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Conserved domains on  [gi|499667361|ref|WP_011348095|]
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aldehyde dehydrogenase iron-sulfur subunit PaoA [Xanthomonas euvesicatoria]

Protein Classification

PRK11433 family protein( domain architecture ID 11485345)

PRK11433 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK11433 PRK11433
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
 1-216 1.51e-138

aldehyde oxidoreductase 2Fe-2S subunit; Provisional


:

Pssm-ID: 236910 [Multi-domain]  Cd Length: 217  Bit Score: 386.44  E-value: 1.51e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361   1 MRDIKMTRREVLIAGTASAASVAATQSMAATAAtaisqRPATEPANASSQVAFEVNGKPVTLTLDNRTTLLDALREHLHL 80
Cdd:PRK11433   7 PHDLSLTRRDLLKVSAATAATAAAYPHSTLAAS-----VPAATPAPEISPVTLKVNGKTEQLEVDTRTTLLDALREHLHL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  81 TGTKKGCDHGQCGACTVIVDGQRMNACLSLAVMHEGAKVTTIEGLGRPDKLHPMQAAFVKHDGYQCGYCTPGQICSAVAV 160
Cdd:PRK11433  82 TGTKKGCDHGQCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFVKHDGFQCGYCTPGQICSSVAV 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 499667361 161 LDEVKRGIPSHVTEDLTGKTKLTTPELQERMSGNICRCGAYSNIVEAINDVAGGRA 216
Cdd:PRK11433 162 LKEIKDGIPSHVTVDLTAAPELTADEIRERMSGNICRCGAYSNILEAIEDVAGEIA 217
 
Name Accession Description Interval E-value
PRK11433 PRK11433
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
 1-216 1.51e-138

aldehyde oxidoreductase 2Fe-2S subunit; Provisional


Pssm-ID: 236910 [Multi-domain]  Cd Length: 217  Bit Score: 386.44  E-value: 1.51e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361   1 MRDIKMTRREVLIAGTASAASVAATQSMAATAAtaisqRPATEPANASSQVAFEVNGKPVTLTLDNRTTLLDALREHLHL 80
Cdd:PRK11433   7 PHDLSLTRRDLLKVSAATAATAAAYPHSTLAAS-----VPAATPAPEISPVTLKVNGKTEQLEVDTRTTLLDALREHLHL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  81 TGTKKGCDHGQCGACTVIVDGQRMNACLSLAVMHEGAKVTTIEGLGRPDKLHPMQAAFVKHDGYQCGYCTPGQICSAVAV 160
Cdd:PRK11433  82 TGTKKGCDHGQCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFVKHDGFQCGYCTPGQICSSVAV 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 499667361 161 LDEVKRGIPSHVTEDLTGKTKLTTPELQERMSGNICRCGAYSNIVEAINDVAGGRA 216
Cdd:PRK11433 162 LKEIKDGIPSHVTVDLTAAPELTADEIRERMSGNICRCGAYSNILEAIEDVAGEIA 217
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 50-216 3.36e-86

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 251.55  E-value: 3.36e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  50 QVAFEVNGKPVTLTLDNRTTLLDALREHLHLTGTKKGCDHGQCGACTVIVDGQRMNACLSLAVMHEGAKVTTIEGLGRPD 129
Cdd:COG2080    3 MITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAEDG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361 130 KLHPMQAAFVKHDGYQCGYCTPGQICSAVAVLDEVKRGipshvTEDltgktklttpELQERMSGNICRCGAYSNIVEAIN 209
Cdd:COG2080   83 ELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNP-----TEE----------EIREALSGNLCRCTGYVRIVRAVK 147


                 ....*..
gi 499667361 210 DVAGGRA 216
Cdd:COG2080  148 RAAAALR 154
glyceraldDH_gamma NF041020
glyceraldehyde dehydrogenase subunit gamma;
50-212 7.34e-45

glyceraldehyde dehydrogenase subunit gamma;


Pssm-ID: 468949 [Multi-domain]  Cd Length: 162  Bit Score: 146.86  E-value: 7.34e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  50 QVAFEVNGKPVTLTLDNRTTLLDALREHLHLTGTKKGCDHGQCGACTVIVDGQRMNACLSLAVMHEGAKVTTIEGLGRPD 129
Cdd:NF041020  10 KIRVKVNGVWYEAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGKSVKSCTVLAVQADGAEITTIEGLSKDG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361 130 KLHPMQAAFVKHDGYQCGYCTPGQICSAVAVLDEvkrgipshvtedltgKTKLTTPELQERMSGNICRCGAYSNIVEAIN 209
Cdd:NF041020  90 KLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKE---------------NPNPTEEEIRDGIHGNLCRCTGYQNIVKAVK 154


                 ...
gi 499667361 210 DVA 212
Cdd:NF041020 155 EAS 157
xanthine_xdhA TIGR02963
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit ...
 53-207 5.50e-39

xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit (or, in eukaryotes, the N-terminal domain) of xanthine dehydrogenase, an enzyme of purine catabolism via urate. The small subunit contains both an FAD and a 2Fe-2S cofactor. Aldehyde oxidase (retinal oxidase) appears to have arisen as a neofunctionalization among xanthine dehydrogenases in eukaryotes and [Purines, pyrimidines, nucleosides, and nucleotides, Other]


Pssm-ID: 274365 [Multi-domain]  Cd Length: 467  Bit Score: 139.33  E-value: 5.50e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361   53 FEVNGKPVTLT-LDNRTTLLDALREHLHLTGTKKGCDHGQCGACTVIV----DGQRM-----NACLS-LAVMHeGAKVTT 121
Cdd:TIGR02963   3 FFLNGETVTLSdVDPTRTLLDYLREDAGLTGTKEGCAEGDCGACTVVVgelvDGGKLryrsvNACIQfLPSLD-GKAVVT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  122 IEGLGRPDK-LHPMQAAFVKHDGYQCGYCTPGQICSAVAVLDevkrgipSHVTEDLTgktklttpELQERMSGNICRCGA 200
Cdd:TIGR02963  82 VEDLRQPDGrLHPVQQAMVECHGSQCGFCTPGFVMSLYALYK-------NSPAPSRA--------DIEDALQGNLCRCTG 146


                  ....*..
gi 499667361  201 YSNIVEA 207
Cdd:TIGR02963 147 YRPILDA 153
Fer2_2 pfam01799
[2Fe-2S] binding domain;
121-208 1.86e-31

[2Fe-2S] binding domain;


Pssm-ID: 460336 [Multi-domain]  Cd Length: 73  Bit Score: 109.44  E-value: 1.86e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  121 TIEGLGRPDKlHPMQAAFVKHDGYQCGYCTPGQICSAVAVLDEvkrgIPSHVTEDltgktklttpELQERMSGNICRCGA 200
Cdd:pfam01799   1 TIEGLAESGG-EPVQQAFAEAGAVQCGYCTPGMIMSAYALLER----NPPPPTEA----------EIREALSGNLCRCTG 65


                  ....*...
gi 499667361  201 YSNIVEAI 208
Cdd:pfam01799  66 YRRIVDAV 73
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 51-100 8.42e-08

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 48.16  E-value: 8.42e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 499667361  51 VAFEVNGKPVTLTLDNRTTLLDALREHLHltGTKKGCDHGQCGACTVIVD 100
Cdd:cd00207    1 VTINVPGSGVEVEVPEGETLLDAAREAGI--DIPYSCRAGACGTCKVEVV 48
 
Name Accession Description Interval E-value
PRK11433 PRK11433
aldehyde oxidoreductase 2Fe-2S subunit; Provisional
 1-216 1.51e-138

aldehyde oxidoreductase 2Fe-2S subunit; Provisional


Pssm-ID: 236910 [Multi-domain]  Cd Length: 217  Bit Score: 386.44  E-value: 1.51e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361   1 MRDIKMTRREVLIAGTASAASVAATQSMAATAAtaisqRPATEPANASSQVAFEVNGKPVTLTLDNRTTLLDALREHLHL 80
Cdd:PRK11433   7 PHDLSLTRRDLLKVSAATAATAAAYPHSTLAAS-----VPAATPAPEISPVTLKVNGKTEQLEVDTRTTLLDALREHLHL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  81 TGTKKGCDHGQCGACTVIVDGQRMNACLSLAVMHEGAKVTTIEGLGRPDKLHPMQAAFVKHDGYQCGYCTPGQICSAVAV 160
Cdd:PRK11433  82 TGTKKGCDHGQCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFVKHDGFQCGYCTPGQICSSVAV 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 499667361 161 LDEVKRGIPSHVTEDLTGKTKLTTPELQERMSGNICRCGAYSNIVEAINDVAGGRA 216
Cdd:PRK11433 162 LKEIKDGIPSHVTVDLTAAPELTADEIRERMSGNICRCGAYSNILEAIEDVAGEIA 217
CutS COG2080
Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and ...
 50-216 3.36e-86

Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family [Energy production and conversion]; Aldehyde, CO, or xanthine dehydrogenase, Fe-S subunit, CoxS/CutS family is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441683 [Multi-domain]  Cd Length: 155  Bit Score: 251.55  E-value: 3.36e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  50 QVAFEVNGKPVTLTLDNRTTLLDALREHLHLTGTKKGCDHGQCGACTVIVDGQRMNACLSLAVMHEGAKVTTIEGLGRPD 129
Cdd:COG2080    3 MITLTVNGKPVEVDVDPDTPLLDVLRDDLGLTGTKFGCGHGQCGACTVLVDGKAVRSCLTLAVQADGKEITTIEGLAEDG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361 130 KLHPMQAAFVKHDGYQCGYCTPGQICSAVAVLDEVKRGipshvTEDltgktklttpELQERMSGNICRCGAYSNIVEAIN 209
Cdd:COG2080   83 ELHPLQQAFIEHGALQCGYCTPGMIMAAVALLDENPNP-----TEE----------EIREALSGNLCRCTGYVRIVRAVK 147


                 ....*..
gi 499667361 210 DVAGGRA 216
Cdd:COG2080  148 RAAAALR 154
glyceraldDH_gamma NF041020
glyceraldehyde dehydrogenase subunit gamma;
50-212 7.34e-45

glyceraldehyde dehydrogenase subunit gamma;


Pssm-ID: 468949 [Multi-domain]  Cd Length: 162  Bit Score: 146.86  E-value: 7.34e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  50 QVAFEVNGKPVTLTLDNRTTLLDALREHLHLTGTKKGCDHGQCGACTVIVDGQRMNACLSLAVMHEGAKVTTIEGLGRPD 129
Cdd:NF041020  10 KIRVKVNGVWYEAEVEPRKLLVHFLRDDLGFTGTHVGCDTSTCGACTVIMNGKSVKSCTVLAVQADGAEITTIEGLSKDG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361 130 KLHPMQAAFVKHDGYQCGYCTPGQICSAVAVLDEvkrgipshvtedltgKTKLTTPELQERMSGNICRCGAYSNIVEAIN 209
Cdd:NF041020  90 KLHPIQEAFWENHALQCGYCTPGMIMQAYFLLKE---------------NPNPTEEEIRDGIHGNLCRCTGYQNIVKAVK 154


                 ...
gi 499667361 210 DVA 212
Cdd:NF041020 155 EAS 157
XdhA COG4630
Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and ...
 53-207 1.31e-42

Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA [Nucleotide transport and metabolism];


Pssm-ID: 443668 [Multi-domain]  Cd Length: 476  Bit Score: 149.13  E-value: 1.31e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  53 FEVNGKPVTLT-LDNRTTLLDALREHLHLTGTKKGCDHGQCGACTVIV----DGQR----MNACLSLAVMHEGAKVTTIE 123
Cdd:COG4630    3 FLLNGELVELSdVPPTTTLLDWLREDRGLTGTKEGCAEGDCGACTVVVgeldDGGLryraVNACILFLPQLDGKALVTVE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361 124 GLGRPD-KLHPMQAAFVKHDGYQCGYCTPGQICSAVAvldEVKRGipshvtedltgkTKLTTPELQERMSGNICRCGAYS 202
Cdd:COG4630   83 GLAGPDgALHPVQQAMVDHHGSQCGFCTPGFVMSLFA---LYERG------------PAPDRADIEDALSGNLCRCTGYR 147


                 ....*
gi 499667361 203 NIVEA 207
Cdd:COG4630  148 PIIDA 152
xanthine_xdhA TIGR02963
xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit ...
 53-207 5.50e-39

xanthine dehydrogenase, small subunit; Members of this protein family are the small subunit (or, in eukaryotes, the N-terminal domain) of xanthine dehydrogenase, an enzyme of purine catabolism via urate. The small subunit contains both an FAD and a 2Fe-2S cofactor. Aldehyde oxidase (retinal oxidase) appears to have arisen as a neofunctionalization among xanthine dehydrogenases in eukaryotes and [Purines, pyrimidines, nucleosides, and nucleotides, Other]


Pssm-ID: 274365 [Multi-domain]  Cd Length: 467  Bit Score: 139.33  E-value: 5.50e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361   53 FEVNGKPVTLT-LDNRTTLLDALREHLHLTGTKKGCDHGQCGACTVIV----DGQRM-----NACLS-LAVMHeGAKVTT 121
Cdd:TIGR02963   3 FFLNGETVTLSdVDPTRTLLDYLREDAGLTGTKEGCAEGDCGACTVVVgelvDGGKLryrsvNACIQfLPSLD-GKAVVT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  122 IEGLGRPDK-LHPMQAAFVKHDGYQCGYCTPGQICSAVAVLDevkrgipSHVTEDLTgktklttpELQERMSGNICRCGA 200
Cdd:TIGR02963  82 VEDLRQPDGrLHPVQQAMVECHGSQCGFCTPGFVMSLYALYK-------NSPAPSRA--------DIEDALQGNLCRCTG 146


                  ....*..
gi 499667361  201 YSNIVEA 207
Cdd:TIGR02963 147 YRPILDA 153
PRK09908 PRK09908
xanthine dehydrogenase iron sulfur-binding subunit XdhC;
54-210 1.39e-37

xanthine dehydrogenase iron sulfur-binding subunit XdhC;


Pssm-ID: 182139 [Multi-domain]  Cd Length: 159  Bit Score: 128.11  E-value: 1.39e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  54 EVNGKPVTLTLDNRTTLLDALREHlHLTGTKKGCDHGQCGACTVIVDGQRMNACLSLAVMHEGAKVTTIEGLGRPDKLHP 133
Cdd:PRK09908  12 TINGMPFQLHAAPGTPLSELLREQ-GLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEAKGGKLSH 90

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499667361 134 MQAAFVKHDGYQCGYCTPGQICSAVAVLDEVKRgipshvtedltgkTKLTTPELQERMSGNICRCGAYSNIVEAIND 210
Cdd:PRK09908  91 VQQAYAKSGAVQCGFCTPGLIMATTAMLAKPRE-------------KPLTITEIRRGLAGNLCRCTGYQMIVNTVLD 154
pucE TIGR03198
xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the ...
 50-214 3.56e-37

xanthine dehydrogenase E subunit; This gene has been characterized in B. subtilis as the Iron-sulfur cluster binding-subunit of xanthine dehydrogenase (pucE), acting in conjunction with pucC, the FAD-binding subunit and pucD, the molybdopterin binding subunit. The more common XDH complex (GenProp0640) includes the xdhA gene as the Fe-S cluster binding component.


Pssm-ID: 132242 [Multi-domain]  Cd Length: 151  Bit Score: 126.89  E-value: 3.56e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361   50 QVAFEVNGKPVTLTLDNRTTLLDALREHLHLTGTKKGCDHGQCGACTVIVDGQRMNACLSLAVMHEGAKVTTIEGLGRpD 129
Cdd:TIGR03198   3 QFRFTVNGQAWEVAAVPTTRLSDLLRKELQLTGTKVSCGIGRCGACSVLIDGKLANACLTMAYQADGHEITTIEGIAE-N 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  130 KLHPMQAAFVKHDGYQCGYCTPGQICSAVAVLDEVKrgipshvtedltgktKLTTPELQERMSGNICRCGAYSNIVEAIN 209
Cdd:TIGR03198  82 ELDPCQTAFLEEGGFQCGYCTPGMVVALKALFRETP---------------QPSDEDMEEGLSGNLCRCTGYGGIIRSAC 146


                  ....*
gi 499667361  210 DVAGG 214
Cdd:TIGR03198 147 RIRRG 151
Fer2_2 pfam01799
[2Fe-2S] binding domain;
121-208 1.86e-31

[2Fe-2S] binding domain;


Pssm-ID: 460336 [Multi-domain]  Cd Length: 73  Bit Score: 109.44  E-value: 1.86e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  121 TIEGLGRPDKlHPMQAAFVKHDGYQCGYCTPGQICSAVAVLDEvkrgIPSHVTEDltgktklttpELQERMSGNICRCGA 200
Cdd:pfam01799   1 TIEGLAESGG-EPVQQAFAEAGAVQCGYCTPGMIMSAYALLER----NPPPPTEA----------EIREALSGNLCRCTG 65


                  ....*...
gi 499667361  201 YSNIVEAI 208
Cdd:pfam01799  66 YRRIVDAV 73
PLN02906 PLN02906
xanthine dehydrogenase
 69-207 3.54e-31

xanthine dehydrogenase


Pssm-ID: 215491 [Multi-domain]  Cd Length: 1319  Bit Score: 120.19  E-value: 3.54e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361   69 TLLDALREhLHLTGTKKGCDHGQCGACTVIVDG----------QRMNACLSLAVMHEGAKVTTIEGLG-RPDKLHPMQAA 137
Cdd:PLN02906    3 TLLEYLRD-LGLTGTKLGCGEGGCGACTVMVSHydrktgkcvhYAVNACLAPLYSVEGMHVITVEGIGnRRDGLHPVQEA 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  138 FVKHDGYQCGYCTPGQICSAVAVLDevkrgipshvtedlTGKTKLTTPELQERMSGNICRCGAYSNIVEA 207
Cdd:PLN02906   82 LASMHGSQCGFCTPGFIMSMYALLR--------------SSKTPPTEEQIEECLAGNLCRCTGYRPILDA 137
mam_aldehyde_ox TIGR02969
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
 49-207 2.42e-30

aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.


Pssm-ID: 132014 [Multi-domain]  Cd Length: 1330  Bit Score: 117.80  E-value: 2.42e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361    49 SQVAFEVNG-KPVTLTLDNRTTLLDALREHLHLTGTKKGCDHGQCGACTVIVDGQR----------MNACLSLAVMHEGA 117
Cdd:TIGR02969    1 PELLFYVNGrKVVEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCGACTVMISRYNpstksirhhpVNACLTPICSLYGA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361   118 KVTTIEGLGRP-DKLHPMQAAFVKHDGYQCGYCTPGQICSAVAVLdevkRGIPSHVTEDLTgktklttpelqERMSGNIC 196
Cdd:TIGR02969   81 AVTTVEGIGSTrTRLHPVQERIAKCHGTQCGFCTPGMVMSMYALL----RNHPEPTLDQLT-----------DALGGNLC 145

                          170
                   ....*....|.
gi 499667361   197 RCGAYSNIVEA 207
Cdd:TIGR02969  146 RCTGYRPIIDA 156
PLN00192 PLN00192
aldehyde oxidase
 47-207 3.11e-28

aldehyde oxidase


Pssm-ID: 215096 [Multi-domain]  Cd Length: 1344  Bit Score: 111.73  E-value: 3.11e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361   47 ASSQVAFEVNGKPVTL-TLDNRTTLLDALREHLHLTGTKKGCDHGQCGACTVI----------VDGQRMNACLSLAVMHE 115
Cdd:PLN00192    2 SNMSLVFAVNGERFELsSVDPSTTLLEFLRTQTPFKSVKLGCGEGGCGACVVLlskydpvldqVEDFTVSSCLTLLCSVN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  116 GAKVTTIEGLGRP-DKLHPMQAAFVKHDGYQCGYCTPG---QICSAVAVLDEVKRGIPShvtedlTGKTKLTTPELQERM 191
Cdd:PLN00192   82 GCSITTSEGLGNSkDGFHPIHKRFAGFHASQCGFCTPGmciSLFSALVNADKTDRPEPP------SGFSKLTVVEAEKAV 155

                         170
                  ....*....|....*.
gi 499667361  192 SGNICRCGAYSNIVEA 207
Cdd:PLN00192  156 SGNLCRCTGYRPIVDA 171
PRK09800 PRK09800
putative hypoxanthine oxidase; Provisional
 51-208 1.31e-08

putative hypoxanthine oxidase; Provisional


Pssm-ID: 182084 [Multi-domain]  Cd Length: 956  Bit Score: 54.45  E-value: 1.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361  51 VAFEVNGKPVTLTL---DNRTTLLDALREHlhltgTKKGCDHGQ--CGACTVIVDGQRMNACLSLAVMHEGAKVTTIEGL 125
Cdd:PRK09800   3 IHFTLNGAPQELTVnpgENVQKLLFNMGMH-----SVRNSDDGFgfAGSDAIIFNGNIVNASLLIAAQLEKADIRTAESL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361 126 GRPDKLHPMQAAFVKHDGYQCGYCTPgqicsAVAVLdevkrgipshVTEDLTGKTKLTTPELQERMSGNICRCGAYSNIV 205
Cdd:PRK09800  78 GKWNELSLVQQAMVDVGVVQSGYNDP-----AAALI----------ITDLLDRIAAPTREEIDDALSGLFSRDAGWQQYY 142


                 ...
gi 499667361 206 EAI 208
Cdd:PRK09800 143 QVI 145
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 51-100 8.42e-08

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 48.16  E-value: 8.42e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 499667361  51 VAFEVNGKPVTLTLDNRTTLLDALREHLHltGTKKGCDHGQCGACTVIVD 100
Cdd:cd00207    1 VTINVPGSGVEVEVPEGETLLDAAREAGI--DIPYSCRAGACGTCKVEVV 48
Fer2 pfam00111
2Fe-2S iron-sulfur cluster binding domain;
53-111 1.38e-06

2Fe-2S iron-sulfur cluster binding domain;


Pssm-ID: 395061 [Multi-domain]  Cd Length: 77  Bit Score: 44.82  E-value: 1.38e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499667361   53 FEVNGKPVTLTL-DNRTTLLDALREHLhlTGTKKGCDHGQCGACTVIV------------------DGQRMNACLSLA 111
Cdd:pfam00111   1 VTINGKGVTIEVpDGETTLLDAAEEAG--IDIPYSCRGGGCGTCAVKVlegedqsdqsfleddelaAGYVVLACQTYP 76
PRK12576 PRK12576
succinate dehydrogenase/fumarate reductase iron-sulfur subunit;
62-126 1.81e-03

succinate dehydrogenase/fumarate reductase iron-sulfur subunit;


Pssm-ID: 237143 [Multi-domain]  Cd Length: 279  Bit Score: 38.58  E-value: 1.81e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499667361  62 LTLDNRTTLLDALR----EHLHLTGTKKGCDHGQCGACTVIVDGQRMNACLSLA--VMHEGAKVTTIEGLG 126
Cdd:PRK12576  29 VKVDRFTQVTEALRrikeEQDPTLSYRASCHMAVCGSCGMKINGEPRLACKTLVldVAKKYNSVITIEPMD 99
Fer2_3 pfam13085
2Fe-2S iron-sulfur cluster binding domain; The 2Fe-2S ferredoxin family have a general core ...
 60-142 2.27e-03

2Fe-2S iron-sulfur cluster binding domain; The 2Fe-2S ferredoxin family have a general core structure consisting of beta(2)-alpha-beta(2) which abeta-grasp type fold. The domain is around one hundred amino acids with four conserved cysteine residues to which the 2Fe-2S cluster is ligated.


Pssm-ID: 432963 [Multi-domain]  Cd Length: 107  Bit Score: 36.45  E-value: 2.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499667361   60 VTLTLDNRTTLLDALRE-HLHLTGT---KKGCDHGQCGACTVIVDGQRMNAClslavmhegaKVTTIEGLGRPDKLHPMQ 135
Cdd:pfam13085  21 YEVPYEEGMTVLDALNKiKEEQDPTlafRRSCREGICGSCAMNINGKPRLAC----------KTLIDDLLGQDITLEPLP 90


                  ....*..
gi 499667361  136 AAFVKHD 142
Cdd:pfam13085  91 GFPVIRD 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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