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Conserved domains on  [gi|499491112|ref|WP_011177752|]
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SMC-Scp complex subunit ScpB [Picrophilus oshimae]

Protein Classification

SMC-Scp complex subunit ScpB( domain architecture ID 10513533)

SMC-Scp complex subunit ScpB participates in chromosomal partition during cell division and is a component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer

CATH:  1.10.10.10
Gene Ontology:  GO:0051304|GO:0006260|GO:0051301
PubMed:  23541893
SCOP:  4000257

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_ScpB pfam04079
Segregation and condensation complex subunit ScpB; This is a family of prokaryotic proteins ...
 6-150 5.23e-33

Segregation and condensation complex subunit ScpB; This is a family of prokaryotic proteins that form one of the subunits, ScpB, of the segregation and condensation complex, condensin, that plays a key role in the maintenance of the chromosome. In prokaryotes the complex consists of three proteins, SMC, ScpA (kleisin) and ScpB. ScpB dimerizes and binds to ScpA. As originally predicted, ScpB is structurally a winged-helix at both its N- and C-terminal halves. IN Bacillus subtilis,one Smc dimer is bridged by a single ScpAB to generate asymmetric tripartite rings analogous to eukaryotic SMC complex ring-shaped assemblies.


:

Pssm-ID: 427697  Cd Length: 159  Bit Score: 114.18  E-value: 5.23e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499491112    6 RKVEAILYSCEEPLKVSDIADYLKvSNDDVIRAMKLIARSYNEINSTLEIKKIGNKYKIQLSNDFNDVVYPFVKK----D 81
Cdd:pfam04079   1 AIIEALLFVAGEPLSLEELAKILG-SKEEVREALDELKEEYEDRDRGLELVEVAGGYRLQTKPEYAEVVKRLVKEgkptR 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499491112   82 LDKRDIAMLSYIYGKPGVIAGELRENFGYNFMESVKKLKAEKLITSHKYRNT----FKYHVTKNFYVRFNVKD 150
Cdd:pfam04079  80 LSQAALETLAIIAYRQPITRAEIEEIRGVNSDGVVRTLLERGLIEEVGRKETpgrpILYGTTEKFLDYFGLKS 152
 
Name Accession Description Interval E-value
SMC_ScpB pfam04079
Segregation and condensation complex subunit ScpB; This is a family of prokaryotic proteins ...
 6-150 5.23e-33

Segregation and condensation complex subunit ScpB; This is a family of prokaryotic proteins that form one of the subunits, ScpB, of the segregation and condensation complex, condensin, that plays a key role in the maintenance of the chromosome. In prokaryotes the complex consists of three proteins, SMC, ScpA (kleisin) and ScpB. ScpB dimerizes and binds to ScpA. As originally predicted, ScpB is structurally a winged-helix at both its N- and C-terminal halves. IN Bacillus subtilis,one Smc dimer is bridged by a single ScpAB to generate asymmetric tripartite rings analogous to eukaryotic SMC complex ring-shaped assemblies.


Pssm-ID: 427697  Cd Length: 159  Bit Score: 114.18  E-value: 5.23e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499491112    6 RKVEAILYSCEEPLKVSDIADYLKvSNDDVIRAMKLIARSYNEINSTLEIKKIGNKYKIQLSNDFNDVVYPFVKK----D 81
Cdd:pfam04079   1 AIIEALLFVAGEPLSLEELAKILG-SKEEVREALDELKEEYEDRDRGLELVEVAGGYRLQTKPEYAEVVKRLVKEgkptR 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499491112   82 LDKRDIAMLSYIYGKPGVIAGELRENFGYNFMESVKKLKAEKLITSHKYRNT----FKYHVTKNFYVRFNVKD 150
Cdd:pfam04079  80 LSQAALETLAIIAYRQPITRAEIEEIRGVNSDGVVRTLLERGLIEEVGRKETpgrpILYGTTEKFLDYFGLKS 152
ScpB COG1386
Chromosome segregation and condensation protein ScpB [Transcription];
1-150 6.93e-25

Chromosome segregation and condensation protein ScpB [Transcription];


Pssm-ID: 440996  Cd Length: 181  Bit Score: 94.08  E-value: 6.93e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499491112   1 MDDLSRKVEAILYSCEEPLKVSDIADYLKVSNDDVIRAMKLIARSYNEINSTLEIKKIGNKYKIQLSNDFNDVVYPFVK- 79
Cdd:COG1386    3 RAELKAIIEALLFAAGEPLSLEELAELLGLDEEEVEEALEELAAEYASRGRGIELVEVAGGYRLQTRPEYAPYVRRLLKe 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499491112  80 ---KDLDKRDIAMLSYIYGKPGVIAGELRENFGYNFMESVKKLKAEKLITSHKYRNT----FKYHVTKNFYVRFNVKD 150
Cdd:COG1386   83 ekpKRLSRAALETLAIIAYRQPVTRAEIEEIRGVNVSGVIRTLLERGLIREVGRKEVpgrpILYGTTEKFLDYFGLKS 160
scpB PRK00135
segregation and condensation protein B; Reviewed
 8-80 5.83e-05

segregation and condensation protein B; Reviewed


Pssm-ID: 234657  Cd Length: 188  Bit Score: 41.03  E-value: 5.83e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499491112   8 VEAILY-SCEEPLKVSDIADYLKVSNDDVIRAMKLIARSYNEINSTLEIKKIGNKYKIQLSNDFNDVVYPFVKK 80
Cdd:PRK00135   9 IEALLFvSGEEGLSLEQLAEILELEPTEVQQLLEELQEKYEGDDRGLKLIEFNDVYKLVTKEENADYLQKLVKT 82
 
Name Accession Description Interval E-value
SMC_ScpB pfam04079
Segregation and condensation complex subunit ScpB; This is a family of prokaryotic proteins ...
 6-150 5.23e-33

Segregation and condensation complex subunit ScpB; This is a family of prokaryotic proteins that form one of the subunits, ScpB, of the segregation and condensation complex, condensin, that plays a key role in the maintenance of the chromosome. In prokaryotes the complex consists of three proteins, SMC, ScpA (kleisin) and ScpB. ScpB dimerizes and binds to ScpA. As originally predicted, ScpB is structurally a winged-helix at both its N- and C-terminal halves. IN Bacillus subtilis,one Smc dimer is bridged by a single ScpAB to generate asymmetric tripartite rings analogous to eukaryotic SMC complex ring-shaped assemblies.


Pssm-ID: 427697  Cd Length: 159  Bit Score: 114.18  E-value: 5.23e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499491112    6 RKVEAILYSCEEPLKVSDIADYLKvSNDDVIRAMKLIARSYNEINSTLEIKKIGNKYKIQLSNDFNDVVYPFVKK----D 81
Cdd:pfam04079   1 AIIEALLFVAGEPLSLEELAKILG-SKEEVREALDELKEEYEDRDRGLELVEVAGGYRLQTKPEYAEVVKRLVKEgkptR 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499491112   82 LDKRDIAMLSYIYGKPGVIAGELRENFGYNFMESVKKLKAEKLITSHKYRNT----FKYHVTKNFYVRFNVKD 150
Cdd:pfam04079  80 LSQAALETLAIIAYRQPITRAEIEEIRGVNSDGVVRTLLERGLIEEVGRKETpgrpILYGTTEKFLDYFGLKS 152
ScpB COG1386
Chromosome segregation and condensation protein ScpB [Transcription];
1-150 6.93e-25

Chromosome segregation and condensation protein ScpB [Transcription];


Pssm-ID: 440996  Cd Length: 181  Bit Score: 94.08  E-value: 6.93e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499491112   1 MDDLSRKVEAILYSCEEPLKVSDIADYLKVSNDDVIRAMKLIARSYNEINSTLEIKKIGNKYKIQLSNDFNDVVYPFVK- 79
Cdd:COG1386    3 RAELKAIIEALLFAAGEPLSLEELAELLGLDEEEVEEALEELAAEYASRGRGIELVEVAGGYRLQTRPEYAPYVRRLLKe 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499491112  80 ---KDLDKRDIAMLSYIYGKPGVIAGELRENFGYNFMESVKKLKAEKLITSHKYRNT----FKYHVTKNFYVRFNVKD 150
Cdd:COG1386   83 ekpKRLSRAALETLAIIAYRQPVTRAEIEEIRGVNVSGVIRTLLERGLIREVGRKEVpgrpILYGTTEKFLDYFGLKS 160
scpB PRK00135
segregation and condensation protein B; Reviewed
 8-80 5.83e-05

segregation and condensation protein B; Reviewed


Pssm-ID: 234657  Cd Length: 188  Bit Score: 41.03  E-value: 5.83e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499491112   8 VEAILY-SCEEPLKVSDIADYLKVSNDDVIRAMKLIARSYNEINSTLEIKKIGNKYKIQLSNDFNDVVYPFVKK 80
Cdd:PRK00135   9 IEALLFvSGEEGLSLEQLAEILELEPTEVQQLLEELQEKYEGDDRGLKLIEFNDVYKLVTKEENADYLQKLVKT 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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