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Conserved domains on  [gi|499622083|ref|WP_011302817|]
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MULTISPECIES: foldase protein PrsA [Staphylococcus]

Protein Classification

foldase protein PrsA( domain architecture ID 13439506)

foldase protein PrsA plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins

CATH:  3.10.50.40
EC:  5.2.1.8
Gene Ontology:  GO:0003755|GO:0006457
PubMed:  12871165

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 145-285 9.76e-29

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 108.12  E-value: 9.76e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 145 SHILIKVKENKDDKEglsdkeAKAKAEKIQKEVEKHpDKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLK 224
Cdd:COG0760   12 SHILVKVPPSEDRAK------AEAKAEELLAQLKAG-ADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALK 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499622083 225 EGKVSDVVKTDYGYHIIK-----ADKENDFDKEKGKLKAQLIQTKIQKdpklltdAYKELLDEYKV 285
Cdd:COG0760   85 PGEISGPVKTQFGYHIIKvedrrPAETPPFEEVKQQIRQELFQQALEA-------WLEELRKKAKI 143
Rotamase_2 super family cl29122
PPIC-type PPIASE domain;
5-305 3.65e-25

PPIC-type PPIASE domain;


The actual alignment was detected with superfamily member PRK03095:

Pssm-ID: 452928 [Multi-domain]  Cd Length: 287  Bit Score: 102.38  E-value: 3.65e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083   5 KKVLLPVTASALL-LGACGNSATDSkedtIISSKAGDVKVEDVMNKMGDEQIANTSFSIMLNKLLADKYKddVNTKDIDK 83
Cdd:PRK03095   2 KKAMLALAATSVIaLSACGTSSSDK----IVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYK--VEDKEVDK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  84 EVEKEQKQYGgkDQFESMLKQQKMSIGDYKEQKKLQAYQKELLNDkvSMSDKEIKENTK---KGSHILIKvkenkddkeg 160
Cdd:PRK03095  76 KYDEMKKQYG--DQFDTLLKQQGIKEETLKTGVRAQLAQEKAIEK--TITDKELKDNYKpeiKASHILVK---------- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 161 lsdkeAKAKAEKIQKEVEKHpDKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLKEGKVSDVVKTDYGYHI 240
Cdd:PRK03095 142 -----DEATAKKVKEELGQG-KSFEELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHI 215

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499622083 241 IKA----DKENDFDKEKGKLKAQLIQTKIQkDPKLLTDAYKELLDEYKVDYKDRDIKKAIEDSILDPEK 305
Cdd:PRK03095 216 IKVtdikEPEKSFEQSKADIKKELVQKKAQ-DGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKADAKK 283
 
Name Accession Description Interval E-value
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 145-285 9.76e-29

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 108.12  E-value: 9.76e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 145 SHILIKVKENKDDKEglsdkeAKAKAEKIQKEVEKHpDKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLK 224
Cdd:COG0760   12 SHILVKVPPSEDRAK------AEAKAEELLAQLKAG-ADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALK 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499622083 225 EGKVSDVVKTDYGYHIIK-----ADKENDFDKEKGKLKAQLIQTKIQKdpklltdAYKELLDEYKV 285
Cdd:COG0760   85 PGEISGPVKTQFGYHIIKvedrrPAETPPFEEVKQQIRQELFQQALEA-------WLEELRKKAKI 143
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 146-245 1.15e-28

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 106.23  E-value: 1.15e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  146 HILIKVKENKDDKEglsdKEAKAKAEKIQKEVEKHPDKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLKE 225
Cdd:pfam00639   1 HILIKTPEASERDR----AEAKAKAEEILEQLKSGEDSFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKP 76

                          90       100
                  ....*....|....*....|
gi 499622083  226 GKVSDVVKTDYGYHIIKADK 245
Cdd:pfam00639  77 GEISGPVETRFGFHIIKLTD 96
prsA PRK03095
peptidylprolyl isomerase PrsA;
5-305 3.65e-25

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 102.38  E-value: 3.65e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083   5 KKVLLPVTASALL-LGACGNSATDSkedtIISSKAGDVKVEDVMNKMGDEQIANTSFSIMLNKLLADKYKddVNTKDIDK 83
Cdd:PRK03095   2 KKAMLALAATSVIaLSACGTSSSDK----IVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYK--VEDKEVDK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  84 EVEKEQKQYGgkDQFESMLKQQKMSIGDYKEQKKLQAYQKELLNDkvSMSDKEIKENTK---KGSHILIKvkenkddkeg 160
Cdd:PRK03095  76 KYDEMKKQYG--DQFDTLLKQQGIKEETLKTGVRAQLAQEKAIEK--TITDKELKDNYKpeiKASHILVK---------- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 161 lsdkeAKAKAEKIQKEVEKHpDKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLKEGKVSDVVKTDYGYHI 240
Cdd:PRK03095 142 -----DEATAKKVKEELGQG-KSFEELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHI 215

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499622083 241 IKA----DKENDFDKEKGKLKAQLIQTKIQkDPKLLTDAYKELLDEYKVDYKDRDIKKAIEDSILDPEK 305
Cdd:PRK03095 216 IKVtdikEPEKSFEQSKADIKKELVQKKAQ-DGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKADAKK 283
prsA PRK03002
peptidylprolyl isomerase PrsA;
14-293 7.72e-20

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 87.68  E-value: 7.72e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  14 SALLLGACGNSatdSKEDTIISSKAGDVKVEDVMNKMGDEQIANTSFSIMLNKLLADKYKddVNTKDIDKEVEKEQKQYG 93
Cdd:PRK03002  14 SILMLSACGQK---NSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYK--VSDDDVDKEVQKAKSQYG 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  94 gkDQFESMLKQQKMSI-GDYKEQKKLQAYQKELLndKVSMSDKEIKENTK---KGSHILIKVKEnkddkeglsdkeakaK 169
Cdd:PRK03002  89 --DQFKNVLKNNGLKDeADFKNQIKFKLAMNEAI--KKSVTEKDVKDHYKpeiKASHILVSDEN---------------E 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 170 AEKIQKEVEKHPdKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLKEGKVSDVVKTDYGYHIIKADKEND- 248
Cdd:PRK03002 150 AKEIKKKLDAGA-SFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNGYHIIKLTDKKDl 228

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 499622083 249 --FDKEKGKLKAQLIQTKIqKDPKLLTDAYKELLDEYKVDYKDRDIK 293
Cdd:PRK03002 229 kpYDEVKDSIRKNLEEERT-ADPIFGKKLLQSELKKANIKINDSELE 274
 
Name Accession Description Interval E-value
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 145-285 9.76e-29

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 108.12  E-value: 9.76e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 145 SHILIKVKENKDDKEglsdkeAKAKAEKIQKEVEKHpDKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLK 224
Cdd:COG0760   12 SHILVKVPPSEDRAK------AEAKAEELLAQLKAG-ADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALK 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499622083 225 EGKVSDVVKTDYGYHIIK-----ADKENDFDKEKGKLKAQLIQTKIQKdpklltdAYKELLDEYKV 285
Cdd:COG0760   85 PGEISGPVKTQFGYHIIKvedrrPAETPPFEEVKQQIRQELFQQALEA-------WLEELRKKAKI 143
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 146-245 1.15e-28

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 106.23  E-value: 1.15e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  146 HILIKVKENKDDKEglsdKEAKAKAEKIQKEVEKHPDKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLKE 225
Cdd:pfam00639   1 HILIKTPEASERDR----AEAKAKAEEILEQLKSGEDSFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKP 76

                          90       100
                  ....*....|....*....|
gi 499622083  226 GKVSDVVKTDYGYHIIKADK 245
Cdd:pfam00639  77 GEISGPVETRFGFHIIKLTD 96
prsA PRK03095
peptidylprolyl isomerase PrsA;
5-305 3.65e-25

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 102.38  E-value: 3.65e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083   5 KKVLLPVTASALL-LGACGNSATDSkedtIISSKAGDVKVEDVMNKMGDEQIANTSFSIMLNKLLADKYKddVNTKDIDK 83
Cdd:PRK03095   2 KKAMLALAATSVIaLSACGTSSSDK----IVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYK--VEDKEVDK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  84 EVEKEQKQYGgkDQFESMLKQQKMSIGDYKEQKKLQAYQKELLNDkvSMSDKEIKENTK---KGSHILIKvkenkddkeg 160
Cdd:PRK03095  76 KYDEMKKQYG--DQFDTLLKQQGIKEETLKTGVRAQLAQEKAIEK--TITDKELKDNYKpeiKASHILVK---------- 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 161 lsdkeAKAKAEKIQKEVEKHpDKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLKEGKVSDVVKTDYGYHI 240
Cdd:PRK03095 142 -----DEATAKKVKEELGQG-KSFEELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHI 215

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499622083 241 IKA----DKENDFDKEKGKLKAQLIQTKIQkDPKLLTDAYKELLDEYKVDYKDRDIKKAIEDSILDPEK 305
Cdd:PRK03095 216 IKVtdikEPEKSFEQSKADIKKELVQKKAQ-DGEFMNDLMMKEIKKADVKVDDKDLKDLFEEKKADAKK 283
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 132-243 8.01e-21

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 85.88  E-value: 8.01e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  132 MSDKEIKENTKKGSHILIKVKENkddkEGLSDKEAKAKAEKIqKEVEKHPDKFGEIAKKESMDKASAKKDGSLGYVVKGQ 211
Cdd:pfam13616   6 LVDKKSAPDSVKASHILISYSQA----VSRTEEEAKAKADSL-LAALKNGADFAALAKTYSDDPASKNNGGDLGWFTKGQ 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 499622083  212 MEDKFEKALFKLKEGKVSDVVKTDYGYHIIKA 243
Cdd:pfam13616  81 MVKEFEDAVFSLKVGEISGVVKTQFGFHIIKV 112
prsA PRK04405
peptidylprolyl isomerase; Provisional
 1-298 1.13e-20

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 90.23  E-value: 1.13e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083   1 MKTFKKVLLPVTASALL---LGACGNSATdskedTIISSKAGDVKVEDVMNKMGDEQIANTSFSIM-LNKLLADKYKDDV 76
Cdd:PRK04405   1 MKKKMKKWALAAASAGLalsLAGCSSNQA-----TVATYSGGKITQSQYYKEMKQSSAGKTVLANMiIYRALEKQYGKKV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  77 NTKDIDKEVEKEQKQYGgkDQFESMLKQQKMSIGDYKEQKKLQAYQKELLNDKVSMSDKEIKENTKKG------SHILIk 150
Cdd:PRK04405  76 STKKVDKQYNSYKKQYG--SSFDSVLSQNGMTTSSFKQNLRTNLLSEAALKKLKKVTNSQLKKAWKSYqpkvtvQHILV- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 151 vkenkddkeglsdkEAKAKAEKIQKEVEKHPDkFGEIAKKESMDKASAKKDGSLGYV--VKGQMEDKFEKALFKLKEGKV 228
Cdd:PRK04405 153 --------------SKKSTAETVIKKLKDGKD-FAKLAKKYSTDTATKNKGGKLSAFdsTDTTLDSTFKTAAFKLKNGEY 217

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499622083 229 SDV-VKTDYGYHIIKADK---ENDFDKEKGKLKAQLIQTKIQkDPKLLTDAYKELLDEYKVDYKDRDIKKAIED 298
Cdd:PRK04405 218 TTTpVKTTYGYEVIKMIKhpaKGTFSDHKKALTKQIYAKWAS-DSSVMQRVISKVLKKANVSIKDKDLKDALSS 290
prsA PRK03002
peptidylprolyl isomerase PrsA;
14-293 7.72e-20

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 87.68  E-value: 7.72e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  14 SALLLGACGNSatdSKEDTIISSKAGDVKVEDVMNKMGDEQIANTSFSIMLNKLLADKYKddVNTKDIDKEVEKEQKQYG 93
Cdd:PRK03002  14 SILMLSACGQK---NSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYK--VSDDDVDKEVQKAKSQYG 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  94 gkDQFESMLKQQKMSI-GDYKEQKKLQAYQKELLndKVSMSDKEIKENTK---KGSHILIKVKEnkddkeglsdkeakaK 169
Cdd:PRK03002  89 --DQFKNVLKNNGLKDeADFKNQIKFKLAMNEAI--KKSVTEKDVKDHYKpeiKASHILVSDEN---------------E 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 170 AEKIQKEVEKHPdKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLKEGKVSDVVKTDYGYHIIKADKEND- 248
Cdd:PRK03002 150 AKEIKKKLDAGA-SFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNGYHIIKLTDKKDl 228

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 499622083 249 --FDKEKGKLKAQLIQTKIqKDPKLLTDAYKELLDEYKVDYKDRDIK 293
Cdd:PRK03002 229 kpYDEVKDSIRKNLEEERT-ADPIFGKKLLQSELKKANIKINDSELE 274
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 145-242 2.87e-19

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 82.00  E-value: 2.87e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 145 SHILIK-------VKENKDDKEGLSDKEAKAKAEKIQKEVEKHPDKFGEIAKKESmDKASAKKDGSLGYVVKGQMEDKFE 217
Cdd:PTZ00356   9 AHLLIKhtgsrnpVSRRTGKPVTRSKEEAIKELAKWREQIVSGEKTFEEIARQRS-DCGSAAKGGDLGFFGRGQMQKPFE 87

                         90       100
                 ....*....|....*....|....*
gi 499622083 218 KALFKLKEGKVSDVVKTDYGYHIIK 242
Cdd:PTZ00356  88 DAAFALKVGEISDIVHTDSGVHIIL 112
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 15-297 9.59e-19

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 84.64  E-value: 9.59e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  15 ALLLGACGNSatdskeDTIISSKAGDVKVEDVMNKMGDEQIANTSFSIMLNKLLADKYKddVNTKDIDKEVEKEQKQYGg 94
Cdd:PRK02998  16 VLALSACGSS------DNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKYK--VSDEEAKKQVEEAKDKMG- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  95 kDQFESMLKQQKMSIGD-YKEQKKLQ-AYQKELlndKVSMSDKEIKENTK---KGSHILIKvkenkddkeglSDKEAKAK 169
Cdd:PRK02998  87 -DNFKSTLEQVGLKNEDeLKEKMKPEiAFEKAI---KATVTEKDVKDNYKpemKVSHILVK-----------DEKTAKEV 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 170 AEKIQkevekHPDKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLKEGKVSDVVKTDYGYHIIKADKEND- 248
Cdd:PRK02998 152 KEKVN-----NGEDFAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKEl 226

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 499622083 249 --FDKEKGKLKAQLIQTKIQK-DPKLLTDAYKELLDEYKVDYKDRDIKKAIE 297
Cdd:PRK02998 227 kpFDEVKDSIRKDLEQQRLQDtTGKWKQQVVNDLLKDADIKVNDKEFKDTFK 278
prsA PRK00059
peptidylprolyl isomerase; Provisional
 73-292 6.28e-14

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 71.28  E-value: 6.28e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  73 KDDVNTKDIDKEVEKEQKQ-YGGKDQFESMLKQQKMSIGDYKEQKKLQAYQKELLND---KVSMSDKEIKE--------- 139
Cdd:PRK00059 111 SEEELNKEVDKKINEIKKQfNNDEEQFEEALKATGFTEETFKEYLKNQIIIEKVINEvvkDVKVTDKDAQKyynenkskf 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 140 ----NTKKGSHILIKVKEnkddkeglsdkeakaKAEKIQKEVEKHPDkFGEIAKKESMDKASAKKDGSLGYV--VKGQME 213
Cdd:PRK00059 191 tekpNTMHLAHILVKTED---------------EAKKVKKRLDKGED-FAKVAKEVSQDPGSKDKGGDLGDVpySDSGYD 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 214 DKFEKALFKLKEGKVSDVVKTDYGYHIIKADKEN-----DFDKEKGKLKAQLIQtkiQKDPKLLTDAYKELLDEYKVDYK 288
Cdd:PRK00059 255 KEFMDGAKALKEGEISAPVKTQFGYHIIKAIKKKeypvkPFDSVKEDIKKQLLQ---EKQSEVFKKKIEEWKKALKVKKY 331


                 ....
gi 499622083 289 DRDI 292
Cdd:PRK00059 332 EKNL 335
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 146-253 4.94e-09

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 57.06  E-value: 4.94e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 146 HILIKVKENkddkegLSDKEAKAKAEKIQKEVEKHPDKFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKALFKLKE 225
Cdd:PRK10770 271 HILLKPSPI------MTDEQARAKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALMRLNK 344

                         90       100       110
                 ....*....|....*....|....*....|....
gi 499622083 226 GKVSDVVKTDYGYHII------KADKENDFDKEK 253
Cdd:PRK10770 345 GQISAPVHSSFGWHLIelldtrQVDKTDAAQKDR 378
prsA PRK01326
foldase protein PrsA; Reviewed
 13-290 5.94e-08

foldase protein PrsA; Reviewed


Pssm-ID: 179281 [Multi-domain]  Cd Length: 310  Bit Score: 53.28  E-value: 5.94e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  13 ASALLLGACGNSATDSKedtIISSKAGDVKVEDVMNKMGDEQIANTS-FSIMLNKLLADKYKDDVNTKDIDKEVEKEQKQ 91
Cdd:PRK01326  13 LSVATLAACSKTNENTK---VISMKGDTITVSDFYNQVKNNPSAQQAmLNLTISRVFEKQYGDKVSDKEVEKAYAKTAKQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  92 YGgkDQFESMLKQQKMSIGDYKEQ---KKLQAY------QKELLNDKVSmsdKEIKENTKKGSHILIKVKENKDDKEGLS 162
Cdd:PRK01326  90 YG--ASFSRALAQAGLTPETYKAQirtSKLVEYavkeaaKKELTDEAYK---KAYEEYTPEVTAQIIRLDNEDKAKSVLE 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 163 DKEAK-AKAEKIQKEVEKHPDKFGEIakkeSMDKASAkkdgslgyvvkgQMEDKFEKALFKLKEGKVSDVVKT------D 235
Cdd:PRK01326 165 EAKAEgADFAQIAKENTTTKEKKGEY----KFDSGST------------NVPEQVKKAAFALDEDGVSDVISVldptayQ 228

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 499622083 236 YGYHII----KADKENDFDKEKGKLKAQLIQTKiQKDPKLLTDAYKELLDEYKVDYKDR 290
Cdd:PRK01326 229 SKYYIVkvtkKTEKKSDWKDYKKRLKAIILAQK-QNDSNFQNKVIAKALDKANVKIKDK 286
PRK12450 PRK12450
foldase protein PrsA; Reviewed
 1-290 2.00e-07

foldase protein PrsA; Reviewed


Pssm-ID: 138982 [Multi-domain]  Cd Length: 309  Bit Score: 51.63  E-value: 2.00e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083   1 MKTFKKVLLPVT--ASALLLGACGNSATDSKedtIISSKAGDVKVEDVMNKMGDEQIANTS-FSIMLNKLLADKYKDDVN 77
Cdd:PRK12450   1 MKQMNKLITGVVtlATVVTLSACQSSHNNTK---LVSMKGDTITVSDFYNETKNTELAQKAmLSLVISRVFETQYANKVS 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  78 TKDIDKEVEKEQKQYGGkdQFESMLKQQKMSIGDYKEQ---KKLQAYQKELLNDKVSMSDKEIKENTKKGSHILIKvken 154
Cdd:PRK12450  78 DKEVEKAYKQTADQYGT--SFKTVLAQSGLTPETYKKQirlTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTA---- 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 155 kddKEGLSDKEAKAKAekIQKEVEKHPDKFGEIAKKESMdkASAKKDGSLGYVVKGQMEDKFEKALFKLKEGKVSDVVK- 233
Cdd:PRK12450 152 ---EIMQFEKEEDAKA--ALEAVKAEGADFAAIAKEKTI--AADKKTTYTFDSGETTLPAEVVRAASGLKEGNRSEIITa 224

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499622083 234 -----TDYGYHII----KADKENDFDKEKGKLKaQLIQTKIQKDPKLLTDAYKELLDEYKVDYKDR 290
Cdd:PRK12450 225 ldpatSKRTYHIIkvtkKATKKADWKAYQKRLK-DIIVTGKLKDPDFQNKVIAKALDKANVKIKDK 289
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 162-244 1.94e-06

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 49.24  E-value: 1.94e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 162 SDKEAKAKAEKIQKEVEkhpdkFGEIAKKESMDKASAKKDGSLGYVVKGQMEDKFEKAlfKLKE-GKVSDVVKTDYGYHI 240
Cdd:PRK10788 280 TEAEAKAVLDELKKGAD-----FATLAKEKSTDIISARNGGDLGWLEPATTPDELKNA--GLKEkGQLSGVIKSSVGFLI 352


                 ....
gi 499622083 241 IKAD 244
Cdd:PRK10788 353 VRLD 356
PRK15441 PRK15441
peptidyl-prolyl cis-trans isomerase C; Provisional
 164-242 9.08e-06

peptidyl-prolyl cis-trans isomerase C; Provisional


Pssm-ID: 185338 [Multi-domain]  Cd Length: 93  Bit Score: 43.47  E-value: 9.08e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499622083 164 KEAKAkAEKIQKEVEKHPDkFGEIAKKESMdKASAKKDGSLGYVVKGQMEDKFEKALFKLKEGKVSDVVKTDYGYHIIK 242
Cdd:PRK15441  13 KEEKL-ALDLLEQIKNGAD-FGKLAKKHSI-CPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIK 88
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 96-242 1.21e-03

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 40.49  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083  96 DQFESMLKQQKMSIGDYKEQKKLQAYQKELLNDKV------------SMSdKEIKENTKKG-----SHILIKVKENKDDK 158
Cdd:PRK10770  94 DQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVrrritilpqevdSLA-KQIGNQNDAStelnlSHILIPLPENPTQD 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499622083 159 EGlsdKEAKAKAEKIQKEVEKHPDkFGEIAKKESMDkASAKKDGSLGYVVKGQMEDKFEKALFKLKEGKVSDVVKTDYGY 238
Cdd:PRK10770 173 QV---DEAESQARSIVDQARNGAD-FGKLAIAYSAD-QQALKGGQMGWGRIQELPGLFAQALSTAKKGDIVGPIRSGVGF 247


                 ....
gi 499622083 239 HIIK 242
Cdd:PRK10770 248 HILK 251
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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