|
Name |
Accession |
Description |
Interval |
E-value |
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
1-856 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1560.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 1 MKSAEIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLGAEKRAYTRAVSSQKCVRAGGKHNDLENVG 80
Cdd:COG0013 2 MTSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPYPRATTSQKCVRTGGKHNDLENVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 81 YTARHHTFFEMLGNFSFGDYFKRDAITFAWTFLTseQWLNLPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGdnkg 160
Cdd:COG0013 82 YTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLT--EVLGLPKERLWVTVYEDDDEAYDIWKKEIGVPEERIIRLG---- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 161 apyASDNFWTMGDTGPCGPCTEIFYDHGPDIWGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLE 240
Cdd:COG0013 156 ---KKDNFWEMGDTGPCGPCSEIFYDRGPEYGGGPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLE 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 241 RVSAVLQHVHSNYEIDLFQNLLAAAAKAIGC----SNDGQASLKVVADHIRSCGFLIADGVLPSNEGRGYVLRRIIRRAC 316
Cdd:COG0013 233 RIAAVLQGVHSNYETDLFRPLIEAAAELTGVkygaDEEDDVSLRVIADHIRAVAFLIADGVLPSNEGRGYVLRRILRRAV 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 317 RHGNKLGAKGSFFYQIVAALAAEMGEAFPELKSQQAHIERVLKAEEEQFAKTLEQGLRILEQDLAQLK---GDVVPGDVV 393
Cdd:COG0013 313 RHGRLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKLKaagGKVLSGEDA 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 394 FKLYDTYGFPMDLTADIARERELTIDEAGFEREMDAQRERARSASAFGMD------YNSLVKVDSATEFLGYDATEGQGK 467
Cdd:COG0013 393 FKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDaavdgvWRELLEEGGPTEFVGYDTLEAEAK 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 468 IIALYKDGQSVDQLGEGEEGVVVLDRTPFYAESGGQVGDTGFLQAGAARFDVRDTTK-TGGAFLHHGVVTSGALVIGSPV 546
Cdd:COG0013 473 VLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEGDGGVFEVTDTQKpPGGLIVHIGKVEEGELKVGDTV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 547 EAKVDADVQHATSLNHSATHLLHEALRQVLGEHVQQKGSLVDSQRLRFDFSHFEAVKPEQIKQLEDIVNREIRKNTPVET 626
Cdd:COG0013 553 TAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVET 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 627 ELTDIETAKAKGAMALFGEKYGDTVRVLSMgGDFSVELCGGIHAKRTGDISLFKIISEGGVASGVRRIEAVTGAAALAYL 706
Cdd:COG0013 633 REMPLDEAKALGAMALFGEKYGDEVRVVSI-GDFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYL 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 707 NAAEEQVKEAAQLVKGNRDNLIDKLSAVLERNRQLEKQLEQLQAKAASAAGDDLSNAAVEVKGAKVLAARLDGQDGKALL 786
Cdd:COG0013 712 REQEALLKELAELLKAPPEELPERVEALLEELKELEKELEQLKAKLASAAADDLLAQAEEIGGVKVLAARVEGVDAKDLR 791
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499257632 787 ALVDQLKNKLGHAVILLGSEHEGKVVLVAGVTKDLSSQ-LKAGDLMKQAAAAVGGKGGGRPDMAQGGGVDV 856
Cdd:COG0013 792 DLADDLKDKLGSGVVVLASVADGKVSLVAGVTKDLVKKgLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDP 862
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
5-853 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 1084.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 5 EIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLGAEKRAYTRAVSSQKCVRAggkhNDLENVGYTAR 84
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSNRLTNAQPCIRL----NDLENVGRTAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 85 HHTFFEMLGNFSFGDYFKRDAITFAWTFLTSEqwLNLPKEKLWVTVYATDDEAYDIWtkevgvpaERMVRIGDNKGAPYA 164
Cdd:TIGR00344 77 HHTLFEMLGNFSFGDYFKEEAIAFAWELLTEV--LGLDKERLYVTVYEDDEEAYKIW--------EKIGIPADRIIKCDA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 165 SDNFWTMGDtGPCGPCTEIFYDHgpdiWGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLERVSA 244
Cdd:TIGR00344 147 KDNFWDMGD-GPCGPCTEIYYDF----VGGKPGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVA 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 245 VLQHVHSNYEIDLFQNLLAAAAKAIGCS-------------NDGQASLKVVADHIRSCGFLIADGVLPSNEGRGYVLRRI 311
Cdd:TIGR00344 222 VLQGVPTNYDTDIFLPLIEKIEEITGVKydsnnagimdekrVEDLRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRL 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 312 IRRACRHGNKLGAKGSFFYQIVAALAAEMGEAFPELKSQQAHIERVLKAEEEQFAKTLEQGLRILEQDLAQLKGDVVPGD 391
Cdd:TIGR00344 302 IRRALRHGKKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGKKELDGE 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 392 VVFKLYDTYGFPMDLTADIARERELTIDEAGFEREMDAQRERARSASAFGMDYNSLVKVDSATEFLGYDATEGQGKIIAL 471
Cdd:TIGR00344 382 DAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQEQEIALVNVYPATEFLGYDDLEFEAKVIGL 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 472 YKDGQSVDQLGEGEEGVVVLDRTPFYAESGGQVGDTGFLQAGAARFDVRDTTKTGGAFLHHGVVTSGALVIGSPVEAKVD 551
Cdd:TIGR00344 462 FDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIANDGKFRVVDVQKPNGVVFHFGEVEGGSLKVGDKVIAVID 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 552 ADVQHATSLNHSATHLLHEALRQVLGEHVQQKGSLVDSQRLRFDFSHFEAVKPEQIKQLEDIVNREIRKNTPVETELTDI 631
Cdd:TIGR00344 542 EKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLANEQILANIPIKVIFMDL 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 632 ETAKAKGAMALFGEKY--GDTVRVLSMgGDFSVELCGGIHAKRTGDISLFKIISEGGVASGVRRIEAVTGAAALAYLNAA 709
Cdd:TIGR00344 622 DEAKRKGAFALFGEKYvpGEKVRVVSV-GDFSVELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYLNEQ 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 710 EEQVKEAAQLVKGNRDNLIDKLSAVLERNRQLEKQLEQLQAKAASAAGDDLSNAAVEVKGAKVLAARLDGQDGKALLALV 789
Cdd:TIGR00344 701 EDKLKELADILKVTPNELPKKVERFFEEWKALQKELESLKLKIADQKIDELKDKAETINGVKVLVEVVDAKDMKSLKTMA 780
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499257632 790 DQLKNKLGHAVILLGSEHEGKVVLVAGVTKDL-SSQLKAGDLMKQAAAAVGGKGGGRPDMAQGGG 853
Cdd:TIGR00344 781 DRLKSKLGSAIYVLASFAEGKVKLVCGVSNDVlTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
1-856 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 936.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 1 MKSAEIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLG-----AEKRAYTRAVSSQKCVRAGGKHND 75
Cdd:PLN02900 11 WPGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGtadpnTPLRKLPRATNTQKCIRAGGKHND 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 76 LENVGYTARHHTFFEMLGNFSFGDYFKRDAITFAWTFLTseQWLNLPKEKLWVTVY------ATDDEAYDIWTKEVgvPA 149
Cdd:PLN02900 91 LDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLT--KVYGLPADRLYATYFggdekqAPDDEARAIWLDYL--PE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 150 ERMVRIGdnkgapyASDNFWTMGDTGPCGPCTEIFYDHGPDiwGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLP 229
Cdd:PLN02900 167 ERVLPFG-------CKDNFWEMGDTGPCGPCSEIHYDRIGE--RDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 230 APSVDTGMGLERVSAVLQHVHSNYEIDLFQNLLAAAAKAIGCSN----DGQA-------SLKVVADHIRSCGFLIADGVL 298
Cdd:PLN02900 238 AKHVDTGMGLERLASILQNKPSNYDTDLFMPIFDAIQEATGARPyagkVGAEdddrvdmAYRVVADHIRTLSFAIADGVV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 299 PSNEGRGYVLRRIIRRACRHGN-KLGAKGSFFYQIVAALAAEMGEAFPELKSQQAHIERVLKAEEEQFAKTLEQGLRILE 377
Cdd:PLN02900 318 PSNEGRGYVLRRLLRRAVRYGRlLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFK 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 378 QDLAQLK---GDVVPGDVVFKLYDTYGFPMDLTADIARERELTIDEAGFEREMDAQRERARSASAFG------MDYNS-- 446
Cdd:PLN02900 398 KALAAAKangGPVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAHLKAgggaieLAAEAts 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 447 -LVK--VDSATEFLGYDATEGQGKII-ALYKDGQSVDQLGEGEEGVVVLDRTPFYAESGGQVGDTGFLQ-AGAARFDVRD 521
Cdd:PLN02900 478 wLQKqgVAATDDFLKYDWLSDHEAVVkAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEgSGGAVVEVSD 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 522 TTKTGGAFLHHGVVTSGALVIGSPVEAKVDADVQHATSLNHSATHLLHEALRQVLGEHVQQKGSLVDSQRLRFDFSHFEA 601
Cdd:PLN02900 558 VQKAGGFVLHIGTVTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDFSHGKP 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 602 VKPEQIKQLEDIVNREIRKNTPVETELTDIETAKA-KGAMALFGEKYGDTVRVLSMGGDFSVELCGGIHAKRTGDISLFK 680
Cdd:PLN02900 638 MTPEELREVESLVNEWIGDALPVEAKEMPLADAKRiNGLRAVFGEKYPDPVRVVSVGGVYSMELCGGTHVSNTAEAEAFK 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 681 IISEGGVASGVRRIEAVTGAAALAYLNAAEEQVKE------------------------AAQLVKGNRDNLIDKLSAVLE 736
Cdd:PLN02900 718 LLSEEGIAKGIRRITAVTGGAAVEAINAADSLEREldsalkvegsdlekkvaslksrvdAAVIPAAKKEEIRARVSALQK 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 737 RNRQLEKQLEQLQAKAASAAGDDLSNAAVEVkGAKVLAARLD-GQDGKALLALVDQLKNKLGH-AVILLGS-EHEGKVVL 813
Cdd:PLN02900 798 ELRAAQKEAAALRAKLAVAKATELASKALSA-GKSVLVARLDvGVDAAALKEAAEKVIAKLGDpAAVVLSSdEEKGKVSL 876
|
890 900 910 920
....*....|....*....|....*....|....*....|....
gi 499257632 814 VAGVTKDL-SSQLKAGDLMKQAAAAVGGKGGGRPDMAQGGGVDV 856
Cdd:PLN02900 877 VAAVPPGVvKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDA 920
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
5-553 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 810.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 5 EIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLGAE-KRAYTRAVSSQKCVRAGgkhnDLENVGYTA 83
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVaKPPYNRATNSQKCIRAG----DLENVGRTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 84 RHHTFFEMLGNFSFGDYFKRDAITFAWTFLTseQWLNLPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGDNkgapy 163
Cdd:pfam01411 77 RHHTFFEMLGNFSFGDYFKEEAIEYAWELLT--KELGLPPERLYVTVFEWDDEAGPIWEKIVGGPEERILRFGDK----- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 164 asDNFWTMGDTGPCGPCTEIFYDHGPDIWGGPPGSPEE-DGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLERV 242
Cdd:pfam01411 150 --DNFWEMGDTGPCGPCSEIDYDRGEEIGGWDSGGTPTaDDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLERL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 243 SAVLQHVHSNYEIDLFQNLLAAAAKAIGC---SNDG-QASLKVVADHIRSCGFLIADGVLPSNEGRGYVLRRIIRRACRH 318
Cdd:pfam01411 228 VAVLQDVRSNYDTDVFIPVIELIEEISGAryyTVDEtDEAYRVIADHTRALTFALADGVVPSNEGRGYVLRRILRRAVRH 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 319 GNKLGAKGSFFYQIVAALAAEMGEAFPELKSQQAHIERVLKAEEEQFAKTLEQGLRILEQDLAQLK--GDVVPGDVVFKL 396
Cdd:pfam01411 308 AKKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKkgKKTLPGEDAFKL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 397 YDTYGFPMDLTADIARERELTIDEAGFEREMDAQRERARSASAFG---MDYNSLVKVDSATEFLGYDATEGQGKIIALYK 473
Cdd:pfam01411 388 YDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKgekLDVSALKELPATTEFLGYDDLESEAKILALPK 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 474 DGQSVDQLGEGEEGVVVLDRTPFYAESGGQVGDTGFLQAGAARFDVRDTTKTGGAFLHHGVVTSGALVIGSPVEAKVDAD 553
Cdd:pfam01411 468 DGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIGDGGEFRVTDVQKYGGVVVHKGKLESGKLKVGDKVIAVIDED 547
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
3-249 |
1.48e-130 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 390.18 E-value: 1.48e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 3 SAEIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLGAEKRAYTRAVSSQKCVRAGGKHNdlenVGYT 82
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPANRLVNSQKCIRAGDIDN----VGKT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 83 ARHHTFFEMLGNFSFGDYFKRDAITFAWTFLTSEQWlnLPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGdnkgap 162
Cdd:cd00673 77 GRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLG--LPKDRLYVSVFEGDDEEEAIWWWKIGLPGIRIERIG------ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 163 yASDNFWTMGDTGPCGPCTEIFYDHGPDIWGGPpgSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLERV 242
Cdd:cd00673 149 -FKDNFWEMGGNGPCGPCSEIFYDRGEERDAAS--LPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERL 225
|
....*..
gi 499257632 243 SAVLQHV 249
Cdd:cd00673 226 VWVLQGV 232
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
651-694 |
8.52e-16 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 71.64 E-value: 8.52e-16
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 499257632 651 VRVLSMGgDFSVELCGGIHAKRTGDISLFKIISEGGVASGVRRI 694
Cdd:smart00863 1 VRVVSIG-DFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
1-856 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1560.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 1 MKSAEIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLGAEKRAYTRAVSSQKCVRAGGKHNDLENVG 80
Cdd:COG0013 2 MTSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPYPRATTSQKCVRTGGKHNDLENVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 81 YTARHHTFFEMLGNFSFGDYFKRDAITFAWTFLTseQWLNLPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGdnkg 160
Cdd:COG0013 82 YTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLT--EVLGLPKERLWVTVYEDDDEAYDIWKKEIGVPEERIIRLG---- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 161 apyASDNFWTMGDTGPCGPCTEIFYDHGPDIWGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLE 240
Cdd:COG0013 156 ---KKDNFWEMGDTGPCGPCSEIFYDRGPEYGGGPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDTGMGLE 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 241 RVSAVLQHVHSNYEIDLFQNLLAAAAKAIGC----SNDGQASLKVVADHIRSCGFLIADGVLPSNEGRGYVLRRIIRRAC 316
Cdd:COG0013 233 RIAAVLQGVHSNYETDLFRPLIEAAAELTGVkygaDEEDDVSLRVIADHIRAVAFLIADGVLPSNEGRGYVLRRILRRAV 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 317 RHGNKLGAKGSFFYQIVAALAAEMGEAFPELKSQQAHIERVLKAEEEQFAKTLEQGLRILEQDLAQLK---GDVVPGDVV 393
Cdd:COG0013 313 RHGRLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKLKaagGKVLSGEDA 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 394 FKLYDTYGFPMDLTADIARERELTIDEAGFEREMDAQRERARSASAFGMD------YNSLVKVDSATEFLGYDATEGQGK 467
Cdd:COG0013 393 FKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDaavdgvWRELLEEGGPTEFVGYDTLEAEAK 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 468 IIALYKDGQSVDQLGEGEEGVVVLDRTPFYAESGGQVGDTGFLQAGAARFDVRDTTK-TGGAFLHHGVVTSGALVIGSPV 546
Cdd:COG0013 473 VLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTIEGDGGVFEVTDTQKpPGGLIVHIGKVEEGELKVGDTV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 547 EAKVDADVQHATSLNHSATHLLHEALRQVLGEHVQQKGSLVDSQRLRFDFSHFEAVKPEQIKQLEDIVNREIRKNTPVET 626
Cdd:COG0013 553 TAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVET 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 627 ELTDIETAKAKGAMALFGEKYGDTVRVLSMgGDFSVELCGGIHAKRTGDISLFKIISEGGVASGVRRIEAVTGAAALAYL 706
Cdd:COG0013 633 REMPLDEAKALGAMALFGEKYGDEVRVVSI-GDFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYL 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 707 NAAEEQVKEAAQLVKGNRDNLIDKLSAVLERNRQLEKQLEQLQAKAASAAGDDLSNAAVEVKGAKVLAARLDGQDGKALL 786
Cdd:COG0013 712 REQEALLKELAELLKAPPEELPERVEALLEELKELEKELEQLKAKLASAAADDLLAQAEEIGGVKVLAARVEGVDAKDLR 791
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499257632 787 ALVDQLKNKLGHAVILLGSEHEGKVVLVAGVTKDLSSQ-LKAGDLMKQAAAAVGGKGGGRPDMAQGGGVDV 856
Cdd:COG0013 792 DLADDLKDKLGSGVVVLASVADGKVSLVAGVTKDLVKKgLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDP 862
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
5-853 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 1084.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 5 EIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLGAEKRAYTRAVSSQKCVRAggkhNDLENVGYTAR 84
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSNRLTNAQPCIRL----NDLENVGRTAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 85 HHTFFEMLGNFSFGDYFKRDAITFAWTFLTSEqwLNLPKEKLWVTVYATDDEAYDIWtkevgvpaERMVRIGDNKGAPYA 164
Cdd:TIGR00344 77 HHTLFEMLGNFSFGDYFKEEAIAFAWELLTEV--LGLDKERLYVTVYEDDEEAYKIW--------EKIGIPADRIIKCDA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 165 SDNFWTMGDtGPCGPCTEIFYDHgpdiWGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLERVSA 244
Cdd:TIGR00344 147 KDNFWDMGD-GPCGPCTEIYYDF----VGGKPGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFVA 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 245 VLQHVHSNYEIDLFQNLLAAAAKAIGCS-------------NDGQASLKVVADHIRSCGFLIADGVLPSNEGRGYVLRRI 311
Cdd:TIGR00344 222 VLQGVPTNYDTDIFLPLIEKIEEITGVKydsnnagimdekrVEDLRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRL 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 312 IRRACRHGNKLGAKGSFFYQIVAALAAEMGEAFPELKSQQAHIERVLKAEEEQFAKTLEQGLRILEQDLAQLKGDVVPGD 391
Cdd:TIGR00344 302 IRRALRHGKKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGKKELDGE 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 392 VVFKLYDTYGFPMDLTADIARERELTIDEAGFEREMDAQRERARSASAFGMDYNSLVKVDSATEFLGYDATEGQGKIIAL 471
Cdd:TIGR00344 382 DAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQFQEQEIALVNVYPATEFLGYDDLEFEAKVIGL 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 472 YKDGQSVDQLGEGEEGVVVLDRTPFYAESGGQVGDTGFLQAGAARFDVRDTTKTGGAFLHHGVVTSGALVIGSPVEAKVD 551
Cdd:TIGR00344 462 FDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIANDGKFRVVDVQKPNGVVFHFGEVEGGSLKVGDKVIAVID 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 552 ADVQHATSLNHSATHLLHEALRQVLGEHVQQKGSLVDSQRLRFDFSHFEAVKPEQIKQLEDIVNREIRKNTPVETELTDI 631
Cdd:TIGR00344 542 EKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLANEQILANIPIKVIFMDL 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 632 ETAKAKGAMALFGEKY--GDTVRVLSMgGDFSVELCGGIHAKRTGDISLFKIISEGGVASGVRRIEAVTGAAALAYLNAA 709
Cdd:TIGR00344 622 DEAKRKGAFALFGEKYvpGEKVRVVSV-GDFSVELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYLNEQ 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 710 EEQVKEAAQLVKGNRDNLIDKLSAVLERNRQLEKQLEQLQAKAASAAGDDLSNAAVEVKGAKVLAARLDGQDGKALLALV 789
Cdd:TIGR00344 701 EDKLKELADILKVTPNELPKKVERFFEEWKALQKELESLKLKIADQKIDELKDKAETINGVKVLVEVVDAKDMKSLKTMA 780
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499257632 790 DQLKNKLGHAVILLGSEHEGKVVLVAGVTKDL-SSQLKAGDLMKQAAAAVGGKGGGRPDMAQGGG 853
Cdd:TIGR00344 781 DRLKSKLGSAIYVLASFAEGKVKLVCGVSNDVlTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
1-856 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 936.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 1 MKSAEIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLG-----AEKRAYTRAVSSQKCVRAGGKHND 75
Cdd:PLN02900 11 WPGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGtadpnTPLRKLPRATNTQKCIRAGGKHND 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 76 LENVGYTARHHTFFEMLGNFSFGDYFKRDAITFAWTFLTseQWLNLPKEKLWVTVY------ATDDEAYDIWTKEVgvPA 149
Cdd:PLN02900 91 LDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLT--KVYGLPADRLYATYFggdekqAPDDEARAIWLDYL--PE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 150 ERMVRIGdnkgapyASDNFWTMGDTGPCGPCTEIFYDHGPDiwGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLP 229
Cdd:PLN02900 167 ERVLPFG-------CKDNFWEMGDTGPCGPCSEIHYDRIGE--RDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 230 APSVDTGMGLERVSAVLQHVHSNYEIDLFQNLLAAAAKAIGCSN----DGQA-------SLKVVADHIRSCGFLIADGVL 298
Cdd:PLN02900 238 AKHVDTGMGLERLASILQNKPSNYDTDLFMPIFDAIQEATGARPyagkVGAEdddrvdmAYRVVADHIRTLSFAIADGVV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 299 PSNEGRGYVLRRIIRRACRHGN-KLGAKGSFFYQIVAALAAEMGEAFPELKSQQAHIERVLKAEEEQFAKTLEQGLRILE 377
Cdd:PLN02900 318 PSNEGRGYVLRRLLRRAVRYGRlLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFK 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 378 QDLAQLK---GDVVPGDVVFKLYDTYGFPMDLTADIARERELTIDEAGFEREMDAQRERARSASAFG------MDYNS-- 446
Cdd:PLN02900 398 KALAAAKangGPVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAHLKAgggaieLAAEAts 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 447 -LVK--VDSATEFLGYDATEGQGKII-ALYKDGQSVDQLGEGEEGVVVLDRTPFYAESGGQVGDTGFLQ-AGAARFDVRD 521
Cdd:PLN02900 478 wLQKqgVAATDDFLKYDWLSDHEAVVkAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEgSGGAVVEVSD 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 522 TTKTGGAFLHHGVVTSGALVIGSPVEAKVDADVQHATSLNHSATHLLHEALRQVLGEHVQQKGSLVDSQRLRFDFSHFEA 601
Cdd:PLN02900 558 VQKAGGFVLHIGTVTEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDFSHGKP 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 602 VKPEQIKQLEDIVNREIRKNTPVETELTDIETAKA-KGAMALFGEKYGDTVRVLSMGGDFSVELCGGIHAKRTGDISLFK 680
Cdd:PLN02900 638 MTPEELREVESLVNEWIGDALPVEAKEMPLADAKRiNGLRAVFGEKYPDPVRVVSVGGVYSMELCGGTHVSNTAEAEAFK 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 681 IISEGGVASGVRRIEAVTGAAALAYLNAAEEQVKE------------------------AAQLVKGNRDNLIDKLSAVLE 736
Cdd:PLN02900 718 LLSEEGIAKGIRRITAVTGGAAVEAINAADSLEREldsalkvegsdlekkvaslksrvdAAVIPAAKKEEIRARVSALQK 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 737 RNRQLEKQLEQLQAKAASAAGDDLSNAAVEVkGAKVLAARLD-GQDGKALLALVDQLKNKLGH-AVILLGS-EHEGKVVL 813
Cdd:PLN02900 798 ELRAAQKEAAALRAKLAVAKATELASKALSA-GKSVLVARLDvGVDAAALKEAAEKVIAKLGDpAAVVLSSdEEKGKVSL 876
|
890 900 910 920
....*....|....*....|....*....|....*....|....
gi 499257632 814 VAGVTKDL-SSQLKAGDLMKQAAAAVGGKGGGRPDMAQGGGVDV 856
Cdd:PLN02900 877 VAAVPPGVvKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDA 920
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
5-553 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 810.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 5 EIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLGAE-KRAYTRAVSSQKCVRAGgkhnDLENVGYTA 83
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVaKPPYNRATNSQKCIRAG----DLENVGRTG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 84 RHHTFFEMLGNFSFGDYFKRDAITFAWTFLTseQWLNLPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGDNkgapy 163
Cdd:pfam01411 77 RHHTFFEMLGNFSFGDYFKEEAIEYAWELLT--KELGLPPERLYVTVFEWDDEAGPIWEKIVGGPEERILRFGDK----- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 164 asDNFWTMGDTGPCGPCTEIFYDHGPDIWGGPPGSPEE-DGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLERV 242
Cdd:pfam01411 150 --DNFWEMGDTGPCGPCSEIDYDRGEEIGGWDSGGTPTaDDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGLERL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 243 SAVLQHVHSNYEIDLFQNLLAAAAKAIGC---SNDG-QASLKVVADHIRSCGFLIADGVLPSNEGRGYVLRRIIRRACRH 318
Cdd:pfam01411 228 VAVLQDVRSNYDTDVFIPVIELIEEISGAryyTVDEtDEAYRVIADHTRALTFALADGVVPSNEGRGYVLRRILRRAVRH 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 319 GNKLGAKGSFFYQIVAALAAEMGEAFPELKSQQAHIERVLKAEEEQFAKTLEQGLRILEQDLAQLK--GDVVPGDVVFKL 396
Cdd:pfam01411 308 AKKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKkgKKTLPGEDAFKL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 397 YDTYGFPMDLTADIARERELTIDEAGFEREMDAQRERARSASAFG---MDYNSLVKVDSATEFLGYDATEGQGKIIALYK 473
Cdd:pfam01411 388 YDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKgekLDVSALKELPATTEFLGYDDLESEAKILALPK 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 474 DGQSVDQLGEGEEGVVVLDRTPFYAESGGQVGDTGFLQAGAARFDVRDTTKTGGAFLHHGVVTSGALVIGSPVEAKVDAD 553
Cdd:pfam01411 468 DGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTGYIIGDGGEFRVTDVQKYGGVVVHKGKLESGKLKVGDKVIAVIDED 547
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
1-697 |
0e+00 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 543.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 1 MKSAEIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLGAEKRAYTRAVSSQKCVRAGgkhnDLENVG 80
Cdd:PRK01584 1 MTLDELRKKYIDFFKSKGHVEIAGKSLIPENDPTVLFTTAGMHPLVPYLLGEPHPSGTRLVDVQKCLRTG----DIDEVG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 81 yTARHHTFFEMLGNFSFGDYFKRDAITFAWTFLTSEQWLNLPKEKLWVTVYATDD------EAYDIWtKEVGVPAERMVR 154
Cdd:PRK01584 77 -DLSHLTFFEMLGNWSLGAYFKEESIKYSFEFLTSPDYLNIPKDKLYVTVFEGDEeiprdeETASVW-ESLGIPKDRIFY 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 155 IGdnkgapyASDNFW-TMGDTGPCGPCTEIFYDHGPDIWGGPPGsPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSV 233
Cdd:PRK01584 155 LS-------REHNWWgPVGETGPCGPDTEIFVDTGKPKCSVNCR-PTCSCGKYFEIWNNVFMQYNKDEDGNYEELKRKCV 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 234 DTGMGLERVSAVLQHVHSNYEIDLFQNLLAA----AAKAIGCSNDGQASLKVVADHIRSCGFLIAD--GVLPSNEGRGYV 307
Cdd:PRK01584 227 DTGMGIERTIAFLQGKSSVYDTEAFTPIIKRiekiSGKIYGQNEEDDRSIRIIADHIRAACFILGDpfVVLPSNVGQGYV 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 308 LRRIIRRACRHGNKLGAKGSFFYQIVAALAAEMGEAFPELKSQQAHIERVLKAEEEQFAKTLEQGLRILEQDLAQLKGD- 386
Cdd:PRK01584 307 LRRLIRRSIRHAKKLGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEFIKLIPNLGSSk 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 387 VVPGDVVFKLYDTYGFPMDLTADIARERELTIDEAGFEREMDAQRERARsasafgmdynslvkvdsateflgydategqg 466
Cdd:PRK01584 387 IIPGDIAFKLYDTYGFPYEITEELASEYGFTVDREGFDEHFKKHQKVSK------------------------------- 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 467 kiialykdgqsvdqlgegeegvvvldrtpfyaeSGGQvgdtgflqagaarfdvrdttktggaflhhgVVTSGALvigspv 546
Cdd:PRK01584 436 ---------------------------------KGAD------------------------------KVFKGGL------ 446
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 547 eakvdADVQHATSLNHSATHLLHEALRQVLGEHVQQKGSLVDSQRLRFDFSHFEAVKPEQIKQLEDIVNREIRKNTPVET 626
Cdd:PRK01584 447 -----ADHSYETTKLHTATHLLHKALRLVLGDHVRQKGSNITAERLRFDFSHPEKMTDDEIKKVEDIVNLQIKNDLSVKK 521
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499257632 627 ELTDIETAKAKGAMALFGEKYGDTVRVLSMGGdFSVELCGGIHAKRTGDISLFKIISEGGVASGVRRIEAV 697
Cdd:PRK01584 522 EVMSLEEAREKGAMALFGEKYEDIVKVYEIDG-FSKEVCGGPHVENTGELGTFKIQKEQSSSSGVRRIRAI 591
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
3-249 |
1.48e-130 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 390.18 E-value: 1.48e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 3 SAEIREAFLRFFEEQGHTRVASSSLIPNNDPTLLFTNAGMNQFKDCFLGAEKRAYTRAVSSQKCVRAGGKHNdlenVGYT 82
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPANRLVNSQKCIRAGDIDN----VGKT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 83 ARHHTFFEMLGNFSFGDYFKRDAITFAWTFLTSEQWlnLPKEKLWVTVYATDDEAYDIWTKEVGVPAERMVRIGdnkgap 162
Cdd:cd00673 77 GRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLG--LPKDRLYVSVFEGDDEEEAIWWWKIGLPGIRIERIG------ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 163 yASDNFWTMGDTGPCGPCTEIFYDHGPDIWGGPpgSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLERV 242
Cdd:cd00673 149 -FKDNFWEMGGNGPCGPCSEIFYDRGEERDAAS--LPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLERL 225
|
....*..
gi 499257632 243 SAVLQHV 249
Cdd:cd00673 226 VWVLQGV 232
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
454-695 |
2.21e-28 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 114.13 E-value: 2.21e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 454 TEFLGYD---ATEGQGKIIALykdgqsvdqlgeGEEGVVVLDRTPFYAESGGQVGDTGFLQAGAARFDVRDTTKTGGAFL 530
Cdd:COG2872 2 TELLYLEdsyLKEFEATVTAV------------TEEGGVVLDRTAFYPTGGGQPGDTGTLVWDGKEIRVVDVRKEDGEIV 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 531 HHgVVTSGALVIGSPVEAKVDADVQHATSLNHSATHLLHEALRQVLGEHVqqKGSLVDSQRLRFDFsHFEAVKPEQIKQL 610
Cdd:COG2872 70 HV-LEGAPLPEVGDEVTGEIDWERRYRHMRLHTALHLLSAVVYREYGAPV--TGGQIGEDRARIDF-DLPEFDEEDLEEI 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 611 EDIVNREIRKNTPVETE-LTDIETAKAKG---AMALFGEKYGDTVRVLSMGGdFSVELCGGIHAKRT---GDISLFKIIS 683
Cdd:COG2872 146 EAEANELIAADLPVRIYwITREELEAIPGlvrTMSVLPPPGVGRVRIVEIGG-VDLQPCGGTHVANTgeiGRIKITKIEK 224
|
250
....*....|..
gi 499257632 684 EGgvaSGVRRIE 695
Cdd:COG2872 225 KG---KGNRRVY 233
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
651-694 |
8.52e-16 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 71.64 E-value: 8.52e-16
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 499257632 651 VRVLSMGgDFSVELCGGIHAKRTGDISLFKIISEGGVASGVRRI 694
Cdd:smart00863 1 VRVVSIG-DFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
651-694 |
3.67e-14 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 67.08 E-value: 3.67e-14
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 499257632 651 VRVLSMGgDFSVELCGGIHAKRTGDISLFKIISEGGVASGVRRI 694
Cdd:pfam07973 1 VRVVSIG-DFDVDLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| DHHA1 |
pfam02272 |
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ... |
731-855 |
1.85e-12 |
|
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, suggesting that this domain may have an RNA binding function. The domain is about 60 residues long and contains a conserved GG motif.
Pssm-ID: 396724 [Multi-domain] Cd Length: 139 Bit Score: 65.54 E-value: 1.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 731 LSAVLERNRQLEKQLEQLQAKAASAAGDDLSNAAVEVKGAKVLAARLDGQ-DGKALLALVDQLKNKLGHAVI-LLGSEHE 808
Cdd:pfam02272 1 LESLNEELKELEKELEELKEALALLKAKELLEKAEEINGVKVLVAEVGEGwDAGALGIAADRLKKKLGDPVIvLVAKEDG 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 499257632 809 GKVVLVAGVTKDlsSQLKAGDLMKQAAAAVGGKGGGRpDMAQGGGVD 855
Cdd:pfam02272 81 DKVKVSARSSKD--KGVDAGELLKEVAAILGGGGGGH-DLAAGAGID 124
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
488-681 |
1.56e-11 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 64.72 E-value: 1.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 488 VVVLDRTPFYAESGGQVGDTGFLQA--GAARFDVRDTTKTGGAFLHHGVVTSGALVIGSPVEA------KVDADVQHATS 559
Cdd:PLN02961 4 ALVLDRTIFHPQGGGQPSDTGRIVIsgGDTKFSVQDVRRKDGVVYHYGVFEGSNPESASPFEAgdevtvTVDESRRKLHS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 560 LNHSATHLLHEALRQVlgehvqQKGSLVDSQRLRF-DFSHFE---AVKPEQI----KQLEDIVNREIRKNTPVETELTDI 631
Cdd:PLN02961 84 RLHSAGHLLDVCMARV------GLGPLEPGKGYHFpDGPFVEykgKIPQGELdskqDELEAEANELIAEGGKVSAAVLPY 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 499257632 632 ETAKA--KGAMALFGEKyGDTVRVLSMgGDFSVELCGGIHAKRTGDISLFKI 681
Cdd:PLN02961 158 DEAAElcGGSLPDYIAK-DSTPRIVKI-GDSPGCPCGGTHVADVSEITSVKV 207
|
|
| Seryl_tRNA_N |
pfam02403 |
Seryl-tRNA synthetase N-terminal domain; This domain is found associated with the Pfam tRNA ... |
711-796 |
1.11e-03 |
|
Seryl-tRNA synthetase N-terminal domain; This domain is found associated with the Pfam tRNA synthetase class II domain (pfam00587) and represents the N-terminal domain of seryl-tRNA synthetase.
Pssm-ID: 426757 [Multi-domain] Cd Length: 108 Bit Score: 39.49 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499257632 711 EQVKEAaQLVKGNRDNLIDKLSAVLERNRQLEKQLEQLQAKaasaagddlSNAAvevkGAKVLAARLDGQDGKALLALVD 790
Cdd:pfam02403 12 EAVKES-LKKRGVDVLDVDELLELDEKRRELQVELEELQAE---------RNEL----SKEIGQAKKKKEDADALIAEVK 77
|
....*.
gi 499257632 791 QLKNKL 796
Cdd:pfam02403 78 ELKDEL 83
|
|
| |
