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Conserved domains on  [gi|499672172|ref|WP_011352906|]
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MULTISPECIES: cell division protein ZapA [Burkholderia]

Protein Classification

cell division protein ZapA( domain architecture ID 10006860)

cell division protein ZapA interacts with FtsZ, a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the cell cycle

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZapA COG3027
Cell division protein ZapA, inhibits GTPase activity of FtsZ [Cell cycle control, cell ...
 1-102 1.14e-23

Cell division protein ZapA, inhibits GTPase activity of FtsZ [Cell cycle control, cell division, chromosome partitioning];


:

Pssm-ID: 442263 [Multi-domain]  Cd Length: 94  Bit Score: 86.47  E-value: 1.14e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499672172   1 MSTKQIEVSILGQAYRLACSAETEAALLEAVARVDAEMSKIRSNSSVRGTDRIAVMAALSLASELLRLQTSVrhgeafpa 80
Cdd:COG3027    1 MSMNRVTVTILGREYRLACPEGEEEHLREAAAYVDEKMREIREKGGVLGTERLAVLAALNLADELLKLKEEL-------- 72

                         90       100
                 ....*....|....*....|..
gi 499672172  81 EEIRRTMHQMNEQLGAVLAQHE 102
Cdd:COG3027   73 EELEERLEELEEKLDEALEELE 94
 
Name Accession Description Interval E-value
ZapA COG3027
Cell division protein ZapA, inhibits GTPase activity of FtsZ [Cell cycle control, cell ...
 1-102 1.14e-23

Cell division protein ZapA, inhibits GTPase activity of FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442263 [Multi-domain]  Cd Length: 94  Bit Score: 86.47  E-value: 1.14e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499672172   1 MSTKQIEVSILGQAYRLACSAETEAALLEAVARVDAEMSKIRSNSSVRGTDRIAVMAALSLASELLRLQTSVrhgeafpa 80
Cdd:COG3027    1 MSMNRVTVTILGREYRLACPEGEEEHLREAAAYVDEKMREIREKGGVLGTERLAVLAALNLADELLKLKEEL-------- 72

                         90       100
                 ....*....|....*....|..
gi 499672172  81 EEIRRTMHQMNEQLGAVLAQHE 102
Cdd:COG3027   73 EELEERLEELEEKLDEALEELE 94
ZapA pfam05164
Cell division protein ZapA; ZapA is a cell division protein which interacts with FtsZ. FtsZ is ...
 6-94 9.47e-19

Cell division protein ZapA; ZapA is a cell division protein which interacts with FtsZ. FtsZ is part of a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the bacterial cell cycle. The interaction of FtsZ with ZapA drives its polymerization and promotes FtsZ filament bundling thereby contributing to the spatio-temporal tuning of the Z-ring.


Pssm-ID: 461565 [Multi-domain]  Cd Length: 85  Bit Score: 73.73  E-value: 9.47e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499672172    6 IEVSILGQAYRLACSAETEAALLEAVARVDAEMSKIRSNSSVRGTDRIAVMAALSLASELLRLQTSVRHGEafpaEEIRR 85
Cdd:pfam05164   1 VTVTILGREYTLACPEGEEEYLRKAAKYVDEKIKEIRESGGVLSTERLAVLAALNLADELLKLKREAEELE----EELEE 76


                  ....*....
gi 499672172   86 TMHQMNEQL 94
Cdd:pfam05164  77 RLEELAERL 85
PRK10972 PRK10972
cell division protein ZapA;
1-93 6.62e-04

cell division protein ZapA;


Pssm-ID: 182874  Cd Length: 109  Bit Score: 35.98  E-value: 6.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499672172   1 MSTKQIEVSILGQAYRLACSAETEAALLEAVARVDAEMSKIRSNSSVRGTDRIAVMAALSLASELLRLQTSVRHgEAFPA 80
Cdd:PRK10972   1 MSAQPVDIQIFGRSLRVNCPPEQRDALNQAAEDLNQRLQDLKERTRVTNTEQLVFIAALNICYELAQEKAKTRD-YAANM 79

                         90
                 ....*....|...
gi 499672172  81 EEIRRTMHQMNEQ 93
Cdd:PRK10972  80 EQRIRMLQQTIEQ 92
 
Name Accession Description Interval E-value
ZapA COG3027
Cell division protein ZapA, inhibits GTPase activity of FtsZ [Cell cycle control, cell ...
 1-102 1.14e-23

Cell division protein ZapA, inhibits GTPase activity of FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442263 [Multi-domain]  Cd Length: 94  Bit Score: 86.47  E-value: 1.14e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499672172   1 MSTKQIEVSILGQAYRLACSAETEAALLEAVARVDAEMSKIRSNSSVRGTDRIAVMAALSLASELLRLQTSVrhgeafpa 80
Cdd:COG3027    1 MSMNRVTVTILGREYRLACPEGEEEHLREAAAYVDEKMREIREKGGVLGTERLAVLAALNLADELLKLKEEL-------- 72

                         90       100
                 ....*....|....*....|..
gi 499672172  81 EEIRRTMHQMNEQLGAVLAQHE 102
Cdd:COG3027   73 EELEERLEELEEKLDEALEELE 94
ZapA pfam05164
Cell division protein ZapA; ZapA is a cell division protein which interacts with FtsZ. FtsZ is ...
 6-94 9.47e-19

Cell division protein ZapA; ZapA is a cell division protein which interacts with FtsZ. FtsZ is part of a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the bacterial cell cycle. The interaction of FtsZ with ZapA drives its polymerization and promotes FtsZ filament bundling thereby contributing to the spatio-temporal tuning of the Z-ring.


Pssm-ID: 461565 [Multi-domain]  Cd Length: 85  Bit Score: 73.73  E-value: 9.47e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499672172    6 IEVSILGQAYRLACSAETEAALLEAVARVDAEMSKIRSNSSVRGTDRIAVMAALSLASELLRLQTSVRHGEafpaEEIRR 85
Cdd:pfam05164   1 VTVTILGREYTLACPEGEEEYLRKAAKYVDEKIKEIRESGGVLSTERLAVLAALNLADELLKLKREAEELE----EELEE 76


                  ....*....
gi 499672172   86 TMHQMNEQL 94
Cdd:pfam05164  77 RLEELAERL 85
PRK10972 PRK10972
cell division protein ZapA;
1-93 6.62e-04

cell division protein ZapA;


Pssm-ID: 182874  Cd Length: 109  Bit Score: 35.98  E-value: 6.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499672172   1 MSTKQIEVSILGQAYRLACSAETEAALLEAVARVDAEMSKIRSNSSVRGTDRIAVMAALSLASELLRLQTSVRHgEAFPA 80
Cdd:PRK10972   1 MSAQPVDIQIFGRSLRVNCPPEQRDALNQAAEDLNQRLQDLKERTRVTNTEQLVFIAALNICYELAQEKAKTRD-YAANM 79

                         90
                 ....*....|...
gi 499672172  81 EEIRRTMHQMNEQ 93
Cdd:PRK10972  80 EQRIRMLQQTIEQ 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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