|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1004 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 764.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 1 MWhITKWALRSRLVTILLALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERFVwdewAD-K 79
Cdd:COG0841 1 MN-LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEAL----NGvE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 80 GLKHLTSTSSEGMSVIMAEFEYGTDMNAVGESLNEGISKI--SFPQAVTNfaammganaknPQIIPINMNIMPMVSLSLS 157
Cdd:COG0841 76 GIKYITSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRArsDLPEDVEP-----------PGVTKVNPSDFPVMVLALS 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 158 GD-LPPDQLKQIADSQIVPLLSQLDGVLRVDTEGGEKDYLVISPDPAKMTQYGITISQI------------AGILGTN-- 222
Cdd:COG0841 145 SDdLDELELSDYAERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVanairaqnvdvpAGRIGGGdr 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 223 ---------YSSLSDIEQISLGGDD---IKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIA 290
Cdd:COG0841 225 eytvrtngrLKTPEEFENIVIRTNDgsvVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLE 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 291 ELQGTLGDGVTISTVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLN 370
Cdd:COG0841 305 ELQASLPEGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLN 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 371 ILTLSAMTIAVGRLIDDSIVIIEVIYRRLRAGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFAL 450
Cdd:COG0841 385 ILTLFALVLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFAL 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 451 TVTFAMLASLIVALTLIPALSKWL----VSSKQKVVIAKDN----WYQKVYIKALKWTLGHRLAVVATAVLLLIGSAGLL 522
Cdd:COG0841 465 TVAIALLISLFVALTLTPALCARLlkphPKGKKGRFFRAFNrgfdRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLF 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 523 PMAGTSFMSgSFGEETISISISLPATADVSATSALTAKVEALLGANPSVRSYSSTIGTSAtsmagimsasqGGGGANTAS 602
Cdd:COG0841 545 GRLPTEFFP-EEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSG-----------GGSGSNSGT 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 603 IIVYLNSD-----------ADLQTELSNIT--------LASQGITTDGVIQVssgsgdsmggsissssinlSIQGQNREE 663
Cdd:COG0841 613 IFVTLKPWderdrsadeiiARLREKLAKIPgarvfvfqPPAGGLGSGAPIEV-------------------QLQGDDLEE 673
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 664 IASITAQLLEMLKGVDGLEELKSDLTTVVPVLNIAVDPAKVATSGLSPAQLA-QLQQEFvllmnGGALPGtTITLGSGSY 742
Cdd:COG0841 674 LAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAALGVTVADVAsTLRAAL-----GGRYVN-DFNRGGREY 747
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 743 PVYFKGIAGRLSDAEQAKNLKIGFP--VSVTLNDIAFVGVVAEPSHVSHTDTMLSATITGLITE-ANVGAVNAAVQEQVD 819
Cdd:COG0841 748 DVRVQAPEEDRNSPEDLENLYVRTPdgEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPgVSLGEALAAIEELAA 827
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 820 ALPSHPGVKVVTAGIAEQMGDTFIQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVVTGYTLGVSA 899
Cdd:COG0841 828 ELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYS 907
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 900 LMGMLMLVGIVLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALSVSSGTMLSAELAIVVI 979
Cdd:COG0841 908 QIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVI 987
|
1050 1060
....*....|....*....|....*
gi 499629239 980 GGMISSTFLTLFVIPAVYSMVYRGK 1004
Cdd:COG0841 988 GGLLFSTLLTLFVVPVLYVLLDRLR 1012
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
3-1004 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 574.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 3 HITKWALRSRLVTILLALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERfvwdewADKGLK 82
Cdd:COG3696 4 RIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIET------ALNGLP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 83 HLT---STSSEGMSVIMAEFEYGTDM----NAVGESLNEGISKIsfPQAVTnfaammganaknPQIIPIN--MNIMPMVS 153
Cdd:COG3696 78 GVKevrSISRFGLSVVTVIFEDGTDIywarQLVLERLQQVREQL--PAGVT------------PELGPIStgLGEIYQYT 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 154 L-SLSGDLPPDQLKQIADSQIVPLLSQLDGVLRVDTEGGE-KDYLVIsPDPAKMTQYGITISQIAGILGTN--------- 222
Cdd:COG3696 144 LeSDPGKYSLMELRTLQDWVIRPQLRSVPGVAEVNSFGGFvKQYQVL-VDPAKLRAYGLTLDDVIEALERNnanvgggyi 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 223 --------------YSSLSDIEQISLGGDD---IKLSDIATISLSPSP-SSAITRTNGKPSVGISVVKTESANTVETANA 284
Cdd:COG3696 223 erggqeylvrgiglIRSLEDIENIVVKTRNgtpVLLRDVAEVRIGPAPrRGAATLNGEGEVVGGIVLMLKGENALEVIEA 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 285 INEKIAELQGTLGDGVTISTVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSL 364
Cdd:COG3696 303 VKAKLAELKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRL 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 365 FGITLNILTLSAMTIAVGRLIDDSIVIIEVIYRRLR------AGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVG 438
Cdd:COG3696 383 FGISANLMSLGGLAIDFGIIVDGAVVMVENILRRLEenraagTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLE 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 439 GIVGEMFVPFALTVTFAMLASLIVALTLIPALSKWLVSSKQKvviAKDN----WYQKVYIKALKWTLGHRLAVVATAVLL 514
Cdd:COG3696 463 GVEGKLFRPMALTVIFALLGALLLSLTLVPVLASLLLRGKVP---EKENplvrWLKRLYRPLLRWALRHPKLVLAVALVL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 515 LIGSAGLLPMAGTSFMSgSFGEETISISISLPATADVSATSALTAKVEALLGANPSVRSYSSTIGTS--ATSMAGIMSA- 591
Cdd:COG3696 540 LVLALALFPRLGSEFLP-ELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAedATDPMGVNMSe 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 592 --------SQGGGGANTASIIvylnsdADLQTELSNI----TLASQ-----------GITTDGVIQVSsgsgdsmggsis 648
Cdd:COG3696 619 tfvilkprSEWRSGRTKEELI------AEMREALEQIpgvnFNFSQpiqmrvdellsGVRADVAVKIF------------ 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 649 sssinlsiqGQNREEIASITAQLLEMLKGVDGLEELKSDLTTVVPVLNIAVDPAKVATSGLSPAQLaqlqQEFVLLMNGG 728
Cdd:COG3696 681 ---------GDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADV----QDVVETAIGG 747
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 729 AlPGTTITLGSGSYPVYFKGIAGRLSDAEQAKNLKIGFP--VSVTLNDIAFVGVVAEPSHVSHTDTMLSATITGLITEAN 806
Cdd:COG3696 748 K-AVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPsgAQVPLSQVADIEVVEGPNQISRENGRRRIVVQANVRGRD 826
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 807 VGAVNAAVQEQVDA---LPshPGVKVVTAGIAEQMGDTFIQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIG 883
Cdd:COG3696 827 LGSFVAEAQAKVAEqvkLP--PGYYIEWGGQFENLQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIG 904
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 884 SMLALVVTGYTLGVSALMGMLMLVGIVLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALS 963
Cdd:COG3696 905 GVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALS 984
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*
gi 499629239 964 VSSGtmlsAE----LAIVVIGGMISSTFLTLFVIPAVYSMVYRGK 1004
Cdd:COG3696 985 TGPG----SEvqrpLATVVIGGLITSTLLTLLVLPALYLLFGRRR 1025
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
4-997 |
1.70e-162 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 504.91 E-value: 1.70e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 4 ITKWALRSRLVTILLALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERFVWdewADKGLKH 83
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMN---GLDGLKY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 84 LTSTSSEGMSVIMAEFEYGTDM----NAVGESLNEGISKIsfPQAVtnfaammganaKNPQIIPINMNIMPMVSLSLSGD 159
Cdd:pfam00873 78 MSSQSSYGLSSITLTFELGTDIdiarQDVQNRLQLATPLL--PEGV-----------QRPGISVIKTSLGPIMVLAVTSP 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 160 ---LPPDQLKQIADSQIVPLLSQLDGVLRVDTEGGEKDYLVISPDPAKMTQYGITIS-----------QIAG-------- 217
Cdd:pfam00873 145 dgsYTQTDLRDYADTNIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTdvvsalkeqnvNIGAgqlegqgl 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 218 ----ILGTNYSSLSDIEQISLGGDD---IKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIA 290
Cdd:pfam00873 225 qaliRAQGQLQSAEDFEKIIVKNQDgspVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLA 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 291 ELQGTLGDGVTISTVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLN 370
Cdd:pfam00873 305 ELKPTFPQGVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSIN 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 371 ILTLSAMTIAVGRLIDDSIVIIEVIYRRLRA-GESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFA 449
Cdd:pfam00873 385 TLTLGGLVLAIGLVVDDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFA 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 450 LTVTFAMLASLIVALTLIPALSKWLV----SSKQKVVIAKDN----WYQKVYIKALKWTLGHRLAVVATAVLLLIGSAGL 521
Cdd:pfam00873 465 ITIVLAILLSVLVALTLTPALCATLLkprrEPKHGGFFRWFNrmfdRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWL 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 522 LPMAGTSFMSgSFGEETISISISLPATADVSATSALTAKVEALLGANPSVRSYSSTIGTsatsmagimSASQGGGGANTA 601
Cdd:pfam00873 545 FVRIPTEFLP-EEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGF---------AFSGDNNGPNSG 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 602 SIIVYLNSDAD--------------LQTELSNITLASQGITtdGVIQVssgsGDSMGGSISSSSINLSIQGQNREEIASI 667
Cdd:pfam00873 615 DAFISLKPWKErpgpeksvqalierLRKALKQIPGANVFLF--QPIQL----RGLGTISGFRSDLQVKIFGDDLDALDEA 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 668 TAQLLEMLKGVDGLEELKSDLTTVVPVLNIAVDPAKVATSGLSPAQLAQLQQEFVllmnGGALPGTTITLGSgSYPVYFK 747
Cdd:pfam00873 689 RNQILAALAQLPGLSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTAL----GGSYVNDFPEGGR-VYDVVVQ 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 748 GIAGRLSDAEQAKNLKIGFP--VSVTLNDIAFVGVVAEPSHVSHTDTMLSATITGlitEANVGAVNAAVQEQVDALPSH- 824
Cdd:pfam00873 764 LPEDFRSSPEDIGQLYVRNPygKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISG---NVAAGDSLGDAMEAMAQIAKQv 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 825 ---PGVKVVTAGIAEQMGDTFIQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVVTGYTLGVSALM 901
Cdd:pfam00873 841 klpPGYGYTWTGQFEQEQLAGNSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQV 920
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 902 GMLMLVGIVLTNAIVLVSMVEQQRKH-GLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALSVSSGTMLSAELAIVVIG 980
Cdd:pfam00873 921 GLILLIGLAVKNAILMVEFANELREQeGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFG 1000
|
1050
....*....|....*..
gi 499629239 981 GMISSTFLTLFVIPAVY 997
Cdd:pfam00873 1001 GLVTSTVLTLLVVPVFY 1017
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1002 |
6.18e-147 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 463.33 E-value: 6.18e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 5 TKWALRSRLVTILLALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERFVWdewADKGLKHL 84
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLA---QIEGIDEM 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 85 TSTSSEGMSVIMAEFEYGTDMNAvgeslneGISKIsfpQAVTNFA-AMMGANAKNPQII-PINMNIMPMVSLSLSGD-LP 161
Cdd:NF033617 78 TSQSSLGYSTITLQFRLGTDLDV-------ALSEV---QAAINAAqSLLPSEAPDPPVYrKANSADTPIMYIGLTSEeMP 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 162 PDQLKQIADSQIVPLLSQLDGVLRVDTEGGEKDYLVISPDPAKMTQYGITISQIAGILGTN------------------- 222
Cdd:NF033617 148 RGQLTDYAERVLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNnvnspkgavrgdsvvstvr 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 223 ----YSSLSDIEQI----SLGGDDIKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIAELQG 294
Cdd:NF033617 228 andqLKTAEDYEDLvikyADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQE 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 295 TLGDGVTISTVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTL 374
Cdd:NF033617 308 TLPKNIKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 375 SAMTIAVGRLIDDSIVIIEVIYRRLRAGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFALTVTF 454
Cdd:NF033617 388 MALVLAIGLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAG 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 455 AMLASLIVALTLIPALSKWLVSSKQKvviaKDNWYQKV----------YIKALKWTLGHRLAVVATAVLLLIGSAGLLPM 524
Cdd:NF033617 468 AVIISGIVALTLTPMMCSRLLKANEK----PGRFARAVdrffdgltarYGRGLKWVLKHRPLTLVVALATLALLPLLYVF 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 525 AGTSFmsgsFGEE---TISISISLPATADVSATSALTAKVEALLGANPSVRSYSSTIGTSatsmagimsasqGGGGANTA 601
Cdd:NF033617 544 IPKEL----APSEdrgVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVG------------GNPGDNTG 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 602 SIIVYLNSDADLQTELSNITLASQGITTD--GV-IQVSSGSGDSMGGSISSSSINLSIQGQNREEIASITAQLLEMLKGV 678
Cdd:NF033617 608 FGIINLKPWDERDVSAQEIIDRLRPKLAKvpGMdLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKS 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 679 DGLEELKSDLTTVVPVLNIAVDPAKVATSGLSPAQLAQLQQEFvllMNGGALpgTTITLGSGSYPVYFKGIAGRLSDAEQ 758
Cdd:NF033617 688 PQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVA---FGQRQV--NTIYTDGNQYKVVLEVDRRYRLNPEA 762
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 759 AKN--LKIGFPVSVTLNDIAFVGVVAEPSHVSHTDTMLSATITG-LITEANVG-AVNAAVQEQVDALPShpGVKVVTAGI 834
Cdd:NF033617 763 LNQiyVRSNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFnLAPGVSLGeAIEALDQAAKELLPS--GISGSFQGA 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 835 AEQMGDTFIQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVVTGYTLGVSALMGMLMLVGIVLTNA 914
Cdd:NF033617 841 ARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNG 920
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 915 IVLVSMV-EQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALSVSSGTMLSAELAIVVIGGMISSTFLTLFVI 993
Cdd:NF033617 921 ILMVEFAnELQRHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVL 1000
|
....*....
gi 499629239 994 PAVYSMVYR 1002
Cdd:NF033617 1001 PVVYLLLAR 1009
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
4-1002 |
9.50e-111 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 367.93 E-value: 9.50e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 4 ITKWALRSRLVTILLALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERFVWdewADKGLKH 83
Cdd:TIGR00914 5 IISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMA---GLPGLET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 84 LTSTSSEGMSVIMAEFEYGTDMNAVGESLNEGISKISfPQAVTNFAAMMGANAKN-PQIIPINMNIMPMVSLSLSGDLPP 162
Cdd:TIGR00914 82 TRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQAR-DNLPEGVSPEMGPISTGlGEIFLYTVEAEEGARKKDGGAYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 163 DQLKQIADSQIVPLLSQLDGVLRVDTEGGEKDYLVISPDPAKMTQYGITISQIAGIL-------GTNY------------ 223
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALernnqnvGAGYierrgeqylvra 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 224 ----SSLSDIEQISLG---GDDIKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIAELQGTL 296
Cdd:TIGR00914 241 pgqvQSMDDIRNIVIAtgeGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 297 GDGVTISTVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSA 376
Cdd:TIGR00914 321 PEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 377 mtIAVGRLIDDSIVIIEVIYRRL-----RAG------ESFKEaAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMF 445
Cdd:TIGR00914 401 --LDFGLIVDGAVVIVENAHRRLaeaqhHHGrqltlkERLHE-VFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMF 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 446 VPFALTVTFAMLASLIVALTLIPALSKWLVSSKqkvVIAKDNWY----QKVYIKALKWTLGHRLAVVATAVLLLIGSAGL 521
Cdd:TIGR00914 478 HPMAFTVVLALAGAMILSLTFVPAAVALFIRGK---VAEKENRLmrvlKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWI 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 522 LPMAGTSFMSgSFGEETISI-SISLPATAdVSATSALTAKVEALLGANPSVRSYSSTIGTSAT---SMAGIMS------- 590
Cdd:TIGR00914 555 ASRVGGEFIP-SLNEGDLAYqALRIPGTS-LAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIatdPMPPNASdtyiilk 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 591 -ASQGGGGANTASIIVYLNSDADLQTELSN----------ITLASQGITTDGVIQVSsgsgdsmggsissssinlsiqGQ 659
Cdd:TIGR00914 633 pESQWPEGKKTKEDLIEEIQEATVRIPGNNyeftqpiqmrFNELISGVRSDVAVKVF---------------------GD 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 660 NREEIASITAQLLEMLKGVDGLEELKSDLTTVVPVLNIAVDPAKVATSGLSPAQLaqlqQEFVLLMNGGALPGTTITlGS 739
Cdd:TIGR00914 692 DLDDLDATAEKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDV----QDTVATAVGGRMSGETFE-GD 766
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 740 GSYPVYFKGIAGRLSDAEQAKNLKIGFPVS-------VTLNDIAFVGVVAEPSHVSHTD----TMLSATITGLITEANVG 808
Cdd:TIGR00914 767 RRFDIVIRLPESLRESPQALRQLPIPLPLSedarkqfIPLSDVADLRVSPGPNQISRENgkrrVVVSANVRGRDLGSFVD 846
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 809 AVNAAVQEQVDaLPshPGVKVVTAGIAEQMGDTFIQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLAL 888
Cdd:TIGR00914 847 DAKKAIAEQVK-LP--PGYWITWGGQFEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFAL 923
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 889 VVTGYTLGVSALMGMLMLVGIVLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALSVSSGT 968
Cdd:TIGR00914 924 WLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGA 1003
|
1050 1060 1070
....*....|....*....|....*....|....
gi 499629239 969 MLSAELAIVVIGGMISSTFLTLFVIPAVYSMVYR 1002
Cdd:TIGR00914 1004 EVQRPLATVVIGGIITATLLTLFVLPALYRLVHR 1037
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
18-1002 |
7.19e-84 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 293.17 E-value: 7.19e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 18 LALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERfvwDEWADKGLKHLTSTS-SEGMSVIM 96
Cdd:TIGR00915 15 IAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQ---NMNGIDGLRYMSSSSdSDGSMTIT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 97 AEFEYGTDMN----AVGESLNEGISKIsfPQAVTNFAAMMGANAKNpqiipinmNIMPMVSLSLSGDLPPDQLKQIADSQ 172
Cdd:TIGR00915 92 LTFEQGTDPDiaqvQVQNKLQLATPLL--PQEVQRQGVRVEKASSN--------FLMVIGLVSDDGSMTKEDLSDYAASN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 173 IVPLLSQLDGVLRVDTEGGEKDyLVISPDPAKMTQYGIT----ISQI--------AGILG-----------------TNY 223
Cdd:TIGR00915 162 MVDPLSRLEGVGDVQLFGSQYA-MRIWLDPAKLNSYQLTpadvISAIsaqnaqisAGQLGglpavpgqqlnatiiaqTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 224 SSLSDIEQISL----GGDDIKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIAELQGTLGDG 299
Cdd:TIGR00915 241 QTPEQFENILLkvntDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 300 VTISTVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTI 379
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 380 AVGRLIDDSIVIIEVIYRRLRA-GESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFALTVTFAMLA 458
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEeGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 459 SLIVALTLIPALSKWLVSSKQKVVIAKD-----NWYQKV-------YIKALKWTLGHRLAVVATAVLLLIGSAGLLPMAG 526
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPIEKGEHHEKkggffGWFNRMfdssthgYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 527 TSFMSgsfgEE---TISISISLPATADVSATSALTAKVEALLGANPSvRSYSSTIGTSATSMAgimsasqgGGGANTASI 603
Cdd:TIGR00915 561 TSFLP----DEdqgVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEK-ANVESVFTVNGFSFA--------GRGQNMGMA 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 604 IVYLN-------SDADLQTELSNITLASQGITTDGVIQVSSGSGDSMGGSISSSSINLSIQGQNREEIASITAQLLEMLK 676
Cdd:TIGR00915 628 FIRLKdweertgKENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAA 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 677 GVDGLEELKSDLTTVVPVLNIAVDPAKVATSGLSPAQLaqlqqefvllmnggalpGTTITLGSGS------------YPV 744
Cdd:TIGR00915 708 QNPALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADI-----------------NTTLSTAWGSsyvndfidrgrvKRV 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 745 YFKGIAGRLSDAEQAKNLKI--GFPVSVTLNDIAFVGVVAEPSHVSHTDTMLSATITGlitEAN----VGAVNAAVQEQV 818
Cdd:TIGR00915 771 YVQAEEDARMSPEDINKWYVrnASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILG---SAApgvsTGQAMAAMEAIA 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 819 DALPshPGVKVVTAGIAEQMGDTFIQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVVTGYTLGVS 898
Cdd:TIGR00915 848 QKLP--PGFGFSWTGMSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVY 925
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 899 ALMGMLMLVGIVLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALSVSSGTMLSAELAIVV 978
Cdd:TIGR00915 926 FQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGV 1005
|
1050 1060
....*....|....*....|....
gi 499629239 979 IGGMISSTFLTLFVIPAVYSMVYR 1002
Cdd:TIGR00915 1006 FGGMVTATVLAIFFVPLFYVVVRR 1029
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
15-997 |
4.32e-77 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 273.53 E-value: 4.32e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 15 TILLALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERFVWdewADKGLKHLTSTSSEGMSV 94
Cdd:PRK10614 14 TILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLG---RIAGVNEMTSSSSLGSTR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 95 IMAEFEYGTDMNAVGESLnegiskisfpQAVTNFAAMM--GANAKNPQIIPINMNIMPMVSLSLSGDL-PPDQLKQIADS 171
Cdd:PRK10614 91 IILQFDFDRDINGAARDV----------QAAINAAQSLlpSGMPSRPTYRKANPSDAPIMILTLTSDTySQGQLYDFAST 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 172 QIVPLLSQLDGVLRVDTEGGEKDYLVISPDPAKMTQYGITI---------------------SQIAGILGTNYSSLSDIE 230
Cdd:PRK10614 161 QLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLddvrqaisnanvrrpqgavedGTHRWQIQTNDELKTAAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 231 QISL-----GGDDIKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIAELQGTLGDGVTISTV 305
Cdd:PRK10614 241 YQPLiihynNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 306 FDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLI 385
Cdd:PRK10614 321 QDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 386 DDSIVIIEVIYRRLRAGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFALTVTFAMLASLIVALT 465
Cdd:PRK10614 401 DDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 466 LIPALSKWLVSSKQ-----------KVVIAkdnwYQKVYIKALKWTLGHRLAVvataVLLLIGSAGLlpmagtsfmsgsf 534
Cdd:PRK10614 481 LTPMMCAWLLKSSKpreqkrlrgfgRMLVA----LQQGYGRSLKWVLNHTRWV----GVVLLGTIAL------------- 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 535 geeTISISISLPAT---------------ADVSAT-SALTAKVE---ALLGANPSVRSYSSTIGTSATSMaGIMSAS--- 592
Cdd:PRK10614 540 ---NVWLYISIPKTffpeqdtgrlmgfiqADQSISfQAMRGKLQdfmKIIRDDPAVDNVTGFTGGSRVNS-GMMFITlkp 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 593 QGGGGANTASIIVYLNSDADLQTELSNITLASQGITTDGviqvssgsgdsmggsissssinlsiqgqnREEIASITAQLL 672
Cdd:PRK10614 616 LSERSETAQQVIDRLRVKLAKEPGANLFLMAVQDIRVGG-----------------------------RQSNASYQYTLL 666
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 673 ---------------EMLKGVDGLEELKSDLTTVVPVLNIAVDPAKVATSGLSpaqlaqLQQEFVLLMNG-GALPGTTIT 736
Cdd:PRK10614 667 sddlaalrewepkirKALAALPELADVNSDQQDKGAEMALTYDRDTMARLGID------VQAANSLLNNAfGQRQISTIY 740
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 737 LGSGSYPVYFkGIAGRLSDAEQAknLKIGFPV-----SVTLNDIAFVGVVAEPSHVSHTDTMLSATIT-GLITEANVGAV 810
Cdd:PRK10614 741 QPLNQYKVVM-EVDPRYTQDISA--LEKMFVInnegkAIPLSYFAKWQPANAPLSVNHQGLSAASTISfNLPTGKSLSDA 817
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 811 NAAVQEQVDALPSHPGVKVVTAGIAEQMGDTFIQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVV 890
Cdd:PRK10614 818 SAAIERAMTQLGVPSTVRGSFAGTAQVFQETMNSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALEL 897
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 891 TGYTLGVSALMGMLMLVGIVLTNAIVLVSM-VEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALSVSSGTM 969
Cdd:PRK10614 898 FNAPFSLIALIGIMLLIGIVKKNAIMMVDFaLEAQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAE 977
|
1050 1060
....*....|....*....|....*...
gi 499629239 970 LSAELAIVVIGGMISSTFLTLFVIPAVY 997
Cdd:PRK10614 978 LRQPLGITIVGGLVMSQLLTLYTTPVVY 1005
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
15-997 |
1.06e-72 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 261.20 E-value: 1.06e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 15 TILLALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERFVWDEwadKGLKHLTSTSSEGMSV 94
Cdd:PRK10503 23 TTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQM---SGLKQMSSQSSGGASV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 95 IMAEFEYGTDMNAVGESLNEGISkisfpqAVTNfaaMMGANAKNPQIIP-INMNIMPMVSLSLSGD-LPPDQLKQIADSQ 172
Cdd:PRK10503 100 ITLQFQLTLPLDVAEQEVQAAIN------AATN---LLPSDLPNPPVYSkVNPADPPIMTLAVTSTaMPMTQVEDMVETR 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 173 IVPLLSQLDGVLRVDTEGGEKDYLVISPDPAKMTQYGITISQI-AGILGTNYSS-------------LSDIEQISL---- 234
Cdd:PRK10503 171 VAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVrTAITGANVNSakgsldgptravtLSANDQMQSaeey 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 235 --------GGDDIKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIAELQGTLGDGVTISTVF 306
Cdd:PRK10503 251 rqliiayqNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLS 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 307 DQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLID 386
Cdd:PRK10503 331 DRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVD 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 387 DSIVIIEVIYRRLRAGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFALTVTFAMLASLIVALTL 466
Cdd:PRK10503 411 DAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTL 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 467 IPALSKWLVSS----KQ-KVVIAKDNWYQKV---YIKALK------W-TLGHRLAVVATAVLL-LIGSAGLLPMAGTSFM 530
Cdd:PRK10503 491 TPMMCARMLSQeslrKQnRFSRASERMFDRViaaYGRGLAkvlnhpWlTLSVALSTLLLTVLLwIFIPKGFFPVQDNGII 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 531 SGsfgeetisiSISLPATADVSATSALTAKVEALLGANPSVRSYSSTIGTSATSMAgimsasqggggANTASIIVYLNSD 610
Cdd:PRK10503 571 QG---------TLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPS-----------LNSARLQINLKPL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 611 AD-----------LQTELSNITLAS------QGITTDgviqvssgsgdsmgGSISSSSINLSIQGQNREEIASITAQLLE 673
Cdd:PRK10503 631 DErddrvqkviarLQTAVAKVPGVDlylqptQDLTID--------------TQVSRTQYQFTLQATSLDALSTWVPKLME 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 674 MLKGVDGLEELKSDLTTVVPVLNIAVDPAKVATSGLSPAQL-AQLQQEFvllmngGALPGTTITLGSGSYPVYFKGIAGR 752
Cdd:PRK10503 697 KLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVdNALYNAF------GQRLISTIYTQANQYRVVLEHNTEN 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 753 LS--DAEQAKNLKIGFPVSVTLNDIAFVGVVAEPSHVSHTDTMLSATIT-----GLITEANVGAVNAAvqEQVDALPSHP 825
Cdd:PRK10503 771 TPglAALDTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISfnvpdGYSLGDAVQAIMDT--EKTLNLPADI 848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 826 GVKVVTAGIAEQ--MGDTfIQMGIAILVAIAIVFLIvilMMRSIRNPLLIMLSIPLAFIGSMLALVVTGYTLGVSALMGM 903
Cdd:PRK10503 849 TTQFQGSTLAFQsaLGST-VWLIVAAVVAMYIVLGV---LYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGI 924
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 904 LMLVGIVLTNAIVLVSM-VEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALSVSSGTMLSAELAIVVIGGM 982
Cdd:PRK10503 925 ILLIGIVKKNAIMMIDFaLAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGL 1004
|
1050
....*....|....*
gi 499629239 983 ISSTFLTLFVIPAVY 997
Cdd:PRK10503 1005 IVSQVLTLFTTPVIY 1019
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
29-1002 |
1.88e-67 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 245.51 E-value: 1.88e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 29 AFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERFVWdewADKGLKHLTSTSSEGMSVIMAEFEYGTDMNAV 108
Cdd:PRK09579 28 AWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLA---SAEGIDYMTSVSRQNFSIISIYARIGADSDRL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 109 GESL----NEGISKIsfPQavtnfaammgaNAKNPQIIPINMNIMPMVSLSL-SGDLPPDQLKQIADSQIVPLLSQLDGV 183
Cdd:PRK09579 105 FTELlakaNEVKNQL--PQ-----------DAEDPVLSKEAADASALMYISFySEEMSNPQITDYLSRVIQPKLATLPGM 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 184 LRVDTEGGEKDYLVISPDPAKMTQYGITISQI------------AGILGTNY--------------SSLSDIEQISLGGD 237
Cdd:PRK09579 172 AEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVtqavrrynflsaAGEVKGEYvvtsinastelksaEAFAAIPVKTSGDS 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 238 DIKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIAELQGTLGDGVTISTVFDQSDFIGTSIS 317
Cdd:PRK09579 252 RVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIAYDATLFIQASID 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 318 QLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVIIEVIYR 397
Cdd:PRK09579 332 EVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHR 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 398 RLRAGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFALTVTFAMLASLIVALTLIPALSKWLVSS 477
Cdd:PRK09579 412 HIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALTLSPMMCALLLRH 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 478 KQK---VVIAKDNWYQKV---YIKALKWTLGHRLAVVATAVLLLigsaGLLP---MAGTSFMSGSFGEETISISISLPAT 548
Cdd:PRK09579 492 EENpsgLAHRLDRLFERLkqrYQRALHGTLNTRPVVLVFAVIVL----ALIPvllKFTQSELAPEEDQGIIFMMSSSPQP 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 549 ADVSATSALTAKVEALLGANPSVrsYSStigtsaTSMAGIMSASQGGGGAntasIIVYLNSDADLQTELsnITLASQGIT 628
Cdd:PRK09579 568 ANLDYLNAYTDEFTPIFKSFPEY--YSS------FQINGFNGVQSGIGGF----LLKPWNERERTQMEL--LPLVQAKLE 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 629 TDGVIQVSSGSGDSMGGSISSSSINLSIQGQNR-EEIASITAQLLEMLKGVDGLEELKSDLTTVVPVLNIAVDPAKVATS 707
Cdd:PRK09579 634 EIPGLQIFGFNLPSLPGTGEGLPFQFVINTANDyESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDIDRAKAAQM 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 708 GLSpaqLAQLQQEFVLLMNGGALpgTTITLGSGSYPVY------FKGIAGRLSD--AEQAKNLKIGFPVSVTLNDiafvg 779
Cdd:PRK09579 714 GVS---MQDLGGTLATLLGEGEI--NRFTIDGRSYKVIaqverpYRDNPGWLNNyyVKNEQGQLLPLSTLITLSD----- 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 780 vVAEPSHVSHTDTMLSATITGLITEANVGAVNAAVQEQVDALPshPGVKVVTAGIAEQmgdtFIQMGIAILV----AIAI 855
Cdd:PRK09579 784 -RARPRQLNQFQQLNSAIISGFPIVSMGEAIETVQQIAREEAP--EGFAFDYAGASRQ----YVQEGSALWVtfglALAI 856
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 856 VFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVVTGYTLGVSALMGMLMLVGIVLTNAIVLVSMVEQQRK-HGLSVKDA 934
Cdd:PRK09579 857 IFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHeQGLSRREA 936
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499629239 935 LIEGGKIRLRPIVMTALTTILAMIPMALSVSSGTMLSAELAIVVIGGMISSTFLTLFVIPAVYSMVYR 1002
Cdd:PRK09579 937 IEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAK 1004
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
17-1002 |
1.13e-60 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 225.09 E-value: 1.13e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 17 LLALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERFVwdewadKGLKHLTSTSSE----GM 92
Cdd:PRK10555 14 VLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNM------TGLDNLMYMSSQssgtGQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 93 SVIMAEFEYGTD----MNAVGESLNEGISKIsfPQAVTNFAAMMGANAKNpqiipinmNIMPMVSLSLSGDLPPDQLKQI 168
Cdd:PRK10555 88 ASVTLSFKAGTDpdeaVQQVQNQLQSAMRKL--PQAVQNQGVTVRKTGDT--------NILTIAFVSTDGSMDKQDIADY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 169 ADSQIVPLLSQLDGVLRVDTEGGEKDyLVISPDPAKMTQYGITI-----------SQIA-GILG--------------TN 222
Cdd:PRK10555 158 VASNIQDPLSRVNGVGDIDAYGSQYS-MRIWLDPAKLNSFQMTTkdvtdaiesqnAQIAvGQLGgtpsvdkqalnatiNA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 223 YSSLSDIEQ---ISL----GGDDIKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIAELQGT 295
Cdd:PRK10555 237 QSLLQTPEQfrdITLrvnqDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 296 LGDGVTISTVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLS 375
Cdd:PRK10555 317 FPHGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMF 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 376 AMTIAVGRLIDDSIVIIEVIYRRL-RAGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFALTVTF 454
Cdd:PRK10555 397 AMVLAIGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVS 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 455 AMLASLIVALTLIPALSK-------------------WLVSSKQKVVIAKDNWYQKVYIKALKWTLGHRLAVVATAVLLL 515
Cdd:PRK10555 477 AMVLSVLVAMILTPALCAtllkplkkgehhgqkgffgWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFL 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 516 IGSAGLLPMAGtsfmSGSFgeetiSISISLPATADVSATSALTAKVEA--LLGANPSVRSYSSTIGtsatsmagimsASQ 593
Cdd:PRK10555 557 RLPTSFLPLED----RGMF-----TTSVQLPSGSTQQQTLKVVEKVEKyyFTHEKDNVMSVFATVG-----------SGP 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 594 GGGGANTASIIVYLNS----DADLQTELSNITLASQGITTDGVIQVSSGSGDSMGGSISSSSINLSIQ---GQNREEIAS 666
Cdd:PRK10555 617 GGNGQNVARMFIRLKDwderDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQdhaGAGHDALMA 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 667 ITAQLLEMLKGVDGLEELKSDLTTVVPVLNIAVDPAKVATSGLSPAQL-AQLQ----QEFVL-LMNGGALPGTTITlGSG 740
Cdd:PRK10555 697 ARNQLLALAAKNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDInDTLQtawgSSYVNdFMDRGRVKKVYVQ-AAA 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 741 SYPV--------YFKGIAGRLS--DAEQAKNLKIGFPVSVTLNDIAFVGVVAEPShvshtdtmlsatiTGLITeanvGAV 810
Cdd:PRK10555 776 PYRMlpddinlwYVRNKDGGMVpfSAFATSRWETGSPRLERYNGYSAVEIVGEAA-------------PGVST----GTA 838
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 811 NAAVQEQVDALPSHPGVKVVTAGIAEQMGDTfiQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVV 890
Cdd:PRK10555 839 MDIMESLVKQLPNGFGLEWTAMSYQERLSGA--QAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWM 916
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 891 TGYTLGVSALMGMLMLVGIVLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALSVSSGTML 970
Cdd:PRK10555 917 RGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGS 996
|
1050 1060 1070
....*....|....*....|....*....|..
gi 499629239 971 SAELAIVVIGGMISSTFLTLFVIPAVYSMVYR 1002
Cdd:PRK10555 997 QHAVGTGVMGGMISATILAIFFVPLFFVLVRR 1028
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
17-1002 |
1.39e-60 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 225.12 E-value: 1.39e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 17 LLALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERfvwDEWADKGLKHLTSTSSEGMSVIM 96
Cdd:PRK09577 14 VISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIER---EMNGAPGLLYTSATSSAGQASLS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 97 AEFEYGT--DMNAVGESLNEGISKISFPQAVTNFAAMMGANAKNPQIIpinmnimpmVSL-SLSGDLPPDQLKQIADSQI 173
Cdd:PRK09577 91 LTFKQGVnaDLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLI---------VSLtSDDGRLTGVELGEYASANV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 174 VPLLSQLDGVLRVDTEGGEKDyLVISPDPAKMTQYGITISQIA------------GILGTN-----------------YS 224
Cdd:PRK09577 162 LQALRRVEGVGKVQFWGAEYA-MRIWPDPVKLAALGLTASDIAsavrahnarvtiGDIGRSavpdsapiaatvfadapLK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 225 SLSDIEQISL----GGDDIKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIAELQGTLGDGV 300
Cdd:PRK09577 241 TPEDFGAIALraraDGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPGV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 301 TISTVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIA 380
Cdd:PRK09577 321 KYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 381 VGRLIDDSIVIIEVIyRRLRAGESFK--EAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFALTVTFAMLA 458
Cdd:PRK09577 401 IGILVDDAIVVVENV-ERLMVEEGLSpyDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 459 SLIVALTLIPALSKWLVSSK--------------QKVVIAKDNWYQ----KVYIKALKWTLGHRLAVVATAVLLLIGSAG 520
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPVdgdhhekrgffgwfNRFVARSTQRYAtrvgAILKRPLRWLVVYGALTAAAALLFTRLPTA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 521 LLPMAGT-SFMsgsfgeetisISISLPATADVSATSALTAKVEALLGANPSVrSYSSTIGtsatsmagimSASQGGGGAN 599
Cdd:PRK09577 560 FLPDEDQgNFM----------VMVIRPQGTPLAETMQSVREVESYLRRHEPV-AYTFALG----------GFNLYGEGPN 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 600 TASIIVYL-------NSDADLQTELSNITLASQGITTDGVIQVSSGSGDSMGGSISSSSINLSIQGQNREEIASITAQLL 672
Cdd:PRK09577 619 GGMIFVTLkdwkerkAARDHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLL 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 673 EMLKGVDGLEELKSDLTTVVPVLNIAVDPAKVATSGLSPAQLaqlqQEFVLLMNGGALPGTTITlGSGSYPVYFKGIAGR 752
Cdd:PRK09577 699 AEGAKDPALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEI----NTTLAVMFGSDYIGDFMH-GSQVRRVIVQADGRH 773
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 753 LSDAEQAKNLKIGFPVS--VTLNDIAFVGVVAEPSHVSHTDTMLSATITGLITEA-NVGAVNAAVQEQVDALPSHPGVKV 829
Cdd:PRK09577 774 RLDPDDVKKLRVRNAQGemVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGhSSGEAMAAIERIAATLPAGIGYAW 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 830 VTAGIAEQMGDTFIQMGIAilVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVVTGYTLGVSALMGMLMLVGI 909
Cdd:PRK09577 854 SGQSFEERLSGAQAPMLFA--LSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGL 931
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 910 VLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALsvSSGTMLSAELAI--VVIGGMISSTF 987
Cdd:PRK09577 932 SAKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAF--ASGAASGAQIAIgtGVLGGVITATV 1009
|
1050
....*....|....*
gi 499629239 988 LTLFVIPAVYSMVYR 1002
Cdd:PRK09577 1010 LAVFLVPLFFVVVGR 1024
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
17-1002 |
3.72e-53 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 202.06 E-value: 3.72e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 17 LLALAVAGASLWAFMGIKVELMPDISLPYTTVVTVYPQATPDAVVRDVTTPIERfvwDEWADKGLKHLTSTS-SEGMSVI 95
Cdd:PRK15127 14 VIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQ---NMNGIDNLMYMSSNSdSTGTVQI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 96 MAEFEYGTDMNAVGESLNEGISKIS--FPQAVTNFAAMMGANAKNpqiipinmNIMPMVSLSLSGDLPPDQLKQIADSQI 173
Cdd:PRK15127 91 TLTFESGTDADIAQVQVQNKLQLAMplLPQEVQQQGVSVEKSSSS--------FLMVVGVINTDGTMTQEDISDYVAANM 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 174 VPLLSQLDGVLRVDTEGGEKDyLVISPDPAKMTQYGIT----ISQI--------AGILG-----------------TNYS 224
Cdd:PRK15127 163 KDPISRTSGVGDVQLFGSQYA-MRIWMNPNELNKFQLTpvdvINAIkaqnaqvaAGQLGgtppvkgqqlnasiiaqTRLT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 225 SLSDIEQISL----GGDDIKLSDIATISLSPSPSSAITRTNGKPSVGISVVKTESANTVETANAINEKIAELQGTLGDGV 300
Cdd:PRK15127 242 STEEFGKILLkvnqDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 301 TISTVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIA 380
Cdd:PRK15127 322 KIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 381 VGRLIDDSIVIIEVIYRRL-RAGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFALTVTFAMLAS 459
Cdd:PRK15127 402 IGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALS 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 460 LIVALTLIPALSKWLVSSKQKVVIAKDN-----WYQKVYIKALKW---TLGHRLAVVATAVLL----LIGSAGLLPMAGT 527
Cdd:PRK15127 482 VLVALILTPALCATMLKPIAKGDHGEGKkgffgWFNRMFEKSTHHytdSVGNILRSTGRYLVLyliiVVGMAYLFVRLPS 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 528 SFMSgsfgEETISISIS---LPAtadvSATSALTAKVeallgANPSVRSYSSTIGTSATSMAGIMSASQGGGGANTASII 604
Cdd:PRK15127 562 SFLP----DEDQGVFLTmvqLPA----GATQERTQKV-----LNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAF 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 605 VYLNSDADLQTELSNI-TLASQGITT-----DGVIQVSSGSGDSMGGSISSSSINLSIQG--------QNREEIASITAQ 670
Cdd:PRK15127 629 VSLKDWADRPGEENKVeAITMRATRAfsqikDAMVFAFNLPAIVELGTATGFDFELIDQAglghekltQARNQLLGEAAK 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 671 LLEMLKGV--DGLEElksdlttvVPVLNIAVDPAKVATSGLSpaqlaqlqqefvllmnggaLPGTTITLGS---GSYPVY 745
Cdd:PRK15127 709 HPDMLVGVrpNGLED--------TPQFKIDIDQEKAQALGVS-------------------ISDINTTLGAawgGSYVND 761
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 746 F--KGIAGRLSDAEQAKNLKIGFPVS---VTLNDIAFVGVVAEPS--------HVSHTDTMLSATITGLITEA-NVGAVN 811
Cdd:PRK15127 762 FidRGRVKKVYVMSEAKYRMLPDDIGdwyVRAADGQMVPFSAFSSsrweygspRLERYNGLPSMEILGQAAPGkSTGEAM 841
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 812 AAVQEQVDALPShpGVKVVTAGIAEQMGDTFIQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVVT 891
Cdd:PRK15127 842 ELMEELASKLPT--GVGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFR 919
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 892 GYTLGVSALMGMLMLVGIVLTNAIVLVSMVEQ-QRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALSVSSGTML 970
Cdd:PRK15127 920 GLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDlMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGA 999
|
1050 1060 1070
....*....|....*....|....*....|..
gi 499629239 971 SAELAIVVIGGMISSTFLTLFVIPAVYSMVYR 1002
Cdd:PRK15127 1000 QNAVGTGVMGGMVTATVLAIFFVPVFFVVVRR 1031
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
273-1002 |
1.40e-25 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 113.80 E-value: 1.40e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 273 TESANTVETANAINEKIAELQGTLGDGVTISTVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIP 352
Cdd:COG1033 174 SSDLDRKEVVAEIRAIIAKYEDPGVEVYLTGFPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVL 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 353 LSIFFGFLCMSLFGITLNILT--LSAMTIAVGrlIDDSIVIIEVIYRRLRAGESFKEAAIGGAKEVATPITTATLATVAI 430
Cdd:COG1033 254 LAVIWTLGLMGLLGIPLSPLTilVPPLLLAIG--IDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIG 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 431 FAPLMFVGgivGEMFVPFALTVTFAMLASLIVALTLIPALSKWLVSSKQKVVIAKDNWYQKVYIKAL-KWTLGHRLAVVA 509
Cdd:COG1033 332 FLSLLFSD---IPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLLAKLaRFVLRRPKVILV 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 510 TAVLLLIGSAGLLPMAGTSF-MSGSFGEETisisislPATADvsatsalTAKVEALLganpsvrsysstigtsatsmagi 588
Cdd:COG1033 409 VALVLAVVSLYGISRLKVEYdFEDYLPEDS-------PIRQD-------LDFIEENF----------------------- 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 589 msasqggGGANTASIIVYlnsdadlqtelsniTLASQGITTDGVIQVSsgsgdsmggsissssinlsiqgqnreeiasit 668
Cdd:COG1033 452 -------GGSDPLEVVVD--------------TGEPDGLKDPEVLKEI-------------------------------- 478
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 669 AQLLEMLKGVDGLEELKSdLTTVVPVLNIAVDPAKVATSGLSPAQLAQLQQEFVLLMNGGALPGTTITlgsgsypvyfkg 748
Cdd:COG1033 479 DRLQDYLESLPEVGKVLS-LADLVKELNQALNEGDPKYYALPESRELLAQLLLLLSSPPGDDLSRFVD------------ 545
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 749 iagrlSDAEQAknlkigfPVSVTLNDIAfvgvvaepshvshtdtmlSATITGLITEANVGAVNAAVQEQVDALPShpGVK 828
Cdd:COG1033 546 -----EDYSAA-------RVTVRLKDLD------------------SEEIKALVEEVRAFLAENFPPDGVEVTLT--GSA 593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 829 VVTAGIAEQMGDTFIQMgiaILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVVTGYTLGVSALMGMLMLVG 908
Cdd:COG1033 594 VLFAAINESVIESQIRS---LLLALLLIFLLLLLAFRSLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALG 670
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 909 IVLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMALSVSSGTmlsAELAIVVIGGMISSTFL 988
Cdd:COG1033 671 IGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSSFPPL---ADFGLLLALGLLVALLA 747
|
730
....*....|....
gi 499629239 989 TLFVIPAVYSMVYR 1002
Cdd:COG1033 748 ALLLLPALLLLLDP 761
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
697-1003 |
2.88e-18 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 90.43 E-value: 2.88e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 697 IAVDPAKVATSGLSPAQLAQLQQEFVLLMNGGALPGTTITlgsgsypvYFKGIAGRLSDAEQAKNLKIGFPVS--VTLND 774
Cdd:pfam00873 186 IWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQ--------ALIRAQGQLQSAEDFEKIIVKNQDGspVRLRD 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 775 IAFVGVVAEPSHVSHTDTMLSATITG--LITEANVGAVNAAVQEQVDAL-PSHP-GVKVVTAGiaeqmgDT--FIQMGIA 848
Cdd:pfam00873 258 VATVELGSELYRGFATFNGKPAVGLGvqKLPGANAIETADAVRAKLAELkPTFPqGVEIVVVY------DTtpFIRASIE 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 849 -----ILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVVTGYTLGVSALMGMLMLVGIVLTNAIVLVSMVEQ 923
Cdd:pfam00873 332 evvktLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDAIVVVENIER 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 924 Q-RKHGLSVKDALIEGGKIRLRPIVMTALTTILAMIPMA-LSVSSGTMLsAELAIVVIGGMISSTFLTLFVIPAVYSMVY 1001
Cdd:pfam00873 412 VlEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILfLGGLTGRIF-RQFAITIVLAILLSVLVALTLTPALCATLL 490
|
..
gi 499629239 1002 RG 1003
Cdd:pfam00873 491 KP 492
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
792-1004 |
3.17e-18 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 90.30 E-value: 3.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 792 TMLSATI--TGLITEANVGAVNAAVQEQVDALPShPGVKVVTAG---IAEQMGDTFIQ-MGIAILVAIAIVFLIVILMMR 865
Cdd:COG1033 162 TLIVVTLdpDPLSSDLDRKEVVAEIRAIIAKYED-PGVEVYLTGfpvLRGDIAEAIQSdLAIFFPLALLLILLLLFLFFR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 866 SIRNPLLIMLSIPLAFIGSMLALVVTGYTLGVSALMGMLMLVGIVLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRP 945
Cdd:COG1033 241 SLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPP 320
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 499629239 946 IVMTALTTILAMipMALSVSSGTMLSaELAIVVIGGMISSTFLTLFVIPAVYSMVYRGK 1004
Cdd:COG1033 321 VLLTSLTTAIGF--LSLLFSDIPPIR-DFGIVAAIGVLLAFLTSLTLLPALLSLLPRPK 376
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
268-474 |
3.72e-17 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 86.84 E-value: 3.72e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 268 ISVVKTESANTVETANAINEKIAELQGTLGDGVTIStvfdqsdfiGTS------ISQLEEKAIVGGILAVLVVFFFLWA- 340
Cdd:COG1033 555 VRLKDLDSEEIKALVEEVRAFLAENFPPDGVEVTLT---------GSAvlfaaiNESVIESQIRSLLLALLLIFLLLLLa 625
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 341 ---VRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVIIEVIYRRLRAGESFKEAAIGGAKEVA 417
Cdd:COG1033 626 frsLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTG 705
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 499629239 418 TPITTATLATVAIFAPLMF--VGGIVGemfvpFALTVTFAMLASLIVALTLIPALSKWL 474
Cdd:COG1033 706 KAILFTSLTLAAGFGVLLFssFPPLAD-----FGLLLALGLLVALLAALLLLPALLLLL 759
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
308-550 |
3.48e-11 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 67.18 E-value: 3.48e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 308 QSDFIGtsiSQLEEKAIVGGILAVLV--VFFFLWAV----RASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAV 381
Cdd:PRK13024 252 ESRSVG---PTLGQDAIDAGIIAGIIgfALIFLFMLvyygLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGI 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 382 GRLIDDSIVIIEVIYRRLRAGESFKEAAIGGAKEVATPITTATLATVaIFAPLMFV---GGIVGemfvpFALTVTFAMLA 458
Cdd:PRK13024 329 GMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNITTL-IAAAILFFfgtGPVKG-----FATTLIIGILA 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 459 SLIVALTLIPALSKWLVSSKQKVVIA---KDNWYQKVYIKALKWT----LGHRLAVVATAVLLLIGSAGLLPM----AGT 527
Cdd:PRK13024 403 SLFTAVFLTRLLLELLVKRGDKKPFLfgvKKKKIHNINEGVTIFDridfVKKRKWFLIFSIVLVIAGIIIFFIfglnLGI 482
|
250 260
....*....|....*....|...
gi 499629239 528 SFMSGSfgeeTISISISLPATAD 550
Cdd:PRK13024 483 DFTGGT----RYEIRTDQPVDLE 501
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
239-481 |
4.75e-10 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 64.01 E-value: 4.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 239 IKLSDIATISLSPSPSSaITRTNGKPSVGISV-VKTESANTV--ETANAINEKIAELQGTLgdgVTISTVFDQSDFIGTS 315
Cdd:TIGR00914 804 IPLSDVADLRVSPGPNQ-ISRENGKRRVVVSAnVRGRDLGSFvdDAKKAIAEQVKLPPGYW---ITWGGQFEQLQSATKR 879
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 316 IsqleeKAIVGgiLAVLVVFFFLWA----VRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVI 391
Cdd:TIGR00914 880 L-----QIVVP--VTLLLIFVLLYAafgnVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVM 952
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 392 IEVIYRRLRAGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGGIVGEMFVPFALTVTFAMLASLIVALTLIPALS 471
Cdd:TIGR00914 953 ISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALY 1032
|
250
....*....|
gi 499629239 472 KWLVSSKQKV 481
Cdd:TIGR00914 1033 RLVHRRRHKG 1042
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
675-1004 |
3.03e-09 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 61.32 E-value: 3.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 675 LKGVDGLEELKSdLTTVVPVLNIAVDPAKVATSGLSPAQLAQlqqefVLLMNGGALPGTTITLGSGSYPVYfkgIAGRLS 754
Cdd:TIGR00914 175 LRTVPGVAEVNS-IGGYVKQFLVAPDPEKLAAYGLSLADVVN-----ALERNNQNVGAGYIERRGEQYLVR---APGQVQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 755 DAEQAKN--LKIGFPVSVTLNDIAFVGVVAE----PSHVSHTDTMLSATItgLITEANVGAVNAAVQEQVDALPSH--PG 826
Cdd:TIGR00914 246 SMDDIRNivIATGEGVPIRIRDVARVQIGKElrtgAATENGKEVVLGTVF--MLIGENSRTVAQAVGDKLETINKTlpEG 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 827 VKVVTAGIAEQMGDTFIQMGIAILVAIAIVFLIVI-LMMRSIRNPLLIMLSIPLafigSMLALVVTGYTLGVSA-LMGML 904
Cdd:TIGR00914 324 VEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILfLFLGNIRAALIAATVIPL----SLLITFIGMVFQGISAnLMSLG 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 905 ML-VGIVLTNAIVLVS-----MVEQQRKHG--LSVKDAL---IEGGKIRLRPIVMTALTTILAMIP-MALSVSSGTMLSA 972
Cdd:TIGR00914 400 ALdFGLIVDGAVVIVEnahrrLAEAQHHHGrqLTLKERLhevFAASREVRRPLIFGQLIITLVFLPiFTLTGVEGKMFHP 479
|
330 340 350
....*....|....*....|....*....|..
gi 499629239 973 eLAIVVIGGMISSTFLTLFVIPAVYSMVYRGK 1004
Cdd:TIGR00914 480 -MAFTVVLALAGAMILSLTFVPAAVALFIRGK 510
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
792-996 |
6.69e-09 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 59.78 E-value: 6.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 792 TMLSATITGLITEANVGAVnAAVQEQVDALPShPGVKVVTAG---IAEQMGDTFIQ-MGIAILVAIAIVFLIVILMMRSI 867
Cdd:COG2409 116 ALVTVTLDGDAGDEAAEAV-DALRDAVAAAPA-PGLTVYVTGpaaLAADLNEAFEEdLGRAELITLPVALVVLLLVFRSL 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 868 RNPLLIMLSIPLAFIGSMLALVVTGYTLGVSA-LMGMLMLVGI-VLTN-AIVLVSMVEQQRKHGLSVKDALIEGGKIRLR 944
Cdd:COG2409 194 VAALLPLLTAGLAVGVALGLLALLAAFTDVSSfAPNLLTMLGLgVGIDyALFLVSRYREELRAGEDREEAVARAVATAGR 273
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 499629239 945 PIVMTALTTILAMipMALSVSSGTMLSAeLAIVVIGGMISSTFLTLFVIPAV 996
Cdd:COG2409 274 AVLFSGLTVAIAL--LGLLLAGLPFLRS-MGPAAAIGVAVAVLAALTLLPAL 322
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
322-475 |
7.83e-09 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 58.84 E-value: 7.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 322 KAIVGGILAVLVvFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVIIEVIYRRLRA 401
Cdd:TIGR01129 252 KAGLIGLVLVLV-FMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRL 330
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499629239 402 GESFKEAAIGGAKEVATPITTATLAT--VAIFAPLMFVGGIVGemfvpFALTVTFAMLASLIVALTlipaLSKWLV 475
Cdd:TIGR01129 331 GKSVRQAIEAGFERAFSTIFDANITTliAALILYVFGTGPVKG-----FAVTLAIGIIASLFTALV----FTRLLL 397
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
825-996 |
9.51e-08 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 56.00 E-value: 9.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 825 PGVKVVTAG-------IAEQMGDTfiqMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALVVTGYTLGV 897
Cdd:TIGR00921 171 SGKFLDVTGspainydIEREFGKD---MGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYA 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 898 SALMGMLMLVGIVLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMipMALSVSSGTMLSaELAIV 977
Cdd:TIGR00921 248 TTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGF--AALALSEFPMVS-EFGLG 324
|
170
....*....|....*....
gi 499629239 978 VIGGMISSTFLTLFVIPAV 996
Cdd:TIGR00921 325 LVAGLITAYLLTLLVLPAL 343
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
276-1002 |
1.32e-07 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 55.75 E-value: 1.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 276 ANTVETANAINEKIAEL-QGTLGDGVT------ISTVFDQSDFIGTSISQLEekAIVGGILAVLVVFFFLWAVRAsLIAA 348
Cdd:TIGR00833 128 KGQKEAQEAINAVRRIVeQTNAPDGLTvhvtgpLATIADILESGDKDMNRIT--ATTGIIVLIILLLVYRSPITM-LVPL 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 349 ISIPLSIFFGFLCMSLFG----ITLNILTLSAMT-IAVGRLIDDSIVIIEVIYRRLRAGESFKEAAIGGAKEVATPITTA 423
Cdd:TIGR00833 205 VSVGFSVVVAQGIVSLLGipglIGVNAQTTVLLTaLVIGAGTDYAVFLTGRYHEERRKGESLEEAAAEALRGTGKAILGS 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 424 TLATVAIFAPLMFVggiVGEMFVPFALTVTFAMLASLIVALTLIPAL----SKWLVSSKQKVVIAKDNWyQKVYIKALKW 499
Cdd:TIGR00833 285 ALTVAVAFLALSLA---RLPSFKTLGVSCAVGVLVALLNAVTLTPALltleGREGLMKPGRKSKIRFIW-RRLGTAVVRR 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 500 TLGHRLAVVATAVLLLIGSAGL---------LPMAGTS----------FMSGSFGEETISI--SISLPATADVSATSALT 558
Cdd:TIGR00833 361 PWPILVTTLIISGVSLLALPLIrtgyddekmIPTDLESvqgyeaadrhFPGNSMDPMVVMIksDHDVRNPALLADIDRFE 440
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 559 AKVEALLGANpSVRSYSSTIGTSATSMAGIMSASQGGGGANTASIIV------YLNSDADLQTELSNITLASQGITTDG- 631
Cdd:TIGR00833 441 REIKAVPGIN-MVQETQRPDGVVIKKTYLTFQAGNLGDQLDEFSDQLtsrqayLLQDAEKIAEAIAGLRLVQAGMRLDGe 519
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 632 ----VIQVSSGSGDSMGGSISSSSINLSIQGQNREEIAS--------ITAQLLEMLKGVDGLEELKSDLTTVVPVLNIAV 699
Cdd:TIGR00833 520 nlgqVSLAVRLMQQAISKLQGSAGDVFDIFDPLRRFVAAipecranpVCSVAREIVQAADTVVSSAAKLADAAGQLARGI 599
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 700 DPAKVATSGLSPAQLAQLQQEFVLLMNGGALPGttITLGSGSYPVYFKGIaGRLSDAeqAKNLKIGFPVSVTLNDIAFVG 779
Cdd:TIGR00833 600 ADVASALSQVSGLPNALDGIGTQLAQMRESAAG--VQDLLNELSDYSMTM-GKLKGN--AMGVDFYAPPRIFTDPNFKAV 674
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 780 VVAEPSHVSHTDTMLSATITGLITEANVGAVNAAVQEQVDALPSH--PGVKVVTAGIAEQMGD----TFIQMGIAILVAI 853
Cdd:TIGR00833 675 LDYFLSPDGHAARLLVYGDGSPAGDQGAQEFNAIRTVAEEAIQRAdlEPAKVELAGVSAVNRDlrdlVNSDLGLISIITL 754
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 854 AIVFLIVILMMRSIRNPLLIMLSIPLAFIGSM-LALVVTGYTLGVSA-----LMGMLMLVGIVLTNAIVLVSMVEQQRKH 927
Cdd:TIGR00833 755 AIVFMILALLLRAPVAPIVLIGSVALSYLWALgLSVLAFQHILGAELhwsvlAGVFVLLVALGVDYNMLLVSRIKEESPA 834
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499629239 928 GL--SVKDALIEGGKirlrpiVMTALTTILAMIPMALSVSSGTMLsAELAIVVIGGMISSTFLT-LFVIPAVYSMVYR 1002
Cdd:TIGR00833 835 GNrtGIIRALGSTGG------VITAAGLVFAGTMAALASAQLTAI-AQFGFTVGVGILLDTFIVrSVTVPALTLLLGR 905
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
317-523 |
1.97e-07 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 55.39 E-value: 1.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 317 SQLEEKAIVGGILA-VLVVFFFLWAVRA-SLIAAISIPLsiFFGFLCMSLFGI----TLNILTLSAMTIAVGRLIDDSIV 390
Cdd:TIGR03480 265 ATVSEGATVAGLLSfVLVLVLLWLALRSpRLVFAVLVTL--IVGLILTAAFATlavgHLNLISVAFAVLFIGLGVDFAIQ 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 391 IIeVIYRRLR-AGESFKEAAIGGAKEVATPITTATLATVA---IFAPLMFVGgiVGEMfvpfALTVTFAMLASLIVALTL 466
Cdd:TIGR03480 343 FS-LRYREERfRGGNHREALSVAARRMGAALLLAALATAAgffAFLPTDYKG--VSEL----GIIAGTGMFIALFVTLTV 415
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499629239 467 IPALSKWLVSSKQKvviakdnwyQKVYIKALK----WTLGHRLAVVATAVLLLIGSAGLLP 523
Cdd:TIGR03480 416 LPALLRLLRPPRRR---------KPPGYATLApldaFLRRHRRPVLGVTLILGIAALALLP 467
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
803-997 |
2.05e-07 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 55.24 E-value: 2.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 803 TEANVGAVNAAVQEQVDALPSHPGVKVVTAG---IAEQMGDTfIQMGIAILVAIAIVFLIVILMM--RSIRNPLLIMLSI 877
Cdd:COG4258 205 TDAQQQLVAALRAAFAALNAAFPGAQLLLTGaglFAVAAAQQ-IKHDISTIGLISLLGILLLLLLvfRSLRPLLLGLLPV 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 878 plaFIGSMLALVVTGYTLG-VSAL---MGMlMLVGIVLTNAIVLVSmvEQQRKHGLSVKDALiegGKIRlRPIVMTALTT 953
Cdd:COG4258 284 ---AVGALAGLAAVSLVFGsVHGItlgFGS-SLIGVAVDYSLHYLT--HRRAAGEWDPRAAL---RRIW-PTLLLGLLTT 353
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 499629239 954 ILAMIPMALSVSSGTmlsAELAIVVIGGMISSTFLTLFVIPAVY 997
Cdd:COG4258 354 VLGYLALLFSPFPGL---RQLGVFAAAGLLAAALTTLLWLPLLL 394
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
812-1002 |
2.19e-07 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 53.83 E-value: 2.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 812 AAVQEQVDALPSHPGVKVVTAGIAEQMGDTFI----QMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLA 887
Cdd:pfam03176 107 AAVRDAVEQAPPPEGLKAYLTGPAATVADLRDagdrDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAQGL 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 888 LVVTGYTLGV-----SALMGMLMLVGIVLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRPIVMTALTTILAMipMAL 962
Cdd:pfam03176 187 VAILAHILGIglstfALNLLVVLLIAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAM--LAL 264
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 499629239 963 SVSSGTMLSAeLAIVVIGGMISSTFLTLFVIPAVYSMVYR 1002
Cdd:pfam03176 265 SFARLPVFAQ-VGPTIAIGVLVDVLAALTLLPALLALLGR 303
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
804-996 |
2.53e-07 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 55.00 E-value: 2.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 804 EANVGAVNAAVQEQvdALPSHPGVKV-VTAGIA---EQMGDTFIQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPL 879
Cdd:TIGR03480 228 EKAINAIRAAAKDL--RLDEDHGVTVrLTGEVAlsdEELATVSEGATVAGLLSFVLVLVLLWLALRSPRLVFAVLVTLIV 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 880 AFIGSM-LALVVTGyTLGVSALMGMLMLVGIVLTNAIVLVSMVEQQRKHGLSVKDALIEGGKIRLRPIVMTALTT---IL 955
Cdd:TIGR03480 306 GLILTAaFATLAVG-HLNLISVAFAVLFIGLGVDFAIQFSLRYREERFRGGNHREALSVAARRMGAALLLAALATaagFF 384
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 499629239 956 AMIPMALsvsSGTmlsAELAIVVIGGMISSTFLTLFVIPAV 996
Cdd:TIGR03480 385 AFLPTDY---KGV---SELGIIAGTGMFIALFVTLTVLPAL 419
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
265-612 |
3.77e-07 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 54.00 E-value: 3.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 265 SVGISVVKTESANTVETANAINEKIAELQGTLGDGVTIS---TVFDQSDFIGTSISQLeekaIVGGILAVLVVFFFLWAV 341
Cdd:COG2409 114 KAALVTVTLDGDAGDEAAEAVDALRDAVAAAPAPGLTVYvtgPAALAADLNEAFEEDL----GRAELITLPVALVVLLLV 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 342 RASLIAAIsIPL-----SIFFGFLCMSLFG--ITLNILTLSAMT---IAVGrlIDDSIVIIeVIYRR-LRAGESFKEAAI 410
Cdd:COG2409 190 FRSLVAAL-LPLltaglAVGVALGLLALLAafTDVSSFAPNLLTmlgLGVG--IDYALFLV-SRYREeLRAGEDREEAVA 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 411 GGAKEVATPITTATLaTVAI-FAPLMFVG-GIVGEMFVPFALTVTFAMLAslivALTLIPAL----SKWLVSSKQKVVIA 484
Cdd:COG2409 266 RAVATAGRAVLFSGL-TVAIaLLGLLLAGlPFLRSMGPAAAIGVAVAVLA----ALTLLPALlallGRRVFWPRRPRRRR 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 485 KDNWYQKVYIKALKWTLGHRLAVVATAVLLLIgsAGLLPMAGTSFmsgsfgeeTISISISLPATADV------------- 551
Cdd:COG2409 341 AAAPESGFWRRLARAVVRRPVPVLVAAVAVLL--ALALPALGLRL--------GLPDADSLPADSPSrqgydalaehfpp 410
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499629239 552 SATSALTAKVEALLGANPSVRSYSSTIGTSATSMAGIMSASQ----GGGGANTASIIVYLNSDAD 612
Cdd:COG2409 411 GSNGPLTVVVESDDDLDPADLAALDALAAALAAVPGVASVQPptrpEGTDGDAARLQVVPDGDPD 475
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
221-521 |
4.38e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 54.07 E-value: 4.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 221 TNYSSLSDIEQISLGGDDIKLSDIA-TISLSPSPSSAITRTNGKPSVGISVVKTESANT--------------VETANAI 285
Cdd:TIGR00921 91 TNVRSAADIMRQIPGNFPLPVTMPEvRPLMSEYPRSKEMFLSKDHTVAIIIVQLKSDADykqvvpiyndversLERTNPP 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 286 NEKIAELQGTLGDGVTISTVFDQSDFIGTSISqleekaivgGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLF 365
Cdd:TIGR00921 171 SGKFLDVTGSPAINYDIEREFGKDMGTTMAIS---------GILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWL 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 366 GITLNILTLSAMTIAVGRLIDDSIVIIEVIYRRLRAGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVG-GIVGEM 444
Cdd:TIGR00921 242 GIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEfPMVSEF 321
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499629239 445 FVPFALTVTFAMLASLIVALTLIPALSKWLVSSKQKVVIAKDNWYQKVYIKALKWTLGHRLAVVATAVLLLIGSAGL 521
Cdd:TIGR00921 322 GLGLVAGLITAYLLTLLVLPALLQSIDIGREKVKKEIIAIGGKSSEIEEELSKVLSITVRHPVPALVAALIITGLGL 398
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
812-995 |
5.61e-07 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 53.70 E-value: 5.61e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 812 AAVQEQVDALPshpGVKVV--TAGIAEQMGDTFIQMGIAILVAIAIVFLIVILMMRSIRNPLLIMLSIPLAFIGSMLALV 889
Cdd:COG4258 609 AALRAAAAGLP---GVRLVdrKAESSSLFGRYRNDALWLLLLALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILG 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 890 VTGYTLGVSALMGMLMLVGIVLTNAIVlvsMVEQQRKHglsvkdaliEGGKIRLRPIVMTALTTILAMipMALSVSSGTM 969
Cdd:COG4258 686 LLGIPLNLFHLIALLLVLGIGIDYALF---FTEGLLDK---------GELARTLLSILLAALTTLLGF--GLLAFSSTPA 751
|
170 180
....*....|....*....|....*.
gi 499629239 970 LSAeLAIVVIGGMISSTFLTLFVIPA 995
Cdd:COG4258 752 LRS-FGLTVLLGILLALLLAPLLAPR 776
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
317-464 |
1.94e-06 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 49.56 E-value: 1.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 317 SQLEEKAIVGGILAVLVVFFFLWAV--RASLIAAISIPLS-IFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVIIE 393
Cdd:TIGR00916 43 GELIKAGIIALLIGLVLVLLYMLLRyeWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFD 122
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499629239 394 VIYRRLRA--GESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGG--IVGemfvpFALTVTFAMLASLIVAL 464
Cdd:TIGR00916 123 RIREELRKykGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGgaIKG-----FALTLGIGVIAGTYSSI 192
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
322-481 |
2.36e-06 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 51.38 E-value: 2.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 322 KAIVGGILAVlVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITlniLTLS---AMTIAVGRLIDDSIVIIEVIYRR 398
Cdd:PRK05812 301 IAGLIGLALV-LLFMILYYRLFGLIANIALVANLVLILAVLSLLGAT---LTLPgiaGIVLTIGMAVDANVLIFERIREE 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 399 LRAGESFKEAAIGGAKEVATPITTA---TLATVAIfapLMFVG-GIV-GemfvpFALTVTFAMLASLIVALTLIPALSKW 473
Cdd:PRK05812 377 LREGRSLRSAIEAGFKRAFSTILDSnitTLIAAII---LYALGtGPVkG-----FAVTLGIGILTSMFTAITVTRALVNL 448
|
....*...
gi 499629239 474 LVSSKQKV 481
Cdd:PRK05812 449 LYGRRKRL 456
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
324-476 |
3.84e-06 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 50.87 E-value: 3.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 324 IVGGILAVLVVFFFLWAVR-ASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVIIEVIYRRLRAG 402
Cdd:PRK14726 376 VAGLIAAILVAALMIGFYGfLGVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTG 455
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499629239 403 ESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGgivGEMFVPFALTVTFAMLASLIVALTlipaLSKWLVS 476
Cdd:PRK14726 456 HSLIQALDRGFSRALATIVDANVTILIAAVILFFLG---SGAVRGFAVTLAVGILTTVFTAFT----LTRSLVA 522
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
811-983 |
4.09e-05 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 47.68 E-value: 4.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 811 NAAVQEQVDAL----PSHPGVKVVTAGIAEQMGDTFIQMGIAILVAIAIVFLIvilMMRSIRNPLLIMLSIPLAFIGSML 886
Cdd:TIGR03480 679 NEALRRFVRAVrkvaPDATGAPVSILESGDTVVGAFLQAFIYALVAITVLLLL---TLRRVRDVLLVLAPLLLAGLLTVA 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 887 ALVVTGYTLGVSALMGMLMLVGIVLTNAIVLVSMVEQQRKHGlsvkdALIEGGKIrlRPIVMTALTTILAMIPMALS--- 963
Cdd:TIGR03480 756 AMVLLGIPFNFANIIALPLLLGLGVDFGIYMVHRWRNGVDSG-----NLLQSSTA--RAVFFSALTTATAFGSLAVSshp 828
|
170 180
....*....|....*....|..
gi 499629239 964 --VSSGTMLSAELAIVVIGGMI 983
Cdd:TIGR03480 829 gtASMGILLSLGLGLTLLCTLI 850
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
321-478 |
4.31e-05 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 47.03 E-value: 4.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 321 EKAIVGGILAVLVVFFFLWAV--RASLIAAISIPLSIFFGFLCMSLFGITLnilTLS---AMTIAVGRLIDDSIVIIEVI 395
Cdd:COG0342 271 EKGLIAGLIGLLLVALFMLLYyrLPGLVANIALALNVVLLLGVLSLLGATL---TLPgiaGIILTIGMAVDANVLIFERI 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 396 YRRLRAGESFKEA----------AIGGAKevatpITTAtLATVAIFAplMFVGGIVGemfvpFALTVTFAMLASLIVALT 465
Cdd:COG0342 348 REELRAGRSLRAAieagfkrafsTILDAN-----VTTL-IAAVVLFV--LGTGPVKG-----FAVTLILGILISMFTAVP 414
|
170
....*....|...
gi 499629239 466 LIPALSKWLVSSK 478
Cdd:COG0342 415 VTRPLLNLLLGRR 427
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
324-470 |
6.88e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 46.75 E-value: 6.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 324 IVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVIIEViYRRLRAGE 403
Cdd:TIGR00921 574 IAGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHLAER-YFEERKEH 652
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499629239 404 SFKEAAIGGAKEVATPITTATLATVAIFAPLMFVggiVGEMFVPFALTVTFAMLASLIVALTLIPAL 470
Cdd:TIGR00921 653 GPKEAITHTMERTGPGILFSGLTTAGGFLSLLLS---HFPIMRNFGLVQGIGVLSSLTAALVVFPAL 716
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
327-470 |
2.23e-04 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 44.59 E-value: 2.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 327 GILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLC--------MSLFGITLNILT---LSAMTIAVGrlIDDSIVIIEVI 395
Cdd:pfam03176 148 EAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAaqglvailAHILGIGLSTFAlnlLVVLLIAVG--TDYALFLVSRY 225
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 499629239 396 YRRLRAGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVG-GIVGEMFVPFALTVTFAMLAslivALTLIPAL 470
Cdd:pfam03176 226 REELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARlPVFAQVGPTIAIGVLVDVLA----ALTLLPAL 297
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
304-470 |
3.10e-04 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 44.65 E-value: 3.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 304 TVFDQSDFIGTSISQLEEKAIVGGILAVLVVFFFLWAVRASLIAAISIPLSI------FFGFlcMSLFGITLNILTLSAM 377
Cdd:pfam02460 622 TVFDEDAPFADQYLTILPSTIQNIVITLICMFIVCFLFIPNPPCVFVITLAIasidigVFGF--LSLWGVDLDPISMITI 699
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 378 TIAVGRLIDDSIVIIEVIYRRlrAGESFKEAAIGGAKEVATPITTATLATVAifaplmfvgGIVGEMFVPFALTVTFAML 457
Cdd:pfam02460 700 IMSIGFSVDFSAHIAYHFVRS--RGDTPAERVVDALEALGWPVFQGGLSTIL---------GVLVLLFVPSYMVVVFFKT 768
|
170
....*....|...
gi 499629239 458 ASLIVALTLIPAL 470
Cdd:pfam02460 769 VFLVVAIGLLHGL 781
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
253-463 |
3.99e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 44.45 E-value: 3.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 253 PSSAITRTNGKPSVGISVVKTESANTvetaNAINEKIAELQGTLGDGVTISTVfdQSDFIGTSISQ-LEEKAIVGGILAV 331
Cdd:PRK13024 514 EVNIVTFGSDNNQVLVRTYGILSDDE----EADTEIVAKLKNALKNDKGGTIP--SSETVGPTVGKeLARNAIIAVLIAL 587
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 332 LVVFFFLWA---VRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVIIEVI--YRRLRAGESFK 406
Cdd:PRK13024 588 IGILLYILIrfeWTFSLGAILALLHDVLIVIGFFSLFRLEVDLTFIAAILTIIGYSINDTVVVFDRIreNLRLYKKKDLR 667
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 499629239 407 EAAIGGAKEVATPITTATLATVAIFAPLMFVGgivGEMFVPFAltvtFAMLASLIVA 463
Cdd:PRK13024 668 EIVNKSINQTLSRTINTSLTTLLVLLALLIFG---GSSLRNFS----LALLVGLIVG 717
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
323-482 |
1.41e-03 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 42.68 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 323 AIVGGILAVLVVFFFLWAVRASL--IAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVIIEVIYRRLR 400
Cdd:PRK13023 280 AVLAALLAALVVGLFMVLSYGILgvIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRR 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 401 AGESFKEAAIGGAKEVATPITTATLATVaIFAPLMFVGGivGEMFVPFALTVTFAMLASLIVALTLIPAL-SKWLVSSKQ 479
Cdd:PRK13023 360 KGYSVVQAMESGFYRALSTIVDANLTTL-IAALVLFLLG--SGTVHGFALTVAIGIGTTLFTTLTFTRLLiAQWVRTAKP 436
|
...
gi 499629239 480 KVV 482
Cdd:PRK13023 437 KEV 439
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
324-467 |
1.56e-03 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 42.46 E-value: 1.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 324 IVGGILAVLVVFFFLWAVRASLIAAISIPLSIFFgflcMSLFGITLNILTLSAMTIAVGRLIDDSIVIIEVIYRRL-RAG 402
Cdd:NF037998 454 LAIAIMIYLLFAYRLLGLFAIIIALTSISLTLYS----PTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLyKNK 529
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499629239 403 ESFKEAAIGGAKEVATPITTATLATVaIFAPLMF-VG-GIVGEMFVPFALTVTFAMLASLIVALTLI 467
Cdd:NF037998 530 RSIEESFKIANKETIGIIVDALVVLL-IPNLSLFwIGsNSIKSFATILLVGVIISLVLVIIVARLMI 595
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
325-469 |
1.78e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 42.15 E-value: 1.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 325 VGGILAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVIIEVIYRRLRAGES 404
Cdd:COG4258 647 LALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFFTEGLLDKGELART 726
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 499629239 405 FkeaaiggakevaTPITTATLATVAIFAPLMFVGgivgemfVP----FALTVTFAMLASLIVALTLIPA 469
Cdd:COG4258 727 L------------LSILLAALTTLLGFGLLAFSS-------TPalrsFGLTVLLGILLALLLAPLLAPR 776
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
825-997 |
3.65e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 41.36 E-value: 3.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 825 PGVKVVTAG---IAEQMGDTFIQ-MGIAILVAIAIVFLIVILMMRSIRN---PLLIMLSIPLAFIGSMlALVVTGYTLGV 897
Cdd:TIGR00921 545 PGVKVGVTGlpvAFAEMHELVNEgMRRMTIAGAILVLMILLAVFRNPIKavfPLIAIGSGILWAIGLM-GLRGIPSFLAM 623
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 898 SALMGMLMLVGIvlTNAIVLVSMVEQQRKhGLSVKDALIEGGKIRLRPIVMTALTTILAMipMALSVSSGTMLSaELAIV 977
Cdd:TIGR00921 624 ATTISIILGLGM--DYSIHLAERYFEERK-EHGPKEAITHTMERTGPGILFSGLTTAGGF--LSLLLSHFPIMR-NFGLV 697
|
170 180
....*....|....*....|
gi 499629239 978 VIGGMISSTFLTLFVIPAVY 997
Cdd:TIGR00921 698 QGIGVLSSLTAALVVFPALL 717
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
329-464 |
3.74e-03 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 41.38 E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 329 LAVLVVFFFLWAVRASLIAAISIPLSIFFGFLCMSLFGITLNILTLSAMTIAVGRLIDDSIVIIEVIYRRLRAGESFKEA 408
Cdd:PRK12911 919 LAVLIVLMSVYYRFGGVIASGAVLLNLLLIWAALQYLDAPLTLSGLAGIVLAMGMAVDANVLVFERIREEYLLSRSLSES 998
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 499629239 409 AIGGAKEVATPITTATLATVAIFAPLMFV--GGIVGemfvpFALTVTFAMLASLIVAL 464
Cdd:PRK12911 999 VEAGYKKAFSAIFDSNLTTILASALLLMLdtGPIKG-----FALTLIIGIFSSMFTAL 1051
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
288-473 |
7.01e-03 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 38.74 E-value: 7.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 288 KIAELQGTLGDGVTIStvfdqSDFIGTSIS-QLEEKAIVGGILAVLVVFF-----FLWAVRASLIAAISIPLSIFFGFlc 361
Cdd:pfam02355 2 VEALLKNVGPDAEIIS-----IETVGPTVGsELARKAVLALLFALLLILIyvglrFEWRFALGAIIALAHDVIITVGV-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499629239 362 MSLFGITLNILTLSAMTIAVGRLIDDSIVIIEVIYRRLR--AGESFKEAAIGGAKEVATPITTATLATVAIFAPLMFVGg 439
Cdd:pfam02355 75 FSLFGIEVDLATVAALLTIIGYSVNDTVVVFDRVRENLRkkTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFG- 153
|
170 180 190
....*....|....*....|....*....|....*...
gi 499629239 440 ivGEMFVPFALTVTFAMLA----SLIVALTLIPALSKW 473
Cdd:pfam02355 154 --GGSLKDFSLALLVGVIVgtysSIFIASPILLDLGER 189
|
|
| |
