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Conserved domains on  [gi|499272820|ref|WP_010970213|]
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ABC transporter permease [Sinorhizobium meliloti]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 5-312 2.85e-123

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 355.53  E-value: 2.85e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   5 RFVLTRPLQFLPVIFGISIITFILVRLIPGDPARNLLGARATPSAIAKIRAQYGLDEPMWQQYFYFLKNLADGEMGKSIL 84
Cdd:COG0601    3 RYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  85 YKIDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFSVKLDVL 164
Cdd:COG0601   83 YGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 165 PVSGYG---ATFGDKLAHLILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINL 241
Cdd:COG0601  163 PVSGRVspwEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTV 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499272820 242 LAVNIGWLIGGTVVVESVFALPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFIADIVTVAVDPRVKL 312
Cdd:COG0601  243 LGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRL 313
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 5-312 2.85e-123

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 355.53  E-value: 2.85e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   5 RFVLTRPLQFLPVIFGISIITFILVRLIPGDPARNLLGARATPSAIAKIRAQYGLDEPMWQQYFYFLKNLADGEMGKSIL 84
Cdd:COG0601    3 RYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  85 YKIDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFSVKLDVL 164
Cdd:COG0601   83 YGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 165 PVSGYG---ATFGDKLAHLILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINL 241
Cdd:COG0601  163 PVSGRVspwEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTV 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499272820 242 LAVNIGWLIGGTVVVESVFALPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFIADIVTVAVDPRVKL 312
Cdd:COG0601  243 LGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRL 313
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 5-312 2.76e-68

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 215.33  E-value: 2.76e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   5 RFVLTRPLQFLPVIFGISIITFILVRLIPGDPARNLL---GARATPSAIAKIRAQYGLDEPMWQQYFYFLKNLADGEMGK 81
Cdd:PRK10352   3 RYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLrlsNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  82 SILYKIDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFSVKL 161
Cdd:PRK10352  83 SFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 162 DVLPVSGYGAtfgdkLAHLILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINL 241
Cdd:PRK10352 163 QWLPAMGYGG-----WQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITA 237

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499272820 242 LAVNIGWLIGGTVVVESVFALPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFIADIVTVAVDPRVKL 312
Cdd:PRK10352 238 VGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRR 308
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 115-311 4.09e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 101.99  E-value: 4.09e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  115 AVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFsvkldvlpvsgygatFGDKLAHLILPSLTVALSLSTV 194
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA---------------ILSILGHGILPAIILALLGWAG 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  195 LVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINLLAVNIGWLIGGTVVVESVFALPGMGQLLVRAIF 274
Cdd:pfam00528  66 YARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAIL 145

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 499272820  275 SRDYMVVQGVAMVFACATVLVNFIADIVTVAVDPRVK 311
Cdd:pfam00528 146 GYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 100-297 4.95e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 77.70  E-value: 4.95e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 100 TIALVLSSVVLAVLIAVPMAALAARNSGKApDHIVRVVSTFGIGFPPFWLGLMLMILFSVKLDvlpvsgygatfGDKLAH 179
Cdd:cd06261    4 TLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG-----------WGILPG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 180 LILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINLLAVNIGWLIGGTVVVESV 259
Cdd:cd06261   72 LGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFL 151

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 499272820 260 FALPGMG-QLLVRAIFSRDYMVVQGVAMVFACATVLVNF 297
Cdd:cd06261  152 GGGEAPGpGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 5-312 2.85e-123

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 355.53  E-value: 2.85e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   5 RFVLTRPLQFLPVIFGISIITFILVRLIPGDPARNLLGARATPSAIAKIRAQYGLDEPMWQQYFYFLKNLADGEMGKSIL 84
Cdd:COG0601    3 RYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  85 YKIDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFSVKLDVL 164
Cdd:COG0601   83 YGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 165 PVSGYG---ATFGDKLAHLILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINL 241
Cdd:COG0601  163 PVSGRVspwEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTV 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499272820 242 LAVNIGWLIGGTVVVESVFALPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFIADIVTVAVDPRVKL 312
Cdd:COG0601  243 LGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRL 313
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 5-312 2.76e-68

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 215.33  E-value: 2.76e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   5 RFVLTRPLQFLPVIFGISIITFILVRLIPGDPARNLL---GARATPSAIAKIRAQYGLDEPMWQQYFYFLKNLADGEMGK 81
Cdd:PRK10352   3 RYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLrlsNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  82 SILYKIDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFSVKL 161
Cdd:PRK10352  83 SFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 162 DVLPVSGYGAtfgdkLAHLILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINL 241
Cdd:PRK10352 163 QWLPAMGYGG-----WQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITA 237

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499272820 242 LAVNIGWLIGGTVVVESVFALPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFIADIVTVAVDPRVKL 312
Cdd:PRK10352 238 VGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRR 308
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 6-311 8.65e-66

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 208.80  E-value: 8.65e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   6 FVLTRPLQFLPVIFGISIITFILVRLIPGDPARNLLGARATPSAIAKIRAQYGLDEPMWQQYFYFLKNLADGEMGKSILY 85
Cdd:PRK15081   4 YVIKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTSMVS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  86 KIDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFSVKLDVLP 165
Cdd:PRK15081  84 RRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELGWLP 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 166 VSGygatfGDKLAHLILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINLLAVN 245
Cdd:PRK15081 164 TVG-----ADSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQ 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499272820 246 IGWLIGGTVVVESVFALPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFIADIVTVAVDPRVK 311
Cdd:PRK15081 239 FGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
5-311 5.34e-56

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 184.63  E-value: 5.34e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   5 RFVLTRPLQFLPVIFGISIITFILVRLIPGDPARNLLGARA-TPSAIAKIRAQYGLDEPMWQQYFYFLKNLADGEMGKSI 83
Cdd:PRK10914   3 QFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGiSPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  84 LYKIDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFSVKLDV 163
Cdd:PRK10914  83 KSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 164 LPVSGYGA--------------------------TFGDKLAHLILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARA 217
Cdd:PRK10914 163 TPVSGRVSdmvflddsnpltgfmlidtaiwgedgNFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 218 RGMPERIVFWRHVVPNSLVPTINLLAVNIGWLIGGTVVVESVFALPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNF 297
Cdd:PRK10914 243 KGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNL 322

                        330
                 ....*....|....
gi 499272820 298 IADIVTVAVDPRVK 311
Cdd:PRK10914 323 LVDLLYGVVNPRIR 336
oppB PRK09471
oligopeptide ABC transporter permease OppB;
5-311 2.84e-51

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 171.40  E-value: 2.84e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   5 RFVLTRPLQFLPVIFGISIITFILVRLIPGDParnLLGARA-TPSAIAKIRAQYGLDEPMWQQYFYFLKNLADGEMGKSI 83
Cdd:PRK09471   3 KFILRRCLEAIPTLFILITISFFMMRLAPGSP---FTGERTlPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  84 LYK-IDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFSVKLD 162
Cdd:PRK09471  80 KYKdYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAITLH 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 163 VLPVSGYGatfGDKLAHLILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINLL 242
Cdd:PRK09471 160 WLPGGGWN---GGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYM 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499272820 243 AVNIGWLIGGTVVVESVFALPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFIADIVTVAVDPRVK 311
Cdd:PRK09471 237 GPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
YejB COG4174
ABC-type microcin C transport system, permease component YejB [Secondary metabolites ...
 6-310 1.36e-34

ABC-type microcin C transport system, permease component YejB [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443333 [Multi-domain]  Cd Length: 363  Bit Score: 129.15  E-value: 1.36e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   6 FVLTRPLQFLPVIFGISIITFILVRLIPGDPARNLL----------------------------------GARA-TPSAI 50
Cdd:COG4174    4 YILRRLLLMIPTLLGIMLINFVIVQFAPGGPVEQVIaqlqgtgggatgrisggggdagggaaagggskyrGARGlDPEFI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  51 AKIRAQYGLDEPMWQQYFYFLKNLADGEMGKSILYKIDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSGKAP 130
Cdd:COG4174   84 AELEKQYGFDKPAHERFLLMLKNYLRFDFGESYFRDISVIDLILEKLPVSISLGLWSTLLTYLISIPLGIRKAVRDGSRF 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 131 DHIVRVVSTFGIGFPPFWLGLMLMILFS--VKLDVLPVSG----------YGATFGDKLAHLILPSLTVALSLSTVLVRS 198
Cdd:COG4174  164 DVWTSTVIIVGYAIPGFLFAILLIVLFAggSYFDWFPLRGltsdnwdqlsWWGKILDYLWHLTLPVTAMVIGGFATLTLL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 199 LRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTI-NLLAVNIGWLIGGTVVVESVFALPGMGQLLVRAIFSRD 277
Cdd:COG4174  244 TKNSFLDEIRKQYVLTARAKGLSERRVLYGHVFRNAMLIVIaGFPAAFIGAFFTGSLLIETIFSLDGLGLLGFEAVVNRD 323

                        330       340       350
                 ....*....|....*....|....*....|...
gi 499272820 278 YMVVQGVAMVFACATVLVNFIADIVTVAVDPRV 310
Cdd:COG4174  324 YPVVFGTLYIFTLIGLVLKLISDLTYVLVDPRI 356
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 6-310 1.10e-29

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 116.00  E-value: 1.10e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   6 FVLTRPLQFLPVIFGISIITFILVRLIPGDPARNLL-------------------------------------GARA-TP 47
Cdd:PRK15133   4 YLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIaaiefgqagglpgaggegvrashaqtgvgnisdsnyrGGRGlDP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  48 SAIAKIRAQYGLDEPMWQQYFYFLKNLADGEMGKSILYKIDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSG 127
Cdd:PRK15133  84 EVIAEITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNG 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 128 KAPDHIVRVVSTFGIGFPPFWLGLMLMILFS--VKLDVLPVSG----------YGATFGDKLAHLILPSL-TVALSLSTV 194
Cdd:PRK15133 164 SRFDVWSSAFIIIGYAIPAFLFAILLIVFFAggSYFDLFPLRGlvsanfdslpWYQKITDYLWHITLPVLaTVIGGFAAL 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 195 LVRSLRAAMIESLKSDVATaARARGMPERIVFWRHVVPNSLVPTI-NLLAVNIGWLIGGTVVVESVFALPGMGQLLVRAI 273
Cdd:PRK15133 244 TMLTKNSFLDEIRKQYVVT-ARAKGVSEKNILWKHVFRNAMLLVIaGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEAT 322

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 499272820 274 FSRDYMVVQGVAMVFACATVLVNFIADIVTVAVDPRV 310
Cdd:PRK15133 323 VSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
PRK15110 PRK15110
peptide ABC transporter permease SapB;
6-308 1.62e-27

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 109.01  E-value: 1.62e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820   6 FVLTRPLQFLPVIFGISIITFILVRLIPGDParnLLGAratpsaiakiraqygldePMWQQYFYFLKNLADGEMGKSILY 85
Cdd:PRK15110   4 FTLRRLLLLIVTLFLLTLVGFSLSYFTPHAP---LQGA------------------SLWDAWVFWFNGLLHWDFGVSSIN 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  86 KIDVLKLIATRVEPTIALVLSSVVLAVLIAVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFSVKLDVLP 165
Cdd:PRK15110  63 GQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWLALLLTLFFSLTLGWLP 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 166 VSG----------------YGATFGDK----------LAHLILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARARG 219
Cdd:PRK15110 143 VSGrfdllyevkpvtgfalIDAWLSDSpwrdemimsaIRHMILPVITLAVAPTTEVIRLMRISTIEVYDQNYVKAAATRG 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 220 MPERIVFWRHVVPNSLVPTINLLAVNIGWLIGGTVVVESVFALPGMGQLLVRAIFSRDYMVVQGVAMVFACATVLVNFIA 299
Cdd:PRK15110 223 LSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVVGSLVIIVNVLS 302


                 ....*....
gi 499272820 300 DIVTVAVDP 308
Cdd:PRK15110 303 DILGAMANP 311
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 115-311 4.09e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 101.99  E-value: 4.09e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  115 AVPMAALAARNSGKAPDHIVRVVSTFGIGFPPFWLGLMLMILFsvkldvlpvsgygatFGDKLAHLILPSLTVALSLSTV 194
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA---------------ILSILGHGILPAIILALLGWAG 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  195 LVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINLLAVNIGWLIGGTVVVESVFALPGMGQLLVRAIF 274
Cdd:pfam00528  66 YARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAIL 145

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 499272820  275 SRDYMVVQGVAMVFACATVLVNFIADIVTVAVDPRVK 311
Cdd:pfam00528 146 GYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 100-297 4.95e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 77.70  E-value: 4.95e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 100 TIALVLSSVVLAVLIAVPMAALAARNSGKApDHIVRVVSTFGIGFPPFWLGLMLMILFSVKLDvlpvsgygatfGDKLAH 179
Cdd:cd06261    4 TLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG-----------WGILPG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 180 LILPSLTVALSLSTVLVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINLLAVNIGWLIGGTVVVESV 259
Cdd:cd06261   72 LGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFL 151

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 499272820 260 FALPGMG-QLLVRAIFSRDYMVVQGVAMVFACATVLVNF 297
Cdd:cd06261  152 GGGEAPGpGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 4-103 4.70e-13

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 64.55  E-value: 4.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820    4 YRFVLTRPLQFLPVIFGISIITFILVRLIPGDPARNLLGARATPSAIAKIRAQYGLDEPMWQQYFYFLKNLADGEM---- 79
Cdd:pfam19300   2 LRFLVRRTLGAVVILLIISAVTFFLFYAIPRDPARLACGKNCTPETLALIRHNLGLDKPIPVQYWHFLSGIFAGRDfgav 81

                          90       100       110
                  ....*....|....*....|....*....|..
gi 499272820   80 --------GKSILYKIDVLKLIATRVEPTIAL 103
Cdd:pfam19300  82 ghcpapclGYSFANNEPVWDTIMDRFPTTLSL 113
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 78-250 5.85e-06

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 47.03  E-value: 5.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  78 EMGKSILYKIdvlkLIATRVepTIALVLSSVVLAVLIAVPMAALAARNSGKAPDHIVRVVSTFgIGFPpfwlGLMLMILF 157
Cdd:COG1173   65 QLGRDVLSRL----LYGARI--SLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVL-LAFP----SLLLAIAL 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 158 SvkldvlpvsgygATFGDKLAHLILpslTVALSLSTVLVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVP 237
Cdd:COG1173  134 V------------AVLGPGLLNVIL---ALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPP 198

                        170
                 ....*....|...
gi 499272820 238 TINLLAVNIGWLI 250
Cdd:COG1173  199 LIVQATLGIASAI 211
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 101-309 8.78e-05

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 42.73  E-value: 8.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 101 IALVLSSVVLAVLIAVPMAALAARNSGKAPdhIVRVVSTFGIGFPPFWLgLMLMIlfsvkldvlPVSGYGATfgdklahl 180
Cdd:COG1174   24 LLLVLLALLIALLIAVPLGILITRRRRLAG--LVLGVANILQTIPSLAL-LALLI---------PLLGIGPA-------- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820 181 ilPSLtVALSLSTVL--VRSLRAAmIESLKSDVATAARARGMPERIVFWRHVVPNSLvPTI-----NLLAVNIgwligGT 253
Cdd:COG1174   84 --PAI-IALVLYALLpiLRNTYTG-LRSVDPAVVEAARGMGMTPWQRLWRVELPLAL-PVIlagirTAAVQNI-----GT 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 499272820 254 VVVESVFALPGMGQLLVRAIFSRDY-MVVQGVAMVFACAtVLVNFIADIVTVAVDPR 309
Cdd:COG1174  154 ATLAALIGAGGLGDLIFDGLQLNNTaLILAGAILVALLA-LLVDLLLALLERLLTPR 209
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 16-242 7.92e-03

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 37.66  E-value: 7.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  16 PVIFGISIITFILVRLIPGDP-ARNLLGARATpsaiakiraqygldepmwqqyfyflknladgemGKSILYKIdvlkLIA 94
Cdd:PRK15021  97 PIRFGATSINFATDKPFPSPPsRQNWLGTDAN---------------------------------GGDVLARI----LYG 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499272820  95 TRVEPTIALVLSsvVLAVLIAVPMAALAARNSGKapdhivrvVSTFGIGFPPFWLG---LMLMILfsvkldvlpvsgyga 171
Cdd:PRK15021 140 TRISVLFGLMLT--LCSSVMGVLAGALQGYYGGK--------VDLWGQRFIEVWSGmptLFLIIL--------------- 194

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499272820 172 tfgdkLAHLILPSLTVALSLSTV-----LVRSLRAAMIESLKSDVATAARARGMPERIVFWRHVVPNSLVPTINLL 242
Cdd:PRK15021 195 -----LSSVVQPNFWWLLAITVLfgwmsLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFL 265
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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