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Conserved domains on  [gi|499449142|ref|WP_011136606|]
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GFA family protein [Chromobacterium violaceum]

Protein Classification

GFA family protein( domain architecture ID 10007990)

GFA family protein similar to bacterial glutathione-dependent formaldehyde-activating enzyme, which catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione, and to eukaryotic centromere protein V, which plays a role in the distribution of pericentromeric heterochromatin in interphase nuclei

CATH:  2.170.150.70
Gene Ontology:  GO:0016846|GO:0046872

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3791 COG3791
Uncharacterized conserved protein [Function unknown];
1-105 1.65e-15

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443005  Cd Length: 132  Bit Score: 68.12  E-value: 1.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499449142   1 MYILGACHCGNISFELDWpddDAIPARRCGCGFCRKHGGVWTAS----PGGRLAVTlRDRRRVSHYRFgTGTADFHICSD 76
Cdd:COG3791    2 MTLTGSCLCGAVRFEVDG---PPLRVGACHCSICRKATGSAFAAvalvPADAFRLT-SGEDALTTYRS-SATAERHFCPT 76

                         90       100
                 ....*....|....*....|....*....
gi 499449142  77 CGVAPLVTSEIGGRLHAvVSVNAFETPDL 105
Cdd:COG3791   77 CGSPLFYRRRGGPGLVA-VNAGLLDDPDG 104
 
Name Accession Description Interval E-value
COG3791 COG3791
Uncharacterized conserved protein [Function unknown];
1-105 1.65e-15

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443005  Cd Length: 132  Bit Score: 68.12  E-value: 1.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499449142   1 MYILGACHCGNISFELDWpddDAIPARRCGCGFCRKHGGVWTAS----PGGRLAVTlRDRRRVSHYRFgTGTADFHICSD 76
Cdd:COG3791    2 MTLTGSCLCGAVRFEVDG---PPLRVGACHCSICRKATGSAFAAvalvPADAFRLT-SGEDALTTYRS-SATAERHFCPT 76

                         90       100
                 ....*....|....*....|....*....
gi 499449142  77 CGVAPLVTSEIGGRLHAvVSVNAFETPDL 105
Cdd:COG3791   77 CGSPLFYRRRGGPGLVA-VNAGLLDDPDG 104
 
Name Accession Description Interval E-value
COG3791 COG3791
Uncharacterized conserved protein [Function unknown];
1-105 1.65e-15

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443005  Cd Length: 132  Bit Score: 68.12  E-value: 1.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499449142   1 MYILGACHCGNISFELDWpddDAIPARRCGCGFCRKHGGVWTAS----PGGRLAVTlRDRRRVSHYRFgTGTADFHICSD 76
Cdd:COG3791    2 MTLTGSCLCGAVRFEVDG---PPLRVGACHCSICRKATGSAFAAvalvPADAFRLT-SGEDALTTYRS-SATAERHFCPT 76

                         90       100
                 ....*....|....*....|....*....
gi 499449142  77 CGVAPLVTSEIGGRLHAvVSVNAFETPDL 105
Cdd:COG3791   77 CGSPLFYRRRGGPGLVA-VNAGLLDDPDG 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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