|
Name |
Accession |
Description |
Interval |
E-value |
| COG2945 |
COG2945 |
Alpha/beta superfamily hydrolase [General function prediction only]; |
7-196 |
9.64e-74 |
|
Alpha/beta superfamily hydrolase [General function prediction only];
Pssm-ID: 442188 [Multi-domain] Cd Length: 201 Bit Score: 221.57 E-value: 9.64e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 7 PLFIDGPSGQLEALY-LDVANARGAVLICHPNPVQGGTMLNKVVSTLQRTARDAGYVTLRFNYRGVGQSAGSHDMGAGEV 85
Cdd:COG2945 1 KVLINGPAGRLEGRLdLPEGPPRGVALILHPHPLFGGTMDNKVVYTLARALVAAGFAVLRFNFRGVGRSEGEFDEGRGEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 86 ADAEAAAAWLRARHPgLPLVLMGFSFGGFVATSLAGRLEtagvELQHLFMIAPAVMRLTAEFPMPQRCPLTVVQPDADEV 165
Cdd:COG2945 81 DDAAAALDWLRAQNP-LPLWLAGFSFGAYVALQLAMRLP----EVEGLILVAPPVNRYDFSFLAPCPAPTLVIHGEQDEV 155
|
170 180 190
....*....|....*....|....*....|.
gi 499254893 166 VAPQLVYEWSDSLSRPHELLKVAECGHFFHG 196
Cdd:COG2945 156 VPPAEVLDWARPLSPPLPVVVVPGADHFFHG 186
|
|
| Thioesterase |
pfam00975 |
Thioesterase domain; Peptide synthetases are involved in the non-ribosomal synthesis of ... |
95-167 |
5.03e-06 |
|
Thioesterase domain; Peptide synthetases are involved in the non-ribosomal synthesis of peptide antibiotics. Next to the operons encoding these enzymes, in almost all cases, are genes that encode proteins that have similarity to the type II fatty acid thioesterases of vertebrates. There are also modules within the peptide synthetases that also share this similarity. With respect to antibiotic production, thioesterases are required for the addition of the last amino acid to the peptide antibiotic, thereby forming a cyclic antibiotic. Thioesterases (non-integrated) have molecular masses of 25-29 kDa.
Pssm-ID: 395776 [Multi-domain] Cd Length: 223 Bit Score: 45.46 E-value: 5.03e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499254893 95 LRARHPGLPLVLMGFSFGGFVATSLAGRLETAGVELQHLFMI---APAVMRLTAEFPmpqrcpltvvqPDADEVVA 167
Cdd:pfam00975 58 LRQIQPEGPYALFGHSMGGMLAFEVARRLERQGEAVRSLFLSdasAPHTVRYEASRA-----------PDDDEVVA 122
|
|
| hydr2_PEP |
TIGR03101 |
exosortase A system-associated hydrolase 2; This group of proteins are members of the alpha ... |
7-125 |
1.63e-04 |
|
exosortase A system-associated hydrolase 2; This group of proteins are members of the alpha/beta hydrolase superfamily. These proteins are generally found in genomes containing the exosortase/PEP-CTERM protein expoert system, specifically the type 1 variant of this system described by the Genome Property GenProp0652. When found in this context they are invariably present in the vicinity of a second, relatively unrelated enzyme (ortholog 1, TIGR03100) of the same superfamily.
Pssm-ID: 274428 Cd Length: 266 Bit Score: 41.34 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 7 PLFIDGPSGQLEALYLD-VAN-ARGAVLICHPNpvqgGTMLNK---VVSTLQRTARDAGYVTLRFNYRGVGQSAGshDMG 81
Cdd:TIGR03101 2 PFFLDAPHGFRFCLYHPpVAVgPRGVVIYLPPF----AEEMNKsrrMVALQARAFAAGGFGVLQIDLYGCGDSAG--DFA 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 499254893 82 AGE----VADAEAAAAWLRARHPGlPLVLMGFSFGGFVATSLAGRLET 125
Cdd:TIGR03101 76 AARwdvwKEDVAAAYRWLIEQGHP-PVTLWGLRLGALLALDAANPLAA 122
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG2945 |
COG2945 |
Alpha/beta superfamily hydrolase [General function prediction only]; |
7-196 |
9.64e-74 |
|
Alpha/beta superfamily hydrolase [General function prediction only];
Pssm-ID: 442188 [Multi-domain] Cd Length: 201 Bit Score: 221.57 E-value: 9.64e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 7 PLFIDGPSGQLEALY-LDVANARGAVLICHPNPVQGGTMLNKVVSTLQRTARDAGYVTLRFNYRGVGQSAGSHDMGAGEV 85
Cdd:COG2945 1 KVLINGPAGRLEGRLdLPEGPPRGVALILHPHPLFGGTMDNKVVYTLARALVAAGFAVLRFNFRGVGRSEGEFDEGRGEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 86 ADAEAAAAWLRARHPgLPLVLMGFSFGGFVATSLAGRLEtagvELQHLFMIAPAVMRLTAEFPMPQRCPLTVVQPDADEV 165
Cdd:COG2945 81 DDAAAALDWLRAQNP-LPLWLAGFSFGAYVALQLAMRLP----EVEGLILVAPPVNRYDFSFLAPCPAPTLVIHGEQDEV 155
|
170 180 190
....*....|....*....|....*....|.
gi 499254893 166 VAPQLVYEWSDSLSRPHELLKVAECGHFFHG 196
Cdd:COG2945 156 VPPAEVLDWARPLSPPLPVVVVPGADHFFHG 186
|
|
| PldB |
COG2267 |
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism]; |
20-195 |
4.60e-17 |
|
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
Pssm-ID: 441868 [Multi-domain] Cd Length: 221 Bit Score: 76.19 E-value: 4.60e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 20 LYLDVANARGAVLICHpnpvqGGTMLNKVVSTLQRTARDAGYVTLRFNYRGVGQSAGSHDMGAGEVADAEAAAAWLRA-- 97
Cdd:COG2267 20 RWRPAGSPRGTVVLVH-----GLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFDDYVDDLRAALDAlr 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 98 RHPGLPLVLMGFSFGGFVATSLAGRletAGVELQHLFMIAPAVM---------RLTAEFPMPQ-----RCPLTVVQPDAD 163
Cdd:COG2267 95 ARPGLPVVLLGHSMGGLIALLYAAR---YPDRVAGLVLLAPAYRadpllgpsaRWLRALRLAEalariDVPVLVLHGGAD 171
|
170 180 190
....*....|....*....|....*....|..
gi 499254893 164 EVVAPQLVYEWSDSLSRPHELLKVAECGHFFH 195
Cdd:COG2267 172 RVVPPEAARRLAARLSPDVELVLLPGARHELL 203
|
|
| DAP2 |
COG1506 |
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]; |
28-196 |
3.11e-11 |
|
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
Pssm-ID: 441115 [Multi-domain] Cd Length: 234 Bit Score: 60.42 E-value: 3.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 28 RGAVLICHPNPVQGGTMLNKVVSTLqrtaRDAGYVTLRFNYRGVGQSAGshDMGAGEVADAEAAAAWLRARhPGLP---L 104
Cdd:COG1506 23 YPVVVYVHGGPGSRDDSFLPLAQAL----ASRGYAVLAPDYRGYGESAG--DWGGDEVDDVLAAIDYLAAR-PYVDpdrI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 105 VLMGFSFGGFVATSLAGR-------------------LETAGVELQHLFMIAPAVMRLTAEFPMPQ------RCPLTVVQ 159
Cdd:COG1506 96 GIYGHSYGGYMALLAAARhpdrfkaavalagvsdlrsYYGTTREYTERLMGGPWEDPEAYAARSPLayadklKTPLLLIH 175
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 499254893 160 PDADEVVAPQLVYEWSDSLSR---PHELLKVAECGHFFHG 196
Cdd:COG1506 176 GEADDRVPPEQAERLYEALKKagkPVELLVYPGEGHGFSG 215
|
|
| FrsA |
COG1073 |
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ... |
20-193 |
2.26e-09 |
|
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];
Pssm-ID: 440691 [Multi-domain] Cd Length: 253 Bit Score: 55.69 E-value: 2.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 20 LYL--DVANARGAVLICHPNpvqGGTMLNkvVSTLQRTARDAGYVTLRFNYRGVGQSAGS-HDMGAGEVADAEAAAAWLR 96
Cdd:COG1073 27 LYLpaGASKKYPAVVVAHGN---GGVKEQ--RALYAQRLAELGFNVLAFDYRGYGESEGEpREEGSPERRDARAAVDYLR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 97 AR--HPGLPLVLMGFSFGGFVATSLAGR--------LETAGVELQHLF---------MIAPAV---------MRLTAEF- 147
Cdd:COG1073 102 TLpgVDPERIGLLGISLGGGYALNAAATdprvkaviLDSPFTSLEDLAaqrakeargAYLPGVpylpnvrlaSLLNDEFd 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 499254893 148 PMPQ----RCPLTVVQPDADEVVAPQLVYEWSDSLSRPHELLKVAECGHF 193
Cdd:COG1073 182 PLAKiekiSRPLLFIHGEKDEAVPFYMSEDLYEAAAEPKELLIVPGAGHV 231
|
|
| Thioesterase |
pfam00975 |
Thioesterase domain; Peptide synthetases are involved in the non-ribosomal synthesis of ... |
95-167 |
5.03e-06 |
|
Thioesterase domain; Peptide synthetases are involved in the non-ribosomal synthesis of peptide antibiotics. Next to the operons encoding these enzymes, in almost all cases, are genes that encode proteins that have similarity to the type II fatty acid thioesterases of vertebrates. There are also modules within the peptide synthetases that also share this similarity. With respect to antibiotic production, thioesterases are required for the addition of the last amino acid to the peptide antibiotic, thereby forming a cyclic antibiotic. Thioesterases (non-integrated) have molecular masses of 25-29 kDa.
Pssm-ID: 395776 [Multi-domain] Cd Length: 223 Bit Score: 45.46 E-value: 5.03e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499254893 95 LRARHPGLPLVLMGFSFGGFVATSLAGRLETAGVELQHLFMI---APAVMRLTAEFPmpqrcpltvvqPDADEVVA 167
Cdd:pfam00975 58 LRQIQPEGPYALFGHSMGGMLAFEVARRLERQGEAVRSLFLSdasAPHTVRYEASRA-----------PDDDEVVA 122
|
|
| COG4757 |
COG4757 |
Predicted alpha/beta hydrolase [General function prediction only]; |
59-128 |
1.94e-05 |
|
Predicted alpha/beta hydrolase [General function prediction only];
Pssm-ID: 443790 [Multi-domain] Cd Length: 289 Bit Score: 44.10 E-value: 1.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 59 AGYVTLRFNYRGVGQSA--------------GSHDMGagevadaeAAAAWLRARHPGLPLVLMGFSFGGFVATSLAGRLE 124
Cdd:COG4757 58 RGFAVLTYDYRGIGLSRpgslrgfdagyrdwGELDLP--------AVLDALRARFPGLPLLLVGHSLGGQLLGLAPNAER 129
|
....
gi 499254893 125 TAGV 128
Cdd:COG4757 130 VDRL 133
|
|
| DLH |
COG0412 |
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism]; |
3-195 |
1.25e-04 |
|
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 440181 [Multi-domain] Cd Length: 226 Bit Score: 41.49 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 3 VRETPLFIDGPSGQLEALYL---DVANARGAVLICHPNpvqGGtmlnkVVSTLQRTAR---DAGYVTLRFNYRGVGQSAG 76
Cdd:COG0412 1 MTTETVTIPTPDGVTLPGYLarpAGGGPRPGVVVLHEI---FG-----LNPHIRDVARrlaAAGYVVLAPDLYGRGGPGD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 77 SHDMGAGEVADAEAAAA---------WLRAR--HPGLPLVLMGFSFGGFVATSLAGRL-ETAGVELQHLFMIAPAVMRLT 144
Cdd:COG0412 73 DPDEARALMGALDPELLaadlraaldWLKAQpeVDAGRVGVVGFCFGGGLALLAAARGpDLAAAVSFYGGLPADDLLDLA 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 499254893 145 AEFpmpqRCPLTVVQPDADEVVAPQLVYEWSDSLSR---PHELLKVAECGHFFH 195
Cdd:COG0412 153 ARI----KAPVLLLYGEKDPLVPPEQVAALEAALAAagvDVELHVYPGAGHGFT 202
|
|
| hydr2_PEP |
TIGR03101 |
exosortase A system-associated hydrolase 2; This group of proteins are members of the alpha ... |
7-125 |
1.63e-04 |
|
exosortase A system-associated hydrolase 2; This group of proteins are members of the alpha/beta hydrolase superfamily. These proteins are generally found in genomes containing the exosortase/PEP-CTERM protein expoert system, specifically the type 1 variant of this system described by the Genome Property GenProp0652. When found in this context they are invariably present in the vicinity of a second, relatively unrelated enzyme (ortholog 1, TIGR03100) of the same superfamily.
Pssm-ID: 274428 Cd Length: 266 Bit Score: 41.34 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 7 PLFIDGPSGQLEALYLD-VAN-ARGAVLICHPNpvqgGTMLNK---VVSTLQRTARDAGYVTLRFNYRGVGQSAGshDMG 81
Cdd:TIGR03101 2 PFFLDAPHGFRFCLYHPpVAVgPRGVVIYLPPF----AEEMNKsrrMVALQARAFAAGGFGVLQIDLYGCGDSAG--DFA 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 499254893 82 AGE----VADAEAAAAWLRARHPGlPLVLMGFSFGGFVATSLAGRLET 125
Cdd:TIGR03101 76 AARwdvwKEDVAAAYRWLIEQGHP-PVTLWGLRLGALLALDAANPLAA 122
|
|
| Hydrolase_4 |
pfam12146 |
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ... |
25-122 |
1.70e-04 |
|
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.
Pssm-ID: 463473 [Multi-domain] Cd Length: 238 Bit Score: 41.05 E-value: 1.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 25 ANARGAVLICHpnpvqgGtmLNKVVSTLQRTARD---AGYVTLRFNYRGVGQSAGSH-----------DMGAGEVAdaea 90
Cdd:pfam12146 1 GEPRAVVVLVH------G--LGEHSGRYAHLADAlaaQGFAVYAYDHRGHGRSDGKRghvpsfddyvdDLDTFVDK---- 68
|
90 100 110
....*....|....*....|....*....|..
gi 499254893 91 aaawLRARHPGLPLVLMGFSFGGFVATSLAGR 122
Cdd:pfam12146 69 ----IREEHPGLPLFLLGHSMGGLIAALYALR 96
|
|
| Abhydrolase_1 |
pfam00561 |
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes. |
29-122 |
2.95e-04 |
|
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
Pssm-ID: 395444 [Multi-domain] Cd Length: 245 Bit Score: 40.57 E-value: 2.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 29 GAVLICHpnpvqGGTMLNKVVSTLQRTARDAGYVTLRFNYRGVGQSAGSHDMGAGEVADAEAAAAWLRARHPGLPLVLMG 108
Cdd:pfam00561 1 PPVLLLH-----GLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQDDYRTDDLAEDLEYILEALGLEKVNLVG 75
|
90
....*....|....
gi 499254893 109 FSFGGFVATSLAGR 122
Cdd:pfam00561 76 HSMGGLIALAYAAK 89
|
|
| MenH |
COG0596 |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ... |
21-195 |
7.94e-04 |
|
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440361 [Multi-domain] Cd Length: 221 Bit Score: 39.21 E-value: 7.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 21 YLDVANARGAVLICHPNPvQGGTMLNKVVSTLQrtardAGYVTLRFNYRGVGQSAGSHDmgageVADAEAAAAWLRA--R 98
Cdd:COG0596 16 YREAGPDGPPVVLLHGLP-GSSYEWRPLIPALA-----AGYRVIAPDLRGHGRSDKPAG-----GYTLDDLADDLAAllD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 99 HPGL-PLVLMGFSFGGFVATSLAGRLETAgveLQHLFMIAPAVMRLTAEFPMPQ-------------------------R 152
Cdd:COG0596 85 ALGLeRVVLVGHSMGGMVALELAARHPER---VAGLVLVDEVLAALAEPLRRPGlapealaallralartdlrerlariT 161
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 499254893 153 CPLTVVQPDADEVVAPQLVYEWSDSLSRpHELLKVAECGHFFH 195
Cdd:COG0596 162 VPTLVIWGEKDPIVPPALARRLAELLPN-AELVVLPGAGHFPP 203
|
|
| GrsT |
COG3208 |
Surfactin synthase thioesterase subunit [Secondary metabolites biosynthesis, transport and ... |
97-195 |
8.49e-04 |
|
Surfactin synthase thioesterase subunit [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442441 [Multi-domain] Cd Length: 237 Bit Score: 39.06 E-value: 8.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499254893 97 ARHPGLPLVLMGFSFGGFVATSLAGRLETAGVEL-QHLF----------------------------------------- 134
Cdd:COG3208 67 APLLDRPFALFGHSMGALLAFELARRLERRGRPLpAHLFvsgrraphlprrrrplhdlsdaellaelrrlggtpeevlad 146
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499254893 135 -----MIAPAV---MRLTAEFPMPQ----RCPLTVVQPDADEVVAPQLVYEWSDSLSRPHElLKVAECGHFFH 195
Cdd:COG3208 147 pelleLFLPILradFRLLETYRYTPgpplDCPITALGGDDDPLVSPEELAAWREHTTGPFR-LRVFPGGHFFL 218
|
|
| |
