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Conserved domains on  [gi|499325016|ref|WP_011015508|]
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membrane protein insertase YidC [Corynebacterium glutamicum]

Protein Classification

membrane protein insertase YidC( domain architecture ID 11478361)

membrane protein insertase YidC functions as a membrane protein chaperone and as an independent insertase for membrane proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK00247 PRK00247
putative inner membrane protein translocase component YidC; Validated
 1-422 0e+00

putative inner membrane protein translocase component YidC; Validated


:

Pssm-ID: 178945 [Multi-domain]  Cd Length: 429  Bit Score: 735.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   1 MLDILIYPVSGVMKLWHLLLHNVAGLDDSLAWFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGKYD 80
Cdd:PRK00247   1 MLDIFIYPVSGVMKLWHLLLHNVLGLDDSLAWFASLFGLVITVRAIIAPFTWQQYKSGRTAAHIRPKRKALREEYKGKTD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  81 EASIRELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLGLYWALLRMARPEGGLENPVFQSIGFLTPEEVESFLAGRVSNV 160
Cdd:PRK00247  81 EASIRELQQKQKDLNKEYGYNPLAGCVPALIQIPVFLGLYQVLLRMARPEGGLENPVHQPIGFLTSEEVESFLQGRVFNV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 161 PLPAYVSMPTEQLKYLSTTQAEVLSFVLPLFITAAILTAINMAMSMYRSFQTNDYASGFSNGMLKFMIVMSILAPIFPLS 240
Cdd:PRK00247 161 PLPAYVSMPAEQLAYLGTTQATVLAFVLPLFIAAAVFTAINMAMSTYRSFQTNDHDSGFAVGMLKFLIVMAILAPIFPLS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 241 LGLTGPFPTAIALYWVSNNLWTLLQTIIMMVILERKYPLTDDFKVHHLEQRDIYRAKQKEKRIFLWTRRKNRALMILTPW 320
Cdd:PRK00247 241 LGLTGPFPTAIALYWVANNLWTLIQNIIMYLILERKYPLTDEFKEHHAEQRAQYREKQKEKKAFLWTLRRNRLRMIITPW 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 321 NASTLHATNVELTKTRTAEINEAKQARKEIANKRRETQREMNR-------AAMQRLKQRRAEVKAKKKGLIDASPNEDTP 393
Cdd:PRK00247 321 RAPELHAENAEIKKTRTAEKNEAKARKKEIAQKRRAAEREINRearqeraAAMARARARRAAVKAKKKGLIDASPNEDTP 400

                        410       420
                 ....*....|....*....|....*....
gi 499325016 394 SENEETKLSSPQVEPTTTAEPNREPSQED 422
Cdd:PRK00247 401 SENEESKGSPPQVEATTTAEPNREPSQED 429
 
Name Accession Description Interval E-value
PRK00247 PRK00247
putative inner membrane protein translocase component YidC; Validated
 1-422 0e+00

putative inner membrane protein translocase component YidC; Validated


Pssm-ID: 178945 [Multi-domain]  Cd Length: 429  Bit Score: 735.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   1 MLDILIYPVSGVMKLWHLLLHNVAGLDDSLAWFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGKYD 80
Cdd:PRK00247   1 MLDIFIYPVSGVMKLWHLLLHNVLGLDDSLAWFASLFGLVITVRAIIAPFTWQQYKSGRTAAHIRPKRKALREEYKGKTD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  81 EASIRELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLGLYWALLRMARPEGGLENPVFQSIGFLTPEEVESFLAGRVSNV 160
Cdd:PRK00247  81 EASIRELQQKQKDLNKEYGYNPLAGCVPALIQIPVFLGLYQVLLRMARPEGGLENPVHQPIGFLTSEEVESFLQGRVFNV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 161 PLPAYVSMPTEQLKYLSTTQAEVLSFVLPLFITAAILTAINMAMSMYRSFQTNDYASGFSNGMLKFMIVMSILAPIFPLS 240
Cdd:PRK00247 161 PLPAYVSMPAEQLAYLGTTQATVLAFVLPLFIAAAVFTAINMAMSTYRSFQTNDHDSGFAVGMLKFLIVMAILAPIFPLS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 241 LGLTGPFPTAIALYWVSNNLWTLLQTIIMMVILERKYPLTDDFKVHHLEQRDIYRAKQKEKRIFLWTRRKNRALMILTPW 320
Cdd:PRK00247 241 LGLTGPFPTAIALYWVANNLWTLIQNIIMYLILERKYPLTDEFKEHHAEQRAQYREKQKEKKAFLWTLRRNRLRMIITPW 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 321 NASTLHATNVELTKTRTAEINEAKQARKEIANKRRETQREMNR-------AAMQRLKQRRAEVKAKKKGLIDASPNEDTP 393
Cdd:PRK00247 321 RAPELHAENAEIKKTRTAEKNEAKARKKEIAQKRRAAEREINRearqeraAAMARARARRAAVKAKKKGLIDASPNEDTP 400

                        410       420
                 ....*....|....*....|....*....
gi 499325016 394 SENEETKLSSPQVEPTTTAEPNREPSQED 422
Cdd:PRK00247 401 SENEESKGSPPQVEATTTAEPNREPSQED 429
yidC_oxa1_cterm TIGR03592
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ...
 32-269 9.69e-38

membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274665 [Multi-domain]  Cd Length: 179  Bit Score: 134.92  E-value: 9.69e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   32 WFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGkydeaSIRELQKRQNDLNKEYGINPLAGCVPGLI 111
Cdd:TIGR03592   2 WGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKE-----DPQKLQQEMMKLYKEEGVNPLGGCLPLLI 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  112 QIPIVLGLYWALLRmarpegglenpvfqSIGFltpeEVESFLAGRVSNVPLPayvsmpteqlkylsttqaevlSFVLPLF 191
Cdd:TIGR03592  77 QMPIFIALYQVLLR--------------SIEL----RHAPFLWIIDLSSPDP---------------------YYILPIL 117

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499325016  192 ITAAILTAINMAMSMYRSFQTndyasgfsngmlkfMIVMSILAPIFPLSLGLTgpFPTAIALYWVSNNLWTLLQTIIM 269
Cdd:TIGR03592 118 MGVTMFLQQKLSPKGPPDPAQ--------------QKMMMYFMPLMFLFFFLS--FPAGLVLYWVVSNLFTIIQQLII 179
YidC COG0706
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
1-276 1.08e-34

Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440470 [Multi-domain]  Cd Length: 212  Bit Score: 127.93  E-value: 1.08e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   1 MLDILIYPVSGVMKLWHLLLHNvaglddslaWFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGkyd 80
Cdd:COG0706    5 WFGFIAKPLFWLLNFLHSLVGN---------WGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKD--- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  81 eaSIRELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLGLYWALLRMArpegGLENPVFQSIGFLTpeevesflagrvsnV 160
Cdd:COG0706   73 --DPQKLQQEMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSI----ELRHAPFLGIPDLS--------------A 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 161 PLPAYVSMPteqlkylsttqaevlsfvlplfITAAILTAINMAMSMyrsfqtndyaSGFSNGMLKFMIVMSilaPIFPLS 240
Cdd:COG0706  133 PDPYYIFLP----------------------ILMGVTMFLQQKLNP----------APAQDPQQKKMMYIM---PLMFLF 177

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 499325016 241 LGLTgpFPTAIALYWVSNNLWTLLQTIIMMVILERK 276
Cdd:COG0706  178 FFLS--FPAGLVLYWVVSNLLTIGQQLIINRRLDKK 211
60KD_IMP pfam02096
60Kd inner membrane protein;
32-270 4.50e-30

60Kd inner membrane protein;


Pssm-ID: 460443 [Multi-domain]  Cd Length: 187  Bit Score: 114.88  E-value: 4.50e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   32 WFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGKyDEAsireLQKRQNDLNKEYGINPLAGCVPGLI 111
Cdd:pfam02096   1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDD-RQK----LQQEMMKLYKKEGVNPLGGCLPMLI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  112 QIPIVLGLYWALLRMARPEGGlenpvfQSIGFLTPeevesflagrvsnvplpayvsmpteqlkyLSTTQAEVLSFVLPLF 191
Cdd:pfam02096  76 QMPIFIALYRVLRNSIELRHA------PFFLWIAD-----------------------------LSAPDPISILHYYILP 120

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499325016  192 ITAAILTAINMAMSMyrsfQTNDYASGFSNGMLKFMIVMSIlapIFPLSlgltgpFPTAIALYWVSNNLWTLLQTIIMM 270
Cdd:pfam02096 121 ILMGVTMFLQQKLTP----APQDQPPQMKMMMLYFMPLMFL---FFFLN------FPAGLVLYWVVSNLLSIGQQLIIN 186
5TM_YidC_Alb3 cd20070
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ...
 39-270 1.00e-26

Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410994 [Multi-domain]  Cd Length: 181  Bit Score: 105.54  E-value: 1.00e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  39 LVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGKydeasIRELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLG 118
Cdd:cd20070    7 LTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDD-----KQKLQQEMMKLYKEHGVNPLGGCLPLLIQMPIFIA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 119 LYWALLRMarpegglenPVFQSIGFLtpeevesflaGRVSNVPLPAYVsmpteqlkylsttqaevlsFVLPlfITAAILT 198
Cdd:cd20070   82 LYQVLRNS---------IELRGAPFL----------WWILDLSAPDPY-------------------YILP--ILMGVTM 121

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499325016 199 AINMAMSMyrsfQTNDYASGFSNGMLKFMIVMSIlapIFPLSlgltgpFPTAIALYWVSNNLWTLLQTIIMM 270
Cdd:cd20070  122 FLQQKLTP----TPTDDQAPQQKMMMYFMPVMFT---FIFLS------FPSGLVLYWLVSNLFSIIQQLIIN 180
 
Name Accession Description Interval E-value
PRK00247 PRK00247
putative inner membrane protein translocase component YidC; Validated
 1-422 0e+00

putative inner membrane protein translocase component YidC; Validated


Pssm-ID: 178945 [Multi-domain]  Cd Length: 429  Bit Score: 735.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   1 MLDILIYPVSGVMKLWHLLLHNVAGLDDSLAWFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGKYD 80
Cdd:PRK00247   1 MLDIFIYPVSGVMKLWHLLLHNVLGLDDSLAWFASLFGLVITVRAIIAPFTWQQYKSGRTAAHIRPKRKALREEYKGKTD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  81 EASIRELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLGLYWALLRMARPEGGLENPVFQSIGFLTPEEVESFLAGRVSNV 160
Cdd:PRK00247  81 EASIRELQQKQKDLNKEYGYNPLAGCVPALIQIPVFLGLYQVLLRMARPEGGLENPVHQPIGFLTSEEVESFLQGRVFNV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 161 PLPAYVSMPTEQLKYLSTTQAEVLSFVLPLFITAAILTAINMAMSMYRSFQTNDYASGFSNGMLKFMIVMSILAPIFPLS 240
Cdd:PRK00247 161 PLPAYVSMPAEQLAYLGTTQATVLAFVLPLFIAAAVFTAINMAMSTYRSFQTNDHDSGFAVGMLKFLIVMAILAPIFPLS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 241 LGLTGPFPTAIALYWVSNNLWTLLQTIIMMVILERKYPLTDDFKVHHLEQRDIYRAKQKEKRIFLWTRRKNRALMILTPW 320
Cdd:PRK00247 241 LGLTGPFPTAIALYWVANNLWTLIQNIIMYLILERKYPLTDEFKEHHAEQRAQYREKQKEKKAFLWTLRRNRLRMIITPW 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 321 NASTLHATNVELTKTRTAEINEAKQARKEIANKRRETQREMNR-------AAMQRLKQRRAEVKAKKKGLIDASPNEDTP 393
Cdd:PRK00247 321 RAPELHAENAEIKKTRTAEKNEAKARKKEIAQKRRAAEREINRearqeraAAMARARARRAAVKAKKKGLIDASPNEDTP 400

                        410       420
                 ....*....|....*....|....*....
gi 499325016 394 SENEETKLSSPQVEPTTTAEPNREPSQED 422
Cdd:PRK00247 401 SENEESKGSPPQVEATTTAEPNREPSQED 429
PRK03449 PRK03449
putative inner membrane protein translocase component YidC; Provisional
 1-275 3.24e-55

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 179580  Cd Length: 304  Bit Score: 184.88  E-value: 3.24e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   1 MLDILIYPVSGVMKLWHLLLHNVAGLDDSLAWFFSLFGLVITIRAII-APFTWQMyKSGRTAAHIRPHRAALREEYKGKY 79
Cdd:PRK03449   1 MLDFIYYPVSAILWFWHKLFSFVLGPDNGFAWALSVMFLVFTLRALLyKPFVRQI-RTTRKMQELQPQIKALQKKYGNDR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  80 DEASIrELQKRQndlnKEYGINPLAGCVPGLIQIPIVLGLYWALL---RMARPEGGLENPVFQSIG----FLTPEEVESF 152
Cdd:PRK03449  80 QKMAL-EMQKLQ----KEHGFNPILGCLPMLAQIPVFLGLFHVLRsfnRTGTGFGQLGMSVEENRNtpnyVFSAEDVQSF 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 153 LAGRVSNVPLPAYVSMPTEQLK-YLSTTQAEVLSFVLPLFITAAILTAINMAMSMYRsfQTNDYASGFSNGMLKFMIVMs 231
Cdd:PRK03449 155 LDARLFGAPLSAYITMPRSGLDaFVDFTRTNIILVGVPLMIIAGVATHFNSRASVAR--QSAEAAANPQTAMMNKLALW- 231

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 499325016 232 ilapIFPLSLGLTGPF-PTAIALYWVSNNLWTLLQTIIMMVILER 275
Cdd:PRK03449 232 ----VFPLGVLVGGPFlPLAILLYWVSNNIWTFGQQHYVFGKIDK 272
yidC_oxa1_cterm TIGR03592
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ...
 32-269 9.69e-38

membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274665 [Multi-domain]  Cd Length: 179  Bit Score: 134.92  E-value: 9.69e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   32 WFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGkydeaSIRELQKRQNDLNKEYGINPLAGCVPGLI 111
Cdd:TIGR03592   2 WGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKE-----DPQKLQQEMMKLYKEEGVNPLGGCLPLLI 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  112 QIPIVLGLYWALLRmarpegglenpvfqSIGFltpeEVESFLAGRVSNVPLPayvsmpteqlkylsttqaevlSFVLPLF 191
Cdd:TIGR03592  77 QMPIFIALYQVLLR--------------SIEL----RHAPFLWIIDLSSPDP---------------------YYILPIL 117

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499325016  192 ITAAILTAINMAMSMYRSFQTndyasgfsngmlkfMIVMSILAPIFPLSLGLTgpFPTAIALYWVSNNLWTLLQTIIM 269
Cdd:TIGR03592 118 MGVTMFLQQKLSPKGPPDPAQ--------------QKMMMYFMPLMFLFFFLS--FPAGLVLYWVVSNLFTIIQQLII 179
YidC COG0706
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
1-276 1.08e-34

Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440470 [Multi-domain]  Cd Length: 212  Bit Score: 127.93  E-value: 1.08e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   1 MLDILIYPVSGVMKLWHLLLHNvaglddslaWFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGkyd 80
Cdd:COG0706    5 WFGFIAKPLFWLLNFLHSLVGN---------WGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKD--- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  81 eaSIRELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLGLYWALLRMArpegGLENPVFQSIGFLTpeevesflagrvsnV 160
Cdd:COG0706   73 --DPQKLQQEMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSI----ELRHAPFLGIPDLS--------------A 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 161 PLPAYVSMPteqlkylsttqaevlsfvlplfITAAILTAINMAMSMyrsfqtndyaSGFSNGMLKFMIVMSilaPIFPLS 240
Cdd:COG0706  133 PDPYYIFLP----------------------ILMGVTMFLQQKLNP----------APAQDPQQKKMMYIM---PLMFLF 177

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 499325016 241 LGLTgpFPTAIALYWVSNNLWTLLQTIIMMVILERK 276
Cdd:COG0706  178 FFLS--FPAGLVLYWVVSNLLTIGQQLIINRRLDKK 211
60KD_IMP pfam02096
60Kd inner membrane protein;
32-270 4.50e-30

60Kd inner membrane protein;


Pssm-ID: 460443 [Multi-domain]  Cd Length: 187  Bit Score: 114.88  E-value: 4.50e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   32 WFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGKyDEAsireLQKRQNDLNKEYGINPLAGCVPGLI 111
Cdd:pfam02096   1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDD-RQK----LQQEMMKLYKKEGVNPLGGCLPMLI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  112 QIPIVLGLYWALLRMARPEGGlenpvfQSIGFLTPeevesflagrvsnvplpayvsmpteqlkyLSTTQAEVLSFVLPLF 191
Cdd:pfam02096  76 QMPIFIALYRVLRNSIELRHA------PFFLWIAD-----------------------------LSAPDPISILHYYILP 120

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499325016  192 ITAAILTAINMAMSMyrsfQTNDYASGFSNGMLKFMIVMSIlapIFPLSlgltgpFPTAIALYWVSNNLWTLLQTIIMM 270
Cdd:pfam02096 121 ILMGVTMFLQQKLTP----APQDQPPQMKMMMLYFMPLMFL---FFFLN------FPAGLVLYWVVSNLLSIGQQLIIN 186
5TM_YidC_Alb3 cd20070
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ...
 39-270 1.00e-26

Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410994 [Multi-domain]  Cd Length: 181  Bit Score: 105.54  E-value: 1.00e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  39 LVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGKydeasIRELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLG 118
Cdd:cd20070    7 LTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDD-----KQKLQQEMMKLYKEHGVNPLGGCLPLLIQMPIFIA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 119 LYWALLRMarpegglenPVFQSIGFLtpeevesflaGRVSNVPLPAYVsmpteqlkylsttqaevlsFVLPlfITAAILT 198
Cdd:cd20070   82 LYQVLRNS---------IELRGAPFL----------WWILDLSAPDPY-------------------YILP--ILMGVTM 121

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499325016 199 AINMAMSMyrsfQTNDYASGFSNGMLKFMIVMSIlapIFPLSlgltgpFPTAIALYWVSNNLWTLLQTIIMM 270
Cdd:cd20070  122 FLQQKLTP----TPTDDQAPQQKMMMYFMPVMFT---FIFLS------FPSGLVLYWLVSNLFSIIQQLIIN 180
PRK01315 PRK01315
putative inner membrane protein translocase component YidC; Provisional
 5-278 8.89e-26

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 234941  Cd Length: 329  Bit Score: 106.75  E-value: 8.89e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   5 LIYPVSGVMKLWHLLLHNVAGLDDSLAWFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGKYDEASi 84
Cdd:PRK01315  15 LYWVISGILVLFHTLLGFLFGPDSGLTWVLSIVGLVIVIRALLIPLFVKQIKSQRNMQEIQPKMKKIQEKYKGDRERMS- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  85 RELQKrqndLNKEYGINPLAGCVPGLIQIPIVLGLYwALLRMARPEGglenpvfQSIGFLTPEEVESFLAGRVSNVPLPA 164
Cdd:PRK01315  94 QEMMK----LYKETGTNPLSSCLPLLLQMPIFFALY-RVLDSAASRG-------DGIGPINPPLLESFRHAHIFGAPLAA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 165 YVSMPTEQlkYLSTTQaevlsfvlplfITAAILTAINMAMSMYRSFQ---TNDYASGFSNGMLKFMIVMSILAPIFPLSL 241
Cdd:PRK01315 162 TFLQALNA--GNTAVQ-----------VVAAVLIILMSASQFITQLQlmtKNMPPEAKTGPMAQQQKMLLYLFPLMFLVS 228

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 499325016 242 GLTgpFPTAIALYWVSNNLWTLLQTiiMMVIleRKYP 278
Cdd:PRK01315 229 GIA--FPVGVLFYWLTSNVWTMGQQ--FYVI--RNNP 259
5TM_Oxa1-like cd20069
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ...
 30-271 1.34e-20

Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410993 [Multi-domain]  Cd Length: 201  Bit Score: 89.12  E-value: 1.34e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  30 LAWFFSLFGLVITIRAIIAPFT-WQMYKSGRTAaHIRPHRAALREEYKGK---YDEASIRELQKRQNDLNKEYGINPLAG 105
Cdd:cd20069    2 LPWWATIAATTVALRLLLLPLViKSQRNAARMA-NLQPELQKLQEKLKEArasGDQLEAAEARKELKELMKKHNVNPLKS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 106 CVPGLIQIPIVLGLYWALLRMArpegGLENPVFQSIGF-----LTpeevesflagrvsnVPLPAYvsmpteqlkylsttq 180
Cdd:cd20069   81 LLLPLVQAPVFISFFFALRKMA----NLPVPSFKTGGLlwftdLT--------------VPDPYY--------------- 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 181 aevlsfVLPlfITAAILTAINMAMSMYRSFQtndyASGFSNGMLKFMIVMSILapIFPLSLGltgpFPTAIALYWVSNNL 260
Cdd:cd20069  128 ------ILP--ILTSLTFLATIELGAETGTS----GSPQSKTMKNVFRGLPVL--MIPFTAN----FPSAVFLYWITSNL 189

                        250
                 ....*....|.
gi 499325016 261 WTLLQTIIMMV 271
Cdd:cd20069  190 FSLAQNLLLRI 200
5TM_YidC_Oxa1_Alb3 cd19751
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ...
 34-271 2.61e-20

Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410992 [Multi-domain]  Cd Length: 189  Bit Score: 87.99  E-value: 2.61e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  34 FSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGK-YDEASIRELQKRQNDLNKEYGINPLAGCVPGLIQ 112
Cdd:cd19751    2 LSIIIVTILIRLALLPLTLKQQKSMRKMQVIRPEMEAIREKYKEKaSKDKVQQEMQKEMLGLYKKHGVNPMAGCLPLFIQ 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 113 IPIVLGLYWALLRMarpegglenPVFQSIGFLTPEEVESflagrvsnvPLPAYvsmpteqlkylsttqaevlsfVLPlfI 192
Cdd:cd19751   82 LPIFMAFYFAIMRT---------EEIRYHTFLWFFDLGQ---------PDYLY---------------------ILP--F 120

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499325016 193 TAAILTAINMAMSMYRSFQTNDYASgfsnGMLKFMIVMSILAPIFPLSlgltgpFPTAIALYWVSNNLWTLLQTIIMMV 271
Cdd:cd19751  121 VAGITTYFQFKMTMSHQQQMQMMQM----QMKVMLYVMPVMIIIAGLS------FPSALSLYWIISNLFMIIQTYFIVR 189
PRK01622 PRK01622
membrane protein insertase YidC;
3-275 1.21e-19

membrane protein insertase YidC;


Pssm-ID: 179310  Cd Length: 256  Bit Score: 87.88  E-value: 1.21e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   3 DILIYPVSGVMKLWHLLLHNVAGLddslawffSLFGLVITIRAIIAPFTWQMYKSGRTA----AHIRPHRAALREEYKGK 78
Cdd:PRK01622  39 HYFVYPFSFLIQFVAHHIGGSYGI--------AIIIVTLIIRSLMIPLAVSQYKSQRGMqekmAVMKPELDKIQAKLKVT 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  79 YDEASIRELQKRQNDLNKEYGINPLA-GCVPGLIQIPIVLGLYWALLRmarpegglenpvfqsigflTPE-EVESFLagr 156
Cdd:PRK01622 111 KDLEKQKEYQKEMMELYKSGNINPLAmGCLPLLIQMPILSAFYYAIRR-------------------TEEiASHSFL--- 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 157 vsnvplpayvsmpteqlkYLSTTQAEVLsfvlpLFITAAILTAINMAMSMyrSFQTNDYAsgfsngmLKFMIVMSILAPI 236
Cdd:PRK01622 169 ------------------WFNLGHADHI-----LPIIAGLTYFIQMKVSQ--SNGTSPEQ-------VQMLKIQGIMMPA 216

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 499325016 237 FPLSLGLTGpfPTAIALYWVSNNLWTLLQTIIMMVILER 275
Cdd:PRK01622 217 MILFMSFAA--PSALVLYWITGGLFLMGQTIVLRKVMER 253
PRK02944 PRK02944
YidC family membrane integrase SpoIIIJ;
5-266 5.50e-18

YidC family membrane integrase SpoIIIJ;


Pssm-ID: 179508  Cd Length: 255  Bit Score: 82.89  E-value: 5.50e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   5 LIYPVSGVMKLWHLLLHNVAGLddslawffSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGKyDEASI 84
Cdd:PRK02944  40 FVYPLSQLITYFANLFGSNYGL--------AIIVVTLLIRLLILPLMIKQTKSTKAMQALQPEMQKLKEKYSSK-DQATQ 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  85 RELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLGLYWALLRMarpegglenpvfQSIGfltpeeVESFLagrvsnvplpa 164
Cdd:PRK02944 111 QKLQQEMMQLFQKNGVNPLAGCLPIFIQMPILIAFYHAIMRT------------SEIS------KHSFL----------- 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 165 yvsmpteqlkYLSTTQAEVLsFVLPlfITAAILTAINMAMSMYRSFQTNDYasgfsngMLKFMIVMSILAPIFPLSlglt 244
Cdd:PRK02944 162 ----------WFDLGQADPY-YILP--IVAGITTFIQQKLMMAGTAGQNPQ-------MAMMLWLMPIMILIFAIN---- 217

                        250       260
                 ....*....|....*....|..
gi 499325016 245 gpFPTAIALYWVSNNLWTLLQT 266
Cdd:PRK02944 218 --FPAALSLYWVVGNIFMIAQT 237
PRK00145 PRK00145
putative inner membrane protein translocase component YidC; Provisional
 27-276 1.24e-17

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 234665 [Multi-domain]  Cd Length: 223  Bit Score: 81.33  E-value: 1.24e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  27 DDSLAWFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKGkydeaSIRELQKRQNDLNKEYGINPLAGC 106
Cdd:PRK00145  26 NPNFSYGIAIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKYKN-----DPQKLQQEMMKLYKEKGVNPLGGC 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 107 VPGLIQIPIVLGLYWALLRMARPEGglenpvfqsIGFLtpeevesflagrvsnvplpayvsmpteqlkYLSTTQAEVLSF 186
Cdd:PRK00145 101 LPLLIQWPILIALYYVFNNLTGING---------VSFL------------------------------WIKDLAKPDITW 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 187 VLPlfITAAILTAINMAMSMYRSFQTNDYASGFSNGMLKFMIVMSIlapifplslgltgPFPTAIALYWVSNNLWTLLQT 266
Cdd:PRK00145 142 ILP--ILSGATTYLSGYLMTKADSSQAGQMKTMNIGMSIFMGVMSW-------------KFKSALVLYWVIGNLIQIIQT 206

                        250
                 ....*....|
gi 499325016 267 IIMMVILERK 276
Cdd:PRK00145 207 YFIKKLELKK 216
PRK01318 PRK01318
membrane protein insertase; Provisional
 30-276 1.58e-15

membrane protein insertase; Provisional


Pssm-ID: 234942 [Multi-domain]  Cd Length: 521  Bit Score: 78.37  E-value: 1.58e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  30 LAWFFSLFG--------LVITIRAIIAPFTWQMYKSgrTAA--HIRPHRAALREEYKGkyDEasirelQKRQN---DLNK 96
Cdd:PRK01318 313 LDFLHSFVGnwgwaiilLTIIVKLLLFPLTYKSYVS--MAKmkVLQPKMQELKEKYKD--DP------QKMQQemmELYK 382

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  97 EYGINPLAGCVPGLIQIPIVLGLYWALlrmarpegglenpvfqsigfltPEEVEsflagrvsnvplpayvsmpteqLKyl 176
Cdd:PRK01318 383 KEKVNPLGGCLPILIQIPIFFALYKVL----------------------LVSIE----------------------LR-- 416

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 177 sttQAevlSFVL---------PLFITAAILTAINMAMSMYRSFQTNDYASGFSN-GMLKFM-IVMSIlapIFplslgltG 245
Cdd:PRK01318 417 ---HA---PFIGwihdlsapdPYFILHIGLLPILMGITMFLQQKLNPTPTDPMQaKIMKFMpLIFTF---FF-------L 480

                        250       260       270
                 ....*....|....*....|....*....|.
gi 499325016 246 PFPTAIALYWVSNNLWTLLQTIIMMVILERK 276
Cdd:PRK01318 481 SFPAGLVLYWIVNNLLTIIQQYLINRRLEKK 511
PRK02201 PRK02201
putative inner membrane protein translocase component YidC; Provisional
 4-301 1.27e-09

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 235012  Cd Length: 357  Bit Score: 59.26  E-value: 1.27e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016   4 ILIYPVSGVMKlwHLLLHNVAGLDDSLAWFFSLFGLVITIRAIIAPFTWQMYKSGRTAAHIRPHRAALREEYKG-KYDEA 82
Cdd:PRK02201 107 LFVYPIAQIIL--SIMASQSLSELYGWSTILAIIVVVLIIRLISFLITFKSTFNQEKQEELQGKKAKIDAKYKDyKKDKQ 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  83 SIRELQKRQNDLNKEYGINPLAGCVPGLIQIPIVLGLyWALLRMARPeggLENPVFQSIGFltpeevesflagrvSNVPl 162
Cdd:PRK02201 185 MKQRKQQEIQELYKKHNISPFSPFVQMFVTLPIFIAV-YRVVQSLPS---IKVTTWLGIDL--------------SATS- 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 163 paYVSMPTEQLKYLSttqaeVLSFVLPLFITAAILTAInMAMSMYRSFQTNDYASGFSNGMLKFMIVMSILAPIFPLSlg 242
Cdd:PRK02201 246 --WQEIFAGNWIYLP-----ILIIVVPVQALSQLLPQI-LNKKKNKERTLNVKEKEALKKQNKTQNIISIVFIFFGVI-- 315

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 499325016 243 ltgpFPTAIALYWVSNNLWTLLQTIImmvilerkypltddfkVHHLEQRDIYRAKQKEK 301
Cdd:PRK02201 316 ----FAAGVQIYWIIGGIWTILQTLG----------------IHYFKKRKFYKQKYEPK 354
PRK01001 PRK01001
putative inner membrane protein translocase component YidC; Provisional
 12-120 7.15e-06

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 234887 [Multi-domain]  Cd Length: 795  Bit Score: 48.26  E-value: 7.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  12 VMKLWHLLlhnvaglddSLAWFFSLFGLVITIRAIIAPF-TWQMyKSGRTAAHIRPHRAALREEYKgkydeasiRELQKR 90
Cdd:PRK01001 565 IMKFFKFL---------TGSWGISIILLTVFLKLLLYPLnAWSI-RSMRRMQKLSPYIQEIQQKYK--------KEPKRA 626

                         90       100       110
                 ....*....|....*....|....*....|...
gi 499325016  91 QND---LNKEYGINPLAGCVPGLIQIPIVLGLY 120
Cdd:PRK01001 627 QMEimaLYKTNKVNPITGCLPLLIQLPFLIAMF 659
PRK02463 PRK02463
OxaA-like protein precursor; Provisional
 15-276 2.67e-05

OxaA-like protein precursor; Provisional


Pssm-ID: 235040  Cd Length: 307  Bit Score: 45.88  E-value: 2.67e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  15 LWHLLLHNVAGLDDSLAWFFSL-FGLVITI-----RAIIAPF----TWQM-YKSGRTA--AHI-RPHRAALREEYKGKYD 80
Cdd:PRK02463  37 IWNFLGAPMSYFIDYFANNLGLgFGLAIIIvtiivRLIILPLglyqSWKAtYQSEKMAylKPVfEPINERLKNATTQEEK 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016  81 EASIRELQKRQndlnKEYGINPLA--GCVPGLIQIPIVLGLYWAllrmARPEGGLENPVFQSIGFLTPEevesflagrvs 158
Cdd:PRK02463 117 MAAQTELMAAQ----RENGISMLGgiGCLPLLIQMPFFSALYFA----AQYTKGVSTSTFLGIDLGSPS----------- 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499325016 159 nvplpayvsmpteqlkylsttqaevlsfvLPLFITAAILTAINMAMSMYrsfqtnDYASGFSNGMLKFMIVMSILAPIFP 238
Cdd:PRK02463 178 -----------------------------LVLTAIIGVLYFFQSWLSMM------GVPEEQREQMKAMMYMMPIMMVVFS 222

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 499325016 239 LSLgltgpfPTAIALYWVSNNLWTLLQTIIMMVILERK 276
Cdd:PRK02463 223 FSS------PAGVGLYWLVGGFFSIIQQLITTYILKPR 254
PRK02654 PRK02654
putative inner membrane protein translocase component YidC; Provisional
 73-125 3.67e-05

putative inner membrane protein translocase component YidC; Provisional


Pssm-ID: 235058  Cd Length: 375  Bit Score: 45.74  E-value: 3.67e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 499325016  73 EEYKGKY-DEASirELQKRQNDLNKEYGiNPLAGCVPGLIQIPIVLGLYwALLR 125
Cdd:PRK02654  68 AEIQERYkNDPQ--KQQEEMGKLMKEFG-NPLAGCLPLLVQMPILFALF-ATLR 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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