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helicase-exonuclease AddAB subunit AddB [Listeria monocytogenes]
Protein Classification
helicase-exonuclease AddAB subunit AddB ( domain architecture ID 11494978 )
helicase-exonuclease AddAB subunit AddB is part of a heterodimer that acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease
List of domain hits
Name
Accession
Description
Interval
E-value
addB_Gpos
TIGR02773 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1157
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1724.19
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 1 M T L QI I A GRSGTGKTT HLMD E VGE KIK Q N S -- K TY I FI VPDQMTFQME TSF LN KEN L A GML GT Q IF SFSRLAW KI LQETG 78
Cdd:TIGR02773 1 M G L RF I Y GRSGTGKTT FIIN E IKQ KIK R N P fg K PI I LL VPDQMTFQME YAL LN DIE L N GML RA Q VL SFSRLAW RV LQETG 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 79 GL SK TFL SQ TG IE M V IRK AALDQ KD K LK IFSR A TSR KGF YSE L ANLFK E M K QE EV SI ED MVKS A TNLST S -- VNN K VH D I 156
Cdd:TIGR02773 81 GL TR TFL TS TG KQ M L IRK LIEEH KD E LK VYQK A SRK KGF TAQ L SEMIT E F K RY EV TP ED LRRM A ESITD S ey LKE K LE D L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 157 S L IYQ KY EE L LAD KF L EN EDYL R LLAEKI AD S DYLNQT EI V IDGF T SF SK QE LT VI GE LM R K CD KVT I SLTL NV P EI q HG 236
Cdd:TIGR02773 161 S I IYQ QF EE R LAD QY L DS EDYL T LLAEKI PQ S EDIKGA EI Y IDGF H SF TP QE YS VI EA LM K K AK KVT V SLTL DK P SK - RE 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 237 L DE Y S M F K A STEA YY A L LE LAK LN G TQ VEE NK F FLENKRA K TES LA F L ANTWGHNKFMSFKNEPQN L K I H QANNRRAE I E 316
Cdd:TIGR02773 240 P DE L S L F R A TSKT YY R L KQ LAK EL G ID VEE PI F LNTERPT K NKE LA H L EKQFDARPAIAYAEKQES L S I F QANNRRAE V E 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 317 G I AREI RQQALN - GYRY R DIAILTR NLG DY DV L CET V MEA Y N IP T FIDKKR A M AK HP F IEFIRSSLD A I LF NW K YE PI F Q 395
Cdd:TIGR02773 320 G V AREI LRLVRD k GYRY K DIAILTR DPE DY KD L VKA V FSD Y E IP Y FIDKKR S M LN HP L IEFIRSSLD V I QG NW R YE AV F R 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 396 AV KT EFF F DIT E KSSLN R RKA D I LENYVL EN GI QN K WK W E KE GDWI YR KI RGL STNV l P QTDEEI H MQ SII N EM R NL IV N 475
Cdd:TIGR02773 400 YL KT GLL F PLN E PFIDV R ELI D Q LENYVL AY GI KG K KR W W KE DWFQ YR RF RGL DDDF - A QTDEEI E MQ EML N DT R DW IV P 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 476 PL S T L E LNLR KAKT GM EFA L ALY HY LE QVNAVER LE SW RQRAE EQ G YL E L AREHEQAW SSISA LLDEFVEVLG E E TL DL D 555
Cdd:TIGR02773 479 PL F T F E KRMK KAKT VK EFA E ALY EF LE ELDLPDK LE KE RQRAE DD G RI E E AREHEQAW DAVIQ LLDEFVEVLG N E EM DL N 558
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 556 S F T E I I GT GL DA LEFSL L PP S LDQV VLSD M ENA K LLDM K V IF AI G M NDGV M P L R Q K DK GI F SD Q DR DA L RAEDSK L KPSA 635
Cdd:TIGR02773 559 L F Q E V I DI GL EQ LEFSL I PP A LDQV FVGT M DRS K MYNT K C IF LL G A NDGV L P A R P K EN GI L SD E DR EL L EQIGVE L SSTS 638
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 636 KNNIGE E DL L A Y KIISLP SD K L FL SYP A AD E EGK V L SE S NYLRKIKGQ F NE L N ES VY L TD P SLL SD A EQ S SY IRS K QA TL 715
Cdd:TIGR02773 639 REKLLD E QF L V Y TAFTSA SD R L KV SYP L AD A EGK S L RP S IIIHRLEEL F PK L K ES LL L NE P EQV SD E EQ L SY VSN K LP TL 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 716 GL LTSQL QMY KRGY TL S S VWWD A YN S Y F E NE K ESIMAKQ VLS S L Y Y E N K TK P LQE TT AK N L F GE T I H ASVSR M E KFFS C E 795
Cdd:TIGR02773 719 SE LTSQL RKW KRGY PI S D VWWD V YN W Y R E ED K WKQGLEY VLS G L F Y D N E TK Q LQE SK AK Q L Y GE R I Q ASVSR L E TYNA C P 798
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 796 F Q H Y AQYGLKL E ER GHFQ L Q A V D M G EI FH G A MEW IS A ELK RNN LDW GN LT E E E C KQM A KL A MTF LAPK I QHEILLSS K R M 875
Cdd:TIGR02773 799 F A H F AQYGLKL K ER KIYK L E A P D L G QL FH E A LKE IS D ELK EEK LDW SD LT K E Q C RLF A ND A VEN LAPK L QHEILLSS N R Y 878
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 876 E Y I Q Y KL LQ I I TRA TT VL N EQAK S S A F R PVGLE VD FG LKGD - I PPLK IP L QSDS EL L L Q GRIDR I D M AE QD D R T F LRIID 954
Cdd:TIGR02773 879 R Y V Q K KL KR I V TRA VG VL S EQAK R S G F V PVGLE LG FG FGKN p L PPLK LQ L KNGE EL E L R GRIDR V D K AE KE D E T Y LRIID 958
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 955 YKSSS HD L A LTEVYYGLALQMLTYLDIV V TN AQ K MI G KT A E PAGVLYFH M H NQYV QA EKE L SD E A I AK E LQ K SS KMKGL I 1034
Cdd:TIGR02773 959 YKSSS KG L D LTEVYYGLALQMLTYLDIV L TN SA K WL G NQ A T PAGVLYFH I H DPMI QA KGD L TE E E I EQ E IF K EY KMKGL L 1038
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 1035 LSD PVA V S LMD M TLE K G K a S T IIPA EI K QN G E L SA RS RT AT RA EF DKM R QF VR H K Y QEAG NK I L DG A VSI N PYK L K ER TP 1114
Cdd:TIGR02773 1039 LSD QEV V R LMD T TLE E G S - S N IIPA SL K KD G S L GS RS KA AT EE EF ELL R KH VR R K F QEAG EN I T DG R VSI E PYK M K KQ TP 1117
1130 1140 1150 1160
....*....|....*....|....*....|....*....|...
gi 499298987 1115 CQ F C S F R S F C G FD P SL TS N Q YRHL AN EK A ETIL TKMDI E G G TQ 1157
Cdd:TIGR02773 1118 CQ Y C N F S S V C Q FD T SL EE N E YRHL EA EK D ETIL EWINE E V G GN 1160
Name
Accession
Description
Interval
E-value
addB_Gpos
TIGR02773 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1157
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1724.19
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 1 M T L QI I A GRSGTGKTT HLMD E VGE KIK Q N S -- K TY I FI VPDQMTFQME TSF LN KEN L A GML GT Q IF SFSRLAW KI LQETG 78
Cdd:TIGR02773 1 M G L RF I Y GRSGTGKTT FIIN E IKQ KIK R N P fg K PI I LL VPDQMTFQME YAL LN DIE L N GML RA Q VL SFSRLAW RV LQETG 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 79 GL SK TFL SQ TG IE M V IRK AALDQ KD K LK IFSR A TSR KGF YSE L ANLFK E M K QE EV SI ED MVKS A TNLST S -- VNN K VH D I 156
Cdd:TIGR02773 81 GL TR TFL TS TG KQ M L IRK LIEEH KD E LK VYQK A SRK KGF TAQ L SEMIT E F K RY EV TP ED LRRM A ESITD S ey LKE K LE D L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 157 S L IYQ KY EE L LAD KF L EN EDYL R LLAEKI AD S DYLNQT EI V IDGF T SF SK QE LT VI GE LM R K CD KVT I SLTL NV P EI q HG 236
Cdd:TIGR02773 161 S I IYQ QF EE R LAD QY L DS EDYL T LLAEKI PQ S EDIKGA EI Y IDGF H SF TP QE YS VI EA LM K K AK KVT V SLTL DK P SK - RE 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 237 L DE Y S M F K A STEA YY A L LE LAK LN G TQ VEE NK F FLENKRA K TES LA F L ANTWGHNKFMSFKNEPQN L K I H QANNRRAE I E 316
Cdd:TIGR02773 240 P DE L S L F R A TSKT YY R L KQ LAK EL G ID VEE PI F LNTERPT K NKE LA H L EKQFDARPAIAYAEKQES L S I F QANNRRAE V E 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 317 G I AREI RQQALN - GYRY R DIAILTR NLG DY DV L CET V MEA Y N IP T FIDKKR A M AK HP F IEFIRSSLD A I LF NW K YE PI F Q 395
Cdd:TIGR02773 320 G V AREI LRLVRD k GYRY K DIAILTR DPE DY KD L VKA V FSD Y E IP Y FIDKKR S M LN HP L IEFIRSSLD V I QG NW R YE AV F R 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 396 AV KT EFF F DIT E KSSLN R RKA D I LENYVL EN GI QN K WK W E KE GDWI YR KI RGL STNV l P QTDEEI H MQ SII N EM R NL IV N 475
Cdd:TIGR02773 400 YL KT GLL F PLN E PFIDV R ELI D Q LENYVL AY GI KG K KR W W KE DWFQ YR RF RGL DDDF - A QTDEEI E MQ EML N DT R DW IV P 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 476 PL S T L E LNLR KAKT GM EFA L ALY HY LE QVNAVER LE SW RQRAE EQ G YL E L AREHEQAW SSISA LLDEFVEVLG E E TL DL D 555
Cdd:TIGR02773 479 PL F T F E KRMK KAKT VK EFA E ALY EF LE ELDLPDK LE KE RQRAE DD G RI E E AREHEQAW DAVIQ LLDEFVEVLG N E EM DL N 558
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 556 S F T E I I GT GL DA LEFSL L PP S LDQV VLSD M ENA K LLDM K V IF AI G M NDGV M P L R Q K DK GI F SD Q DR DA L RAEDSK L KPSA 635
Cdd:TIGR02773 559 L F Q E V I DI GL EQ LEFSL I PP A LDQV FVGT M DRS K MYNT K C IF LL G A NDGV L P A R P K EN GI L SD E DR EL L EQIGVE L SSTS 638
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 636 KNNIGE E DL L A Y KIISLP SD K L FL SYP A AD E EGK V L SE S NYLRKIKGQ F NE L N ES VY L TD P SLL SD A EQ S SY IRS K QA TL 715
Cdd:TIGR02773 639 REKLLD E QF L V Y TAFTSA SD R L KV SYP L AD A EGK S L RP S IIIHRLEEL F PK L K ES LL L NE P EQV SD E EQ L SY VSN K LP TL 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 716 GL LTSQL QMY KRGY TL S S VWWD A YN S Y F E NE K ESIMAKQ VLS S L Y Y E N K TK P LQE TT AK N L F GE T I H ASVSR M E KFFS C E 795
Cdd:TIGR02773 719 SE LTSQL RKW KRGY PI S D VWWD V YN W Y R E ED K WKQGLEY VLS G L F Y D N E TK Q LQE SK AK Q L Y GE R I Q ASVSR L E TYNA C P 798
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 796 F Q H Y AQYGLKL E ER GHFQ L Q A V D M G EI FH G A MEW IS A ELK RNN LDW GN LT E E E C KQM A KL A MTF LAPK I QHEILLSS K R M 875
Cdd:TIGR02773 799 F A H F AQYGLKL K ER KIYK L E A P D L G QL FH E A LKE IS D ELK EEK LDW SD LT K E Q C RLF A ND A VEN LAPK L QHEILLSS N R Y 878
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 876 E Y I Q Y KL LQ I I TRA TT VL N EQAK S S A F R PVGLE VD FG LKGD - I PPLK IP L QSDS EL L L Q GRIDR I D M AE QD D R T F LRIID 954
Cdd:TIGR02773 879 R Y V Q K KL KR I V TRA VG VL S EQAK R S G F V PVGLE LG FG FGKN p L PPLK LQ L KNGE EL E L R GRIDR V D K AE KE D E T Y LRIID 958
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 955 YKSSS HD L A LTEVYYGLALQMLTYLDIV V TN AQ K MI G KT A E PAGVLYFH M H NQYV QA EKE L SD E A I AK E LQ K SS KMKGL I 1034
Cdd:TIGR02773 959 YKSSS KG L D LTEVYYGLALQMLTYLDIV L TN SA K WL G NQ A T PAGVLYFH I H DPMI QA KGD L TE E E I EQ E IF K EY KMKGL L 1038
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 1035 LSD PVA V S LMD M TLE K G K a S T IIPA EI K QN G E L SA RS RT AT RA EF DKM R QF VR H K Y QEAG NK I L DG A VSI N PYK L K ER TP 1114
Cdd:TIGR02773 1039 LSD QEV V R LMD T TLE E G S - S N IIPA SL K KD G S L GS RS KA AT EE EF ELL R KH VR R K F QEAG EN I T DG R VSI E PYK M K KQ TP 1117
1130 1140 1150 1160
....*....|....*....|....*....|....*....|...
gi 499298987 1115 CQ F C S F R S F C G FD P SL TS N Q YRHL AN EK A ETIL TKMDI E G G TQ 1157
Cdd:TIGR02773 1118 CQ Y C N F S S V C Q FD T SL EE N E YRHL EA EK D ETIL EWINE E V G GN 1160
AddB
COG3857 ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
4-1143
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 1040.09
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 4 QI I A GR S G T GKTT H L MD E VG E KI K QNSK t Y I FI VP D QMTFQ M E TSF L NKEN L A G MLGT Q IF SFSRLAW KI LQETGG LSKT 83
Cdd:COG3857 1 RF I L GR A G S GKTT Y L LE E IK E EL K EGKP - I I LL VP E QMTFQ A E RAL L KRLG L G G SIRA Q VL SFSRLAW RV LQETGG ATRP 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 84 F LS QT G IE M VI RK AALDQ KD K LK I F S RA TSRK GF YSE LA N L FK E M K QEEVSI ED MVKS A TN L S tsvn N K VH D IS LIY QK Y 163
Cdd:COG3857 80 L LS DA G KR M LL RK ILEEH KD E LK V F A RA ADKP GF IEQ LA E L IT E L K RYGITP ED LEEA A EL L K ---- E K LR D LA LIY EA Y 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 164 EE L LA DKFLEN ED Y LRLLAEK IAD S DY L NQT EI V IDGFT S F SK QEL TVIGE L MR K CDK VTI S LTL NV peiqhgl DE YSM F 243
Cdd:COG3857 156 EE K LA GRYIDS ED L LRLLAEK LEK S EF L EGA EI Y IDGFT D F TP QEL ELLEA L LK K AKE VTI T LTL DP ------- DE LDL F 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 244 K A ST E A Y YA LLELAK L NG TQ VE E nkfflenkr A K TES LA F L ANTWGHN kfm SFKN EP QNLK I HQ A N NRRAE I E GI AREIR 323
Cdd:COG3857 229 S A TG E T Y ER LLELAK E NG VE VE F --------- K K SPE LA H L ERNLFAY --- PPEE EP EGIE I IE A A NRRAE V E AV AREIR 296
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 324 QQALN - GYRYRDIA ILT R N L GD Y DV L C E T V MEA Y N IP T FID K KR AMAK HP FI E F I R S S L DAILF N WK YE PI F QAV KT EFF 402
Cdd:COG3857 297 RLVRE e GYRYRDIA VVV R D L EA Y AP L I E R V FAE Y G IP Y FID E KR PLSH HP LV E L I L S L L ELVRS N FR YE DV F RLL KT GLL 376
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 403 FDIT ekssln R RKA D I LENYVL EN GI Q - NK W KWEKEGDW iyrkirglstnv LPQ TDEE IHMQSII NE M R NLIVN PL ST L E 481
Cdd:COG3857 377 RPLS ------ R EEI D R LENYVL AY GI R g RR W LERYLEEE ------------ EEL TDEE EEDLERL NE L R DRLLE PL LP L R 438
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 482 LN L R KAKT GM E F A L ALY HY LE QVNAV E R LE S WR Q r AEE Q G Y LE L AREHEQAW SSISA LLDE F VEVLG E E T L D L DS F TE I I 561
Cdd:COG3857 439 ER L K KAKT VR E W A E ALY EF LE ELGVP E K LE E WR E - AEE A G D LE E AREHEQAW NALIE LLDE L VEVLG D E K L S L EE F LR I L 517
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 562 GT GL DA L E F S L L PPSLDQV VLSDMEN A KL LD M K VI F AI G M N D GV M P L R QKDK G IF SD QD R DA L RAEDSK L K P SAKNNIG E 641
Cdd:COG3857 518 ES GL EE L T F G L I PPSLDQV QVGGLDR A RG LD F K AV F VL G L N E GV F P A R PRED G LL SD EE R ER L NELGLE L P P TSRERLL E 597
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 642 E DL L A Y KIISLP S DK L F LSYP A ADEEGK V L SE S NYLRKIKGQ F N EL N E SVY L tdpsllsd A E QSS YI RSKQAT L GL L TSQ 721
Cdd:COG3857 598 E RF L F Y RALTRA S ER L Y LSYP L ADEEGK A L LP S PLIDRLREL F P EL E E RSL L -------- E E ELE YI GTPESA L SE L AAA 669
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 722 L qmyk R GYT L SSV WWD A Y NSY fenekesimakqvlsslyyenktkplqettaknlfget IHA SVSR M E KFFS C E FQ HYAQ 801
Cdd:COG3857 670 L ---- R QLE L APL WWD V Y KWL -------------------------------------- LKL SVSR L E TYAA C P FQ FFLR 707
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 802 YGLKL E ER GHFQ L Q A V D M G EI FH GAM E WISA ELK RNN LDW GN L TE EE CKQMAKL A MTF LAP KI Q HE ILLSS K R ME Y IQYK 881
Cdd:COG3857 708 YGLKL K ER EEYE L D A P D R G TL FH AVL E RFYK ELK EEG LDW AD L SD EE LEELLEE A VEE LAP EL Q NG ILLSS A R YR Y LLER 787
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 882 L LQIIT RA TTV L N E Q A KS S A F R PV G LE VD FG LK G DI PPL KIP L QSDSELL L Q GRIDRID MA E Q D D R t F LRIIDYKS S S HD 961
Cdd:COG3857 788 L KRLLK RA RRW L E E E A RR S G F E PV A LE LS FG PE G GL PPL ELE L PNGRKIR L R GRIDRID RL E S D G R - Y LRIIDYKS G S KK 866
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 962 LA L TE VYYGLALQ MLT YLD IVVT N AQ kmi GK T AEPAG V LYFH MH N QYVQ A E K E L sdeaiakelq K SS KMKGL I L S DP VAV 1041
Cdd:COG3857 867 FD L DD VYYGLALQ LPL YLD AALE N LE --- GK E AEPAG A LYFH LK N PKLK A K K P L ---------- K KL KMKGL L L D DP EVL 933
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 1042 S lmdmtlekgkast IIP ae I K QN G ELS a R S RTATRA EF DKMRQF VR HKYQ EAG NK IL D G AVS INPY KL K E RT P CQ F C SFR 1121
Cdd:COG3857 934 E ------------- IIP -- L K KD G SFK - N S KVLSEE EF EELLDH VR ELLK EAG EE IL A G DFA INPY RT K D RT A CQ Y C PYK 997
1130 1140
....*....|....*....|..
gi 499298987 1122 S F C G FD P SL TS N Q YR H L ANEKA 1143
Cdd:COG3857 998 S I C R FD E SL EG N E YR K L KKKEG 1019
PDDEXK_1
pfam12705 PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
782-1124
1.40e-37
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily
Pssm-ID: 432731 [Multi-domain]
Cd Length: 250
Bit Score: 141.90
E-value: 1.40e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 782 HA S V SR M E KFFS C EFQHYAQ Y G L K L ee R GHFQ L Q A V D M G EIF H G A M E WIS aelkrnnl D WG N L T EE ECKQMAKLAMTF L A 861
Cdd:pfam12705 1 RL S P SR L E TYLT C PLRFFLR Y L L G L -- R EDEE L D A P D L G TLV H A A L E RFY -------- R WG R L P EE DLEELLQALLEE L W 70
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 862 P KI -- Q H EIL lss K R MEYIQYK L LQIIT R ATTV L N E Q - AKSSA FRPV GL E VD FG lkgdipplkiplqs DSELL L Q GRIDR 938
Cdd:pfam12705 71 P EL gl Q S EIL --- P R LPWLAGR L RRRLE R MLRR L A E W l RARRG FRPV AV E LG FG -------------- GTTVR L V GRIDR 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 939 I D mae Q D DRTF LRIIDYK SS S H --- DLA L t EV Y Y G la LQ M L T YL DIVVTNAQKMI G ktae PAG V LY FHMHNQYVQA E KEL 1015
Cdd:pfam12705 134 V D --- L D GEGY LRIIDYK TG S A ppq SED L - DL Y E G -- LQ L L L YL LALAAGEKALG G ---- PAG A LY LRLDDPLKKD E EVV 203
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 1016 sdeaiakelqksskmkglilsdpvavslmdmtlekgkastiipaeikqngelsa RSRTA T RA EFD KMR Q FV R hkyq E AGN 1095
Cdd:pfam12705 204 ------------------------------------------------------ EPMVL T ED EFD ALL Q EL R ---- E LAE 225
330 340
....*....|....*....|....*....
gi 499298987 1096 K IL D G AVSIN P Y K L kertp C QF C SF RS F C 1124
Cdd:pfam12705 226 E IL A G EFPAR P G K K ----- C RY C PY RS I C 249
Name
Accession
Description
Interval
E-value
addB_Gpos
TIGR02773 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1157
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1724.19
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 1 M T L QI I A GRSGTGKTT HLMD E VGE KIK Q N S -- K TY I FI VPDQMTFQME TSF LN KEN L A GML GT Q IF SFSRLAW KI LQETG 78
Cdd:TIGR02773 1 M G L RF I Y GRSGTGKTT FIIN E IKQ KIK R N P fg K PI I LL VPDQMTFQME YAL LN DIE L N GML RA Q VL SFSRLAW RV LQETG 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 79 GL SK TFL SQ TG IE M V IRK AALDQ KD K LK IFSR A TSR KGF YSE L ANLFK E M K QE EV SI ED MVKS A TNLST S -- VNN K VH D I 156
Cdd:TIGR02773 81 GL TR TFL TS TG KQ M L IRK LIEEH KD E LK VYQK A SRK KGF TAQ L SEMIT E F K RY EV TP ED LRRM A ESITD S ey LKE K LE D L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 157 S L IYQ KY EE L LAD KF L EN EDYL R LLAEKI AD S DYLNQT EI V IDGF T SF SK QE LT VI GE LM R K CD KVT I SLTL NV P EI q HG 236
Cdd:TIGR02773 161 S I IYQ QF EE R LAD QY L DS EDYL T LLAEKI PQ S EDIKGA EI Y IDGF H SF TP QE YS VI EA LM K K AK KVT V SLTL DK P SK - RE 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 237 L DE Y S M F K A STEA YY A L LE LAK LN G TQ VEE NK F FLENKRA K TES LA F L ANTWGHNKFMSFKNEPQN L K I H QANNRRAE I E 316
Cdd:TIGR02773 240 P DE L S L F R A TSKT YY R L KQ LAK EL G ID VEE PI F LNTERPT K NKE LA H L EKQFDARPAIAYAEKQES L S I F QANNRRAE V E 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 317 G I AREI RQQALN - GYRY R DIAILTR NLG DY DV L CET V MEA Y N IP T FIDKKR A M AK HP F IEFIRSSLD A I LF NW K YE PI F Q 395
Cdd:TIGR02773 320 G V AREI LRLVRD k GYRY K DIAILTR DPE DY KD L VKA V FSD Y E IP Y FIDKKR S M LN HP L IEFIRSSLD V I QG NW R YE AV F R 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 396 AV KT EFF F DIT E KSSLN R RKA D I LENYVL EN GI QN K WK W E KE GDWI YR KI RGL STNV l P QTDEEI H MQ SII N EM R NL IV N 475
Cdd:TIGR02773 400 YL KT GLL F PLN E PFIDV R ELI D Q LENYVL AY GI KG K KR W W KE DWFQ YR RF RGL DDDF - A QTDEEI E MQ EML N DT R DW IV P 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 476 PL S T L E LNLR KAKT GM EFA L ALY HY LE QVNAVER LE SW RQRAE EQ G YL E L AREHEQAW SSISA LLDEFVEVLG E E TL DL D 555
Cdd:TIGR02773 479 PL F T F E KRMK KAKT VK EFA E ALY EF LE ELDLPDK LE KE RQRAE DD G RI E E AREHEQAW DAVIQ LLDEFVEVLG N E EM DL N 558
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 556 S F T E I I GT GL DA LEFSL L PP S LDQV VLSD M ENA K LLDM K V IF AI G M NDGV M P L R Q K DK GI F SD Q DR DA L RAEDSK L KPSA 635
Cdd:TIGR02773 559 L F Q E V I DI GL EQ LEFSL I PP A LDQV FVGT M DRS K MYNT K C IF LL G A NDGV L P A R P K EN GI L SD E DR EL L EQIGVE L SSTS 638
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 636 KNNIGE E DL L A Y KIISLP SD K L FL SYP A AD E EGK V L SE S NYLRKIKGQ F NE L N ES VY L TD P SLL SD A EQ S SY IRS K QA TL 715
Cdd:TIGR02773 639 REKLLD E QF L V Y TAFTSA SD R L KV SYP L AD A EGK S L RP S IIIHRLEEL F PK L K ES LL L NE P EQV SD E EQ L SY VSN K LP TL 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 716 GL LTSQL QMY KRGY TL S S VWWD A YN S Y F E NE K ESIMAKQ VLS S L Y Y E N K TK P LQE TT AK N L F GE T I H ASVSR M E KFFS C E 795
Cdd:TIGR02773 719 SE LTSQL RKW KRGY PI S D VWWD V YN W Y R E ED K WKQGLEY VLS G L F Y D N E TK Q LQE SK AK Q L Y GE R I Q ASVSR L E TYNA C P 798
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 796 F Q H Y AQYGLKL E ER GHFQ L Q A V D M G EI FH G A MEW IS A ELK RNN LDW GN LT E E E C KQM A KL A MTF LAPK I QHEILLSS K R M 875
Cdd:TIGR02773 799 F A H F AQYGLKL K ER KIYK L E A P D L G QL FH E A LKE IS D ELK EEK LDW SD LT K E Q C RLF A ND A VEN LAPK L QHEILLSS N R Y 878
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 876 E Y I Q Y KL LQ I I TRA TT VL N EQAK S S A F R PVGLE VD FG LKGD - I PPLK IP L QSDS EL L L Q GRIDR I D M AE QD D R T F LRIID 954
Cdd:TIGR02773 879 R Y V Q K KL KR I V TRA VG VL S EQAK R S G F V PVGLE LG FG FGKN p L PPLK LQ L KNGE EL E L R GRIDR V D K AE KE D E T Y LRIID 958
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 955 YKSSS HD L A LTEVYYGLALQMLTYLDIV V TN AQ K MI G KT A E PAGVLYFH M H NQYV QA EKE L SD E A I AK E LQ K SS KMKGL I 1034
Cdd:TIGR02773 959 YKSSS KG L D LTEVYYGLALQMLTYLDIV L TN SA K WL G NQ A T PAGVLYFH I H DPMI QA KGD L TE E E I EQ E IF K EY KMKGL L 1038
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 1035 LSD PVA V S LMD M TLE K G K a S T IIPA EI K QN G E L SA RS RT AT RA EF DKM R QF VR H K Y QEAG NK I L DG A VSI N PYK L K ER TP 1114
Cdd:TIGR02773 1039 LSD QEV V R LMD T TLE E G S - S N IIPA SL K KD G S L GS RS KA AT EE EF ELL R KH VR R K F QEAG EN I T DG R VSI E PYK M K KQ TP 1117
1130 1140 1150 1160
....*....|....*....|....*....|....*....|...
gi 499298987 1115 CQ F C S F R S F C G FD P SL TS N Q YRHL AN EK A ETIL TKMDI E G G TQ 1157
Cdd:TIGR02773 1118 CQ Y C N F S S V C Q FD T SL EE N E YRHL EA EK D ETIL EWINE E V G GN 1160
AddB
COG3857 ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
4-1143
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 1040.09
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 4 QI I A GR S G T GKTT H L MD E VG E KI K QNSK t Y I FI VP D QMTFQ M E TSF L NKEN L A G MLGT Q IF SFSRLAW KI LQETGG LSKT 83
Cdd:COG3857 1 RF I L GR A G S GKTT Y L LE E IK E EL K EGKP - I I LL VP E QMTFQ A E RAL L KRLG L G G SIRA Q VL SFSRLAW RV LQETGG ATRP 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 84 F LS QT G IE M VI RK AALDQ KD K LK I F S RA TSRK GF YSE LA N L FK E M K QEEVSI ED MVKS A TN L S tsvn N K VH D IS LIY QK Y 163
Cdd:COG3857 80 L LS DA G KR M LL RK ILEEH KD E LK V F A RA ADKP GF IEQ LA E L IT E L K RYGITP ED LEEA A EL L K ---- E K LR D LA LIY EA Y 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 164 EE L LA DKFLEN ED Y LRLLAEK IAD S DY L NQT EI V IDGFT S F SK QEL TVIGE L MR K CDK VTI S LTL NV peiqhgl DE YSM F 243
Cdd:COG3857 156 EE K LA GRYIDS ED L LRLLAEK LEK S EF L EGA EI Y IDGFT D F TP QEL ELLEA L LK K AKE VTI T LTL DP ------- DE LDL F 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 244 K A ST E A Y YA LLELAK L NG TQ VE E nkfflenkr A K TES LA F L ANTWGHN kfm SFKN EP QNLK I HQ A N NRRAE I E GI AREIR 323
Cdd:COG3857 229 S A TG E T Y ER LLELAK E NG VE VE F --------- K K SPE LA H L ERNLFAY --- PPEE EP EGIE I IE A A NRRAE V E AV AREIR 296
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 324 QQALN - GYRYRDIA ILT R N L GD Y DV L C E T V MEA Y N IP T FID K KR AMAK HP FI E F I R S S L DAILF N WK YE PI F QAV KT EFF 402
Cdd:COG3857 297 RLVRE e GYRYRDIA VVV R D L EA Y AP L I E R V FAE Y G IP Y FID E KR PLSH HP LV E L I L S L L ELVRS N FR YE DV F RLL KT GLL 376
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 403 FDIT ekssln R RKA D I LENYVL EN GI Q - NK W KWEKEGDW iyrkirglstnv LPQ TDEE IHMQSII NE M R NLIVN PL ST L E 481
Cdd:COG3857 377 RPLS ------ R EEI D R LENYVL AY GI R g RR W LERYLEEE ------------ EEL TDEE EEDLERL NE L R DRLLE PL LP L R 438
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 482 LN L R KAKT GM E F A L ALY HY LE QVNAV E R LE S WR Q r AEE Q G Y LE L AREHEQAW SSISA LLDE F VEVLG E E T L D L DS F TE I I 561
Cdd:COG3857 439 ER L K KAKT VR E W A E ALY EF LE ELGVP E K LE E WR E - AEE A G D LE E AREHEQAW NALIE LLDE L VEVLG D E K L S L EE F LR I L 517
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 562 GT GL DA L E F S L L PPSLDQV VLSDMEN A KL LD M K VI F AI G M N D GV M P L R QKDK G IF SD QD R DA L RAEDSK L K P SAKNNIG E 641
Cdd:COG3857 518 ES GL EE L T F G L I PPSLDQV QVGGLDR A RG LD F K AV F VL G L N E GV F P A R PRED G LL SD EE R ER L NELGLE L P P TSRERLL E 597
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 642 E DL L A Y KIISLP S DK L F LSYP A ADEEGK V L SE S NYLRKIKGQ F N EL N E SVY L tdpsllsd A E QSS YI RSKQAT L GL L TSQ 721
Cdd:COG3857 598 E RF L F Y RALTRA S ER L Y LSYP L ADEEGK A L LP S PLIDRLREL F P EL E E RSL L -------- E E ELE YI GTPESA L SE L AAA 669
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 722 L qmyk R GYT L SSV WWD A Y NSY fenekesimakqvlsslyyenktkplqettaknlfget IHA SVSR M E KFFS C E FQ HYAQ 801
Cdd:COG3857 670 L ---- R QLE L APL WWD V Y KWL -------------------------------------- LKL SVSR L E TYAA C P FQ FFLR 707
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 802 YGLKL E ER GHFQ L Q A V D M G EI FH GAM E WISA ELK RNN LDW GN L TE EE CKQMAKL A MTF LAP KI Q HE ILLSS K R ME Y IQYK 881
Cdd:COG3857 708 YGLKL K ER EEYE L D A P D R G TL FH AVL E RFYK ELK EEG LDW AD L SD EE LEELLEE A VEE LAP EL Q NG ILLSS A R YR Y LLER 787
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 882 L LQIIT RA TTV L N E Q A KS S A F R PV G LE VD FG LK G DI PPL KIP L QSDSELL L Q GRIDRID MA E Q D D R t F LRIIDYKS S S HD 961
Cdd:COG3857 788 L KRLLK RA RRW L E E E A RR S G F E PV A LE LS FG PE G GL PPL ELE L PNGRKIR L R GRIDRID RL E S D G R - Y LRIIDYKS G S KK 866
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 962 LA L TE VYYGLALQ MLT YLD IVVT N AQ kmi GK T AEPAG V LYFH MH N QYVQ A E K E L sdeaiakelq K SS KMKGL I L S DP VAV 1041
Cdd:COG3857 867 FD L DD VYYGLALQ LPL YLD AALE N LE --- GK E AEPAG A LYFH LK N PKLK A K K P L ---------- K KL KMKGL L L D DP EVL 933
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 1042 S lmdmtlekgkast IIP ae I K QN G ELS a R S RTATRA EF DKMRQF VR HKYQ EAG NK IL D G AVS INPY KL K E RT P CQ F C SFR 1121
Cdd:COG3857 934 E ------------- IIP -- L K KD G SFK - N S KVLSEE EF EELLDH VR ELLK EAG EE IL A G DFA INPY RT K D RT A CQ Y C PYK 997
1130 1140
....*....|....*....|..
gi 499298987 1122 S F C G FD P SL TS N Q YR H L ANEKA 1143
Cdd:COG3857 998 S I C R FD E SL EG N E YR K L KKKEG 1019
PDDEXK_1
pfam12705 PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
782-1124
1.40e-37
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily
Pssm-ID: 432731 [Multi-domain]
Cd Length: 250
Bit Score: 141.90
E-value: 1.40e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 782 HA S V SR M E KFFS C EFQHYAQ Y G L K L ee R GHFQ L Q A V D M G EIF H G A M E WIS aelkrnnl D WG N L T EE ECKQMAKLAMTF L A 861
Cdd:pfam12705 1 RL S P SR L E TYLT C PLRFFLR Y L L G L -- R EDEE L D A P D L G TLV H A A L E RFY -------- R WG R L P EE DLEELLQALLEE L W 70
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 862 P KI -- Q H EIL lss K R MEYIQYK L LQIIT R ATTV L N E Q - AKSSA FRPV GL E VD FG lkgdipplkiplqs DSELL L Q GRIDR 938
Cdd:pfam12705 71 P EL gl Q S EIL --- P R LPWLAGR L RRRLE R MLRR L A E W l RARRG FRPV AV E LG FG -------------- GTTVR L V GRIDR 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 939 I D mae Q D DRTF LRIIDYK SS S H --- DLA L t EV Y Y G la LQ M L T YL DIVVTNAQKMI G ktae PAG V LY FHMHNQYVQA E KEL 1015
Cdd:pfam12705 134 V D --- L D GEGY LRIIDYK TG S A ppq SED L - DL Y E G -- LQ L L L YL LALAAGEKALG G ---- PAG A LY LRLDDPLKKD E EVV 203
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 1016 sdeaiakelqksskmkglilsdpvavslmdmtlekgkastiipaeikqngelsa RSRTA T RA EFD KMR Q FV R hkyq E AGN 1095
Cdd:pfam12705 204 ------------------------------------------------------ EPMVL T ED EFD ALL Q EL R ---- E LAE 225
330 340
....*....|....*....|....*....
gi 499298987 1096 K IL D G AVSIN P Y K L kertp C QF C SF RS F C 1124
Cdd:pfam12705 226 E IL A G EFPAR P G K K ----- C RY C PY RS I C 249
Slr0479
COG2887 RecB family exonuclease [Replication, recombination and repair];
784-978
1.01e-12
RecB family exonuclease [Replication, recombination and repair];
Pssm-ID: 442133 [Multi-domain]
Cd Length: 248
Bit Score: 69.30
E-value: 1.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 784 S V SR M E KFFS C EFQH YA Q Y G L K L EERGHFQLQ A V D M G EIF H GAM E WISAELK rnnldw GN L TE EE ckq MAK L AMTFL A pk 863
Cdd:COG2887 4 S P SR I E TLLR C PLRY YA R Y I L G L RDPLEPPPD A A D R G TLV H AVL E RFYKLPA ------ DE L PA EE --- LLA L LEEAW A -- 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 864 iqh E ILLSSKRMEYIQYKLLQIITR A tt V L NEQAKSSAFR PV GL EV D F G L kg DI P P lkiplqsds ELL L Q GRIDRID MAE 943
Cdd:COG2887 73 --- E LGFEDPWAAALWLERAERLLE A -- F L EWERAPAGLE PV AV EV E F E L -- EL P G --------- GVR L R GRIDRID RLP 136
170 180 190
....*....|....*....|....*....|....*
gi 499298987 944 q D D R tf L RII DYK SSSHDLALT E V yy G LAL Q MLT Y 978
Cdd:COG2887 137 - D G R -- L VVV DYK TGKAPSTKD E A -- G EDP Q LAL Y 166
UvrD
COG0210 Superfamily I DNA or RNA helicase [Replication, recombination and repair];
3-663
1.39e-06
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain]
Cd Length: 721
Bit Score: 52.63
E-value: 1.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 3 L QII AG r S G T GKT T ------- H L MD E V G ekikqnsktyif IV P D Q M --- TF ------ Q M etsfln K E NLAGM LG TQ ---- 62
Cdd:COG0210 22 L LVL AG - A G S GKT R vlthria Y L IA E G G ------------ VD P E Q I lav TF tnkaar E M ------ R E RIEAL LG RL argl 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 63 - IFS F SR LA WK IL Q --- E TG GL SKT F L ------ SQTG I EMVIRKAA LD Q K dklkifsratsr KGFYS EL AN L FKEM K Q E E 132
Cdd:COG0210 83 w VGT F HS LA LR IL R rha E LL GL PPN F T ildgdd QLRL I KELLKELG LD E K ------------ RFPPR EL LS L ISRA K N E G 150
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 133 VSI E DMVKSA tnlst SVNNKVHDISLI Y QK Y E E L L ADK --------------- FL EN EDY L RLLAEKIA -------- D SD 189
Cdd:COG0210 151 LTP E ELAELL ----- AADPEWRAAAEL Y EA Y Q E R L RAN naldfddllllavrl LE EN PEV L EKYQNRFR yilvdeyq D TN 225
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 190 YL n Q T E IV -- ID G ftsf SKQE L T V I G ------------------ ELMRKCDKV - T I S L TL N vpeiqhglde Y smfk A ST E 248
Cdd:COG0210 226 PA - Q Y E LL rl LA G ---- DGRN L C V V G dddqsiygfrgadpenil RFEKDFPDA k V I K L EQ N ---------- Y ---- R ST Q 286
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 249 A yya L L EL A klngtqvee N KFFLE N KRAKTES L aflant W GH N K fmsfkn E PQNLKIHQ A NNRRA E IEGI A R EIR QQALN 328
Cdd:COG0210 287 N --- I L DA A --------- N AVIAN N PGRLGKN L ------ W TD N G ------ E GEKVRLYV A PDEEE E ARFV A D EIR ELHEE 342
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 329 G YRYR DIA I L T R NLGDYDV L c E TVMEAYN IP ------- T F IDK --- K RAM A khp FIEFIRSSL D AIL fnwkyepi FQAVK 398
Cdd:COG0210 343 G VPLS DIA V L Y R TNAQSRA L - E EALRRAG IP yrvvggl R F YER aei K DLL A --- YLRLLANPD D DVA -------- LLRIL 410
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 399 TEFFFD I TEKS slnrrk ADI L ENYVL E N GI qnkwkwekegdwiyrkirglstnvlpqtdeeihmqsiin EMRNLIVNPLS 478
Cdd:COG0210 411 NVPRRG I GAAT ------ LER L REAAR E E GI --------------------------------------- SLLEALRDLGE 445
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 479 TLE L NL R K AK TGME FA --- L AL YHYL E QVNAV E R LE SWRQRA eeq GY L E -- LAREH E Q A WSSISA l L D E F V EVLGE ---- 549
Cdd:COG0210 446 LAG L SG R A AK ALRR FA ell E AL RAAA E RLPLE E L LE ALLDES --- GY E E el REEAG E E A ERRLEN - L E E L V DAAAR feer 521
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 550 - ETLD L DS F T E II -- GTG LDA LE fsllp PSL D Q V V L SDMEN AK L L DMK V I F AI G MND G VM P LRQ kdkgif S DQ D RDA L R a 626
Cdd:COG0210 522 n PGAS L EA F L E EL al LSD LDA AD ----- EDE D A V T L MTLHA AK G L EFP V V F LV G LEE G LF P HQR ------ S LD D EEE L E - 589
730 740 750
....*....|....*....|....*....|....*..
gi 499298987 627 edsklkpsaknnig EE DL L A Y KI I SLPSDK L F L S Y P A 663
Cdd:COG0210 590 -------------- EE RR L F Y VA I TRARER L Y L T Y A A 612
RecB
COG1074 3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ...
311-402
8.14e-05
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain]
Cd Length: 866
Bit Score: 46.88
E-value: 8.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 311 R RA E IEGI A RE IR Q --------- QALNGY R YR DIA I L T R NLGDYDVL c ETVME A YN IP TFIDKKRAMAKH P FIEFIRSS L 381
Cdd:COG1074 418 R ER E ARAV A AR IR R llaegttve GGGRPV R PG DIA V L V R TRSEAAAI - ARALK A AG IP VAASDRLSLFES P EVRDLLAL L 496
90 100
....*....|....*....|.
gi 499298987 382 D A I L FNWKYEPIFQAVKTEF F 402
Cdd:COG1074 497 R A L L NPEDDLALAAVLRSPL F 517
UvrD_C
pfam13361 UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ...
301-661
3.34e-04
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain]
Cd Length: 377
Bit Score: 44.32
E-value: 3.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 301 QNL KI HQ A NNRRA E I E G IA R EI RQQALNGYR Y R DIA I LTR NLG D Y D VL c E TVMEAYN IP T F IDK ---------- K RAM A - 369
Cdd:pfam13361 44 EKI KI IE A ETEEE E A E W IA L EI KKLVARDEK Y N DIA V LTR SNS D A D LI - E EALKKLG IP Y F VVG qtkffrreei K DIL A y 122
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 370 ------ KH PF I EFI R SSLDAILF -- N WKY E P I FQAV K TEFFFDITEKSSLNRRKADILENYVLE N GI qn KWKW E KE G - D W 440
Cdd:pfam13361 123 lrlian KH DS I SLK R ILNGPKRG ig N ATL E R I REYK K RGLRLSDFINPDTLTYGDPFVIALEQD N IV -- VFDV E TT G l D T 200
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 441 IYRK I RGLSTNV L PQTDE ----- E IHMQSIINEMRN L I V NPL S TLE L nlrk AKT G MEF A L AL YHY LE QVNAVER L E S W rq 515
Cdd:pfam13361 201 TEDE I IQIAAIK L NKKGV viesf E RFLRLKKPVGDS L Q V HGF S DEF L ---- QEN G ETP A E AL RDF LE KLENLRE L Y S I -- 274
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 516 raeeqgylel A RE heqawssisal L D EFV E VLGE E T l D L DS F T EI IGTGLDA LE F S LL pps LDQVVLSDMEN AK L L DMKV 595
Cdd:pfam13361 275 ---------- L RE ----------- Y D DIE E TPEP E D - A L RN F L EI ATLSNSE LE G S DI --- KERIPIMTIHQ AK G L EFDT 329
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499298987 596 I F AI G MND G VM P lrqkdkgifsdqdrd AL R AEDS klkpsa KN N IG EE DL L A Y KI I SLPSDK L FL SY 661
Cdd:pfam13361 330 V F LA G LEE G IF P --------------- SY R SIKD ------ EG N LE EE RR L F Y VA I TRAKKR L YI SY 374
RecB
COG1074 3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ...
820-1003
3.60e-04
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain]
Cd Length: 866
Bit Score: 44.95
E-value: 3.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 820 G EIF H GAM E WIS ------- AELKRNN L DW G N L T EEE CKQM A KLAMT FL apki QHE illsskrmeyiqyk LL QIITR A TT V 892
Cdd:COG1074 715 G TLV H RLL E HLD fsapael RAALARL L AR G G L D EEE AEAL A EALLA FL ---- ATP -------------- LL AELFA A AE V 776
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 893 L N E QA kssa F rp VGLEVDF GL K G dipplkiplqsdsel LL Q GRID RI dm A E Q D D R tf LR I I DYK SSSH --- D LALTEVY Y 969
Cdd:COG1074 777 L R E VP ---- F -- LLPDLYR GL G G --------------- LL K GRID LV -- F E D D G R -- VY I V DYK TNRL gpd D EEYLPER Y 831
170 180 190
....*....|....*....|....*....|....
gi 499298987 970 gl A LQ MLT Y LDIV vtna QKMIGKTAEP AG VLYFH 1003
Cdd:COG1074 832 -- R LQ LAL Y ALAL ---- ERLLPGRPVR AG LYFTD 859
TIGR03623
TIGR03623 probable DNA repair protein; Members of this protein family are bacterial proteins of about ...
793-957
1.96e-03
probable DNA repair protein; Members of this protein family are bacterial proteins of about 900 amino acids in length. Members show extended homology to proteins in TIGR02786, the AddB protein of double-strand break repair via homologous recombination. Members of this family, therefore, may be DNA repair proteins.
Pssm-ID: 274682 [Multi-domain]
Cd Length: 874
Bit Score: 42.34
E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 793 S C E F QHY AQ YG L KLE -- E RGHFQ L Q A VDM G EIF H GAM E WISAE LK rnnl DWGN L teeec KQMAKLAM - TFL A PK I QHEIL 869
Cdd:TIGR03623 608 A C P F RAF AQ HR L GAR al E EPVDG L D A LER G TLV H RVL E LFWER LK ---- NQEA L ----- NALDEAEL e QLI A EA I EEALA 678
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499298987 870 - LSSKRMEYIQYKL L QIIT - R ATTV L N E ---- QA K SSA F RP V GL E VDFGLK gd I PP L K iplqsdsell L QG RIDRID MAE 943
Cdd:TIGR03623 679 e ERARHSQTFPERF L ELEQ e R LLQL L L E wlel ER K RPP F EV V AT E QNHSIE -- I GG L E ---------- L KL RIDRID RLA 746
170
....*....|....
gi 499298987 944 q D DRTF lr IIDYK S 957
Cdd:TIGR03623 747 - D GSRL -- IIDYK T 757
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
