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Conserved domains on  [gi|499391505|ref|WP_011078972|]
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MULTISPECIES: Sec-independent protein translocase subunit TatA [Vibrio]

Protein Classification

Sec-independent protein translocase subunit TatA( domain architecture ID 10012220)

Sec-independent protein translocase subunit TatA may form the protein-conducting channel of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
tatA PRK04598
twin-arginine translocase subunit TatA;
1-78 1.69e-41

twin-arginine translocase subunit TatA;


:

Pssm-ID: 179867  Cd Length: 81  Bit Score: 129.98  E-value: 1.69e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEE---SEKKDADFEPKSLEQQSKQAATESKKDKEQ 77
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEEsakANKKDADFEPKNLEQAKTEAAAEKKKDKEQ 80


                .
gi 499391505 78 A 78
Cdd:PRK04598 81 A 81
 
Name Accession Description Interval E-value
tatA PRK04598
twin-arginine translocase subunit TatA;
1-78 1.69e-41

twin-arginine translocase subunit TatA;


Pssm-ID: 179867  Cd Length: 81  Bit Score: 129.98  E-value: 1.69e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEE---SEKKDADFEPKSLEQQSKQAATESKKDKEQ 77
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEEsakANKKDADFEPKNLEQAKTEAAAEKKKDKEQ 80


                .
gi 499391505 78 A 78
Cdd:PRK04598 81 A 81
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-75 2.09e-17

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 68.81  E-value: 2.09e-17
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKDadfEPKSLEQQSKQAATESKKDK 75
Cdd:COG1826   1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDE---ELKEEELRKSEKEAEELKKA 72
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 3-49 1.28e-16

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 66.09  E-value: 1.28e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 499391505   3 GISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESE 49
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEEDE 47
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-52 1.27e-09

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 48.46  E-value: 1.27e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 499391505   4 ISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKD 52
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEK 49
 
Name Accession Description Interval E-value
tatA PRK04598
twin-arginine translocase subunit TatA;
1-78 1.69e-41

twin-arginine translocase subunit TatA;


Pssm-ID: 179867  Cd Length: 81  Bit Score: 129.98  E-value: 1.69e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEE---SEKKDADFEPKSLEQQSKQAATESKKDKEQ 77
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEEsakANKKDADFEPKNLEQAKTEAAAEKKKDKEQ 80


                .
gi 499391505 78 A 78
Cdd:PRK04598 81 A 81
tatA PRK02958
Sec-independent protein translocase subunit TatA;
1-50 5.06e-24

Sec-independent protein translocase subunit TatA;


Pssm-ID: 235091  Cd Length: 73  Bit Score: 85.79  E-value: 5.06e-24
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEK 50
Cdd:PRK02958  1 MGSFSIWHWLIVLVIVVLVFGTKKLRNIGSDLGGAVKGFKDGMKEGETPQ 50
tatA PRK01833
Sec-independent protein translocase subunit TatA;
1-78 6.33e-24

Sec-independent protein translocase subunit TatA;


Pssm-ID: 167284  Cd Length: 74  Bit Score: 85.32  E-value: 6.33e-24
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESekKDADFepKSLEQQSKQAATESKKDKEQA 78
Cdd:PRK01833  1 MGGISIWQLLIIVAIIVLLFGTKKLRTLGTDLGESVKGFKKAMADDKP--KDAEF--EKVEAKEAASTEQKAKEKEQA 74
tatA PRK03554
Sec-independent protein translocase subunit TatA;
1-74 3.99e-22

Sec-independent protein translocase subunit TatA;


Pssm-ID: 179592  Cd Length: 89  Bit Score: 81.26  E-value: 3.99e-22
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEK----KDADFEPKSL-EQQSKQAATESKKD 74
Cdd:PRK03554  1 MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQdktsQDADFTAKTIaDKQADTNQEQAKTE 79
tatE PRK03625
twin-arginine translocase subunit TatE;
1-56 2.41e-19

twin-arginine translocase subunit TatE;


Pssm-ID: 179612  Cd Length: 67  Bit Score: 73.65  E-value: 2.41e-19
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEE-SEKKDADFE 56
Cdd:PRK03625  1 MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMNDDDaAAKKGADVD 57
tatE PRK01614
Sec-independent protein translocase subunit TatA;
1-76 2.23e-18

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234965  Cd Length: 85  Bit Score: 71.85  E-value: 2.23e-18
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKDADFEPKSLEQQSKQAATESKKDKE 76
Cdd:PRK01614  1 MEGLSITKLLVVGILIVLLFGTSKLRTLGADLGAALKGFKKAMRNDDEVSTSVLGETKMSAETKTVAETKAASDSQ 76
tatA PRK00442
twin-arginine translocase TatA/TatE family subunit;
3-70 1.72e-17

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234764  Cd Length: 92  Bit Score: 69.52  E-value: 1.72e-17
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499391505  3 GISIWQ-LLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKDADFEPKSLEQQSKQAATE 70
Cdd:PRK00442  2 GIFDWKhWIVILVVVVLVFGTKKLKNLGSDVGESIKGFRKAMNEDEKEDKPAEQPAPPAQPVPPVQNTA 70
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-75 2.09e-17

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 68.81  E-value: 2.09e-17
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKDadfEPKSLEQQSKQAATESKKDK 75
Cdd:COG1826   1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDE---ELKEEELRKSEKEAEELKKA 72
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 3-49 1.28e-16

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 66.09  E-value: 1.28e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 499391505   3 GISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESE 49
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEEDE 47
tatA PRK00720
twin-arginine translocase TatA/TatE family subunit;
1-74 3.91e-14

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234822  Cd Length: 78  Bit Score: 60.83  E-value: 3.91e-14
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKDADFEPKSLEQQSKQAATESKKD 74
Cdd:PRK00720  1 MGSFSIWHWLIVLAVVLLLFGRGKISELMGDVAKGIKSFKKGMADDDAPPAEPPEPVRTIDHKADEPVAPVKKD 74
tatA PRK04561
twin arginine translocase protein A; Provisional
 1-75 5.43e-13

twin arginine translocase protein A; Provisional


Pssm-ID: 179864  Cd Length: 75  Bit Score: 58.00  E-value: 5.43e-13
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKDADFEPKSLEqQSKQAATESKKDK 75
Cdd:PRK04561  1 MGSFSIWHWLVVLVIVLLVFGTKRLTSGAKDLGSAVKEFKKGMHDDDKPAGQLGDDSRSAE-QAREAQAERDRDA 74
tatA PRK14857
TatA/E family twin arginine-targeting protein translocase;
3-77 2.58e-11

TatA/E family twin arginine-targeting protein translocase;


Pssm-ID: 184859  Cd Length: 90  Bit Score: 53.96  E-value: 2.58e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499391505  3 GISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESE-KKDADFE------PKSLEQQSKQAATESKKDK 75
Cdd:PRK14857  5 GIGLPEMAVILVIALLVFGPKKLPEIGRSLGKTLKGFQEASKEFENEiKREMAEPeqevkaPAELESNQTNEANQEQVDA 84


                ..
gi 499391505 76 EQ 77
Cdd:PRK14857 85 EN 86
tatA PRK00575
Sec-independent protein translocase subunit TatA;
1-54 4.64e-10

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234797 [Multi-domain]  Cd Length: 92  Bit Score: 50.89  E-value: 4.64e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKDAD 54
Cdd:PRK00575  1 MGSLSPWHWAILAVVVILLFGAKKLPDAARSLGKSLRIFKSEVKEMQSDNKAEA 54
tatA PRK14860
twin arginine translocase protein A; Provisional
 1-54 6.97e-10

twin arginine translocase protein A; Provisional


Pssm-ID: 184862  Cd Length: 64  Bit Score: 49.73  E-value: 6.97e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKDAD 54
Cdd:PRK14860  1 MFGFGMPELIVILVIALVVFGPAKLPQLGQALGGAIRNFKKASNEEDVVTINNE 54
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-52 1.27e-09

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 48.46  E-value: 1.27e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 499391505   4 ISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKD 52
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEK 49
tatA PRK14859
twin arginine translocase protein A; Provisional
 1-60 1.75e-09

twin arginine translocase protein A; Provisional


Pssm-ID: 184861  Cd Length: 63  Bit Score: 48.57  E-value: 1.75e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEES---EKKDADFEPKSL 60
Cdd:PRK14859  1 MFGIGMPELIVILVIVLIVFGAGKLPEIGGGLGKSIKNFKKATSEKEEieiKPTKKEDKKKKK 63
tatA PRK01470
twin arginine translocase protein A; Provisional
 3-52 7.41e-08

twin arginine translocase protein A; Provisional


Pssm-ID: 179298  Cd Length: 51  Bit Score: 44.08  E-value: 7.41e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 499391505  3 GISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKD 52
Cdd:PRK01470  2 GMSFSHLLIVLLIIFVLFGAGKLPQVMSDLAKGLKAFKDGMKDDGSDNDK 51
tatA PRK14861
twin arginine translocase protein A; Provisional
 1-58 1.35e-06

twin arginine translocase protein A; Provisional


Pssm-ID: 237837  Cd Length: 61  Bit Score: 41.11  E-value: 1.35e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 499391505  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKAMNEEESEKKDADFEPK 58
Cdd:PRK14861  2 FSNIGFPGLILILVVALIIFGPKKLPELGKALGKTLREFKKATKELTDDDFQEKKKKE 59
tatA PRK14858
twin arginine translocase protein A; Provisional
 1-78 3.15e-06

twin arginine translocase protein A; Provisional


Pssm-ID: 184860  Cd Length: 108  Bit Score: 41.39  E-value: 3.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499391505   1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKKA-------MNEEESEKKDADFEPKSLEQQSKQAATESKK 73
Cdd:PRK14858   1 MFGIGMPELIVILVIALIVIGPQKLPDLARSLGRGLAEFKKAtddfkqsMQEESRTAEEKEKAEKLAETKKEAEAPEAKA 80


                 ....*
gi 499391505  74 DKEQA 78
Cdd:PRK14858  81 EEDQA 85
tatA PRK00191
twin arginine translocase protein A; Provisional
 7-66 1.26e-05

twin arginine translocase protein A; Provisional


Pssm-ID: 234683 [Multi-domain]  Cd Length: 84  Bit Score: 39.17  E-value: 1.26e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 499391505  7 WQLLIIAVIVVLLFGTKKLRGIGSDLGGAIKGFKkamnEEESEKKDADFEPKSLEQQSKQ 66
Cdd:PRK00191  6 WEIGIIVLLIIVLFGAKKLPDAARSIGRSMRIFK----SEVKEMSKDDQTPEQQQQQPQQ 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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