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Conserved domains on  [gi|499656331|ref|WP_011337065|]
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CpaF family protein [Cereibacter sphaeroides]

Protein Classification

CpaF family protein( domain architecture ID 10008984)

CpaF family protein is an ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer; similar to Aggregatibacter actinomycetemcomitans TadA, a predicted secretion NTPase that is required for adherence

Gene Ontology:  GO:0005524|GO:0016887
PubMed:  11226268

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CpaF COG4962
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ...
 70-473 0e+00

Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 443988 [Multi-domain]  Cd Length: 386  Bit Score: 551.31  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  70 ELKVELHRRllddlnlaaletASESSLRSEIAAICGEALEEMSVVLNKDERAILNQELYDEVMGLGPLEPLLKDETINDI 149
Cdd:COG4962    4 ELVERVRRR------------LDREELREEVRAAVAEALRAEGLVLSDAEREALARAVLDELFGLGPLEPLLDDPDVTDI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 150 LVNGPYRIFVERSGKLELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLADGSRFNAMVPPIAVDGSLVSIRKF 229
Cdd:COG4962   72 MVNGPDEVFVERGGRLERTDVRFDSEEELRRLIERIAARVGRRLDESSPIVDARLPDGSRVNAVIPPVARDGPSLSIRKF 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 230 KKDKLGIADLVRFGAFTEEMAAYLQAAVATRLNIIVsggtgsgktttLNALSSFIDNSERILTIEDTAELQLQQAHVGRM 309
Cdd:COG4962  152 RKRPLTLEDLVALGSLTPEMAEFLRAAVRARLNILVsggtgsgkttlLNALSGFIPPDERIVTIEDAAELQLQHPHVVRL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 310 ESRPPNVEGKGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDMLQAMNTGHDGSMTTIHANSARDGISRLENMVAMAGIE 389
Cdd:COG4962  232 ETRPPNVEGAGEVTLRDLVRNALRMRPDRIIVGEVRGAEALDMLQAMNTGHDGSMSTLHANSARDALARLETLALMAGEN 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 390 MPIKAVRAQIASAVNLIVQASRLQDGSRRMVSITEITGMEGDVISMQEIFRYERLGVEPSGKIIGRFnatgvrshySDRF 469
Cdd:COG4962  312 LPREAVRRQIASAIDLVVHLERLRDGRRRVTEIAEVTGMEGGRVVLQPIFRFDPGGLDAAGGVRPRF---------LERL 382


                 ....
gi 499656331 470 RQWG 473
Cdd:COG4962  383 EAAG 386
 
Name Accession Description Interval E-value
CpaF COG4962
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ...
 70-473 0e+00

Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443988 [Multi-domain]  Cd Length: 386  Bit Score: 551.31  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  70 ELKVELHRRllddlnlaaletASESSLRSEIAAICGEALEEMSVVLNKDERAILNQELYDEVMGLGPLEPLLKDETINDI 149
Cdd:COG4962    4 ELVERVRRR------------LDREELREEVRAAVAEALRAEGLVLSDAEREALARAVLDELFGLGPLEPLLDDPDVTDI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 150 LVNGPYRIFVERSGKLELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLADGSRFNAMVPPIAVDGSLVSIRKF 229
Cdd:COG4962   72 MVNGPDEVFVERGGRLERTDVRFDSEEELRRLIERIAARVGRRLDESSPIVDARLPDGSRVNAVIPPVARDGPSLSIRKF 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 230 KKDKLGIADLVRFGAFTEEMAAYLQAAVATRLNIIVsggtgsgktttLNALSSFIDNSERILTIEDTAELQLQQAHVGRM 309
Cdd:COG4962  152 RKRPLTLEDLVALGSLTPEMAEFLRAAVRARLNILVsggtgsgkttlLNALSGFIPPDERIVTIEDAAELQLQHPHVVRL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 310 ESRPPNVEGKGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDMLQAMNTGHDGSMTTIHANSARDGISRLENMVAMAGIE 389
Cdd:COG4962  232 ETRPPNVEGAGEVTLRDLVRNALRMRPDRIIVGEVRGAEALDMLQAMNTGHDGSMSTLHANSARDALARLETLALMAGEN 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 390 MPIKAVRAQIASAVNLIVQASRLQDGSRRMVSITEITGMEGDVISMQEIFRYERLGVEPSGKIIGRFnatgvrshySDRF 469
Cdd:COG4962  312 LPREAVRRQIASAIDLVVHLERLRDGRRRVTEIAEVTGMEGGRVVLQPIFRFDPGGLDAAGGVRPRF---------LERL 382


                 ....
gi 499656331 470 RQWG 473
Cdd:COG4962  383 EAAG 386
heli_sec_ATPase TIGR03819
helicase/secretion neighborhood ATPase; Members of this protein family comprise a distinct ...
 125-422 8.20e-100

helicase/secretion neighborhood ATPase; Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.


Pssm-ID: 200328  Cd Length: 340  Bit Score: 303.10  E-value: 8.20e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  125 QELYDEVMGLGPLEPLLKDETINDILVNGPYRIFVERSGKLELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARL 204
Cdd:TIGR03819  43 RALRRDLVGAGPLEPLLADPGVTDVLVNGPDEVWVDRGRGLERTDVRFPDEAAVRRLAQRLAAAAGRRLDDAQPWVDARL 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  205 ADGSRFNAMVPPIAVDGSLVSIRKFKKDKLGIADLVRFGAFTEEMAAYLQAAVATRLNIIVSGGTGSGKTTTLNALSSFI 284
Cdd:TIGR03819 123 PDGTRLHAVLPPVATDGTCLSLRVPRRRTFTLDELVAAGTIPPGVARLLRALVAARLAFLVSGGTGSGKTTLLSALLALV 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  285 DNSERILTIEDTAELQLQQAHVGRMESRPPNVEGKGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDMLQAMNTGHDGSM 364
Cdd:TIGR03819 203 PPDERIVLVEDAAELRPDHPHVVRLEARPANVEGAGAVTLTDLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHDGGA 282

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 499656331  365 TTIHANSARDGISRLENMVAMAGieMPIKAVRAQIASAVNLIVQASRLQDGSRRMVSI 422
Cdd:TIGR03819 283 GTLHANSPADVPARLEALGALAG--LDRAALHSQLAAALDVVLHVRRTPRGRRRVAEI 338
VirB11-like_ATPase cd01130
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ...
 249-426 3.26e-72

Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.


Pssm-ID: 410874 [Multi-domain]  Cd Length: 177  Bit Score: 226.27  E-value: 3.26e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 249 MAAYLQAAVATRLNIIVSGGTGSGKTTTLNALSSFIDNSERILTIEDTAELQLQQAHVGRMESRPPNVEgKGAVTQRDCL 328
Cdd:cd01130    1 MAAFLRLAVRARKNILISGGTGSGKTTLLNALLSFIPPDERIVTIEDTRELQLPHPNVVHLLTRPGGGE-KGEVTMADLL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 329 RNALRMRPDRIIVGETRGEEVIDMLQAMNTGHDGSMTTIHANSARDGISRLENMVAMAGIEMPIKAVRAQIASAVNLIVQ 408
Cdd:cd01130   80 KAALRMRPDRIIVGEVRGGEAYDMLQAMNTGHPGSITTIHANSAEDAIDRLATLVLEAGVNLDEEALRRLIASAIDVIVH 159

                        170
                 ....*....|....*...
gi 499656331 409 ASRLQDGSRRMVSITEIT 426
Cdd:cd01130  160 VKRLGDGVRRVTEIYEVP 177
T2SSE pfam00437
Type II/IV secretion system protein; This family contains components of both the Type II ...
 133-398 9.22e-54

Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.


Pssm-ID: 425681 [Multi-domain]  Cd Length: 269  Bit Score: 181.71  E-value: 9.22e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  133 GLGPLEPLlkDETINDILVNGPYRIFV--ERSGKlELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLA----- 205
Cdd:pfam00437   1 NLIPLEAL--DEGASDIHVEPPERIVWirFRVDG-VLREIPFPDADALARLISRIKVMARLDISERRPPQDGRLPlrigg 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  206 DGSRFNAMVPPIAVDGSLVsIRKFKKD--KLGIADLVRFGAFTEEMAAYLQAAvatRLNIIVSGGTGSGKTTTLNALSSF 283
Cdd:pfam00437  78 KGVRVRVSTLPTAGGEKLV-IRLLDPSnvALSLDELGMTGAQDEALLEFLRQP---RGNILVTGPTGSGKTTTLYAALGE 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  284 IDNS-ERILTIEDTAELQLQQAHVGRMESRppnvegkGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDM-LQAMNTGHD 361
Cdd:pfam00437 154 LNTRdENIVTVEDPVEIQLEGINQVQLNAR-------AGVTFADLLRAILRQDPDRIMVGEIRDLETAEIaLQAANTGHL 226

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 499656331  362 GsMTTIHANSARDGISRLENM-VAMAGIEMPIKAVRAQ 398
Cdd:pfam00437 227 V-LSTLHTNSAAGALTRLQDMgVPPFELASSLLLVIAQ 263
PRK13900 PRK13900
type IV secretion system ATPase VirB11; Provisional
 134-425 6.52e-40

type IV secretion system ATPase VirB11; Provisional


Pssm-ID: 184381  Cd Length: 332  Bit Score: 146.83  E-value: 6.52e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 134 LGPLEPLLKDETINDILVNGPYRIFVERSGKLELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLADGSRFNAM 213
Cdd:PRK13900  12 LEPLKNIFAEDGVNEISINKPGEVWVEKKGDIRCEQIPELDLSHLKALGRLVAQATEQKISEEKPLLSATLPNGYRIQIV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 214 VPPIAVDGSLV-SIRKFKKDKLGIADLVRFGAFTE---------------------EMAAYLQAAVATRLNIIVSGGTGS 271
Cdd:PRK13900  92 FPPACEIGQIVySIRKPSGMQLTLDDYEKMGAFDEtateslvdeddvilnellaekKIKEFLEHAVISKKNIIISGGTST 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 272 GKTTTLNALSSFIDNSERILTIEDTAELQLqqahvgrmeSRPPNV---------EGKGAVTQRDCLRNALRMRPDRIIVG 342
Cdd:PRK13900 172 GKTTFTNAALREIPAIERLITVEDAREIVL---------SNHPNRvhllaskggQGRAKVTTQDLIEACLRLRPDRIIVG 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 343 ETRGEEVIDMLQAMNTGHDGSMTTIHANSARDGISRLENMVAMAGIEMPIKAVRAQIASAVNLIVQASRLQDGSRrmvSI 422
Cdd:PRK13900 243 ELRGAEAFSFLRAINTGHPGSISTLHADSPAMAIEQLKLMVMQAGLGMPPDQIKKYILNVVDIVVQLKRGSGGKR---YV 319


                 ...
gi 499656331 423 TEI 425
Cdd:PRK13900 320 SEI 322
ATPase_ComGA NF041000
competence type IV pilus ATPase ComGA;
272-412 2.21e-05

competence type IV pilus ATPase ComGA;


Pssm-ID: 468930 [Multi-domain]  Cd Length: 265  Bit Score: 45.90  E-value: 2.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 272 GKTTTLNALSSFIDNSERILTIEDTAE------LQLQqahvgrmesrppnVEGKGAVTQRDCLRNALRMRPDRIIVGETR 345
Cdd:NF041000 140 GKTTTMYSLARKLALNKQVITIEDPVEikepnfLQLQ-------------VNEKAGMTYDTLLKAALRHRPDILIIGEIR 206

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499656331 346 GEEVIDM-LQAMNTGHDgSMTTIHANSARDGISRLENMvamaGIEmpikavRAQIASAVNLIVqASRL 412
Cdd:NF041000 207 DAETAKAaIRAALTGHL-VLSTVHAKSAAGVIYRLLEL----GIS------KEELEQTLIGIS-YQRL 262
 
Name Accession Description Interval E-value
CpaF COG4962
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ...
 70-473 0e+00

Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443988 [Multi-domain]  Cd Length: 386  Bit Score: 551.31  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  70 ELKVELHRRllddlnlaaletASESSLRSEIAAICGEALEEMSVVLNKDERAILNQELYDEVMGLGPLEPLLKDETINDI 149
Cdd:COG4962    4 ELVERVRRR------------LDREELREEVRAAVAEALRAEGLVLSDAEREALARAVLDELFGLGPLEPLLDDPDVTDI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 150 LVNGPYRIFVERSGKLELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLADGSRFNAMVPPIAVDGSLVSIRKF 229
Cdd:COG4962   72 MVNGPDEVFVERGGRLERTDVRFDSEEELRRLIERIAARVGRRLDESSPIVDARLPDGSRVNAVIPPVARDGPSLSIRKF 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 230 KKDKLGIADLVRFGAFTEEMAAYLQAAVATRLNIIVsggtgsgktttLNALSSFIDNSERILTIEDTAELQLQQAHVGRM 309
Cdd:COG4962  152 RKRPLTLEDLVALGSLTPEMAEFLRAAVRARLNILVsggtgsgkttlLNALSGFIPPDERIVTIEDAAELQLQHPHVVRL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 310 ESRPPNVEGKGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDMLQAMNTGHDGSMTTIHANSARDGISRLENMVAMAGIE 389
Cdd:COG4962  232 ETRPPNVEGAGEVTLRDLVRNALRMRPDRIIVGEVRGAEALDMLQAMNTGHDGSMSTLHANSARDALARLETLALMAGEN 311

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 390 MPIKAVRAQIASAVNLIVQASRLQDGSRRMVSITEITGMEGDVISMQEIFRYERLGVEPSGKIIGRFnatgvrshySDRF 469
Cdd:COG4962  312 LPREAVRRQIASAIDLVVHLERLRDGRRRVTEIAEVTGMEGGRVVLQPIFRFDPGGLDAAGGVRPRF---------LERL 382


                 ....
gi 499656331 470 RQWG 473
Cdd:COG4962  383 EAAG 386
heli_sec_ATPase TIGR03819
helicase/secretion neighborhood ATPase; Members of this protein family comprise a distinct ...
 125-422 8.20e-100

helicase/secretion neighborhood ATPase; Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.


Pssm-ID: 200328  Cd Length: 340  Bit Score: 303.10  E-value: 8.20e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  125 QELYDEVMGLGPLEPLLKDETINDILVNGPYRIFVERSGKLELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARL 204
Cdd:TIGR03819  43 RALRRDLVGAGPLEPLLADPGVTDVLVNGPDEVWVDRGRGLERTDVRFPDEAAVRRLAQRLAAAAGRRLDDAQPWVDARL 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  205 ADGSRFNAMVPPIAVDGSLVSIRKFKKDKLGIADLVRFGAFTEEMAAYLQAAVATRLNIIVSGGTGSGKTTTLNALSSFI 284
Cdd:TIGR03819 123 PDGTRLHAVLPPVATDGTCLSLRVPRRRTFTLDELVAAGTIPPGVARLLRALVAARLAFLVSGGTGSGKTTLLSALLALV 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  285 DNSERILTIEDTAELQLQQAHVGRMESRPPNVEGKGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDMLQAMNTGHDGSM 364
Cdd:TIGR03819 203 PPDERIVLVEDAAELRPDHPHVVRLEARPANVEGAGAVTLTDLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHDGGA 282

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 499656331  365 TTIHANSARDGISRLENMVAMAGieMPIKAVRAQIASAVNLIVQASRLQDGSRRMVSI 422
Cdd:TIGR03819 283 GTLHANSPADVPARLEALGALAG--LDRAALHSQLAAALDVVLHVRRTPRGRRRVAEI 338
VirB11 COG0630
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell ...
 59-431 5.59e-74

Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell motility, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440395 [Multi-domain]  Cd Length: 462  Bit Score: 240.75  E-value: 5.59e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  59 DKEKKRKERLMELKVELHRRLLDDLNLAALETASESSLRSEIAAIcgEALEEMSVVLNKDERAILNQELYDEVMGLGPLE 138
Cdd:COG0630   88 VEEPPDSEEEEELLEEEERLLEELLLLEEEDALEDLEVLLLRELD--SLLKDYKIKVSEERLEKLLYYLLRDFVGYGKLD 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 139 PLLKDETINDILVNGP-YRIFVE--RSGKLElTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLADGSRFNAMVP 215
Cdd:COG0630  166 PLMRDPNIEDISCNGVgIPVYVYhrDYERIP-TNIVFESEEELDNFVVKLAQRSGKHISVARPIVDATLPDGSRIALTLG 244

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 216 P-IAVDGSLVSIRKFKKDKLGIADLVRFGAFTEEMAAYLQAAVATRLNIIVSGGTGSGKTTTLNALSSFIDNSERILTIE 294
Cdd:COG0630  245 PeVSRRGSSFTIRKFREVPLTPIDLIEWGTLSPELAAYLWLLLENGKSVLVAGGTASGKTTLLNALLSFIPPDAKIVTIE 324

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 295 DTAELQLQQAHVGRMESRPPNVEGKGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDMLQAMNTGHdGSMTTIHANSARD 374
Cdd:COG0630  325 DTRELNLPHENWISLVTRESFGGEEGDVTMFDLLKAALRQRPDYIVVGEVRGEEAYTLFQAMATGH-GVLSTFHADSVES 403

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 375 GISRLENmvamagieMPIKAVRAQIaSAVNLIVQASRLQDG---SRRMVSITEITGMEGD 431
Cdd:COG0630  404 AINRLTS--------PPINVPRTLL-QALDLVVFQKRVRVGgkrVRRVTSIVEIVGYDPE 454
VirB11-like_ATPase cd01130
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ...
 249-426 3.26e-72

Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.


Pssm-ID: 410874 [Multi-domain]  Cd Length: 177  Bit Score: 226.27  E-value: 3.26e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 249 MAAYLQAAVATRLNIIVSGGTGSGKTTTLNALSSFIDNSERILTIEDTAELQLQQAHVGRMESRPPNVEgKGAVTQRDCL 328
Cdd:cd01130    1 MAAFLRLAVRARKNILISGGTGSGKTTLLNALLSFIPPDERIVTIEDTRELQLPHPNVVHLLTRPGGGE-KGEVTMADLL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 329 RNALRMRPDRIIVGETRGEEVIDMLQAMNTGHDGSMTTIHANSARDGISRLENMVAMAGIEMPIKAVRAQIASAVNLIVQ 408
Cdd:cd01130   80 KAALRMRPDRIIVGEVRGGEAYDMLQAMNTGHPGSITTIHANSAEDAIDRLATLVLEAGVNLDEEALRRLIASAIDVIVH 159

                        170
                 ....*....|....*...
gi 499656331 409 ASRLQDGSRRMVSITEIT 426
Cdd:cd01130  160 VKRLGDGVRRVTEIYEVP 177
VirB11 TIGR02788
P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of ...
 141-425 1.65e-55

P-type DNA transfer ATPase VirB11; The VirB11 protein is found in the vir locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for DNA transfer. VirB11 is believed to be an ATPase. VirB11 is a homolog of the P-like conjugation system TrbB protein and the Flp pilus sytem protein TadA.


Pssm-ID: 274301  Cd Length: 308  Bit Score: 187.56  E-value: 1.65e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  141 LKDETINDILVNGPYRIFVERSGKLELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLADGSRFNAMVPPIAVD 220
Cdd:TIGR02788   2 LDDEDVTEICINRPGEVWVEGPGGWQRFDVPDLTFSHLMRLARAIASFSKQSISEENPILSATLPGGERVQIVIPPACEN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  221 GSLV-SIRKFKKDKLGIADLVRFGAFT-------------EEMAAYLQA---------AVATRLNIIVSGGTGSGKTTTL 277
Cdd:TIGR02788  82 DTVSiTIRKPSLVDFSLDDYEEKGFFDtvraqsgtlsdndEQLLELLDAgdikeflrlAIASRKNIIISGGTGSGKTTFL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  278 NALSSFIDNSERILTIEDTAELQLQQA-HVGRMESRppNVEGKGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDMLQAM 356
Cdd:TIGR02788 162 KSLVDEIPKDERIITIEDTREIFLPHPnYVHLFYSK--GGQGLAKVTPKDLLQSCLRMRPDRIILGELRGDEAFDFIRAV 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499656331  357 NTGHDGSMTTIHANSARDGISRLENMV--AMAGIEMPIKAVRAQIASAVNLIVQASRLQDGSRrmvsITEI 425
Cdd:TIGR02788 240 NTGHPGSITTLHAGSPEEAFEQLALMVksSQAGLGLDFAYIVKLVREVIDIVVQINRRGGGRK----ITEV 306
T2SSE pfam00437
Type II/IV secretion system protein; This family contains components of both the Type II ...
 133-398 9.22e-54

Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.


Pssm-ID: 425681 [Multi-domain]  Cd Length: 269  Bit Score: 181.71  E-value: 9.22e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  133 GLGPLEPLlkDETINDILVNGPYRIFV--ERSGKlELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLA----- 205
Cdd:pfam00437   1 NLIPLEAL--DEGASDIHVEPPERIVWirFRVDG-VLREIPFPDADALARLISRIKVMARLDISERRPPQDGRLPlrigg 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  206 DGSRFNAMVPPIAVDGSLVsIRKFKKD--KLGIADLVRFGAFTEEMAAYLQAAvatRLNIIVSGGTGSGKTTTLNALSSF 283
Cdd:pfam00437  78 KGVRVRVSTLPTAGGEKLV-IRLLDPSnvALSLDELGMTGAQDEALLEFLRQP---RGNILVTGPTGSGKTTTLYAALGE 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  284 IDNS-ERILTIEDTAELQLQQAHVGRMESRppnvegkGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDM-LQAMNTGHD 361
Cdd:pfam00437 154 LNTRdENIVTVEDPVEIQLEGINQVQLNAR-------AGVTFADLLRAILRQDPDRIMVGEIRDLETAEIaLQAANTGHL 226

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 499656331  362 GsMTTIHANSARDGISRLENM-VAMAGIEMPIKAVRAQ 398
Cdd:pfam00437 227 V-LSTLHTNSAAGALTRLQDMgVPPFELASSLLLVIAQ 263
TrbB_P TIGR02782
P-type conjugative transfer ATPase TrbB; The TrbB protein is found in the trb locus of ...
 140-427 3.53e-47

P-type conjugative transfer ATPase TrbB; The TrbB protein is found in the trb locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for plasmid conjugative transfer. TrbB is a homolog of the vir system VirB11 ATPase, and the Flp pilus sytem ATPase TadA. [Cellular processes, Conjugation]


Pssm-ID: 274297  Cd Length: 299  Bit Score: 165.30  E-value: 3.53e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  140 LLKDETINDILVNGPYRIFVERSGKlELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLA-DGSRFNAMVPPIa 218
Cdd:TIGR02782  13 ALDDPGVVEIMLNPDGRLWVERLGS-GMSPLGEMSPADAQRIIGLVADYLGTEVDRDKPIVEGELPlDGSRFEGLIPPV- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  219 VDGSLVSIRKFKKDKLGIADLVRFGAFTEEMAAYLQAAVATRLNIIVSGGTGSGKTTTLNALSSFI---DNSERILTIED 295
Cdd:TIGR02782  91 VAAPSFAIRKKAVAVFTLDDYVEAGIMTAAQRDVLREAVLARKNILVVGGTGSGKTTLANALLAEIaknDPTDRVVIIED 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331  296 TAELQLQQAHVGRMESRPpnvegkGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDMLQAMNTGHDGSMTTIHANSARDG 375
Cdd:TIGR02782 171 TRELQCAAPNVVQLRTSD------DAISMTRLLKATLRLRPDRIIVGEVRGGEALDLLKAWNTGHPGGIATIHANNAKAA 244

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 499656331  376 ISRLENMVAMAGIEmPIKAVraqIASAVNLIVQASRLQDGsRRMVSITEITG 427
Cdd:TIGR02782 245 LDRLEQLIQEVSVT-PMQTL---IAEAVDLVIFIARTPAG-RRVQEIAKVKG 291
PRK13900 PRK13900
type IV secretion system ATPase VirB11; Provisional
 134-425 6.52e-40

type IV secretion system ATPase VirB11; Provisional


Pssm-ID: 184381  Cd Length: 332  Bit Score: 146.83  E-value: 6.52e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 134 LGPLEPLLKDETINDILVNGPYRIFVERSGKLELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLADGSRFNAM 213
Cdd:PRK13900  12 LEPLKNIFAEDGVNEISINKPGEVWVEKKGDIRCEQIPELDLSHLKALGRLVAQATEQKISEEKPLLSATLPNGYRIQIV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 214 VPPIAVDGSLV-SIRKFKKDKLGIADLVRFGAFTE---------------------EMAAYLQAAVATRLNIIVSGGTGS 271
Cdd:PRK13900  92 FPPACEIGQIVySIRKPSGMQLTLDDYEKMGAFDEtateslvdeddvilnellaekKIKEFLEHAVISKKNIIISGGTST 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 272 GKTTTLNALSSFIDNSERILTIEDTAELQLqqahvgrmeSRPPNV---------EGKGAVTQRDCLRNALRMRPDRIIVG 342
Cdd:PRK13900 172 GKTTFTNAALREIPAIERLITVEDAREIVL---------SNHPNRvhllaskggQGRAKVTTQDLIEACLRLRPDRIIVG 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 343 ETRGEEVIDMLQAMNTGHDGSMTTIHANSARDGISRLENMVAMAGIEMPIKAVRAQIASAVNLIVQASRLQDGSRrmvSI 422
Cdd:PRK13900 243 ELRGAEAFSFLRAINTGHPGSISTLHADSPAMAIEQLKLMVMQAGLGMPPDQIKKYILNVVDIVVQLKRGSGGKR---YV 319


                 ...
gi 499656331 423 TEI 425
Cdd:PRK13900 320 SEI 322
PRK13894 PRK13894
conjugal transfer ATPase TrbB; Provisional
 134-427 1.35e-39

conjugal transfer ATPase TrbB; Provisional


Pssm-ID: 184377  Cd Length: 319  Bit Score: 145.65  E-value: 1.35e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 134 LGP-LEPLLKDETINDILVNGPYRIFVERSGKLELTDTTFKDERHLlRIIDKIVSAVGRRVDESTPYVDARLA-DGSRFN 211
Cdd:PRK13894  22 MGPeLLAALNDPKTVEIMLNADGKLWQERLGEPMRCIGTLRVAQAQ-AIIETIAGYHGKEVTRSKPILEGELPlDGSRFA 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 212 AMVPPIaVDGSLVSIRKFKKDKLGIADLVRFGAFTEEMAAYLQAAVATRLNIIVSGGTGSGKTTTLNALSS---FIDNSE 288
Cdd:PRK13894 101 GQLPPV-VPAPTFAIRKKAVAIFTLDQYVERGIMTAAQREAIIAAVRAHRNILVIGGTGSGKTTLVNAIINemvIQDPTE 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 289 RILTIEDTAELQLQ-----QAHVgrmesrppNVEgkgaVTQRDCLRNALRMRPDRIIVGETRGEEVIDMLQAMNTGHDGS 363
Cdd:PRK13894 180 RVFIIEDTGEIQCAaenyvQYHT--------SID----VNMTALLKTTLRMRPDRILVGEVRGPEALDLLMAWNTGHEGG 247

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499656331 364 MTTIHANSARDGISRLENMVAMAgiEMPIKAVRAQIASAVNLIVQASRlQDGSRRMVSITEITG 427
Cdd:PRK13894 248 AATLHANNAKAGLDRLKSLISMH--PDAPKPIEPLIGEAVHVVVHIAR-TPGGRRIQEILEVSG 308
PRK13833 PRK13833
conjugal transfer protein TrbB; Provisional
 141-430 7.31e-31

conjugal transfer protein TrbB; Provisional


Pssm-ID: 172360 [Multi-domain]  Cd Length: 323  Bit Score: 121.83  E-value: 7.31e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 141 LKDETINDILVNGPYRIFVERSGKlELTDTTFKDERHLLRIIDKIVSAVGRRVDESTPYVDARLA-DGSRFNAMVPPIaV 219
Cdd:PRK13833  26 LDDATVVEIMLNPDGKLFIERLGH-GVAPAGEMSAAAAEVVIGSVAHALQSEADDERPIISGELPiGGHRFEGLLPPV-V 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 220 DGSLVSIRKFKKDKLGIADLVRFGAFTEEMAAYLQAAVATRLNIIVSGGTGSGKTTTLNA-LSSFIDNS--ERILTIEDT 296
Cdd:PRK13833 104 SGPAFTIRRRASRLIPLDDYVTSKIMTEAQASVIRSAIDSRLNIVISGGTGSGKTTLANAvIAEIVASApeDRLVILEDT 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 297 AELQLQQAHVGRMESrppnvegKGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDMLQAMNTGHDGSMTTIHANSARDGI 376
Cdd:PRK13833 184 AEIQCAAENAVALHT-------SDTVDMARLLKSTMRLRPDRIIVGEVRDGAALTLLKAWNTGHPGGVTTIHSNTAMSAL 256

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 499656331 377 SRLENMVAMAGiEMPIKAVraqIASAVNLIVQASRLQDGsRRMVSITEITGMEG 430
Cdd:PRK13833 257 RRLEQLTAEAS-QQPMQEV---IGEAVDLIVSIERTGKG-RRVREVIHVEGFAN 305
PRK13851 PRK13851
type IV secretion system protein VirB11; Provisional
 134-407 7.34e-22

type IV secretion system protein VirB11; Provisional


Pssm-ID: 172375  Cd Length: 344  Bit Score: 96.51  E-value: 7.34e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 134 LGPLEPLLKDETINDILVNGPYRIFVERSGKLELTDTTFkdERHLLRIIDKIVSAVGRR-VDESTPYVDARLADGSRFNA 212
Cdd:PRK13851  11 LKPVLEWLDDPRTEEVAINRPGEAFVRQAGVFTKFPLPL--SYDDLEDIAILAGALRKQdVGPRNPLCATELPGGERLQI 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 213 MVPPIAVDGSL-VSIR------------------------KFKKDKLGIADLVRFGAFTE-EMAAYLQAAVATRLNIIVS 266
Cdd:PRK13851  89 CLPPTVPSGTVsLTIRrpssrvselkevssrydasrwnqwQERRKRRDQLDEAILRHYDNgDLEAFLHACVVGRLTMLLC 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 267 GGTGSGKTTTLNALSSFIDNSERILTIEDTAELQL-QQAHVGRMESRppNVEGKGAVTQRDCLRNALRMRPDRIIVGETR 345
Cdd:PRK13851 169 GPTGSGKTTMSKTLISAIPPQERLITIEDTLELVIpHENHVRLLYSK--NGAGLGAVTAEHLLQASLRMRPDRILLGEMR 246

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499656331 346 GEEVIDMLQAMNTGHDGSMTTIHANSARDGISRLENMV--AMAGIEMPIKAVRAQIASAVNLIV 407
Cdd:PRK13851 247 DDAAWAYLSEVVSGHPGSISTIHGANPVQGFKKLFSLVksSAQGASLEDRTLIDMLATAIDVIV 310
type_II_IV_secretion_ATPases cd19477
type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP ...
 262-381 1.06e-19

type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410885 [Multi-domain]  Cd Length: 168  Bit Score: 86.29  E-value: 1.06e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 262 NIIVSGGTGSGKTTTLNALSSFIDNSERILTIEDTAELQLQQA-HVGRMESRPpnvegkgAVTQRDCLRNALRMRPDRII 340
Cdd:cd19477   12 NVIVCGGTGSGKTTYIKSILEFIPKEERIISIEDTEEIVFKHHkNYTQLFFGG-------NITSADCLKSCLRQRPDRII 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 499656331 341 VGETRGEEVIDMLQAMNTGHDGSMTTIHANSARDGISRLEN 381
Cdd:cd19477   85 LGELRSSEAYDFYNVLCSGHKGTLTTLHAGSSEEAFIRLAN 125
PulE-GspE-like cd01129
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ...
 273-412 2.07e-12

PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.


Pssm-ID: 410873 [Multi-domain]  Cd Length: 159  Bit Score: 64.81  E-value: 2.07e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 273 KTTTLNALSSFIDNSER-ILTIEDTAELQLQQAhvgrMESrppNVEGKGAVTQRDCLRNALRMRPDRIIVGETRGEEVID 351
Cdd:cd01129   24 KTTTLYAMLRELNGPERnIITIEDPVEYQIPGI----NQS---QVNEKIGLTFADALRAILRQDPDIIMVGEIRDAETAE 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 499656331 352 M-LQAMNTGHdgsM--TTIHANSARDGISRLENMvamaGIEmpikavRAQIASAVNLIVqASRL 412
Cdd:cd01129   97 IaIRAALTGH---LvlSTLHTNDALGAITRLLDM----GIE------PFLLASALRGVI-AQRL 146
PilT cd01131
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein ...
 280-425 1.55e-10

Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility.


Pssm-ID: 410875 [Multi-domain]  Cd Length: 223  Bit Score: 61.01  E-value: 1.55e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 280 LSSFID--NSER---ILTIEDTAELqlqqahvgRMESRppnvegKGAVTQR----------DCLRNALRMRPDRIIVGET 344
Cdd:cd01131   38 LAAMIDyiNETRskhIITIEDPIEF--------VHKHK------KSLINQRevgrdtesfaAALRAALREDPDVILVGEM 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 345 RGEEVIDM-LQAMNTGHDgSMTTIHANSARDGISRLENMVAMAGIEMpikaVRAQIASAVNLIVqASRL---QDGSRRmV 420
Cdd:cd01131  104 RDLETIELaLTAAETGHL-VFSTLHTNSAAQTIDRIIDVFPPEQQEQ----VRIQLASSLRGVI-SQRLlpkKDGGGR-V 176


                 ....*
gi 499656331 421 SITEI 425
Cdd:cd01131  177 AAFEI 181
PulE COG2804
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ...
 282-412 4.16e-09

Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442055 [Multi-domain]  Cd Length: 561  Bit Score: 58.67  E-value: 4.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 282 SFIDNSER-ILTIEDTAELQLqqAHVGRMESRPpnvegKGAVTQRDCLRNALRMRPDRIIVGETRGEEVIDM-LQAMNTG 359
Cdd:COG2804  335 NELNTPERnIITVEDPVEYQL--PGINQVQVNP-----KIGLTFASALRSILRQDPDVIMVGEIRDLETAEIaVQAALTG 407

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 499656331 360 HdGSMTTIHANSARDGISRLENMvamaGIEmpikavRAQIASAVNLIVqASRL 412
Cdd:COG2804  408 H-LVLSTLHTNDAPSAITRLLDM----GVE------PFLLASSLLGVL-AQRL 448
DotB_TraJ cd19516
dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of ...
 328-383 2.85e-07

dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of the type IVb secretion (T4bS) system, also known as the dot/icm system, and is the main energy supplier of the secretion system. It is an ATPase, similar to the VirB11 component of the T4aS systems. This family also includes Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ encoded on the tra (transfer) operon.


Pssm-ID: 410924 [Multi-domain]  Cd Length: 179  Bit Score: 50.45  E-value: 2.85e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 499656331 328 LRNALRMRPDRIIVGETRGEEVID-MLQAMNTGHDgSMTTIHANSARDGISRLENMV 383
Cdd:cd19516   82 VREALRRKPSLIGVGELRDQETISaAVEASLTGHP-VYSTVHTKSVAETIRRLISLF 137
PilT COG2805
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular ...
 273-425 6.30e-06

Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular structures];


Pssm-ID: 442056  Cd Length: 342  Bit Score: 48.16  E-value: 6.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 273 KTTTLNALssfID--NSER---ILTIEDTAELQLQQahvgrmesrppnveGKGAVTQR----DC------LRNALRMRPD 337
Cdd:COG2805  138 KSTTLAAM---IDyiNETRakhIITIEDPIEFVHKH--------------KKSLINQRevgrDTpsfanaLRAALREDPD 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 338 RIIVGETRGEEVIDM-LQAMNTGHdgsMTTIHANSARDGISRLENMVamagiemPI---KAVRAQIASAVNLIVqASRL- 412
Cdd:COG2805  201 VILVGEMRDLETIEAaLTAAETGHl-vFATLHTNSAAQTIDRIIDVF-------PPeeqAQIRSQLAESLRGVI-SQRLl 271

                        170
                 ....*....|....*
gi 499656331 413 --QDGSRRmVSITEI 425
Cdd:COG2805  272 prADGGGR-VAAREI 285
ATPase_ComGA NF041000
competence type IV pilus ATPase ComGA;
272-412 2.21e-05

competence type IV pilus ATPase ComGA;


Pssm-ID: 468930 [Multi-domain]  Cd Length: 265  Bit Score: 45.90  E-value: 2.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 272 GKTTTLNALSSFIDNSERILTIEDTAE------LQLQqahvgrmesrppnVEGKGAVTQRDCLRNALRMRPDRIIVGETR 345
Cdd:NF041000 140 GKTTTMYSLARKLALNKQVITIEDPVEikepnfLQLQ-------------VNEKAGMTYDTLLKAALRHRPDILIIGEIR 206

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499656331 346 GEEVIDM-LQAMNTGHDgSMTTIHANSARDGISRLENMvamaGIEmpikavRAQIASAVNLIVqASRL 412
Cdd:NF041000 207 DAETAKAaIRAALTGHL-VLSTVHAKSAAGVIYRLLEL----GIS------KEELEQTLIGIS-YQRL 262
PRK10436 PRK10436
hypothetical protein; Provisional
 273-412 9.59e-05

hypothetical protein; Provisional


Pssm-ID: 236694  Cd Length: 462  Bit Score: 44.92  E-value: 9.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499656331 273 KTTTL-NALSSFIDNSERILTIEDTAELQLQ-----QAHvgrmesrppnveGKGAVTQRDCLRNALRMRPDRIIVGETRG 346
Cdd:PRK10436 231 KTVTLySALQTLNTAQINICSVEDPVEIPLAginqtQIH------------PKAGLTFQRVLRALLRQDPDVIMVGEIRD 298

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499656331 347 EEVIDM-LQAMNTGHDgSMTTIHANSARDGISRLENMvamaGIEmpikavRAQIASAVNLIVqASRL 412
Cdd:PRK10436 299 GETAEIaIKAAQTGHL-VLSTLHTNSTSETLVRLQQM----GIA------RWMLASALKLVI-AQRL 353
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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