|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-1038 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1438.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFES 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 81 STSSSGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTSTDGSMDAIGLGDYLSR 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLFATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGAQPNPITQQVTAPVVIKGQL 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 241 SSPEEFGAIVLRANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPEG 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 321 LEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 401 AIGILVDDAIIVVENVERIMSEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILF 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 481 SALLALSLTPALCASFLKQVPKGHHHA-KRGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLP 559
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPIEKGEHHEkKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 560 SSFLPDEDQGFVIVMMQLPSEATANRTTEVIEQ-TETIFGQEKA-VDTIVAINGFSFFGSGQNAGLAFVTLKDWSERDAD 637
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQvTKYLLAKEKAnVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 638 -NSAQSIAGRATMAMSQIKDAISFALSPPAIQGLGTTGGFSFRLQDRAGLGQAALAEARDQLLDLASQSKVLTGVRFEGM 716
Cdd:TIGR00915 641 eNSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPALTRVRPNGL 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 717 PDAAQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPL 796
Cdd:TIGR00915 721 EDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVPF 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 797 SAFADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAELPAGFGYEWTGQSLQEIQSGSQAPLLIALSC 876
Cdd:TIGR00915 801 SAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALSL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 877 LLVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLID 956
Cdd:TIGR00915 881 LVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVE 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 957 STLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAIFFVPVFFVFVMKIFERGRAAPEA 1036
Cdd:TIGR00915 961 AALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEKEM 1040
|
..
gi 499271021 1037 AK 1038
Cdd:TIGR00915 1041 SV 1042
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
1-1032 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 1262.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFES 80
Cdd:PRK09577 1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 81 STSSSGSVsIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTSTDGSMDAIGLGDYLSR 160
Cdd:PRK09577 81 TSSAGQAS-LSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLFATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGAQPNPITQQVTAPVVIKGQL 240
Cdd:PRK09577 160 NVLQALRRVEGVGKVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 241 SSPEEFGAIVLRANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPEG 320
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 321 LEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVL 400
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 401 AIGILVDDAIIVVENVERIMSEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILF 480
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 481 SALLALSLTPALCASFLKQVpKGHHHAKRGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLPS 560
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPV-DGDHHEKRGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPT 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 561 SFLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGFSFFGSGQNAGLAFVTLKDWSER-DADNS 639
Cdd:PRK09577 559 AFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGEGPNGGMIFVTLKDWKERkAARDH 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 640 AQSIAGRATMAMSQIKDAISFALSPPAIQGLGTTGGFSFRLQDRAGLGQAALAEARDQLLDLASQSKVLTGVRFEGMPDA 719
Cdd:PRK09577 639 VQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDPALTDLMFAGTQDA 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 720 AQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLSAF 799
Cdd:PRK09577 719 PQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVPLAAF 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 800 ADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAELPAGFGYEWTGQSLQEIQSGSQAPLLIALSCLLV 879
Cdd:PRK09577 799 ATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFEERLSGAQAPMLFALSVLVV 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 880 FLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLIDSTL 959
Cdd:PRK09577 879 FLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQRMSLADAAL 958
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499271021 960 EAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAIFFVPVFFVFVMKIFERGRA 1032
Cdd:PRK09577 959 EAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGRLFDVGPR 1031
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1013 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1180.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFES 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 81 STSSSGSVsIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTSTDgsMDAIGLGDYLSR 160
Cdd:COG0841 83 TSSEGSSS-ITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLF-ATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGaqpnpiTQQVTAPVVIKGQ 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFgGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIG------GGDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 240 LSSPEEFGAIVLRANaDGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPE 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 320 GLEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 400 LAIGILVDDAIIVVENVERIMsEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSIL 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 480 FSALLALSLTPALCASFLKqvpKGHHHAKRGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLP 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLK---PHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLP 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 560 SSFLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGFSFFGSGQNAGLAFVTLKDWSERDAdnS 639
Cdd:COG0841 549 TEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDR--S 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 640 AQSIAGRATMAMSQIKDAISFALSPPAiQGLGTTGGFSFRLQdraGLGQAALAEARDQLLDLASQSKVLTGVRFEGMPDA 719
Cdd:COG0841 627 ADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGK 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 720 AQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLSAF 799
Cdd:COG0841 703 PELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSV 782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 800 ADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAE--LPAGFGYEWTGQSLQEIQSGSQAPLLIALSCL 877
Cdd:COG0841 783 ATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAFLLALL 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 878 LVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLIDS 957
Cdd:COG0841 863 LVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREA 942
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
gi 499271021 958 TLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAI 1013
Cdd:COG0841 943 ILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTL 998
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1013 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1125.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFeS 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYM-S 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 81 STSSSGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTSTDGSMDAIGLGDYLSR 160
Cdd:pfam00873 80 SQSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLF-ATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIgaqpnpITQQVTAPVVIKGQ 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFgGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 240 LSSPEEFGAIVLRaNADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPE 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 320 GLEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 400 LAIGILVDDAIIVVENVERIMSEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSIL 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 480 FSALLALSLTPALCASFLKQVPKGHHHakrGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLP 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKHG---GFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIP 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 560 SSFLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGFSF--FGSGQNAGLAFVTLKDWSERDA- 636
Cdd:pfam00873 550 TEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFsgDNNGPNSGDAFISLKPWKERPGp 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 637 DNSAQSIAGRATMAMSQIKDAISFALSPPAIQGLGTTGGFSFRLQD-RAGLGQAALAEARDQLLDLASQSKVLTGVRFEG 715
Cdd:pfam00873 630 EKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPGLSDVRSDG 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 716 MPDAAQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVP 795
Cdd:pfam00873 710 QEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIP 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 796 LSAFADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAE--LPAGFGYEWTGQSLQEIQSGSQAPLLIA 873
Cdd:pfam00873 790 LSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLPILIA 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 874 LSCLLVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQ-GK 952
Cdd:pfam00873 870 LALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQeGK 949
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499271021 953 SLIDSTLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAI 1013
Cdd:pfam00873 950 SLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTL 1010
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1011 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 687.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 5 FIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFeSSTSS 84
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEM-TSQSS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 85 SGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGV--QVDEAGAGFLlIISLTSTdgSMDAIGLGDYLSRNV 162
Cdd:NF033617 83 LGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVyrKANSADTPIM-YIGLTSE--EMPRGQLTDYAERVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 163 LSEIQRVPGVGRAQLFATER-SMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIgaqpnpITQQVTAPVVIKGQLS 241
Cdd:NF033617 160 APKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAV------RGDSVVSTVRANDQLK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 242 SPEEFGAIVLRANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPEGL 321
Cdd:NF033617 234 TAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 322 EYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVLA 401
Cdd:NF033617 314 KVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 402 IGILVDDAIIVVENVERIMsEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILFS 481
Cdd:NF033617 394 IGLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIIS 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 482 ALLALSLTPALCASFLKQVPKGHHHAKRgffgwFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLPSS 561
Cdd:NF033617 473 GIVALTLTPMMCSRLLKANEKPGRFARA-----VDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKE 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 562 FLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGFSFFgSGQNAGLAFVTLKDWSERDAdnSAQ 641
Cdd:NF033617 548 LAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGN-PGDNTGFGIINLKPWDERDV--SAQ 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 642 SIAGRATMAMSQIKDAISFALSPPAIQGlGTTGGFSFRLQDRAGLGQAALAEARDQLLDLASQSKVLTGVRFEGMPDAAQ 721
Cdd:NF033617 625 EIIDRLRPKLAKVPGMDLFLFPLQDLPG-GAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPE 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 722 VSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLSAFAD 801
Cdd:NF033617 704 LNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAK 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 802 VEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAE-LPAGFGYEWTGQSLQEIQSGSQAPLLIALSCLLVF 880
Cdd:NF033617 784 IEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKElLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIY 863
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 881 LCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKEL-REQGKSLIDSTL 959
Cdd:NF033617 864 LVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELqRHQGLSRREAIY 943
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|..
gi 499271021 960 EAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVL 1011
Cdd:NF033617 944 QAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLF 995
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-1038 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1438.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFES 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 81 STSSSGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTSTDGSMDAIGLGDYLSR 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLFATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGAQPNPITQQVTAPVVIKGQL 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 241 SSPEEFGAIVLRANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPEG 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 321 LEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 401 AIGILVDDAIIVVENVERIMSEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILF 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 481 SALLALSLTPALCASFLKQVPKGHHHA-KRGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLP 559
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPIEKGEHHEkKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 560 SSFLPDEDQGFVIVMMQLPSEATANRTTEVIEQ-TETIFGQEKA-VDTIVAINGFSFFGSGQNAGLAFVTLKDWSERDAD 637
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQvTKYLLAKEKAnVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 638 -NSAQSIAGRATMAMSQIKDAISFALSPPAIQGLGTTGGFSFRLQDRAGLGQAALAEARDQLLDLASQSKVLTGVRFEGM 716
Cdd:TIGR00915 641 eNSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPALTRVRPNGL 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 717 PDAAQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPL 796
Cdd:TIGR00915 721 EDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVPF 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 797 SAFADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAELPAGFGYEWTGQSLQEIQSGSQAPLLIALSC 876
Cdd:TIGR00915 801 SAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALSL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 877 LLVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLID 956
Cdd:TIGR00915 881 LVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVE 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 957 STLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAIFFVPVFFVFVMKIFERGRAAPEA 1036
Cdd:TIGR00915 961 AALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEKEM 1040
|
..
gi 499271021 1037 AK 1038
Cdd:TIGR00915 1041 SV 1042
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
1-1032 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 1262.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFES 80
Cdd:PRK09577 1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 81 STSSSGSVsIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTSTDGSMDAIGLGDYLSR 160
Cdd:PRK09577 81 TSSAGQAS-LSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLFATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGAQPNPITQQVTAPVVIKGQL 240
Cdd:PRK09577 160 NVLQALRRVEGVGKVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 241 SSPEEFGAIVLRANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPEG 320
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 321 LEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVL 400
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 401 AIGILVDDAIIVVENVERIMSEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILF 480
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 481 SALLALSLTPALCASFLKQVpKGHHHAKRGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLPS 560
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPV-DGDHHEKRGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPT 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 561 SFLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGFSFFGSGQNAGLAFVTLKDWSER-DADNS 639
Cdd:PRK09577 559 AFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGEGPNGGMIFVTLKDWKERkAARDH 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 640 AQSIAGRATMAMSQIKDAISFALSPPAIQGLGTTGGFSFRLQDRAGLGQAALAEARDQLLDLASQSKVLTGVRFEGMPDA 719
Cdd:PRK09577 639 VQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDPALTDLMFAGTQDA 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 720 AQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLSAF 799
Cdd:PRK09577 719 PQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVPLAAF 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 800 ADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAELPAGFGYEWTGQSLQEIQSGSQAPLLIALSCLLV 879
Cdd:PRK09577 799 ATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFEERLSGAQAPMLFALSVLVV 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 880 FLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLIDSTL 959
Cdd:PRK09577 879 FLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQRMSLADAAL 958
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499271021 960 EAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAIFFVPVFFVFVMKIFERGRA 1032
Cdd:PRK09577 959 EAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGRLFDVGPR 1031
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
1-1013 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 1227.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFES 80
Cdd:PRK10555 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 81 STSSSGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTSTDGSMDAIGLGDYLSR 160
Cdd:PRK10555 81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLFATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGAQPNPITQQVTAPVVIKGQL 240
Cdd:PRK10555 161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 241 SSPEEFGAIVLRANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPEG 320
Cdd:PRK10555 241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 321 LEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVL 400
Cdd:PRK10555 321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 401 AIGILVDDAIIVVENVERIMSEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILF 480
Cdd:PRK10555 401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 481 SALLALSLTPALCASFLKQVPKGHHHAKRGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLPS 560
Cdd:PRK10555 481 SVLVAMILTPALCATLLKPLKKGEHHGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPT 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 561 SFLPDEDQGFVIVMMQLPSEATANRTTEVIEQTET-IFGQEKA-VDTIVAINGFSFFGSGQNAGLAFVTLKDWSERD-AD 637
Cdd:PRK10555 561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKyYFTHEKDnVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDsKT 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 638 NSAQSIAGRATMAMSQIKDAISFALSPPAIQGLGTTGGFSFRLQDRAGLGQAALAEARDQLLDLASQSKVLTGVRFEGMP 717
Cdd:PRK10555 641 GTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNPELTRVRHNGLD 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 718 DAAQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLS 797
Cdd:PRK10555 721 DSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 798 AFADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAELPAGFGYEWTGQSLQEIQSGSQAPLLIALSCL 877
Cdd:PRK10555 801 AFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLL 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 878 LVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLIDS 957
Cdd:PRK10555 881 VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA 960
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
gi 499271021 958 TLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAI 1013
Cdd:PRK10555 961 TLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAI 1016
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-1013 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 1210.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFES 80
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 81 STSSSGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTSTDGSMDAIGLGDYLSR 160
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLFATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGAQPNPITQQVTAPVVIKGQL 240
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 241 SSPEEFGAIVLRANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPEG 320
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 321 LEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVL 400
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 401 AIGILVDDAIIVVENVERIMSEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILF 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 481 SALLALSLTPALCASFLKQVPKGHH-HAKRGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLP 559
Cdd:PRK15127 481 SVLVALILTPALCATMLKPIAKGDHgEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 560 SSFLPDEDQGFVIVMMQLPSEATANRTTEVIEQ-TETIFGQEKA-VDTIVAINGFSFFGSGQNAGLAFVTLKDWSERD-A 636
Cdd:PRK15127 561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEvTDYYLTKEKNnVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPgE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 637 DNSAQSIAGRATMAMSQIKDAISFALSPPAIQGLGTTGGFSFRLQDRAGLGQAALAEARDQLLDLASQ-SKVLTGVRFEG 715
Cdd:PRK15127 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKhPDMLVGVRPNG 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 716 MPDAAQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVP 795
Cdd:PRK15127 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 796 LSAFADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAELPAGFGYEWTGQSLQEIQSGSQAPLLIALS 875
Cdd:PRK15127 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQERLSGNQAPALYAIS 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 876 CLLVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELRE-QGKSL 954
Cdd:PRK15127 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDkEGKGL 960
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 499271021 955 IDSTLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAI 1013
Cdd:PRK15127 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1013 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1180.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFES 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 81 STSSSGSVsIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTSTDgsMDAIGLGDYLSR 160
Cdd:COG0841 83 TSSEGSSS-ITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLF-ATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGaqpnpiTQQVTAPVVIKGQ 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFgGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIG------GGDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 240 LSSPEEFGAIVLRANaDGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPE 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 320 GLEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 400 LAIGILVDDAIIVVENVERIMsEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSIL 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 480 FSALLALSLTPALCASFLKqvpKGHHHAKRGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLP 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLK---PHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLP 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 560 SSFLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGFSFFGSGQNAGLAFVTLKDWSERDAdnS 639
Cdd:COG0841 549 TEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDR--S 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 640 AQSIAGRATMAMSQIKDAISFALSPPAiQGLGTTGGFSFRLQdraGLGQAALAEARDQLLDLASQSKVLTGVRFEGMPDA 719
Cdd:COG0841 627 ADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGK 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 720 AQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLSAF 799
Cdd:COG0841 703 PELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSV 782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 800 ADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAE--LPAGFGYEWTGQSLQEIQSGSQAPLLIALSCL 877
Cdd:COG0841 783 ATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAFLLALL 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 878 LVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLIDS 957
Cdd:COG0841 863 LVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREA 942
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
gi 499271021 958 TLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAI 1013
Cdd:COG0841 943 ILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTL 998
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1013 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1125.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFeS 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYM-S 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 81 STSSSGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTSTDGSMDAIGLGDYLSR 160
Cdd:pfam00873 80 SQSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLF-ATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIgaqpnpITQQVTAPVVIKGQ 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFgGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 240 LSSPEEFGAIVLRaNADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPE 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 320 GLEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 400 LAIGILVDDAIIVVENVERIMSEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSIL 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 480 FSALLALSLTPALCASFLKQVPKGHHHakrGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLP 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKHG---GFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIP 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 560 SSFLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGFSF--FGSGQNAGLAFVTLKDWSERDA- 636
Cdd:pfam00873 550 TEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFsgDNNGPNSGDAFISLKPWKERPGp 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 637 DNSAQSIAGRATMAMSQIKDAISFALSPPAIQGLGTTGGFSFRLQD-RAGLGQAALAEARDQLLDLASQSKVLTGVRFEG 715
Cdd:pfam00873 630 EKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPGLSDVRSDG 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 716 MPDAAQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVP 795
Cdd:pfam00873 710 QEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIP 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 796 LSAFADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAE--LPAGFGYEWTGQSLQEIQSGSQAPLLIA 873
Cdd:pfam00873 790 LSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLPILIA 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 874 LSCLLVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQ-GK 952
Cdd:pfam00873 870 LALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQeGK 949
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499271021 953 SLIDSTLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAI 1013
Cdd:pfam00873 950 SLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTL 1010
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1011 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 687.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 5 FIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFeSSTSS 84
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEM-TSQSS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 85 SGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGV--QVDEAGAGFLlIISLTSTdgSMDAIGLGDYLSRNV 162
Cdd:NF033617 83 LGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVyrKANSADTPIM-YIGLTSE--EMPRGQLTDYAERVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 163 LSEIQRVPGVGRAQLFATER-SMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIgaqpnpITQQVTAPVVIKGQLS 241
Cdd:NF033617 160 APKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAV------RGDSVVSTVRANDQLK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 242 SPEEFGAIVLRANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPEGL 321
Cdd:NF033617 234 TAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 322 EYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVLA 401
Cdd:NF033617 314 KVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 402 IGILVDDAIIVVENVERIMsEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILFS 481
Cdd:NF033617 394 IGLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIIS 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 482 ALLALSLTPALCASFLKQVPKGHHHAKRgffgwFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLPSS 561
Cdd:NF033617 473 GIVALTLTPMMCSRLLKANEKPGRFARA-----VDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKE 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 562 FLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGFSFFgSGQNAGLAFVTLKDWSERDAdnSAQ 641
Cdd:NF033617 548 LAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGN-PGDNTGFGIINLKPWDERDV--SAQ 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 642 SIAGRATMAMSQIKDAISFALSPPAIQGlGTTGGFSFRLQDRAGLGQAALAEARDQLLDLASQSKVLTGVRFEGMPDAAQ 721
Cdd:NF033617 625 EIIDRLRPKLAKVPGMDLFLFPLQDLPG-GAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPE 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 722 VSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLSAFAD 801
Cdd:NF033617 704 LNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAK 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 802 VEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEMERLVAE-LPAGFGYEWTGQSLQEIQSGSQAPLLIALSCLLVF 880
Cdd:NF033617 784 IEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKElLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIY 863
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 881 LCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKEL-REQGKSLIDSTL 959
Cdd:NF033617 864 LVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELqRHQGLSRREAIY 943
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|..
gi 499271021 960 EAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVL 1011
Cdd:NF033617 944 QAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLF 995
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
5-1013 |
6.97e-159 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 496.66 E-value: 6.97e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 5 FIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFeSSTSS 84
Cdd:PRK09579 7 FIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM-TSVSR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 85 SGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGVQVDEAGAGFLLIISLTStdGSMDAIGLGDYLSRNVLS 164
Cdd:PRK09579 86 QNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYS--EEMSNPQITDYLSRVIQP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 165 EIQRVPGVGRAQLFATER-SMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGAQpnpitqQVTAPVVIKGQLSSP 243
Cdd:PRK09579 164 KLATLPGMAEAEILGNQVfAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGE------YVVTSINASTELKSA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 244 EEFGAIVLRANADgSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPEGLEY 323
Cdd:PRK09579 238 EAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 324 SIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVLAIG 403
Cdd:PRK09579 317 SIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 404 ILVDDAIIVVENVERIMsEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILFSAL 483
Cdd:PRK09579 397 LVVDDAIVVVENIHRHI-EEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGI 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 484 LALSLTPALCASFLKqvpkgHHHAKRGFFGWFNRGFDRTSHGYTRAVGGIVrRTGRFMVIYLALLAGLGWAFLQLPSSFL 563
Cdd:PRK09579 476 VALTLSPMMCALLLR-----HEENPSGLAHRLDRLFERLKQRYQRALHGTL-NTRPVVLVFAVIVLALIPVLLKFTQSEL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 564 -PDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGFsffgSGQNAGLAFVTLKDWSERdaDNSAQS 642
Cdd:PRK09579 550 aPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGF----NGVQSGIGGFLLKPWNER--ERTQME 623
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 643 IAGRATMAMSQIKDAISFALSPPAIQGLGTTGGFSFRLQDRAGLgqAALAEARDQLLDLASQSKVLTGVRFEGMPDAAQV 722
Cdd:PRK09579 624 LLPLVQAKLEEIPGLQIFGFNLPSLPGTGEGLPFQFVINTANDY--ESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEV 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 723 SVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLSAFADV 802
Cdd:PRK09579 702 VVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLITL 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 803 EWVKAPTQTVGYNGYPAVRISGeaAPGYSSGDAIAEMERLVAE-LPAGFGYEWTGQSLQEIQSGSQAPLLIALSCLLVFL 881
Cdd:PRK09579 782 SDRARPRQLNQFQQLNSAIISG--FPIVSMGEAIETVQQIAREeAPEGFAFDYAGASRQYVQEGSALWVTFGLALAIIFL 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 882 CLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELR-EQGKSLIDSTLE 960
Cdd:PRK09579 860 VLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRhEQGLSRREAIEE 939
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|...
gi 499271021 961 AAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAI 1013
Cdd:PRK09579 940 AAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTL 992
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
3-1011 |
7.30e-136 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 436.00 E-value: 7.30e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 3 SFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGL------- 75
Cdd:COG3696 7 RFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVkevrsis 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 76 ---LYFesstsssgsvsIDATFQPGTDPSQASVDIQNRVQRVEPRLPDpvrqqGVQV----DEAGAGFLLIISLTSTDGS 148
Cdd:COG3696 87 rfgLSV-----------VTVIFEDGTDIYWARQLVLERLQQVREQLPA-----GVTPelgpISTGLGEIYQYTLESDPGK 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 149 MDAIGLGDYLSRNVLSEIQRVPGVgrAQLFA---TERSMRVWLDPDKMLGLNLTAADVTAAIQAQNaQIASGSIGAQPNp 225
Cdd:COG3696 151 YSLMELRTLQDWVIRPQLRSVPGV--AEVNSfggFVKQYQVLVDPAKLRAYGLTLDDVIEALERNN-ANVGGGYIERGG- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 226 itQQVTapVVIKGQLSSPEEFGAIVLrANADGSAVRLRDVARLEIGGEsytfsTR-----LNGSPSAAIA-VQLSPSGNA 299
Cdd:COG3696 227 --QEYL--VRGIGLIRSLEDIENIVV-KTRNGTPVLLRDVAEVRIGPA-----PRrgaatLNGEGEVVGGiVLMLKGENA 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 300 MSTSAAIKARMDELAEFFPEGLEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGT 379
Cdd:COG3696 297 LEVIEAVKAKLAELKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFA 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 380 CAVMLAMGFSINVLTMFGMVLAIGILVDDAIIVVENVERIMSEEGLTPKDATR-----KAMKQITGAVIGITLVLASVFI 454
Cdd:COG3696 377 FIVMRLFGISANLMSLGGLAIDFGIIVDGAVVMVENILRRLEENRAAGTPRERlevvlEAAREVRRPIFFATLIIILVFL 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 455 PMAFFPGAVGVIYRQFSLTMVVSILFSALLALSLTPALCASFLKQVPKGHHHakrgffgWFNRGFDRtshGYTRAVGGIV 534
Cdd:COG3696 457 PIFTLEGVEGKLFRPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKEN-------PLVRWLKR---LYRPLLRWAL 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 535 RRTGRFMVIYLALLAGLGWAFLQLPSSFLPDEDQGFVIVMMQLP---SEATANRTTEVIEQT-------ETIFGQ----E 600
Cdd:COG3696 527 RHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPpgiSLEESVELGQQVERIlksfpevESVVSRtgraE 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 601 KAVDTivaingfsffgSGQNAGLAFVTLKDWSERdadnsaqsiagRATMAMSQIKDAISFALSppAIQGLGTtgGFSFRL 680
Cdd:COG3696 607 DATDP-----------MGVNMSETFVILKPRSEW-----------RSGRTKEELIAEMREALE--QIPGVNF--NFSQPI 660
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 681 QDR-----AGLgQAALA-----EARDQLLDLASQ-SKVLTGV---------RFEGMPdaaQVSVNIDREKANTFGVTFAD 740
Cdd:COG3696 661 QMRvdellSGV-RADVAvkifgDDLDVLRRLAEQiEAVLKTVpgaadvqveRVTGLP---QLDIRIDRDAAARYGLNVAD 736
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 741 INSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLSAFADVEWVKAPTQ---------- 810
Cdd:COG3696 737 VQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQisrengrrri 816
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 811 TVGYNgypaVRisgeaapGYSSGDAIAEMERLVAE---LPAGFGYEWTGQSLQEIQSGSQAPLLIALSCLLVFLCLAALY 887
Cdd:COG3696 817 VVQAN----VR-------GRDLGSFVAEAQAKVAEqvkLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLLLYLAF 885
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 888 ESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLIDSTLEAAHLRFR 967
Cdd:COG3696 886 GSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERLR 965
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....
gi 499271021 968 PILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVL 1011
Cdd:COG3696 966 PVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLL 1009
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
3-1011 |
1.34e-113 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 375.99 E-value: 1.34e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 3 SFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFESST 82
Cdd:PRK10614 5 ALFIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 83 SSSGSVSIdATFQPGTDPSQASVDIQNRVQRVEPRLPD--PVRQQGVQVDEAGAGfLLIISLTSTDGSMDAigLGDYLSR 160
Cdd:PRK10614 85 SLGSTRII-LQFDFDRDINGAARDVQAAINAAQSLLPSgmPSRPTYRKANPSDAP-IMILTLTSDTYSQGQ--LYDFAST 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 161 NVLSEIQRVPGVGRAQLFATE-RSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGaqpnpiTQQVTAPVVIKGQ 239
Cdd:PRK10614 161 QLAQTISQIDGVGDVDVGGSSlPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVE------DGTHRWQIQTNDE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 240 LSSPEEFGAIVLRANaDGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPE 319
Cdd:PRK10614 235 LKTAAEYQPLIIHYN-NGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 320 GLEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMV 399
Cdd:PRK10614 314 AIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALT 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 400 LAIGILVDDAIIVVENVERIMsEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSIL 479
Cdd:PRK10614 394 IATGFVVDDAIVVLENISRHL-EAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIG 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 480 FSALLALSLTPALCASFLKQVPKGHHHAKRGffgwFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLP 559
Cdd:PRK10614 473 ISLLVSLTLTPMMCAWLLKSSKPREQKRLRG----FGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIP 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 560 SSFLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGfsffGSGQNAGLAFVTLKDWSERdaDNS 639
Cdd:PRK10614 549 KTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTG----GSRVNSGMMFITLKPLSER--SET 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 640 AQSIAGRATMAMSQIKDAISFALSPPAIQ--GLGTTGGFSFRLQDRAglgQAALAEARDQLLDLASQSKVLTGVRFEGMP 717
Cdd:PRK10614 623 AQQVIDRLRVKLAKEPGANLFLMAVQDIRvgGRQSNASYQYTLLSDD---LAALREWEPKIRKALAALPELADVNSDQQD 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 718 DAAQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLS 797
Cdd:PRK10614 700 KGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLS 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 798 AFADVEWVKAPTqTVGYNGYPAVR-ISGEAAPGYSSGDAIAEMERLVAEL--PAGF--GYEWTGQSLQEIQSgSQAPLLI 872
Cdd:PRK10614 780 YFAKWQPANAPL-SVNHQGLSAAStISFNLPTGKSLSDASAAIERAMTQLgvPSTVrgSFAGTAQVFQETMN-SQLILIL 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 873 AlSCLLVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGK 952
Cdd:PRK10614 858 A-AIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGN 936
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 953 -SLIDSTLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVL 1011
Cdd:PRK10614 937 lTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLL 996
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
5-1013 |
6.02e-112 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 371.76 E-value: 6.02e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 5 FIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFeSSTSS 84
Cdd:PRK10503 16 FILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQM-SSQSS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 85 SGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQGV--QVDEAGAGfllIISLTSTDGSMDAIGLGDYLSRNV 162
Cdd:PRK10503 95 GGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVysKVNPADPP---IMTLAVTSTAMPMTQVEDMVETRV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 163 LSEIQRVPGVGRAQLFATER-SMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGAQPNPITqqvtapVVIKGQLS 241
Cdd:PRK10503 172 AQKISQVSGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVT------LSANDQMQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 242 SPEEFGAIVLrANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDELAEFFPEGL 321
Cdd:PRK10503 246 SAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSV 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 322 EYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVLA 401
Cdd:PRK10503 325 KVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIA 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 402 IGILVDDAIIVVENVERIMsEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILFS 481
Cdd:PRK10503 405 TGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILIS 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 482 ALLALSLTPALCASFLKQVPKGHHHAkrgFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLPSS 561
Cdd:PRK10503 484 AVVSLTLTPMMCARMLSQESLRKQNR---FSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKG 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 562 FLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQEKAVDTIVAINGFSFFGSGQNAGLAFVTLKDWSERdaDNSAQ 641
Cdd:PRK10503 561 FFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDER--DDRVQ 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 642 SIAGRATMAMSQIKDaISFALSPP---AIQGLGTTGGFSFRLQdraGLGQAALAEARDQLLDLASQSKVLTGVRFEGMPD 718
Cdd:PRK10503 639 KVIARLQTAVAKVPG-VDLYLQPTqdlTIDTQVSRTQYQFTLQ---ATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDK 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 719 AAQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTADLLNLNVRNSNGGMVPLSA 798
Cdd:PRK10503 715 GLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSS 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 799 FADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDA---IAEMERLVAeLPAGFGYEWTGQSLQEIQSGSQAPLLIALS 875
Cdd:PRK10503 795 IATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAvqaIMDTEKTLN-LPADITTQFQGSTLAFQSALGSTVWLIVAA 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 876 CLLVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFA-KELREQGKSL 954
Cdd:PRK10503 874 VVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFAlAAEREQGMSP 953
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 499271021 955 IDSTLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAI 1013
Cdd:PRK10503 954 RDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTL 1012
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
11-1013 |
1.19e-93 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 321.71 E-value: 1.19e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 11 FAWVV---AIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQSVTRLIEDELNGVEGLLYFESSTSSSGS 87
Cdd:TIGR00914 12 QRWLVllaTLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSRYGLS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 88 VsIDATFQPGTDPSQASVDIQNRVQRVEPRLPDPVRQQgVQVDEAGAGFLLIISLTSTDGSMDAIG----------LGDY 157
Cdd:TIGR00914 92 Q-VTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPE-MGPISTGLGEIFLYTVEAEEGARKKDGgaytltdlrtIQDW 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 158 LSRnvlSEIQRVPGVGR-AQLFATERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSI---GAQpnpitQQVTAP 233
Cdd:TIGR00914 170 IIR---PQLRTVPGVAEvNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIerrGEQ-----YLVRAP 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 234 vvikGQLSSPEEFGAIVLrANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAMSTSAAIKARMDEL 313
Cdd:TIGR00914 242 ----GQVQSMDDIRNIVI-ATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 314 AEFFPEGLEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVL 393
Cdd:TIGR00914 317 NKTLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLM 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 394 TMfgMVLAIGILVDDAIIVVENVERIMSE----EGLTPKDATR-----KAMKQITGAVIGITLVLASVFIPMAFFPGAVG 464
Cdd:TIGR00914 397 SL--GALDFGLIVDGAVVIVENAHRRLAEaqhhHGRQLTLKERlhevfAASREVRRPLIFGQLIITLVFLPIFTLTGVEG 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 465 VIYRQFSLTMVVSILFSALLALSLTPALCASFL-KQVPKGHhhakrgffgwfNRGFDRTSHGYTRAVGGIVRRTGRFMVI 543
Cdd:TIGR00914 475 KMFHPMAFTVVLALAGAMILSLTFVPAAVALFIrGKVAEKE-----------NRLMRVLKRRYEPLLERVLAWPAVVLGA 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 544 YLALLAGLGWAFLQLPSSFLPDEDQGFVIVM-MQLPSeATANRTTEVIEQTETIFGQEKAVDTIVAINGFSFFGSGQ--- 619
Cdd:TIGR00914 544 AAVSIVLVVWIASRVGGEFIPSLNEGDLAYQaLRIPG-TSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPmpp 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 620 NAGLAFVTLK---DWSE---------RDADNSAQSIAGRATMAMSQIK----DAISFALSPPAIQGLGTTggfsfrLQDR 683
Cdd:TIGR00914 623 NASDTYIILKpesQWPEgkktkedliEEIQEATVRIPGNNYEFTQPIQmrfnELISGVRSDVAVKVFGDD------LDDL 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 684 AGLGQAALAEARDqlLDLASQSKVltgVRFEGMPdaaQVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRM 763
Cdd:TIGR00914 697 DATAEKISAVLKG--VPGAADVKV---EQTTGLP---YLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRR 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 764 QRVTVQADETKRMQTADLLNLNVR--NSNGGM---VPLSAFADVEWVKAPTQTVGYNGYPAVRISGEAApGYSSGDAIAE 838
Cdd:TIGR00914 769 FDIVIRLPESLRESPQALRQLPIPlpLSEDARkqfIPLSDVADLRVSPGPNQISRENGKRRVVVSANVR-GRDLGSFVDD 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 839 MERLVAE---LPAGFGYEWTGQsLQEIQSGSQA-PLLIALSCLLVFLCLAALYESWSIPVSVIMVVPLGVIGAVLAVTMR 914
Cdd:TIGR00914 848 AKKAIAEqvkLPPGYWITWGGQ-FEQLQSATKRlQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLR 926
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 915 DMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLIDSTLEAAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQ 994
Cdd:TIGR00914 927 GIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQ 1006
|
1050
....*....|....*....
gi 499271021 995 RAIGTGVMGGMISATVLAI 1013
Cdd:TIGR00914 1007 RPLATVVIGGIITATLLTL 1025
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
286-1011 |
8.23e-19 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 92.23 E-value: 8.23e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 286 SAAIAVQL--SPSGNAMSTSAAIKARMDELAEFFPEGLEYSI---PYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQ 360
Cdd:COG1033 161 ATLIVVTLdpDPLSSDLDRKEVVAEIRAIIAKYEDPGVEVYLtgfPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 361 NVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVLAIGILVDDAIIVvenVERIMSE--EGLTPKDATRKAMKQI 438
Cdd:COG1033 241 SLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHL---LNRYREErrKGLDKREALREALRKL 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 439 TGAVIGITLVLASVFIPMAFFPgaVGVIyRQFSLTMVVSILFSALLALSLTPALCASFLKQVPKGHHHAKRGFFGWFNRG 518
Cdd:COG1033 318 GPPVLLTSLTTAIGFLSLLFSD--IPPI-RDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLLAK 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 519 FDRTshgytravggIVRRTGRFMVIYLALLAGLGWAFLQLPSSFLPDEDqgfvivmmqLPSEATANRTTEVIEQTetiFG 598
Cdd:COG1033 395 LARF----------VLRRPKVILVVALVLAVVSLYGISRLKVEYDFEDY---------LPEDSPIRQDLDFIEEN---FG 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 599 QEKAVDTIVaingfsffgsgqnaglafvtlkDWSERDADNSAQsiagratmAMSQIKDaisfalsppaiqglgttggFSF 678
Cdd:COG1033 453 GSDPLEVVV----------------------DTGEPDGLKDPE--------VLKEIDR-------------------LQD 483
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 679 RLQDRAGLGQAalaeardqlLDLASQSKVLTGVRFEGMPDAAQvsvnIDREKANTFGVTFADinSTISTNLGSSYVNDfp 758
Cdd:COG1033 484 YLESLPEVGKV---------LSLADLVKELNQALNEGDPKYYA----LPESRELLAQLLLLL--SSPPGDDLSRFVDE-- 546
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 759 nAGRMQRVTVQADETKRMQTADLLNlNVRnsnggmvplsafadvEWVKAPTQTVGYNgypaVRISGEAApgyssgdAIAE 838
Cdd:COG1033 547 -DYSAARVTVRLKDLDSEEIKALVE-EVR---------------AFLAENFPPDGVE----VTLTGSAV-------LFAA 598
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 839 MERLVAElpagfgyewtgqslqeiqsgSQAPLLIaLSCLLVFLCLAALYESWSIP-VSVI-MVVPLGVIGAVLAVTmrdm 916
Cdd:COG1033 599 INESVIE--------------------SQIRSLL-LALLLIFLLLLLAFRSLRLGlISLIpNLLPILLTFGLMGLL---- 653
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 917 pnDVYFKVGLIAI----IGLSAKNAILIIEFAKELREQGKSLIDSTLEAAHLRFRPILMTSLAFTLGVLPLAIatgASSG 992
Cdd:COG1033 654 --GIPLNIATAVVasiaLGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLF---SSFP 728
|
730 740
....*....|....*....|...
gi 499271021 993 SQRAIGT----GVMGGMISATVL 1011
Cdd:COG1033 729 PLADFGLllalGLLVALLAALLL 751
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
277-611 |
2.20e-10 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 64.79 E-value: 2.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 277 FSTRLNGSPSA---AIAVQLSPSGNAMSTSAAIKARM-DELAEFFPEGLEYSI---PYDTSPFVAVSIEKVLHTLVEAVG 349
Cdd:COG2409 101 WDDPAAGLVSEdgkAALVTVTLDGDAGDEAAEAVDALrDAVAAAPAPGLTVYVtgpAALAADLNEAFEEDLGRAELITLP 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 350 LVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMG-------FSINVLTMfgMVLAIGIlvDDAIIVV----ENVER 418
Cdd:COG2409 181 VALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAaftdvssFAPNLLTM--LGLGVGI--DYALFLVsryrEELRA 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 419 imseeGLTPKDATRKAMKQITGAVI--GITLVLAS---VFIPMAFF-----PGAVGVIyrqfsLTMVVSILFsallalsl 488
Cdd:COG2409 257 -----GEDREEAVARAVATAGRAVLfsGLTVAIALlglLLAGLPFLrsmgpAAAIGVA-----VAVLAALTL-------- 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 489 TPALCASFlkqvpkgHHHAKRGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRFMVIYLALLAGLGWAFLQLPSSFlPDEDq 568
Cdd:COG2409 319 LPALLALL-------GRRVFWPRRPRRRRAAAPESGFWRRLARAVVRRPVPVLVAAVAVLLALALPALGLRLGL-PDAD- 389
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 499271021 569 gfvivmmQLPSEATANRTTEVIEQTetiFGQEKAVDTIVAING 611
Cdd:COG2409 390 -------SLPADSPSRQGYDALAEH---FPPGSNGPLTVVVES 422
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
331-478 |
2.15e-04 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 43.40 E-value: 2.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 331 PFVAVSIEKVLHTLVEAV---GLVFLVMFLFLQNVRYTIIPTIVVPVALLG----TCAVMLAMGFSINVLTMFGMVLAIG 403
Cdd:TIGR00916 32 PVVGTVGPTLGGELIKAGiiaLLIGLVLVLLYMLLRYEWRGAIAAIAALVHdvilILGVLSLFGATLTLPGIAGLLTIIG 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499271021 404 ILVDDAIIVVENV-ERIMSEEGLTPKDATRKAMKQITGAVI--GITLVLASVFIpMAFfpgAVGVIyRQFSLTMVVSI 478
Cdd:TIGR00916 112 YSVDDTVVIFDRIrEELRKYKGRTFREAINLGINQTLSRIIdtNVTTLLAVLAL-YVF---GGGAI-KGFALTLGIGV 184
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
336-478 |
2.58e-04 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 44.72 E-value: 2.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 336 SIEKVLHTLVEAVGLVFLVMFlflqnVRYTIiPTIVVPVALLG----TCAVMLAMGFsinVLTM---FGMVLAIGILVDD 408
Cdd:COG0342 269 SIEKGLIAGLIGLLLVALFML-----LYYRL-PGLVANIALALnvvlLLGVLSLLGA---TLTLpgiAGIILTIGMAVDA 339
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499271021 409 AIIVvenVERIMSE--EGLTPKDATRKAMKQITGAVIG--ITLVLASVfiPMAFFpgAVGVIyRQFSLTMVVSI 478
Cdd:COG0342 340 NVLI---FERIREElrAGRSLRAAIEAGFKRAFSTILDanVTTLIAAV--VLFVL--GTGPV-KGFAVTLILGI 405
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
336-478 |
5.18e-04 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 43.82 E-value: 5.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 336 SIEKVLHTLVEAVGLVFLVMFLFLQnvRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVLAIGILVDDAIIVven 415
Cdd:TIGR01129 246 SIEAGIKAGLIGLVLVLVFMILYYR--LFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLI--- 320
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499271021 416 VERIMSE--EGLTPKDAT----RKAMKQITGAviGITLVLASVFIpMAFFPGAVgviyRQFSLTMVVSI 478
Cdd:TIGR01129 321 YERIKEElrLGKSVRQAIeagfERAFSTIFDA--NITTLIAALIL-YVFGTGPV----KGFAVTLAIGI 382
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
347-410 |
9.90e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 43.30 E-value: 9.90e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499271021 347 AVGLVFLVMFLFLQNVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVLAIGILVDDAI 410
Cdd:COG4258 648 ALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL 711
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
347-478 |
2.97e-03 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 41.76 E-value: 2.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 347 AVGLVFLVMFLFlqnvrYtIIPTIVVPVALLGTCAVMLAMGFSIN-VLTM---FGMVLAIGILVDDAIIVvenVERIMSE 422
Cdd:PRK13024 275 GFALIFLFMLVY-----Y-GLPGLIANIALLLYIFLTLGALSSLGaVLTLpgiAGLVLGIGMAVDANVLI---FERIKEE 345
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 423 --EGLTPKDATRKAMKQITGAVI--GITLVLASVfipMAFFPGAVGViyRQFSLTMVVSI 478
Cdd:PRK13024 346 lrKGKSLKKAFKKGFKNAFSTILdsNITTLIAAA---ILFFFGTGPV--KGFATTLIIGI 400
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
863-1008 |
5.87e-03 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 39.16 E-value: 5.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 863 QSGSQAPLLIALSCLLVFLCLAALYE-SWSIPVSVIMVVPLGVIGAVLAVTMRDMpnDVYFKVGLIAIIGLSAKNAILII 941
Cdd:TIGR00916 44 ELIKAGIIALLIGLVLVLLYMLLRYEwRGAIAAIAALVHDVILILGVLSLFGATL--TLPGIAGLLTIIGYSVDDTVVIF 121
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499271021 942 EFAKE--LREQGKSLIDSTLEAAHLRFRPILMTSLAFTLGVLPL-AIATGASSGSQRAIGTGVMGGMISA 1008
Cdd:TIGR00916 122 DRIREelRKYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALyVFGGGAIKGFALTLGIGVIAGTYSS 191
|
|
| |
