NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|499656302|ref|WP_011337036|]
View 

cell wall hydrolase [Cereibacter sphaeroides]

Protein Classification

cell wall hydrolase( domain architecture ID 11467324)

cell wall hydrolase similar to Bacillus proteins SleB and CwlJ, which are spore cortex-lytic enzymes involved in the depolymerization of cortex peptidoglycan during germination

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CwlJ COG3773
Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, ...
 115-237 5.46e-55

Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442987  Cd Length: 124  Bit Score: 172.28  E-value: 5.46e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656302 115 SDEWKCLATALYFEARGESIQGQFAVAEVIMNRVDRPGYPGSICGVVRQGGQFSFMFDGKPETIREKAAFqragKIAALM 194
Cdd:COG3773    5 DSDLDLLARAIYAEARGEPYEGQVAVAAVVLNRVRSPRFPNTICGVVYQPGQFSPVCDGQINRPPEEEAR----RAARDA 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 499656302 195 LAGAPRQLTQGATHFHTRA-VRPGWAHRFPRTAAIGAHLFYRQP 237
Cdd:COG3773   81 LNGWRRDPTGGALYFHNPAtVTPSWARSRPKTARIGNHVFYRPR 124
 
Name Accession Description Interval E-value
CwlJ COG3773
Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, ...
 115-237 5.46e-55

Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442987  Cd Length: 124  Bit Score: 172.28  E-value: 5.46e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656302 115 SDEWKCLATALYFEARGESIQGQFAVAEVIMNRVDRPGYPGSICGVVRQGGQFSFMFDGKPETIREKAAFqragKIAALM 194
Cdd:COG3773    5 DSDLDLLARAIYAEARGEPYEGQVAVAAVVLNRVRSPRFPNTICGVVYQPGQFSPVCDGQINRPPEEEAR----RAARDA 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 499656302 195 LAGAPRQLTQGATHFHTRA-VRPGWAHRFPRTAAIGAHLFYRQP 237
Cdd:COG3773   81 LNGWRRDPTGGALYFHNPAtVTPSWARSRPKTARIGNHVFYRPR 124
Hydrolase_2 pfam07486
Cell Wall Hydrolase; These enzymes have been implicated in cell wall hydrolysis, most ...
 131-234 3.72e-33

Cell Wall Hydrolase; These enzymes have been implicated in cell wall hydrolysis, most extensively in Bacillus subtilis. For instance Swiss:P50739 is expressed during sporulation as an inactive form and then deposited on the cell outer cortex. During germination the the enzyme is activated and hydrolyses the cortex. A similar role is carried out by the partially redundant Swiss:P42249. It is not clear whether these enzymes are amidases or peptidases.


Pssm-ID: 462179  Cd Length: 101  Bit Score: 115.69  E-value: 3.72e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656302  131 GESIQGQFAVAEVIMNRVDRPGYPGSICGVVRQGGQFSFMFDGKPetirEKAAFQRAGKIAALMLAGApRQLTQGATHFH 210
Cdd:pfam07486   1 GEPYEGQVAVANVILNRVRSPRFPNTICGVVYQPGQFSPVCDGRI----NLPPSEEAIRAARDALAGE-RDPTGGALYFH 75

                          90       100
                  ....*....|....*....|....*.
gi 499656302  211 TRAVRPG-WAH-RFPRTAAIGAHLFY 234
Cdd:pfam07486  76 NPSVAPSsWIWsRGVRTARIGNHVFY 101
 
Name Accession Description Interval E-value
CwlJ COG3773
Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, ...
 115-237 5.46e-55

Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442987  Cd Length: 124  Bit Score: 172.28  E-value: 5.46e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656302 115 SDEWKCLATALYFEARGESIQGQFAVAEVIMNRVDRPGYPGSICGVVRQGGQFSFMFDGKPETIREKAAFqragKIAALM 194
Cdd:COG3773    5 DSDLDLLARAIYAEARGEPYEGQVAVAAVVLNRVRSPRFPNTICGVVYQPGQFSPVCDGQINRPPEEEAR----RAARDA 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 499656302 195 LAGAPRQLTQGATHFHTRA-VRPGWAHRFPRTAAIGAHLFYRQP 237
Cdd:COG3773   81 LNGWRRDPTGGALYFHNPAtVTPSWARSRPKTARIGNHVFYRPR 124
Hydrolase_2 pfam07486
Cell Wall Hydrolase; These enzymes have been implicated in cell wall hydrolysis, most ...
 131-234 3.72e-33

Cell Wall Hydrolase; These enzymes have been implicated in cell wall hydrolysis, most extensively in Bacillus subtilis. For instance Swiss:P50739 is expressed during sporulation as an inactive form and then deposited on the cell outer cortex. During germination the the enzyme is activated and hydrolyses the cortex. A similar role is carried out by the partially redundant Swiss:P42249. It is not clear whether these enzymes are amidases or peptidases.


Pssm-ID: 462179  Cd Length: 101  Bit Score: 115.69  E-value: 3.72e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656302  131 GESIQGQFAVAEVIMNRVDRPGYPGSICGVVRQGGQFSFMFDGKPetirEKAAFQRAGKIAALMLAGApRQLTQGATHFH 210
Cdd:pfam07486   1 GEPYEGQVAVANVILNRVRSPRFPNTICGVVYQPGQFSPVCDGRI----NLPPSEEAIRAARDALAGE-RDPTGGALYFH 75

                          90       100
                  ....*....|....*....|....*.
gi 499656302  211 TRAVRPG-WAH-RFPRTAAIGAHLFY 234
Cdd:pfam07486  76 NPSVAPSsWIWsRGVRTARIGNHVFY 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH