169
Cdd:COG0579   73 ----ELFYELCREL--GIPFKRCGKLVVATGEEEVAFLEKLYERGKANGVpGLEILDREELRELEPLLSDEGVAalYSPs 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 170 --VV--GGLMQRragtarhdavawgYARGADRRGVDIIENCEVTGFLRDGDRITgVTTSRGDIRAKKVAVAVAGSTGRVM 245
Cdd:COG0579  147 tgIVdpGALTRA-------------LAENAEANGVELLLNTEVTGIEREGDGWE-VTTNGGTIRARFVINAAGLYADRLA 212


                 ....*.
gi 499212499 246 QLAGIE 251
Cdd:COG0579  213 QMAGIG 218
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 46-401 1.28e-06

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 50.21  E-value: 1.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499   46 ATAYYLAKeHGItNVAVLEKGWL--GSGNVGRNTTAVRSNYLLPANTRFYEHSMKMWEGLSHELNYNVmfsqrgclnlaH 123
Cdd:TIGR01377  14 FAAYHLAK-HGK-KTLLLEQFDLphSRGSSHGQSRIIRKAYPEDFYTPMMLECYQLWAQLEKEAGTKL-----------H 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  124 TPAQFDDYARRGNAM---------RHlGVDAELMTPAQIKRLIPAIDISGDARfpvvgGLMQRRAGTARHDAVAWGYARG 194
Cdd:TIGR01377  81 RQTGLLLLGPKENQFlktiqatlsRH-GLEHELLSSKQLKQRFPNIRVPRNEV-----GLLDPNGGVLYAEKALRALQEL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  195 ADRRGVDIIENCEVTGFLRDGDRITgVTTSRGDIRAKKVAVAVAGSTGRVMQLAGIEtMPIE------------------ 256
Cdd:TIGR01377 155 AEAHGATVRDGTKVVEIEPTELLVT-VKTTKGSYQANKLVVTAGAWTSKLLSPLGIE-IPLQplrinvcywrekepgsyg 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499  257 -SHVLQAFVTESLKPFIdtvvtFGMGHFYMSQSDKGGLVYGGDIDGYNSYAQRGNLPIVDEVMSEMLA-LFPGLarvRML 334
Cdd:TIGR01377 233 vSQAFPCFLVLGLNPHI-----YGLPSFEYPGLMKVYYHHGQQIDPDERDCPFGADIEDVQILRKFVRdHLPGL---NGE 304

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499212499  335 RSWGGVCDMSM--DGSPIITTGP-LPGMYLNCGWCYGGFKATPASGWTFAWTIAKDEP-HDFnAPFTLDRF 401
Cdd:TIGR01377 305 PKKGEVCMYTNtpDEHFVIDLHPkYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPsYDL-AIFSLNRF 374
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
142-252 5.19e-06

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 48.28  E-value: 5.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 142 GVDAELMTPAQIKRLIPaiDISGdarfpvVGGLMQRRAGTARHDAVAWGYARGADRRGVDIIENCEVTGFLRDGDRITgV 221
Cdd:PRK11728 114 GIEVERLDAEELREREP--NIRG------LGAIFVPSTGIVDYRAVAEAMAELIQARGGEIRLGAEVTALDEHANGVV-V 184

                         90       100       110
                 ....*....|....*....|....*....|..
gi 499212499 222 TTSRGDIRAKKVaVAVAG-STGRVMQLAGIET 252
Cdd:PRK11728 185 RTTQGEYEARTL-INCAGlMSDRLAKMAGLEP 215
glpA PRK11101
anaerobic glycerol-3-phosphate dehydrogenase subunit A;
142-340 1.40e-05

anaerobic glycerol-3-phosphate dehydrogenase subunit A;


Pssm-ID: 236847 [Multi-domain]  Cd Length: 546  Bit Score: 47.32  E-value: 1.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 142 GVDAELMTPAQIKRLIPAIDisgdarfPVVGGLMQRRAGTARHDAVAWGYARGADRRGVDIIENCEVTGFLRDGDRITGV 221
Cdd:PRK11101 113 GIEAEAIDPQQALILEPAVN-------PALIGAVKVPDGTVDPFRLTAANMLDAKEHGAQILTYHEVTGLIREGDTVCGV 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 222 ------TTSRGDIRAKKVaVAVAGSTG-RVMQLA--GIETMP-----------IESHVLQafvtESLKPfidtvvtfgmg 281
Cdd:PRK11101 186 rvrdhlTGETQEIHAPVV-VNAAGIWGqHIAEYAdlRIRMFPakgsllimdhrINNHVIN----RCRKP----------- 249

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499212499 282 hfymsqSDKGGLVYGGDID--GYNS----YAQRGNLPI----VDEVMSEMLALFPGLARVRMLRSWGGV 340
Cdd:PRK11101 250 ------ADADILVPGDTISliGTTStridYDQIDDNRVtaeeVDILLREGEKLAPVMAKTRILRAYAGV 312
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 156-237 3.38e-05

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 46.00  E-value: 3.38e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 156 LIPAIDISGDARFPVvGGlMQrragtarhdAVAWGYARGADRRGVDIIENCEVTGFLRDGDRITGVTTSRGD-IRAKKVA 234
Cdd:COG1233  204 LIAYLEYAGGVWYPK-GG-MG---------ALADALARLAEELGGEIRTGAEVERILVEGGRATGVRLADGEeIRADAVV 272


                 ...
gi 499212499 235 VAV 237
Cdd:COG1233  273 SNA 275
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
136-292 6.88e-05

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 44.19  E-value: 6.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 136 NAMRHLGVDAELMTPAQIKRLIPAIDISGDARFPVVGGLMQRRAGTARHdavawgYARGADRRGVDIIENCEVTGFLRDG 215
Cdd:COG0644   43 EELEPLGLDEPLERPVRGARFYSPGGKSVELPPGRGGGYVVDRARFDRW------LAEQAEEAGAEVRTGTRVTDVLRDD 116

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499212499 216 DRITgVTTSRGD-IRAKKVAVAvAGSTGRVMQLAGIETMPIE-SHVLQAFVTESLKPFIDTVVTFGMGHFYMSQSDKGG 292
Cdd:COG0644  117 GRVV-VRTGDGEeIRADYVVDA-DGARSLLARKLGLKRRSDEpQDYALAIKEHWELPPLEGVDPGAVEFFFGEGAPGGY 193
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 165-247 4.43e-04

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 42.13  E-value: 4.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499212499 165 DARFPVVGGLMQRRAGTARHD---AVAWGYARGADRRGVDIIENCEVTGFLRDGDRITGVTTSRGD-----IRAKKVAVA 236
Cdd:COG1053  111 DGRLPQFGGHSVGRTCYAGDGtghALLATLYQAALRLGVEIFTETEVLDLIVDDGRVVGVVARDRTgeivrIRAKAVVLA 190

                         90
                 ....*....|.
gi 499212499 237 vAGSTGRVMQL 247
Cdd:COG1053  191 -TGGFGRNYEM 200
PRK08274 PRK08274
FAD-dependent tricarballylate dehydrogenase TcuA;
191-239 9.52e-04

FAD-dependent tricarballylate dehydrogenase TcuA;


Pssm-ID: 236214 [Multi-domain]  Cd Length: 466  Bit Score: 41.40  E-value: 9.52e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 499212499 191 YARGADRRGVDIIENCEVTGFLRDGDRITGVTTSRGD-----IRAKKVAVAVAG 239
Cdd:PRK08274 137 LYRSAERLGVEIRYDAPVTALELDDGRFVGARAGSAAggaerIRAKAVVLAAGG 190
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
195-252 2.42e-03

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 39.96  E-value: 2.42e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 499212499 195 ADRRGVDIIENCEVTGFLRDGDRITgVTTSRGDIRAKKVAVAVAGSTGRVMQLAGIET 252
Cdd:PRK07333 121 AEALGIDLREATSVTDFETRDEGVT-VTLSDGSVLEARLLVAADGARSKLRELAGIKT 177
PRK06185 PRK06185
FAD-dependent oxidoreductase;
202-252 3.17e-03

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 39.46  E-value: 3.17e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 499212499 202 IIENCEVTGFLRDGDRITGVTTSRGD----IRAKKVaVAVAGSTGRVMQLAGIET 252
Cdd:PRK06185 126 LRMGAEVTGLIEEGGRVTGVRARTPDgpgeIRADLV-VGADGRHSRVRALAGLEV 179
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
191-236 5.05e-03

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 38.74  E-value: 5.05e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 499212499  191 YARGADRRGVDIIENCEVTGFLRDGDRITgVTTSRGDIRAKKVAVA 236
Cdd:pfam13738  81 LRRVADHFELPINLFEEVTSVKKEDDGFV-VTTSKGTYQARYVIIA 125
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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