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Conserved domains on  [gi|499755985|ref|WP_011436719|]
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MULTISPECIES: Sec-independent protein translocase subunit TatA [Frankia]

Protein Classification

Sec-independent protein translocase family protein( domain architecture ID 241)

Sec-independent protein translocase family protein such as Sec-independent protein translocase proteins TatA and TatB, which are part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes

Gene Ontology:  GO:0033281|GO:0043953

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TatA_B_E super family cl00788
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 1-94 2.13e-19

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


The actual alignment was detected with superfamily member PRK00575:

Pssm-ID: 445098 [Multi-domain]  Cd Length: 92  Bit Score: 75.16  E-value: 2.13e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499755985  1 MGDIGAPELIIIILVVVVLFGSKRLPDAARSLGRSLRIFKSEIKGLHDDEAPAPTAAVAAAPTQVTGpaPAAPHTPPSAE 80
Cdd:PRK00575  1 MGSLSPWHWAILAVVVILLFGAKKLPDAARSLGKSLRIFKSEVKEMQSDNKAEASAAAAQAPYQVAT--PTPVQSQRVDP 78

                        90
                ....*....|....
gi 499755985 81 PATPATGGSGNRSA 94
Cdd:PRK00575 79 AAASGQDSTEARPA 92
 
Name Accession Description Interval E-value
tatA PRK00575
Sec-independent protein translocase subunit TatA;
1-94 2.13e-19

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234797 [Multi-domain]  Cd Length: 92  Bit Score: 75.16  E-value: 2.13e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499755985  1 MGDIGAPELIIIILVVVVLFGSKRLPDAARSLGRSLRIFKSEIKGLHDDEAPAPTAAVAAAPTQVTGpaPAAPHTPPSAE 80
Cdd:PRK00575  1 MGSLSPWHWAILAVVVILLFGAKKLPDAARSLGKSLRIFKSEVKEMQSDNKAEASAAAAQAPYQVAT--PTPVQSQRVDP 78

                        90
                ....*....|....
gi 499755985 81 PATPATGGSGNRSA 94
Cdd:PRK00575 79 AAASGQDSTEARPA 92
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 20-50 5.43e-09

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 47.69  E-value: 5.43e-09
                         10        20        30
                 ....*....|....*....|....*....|.
gi 499755985  20 FGSKRLPDAARSLGRSLRIFKSEIKGLHDDE 50
Cdd:pfam02416 17 FGPKKLPELGRALGKTLREFKKATKELEEED 47
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 20-49 9.86e-07

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 42.23  E-value: 9.86e-07
                        10        20        30
                ....*....|....*....|....*....|
gi 499755985 20 FGSKRLPDAARSLGRSLRIFKSEIKGLHDD 49
Cdd:COG1826  20 FGPKKLPELARSLGKAIREFKKAANEVKEE 49
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 20-49 4.91e-06

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 39.90  E-value: 4.91e-06
                         10        20        30
                 ....*....|....*....|....*....|
gi 499755985  20 FGSKRLPDAARSLGRSLRIFKSEIKGLHDD 49
Cdd:TIGR01411 18 FGAKKLPELGRDLGKAIKEFKKALKEEEDE 47
 
Name Accession Description Interval E-value
tatA PRK00575
Sec-independent protein translocase subunit TatA;
1-94 2.13e-19

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234797 [Multi-domain]  Cd Length: 92  Bit Score: 75.16  E-value: 2.13e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499755985  1 MGDIGAPELIIIILVVVVLFGSKRLPDAARSLGRSLRIFKSEIKGLHDDEAPAPTAAVAAAPTQVTGpaPAAPHTPPSAE 80
Cdd:PRK00575  1 MGSLSPWHWAILAVVVILLFGAKKLPDAARSLGKSLRIFKSEVKEMQSDNKAEASAAAAQAPYQVAT--PTPVQSQRVDP 78

                        90
                ....*....|....
gi 499755985 81 PATPATGGSGNRSA 94
Cdd:PRK00575 79 AAASGQDSTEARPA 92
tatA PRK00191
twin arginine translocase protein A; Provisional
 20-50 3.12e-13

twin arginine translocase protein A; Provisional


Pssm-ID: 234683 [Multi-domain]  Cd Length: 84  Bit Score: 59.20  E-value: 3.12e-13
                        10        20        30
                ....*....|....*....|....*....|.
gi 499755985 20 FGSKRLPDAARSLGRSLRIFKSEIKGLHDDE 50
Cdd:PRK00191 19 FGAKKLPDAARSIGRSMRIFKSEVKEMSKDD 49
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 20-50 5.43e-09

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 47.69  E-value: 5.43e-09
                         10        20        30
                 ....*....|....*....|....*....|.
gi 499755985  20 FGSKRLPDAARSLGRSLRIFKSEIKGLHDDE 50
Cdd:pfam02416 17 FGPKKLPELGRALGKTLREFKKATKELEEED 47
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 20-49 9.86e-07

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 42.23  E-value: 9.86e-07
                        10        20        30
                ....*....|....*....|....*....|
gi 499755985 20 FGSKRLPDAARSLGRSLRIFKSEIKGLHDD 49
Cdd:COG1826  20 FGPKKLPELARSLGKAIREFKKAANEVKEE 49
tatA PRK14861
twin arginine translocase protein A; Provisional
 1-50 1.65e-06

twin arginine translocase protein A; Provisional


Pssm-ID: 237837  Cd Length: 61  Bit Score: 41.49  E-value: 1.65e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 499755985  1 MGDIGAPELIIIILVVVVLFGSKRLPDAARSLGRSLRIFKSEIKGLHDDE 50
Cdd:PRK14861  2 FSNIGFPGLILILVVALIIFGPKKLPELGKALGKTLREFKKATKELTDDD 51
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 20-49 4.91e-06

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 39.90  E-value: 4.91e-06
                         10        20        30
                 ....*....|....*....|....*....|
gi 499755985  20 FGSKRLPDAARSLGRSLRIFKSEIKGLHDD 49
Cdd:TIGR01411 18 FGAKKLPELGRDLGKAIKEFKKALKEEEDE 47
tatA PRK14857
TatA/E family twin arginine-targeting protein translocase;
4-41 2.36e-03

TatA/E family twin arginine-targeting protein translocase;


Pssm-ID: 184859  Cd Length: 90  Bit Score: 33.93  E-value: 2.36e-03
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 499755985  4 IGAPELIIIILVVVVLFGSKRLPDAARSLGRSLRIFKS 41
Cdd:PRK14857  6 IGLPEMAVILVIALLVFGPKKLPEIGRSLGKTLKGFQE 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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