NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|499323051|ref|WP_011013543|]
View 

alpha/beta fold hydrolase [Corynebacterium glutamicum]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 50-207 9.93e-34

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 123.57  E-value: 9.93e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  50 THDHVSVRGIRLHLAEAGsPTKPLVLLIHGAFGGWYDYREVIGPLADaGFHVAAIDLRGYGMSDKPPTGYDLRHAAGELS 129
Cdd:COG0596    3 TPRFVTVDGVRLHYREAG-PDGPPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAGGYTLDDLADDLA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499323051 130 SVIAALGHDDALLVGSDTGASIAWAIASMYPERVRGLISLGAIHPLdMRRAIRRKPHLHVSDLSRLAPFRLPSFLHNL 207
Cdd:COG0596   81 ALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVLAA-LAEPLRRPGLAPEALAALLRALARTDLRERL 157
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 50-207 9.93e-34

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 123.57  E-value: 9.93e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  50 THDHVSVRGIRLHLAEAGsPTKPLVLLIHGAFGGWYDYREVIGPLADaGFHVAAIDLRGYGMSDKPPTGYDLRHAAGELS 129
Cdd:COG0596    3 TPRFVTVDGVRLHYREAG-PDGPPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAGGYTLDDLADDLA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499323051 130 SVIAALGHDDALLVGSDTGASIAWAIASMYPERVRGLISLGAIHPLdMRRAIRRKPHLHVSDLSRLAPFRLPSFLHNL 207
Cdd:COG0596   81 ALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVLAA-LAEPLRRPGLAPEALAALLRALARTDLRERL 157
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 72-174 4.02e-21

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 90.64  E-value: 4.02e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051   72 PLVLLIHGAFGGWYDYREVIGPLADAGFHVAAIDLRGYGMSDKPP--TGYDLRHAAGELSSVIAALGHDDALLVGSDTGA 149
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKaqDDYRTDDLAEDLEYILEALGLEKVNLVGHSMGG 80

                          90       100
                  ....*....|....*....|....*
gi 499323051  150 SIAWAIASMYPERVRGLISLGAIHP 174
Cdd:pfam00561  81 LIALAYAAKYPDRVKALVLLGALDP 105
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 43-166 5.75e-16

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 76.96  E-value: 5.75e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  43 IALDGPFTHDHVSVRGIRLHLAEAGSptKPLVLLIHGAFGGWYDYREVIGPLADAGfHVAAIDLRGYGMSDKPPTGYDLR 122
Cdd:PRK03592   1 FGVEPPGEMRRVEVLGSRMAYIETGE--GDPIVFLHGNPTSSYLWRNIIPHLAGLG-RCLAPDLIGMGASDKPDIDYTFA 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 499323051 123 HAAGELSSVIAALGHDDALLVGSDTGASIAWAIASMYPERVRGL 166
Cdd:PRK03592  78 DHARYLDAWFDALGLDDVVLVGHDWGSALGFDWAARHPDRVRGI 121
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 50-207 9.93e-34

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 123.57  E-value: 9.93e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  50 THDHVSVRGIRLHLAEAGsPTKPLVLLIHGAFGGWYDYREVIGPLADaGFHVAAIDLRGYGMSDKPPTGYDLRHAAGELS 129
Cdd:COG0596    3 TPRFVTVDGVRLHYREAG-PDGPPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGRSDKPAGGYTLDDLADDLA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499323051 130 SVIAALGHDDALLVGSDTGASIAWAIASMYPERVRGLISLGAIHPLdMRRAIRRKPHLHVSDLSRLAPFRLPSFLHNL 207
Cdd:COG0596   81 ALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVLAA-LAEPLRRPGLAPEALAALLRALARTDLRERL 157
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 72-174 4.02e-21

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 90.64  E-value: 4.02e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051   72 PLVLLIHGAFGGWYDYREVIGPLADAGFHVAAIDLRGYGMSDKPP--TGYDLRHAAGELSSVIAALGHDDALLVGSDTGA 149
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKaqDDYRTDDLAEDLEYILEALGLEKVNLVGHSMGG 80

                          90       100
                  ....*....|....*....|....*
gi 499323051  150 SIAWAIASMYPERVRGLISLGAIHP 174
Cdd:pfam00561  81 LIALAYAAKYPDRVKALVLLGALDP 105
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
50-204 2.10e-18

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 82.36  E-value: 2.10e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  50 THDHVSVRGIRLhlaEAGSPTKPLVLLIHGAFGGWYDYREVIGPLADAGFHVAAIDLRGYGMSDKPPTGY-DLRHAAGEL 128
Cdd:COG2267   10 TRDGLRLRGRRW---RPAGSPRGTVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVdSFDDYVDDL 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499323051 129 SSVIAALGHDDAL---LVGSDTGASIAWAIASMYPERVRGLISLGAIHPLDMRRAIRRKPHLHVSDLSRLAPFRLPSFL 204
Cdd:COG2267   87 RAALDALRARPGLpvvLLGHSMGGLIALLYAARYPDRVAGLVLLAPAYRADPLLGPSARWLRALRLAEALARIDVPVLV 165
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
 43-166 5.75e-16

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 76.96  E-value: 5.75e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  43 IALDGPFTHDHVSVRGIRLHLAEAGSptKPLVLLIHGAFGGWYDYREVIGPLADAGfHVAAIDLRGYGMSDKPPTGYDLR 122
Cdd:PRK03592   1 FGVEPPGEMRRVEVLGSRMAYIETGE--GDPIVFLHGNPTSSYLWRNIIPHLAGLG-RCLAPDLIGMGASDKPDIDYTFA 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 499323051 123 HAAGELSSVIAALGHDDALLVGSDTGASIAWAIASMYPERVRGL 166
Cdd:PRK03592  78 DHARYLDAWFDALGLDDVVLVGHDWGSALGFDWAARHPDRVRGI 121
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
 46-167 1.46e-15

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 75.77  E-value: 1.46e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  46 DGPFTHDHVSVRG-----IRLHLAEAGSPTKPLVLLIHGAFGGWYDYREVIGPLADAGFHVAAIDLRGYGMSDKPPTGYD 120
Cdd:PRK00870  16 DYPFAPHYVDVDDgdggpLRMHYVDEGPADGPPVLLLHGEPSWSYLYRKMIPILAAAGHRVIAPDLIGFGRSDKPTRRED 95

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 499323051 121 ---LRHAAGeLSSVIAALGHDDALLVGSDTGASIAWAIASMYPERVRGLI 167
Cdd:PRK00870  96 ytyARHVEW-MRSWFEQLDLTDVTLVCQDWGGLIGLRLAAEHPDRFARLV 144
PLN03084 PLN03084
alpha/beta hydrolase fold protein; Provisional
 65-169 3.90e-12

alpha/beta hydrolase fold protein; Provisional


Pssm-ID: 178633  Cd Length: 383  Bit Score: 66.44  E-value: 3.90e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  65 EAGSPTKPLVLLIHGAFGGWYDYREVIGPLADaGFHVAAIDLRGYGMSDKPPTGYDLRHAAGE----LSSVIAALGHDDA 140
Cdd:PLN03084 121 ESGSNNNPPVLLIHGFPSQAYSYRKVLPVLSK-NYHAIAFDWLGFGFSDKPQPGYGFNYTLDEyvssLESLIDELKSDKV 199

                         90       100
                 ....*....|....*....|....*....
gi 499323051 141 LLVGSDTGASIAWAIASMYPERVRGLISL 169
Cdd:PLN03084 200 SLVVQGYFSPPVVKYASAHPDKIKKLILL 228
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
66-177 2.98e-11

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 62.34  E-value: 2.98e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  66 AGSPTKPLVLLIHGAFGG-WYDYREVIGPLADAGFHVAAIDLRGYGMSDKPPTGYDLRhaagELSSVIAAL-GHDDA--- 140
Cdd:COG1506   18 ADGKKYPVVVYVHGGPGSrDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDEVD----DVLAAIDYLaARPYVdpd 93

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 499323051 141 --LLVGSDTGASIAWAIASMYPERVRGLISLGAIHPLDM 177
Cdd:COG1506   94 riGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRS 132
PRK05855 PRK05855
SDR family oxidoreductase;
54-153 4.57e-11

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 63.46  E-value: 4.57e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  54 VSVRGIRLHLAEAGSPTKPLVLLIHgafgGWYD----YREVIGPLADAgFHVAAIDLRGYGMSDKPPT--GYDLRHAAGE 127
Cdd:PRK05855   8 VSSDGVRLAVYEWGDPDRPTVVLVH----GYPDnhevWDGVAPLLADR-FRVVAYDVRGAGRSSAPKRtaAYTLARLADD 82

                         90       100
                 ....*....|....*....|....*..
gi 499323051 128 LSSVIAALGHDDAL-LVGSDTGASIAW 153
Cdd:PRK05855  83 FAAVIDAVSPDRPVhLLAHDWGSIQGW 109
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 22-174 8.62e-10

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 59.19  E-value: 8.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  22 ATGAKRRLSSTIASIERSpgiialdGPfTHDHVSVRGIRLHLAEAGSPTKPLVLLIHGaFGGWYD-YREVIGPLAdAGFH 100
Cdd:PRK14875  90 IAPFARRFAPEGIDEEDA-------GP-APRKARIGGRTVRYLRLGEGDGTPVVLIHG-FGGDLNnWLFNHAALA-AGRP 159

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499323051 101 VAAIDLRGYGMSDKPPTGYDLRHAAGELSSVIAALGHDDALLVGSDTGASIAWAIASMYPERVRgliSLGAIHP 174
Cdd:PRK14875 160 VIALDLPGHGASSKAVGAGSLDELAAAVLAFLDALGIERAHLVGHSMGGAVALRLAARAPQRVA---SLTLIAP 230
PRK03204 PRK03204
haloalkane dehalogenase; Provisional
 55-167 3.12e-09

haloalkane dehalogenase; Provisional


Pssm-ID: 179554 [Multi-domain]  Cd Length: 286  Bit Score: 57.17  E-value: 3.12e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  55 SVRGiRLHLAEAGspTKPLVLLIHGAFGGWYDYREVIGPLADAgFHVAAIDLRGYGMSDKPPT-GYDLRHAAGELSSVIA 133
Cdd:PRK03204  21 SSRG-RIHYIDEG--TGPPILLCHGNPTWSFLYRDIIVALRDR-FRCVAPDYLGFGLSERPSGfGYQIDEHARVIGEFVD 96

                         90       100       110
                 ....*....|....*....|....*....|....
gi 499323051 134 ALGHDDALLVGSDTGASIAWAIASMYPERVRGLI 167
Cdd:PRK03204  97 HLGLDRYLSMGQDWGGPISMAVAVERADRVRGVV 130
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 50-168 1.41e-08

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 54.92  E-value: 1.41e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  50 THDHVSVRGIrLHLAEAGSPTKPLVLLIHGaFGGWYDYREVIGP-LADAGFHVAAIDLRGYGMSD-KP-----PTGYDLR 122
Cdd:COG1073   17 SRDGIKLAGD-LYLPAGASKKYPAVVVAHG-NGGVKEQRALYAQrLAELGFNVLAFDYRGYGESEgEPreegsPERRDAR 94

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 499323051 123 HAAGELSSViaaLGHDDALLV--GSDTGASIAWAIASMYPeRVRGLIS 168
Cdd:COG1073   95 AAVDYLRTL---PGVDPERIGllGISLGGGYALNAAATDP-RVKAVIL 138
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 74-209 1.49e-08

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 54.40  E-value: 1.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051   74 VLLIHGAfggWYDYREVIgPLADAGFHVAAIDLRGYGMSDKPPTGYDlrhAAGELSSVIAALG-HDDALLVGSDTGASIA 152
Cdd:pfam12697   1 VVLVHGA---GLSAAPLA-ALLAAGVAVLAPDLPGHGSSSPPPLDLA---DLADLAALLDELGaARPVVLVGHSLGGAVA 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 499323051  153 WAIASMYPerVRGLISLGAIHPLDMRRAiRRKPHLHVSDLSRLAPFRLPSFLHNLFH 209
Cdd:pfam12697  74 LAAAAAAL--VVGVLVAPLAAPPGLLAA-LLALLARLGAALAAPAWLAAESLARGFL 127
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 68-182 1.87e-08

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 54.14  E-value: 1.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051   68 SPTKPLVLLIHGaFG---GWYDyrEVIGPLADAGFHVAAIDLRGYGMSDkPPTGY--DLRHAAGELSSVIAAL----GHD 138
Cdd:pfam12146   1 GEPRAVVVLVHG-LGehsGRYA--HLADALAAQGFAVYAYDHRGHGRSD-GKRGHvpSFDDYVDDLDTFVDKIreehPGL 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 499323051  139 DALLVGSDTGASIAWAIASMYPERVRGLISLGA---IHPLDMRRAIR 182
Cdd:pfam12146  77 PLFLLGHSMGGLIAALYALRYPDKVDGLILSAPalkIKPYLAPPILK 123
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
50-186 5.89e-08

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 52.66  E-value: 5.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  50 THDHVSVRGirlHLAE-AGSPTKPLVLLIHGAFGGWYDYREVIGPLADAGFHVAAIDLRGYGMSDKPP-------TGYDL 121
Cdd:COG0412   10 TPDGVTLPG---YLARpAGGGPRPGVVVLHEIFGLNPHIRDVARRLAAAGYVVLAPDLYGRGGPGDDPdearalmGALDP 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499323051 122 RHAAGELSSVIAALGHDDAL------LVGSDTGASIAWAIASMYPeRVRGLISLGAIHPLDMRRAIRRKPH 186
Cdd:COG0412   87 ELLAADLRAALDWLKAQPEVdagrvgVVGFCFGGGLALLAAARGP-DLAAAVSFYGGLPADDLLDLAARIK 156
PLN02578 PLN02578
hydrolase
 57-171 1.17e-07

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 52.54  E-value: 1.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  57 RGIRLHLAE--AGSPtkplVLLIHGAFGGWYDYREVIGPLADAgFHVAAIDLRGYGMSDKPPTGYDLRHAAGELSSVIAA 134
Cdd:PLN02578  74 RGHKIHYVVqgEGLP----IVLIHGFGASAFHWRYNIPELAKK-YKVYALDLLGFGWSDKALIEYDAMVWRDQVADFVKE 148

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 499323051 135 LGHDDALLVGSDTGASIAWAIASMYPERVRGLISLGA 171
Cdd:PLN02578 149 VVKEPAVLVGNSLGGFTALSTAVGYPELVAGVALLNS 185
PLN02824 PLN02824
hydrolase, alpha/beta fold family protein
 57-187 1.30e-07

hydrolase, alpha/beta fold family protein


Pssm-ID: 178419 [Multi-domain]  Cd Length: 294  Bit Score: 52.05  E-value: 1.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  57 RGIRLHLAEAGsPTKPLVLLIHGaFGGWYD-YREVIGPLADAGfHVAAIDLRGYGMSDKP-----PTG--YDLRHAAGEL 128
Cdd:PLN02824  16 KGYNIRYQRAG-TSGPALVLVHG-FGGNADhWRKNTPVLAKSH-RVYAIDLLGYGYSDKPnprsaPPNsfYTFETWGEQL 92

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499323051 129 SSVIAALGHDDALLVGSDTGASIAWAIASMYPERVRGL----ISLGAIHpldmrraIRRKPHL 187
Cdd:PLN02824  93 NDFCSDVVGDPAFVICNSVGGVVGLQAAVDAPELVRGVmlinISLRGLH-------IKKQPWL 148
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 69-173 3.33e-07

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 47.90  E-value: 3.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  69 PTKPLVLLIHGAFGGWYDYREVIGPLADAGFHVAAIDLrgygmsdkPPTGYDLRHAAGELSSVIAAL----GHDDALLVG 144
Cdd:COG1075    3 ATRYPVVLVHGLGGSAASWAPLAPRLRAAGYPVYALNY--------PSTNGSIEDSAEQLAAFVDAVlaatGAEKVDLVG 74

                         90       100       110
                 ....*....|....*....|....*....|.
gi 499323051 145 SDTGASIA-WAIASM-YPERVRGLISLGAIH 173
Cdd:COG1075   75 HSMGGLVArYYLKRLgGAAKVARVVTLGTPH 105
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
70-179 3.96e-07

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 50.33  E-value: 3.96e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  70 TKPLVLLIHGAFGGWYDYREVIGPLADAGFHVAAIDLRGYGMSDKPPTGYDLRHAAGELSSVIAAL--GHDDALLVGSDT 147
Cdd:COG1647   14 GRKGVLLLHGFTGSPAEMRPLAEALAKAGYTVYAPRLPGHGTSPEDLLKTTWEDWLEDVEEAYEILkaGYDKVIVIGLSM 93

                         90       100       110
                 ....*....|....*....|....*....|..
gi 499323051 148 GASIAWAIASMYPErVRGLISLGAihPLDMRR 179
Cdd:COG1647   94 GGLLALLLAARYPD-VAGLVLLSP--ALKIDD 122
PRK10673 PRK10673
esterase;
59-179 1.23e-06

esterase;


Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 48.96  E-value: 1.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  59 IRLHLAEagSPTKPL-VLLIHGAFGGwYDYREVIGPLADAGFHVAAIDLRGYGMSDKPPTgYDLRHAAGELSSVIAALGH 137
Cdd:PRK10673   5 IRAQTAQ--NPHNNSpIVLVHGLFGS-LDNLGVLARDLVNDHDIIQVDMRNHGLSPRDPV-MNYPAMAQDLLDTLDALQI 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 499323051 138 DDALLVGSDTGASIAWAIASMYPERVRGLISLGaIHPLD--MRR 179
Cdd:PRK10673  81 EKATFIGHSMGGKAVMALTALAPDRIDKLVAID-IAPVDyhVRR 123
PLN02679 PLN02679
hydrolase, alpha/beta fold family protein
 68-169 2.83e-05

hydrolase, alpha/beta fold family protein


Pssm-ID: 178283 [Multi-domain]  Cd Length: 360  Bit Score: 45.22  E-value: 2.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  68 SPTKPLVLLIHGAFGGWYDYREVIGPLADAgFHVAAIDLRGYGMSDKPPT-GYDLRHAAGELSSVIAALGHDDALLVGSD 146
Cdd:PLN02679  85 TSSGPPVLLVHGFGASIPHWRRNIGVLAKN-YTVYAIDLLGFGASDKPPGfSYTMETWAELILDFLEEVVQKPTVLIGNS 163

                         90       100
                 ....*....|....*....|....*
gi 499323051 147 TGaSIAWAIASMYPER--VRGLISL 169
Cdd:PLN02679 164 VG-SLACVIAASESTRdlVRGLVLL 187
YpfH COG0400
Predicted esterase [General function prediction only];
67-190 3.71e-04

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 41.05  E-value: 3.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  67 GSPTKPLVLLIHGAFGGWYDYREVIGPLADAGFHVAAID---LRGYGM--------SDKPPTGYDLRHAAGELSSVIAAL 135
Cdd:COG0400    1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALPGAAVLAPRapvPEGPGGrawfdlsfLEGREDEEGLAAAAEALAAFIDEL 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499323051 136 ------GHDDALLVG-SDtGASIAWAIASMYPERVRGLISL-GAIHP---LDMRRAIRRKPHLHVS 190
Cdd:COG0400   81 earygiDPERIVLAGfSQ-GAAMALSLALRRPELLAGVVALsGYLPGeeaLPAPEAALAGTPVFLA 145
PRK08775 PRK08775
homoserine O-succinyltransferase;
53-173 6.83e-03

homoserine O-succinyltransferase;


Pssm-ID: 181553 [Multi-domain]  Cd Length: 343  Bit Score: 37.85  E-value: 6.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499323051  53 HVSVRGIRLHLAEAGSPTKPLVLLIHG--------------AFGGWYDYREVIGPLADAGFHVAAIDLRGY-GMSDKPPT 117
Cdd:PRK08775  40 HAGLEDLRLRYELIGPAGAPVVFVAGGisahrhvaatatfpEKGWWEGLVGSGRALDPARFRLLAFDFIGAdGSLDVPID 119

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 499323051 118 GYDlrhAAGELSSVIAALG-HDDALLVGSDTGASIAWAIASMYPERVRGLISLGAIH 173
Cdd:PRK08775 120 TAD---QADAIALLLDALGiARLHAFVGYSYGALVGLQFASRHPARVRTLVVVSGAH 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH