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Conserved domains on  [gi|499591371|ref|WP_011272124|]
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YfcC family protein [Haemophilus influenzae]

Protein Classification

YfcC family protein( domain architecture ID 10787488)

YfcC family protein similar to Escherichia coli YfcC, which upregulates the expression of aceA and aceB, the key genes in glyoxylate shunt

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YfcC COG1288
Predicted membrane transporter YfcC, affects glyoxylate shunt [General function prediction ...
4-507 0e+00

Predicted membrane transporter YfcC, affects glyoxylate shunt [General function prediction only];


:

Pssm-ID: 440899 [Multi-domain]  Cd Length: 464  Bit Score: 571.70  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371   4 SKKKKTFNFPSAFTILFAILILAVGLTWVIPSGSYSKLTynstdnvfvvkaygvddktypattdtldnlnikiklsnftE 83
Cdd:COG1288    5 KKKKKKFKFPHAYVILFIIIVLAAILTWIIPAGEYDRVE----------------------------------------D 44
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  84 GvikKPIAIPGTYQRVEQHHKGIEDITKSMVEGTIEAVDVMVFIFVLGGMIGVINRTGSFNAGLMALVKKTKGNEFFIVF 163
Cdd:COG1288   45 G---RTVVVPGSYHYVEQNPQGLFDIFTAPIKGLVEAADIIFFILIIGGAFGVINKTGAIDAGIGALVRKLKGKEKLLIP 121
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 164 CVSVLMVLGGTTCGIEEEAVAFYPILVPVFLALGYDAIVCVGAIFLAASMGTAFSTINPFSVVIASNAAGIQFTEGIGFR 243
Cdd:COG1288  122 VLMLLFALGGTTFGMAEETIAFYPILVPLAIALGYDAITGVAIIFLGAGIGFAASTINPFTVGIAQGIAGLPLFSGIGLR 201
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 244 ALGLVLGATCVIAYLYWYCKKIKADPSFSYTYDDREEFRQRYMKnfDPNTTIPFSARRKLILTLFCISFPIMIWGVMVGG 323
Cdd:COG1288  202 LVIFVVFTLIAIIYVMRYAKKVKKDPEKSLVYDDDEEFRKRFLK--DDDEDPEFTGRHKLVLLVFALGFVIMIYGVLKLG 279
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 324 WWFPQMAASFLAITIIIMFISGLSEKDVVESFTEGASELVGVSLIIGLARGVNLVLEQGMISDTILDYMSNVVSGMPGSV 403
Cdd:COG1288  280 WYFPEMAALFLVMGIVAGIIGGLSENKIAEAFVKGAKDLLGGALIIGLARGILVIMEDGKILDTILYGLSNLLSGLPPVL 359
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 404 FILGQLVVFIFLGLIVPSSSGLAVLSMPIMAPLADSVGIPRDIVVSAYNWGQYAMLFLAPT-GLVLVTLQMLHIPFDRWV 482
Cdd:COG1288  360 FAIGMFIVQSLLNFFVPSGSGQAALTMPIMAPLADLVGVTRQTAVLAFQFGDGLTNLITPTsGVLMATLAIAGVPYDKWL 439
                        490       500
                 ....*....|....*....|....*
gi 499591371 483 KFVMPMIGCLLLIGSILLVVQVSLY 507
Cdd:COG1288  440 KFVWPLFLILFLLAIVFLIIAVLIG 464
 
Name Accession Description Interval E-value
YfcC COG1288
Predicted membrane transporter YfcC, affects glyoxylate shunt [General function prediction ...
4-507 0e+00

Predicted membrane transporter YfcC, affects glyoxylate shunt [General function prediction only];


Pssm-ID: 440899 [Multi-domain]  Cd Length: 464  Bit Score: 571.70  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371   4 SKKKKTFNFPSAFTILFAILILAVGLTWVIPSGSYSKLTynstdnvfvvkaygvddktypattdtldnlnikiklsnftE 83
Cdd:COG1288    5 KKKKKKFKFPHAYVILFIIIVLAAILTWIIPAGEYDRVE----------------------------------------D 44
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  84 GvikKPIAIPGTYQRVEQHHKGIEDITKSMVEGTIEAVDVMVFIFVLGGMIGVINRTGSFNAGLMALVKKTKGNEFFIVF 163
Cdd:COG1288   45 G---RTVVVPGSYHYVEQNPQGLFDIFTAPIKGLVEAADIIFFILIIGGAFGVINKTGAIDAGIGALVRKLKGKEKLLIP 121
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 164 CVSVLMVLGGTTCGIEEEAVAFYPILVPVFLALGYDAIVCVGAIFLAASMGTAFSTINPFSVVIASNAAGIQFTEGIGFR 243
Cdd:COG1288  122 VLMLLFALGGTTFGMAEETIAFYPILVPLAIALGYDAITGVAIIFLGAGIGFAASTINPFTVGIAQGIAGLPLFSGIGLR 201
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 244 ALGLVLGATCVIAYLYWYCKKIKADPSFSYTYDDREEFRQRYMKnfDPNTTIPFSARRKLILTLFCISFPIMIWGVMVGG 323
Cdd:COG1288  202 LVIFVVFTLIAIIYVMRYAKKVKKDPEKSLVYDDDEEFRKRFLK--DDDEDPEFTGRHKLVLLVFALGFVIMIYGVLKLG 279
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 324 WWFPQMAASFLAITIIIMFISGLSEKDVVESFTEGASELVGVSLIIGLARGVNLVLEQGMISDTILDYMSNVVSGMPGSV 403
Cdd:COG1288  280 WYFPEMAALFLVMGIVAGIIGGLSENKIAEAFVKGAKDLLGGALIIGLARGILVIMEDGKILDTILYGLSNLLSGLPPVL 359
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 404 FILGQLVVFIFLGLIVPSSSGLAVLSMPIMAPLADSVGIPRDIVVSAYNWGQYAMLFLAPT-GLVLVTLQMLHIPFDRWV 482
Cdd:COG1288  360 FAIGMFIVQSLLNFFVPSGSGQAALTMPIMAPLADLVGVTRQTAVLAFQFGDGLTNLITPTsGVLMATLAIAGVPYDKWL 439
                        490       500
                 ....*....|....*....|....*
gi 499591371 483 KFVMPMIGCLLLIGSILLVVQVSLY 507
Cdd:COG1288  440 KFVWPLFLILFLLAIVFLIIAVLIG 464
DcuC pfam03606
C4-dicarboxylate anaerobic carrier;
17-504 7.05e-161

C4-dicarboxylate anaerobic carrier;


Pssm-ID: 427395 [Multi-domain]  Cd Length: 454  Bit Score: 464.10  E-value: 7.05e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371   17 TILFAILILAVGLTWVIPSGSYSKLTynstdnvfvvkaygvddktypattdtldnlnikiKLSNFTEGVIKKPIAIPGTY 96
Cdd:pfam03606   1 GILFIIAVGYAILTWYIPAGVLAKAG----------------------------------IILGIYSGALGKPEVLPFTY 46
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371   97 QRVEQHHKGIEDITKSMVEGTIEAVDVMVFIFVLGGMIGVINRTGSFNAGLMALVKKTKGNEFFIVFCVSVLMVLGGTTC 176
Cdd:pfam03606  47 KSTGYLMLDLPIEEYVKGLGMSRAVDLGMFILVLGGFAGYMMRTGAIDAGVKALSKPLKGIESPYILLLAAYFSLGGTVL 126
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  177 GIEEEAVAFYPILVPVFLALGYDAIVCVGAIFLAASMGTAFSTINPFSVVIASNAAGIQFTEGIGFRALGLVLGATCVIA 256
Cdd:pfam03606 127 GMSEETVAFMPILFPIMVALGYDSRTGAAAICAATAVGFLASTSNPFDVVIAAQIAGLPLLDGFGLRLLPWVIITIISIA 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  257 YLYWYCKKIKADPsfsyTYDDREEFRQRYMKNFDPNTTIPFsaRRKLILTLFCISFPIMIWG--VMVGGWWFPQMAASFL 334
Cdd:pfam03606 207 YLHFYAQKIKDDP----VYSEKDESDQHEMDEQSEVTTIFS--RPKVYLILPVLPFILMLWGfgVIVNGWWFPEIAVLFL 280
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  335 AITIIIMFI---SGLSEKDVVESFTEGASELVGVSLIIGLARGVNLVLEQGMISDTILDYMSNVVSGMPGSVFILGQLVV 411
Cdd:pfam03606 281 AMGIIIGFIrkfNGLGENEIVEAFYEGAADLLGFALVVGLARGVGLFAQGGMIIDTILNLISGAISGLPGILFILVMLLI 360
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  412 FIFLGLIVPSSSGLAVLSMPIMAPLADSVGIPRDIVVSAYNWGQYAMLFLAPT-GLVLVTLQMLHIPFDRWVKFVMPMIG 490
Cdd:pfam03606 361 QALAAFVVPSGSGPAYLTMPLMAPLADLVGIPRAVLVLAMQFASGLGRIISPTsGVVVATLGMARISPFTWVKFVAPPVA 440
                         490
                  ....*....|....
gi 499591371  491 CLLLIGSILLVVQV 504
Cdd:pfam03606 441 VGLIIVIIVTIIAV 454
PRK11588 PRK11588
putative basic amino acid antiporter YfcC;
2-504 4.95e-80

putative basic amino acid antiporter YfcC;


Pssm-ID: 236934 [Multi-domain]  Cd Length: 506  Bit Score: 258.39  E-value: 4.95e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371   2 DASKKKKTFNFPSAFTILFAILILAVGLTWVIPSGSYSkltynsTDNVfvvkAYGVDDKTYpaTTDTLDNLNIKIKLSNF 81
Cdd:PRK11588   5 TESKPTRRWAMPDTLVIIFFVAILAALATYVVPVGMFD------SQEV----QYQVDGQTK--TRKVVDPHSFRILTDEA 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  82 TEGViKKPIAIPGTYQrveqhhkGIEDITKSMVEGTIE------AVDVMVFIFVLGGMIGVINRTGSFNAGLMALVKKTK 155
Cdd:PRK11588  73 GEPE-YHRVQLFTTGD-------ERPGLMNFPFEGLTSgskwgtAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRKTR 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 156 GNEFFIVFCVSVLMVLGGTTCGIEEEAVAFYPILVPVFLALGYDAIVCVGAIFLAASMGTAFSTINPFSVVIASNAAGIQ 235
Cdd:PRK11588 145 GNEILFIPVLFILFSLGGAVFGMGEEAIAFAIIIAPLMVRLGYDSITTVLVTYVATQIGFATSWMNPFSVAIAQGIAGVP 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 236 FTEGIGFRALGLVLGATCVIAYLYWYCKKIKADPSFSYTYDDREEFRQrymkNFDPNTTIPFSARRKLILTLFCISFPIM 315
Cdd:PRK11588 225 VLSGSGLRIVMWVIFTLIGLIFTMVYASRVKKNPLLSRVHESDRFFRE----KQADVEQRPFTFGDWLVLLVLTAVMVWV 300
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 316 IWGVMVGGWWFPQMAASFLAITIIIMFI------SGLSEKDVVESFTEGASELVGVSLIIGLARGVNLVL-----EQGMI 384
Cdd:PRK11588 301 IWGVVVNAWFIPEIASQFFTMGLVIGLIgvvfrlNGMTVNTMASSFTEGARMMLAPALLVGFAKGILLLLgggepGDPSV 380
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 385 SDTILDYMSNVVSGMPGSVFILGQLVVFIFLGLIVPSSSGLAVLSMPIMAPLADSVGIPRDIVVSAYNWGQYAMLFLAPT 464
Cdd:PRK11588 381 LNTILNSAGGAISGLPDAVSAWFMLLFQSVFNFFVTSGSGQAALTMPLMAPLADLVGVNRQVAVLAFQLGDGFTNIIYPT 460
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|.
gi 499591371 465 GLVLV-TLQMLHIPFDRWVKFVMPMIGCLLLIGSILLVVQV 504
Cdd:PRK11588 461 SASLMaTLGVCRVDFGNWLKFIWRFLLLLFIMSSVVVIGAQ 501
ArsB_NhaD_permease cd00625
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ...
118-500 7.76e-03

Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.


Pssm-ID: 238344 [Multi-domain]  Cd Length: 396  Bit Score: 38.77  E-value: 7.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 118 IEAVDVMVFIFVLGGMI--GVINRTGSFN--AGLMALVKKTKGNEFFIVFCVS--VLMVLGGTTCgieeeAVAFYPILVP 191
Cdd:cd00625   34 LSAIDWETILLLFGMMIlsAALEETGLFDrlAAKLARASKGSRRLLLLLMLLTaaLSAFFSNDAT-----AVLLTPIVLA 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 192 VFLALGYDAIVC-VGAIFLAASMGTAFSTI-NPFSVVIASnAAGIQFTEGIGFRALGLVLGATCVIAYLYWYCKKIKADP 269
Cdd:cd00625  109 LLRKLGLSPPVPlLLALAFAANIGGAATPIgNPPNLIIAS-LSGLGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLLLP 187
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 270 SFSYTYDDREEFRQRymknfdpnttipFSARRKLILTLFCISFPIMIWGVMVGGWWFpqmaASFLAITIIIMFISGLSEK 349
Cdd:cd00625  188 DEDKLTVLAEPLPAR------------PLLKKFLLLALLLLLLFVLLFFFLIPLGLI----ALLGALLLLLLLVRGLDPE 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 350 DVVESFtegasELVGVSLIIGLargvnLVLEQGMISDTILDYMSNVVSGMPGSVFILGQLVVFIFLGLIVPSSSGLAvlS 429
Cdd:cd00625  252 EVLKSV-----DWGTLLFFAGL-----FVLVGALESTGLLEWLAELLVALVGLPPLAALLLIGLLSALLSNFISNVP--T 319
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499591371 430 MPIMAPLADSVGIPrDIVVSAYNWGQYAMLFLAPTG-----LVLVTL--QMLHIPFDRWVKFVMPMIGCLLLIGSILL 500
Cdd:cd00625  320 VALLLPIAASLAPP-EPAWLALALGSTLGGNLTLIGslanlIPLGAAenAGVGISFGEFLKVGLPLTLLSLVVSLLYL 396
 
Name Accession Description Interval E-value
YfcC COG1288
Predicted membrane transporter YfcC, affects glyoxylate shunt [General function prediction ...
4-507 0e+00

Predicted membrane transporter YfcC, affects glyoxylate shunt [General function prediction only];


Pssm-ID: 440899 [Multi-domain]  Cd Length: 464  Bit Score: 571.70  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371   4 SKKKKTFNFPSAFTILFAILILAVGLTWVIPSGSYSKLTynstdnvfvvkaygvddktypattdtldnlnikiklsnftE 83
Cdd:COG1288    5 KKKKKKFKFPHAYVILFIIIVLAAILTWIIPAGEYDRVE----------------------------------------D 44
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  84 GvikKPIAIPGTYQRVEQHHKGIEDITKSMVEGTIEAVDVMVFIFVLGGMIGVINRTGSFNAGLMALVKKTKGNEFFIVF 163
Cdd:COG1288   45 G---RTVVVPGSYHYVEQNPQGLFDIFTAPIKGLVEAADIIFFILIIGGAFGVINKTGAIDAGIGALVRKLKGKEKLLIP 121
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 164 CVSVLMVLGGTTCGIEEEAVAFYPILVPVFLALGYDAIVCVGAIFLAASMGTAFSTINPFSVVIASNAAGIQFTEGIGFR 243
Cdd:COG1288  122 VLMLLFALGGTTFGMAEETIAFYPILVPLAIALGYDAITGVAIIFLGAGIGFAASTINPFTVGIAQGIAGLPLFSGIGLR 201
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 244 ALGLVLGATCVIAYLYWYCKKIKADPSFSYTYDDREEFRQRYMKnfDPNTTIPFSARRKLILTLFCISFPIMIWGVMVGG 323
Cdd:COG1288  202 LVIFVVFTLIAIIYVMRYAKKVKKDPEKSLVYDDDEEFRKRFLK--DDDEDPEFTGRHKLVLLVFALGFVIMIYGVLKLG 279
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 324 WWFPQMAASFLAITIIIMFISGLSEKDVVESFTEGASELVGVSLIIGLARGVNLVLEQGMISDTILDYMSNVVSGMPGSV 403
Cdd:COG1288  280 WYFPEMAALFLVMGIVAGIIGGLSENKIAEAFVKGAKDLLGGALIIGLARGILVIMEDGKILDTILYGLSNLLSGLPPVL 359
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 404 FILGQLVVFIFLGLIVPSSSGLAVLSMPIMAPLADSVGIPRDIVVSAYNWGQYAMLFLAPT-GLVLVTLQMLHIPFDRWV 482
Cdd:COG1288  360 FAIGMFIVQSLLNFFVPSGSGQAALTMPIMAPLADLVGVTRQTAVLAFQFGDGLTNLITPTsGVLMATLAIAGVPYDKWL 439
                        490       500
                 ....*....|....*....|....*
gi 499591371 483 KFVMPMIGCLLLIGSILLVVQVSLY 507
Cdd:COG1288  440 KFVWPLFLILFLLAIVFLIIAVLIG 464
DcuC pfam03606
C4-dicarboxylate anaerobic carrier;
17-504 7.05e-161

C4-dicarboxylate anaerobic carrier;


Pssm-ID: 427395 [Multi-domain]  Cd Length: 454  Bit Score: 464.10  E-value: 7.05e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371   17 TILFAILILAVGLTWVIPSGSYSKLTynstdnvfvvkaygvddktypattdtldnlnikiKLSNFTEGVIKKPIAIPGTY 96
Cdd:pfam03606   1 GILFIIAVGYAILTWYIPAGVLAKAG----------------------------------IILGIYSGALGKPEVLPFTY 46
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371   97 QRVEQHHKGIEDITKSMVEGTIEAVDVMVFIFVLGGMIGVINRTGSFNAGLMALVKKTKGNEFFIVFCVSVLMVLGGTTC 176
Cdd:pfam03606  47 KSTGYLMLDLPIEEYVKGLGMSRAVDLGMFILVLGGFAGYMMRTGAIDAGVKALSKPLKGIESPYILLLAAYFSLGGTVL 126
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  177 GIEEEAVAFYPILVPVFLALGYDAIVCVGAIFLAASMGTAFSTINPFSVVIASNAAGIQFTEGIGFRALGLVLGATCVIA 256
Cdd:pfam03606 127 GMSEETVAFMPILFPIMVALGYDSRTGAAAICAATAVGFLASTSNPFDVVIAAQIAGLPLLDGFGLRLLPWVIITIISIA 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  257 YLYWYCKKIKADPsfsyTYDDREEFRQRYMKNFDPNTTIPFsaRRKLILTLFCISFPIMIWG--VMVGGWWFPQMAASFL 334
Cdd:pfam03606 207 YLHFYAQKIKDDP----VYSEKDESDQHEMDEQSEVTTIFS--RPKVYLILPVLPFILMLWGfgVIVNGWWFPEIAVLFL 280
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  335 AITIIIMFI---SGLSEKDVVESFTEGASELVGVSLIIGLARGVNLVLEQGMISDTILDYMSNVVSGMPGSVFILGQLVV 411
Cdd:pfam03606 281 AMGIIIGFIrkfNGLGENEIVEAFYEGAADLLGFALVVGLARGVGLFAQGGMIIDTILNLISGAISGLPGILFILVMLLI 360
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  412 FIFLGLIVPSSSGLAVLSMPIMAPLADSVGIPRDIVVSAYNWGQYAMLFLAPT-GLVLVTLQMLHIPFDRWVKFVMPMIG 490
Cdd:pfam03606 361 QALAAFVVPSGSGPAYLTMPLMAPLADLVGIPRAVLVLAMQFASGLGRIISPTsGVVVATLGMARISPFTWVKFVAPPVA 440
                         490
                  ....*....|....
gi 499591371  491 CLLLIGSILLVVQV 504
Cdd:pfam03606 441 VGLIIVIIVTIIAV 454
PRK11588 PRK11588
putative basic amino acid antiporter YfcC;
2-504 4.95e-80

putative basic amino acid antiporter YfcC;


Pssm-ID: 236934 [Multi-domain]  Cd Length: 506  Bit Score: 258.39  E-value: 4.95e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371   2 DASKKKKTFNFPSAFTILFAILILAVGLTWVIPSGSYSkltynsTDNVfvvkAYGVDDKTYpaTTDTLDNLNIKIKLSNF 81
Cdd:PRK11588   5 TESKPTRRWAMPDTLVIIFFVAILAALATYVVPVGMFD------SQEV----QYQVDGQTK--TRKVVDPHSFRILTDEA 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  82 TEGViKKPIAIPGTYQrveqhhkGIEDITKSMVEGTIE------AVDVMVFIFVLGGMIGVINRTGSFNAGLMALVKKTK 155
Cdd:PRK11588  73 GEPE-YHRVQLFTTGD-------ERPGLMNFPFEGLTSgskwgtAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRKTR 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 156 GNEFFIVFCVSVLMVLGGTTCGIEEEAVAFYPILVPVFLALGYDAIVCVGAIFLAASMGTAFSTINPFSVVIASNAAGIQ 235
Cdd:PRK11588 145 GNEILFIPVLFILFSLGGAVFGMGEEAIAFAIIIAPLMVRLGYDSITTVLVTYVATQIGFATSWMNPFSVAIAQGIAGVP 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 236 FTEGIGFRALGLVLGATCVIAYLYWYCKKIKADPSFSYTYDDREEFRQrymkNFDPNTTIPFSARRKLILTLFCISFPIM 315
Cdd:PRK11588 225 VLSGSGLRIVMWVIFTLIGLIFTMVYASRVKKNPLLSRVHESDRFFRE----KQADVEQRPFTFGDWLVLLVLTAVMVWV 300
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 316 IWGVMVGGWWFPQMAASFLAITIIIMFI------SGLSEKDVVESFTEGASELVGVSLIIGLARGVNLVL-----EQGMI 384
Cdd:PRK11588 301 IWGVVVNAWFIPEIASQFFTMGLVIGLIgvvfrlNGMTVNTMASSFTEGARMMLAPALLVGFAKGILLLLgggepGDPSV 380
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 385 SDTILDYMSNVVSGMPGSVFILGQLVVFIFLGLIVPSSSGLAVLSMPIMAPLADSVGIPRDIVVSAYNWGQYAMLFLAPT 464
Cdd:PRK11588 381 LNTILNSAGGAISGLPDAVSAWFMLLFQSVFNFFVTSGSGQAALTMPLMAPLADLVGVNRQVAVLAFQLGDGFTNIIYPT 460
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|.
gi 499591371 465 GLVLV-TLQMLHIPFDRWVKFVMPMIGCLLLIGSILLVVQV 504
Cdd:PRK11588 461 SASLMaTLGVCRVDFGNWLKFIWRFLLLLFIMSSVVVIGAQ 501
CitT COG0471
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
182-448 1.46e-06

Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];


Pssm-ID: 440239 [Multi-domain]  Cd Length: 369  Bit Score: 50.54  E-value: 1.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 182 AVAFYPILVPVFLALGYDAIVCVG-----AIFLAASMGTAFSTINPFSVVIASNAAGIQFTEGIGFR---ALGLVLGATC 253
Cdd:COG0471   55 AAMMLPIALSIAAALGSEKRSKFGsalllPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIPISFFewmLVGLPVALVG 134
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 254 VIAYLYWYCKKIKadPSFSYTYDDREEFRQRYmknfdpNTTIPFSARRKLILTLFCIsfpiMIWGVMVGGWWFPQMAASF 333
Cdd:COG0471  135 LLLLWLVLYRLLP--PEIKEVPGSKEVIREEL------AELGPLSRREKIALAIFAL----TVLLWITGSLHGIPIAVVA 202
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 334 LAItIIIMFISG-LSEKDVVESFTEGASELVGVSLIIGLArgvnlvLEQGMISDTILDYMSNVVSGMPGSVFILGQLVVF 412
Cdd:COG0471  203 LLG-AVLLLLTGvLTWKDAYKSIPWGVLLLFGGGLALGAA------LEKTGLAAWLADALLPLLGGLSPLLLLLLLALLT 275
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 499591371 413 IFLGLIVpSSSGLAVLSMPIMAPLADSVGIPRDIVV 448
Cdd:COG0471  276 LLLTEFA-SNTATAALLLPIAISLAQALGVNPLPLA 310
GntT COG2610
H+/gluconate symporter GntT or related permease, GntP/DsdX family [Carbohydrate transport and ...
105-450 4.85e-06

H+/gluconate symporter GntT or related permease, GntP/DsdX family [Carbohydrate transport and metabolism];


Pssm-ID: 442022 [Multi-domain]  Cd Length: 440  Bit Score: 48.96  E-value: 4.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 105 GIEDITKSMVEG---TIEAVdvmVFIFVLGGMIG-VINRTGSFNAGLMALVKKTKGNEffivfcVSVLMVLGGTTCGI-- 178
Cdd:COG2610   43 PLAKIVTSIMTGfggTLGSI---GLVIGLGAMLGkLLEDSGAAERIADTIIKKFGEKR------APLALVLAGFILGIpv 113
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 179 --EEEAVAFYPILVPVFLALGYDAIVCVGAIFLAASMGTAFSTINPfSVVIASNAAGIQFTEGIGFRALGLVLGATCVIA 256
Cdd:COG2610  114 ffDVGFVILAPLAFSLARRAGISKLLIGLALAAGLSTTHMLVPPTP-GPLAAAGILGADLGAVILLGLIVAIPALIVGYL 192
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 257 YLYWYCKKIKADPsfsytyddREEFRQRYMKNFDPNTTIPfsarrKLILTLFCISFPIMI-----WGVMVGGWWFPQMAA 331
Cdd:COG2610  193 YAKWLGKKAPVPA--------PEGLAGEEDEEEEDDEELP-----SFGLALLPILLPIVLillgtIADLLPKDSALVQVL 259
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 332 SFLAITIIIMFIS----------GLSEKDVVESFTEGASELVGVSLIIGLARGVNLVLEQGMISDTILDYMSnvvsGMPG 401
Cdd:COG2610  260 AFIGDPIIALLIGvlvailllrrGLSREELMKILNEGLKPAGLILLITGAGGAFGAVLAASGIGDAIADALS----GLGL 335
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*....
gi 499591371 402 SVFILGQLVVFIfLGLIVPSSSGLAVLSMPIMAPLADSVGIPRDIVVSA 450
Cdd:COG2610  336 PPLLLAFLIAAL-LRGATGSATVAMITAAGILAPLLLALGVSPELLVLA 383
DctM pfam06808
Tripartite ATP-independent periplasmic transporter, DctM component; This family contains a ...
164-498 2.20e-03

Tripartite ATP-independent periplasmic transporter, DctM component; This family contains a diverse range of predicted transporter proteins. Including the DctM subunit of the bacterial and archaeal TRAP C4-dicarboxylate transport (Dct) system permease. In general, C4-dicarboxylate transport systems allow C4-dicarboxylates like succinate, fumarate, and malate to be taken up. TRAP C4-dicarboxylate carriers are secondary carriers that use an electrochemical H+ gradient as the driving force for transport. DctM is an integral membrane protein that is one of the constituents of TRAP carriers. Note that many family members are hypothetical proteins.


Pssm-ID: 284275 [Multi-domain]  Cd Length: 413  Bit Score: 40.32  E-value: 2.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  164 CVSVLMVLGGTTCGIEEEAVAFYPILVPVFLALGYDAIVCVGAIFLAASMGTAFSTINPFSVVIASNAA---GIQFTEGI 240
Cdd:pfam06808  93 SVVGSALFGMISGSAVANVATVGSVTIPAMKRSGYPPSFAAAVEAASSTLGQIIPPSIGLIAFGMAFAGvsiGDLFMAGI 172
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  241 gfrALGLVLGATCVIA-YLYWYCKKIKADPSFSytyddreefrqrymknfdpnttiPFSARRKLILTLFCISFPIMIWGV 319
Cdd:pfam06808 173 ---IPGLLYAVGLMLAvYIYAKRRNLPGTPRAL-----------------------LPRAGQALKDGWWALLLPFIILIG 226
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  320 MVGGWWFPQMA---ASFLAITIIIMFISGLSEKDVVESFTEGASELVGVSLIIGLARGVNLVLEQGMISDTILDYMSNVV 396
Cdd:pfam06808 227 ILLGIFTPTEAgayAVVYALLIGVLVYRRLTLEEVAAALLQTAKTTAAVLFILAAAGIFAGLLTITGVPFKLSDWLLSLG 306
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  397 SGMPGsvFILGQLVVFIFLGLIVPSSSGLAVLSmPIMAPLADSVGI-PRDIVVSAYNWGQYAmLFLAPTGLVL-VTLQML 474
Cdd:pfam06808 307 GGNLL--FLILVNLLCLVLGMFLDPTAAIIILV-PILAPAAAQLGIdPIHFGVVIVYNGSIG-LITPPVGLALfVAAGIA 382
                         330       340
                  ....*....|....*....|....*...
gi 499591371  475 HIPFDRWVK----FVMPMIGCLLLIGSI 498
Cdd:pfam06808 383 KVSFEEVVKgvvpFLFVLVPALVLIISV 410
CitMHS pfam03600
Citrate transporter;
115-442 4.75e-03

Citrate transporter;


Pssm-ID: 460985 [Multi-domain]  Cd Length: 342  Bit Score: 39.22  E-value: 4.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  115 EGTIEAVDVMVFIFVLGGMI--GVINRTGSFNAGLMALVKKTKGNEFFIVFCVSVL-----MVLGGTTCgieeeAVAFYP 187
Cdd:pfam03600  31 EEALSGIDSPTILLLLGMMIigAILERTGLFDRLALKLLRLAGGKPRRLLVALMLAtallsAFLSNDGT-----VLIMIP 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  188 ILVPVFLALGYDAIVCVGAIFLAASMGTAFSTI-NPFSVVIASnAAGIQFTEGIGFRALGLVLGATCV-IAYLYWYCKKI 265
Cdd:pfam03600 106 IVLALARRLGLPPSPLLIALAFAANIGGTATPIgDPPNIIIAS-ALGLSFGDFGFFMFPPVGVALLLVgLLPLLLIFRKL 184
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  266 KADpsfsytyddreefrqRYMKNFDPNTTIPFSARRKLILTLFCisfpIMIWGVMVGGWWFPQMAASFLAITIIIMFISG 345
Cdd:pfam03600 185 LPV---------------RKEEEAELEELRKRAIKDKLLLAISA----LVLALVILGFLLLSVLALAGALLLLLTGVLDP 245
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371  346 LSEKDVVESFTegaselvgVSLIIGLargvnLVLEQGMISDTILDYMSNVVSGMPGSVFILGQLVVFIFLGLIVPSSSGL 425
Cdd:pfam03600 246 EEALKAVDWST--------LLFFAGL-----FILVGALEKTGLADALADALGGLSGLLVALALILWLSALLSAFISNVPT 312
                         330
                  ....*....|....*..
gi 499591371  426 AVLSMPIMAPLADSVGI 442
Cdd:pfam03600 313 AALMAPIIVGMAPAAGL 329
ArsB_NhaD_permease cd00625
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ...
118-500 7.76e-03

Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.


Pssm-ID: 238344 [Multi-domain]  Cd Length: 396  Bit Score: 38.77  E-value: 7.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 118 IEAVDVMVFIFVLGGMI--GVINRTGSFN--AGLMALVKKTKGNEFFIVFCVS--VLMVLGGTTCgieeeAVAFYPILVP 191
Cdd:cd00625   34 LSAIDWETILLLFGMMIlsAALEETGLFDrlAAKLARASKGSRRLLLLLMLLTaaLSAFFSNDAT-----AVLLTPIVLA 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 192 VFLALGYDAIVC-VGAIFLAASMGTAFSTI-NPFSVVIASnAAGIQFTEGIGFRALGLVLGATCVIAYLYWYCKKIKADP 269
Cdd:cd00625  109 LLRKLGLSPPVPlLLALAFAANIGGAATPIgNPPNLIIAS-LSGLGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLLLP 187
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 270 SFSYTYDDREEFRQRymknfdpnttipFSARRKLILTLFCISFPIMIWGVMVGGWWFpqmaASFLAITIIIMFISGLSEK 349
Cdd:cd00625  188 DEDKLTVLAEPLPAR------------PLLKKFLLLALLLLLLFVLLFFFLIPLGLI----ALLGALLLLLLLVRGLDPE 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499591371 350 DVVESFtegasELVGVSLIIGLargvnLVLEQGMISDTILDYMSNVVSGMPGSVFILGQLVVFIFLGLIVPSSSGLAvlS 429
Cdd:cd00625  252 EVLKSV-----DWGTLLFFAGL-----FVLVGALESTGLLEWLAELLVALVGLPPLAALLLIGLLSALLSNFISNVP--T 319
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499591371 430 MPIMAPLADSVGIPrDIVVSAYNWGQYAMLFLAPTG-----LVLVTL--QMLHIPFDRWVKFVMPMIGCLLLIGSILL 500
Cdd:cd00625  320 VALLLPIAASLAPP-EPAWLALALGSTLGGNLTLIGslanlIPLGAAenAGVGISFGEFLKVGLPLTLLSLVVSLLYL 396
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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