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NADP-dependent malic enzyme [Caulobacter vibrioides]
Protein Classification
NADP-dependent malic enzyme ( domain architecture ID 11482649 )
NADP-dependent malic enzyme catalyzes the conversion of (S)-malate to pyruvate and carbon dioxide using NADP as a cofactor
List of domain hits
Name
Accession
Description
Interval
E-value
PRK07232
PRK07232 bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
14-758
0e+00
bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
Pssm-ID: 235976 [Multi-domain]
Cd Length: 752
Bit Score: 1293.13
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 14 FTDAE AL AF HR Y P T PGKI AIV PTKP M ATQRDLSLAYSPGVA V P VHA IA A DP DM AY E YT SK GNLVAVISNGTA I LGLG DL G 93
Cdd:PRK07232 2 QLKQA AL DY HR F P R PGKI EVT PTKP L ATQRDLSLAYSPGVA A P CLE IA K DP AD AY K YT AR GNLVAVISNGTA V LGLG NI G 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 94 ALASKPVMEGK S VLFK R F GDV D SI DIEV TTK DPD EI I TV V KNIGV TFGGINLEDIK S PECF R IE TE L Q E LL DIPVFHDDQ 173
Cdd:PRK07232 82 ALASKPVMEGK G VLFK K F AGI D VF DIEV DEE DPD KF I EA V AALEP TFGGINLEDIK A PECF Y IE EK L R E RM DIPVFHDDQ 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 174 HGTAII C AA G L I NA CHIT GKKIEDVK V V LN G P GAA G IA S L E L IK A M G VRA EN C I AV DSKGV L Y R GRTEGM NQ WK S A H AV E 253
Cdd:PRK07232 162 HGTAII S AA A L L NA LELV GKKIEDVK I V VS G A GAA A IA C L N L LV A L G AKK EN I I VC DSKGV I Y K GRTEGM DE WK A A Y AV D 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 254 TD K RTLAEA VV GADV L LGLSA K G AF TPEM IA SMA P NP V IFA M ANPDPEITPEE V K R VR K DAI MG TGRSDYPNQVNNVL G F 333
Cdd:PRK07232 242 TD A RTLAEA IE GADV F LGLSA A G VL TPEM VK SMA D NP I IFA L ANPDPEITPEE A K A VR P DAI IA TGRSDYPNQVNNVL C F 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 334 PYIFRGALDV R A RRV N H EMK I A CAQ A L A M LARE D V P DEVAAAY H G RQ L K FGP D YIIP SA FDPRLI WYVP P F VA Q AAMD T G 413
Cdd:PRK07232 322 PYIFRGALDV G A TTI N E EMK L A AVR A I A E LARE E V S DEVAAAY G G QK L S FGP E YIIP KP FDPRLI VKIA P A VA K AAMD S G 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 414 VA RK PIADMDAYR AG L AQRLDP T AGFLQK I SGSVLAN PKR I VFAEGE DPS V I RAA YAYQSG G FG K A IL C GR ENLVHENM K 493
Cdd:PRK07232 402 VA TR PIADMDAYR EK L EAFVYK T GLVMKP I FAKAKKD PKR V VFAEGE EER V L RAA QEVVDE G LA K P IL I GR PEVIEARI K 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 494 LV GLD - PDTAGL EI I N ARLSD R NPD Y VDAL Y AR LQR Q G YLKR D VQ RL INQ DR NSFA A S MV TL G E AD G M VT G V T RSFDQA L 572
Cdd:PRK07232 482 KL GLD l KAGVDF EI V N PEDDP R YEE Y WQYY Y EL LQR K G VTPE D AR RL VRR DR TVIG A M MV AR G D AD A M IC G L T GRYHEH L 561
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 573 EE V LR V VDPA PG - GRIMG M SVV L A KG RTI F V ADT N V T E L P E AEEL V EIA CE AA RA VRR L G FK PRVA FM S Y S T FG NPMGLR 651
Cdd:PRK07232 562 RP V RQ V IGLR PG v HTAAA M NAL L L KG GNL F I ADT Y V N E D P T AEEL A EIA LM AA EE VRR F G IE PRVA LL S H S N FG SSDSPS 641
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 652 SE K V REAV AM L D E MEV D F E YE GEM PPEL AL DP E K R A - N YPF M RL TDS AN I L I MP AIH AA S IS TK L VQS LGG ATV IGP V LL 730
Cdd:PRK07232 642 AR K M REAV EL L R E RAP D L E VD GEM HGDA AL NE E I R K d L YPF S RL KGP AN V L V MP NLE AA N IS YN L LKE LGG GVT IGP I LL 721
730 740
....*....|....*....|....*...
gi 499223838 731 G LS K S V Q I APL SA S V SK I L NM AMM A AY D 758
Cdd:PRK07232 722 G MA K P V H I LTP SA T V RR I V NM TAL A VV D 749
Name
Accession
Description
Interval
E-value
PRK07232
PRK07232 bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
14-758
0e+00
bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
Pssm-ID: 235976 [Multi-domain]
Cd Length: 752
Bit Score: 1293.13
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 14 FTDAE AL AF HR Y P T PGKI AIV PTKP M ATQRDLSLAYSPGVA V P VHA IA A DP DM AY E YT SK GNLVAVISNGTA I LGLG DL G 93
Cdd:PRK07232 2 QLKQA AL DY HR F P R PGKI EVT PTKP L ATQRDLSLAYSPGVA A P CLE IA K DP AD AY K YT AR GNLVAVISNGTA V LGLG NI G 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 94 ALASKPVMEGK S VLFK R F GDV D SI DIEV TTK DPD EI I TV V KNIGV TFGGINLEDIK S PECF R IE TE L Q E LL DIPVFHDDQ 173
Cdd:PRK07232 82 ALASKPVMEGK G VLFK K F AGI D VF DIEV DEE DPD KF I EA V AALEP TFGGINLEDIK A PECF Y IE EK L R E RM DIPVFHDDQ 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 174 HGTAII C AA G L I NA CHIT GKKIEDVK V V LN G P GAA G IA S L E L IK A M G VRA EN C I AV DSKGV L Y R GRTEGM NQ WK S A H AV E 253
Cdd:PRK07232 162 HGTAII S AA A L L NA LELV GKKIEDVK I V VS G A GAA A IA C L N L LV A L G AKK EN I I VC DSKGV I Y K GRTEGM DE WK A A Y AV D 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 254 TD K RTLAEA VV GADV L LGLSA K G AF TPEM IA SMA P NP V IFA M ANPDPEITPEE V K R VR K DAI MG TGRSDYPNQVNNVL G F 333
Cdd:PRK07232 242 TD A RTLAEA IE GADV F LGLSA A G VL TPEM VK SMA D NP I IFA L ANPDPEITPEE A K A VR P DAI IA TGRSDYPNQVNNVL C F 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 334 PYIFRGALDV R A RRV N H EMK I A CAQ A L A M LARE D V P DEVAAAY H G RQ L K FGP D YIIP SA FDPRLI WYVP P F VA Q AAMD T G 413
Cdd:PRK07232 322 PYIFRGALDV G A TTI N E EMK L A AVR A I A E LARE E V S DEVAAAY G G QK L S FGP E YIIP KP FDPRLI VKIA P A VA K AAMD S G 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 414 VA RK PIADMDAYR AG L AQRLDP T AGFLQK I SGSVLAN PKR I VFAEGE DPS V I RAA YAYQSG G FG K A IL C GR ENLVHENM K 493
Cdd:PRK07232 402 VA TR PIADMDAYR EK L EAFVYK T GLVMKP I FAKAKKD PKR V VFAEGE EER V L RAA QEVVDE G LA K P IL I GR PEVIEARI K 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 494 LV GLD - PDTAGL EI I N ARLSD R NPD Y VDAL Y AR LQR Q G YLKR D VQ RL INQ DR NSFA A S MV TL G E AD G M VT G V T RSFDQA L 572
Cdd:PRK07232 482 KL GLD l KAGVDF EI V N PEDDP R YEE Y WQYY Y EL LQR K G VTPE D AR RL VRR DR TVIG A M MV AR G D AD A M IC G L T GRYHEH L 561
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 573 EE V LR V VDPA PG - GRIMG M SVV L A KG RTI F V ADT N V T E L P E AEEL V EIA CE AA RA VRR L G FK PRVA FM S Y S T FG NPMGLR 651
Cdd:PRK07232 562 RP V RQ V IGLR PG v HTAAA M NAL L L KG GNL F I ADT Y V N E D P T AEEL A EIA LM AA EE VRR F G IE PRVA LL S H S N FG SSDSPS 641
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 652 SE K V REAV AM L D E MEV D F E YE GEM PPEL AL DP E K R A - N YPF M RL TDS AN I L I MP AIH AA S IS TK L VQS LGG ATV IGP V LL 730
Cdd:PRK07232 642 AR K M REAV EL L R E RAP D L E VD GEM HGDA AL NE E I R K d L YPF S RL KGP AN V L V MP NLE AA N IS YN L LKE LGG GVT IGP I LL 721
730 740
....*....|....*....|....*...
gi 499223838 731 G LS K S V Q I APL SA S V SK I L NM AMM A AY D 758
Cdd:PRK07232 722 G MA K P V H I LTP SA T V RR I V NM TAL A VV D 749
SfcA
COG0281 Malic enzyme [Energy production and conversion]; Malic enzyme is part of the Pathway/BioSystem: ...
7-433
0e+00
Malic enzyme [Energy production and conversion]; Malic enzyme is part of the Pathway/BioSystem: Urea cycle
Pssm-ID: 440050 [Multi-domain]
Cd Length: 414
Bit Score: 699.46
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 7 S D A ER KTFTDA EAL AF HR YPTP GKI AIV PT K P MA TQ R DLSLAY S PGVA VPVHA IA A DP DM AY E YT S KGNLVAV ISN GTA I 86
Cdd:COG0281 1 E D M ER VETLEQ EAL EY HR IYDR GKI LVY PT V P LH TQ E DLSLAY T PGVA EACLE IA E DP RL AY G YT A KGNLVAV VTD GTA V 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 87 LGLGD L G A LA SK PVMEGK S VLFK R F GDV D SID I EVT T K DPDE IITV VK NIGV TFGGINLEDIK S P E CF R IE TE L Q E L LDI 166
Cdd:COG0281 81 LGLGD I G P LA GM PVMEGK A VLFK A F AGI D AFP I CLD T N DPDE FVEA VK ALEP TFGGINLEDIK A P N CF E IE ER L R E E LDI 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 167 PVFHDDQHGTAI ICA A G L I NA CHIT GKK I ED V K V V L NG P GAAGIA SLE L IK A M G VRA EN C I A VDSKG V LY R GRT e GM N QW 246
Cdd:COG0281 161 PVFHDDQHGTAI VVL A A L L NA LKLV GKK L ED Q K I V I NG A GAAGIA IAR L LV A A G LSE EN I I M VDSKG L LY E GRT - DL N PY 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 247 K SAH A VE T DK R ---- TLAEA VV GADV LL G L SA K GAFT P EM IA SMA PN P V IFA M ANP D PEITPE EV K RVRKD AI MG TGRSD 322
Cdd:COG0281 240 K REF A RD T NP R glkg TLAEA IK GADV FI G V SA P GAFT E EM VK SMA KR P I IFA L ANP T PEITPE DA K AWGDG AI VA TGRSD 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 323 YPNQVNNVL G FP Y IFRGALDVRA R R VNH EMK I A C A Q ALA M L AR E D vpdevaaayhgrql KF GPDYIIPS A FDPR LIWY V P 402
Cdd:COG0281 320 YPNQVNNVL I FP G IFRGALDVRA T R ITD EMK L A A A R ALA D L VD E E -------------- EL GPDYIIPS P FDPR VSPA V A 385
410 420 430
....*....|....*....|....*....|.
gi 499223838 403 PF VA Q AA MDT GVAR K PI A dm DA YR AG L AQ R L 433
Cdd:COG0281 386 AA VA K AA IES GVAR R PI D -- ED YR EA L EA R M 414
Malic_M
smart00919 Malic enzyme, NAD binding domain; Malic enzymes (malate oxidoreductases) catalyse the ...
173-410
2.41e-116
Malic enzyme, NAD binding domain; Malic enzymes (malate oxidoreductases) catalyse the oxidative decarboxylation of malate to form pyruvate.
Pssm-ID: 214912
Cd Length: 231
Bit Score: 350.56
E-value: 2.41e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 173 Q H GTAI ICA AGL I NA CH ITGKK I ED VKV V L NG P GAAGI ASLE L IK A M GV RAE N CIA VDSKG V L YR GR TEGM N QW K SAH A V 252
Cdd:smart00919 1 Q Q GTAI VVL AGL L NA LK ITGKK L ED QRI V V NG A GAAGI GIAK L LV A A GV KRK N IWL VDSKG L L TK GR EDNL N PY K KPF A R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 253 E T DK R --- TL A EAV V GADVL L G L S AK - GAFT P EM IA SMA PN P V IFA MA NP D PEI T P EEVKRV R K - D AI MG TGRSDYPNQV 327
Cdd:smart00919 81 K T NE R etg TL E EAV K GADVL I G V S GP g GAFT E EM VK SMA ER P I IFA LS NP T PEI E P TAADAY R W t A AI VA TGRSDYPNQV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 328 NNVL G FP Y IF R GALDVRARR VNH EMK I A C A Q AL amlaredvpdev A A A YHGRQLKF GP D YIIPS A FD P R LIWY V PPF VA Q 407
Cdd:smart00919 161 NNVL I FP G IF L GALDVRARR ITD EMK L A A A E AL ------------ A D A VPVSEEEL GP G YIIPS P FD R R VSAR V AVA VA K 228
...
gi 499223838 408 AA M 410
Cdd:smart00919 229 AA I 231
NAD_bind_2_malic_enz
cd05311 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Malic enzyme (ME), a member of the ...
173-409
2.33e-101
NAD(P) binding domain of malic enzyme (ME), subgroup 2; Malic enzyme (ME), a member of the amino acid dehydrogenase (DH)-like domain family, catalyzes the oxidative decarboxylation of L-malate to pyruvate in the presence of cations (typically Mg++ or Mn++) with the concomitant reduction of cofactor NAD+ or NADP+. ME has been found in all organisms, and plays important roles in diverse metabolic pathways such as photosynthesis and lipogenesis. This enzyme generally forms homotetramers. The conversion of malate to pyruvate by ME typically involves oxidation of malate to produce oxaloacetate, followed by decarboxylation of oxaloacetate to produce pyruvate and CO2. This subfamily consists primarily of archaeal and bacterial ME. Amino acid DH-like NAD(P)-binding domains are members of the Rossmann fold superfamily and include glutamate, leucine, and phenylalanine DHs, methylene tetrahydrofolate DH, methylene-tetrahydromethanopterin DH, methylene-tetrahydropholate DH/cyclohydrolase, Shikimate DH-like proteins, malate oxidoreductases, and glutamyl tRNA reductase. Amino acid DHs catalyze the deamination of amino acids to keto acids with NAD(P)+ as a cofactor. The NAD(P)-binding Rossmann fold superfamily includes a wide variety of protein families including NAD(P)- binding domains of alcohol DHs, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate DH, lactate/malate DHs, formate/glycerate DHs, siroheme synthases, 6-phosphogluconate DH, amino acid DHs, repressor rex, NAD-binding potassium channel domain, CoA-binding, and ornithine cyclodeaminase-like domains. These domains have an alpha-beta-alpha configuration. NAD binding involves numerous hydrogen and van der Waals contacts.
Pssm-ID: 133453 [Multi-domain]
Cd Length: 226
Bit Score: 311.51
E-value: 2.33e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 173 QHGTAI ICA AGL I NA CHIT GKKIE D VK V V L NG P GAAGIA SLE L IK A M G VRA EN CIA VDSKGV L Y R GR TEGM N QW K SAH A V 252
Cdd:cd05311 1 QHGTAI VTL AGL L NA LKLV GKKIE E VK I V I NG A GAAGIA IAR L LL A A G AKP EN IVV VDSKGV I Y E GR EDDL N PD K NEI A K 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 253 ET DKR ---- TL A EA VV GADV LL G L S AK G AFTP EMI AS MA PN P VI FA M ANP D PEI T PEE V K RVRK D a I MG TGRSD Y PNQVN 328
Cdd:cd05311 81 ET NPE ktgg TL K EA LK GADV FI G V S RP G VVKK EMI KK MA KD P IV FA L ANP V PEI W PEE A K EAGA D - I VA TGRSD F PNQVN 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 329 NVLGFP Y IFRGALDVRA RRVNH EMK I A C A Q A L A M LA R E D V P devaaayhgrqlkf G PD YIIP SA FDPR LIWY V PPF VA Q A 408
Cdd:cd05311 160 NVLGFP G IFRGALDVRA TKITE EMK L A A A E A I A D LA E E E V L -------------- G EE YIIP TP FDPR VVPR V ATA VA K A 225
.
gi 499223838 409 A 409
Cdd:cd05311 226 A 226
PTA_PTB
pfam01515 Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase ...
439-756
2.57e-90
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyze the transfer of an acetyl or butaryl group to orthophosphate.
Pssm-ID: 396207 [Multi-domain]
Cd Length: 318
Bit Score: 286.13
E-value: 2.57e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 439 FL QK I SGSVLANP KRIVF A EGED PS V IR AA YAYQSG G FGKA IL C G R E N lv HENM K LV GLD P D TA G L EI INARL S D R NPD Y 518
Cdd:pfam01515 1 FL ER I FERAKKAK KRIVF P EGED ER V LK AA QKLLQQ G IADP IL I G D E I -- EIKA K AL GLD L D LD G I EI VDPET S P R LEE Y 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 519 V D AL Y ARLQ R Q G YLKRDVQR l I NQ D R N S FAA SM V T LGEADGMV T G VTRSFDQA L EEV L RVVDPA PG GRIM - GMSVV L AKG 597
Cdd:pfam01515 79 A D FY Y ELRK R K G MTPEIARE - I VR D P N Y FAA ML V K LGEADGMV S G AVNTTADT L RPA L QIIGTK PG VKTV s SVFIM L LPD 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 598 RTI F V AD TN V TEL P E AEEL V EIA CEA A RAVR R L G F - K PRVA FM SYSTFG NPM G LRS EKVREA VAMLD E MEV D FEYE GE MP 676
Cdd:pfam01515 158 GLL F F AD CA V NPN P T AEEL A EIA LMS A KTAK R F G I i E PRVA LL SYSTFG SGK G EDV EKVREA TKIVR E RAP D LVVD GE LQ 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 677 PEL AL DP E KR A N - Y P FMRLTDS AN ILIM P AIH A AS I ST K LV Q S LGGA TV IGP V L L GL S K S V QIAPLS ASV SK I L N M A MMA 755
Cdd:pfam01515 238 FDA AL VE E VA A Q k A P DSPVAGK AN VFVF P DLE A GN I GY K IA Q R LGGA EA IGP I L Q GL A K P V NDLSRG ASV ED I V N T A AIT 317
.
gi 499223838 756 A 756
Cdd:pfam01515 318 A 318
Name
Accession
Description
Interval
E-value
PRK07232
PRK07232 bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
14-758
0e+00
bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed
Pssm-ID: 235976 [Multi-domain]
Cd Length: 752
Bit Score: 1293.13
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 14 FTDAE AL AF HR Y P T PGKI AIV PTKP M ATQRDLSLAYSPGVA V P VHA IA A DP DM AY E YT SK GNLVAVISNGTA I LGLG DL G 93
Cdd:PRK07232 2 QLKQA AL DY HR F P R PGKI EVT PTKP L ATQRDLSLAYSPGVA A P CLE IA K DP AD AY K YT AR GNLVAVISNGTA V LGLG NI G 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 94 ALASKPVMEGK S VLFK R F GDV D SI DIEV TTK DPD EI I TV V KNIGV TFGGINLEDIK S PECF R IE TE L Q E LL DIPVFHDDQ 173
Cdd:PRK07232 82 ALASKPVMEGK G VLFK K F AGI D VF DIEV DEE DPD KF I EA V AALEP TFGGINLEDIK A PECF Y IE EK L R E RM DIPVFHDDQ 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 174 HGTAII C AA G L I NA CHIT GKKIEDVK V V LN G P GAA G IA S L E L IK A M G VRA EN C I AV DSKGV L Y R GRTEGM NQ WK S A H AV E 253
Cdd:PRK07232 162 HGTAII S AA A L L NA LELV GKKIEDVK I V VS G A GAA A IA C L N L LV A L G AKK EN I I VC DSKGV I Y K GRTEGM DE WK A A Y AV D 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 254 TD K RTLAEA VV GADV L LGLSA K G AF TPEM IA SMA P NP V IFA M ANPDPEITPEE V K R VR K DAI MG TGRSDYPNQVNNVL G F 333
Cdd:PRK07232 242 TD A RTLAEA IE GADV F LGLSA A G VL TPEM VK SMA D NP I IFA L ANPDPEITPEE A K A VR P DAI IA TGRSDYPNQVNNVL C F 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 334 PYIFRGALDV R A RRV N H EMK I A CAQ A L A M LARE D V P DEVAAAY H G RQ L K FGP D YIIP SA FDPRLI WYVP P F VA Q AAMD T G 413
Cdd:PRK07232 322 PYIFRGALDV G A TTI N E EMK L A AVR A I A E LARE E V S DEVAAAY G G QK L S FGP E YIIP KP FDPRLI VKIA P A VA K AAMD S G 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 414 VA RK PIADMDAYR AG L AQRLDP T AGFLQK I SGSVLAN PKR I VFAEGE DPS V I RAA YAYQSG G FG K A IL C GR ENLVHENM K 493
Cdd:PRK07232 402 VA TR PIADMDAYR EK L EAFVYK T GLVMKP I FAKAKKD PKR V VFAEGE EER V L RAA QEVVDE G LA K P IL I GR PEVIEARI K 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 494 LV GLD - PDTAGL EI I N ARLSD R NPD Y VDAL Y AR LQR Q G YLKR D VQ RL INQ DR NSFA A S MV TL G E AD G M VT G V T RSFDQA L 572
Cdd:PRK07232 482 KL GLD l KAGVDF EI V N PEDDP R YEE Y WQYY Y EL LQR K G VTPE D AR RL VRR DR TVIG A M MV AR G D AD A M IC G L T GRYHEH L 561
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 573 EE V LR V VDPA PG - GRIMG M SVV L A KG RTI F V ADT N V T E L P E AEEL V EIA CE AA RA VRR L G FK PRVA FM S Y S T FG NPMGLR 651
Cdd:PRK07232 562 RP V RQ V IGLR PG v HTAAA M NAL L L KG GNL F I ADT Y V N E D P T AEEL A EIA LM AA EE VRR F G IE PRVA LL S H S N FG SSDSPS 641
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 652 SE K V REAV AM L D E MEV D F E YE GEM PPEL AL DP E K R A - N YPF M RL TDS AN I L I MP AIH AA S IS TK L VQS LGG ATV IGP V LL 730
Cdd:PRK07232 642 AR K M REAV EL L R E RAP D L E VD GEM HGDA AL NE E I R K d L YPF S RL KGP AN V L V MP NLE AA N IS YN L LKE LGG GVT IGP I LL 721
730 740
....*....|....*....|....*...
gi 499223838 731 G LS K S V Q I APL SA S V SK I L NM AMM A AY D 758
Cdd:PRK07232 722 G MA K P V H I LTP SA T V RR I V NM TAL A VV D 749
PRK12862
PRK12862 malic enzyme; Reviewed
5-762
0e+00
malic enzyme; Reviewed
Pssm-ID: 183799 [Multi-domain]
Cd Length: 763
Bit Score: 1245.16
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 5 DM SDA ER K TFTDAE AL AF HR Y PTPGKI A I V PTKP M A T QRDL S LAYSPGVA V P VHA IAADP DM A YE YTS K GNLVAV I SNGT 84
Cdd:PRK12862 1 TS SDA SA K AELREA AL DY HR F PTPGKI E I A PTKP L A N QRDL A LAYSPGVA A P CLE IAADP AN A AR YTS R GNLVAV V SNGT 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 85 A I LGLG DL G A LASKPVMEGK S VLFK R F GDV D SI DIE VTTK DPD EIITV V KNIGV TFGGINLEDIK S PECF R IE T EL Q E LL 164
Cdd:PRK12862 81 A V LGLG NI G P LASKPVMEGK A VLFK K F AGI D VF DIE LDES DPD KLVEI V AALEP TFGGINLEDIK A PECF Y IE R EL R E RM 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 165 D IPVFHDDQHGTAII C AA G L I N ACHIT GK K IEDVK V V LN G P GAA GI A S L E L IKAM GV RA EN CIAV D S KGV L Y R GRTE G M N 244
Cdd:PRK12862 161 K IPVFHDDQHGTAII V AA A L L N GLKLV GK D IEDVK L V AS G A GAA AL A C L D L LVSL GV KR EN IWVT D I KGV V Y E GRTE L M D 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 245 Q WK SAH A VE TD K RTLAE AVV GADV L LGLSA K G AFT PEM IAS MAP N P V IFA M ANP D PEI T PEE VKR VR K DAI MG TGRSDYP 324
Cdd:PRK12862 241 P WK ARY A QK TD A RTLAE VIE GADV F LGLSA A G VLK PEM VKK MAP R P L IFA L ANP T PEI L PEE ARA VR P DAI IA TGRSDYP 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 325 NQVNNVL G FPYIFRGALDV R A RRV N H EMKIA CAQ A L A M LARE DVP D E VAAAY H G RQ L K FGPDY I IP SA FDPRLI WYVP P F 404
Cdd:PRK12862 321 NQVNNVL C FPYIFRGALDV G A TTI N E EMKIA AVR A I A E LARE EQS D V VAAAY G G ED L S FGPDY L IP KP FDPRLI LKIA P A 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 405 VAQAAMD T GVA RK PI A DMDAYR AG L A Q RLDPTAGFLQKISGSVL A N PKR I VFAEGED PS V I RAA YAYQSG G FG K A IL C GR 484
Cdd:PRK12862 401 VAQAAMD S GVA TR PI E DMDAYR EQ L N Q FVYHSGLIMKPVFAAAK A A PKR V VFAEGED ER V L RAA QVVVDE G LA K P IL I GR 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 485 ENLVHENMKLV GL D - PDTAGL EI I N ARLSD R NP DY V D ALY A RLQ R Q G YLKRDVQ R LINQDRNSFA A S MV TL GEAD G M VT G 563
Cdd:PRK12862 481 PAVIEARIERA GL R l RPGVDF EI V N PEDDP R YR DY W D TYH A LMG R K G VTPEMAR R EVRRRTTLIG A M MV KR GEAD A M IC G 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 564 VTRSFDQA LE E VL R V VDPA PG G R - IMG MS VVLAK GRT I F V ADT N V T E L P E AEEL V EI ACE AA RA VRR L G FK P R VA FM S Y S 642
Cdd:PRK12862 561 TEGRYERH LE F VL Q V IGKR PG V R v YAA MS LLILP GRT L F L ADT H V N E D P T AEEL A EI TIL AA EE VRR F G IE P K VA LL S H S 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 643 T FG NPMGLRSE K V REA VAM L D E MEV D F E YE GEM PPEL ALD P E K R AN - Y P FM RL TDS AN I L IM P AIH AA S I STK L VQSLG G 721
Cdd:PRK12862 641 N FG SSDSPSAR K M REA LEI L R E RAP D L E VD GEM HGDA ALD E E L R DR i F P DS RL EGE AN L L VF P NLD AA N I AYN L LKTAA G 720
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 499223838 722 ATV - I GP V LLG LS K S V Q I APL SA S V SK I L NM AMM A AY D QPVD 762
Cdd:PRK12862 721 NGL a V GP I LLG AA K P V H I LTP SA T V RR I V NM TAL A VA D ANAY 762
SfcA
COG0281 Malic enzyme [Energy production and conversion]; Malic enzyme is part of the Pathway/BioSystem: ...
7-433
0e+00
Malic enzyme [Energy production and conversion]; Malic enzyme is part of the Pathway/BioSystem: Urea cycle
Pssm-ID: 440050 [Multi-domain]
Cd Length: 414
Bit Score: 699.46
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 7 S D A ER KTFTDA EAL AF HR YPTP GKI AIV PT K P MA TQ R DLSLAY S PGVA VPVHA IA A DP DM AY E YT S KGNLVAV ISN GTA I 86
Cdd:COG0281 1 E D M ER VETLEQ EAL EY HR IYDR GKI LVY PT V P LH TQ E DLSLAY T PGVA EACLE IA E DP RL AY G YT A KGNLVAV VTD GTA V 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 87 LGLGD L G A LA SK PVMEGK S VLFK R F GDV D SID I EVT T K DPDE IITV VK NIGV TFGGINLEDIK S P E CF R IE TE L Q E L LDI 166
Cdd:COG0281 81 LGLGD I G P LA GM PVMEGK A VLFK A F AGI D AFP I CLD T N DPDE FVEA VK ALEP TFGGINLEDIK A P N CF E IE ER L R E E LDI 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 167 PVFHDDQHGTAI ICA A G L I NA CHIT GKK I ED V K V V L NG P GAAGIA SLE L IK A M G VRA EN C I A VDSKG V LY R GRT e GM N QW 246
Cdd:COG0281 161 PVFHDDQHGTAI VVL A A L L NA LKLV GKK L ED Q K I V I NG A GAAGIA IAR L LV A A G LSE EN I I M VDSKG L LY E GRT - DL N PY 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 247 K SAH A VE T DK R ---- TLAEA VV GADV LL G L SA K GAFT P EM IA SMA PN P V IFA M ANP D PEITPE EV K RVRKD AI MG TGRSD 322
Cdd:COG0281 240 K REF A RD T NP R glkg TLAEA IK GADV FI G V SA P GAFT E EM VK SMA KR P I IFA L ANP T PEITPE DA K AWGDG AI VA TGRSD 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 323 YPNQVNNVL G FP Y IFRGALDVRA R R VNH EMK I A C A Q ALA M L AR E D vpdevaaayhgrql KF GPDYIIPS A FDPR LIWY V P 402
Cdd:COG0281 320 YPNQVNNVL I FP G IFRGALDVRA T R ITD EMK L A A A R ALA D L VD E E -------------- EL GPDYIIPS P FDPR VSPA V A 385
410 420 430
....*....|....*....|....*....|.
gi 499223838 403 PF VA Q AA MDT GVAR K PI A dm DA YR AG L AQ R L 433
Cdd:COG0281 386 AA VA K AA IES GVAR R PI D -- ED YR EA L EA R M 414
PRK12861
PRK12861 malic enzyme; Reviewed
19-758
0e+00
malic enzyme; Reviewed
Pssm-ID: 183798 [Multi-domain]
Cd Length: 764
Bit Score: 691.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 19 AL AF H RY PTPGKI AI V PT KP MA TQRDL S LAY S PGVA VPVHA IAADP DM A YEY TS K GNLV A VI S NGTA I LGLG DL GALASK 98
Cdd:PRK12861 11 AL DY H EF PTPGKI SV V AS KP LV TQRDL A LAY T PGVA SACEE IAADP LN A FRF TS R GNLV G VI T NGTA V LGLG NI GALASK 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 99 PVMEGK S VLFK R F GDV D SI DIE VTTK DPD EIITVVKNIGV TFGGINLEDIK S PECF RI E TE L Q E LLD IPVFHDDQHGTAI 178
Cdd:PRK12861 91 PVMEGK A VLFK K F AGI D VF DIE INET DPD KLVDIIAGLEP TFGGINLEDIK A PECF TV E RK L R E RMK IPVFHDDQHGTAI 170
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 179 ICA A GL IN ACHIT GK K I ED VKVV LN G P GAA GI A S L E L IKAM G VRA EN CIAV D SK GV L YRGRT EG M NQW K SAH A V ETD K RT 258
Cdd:PRK12861 171 TVS A AF IN GLKVV GK S I KE VKVV TS G A GAA AL A C L D L LVDL G LPV EN IWVT D IE GV V YRGRT TL M DPD K ERF A Q ETD A RT 250
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 259 LAE AVV GADV L LGLSA K G AFTP EM IAS MA PN P V I F A M ANP D PEI T PE EVKRV R K D AIMG TGRSDYPNQVNNVL G FPYIFR 338
Cdd:PRK12861 251 LAE VIG GADV F LGLSA G G VLKA EM LKA MA AR P L I L A L ANP T PEI F PE LAHAT R D D VVIA TGRSDYPNQVNNVL C FPYIFR 330
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 339 GALDV R A RRVNH EM K IA CAQ A L A M LA R E DVP D E VAAAY HGRQLK FGP D Y I IP SA FDPRLI WYVP P F VA Q AAM DT GVA RK P 418
Cdd:PRK12861 331 GALDV G A TTITR EM E IA AVH A I A G LA E E EQN D V VAAAY GAYDVS FGP Q Y L IP KP FDPRLI VRIA P A VA K AAM EG GVA TR P 410
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 419 IAD M DAY RAG L A Q RLDPTAG F LQKI --- SGSVLANP -- K RIVF A EGED PS V I RA AYAYQSGGFGKA IL C GR ENLVHENMK 493
Cdd:PRK12861 411 IAD L DAY VEQ L Q Q FVYHSGA F MKPL faa ARQLVRDG gk A RIVF T EGED ER V L RA VQVIVDEKLARP IL V GR PEVLLARIE 490
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 494 LV GL DPDTA - GL E II N ARLSD R N P D Y VDALYARLQ R Q G YL K RDVQRLINQDRNSFA A S MV T LG E ADGM VT G VTRSFDQA L 572
Cdd:PRK12861 491 RF GL RLRLG q DV E VT N PEYDE R F P Q Y WTTYWELRC R D G IS K EMARVEMRRRLTLIG A M MV R LG D ADGM IC G TVGEYHNH L 570
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 573 EE V LR V VDPA PG GRIMG - M SVV L AKG RT IFVA DT N V TEL P E AE ELV E IACE AAR AVRR L GFK P R VA FM S Y S T FG NPMGLR 651
Cdd:PRK12861 571 RF V DE V IGRK PG ASTYA a M NIL L LDQ RT VALV DT H V NDN P D AE QIA E FTIA AAR QMEW L NLT P K VA LL S R S N FG SGSAAS 650
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 652 SE K V R E A VAMLD E MEV D F E YE GEM PPEL ALD PEK RA NY - P FMR L TDS AN I L IM P AIH A AS I STK L VQSLG G AT V - I GP V L 729
Cdd:PRK12861 651 GV K M R R A LEIVR E QAP D L E AD GEM HGDC ALD EGL RA RL l P MSP L KGA AN L L VC P NVD A GN I AYN L LKTEA G SN V a V GP F L 730
730 740
....*....|....*....|....*....
gi 499223838 730 LG LSKS V Q I APL SA S V SK I L NMA MMAAYD 758
Cdd:PRK12861 731 LG VNAP V N I LTS SA T V RR I V NMA ALTVIE 759
Malic_M
smart00919 Malic enzyme, NAD binding domain; Malic enzymes (malate oxidoreductases) catalyse the ...
173-410
2.41e-116
Malic enzyme, NAD binding domain; Malic enzymes (malate oxidoreductases) catalyse the oxidative decarboxylation of malate to form pyruvate.
Pssm-ID: 214912
Cd Length: 231
Bit Score: 350.56
E-value: 2.41e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 173 Q H GTAI ICA AGL I NA CH ITGKK I ED VKV V L NG P GAAGI ASLE L IK A M GV RAE N CIA VDSKG V L YR GR TEGM N QW K SAH A V 252
Cdd:smart00919 1 Q Q GTAI VVL AGL L NA LK ITGKK L ED QRI V V NG A GAAGI GIAK L LV A A GV KRK N IWL VDSKG L L TK GR EDNL N PY K KPF A R 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 253 E T DK R --- TL A EAV V GADVL L G L S AK - GAFT P EM IA SMA PN P V IFA MA NP D PEI T P EEVKRV R K - D AI MG TGRSDYPNQV 327
Cdd:smart00919 81 K T NE R etg TL E EAV K GADVL I G V S GP g GAFT E EM VK SMA ER P I IFA LS NP T PEI E P TAADAY R W t A AI VA TGRSDYPNQV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 328 NNVL G FP Y IF R GALDVRARR VNH EMK I A C A Q AL amlaredvpdev A A A YHGRQLKF GP D YIIPS A FD P R LIWY V PPF VA Q 407
Cdd:smart00919 161 NNVL I FP G IF L GALDVRARR ITD EMK L A A A E AL ------------ A D A VPVSEEEL GP G YIIPS P FD R R VSAR V AVA VA K 228
...
gi 499223838 408 AA M 410
Cdd:smart00919 229 AA I 231
Pta
COG0280 Phosphotransacetylase (includes Pta, EutD and phosphobutyryltransferase) [Energy production ...
439-758
3.07e-109
Phosphotransacetylase (includes Pta, EutD and phosphobutyryltransferase) [Energy production and conversion];
Pssm-ID: 440049 [Multi-domain]
Cd Length: 320
Bit Score: 335.50
E-value: 3.07e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 439 F LQKISGSVL A N PKRIVFAEGED PS V I RAA YAYQSG G FGKA IL C GR ENLVHENMKLV GLD PD ta G L EII NARL S D R NPD Y 518
Cdd:COG0280 2 F FRPLIERAK A A PKRIVFAEGED ER V L RAA QEALDE G LAEP IL V GR PEKIEARAEEL GLD LS -- G F EII DPED S P R YEE Y 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 519 VD A L Y ARLQ R Q G YLKRDVQR L I n Q D RNS FAA S MV T LGEADG M V T G VTRSFDQA L EE VL RVVDPA PG GRIM - GMSVVLAKG 597
Cdd:COG0280 80 AE A Y Y ELRK R K G VTPEEARE L V - R D AAY FAA M MV R LGEADG L V K G AVGTTADL L RP VL QIIGLR PG VKRV s HVFLMELPD 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 598 R TI F VA DT N V TEL P E AE E L VE IA CE AA RAV R RL G FK P R VA FM S Y S T FG N P M G LRSE KVREA VA M LDEMEV D F E YE GE MPP 677
Cdd:COG0280 159 R LL F IT DT A V NID P T AE Q L AD IA IN AA DTA R AF G IE P K VA LL S A S E FG S P K G PSTD KVREA TK M ARGQIP D L E VD GE LQF 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 678 EL AL D PE KRA - NY P FMRLTDS AN I L IM P AIH A AS I ST KL V Q S L G GA TV IGP V LLGL S K S V QIAPLSA SV SK I L N MAMM AA 756
Cdd:COG0280 239 DA AL S PE AAK r KG P DSPVAGD AN V L VF P DLE A GN I LY KL L Q R L A GA EA IGP I LLGL A K P V HLLSRGD SV RD I V N SIAL AA 318
..
gi 499223838 757 YD 758
Cdd:COG0280 319 VQ 320
NAD_bind_2_malic_enz
cd05311 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Malic enzyme (ME), a member of the ...
173-409
2.33e-101
NAD(P) binding domain of malic enzyme (ME), subgroup 2; Malic enzyme (ME), a member of the amino acid dehydrogenase (DH)-like domain family, catalyzes the oxidative decarboxylation of L-malate to pyruvate in the presence of cations (typically Mg++ or Mn++) with the concomitant reduction of cofactor NAD+ or NADP+. ME has been found in all organisms, and plays important roles in diverse metabolic pathways such as photosynthesis and lipogenesis. This enzyme generally forms homotetramers. The conversion of malate to pyruvate by ME typically involves oxidation of malate to produce oxaloacetate, followed by decarboxylation of oxaloacetate to produce pyruvate and CO2. This subfamily consists primarily of archaeal and bacterial ME. Amino acid DH-like NAD(P)-binding domains are members of the Rossmann fold superfamily and include glutamate, leucine, and phenylalanine DHs, methylene tetrahydrofolate DH, methylene-tetrahydromethanopterin DH, methylene-tetrahydropholate DH/cyclohydrolase, Shikimate DH-like proteins, malate oxidoreductases, and glutamyl tRNA reductase. Amino acid DHs catalyze the deamination of amino acids to keto acids with NAD(P)+ as a cofactor. The NAD(P)-binding Rossmann fold superfamily includes a wide variety of protein families including NAD(P)- binding domains of alcohol DHs, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate DH, lactate/malate DHs, formate/glycerate DHs, siroheme synthases, 6-phosphogluconate DH, amino acid DHs, repressor rex, NAD-binding potassium channel domain, CoA-binding, and ornithine cyclodeaminase-like domains. These domains have an alpha-beta-alpha configuration. NAD binding involves numerous hydrogen and van der Waals contacts.
Pssm-ID: 133453 [Multi-domain]
Cd Length: 226
Bit Score: 311.51
E-value: 2.33e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 173 QHGTAI ICA AGL I NA CHIT GKKIE D VK V V L NG P GAAGIA SLE L IK A M G VRA EN CIA VDSKGV L Y R GR TEGM N QW K SAH A V 252
Cdd:cd05311 1 QHGTAI VTL AGL L NA LKLV GKKIE E VK I V I NG A GAAGIA IAR L LL A A G AKP EN IVV VDSKGV I Y E GR EDDL N PD K NEI A K 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 253 ET DKR ---- TL A EA VV GADV LL G L S AK G AFTP EMI AS MA PN P VI FA M ANP D PEI T PEE V K RVRK D a I MG TGRSD Y PNQVN 328
Cdd:cd05311 81 ET NPE ktgg TL K EA LK GADV FI G V S RP G VVKK EMI KK MA KD P IV FA L ANP V PEI W PEE A K EAGA D - I VA TGRSD F PNQVN 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 329 NVLGFP Y IFRGALDVRA RRVNH EMK I A C A Q A L A M LA R E D V P devaaayhgrqlkf G PD YIIP SA FDPR LIWY V PPF VA Q A 408
Cdd:cd05311 160 NVLGFP G IFRGALDVRA TKITE EMK L A A A E A I A D LA E E E V L -------------- G EE YIIP TP FDPR VVPR V ATA VA K A 225
.
gi 499223838 409 A 409
Cdd:cd05311 226 A 226
PTA_PTB
pfam01515 Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase ...
439-756
2.57e-90
Phosphate acetyl/butaryl transferase; This family contains both phosphate acetyltransferase and phosphate butaryltransferase. These enzymes catalyze the transfer of an acetyl or butaryl group to orthophosphate.
Pssm-ID: 396207 [Multi-domain]
Cd Length: 318
Bit Score: 286.13
E-value: 2.57e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 439 FL QK I SGSVLANP KRIVF A EGED PS V IR AA YAYQSG G FGKA IL C G R E N lv HENM K LV GLD P D TA G L EI INARL S D R NPD Y 518
Cdd:pfam01515 1 FL ER I FERAKKAK KRIVF P EGED ER V LK AA QKLLQQ G IADP IL I G D E I -- EIKA K AL GLD L D LD G I EI VDPET S P R LEE Y 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 519 V D AL Y ARLQ R Q G YLKRDVQR l I NQ D R N S FAA SM V T LGEADGMV T G VTRSFDQA L EEV L RVVDPA PG GRIM - GMSVV L AKG 597
Cdd:pfam01515 79 A D FY Y ELRK R K G MTPEIARE - I VR D P N Y FAA ML V K LGEADGMV S G AVNTTADT L RPA L QIIGTK PG VKTV s SVFIM L LPD 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 598 RTI F V AD TN V TEL P E AEEL V EIA CEA A RAVR R L G F - K PRVA FM SYSTFG NPM G LRS EKVREA VAMLD E MEV D FEYE GE MP 676
Cdd:pfam01515 158 GLL F F AD CA V NPN P T AEEL A EIA LMS A KTAK R F G I i E PRVA LL SYSTFG SGK G EDV EKVREA TKIVR E RAP D LVVD GE LQ 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 677 PEL AL DP E KR A N - Y P FMRLTDS AN ILIM P AIH A AS I ST K LV Q S LGGA TV IGP V L L GL S K S V QIAPLS ASV SK I L N M A MMA 755
Cdd:pfam01515 238 FDA AL VE E VA A Q k A P DSPVAGK AN VFVF P DLE A GN I GY K IA Q R LGGA EA IGP I L Q GL A K P V NDLSRG ASV ED I V N T A AIT 317
.
gi 499223838 756 A 756
Cdd:pfam01515 318 A 318
eutD
PRK09653 phosphotransacetylase;
439-756
9.98e-51
phosphotransacetylase;
Pssm-ID: 236609 [Multi-domain]
Cd Length: 324
Bit Score: 180.43
E-value: 9.98e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 439 FLQKISGSVLANP K R IV FA EGED PS V IR AA YAY Q SG G FGKA IL C G RENLVHENM K LV GLD P D ta G L EII NARLSDRNPDY 518
Cdd:PRK09653 3 LFESLKEKAKGKK K K IV LP EGED ER V LK AA KRL Q KE G LVEP IL L G NPEEIRAKA K EL GLD L D -- G V EII DPETYPLLEEF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 519 VD A LYAR lq R Q G YLKRDVQRLINQ D R N S F AASM V T LG E ADGMV T G VTR S FDQA L EEV L RVVDPA PG GRIMGMSVVLA KG - 597
Cdd:PRK09653 81 AE A FVEL -- R K G KGTEEDAAELLK D P N Y F GTML V K LG K ADGMV S G AIH S TADT L RPA L QIIKTK PG VKTVSSVFIMV KG d 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 598 - R T IF v AD TN V TEL P E AE E L V EIA CEA A RAVRRL G FK P R VA FM S Y ST F G NPM G LRSE KV R EA VAMLD E MEV D FEYE GE MP 676
Cdd:PRK09653 159 e R Y IF - AD CA V NPN P T AE Q L A EIA INS A ETAKAF G ID P K VA ML S F ST K G SAK G PEVD KV Q EA TEIAK E LAP D LKID GE LQ 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 677 PEL A LD PE KR A - NY P FMRLTDS AN ILIM P AIH A AS I ST K LV Q S LGG ATVI GP V L L GL S K S V qi AP LS -- A SV SK I L N M A M 753
Cdd:PRK09653 238 FDA A FV PE VA A k KA P GSPVAGK AN VFVF P SLE A GN I GY K IA Q R LGG FEAV GP I L Q GL N K P V -- ND LS rg C SV ED I Y N L A L 315
...
gi 499223838 754 MA A 756
Cdd:PRK09653 316 IT A 318
PLN03129
PLN03129 NADP-dependent malic enzyme; Provisional
77-425
6.75e-36
NADP-dependent malic enzyme; Provisional
Pssm-ID: 215594 [Multi-domain]
Cd Length: 581
Bit Score: 143.51
E-value: 6.75e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 77 V A V ISN G TA ILGLGDLG ALA skpv M --- E GK SV L FKRF G DVD ----- SID I E V T T ------ K DP ---------------- 126
Cdd:PLN03129 174 V I V VTD G ER ILGLGDLG VQG ---- M gip V GK LD L YTAA G GIR psavl PVC I D V G T nnekll N DP fyiglrqprltgeeyd 249
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 127 --- DE IITV VK N igv TF G G --- INL ED IKSPEC FR I ete LQ ELLD - IPV F H DD QH GTA IICA AGL IN A CHI TG KKIE D VK 199
Cdd:PLN03129 250 elv DE FMEA VK Q --- RW G P kvl VQF ED FANKNA FR L --- LQ RYRT t HLC F N DD IQ GTA AVAL AGL LA A LRA TG GDLA D QR 323
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 200 VVLN G P G A AG IASL ELI ----- KAM G VRA E ---- NCIA VDSKG VLYRG R TEGMNQW K S -- AH AV E t DKRT L A EAV -- VGA 266
Cdd:PLN03129 324 ILFA G A G E AG TGIA ELI alams RQT G ISE E eark RIWL VDSKG LVTKS R KDSLQPF K K pf AH DH E - PGAS L L EAV ka IKP 402
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 267 D VL L GLS AK G - A FT P E MIAS MA --- PN P V IFA MA NP -- DP E I T P EE VKRVRK ----------- D AIMGT G RSDY P N Q V NN 329
Cdd:PLN03129 403 T VL I GLS GV G g T FT K E VLEA MA sln ER P I IFA LS NP ts KA E C T A EE AYTWTG graifasgspf D PVEYN G KTFH P G Q A NN 482
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 330 VLG FP Y I FR GAL DVR A R RV NHE M KI A C A Q ALA - MLAR E DV pd EVA A A Y hgrqlkfgpdyiipsafdprliwyv PPF ---- 404
Cdd:PLN03129 483 AYI FP G I GL GAL LSG A I RV TDD M LL A A A E ALA a QVTE E EL -- AKG A I Y ------------------------- PPF srir 535
410 420 430
....*....|....*....|....*....|..
gi 499223838 405 --------- VA QA A MDT G V A RKP -- IA D MDA Y 425
Cdd:PLN03129 536 disahvaaa VA AK A YEE G L A TRL pr PE D LVE Y 567
malic
pfam00390 Malic enzyme, N-terminal domain;
28-157
5.29e-34
Malic enzyme, N-terminal domain;
Pssm-ID: 395314 [Multi-domain]
Cd Length: 182
Bit Score: 128.53
E-value: 5.29e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 28 P GK IAIVPT K PMA T Q -- R DL SLA Y S P G V AVPVH AI AADPDMAY - E YTS K GNL ---------------- V A V ISN G TA ILG 88
Cdd:pfam00390 1 Q GK NEVLFY K LLS T H ie E DL PIV Y T P T V GEACQ AI SEIYRRPR g L YTS I GNL gkikdilknwpeedvr V I V VTD G ER ILG 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 89 LGDLG A l A SK P V MEGK SV L FKR F GDV D --- SID I EVTTK --------------------------- DP DE IITV VK NIGV 138
Cdd:pfam00390 81 LGDLG V - A GM P I MEGK LA L YTA F AGI D psr VLP I VLDVG tnnekllndplylglrhkrvrgeeyde FV DE FVEA VK ALFP 159
170
....*....|....*....
gi 499223838 139 T FGGI NL ED IKS P EC F R I E 157
Cdd:pfam00390 160 P FGGI QF ED FGA P NA F E I L 178
Malic_M
pfam03949 Malic enzyme, NAD binding domain;
175-371
2.60e-32
Malic enzyme, NAD binding domain;
Pssm-ID: 427608 [Multi-domain]
Cd Length: 257
Bit Score: 126.15
E-value: 2.60e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 175 GTA IICA AGL IN A CH ITGK KIEDVKV V LN G P G A AGI ASLEL I KAMG VR -------- AENCIA VD SK G V L YRG R ------- 239
Cdd:pfam03949 3 GTA AVAL AGL LA A LK ITGK PLSEQRI V FF G A G S AGI GIADQ I RDAM VR eglseeea RKRIWM VD RQ G L L TDD R edltdfq 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 240 ------ TEGMNQ W K sahavet D KR TL A E A V -- V GAD VL L G L S A - K GAFT P E MIAS MA --- PN P V IF AMA NP DP -- E I TPE 305
Cdd:pfam03949 83 kpfark RAELKG W G ------- D GI TL L E V V rk V KPT VL I G A S G v P GAFT E E IVRA MA aht ER P I IF PLS NP TS ka E A TPE 155
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499223838 306 EVKRVRK - D A IMG TG ---------- RSDYPN Q V NN VLG FP YIFR GA LDV RARR VNH EM KI A C A Q ALA MLAR E DV P DE 371
Cdd:pfam03949 156 DAYKWTD g R A LFA TG spfppveyng KTYHIG Q G NN AYI FP GLGL GA IVS RARR ITD EM FL A A A E ALA SYVD E EE P GQ 232
PTZ00317
PTZ00317 NADP-dependent malic enzyme; Provisional
77-368
5.02e-32
NADP-dependent malic enzyme; Provisional
Pssm-ID: 240357 [Multi-domain]
Cd Length: 559
Bit Score: 131.67
E-value: 5.02e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 77 V A VI SN G TA ILGLGDLGA l ASKPVME GK SV L FKRF G DVD ------- SI D IEVTTK ---- DP ------------------- 126
Cdd:PTZ00317 151 V I VI TD G SR ILGLGDLGA - NGMGISI GK LS L YVAG G GIN psrvlpv VL D VGTNNE klln DP lylglrekrldddeyyell 229
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 127 DE IITV V K ---- N IG V T F gginl ED IKSPE CF RIETEL Q EL ld IPV F H DD QH GT AIIC AAG LI NA CHIT G KKI E DVKV V L 202
Cdd:PTZ00317 230 DE FMEA V S srwp N AV V Q F ----- ED FSNNH CF DLLERY Q NK -- YRC F N DD IQ GT GAVI AAG FL NA LKLS G VPP E EQRI V F 302
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 203 N G P G A A G I ASLEL I KAMGVRAENCIA -------- VDSKG VLYRG R TEGMNQW K SAH A VE ------ TDKR TL AEA V -- V GA 266
Cdd:PTZ00317 303 F G A G S A A I GVANN I ADLAAEYGVTRE ealksfyl VDSKG LVTTT R GDKLAKH K VPF A RT disaed SSLK TL EDV V rf V KP 382
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 267 DV LLGLS AK G - A FT P E MIAS MA --- PN P V IF AMA NP -- DP E I T P E EV - K RVRKD AI MGT G ---------- RSDY P N Q V NN 329
Cdd:PTZ00317 383 TA LLGLS GV G g V FT E E VVKT MA snv ER P I IF PLS NP ts KA E C T A E DA y K WTNGR AI VAS G spfppvtlng KTIQ P S Q G NN 462
330 340 350
....*....|....*....|....*....|....*....
gi 499223838 330 VLG FP YIFR G ALDVRARRVNH EM K IA C A QA LA M L AR E DV 368
Cdd:PTZ00317 463 LYV FP GVGL G CAIAQPSYIPD EM L IA A A AS LA T L VS E ED 501
PRK13529
PRK13529 oxaloacetate-decarboxylating malate dehydrogenase;
165-421
3.52e-31
oxaloacetate-decarboxylating malate dehydrogenase;
Pssm-ID: 237414 [Multi-domain]
Cd Length: 563
Bit Score: 129.10
E-value: 3.52e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 165 D I PV F H DD QH GT AIICA AGL IN A CH ITG KKIE D VKV V LN G P G A A -- GIA SL e LIK AM --- G VRA E ---- NCIA VD SK G V L 235
Cdd:PRK13529 263 E I CT F N DD IQ GT GAVTL AGL LA A LK ITG EPLS D QRI V FL G A G S A gc GIA DQ - IVA AM vre G LSE E eark RFFM VD RQ G L L 341
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 236 yrgr T EG M N ----- Q WKS A H -------- AV E T D KRT L A E A V -- V GAD VL L G L S AK - GAFT P E MIAS MA --- PN P V IF AMA 296
Cdd:PRK13529 342 ---- T DD M P dlldf Q KPY A R kreeladw DT E G D VIS L L E V V rn V KPT VL I G V S GQ p GAFT E E IVKE MA ahc ER P I IF PLS 417
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 297 NP DP -- E I TPE EVKRVRK - D A IMG TG ---------- RSDYPN Q V NN VLG FP YIFR G ALDVR ARRV NHE M KI A C A Q ALA ML 363
Cdd:PRK13529 418 NP TS ra E A TPE DLIAWTD g R A LVA TG spfapveyng KTYPIG Q C NN AYI FP GLGL G VIASG ARRV TDG M LM A A A H ALA DC 497
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499223838 364 AREDV P D E ---------------- V A A A yhgrqlkfgpdyiipsafdprliwyvppf VA Q AA MDT G V AR KPIAD 421
Cdd:PRK13529 498 VPLAK P G E gallppvedirevsra I A I A ----------------------------- VA K AA IEE G L AR ETSDE 542
NAD_bind_malic_enz
cd00762 NAD(P) binding domain of malic enzyme; Malic enzyme (ME), a member of the amino acid ...
173-398
5.32e-29
NAD(P) binding domain of malic enzyme; Malic enzyme (ME), a member of the amino acid dehydrogenase (DH)-like domain family, catalyzes the oxidative decarboxylation of L-malate to pyruvate in the presence of cations (typically Mg++ or Mn++) with the concomitant reduction of cofactor NAD+ or NADP+. ME has been found in all organisms and plays important roles in diverse metabolic pathways such as photosynthesis and lipogenesis. This enzyme generally forms homotetramers. The conversion of malate to pyruvate by ME typically involves oxidation of malate to produce oxaloacetate, followed by decarboxylation of oxaloacetate to produce pyruvate and CO2. Amino acid DH-like NAD(P)-binding domains are members of the Rossmann fold superfamily and include glutamate, leucine, and phenylalanine DHs, methylene tetrahydrofolate DH, methylene-tetrahydromethanopterin DH, methylene-tetrahydropholate DH/cyclohydrolase, Shikimate DH-like proteins, malate oxidoreductases, and glutamyl tRNA reductase. Amino acid DHs catalyze the deamination of amino acids to keto acids with NAD(P)+ as a cofactor. The NAD(P)-binding Rossmann fold superfamily includes a wide variety of protein families including NAD(P)- binding domains of alcohol DHs, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate DH, lactate/malate DHs, formate/glycerate DHs, siroheme synthases, 6-phosphogluconate DH, amino acid DHs, repressor rex, NAD-binding potassium channel domain, CoA-binding, and ornithine cyclodeaminase-like domains. These domains have an alpha-beta-alpha configuration. NAD binding involves numerous hydrogen and van der Waals contacts.
Pssm-ID: 133442
Cd Length: 254
Bit Score: 116.55
E-value: 5.32e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 173 QH GTA IICA AGL IN A CHI T G KKI EDV KV VL NG P GAA GIASLE LI KAMG V R -------- AENCIA VD S KG V L YRG R T E GMN 244
Cdd:cd00762 1 IQ GTA SVAV AGL LA A LKV T K KKI SEH KV LF NG A GAA ALGIAN LI V*L* V K egiskeea CKRIW* VD R KG L L VKN R K E TCP 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 245 QWKSAHAVETDK R --- T L AE AV -- VGA D V L L G L S AK G - AFTPE M I --- A SMAPN PVIFA MA NP DP -- E I T P EE VKRVRK - 312
Cdd:cd00762 81 NEYHLARFANPE R esg D L ED AV ea AKP D F L I G V S RV G g AFTPE V I ra* A EINER PVIFA LS NP TS ka E C T A EE AYTATE g 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 313 D AI MGT G RSD ---------- Y P N Q V NN VLG FP YIFR G ALDV R A R RVNHEMKIAC A Q A lam L A REDVPDEVA aayhgrqlk 382
Cdd:cd00762 161 R AI FAS G SPF hpvelnggty K P G Q G NN LYI FP GVAL G VILC R I R HITDDVFLSA A E A --- I A SSVTEESLK --------- 228
250
....*....|....*.
gi 499223838 383 fg P DYII P SA FD PRLI 398
Cdd:cd00762 229 -- P GRLY P PL FD IQEV 242
PRK05632
PRK05632 phosphate acetyltransferase; Reviewed
449-736
1.77e-21
phosphate acetyltransferase; Reviewed
Pssm-ID: 235537 [Multi-domain]
Cd Length: 684
Bit Score: 99.84
E-value: 1.77e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 449 A NP KRIV FA EG ED P SVIR AA YAYQSG G FGKAI L C G RENLVHENMKLV G L D - P D ta G L EII NA rl S DRNPD YV DA L YARLQ 527
Cdd:PRK05632 375 A AK KRIV LP EG DE P RTLK AA AICLER G IADCV L L G NPEEIRRVAAAQ G V D l P A -- G I EII DP -- S EVRER YV AP L VELRK 450
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 528 RQ G y LKRD V Q R LINQ D RNS F AAS M VT LGE A DG M V T G VTRSFDQALEEV L RVVDP APG GRIMG m SV -------- VL AK G rt 599
Cdd:PRK05632 451 HK G - MTEE V A R EQLE D NVY F GTM M LA LGE V DG L V S G AVHTTANTIRPA L QLIKT APG SSLVS - SV ffmllpdq VL VY G -- 526
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499223838 600 ifva D TN V TEL P E AE E L V EIA CEA A RAVRRL G FK PRVA FM SYST FGNPM G LRS EKVREA VAMLD E MEV D FEYE G EMPPEL 679
Cdd:PRK05632 527 ---- D CA V NPD P T AE Q L A EIA IQS A DSAAAF G IE PRVA ML SYST GTSGS G ADV EKVREA TRLAR E RRP D LLID G PLQYDA 602
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499223838 680 A L DP EKRA nypf MRLTD S ----- A NIL I M P AIHAASIST K L VQ SLG GA TV IGP V L L GL S K S V 736
Cdd:PRK05632 603 A V DP SVAR ---- SKAPN S pvagr A TVF I F P DLNTGNTTY K A VQ RSA GA VS IGP M L Q GL R K P V 660
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
