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Conserved domains on  [gi|499968818|ref|WP_011649536|]
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MULTISPECIES: helix-turn-helix transcriptional regulator [Rhizobium]

Protein Classification

ArsR/SmtB family transcription factor( domain architecture ID 10001925)

ArsR (Arsenical Resistance Operon Repressor)/SmtB family transcription factor is a winged-helix-turn-helix transcriptional regulator that may be metal-sensing and modulate the expression of genes associated with metal homeostasis

Gene Ontology:  GO:0003700|GO:0006355|GO:0003677
PubMed:  10473770|28436329|12829264|28512703|30191942|15808743

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ArsR COG0640
DNA-binding transcriptional regulator, ArsR family [Transcription];
11-101 1.02e-26

DNA-binding transcriptional regulator, ArsR family [Transcription];


:

Pssm-ID: 440405 [Multi-domain]  Cd Length: 92  Bit Score: 94.57  E-value: 1.02e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499968818  11 PETNAFDNEANFLSAMGNAKRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSLQSAAA 90
Cdd:COG0640    2 SETKELEELAELFKALADPTRLRILRLLAEGELCVGELAEALGLSQSTVSHHLKVLREAGLVTSRREGRWVYYRLADEAL 81

                         90
                 ....*....|.
gi 499968818  91 TAMLDTLAEIF 101
Cdd:COG0640   82 AELLEWLLELL 92
 
Name Accession Description Interval E-value
ArsR COG0640
DNA-binding transcriptional regulator, ArsR family [Transcription];
11-101 1.02e-26

DNA-binding transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 440405 [Multi-domain]  Cd Length: 92  Bit Score: 94.57  E-value: 1.02e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499968818  11 PETNAFDNEANFLSAMGNAKRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSLQSAAA 90
Cdd:COG0640    2 SETKELEELAELFKALADPTRLRILRLLAEGELCVGELAEALGLSQSTVSHHLKVLREAGLVTSRREGRWVYYRLADEAL 81

                         90
                 ....*....|.
gi 499968818  91 TAMLDTLAEIF 101
Cdd:COG0640   82 AELLEWLLELL 92
HTH_metalloreg NF033788
metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense ...
 20-94 4.98e-25

metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense toxic heavy metals such as arsenic or cadmium, and are released from DNA so that resistance factors will be expressed, include ArsR, SmtB, ZiaR, CadC, CadX, KmtR, etc. However, some members of this family, including the sporulation delaying system autorepressor SdpR and its family (see NF033789), may lack metal-binding cites and instead regulate other cellular processes.


Pssm-ID: 411368 [Multi-domain]  Cd Length: 76  Bit Score: 89.83  E-value: 4.98e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499968818  20 ANFLSAMGNAKRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSLQSAAATAML 94
Cdd:NF033788   2 AELFKALADPTRLRILELLAEGELCVCELAEALGLSQSAVSQHLKVLRDAGLVTSRREGRWVYYRLADEHVAELL 76
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 23-85 5.14e-20

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 77.34  E-value: 5.14e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499968818  23 LSAMGNAKRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSL 85
Cdd:cd00090    1 LKALSDPTRLRILRLLLEGPLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRREGRRVYYSL 63
HTH_ARSR smart00418
helix_turn_helix, Arsenical Resistance Operon Repressor;
34-85 6.45e-19

helix_turn_helix, Arsenical Resistance Operon Repressor;


Pssm-ID: 197713 [Multi-domain]  Cd Length: 66  Bit Score: 74.17  E-value: 6.45e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 499968818    34 ILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSL 85
Cdd:smart00418   2 ILKLLAEGELCVCELAEILGLSQSTVSHHLKKLREAGLVESRREGKRVYYSL 53
repress_SdpR NF033789
autorepressor SdpR family transcription factor; Transcription factors in the family of the ...
 25-85 1.33e-14

autorepressor SdpR family transcription factor; Transcription factors in the family of the sporulation delaying system autorepressor SdpR (of Bacillus subtilis) resemble metalloregulatory transcriptional repressors such as ArsR, SmtB, CadX, ZiaR, etc., but may lack the key metal-binding residues.


Pssm-ID: 411369 [Multi-domain]  Cd Length: 79  Bit Score: 63.20  E-value: 1.33e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499968818  25 AMGNAKRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSL 85
Cdd:NF033789   4 ALSDPTRREILELLKEGDMTAGEIAEHFDMSKPSISHHLNILKQADLVTDERKGQFIYYSL 64
HTH_5 pfam01022
Bacterial regulatory protein, arsR family; Members of this family contains a DNA binding ...
 30-72 1.69e-14

Bacterial regulatory protein, arsR family; Members of this family contains a DNA binding 'helix-turn-helix' motif. This family includes other proteins which are not included in the Prosite definition.


Pssm-ID: 425993 [Multi-domain]  Cd Length: 45  Bit Score: 62.08  E-value: 1.69e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 499968818   30 KRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELV 72
Cdd:pfam01022   3 TRLKILKLLAEGELCVCELAEELGLSQSTVSHHLKKLREAGLV 45
PRK10141 PRK10141
DNA-binding transcriptional repressor ArsR; Provisional
 31-85 1.36e-07

DNA-binding transcriptional repressor ArsR; Provisional


Pssm-ID: 236654  Cd Length: 117  Bit Score: 46.35  E-value: 1.36e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 499968818  31 RLHILHLLAE-GEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSL 85
Cdd:PRK10141  18 RLGIVLLLREsGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRL 73
cas_HTH TIGR01884
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ...
 30-72 1.33e-05

CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]


Pssm-ID: 273852 [Multi-domain]  Cd Length: 203  Bit Score: 41.96  E-value: 1.33e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 499968818   30 KRLHILHLL-AEGEMSVSVLADEVGLSQSSTSQHLAILREQELV 72
Cdd:TIGR01884 144 EELKILEVLkATGEKSVKNIAKKLGKSLSTISRHLAELEKKGLV 187
 
Name Accession Description Interval E-value
ArsR COG0640
DNA-binding transcriptional regulator, ArsR family [Transcription];
11-101 1.02e-26

DNA-binding transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 440405 [Multi-domain]  Cd Length: 92  Bit Score: 94.57  E-value: 1.02e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499968818  11 PETNAFDNEANFLSAMGNAKRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSLQSAAA 90
Cdd:COG0640    2 SETKELEELAELFKALADPTRLRILRLLAEGELCVGELAEALGLSQSTVSHHLKVLREAGLVTSRREGRWVYYRLADEAL 81

                         90
                 ....*....|.
gi 499968818  91 TAMLDTLAEIF 101
Cdd:COG0640   82 AELLEWLLELL 92
HTH_metalloreg NF033788
metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense ...
 20-94 4.98e-25

metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense toxic heavy metals such as arsenic or cadmium, and are released from DNA so that resistance factors will be expressed, include ArsR, SmtB, ZiaR, CadC, CadX, KmtR, etc. However, some members of this family, including the sporulation delaying system autorepressor SdpR and its family (see NF033789), may lack metal-binding cites and instead regulate other cellular processes.


Pssm-ID: 411368 [Multi-domain]  Cd Length: 76  Bit Score: 89.83  E-value: 4.98e-25
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 499968818  20 ANFLSAMGNAKRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSLQSAAATAML 94
Cdd:NF033788   2 AELFKALADPTRLRILELLAEGELCVCELAEALGLSQSAVSQHLKVLRDAGLVTSRREGRWVYYRLADEHVAELL 76
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 23-85 5.14e-20

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 77.34  E-value: 5.14e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 499968818  23 LSAMGNAKRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSL 85
Cdd:cd00090    1 LKALSDPTRLRILRLLLEGPLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRREGRRVYYSL 63
HTH_ARSR smart00418
helix_turn_helix, Arsenical Resistance Operon Repressor;
34-85 6.45e-19

helix_turn_helix, Arsenical Resistance Operon Repressor;


Pssm-ID: 197713 [Multi-domain]  Cd Length: 66  Bit Score: 74.17  E-value: 6.45e-19
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 499968818    34 ILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSL 85
Cdd:smart00418   2 ILKLLAEGELCVCELAEILGLSQSTVSHHLKKLREAGLVESRREGKRVYYSL 53
repress_SdpR NF033789
autorepressor SdpR family transcription factor; Transcription factors in the family of the ...
 25-85 1.33e-14

autorepressor SdpR family transcription factor; Transcription factors in the family of the sporulation delaying system autorepressor SdpR (of Bacillus subtilis) resemble metalloregulatory transcriptional repressors such as ArsR, SmtB, CadX, ZiaR, etc., but may lack the key metal-binding residues.


Pssm-ID: 411369 [Multi-domain]  Cd Length: 79  Bit Score: 63.20  E-value: 1.33e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499968818  25 AMGNAKRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSL 85
Cdd:NF033789   4 ALSDPTRREILELLKEGDMTAGEIAEHFDMSKPSISHHLNILKQADLVTDERKGQFIYYSL 64
HTH_5 pfam01022
Bacterial regulatory protein, arsR family; Members of this family contains a DNA binding ...
 30-72 1.69e-14

Bacterial regulatory protein, arsR family; Members of this family contains a DNA binding 'helix-turn-helix' motif. This family includes other proteins which are not included in the Prosite definition.


Pssm-ID: 425993 [Multi-domain]  Cd Length: 45  Bit Score: 62.08  E-value: 1.69e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 499968818   30 KRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELV 72
Cdd:pfam01022   3 TRLKILKLLAEGELCVCELAEELGLSQSTVSHHLKKLREAGLV 45
COG4189 COG4189
Predicted transcriptional regulator, ArsR family [Transcription];
23-84 4.28e-13

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 443343 [Multi-domain]  Cd Length: 97  Bit Score: 59.97  E-value: 4.28e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 499968818  23 LSAMGNAKRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQT-----RRAAQTIYYS 84
Cdd:COG4189   13 LKALASETRLRILRLLAEEPLNVNELAEALGLPKSTVSYHIRKLEEAGLIRTeykpgKRGRQKICYL 79
HTH_20 pfam12840
Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in ...
 20-76 1.75e-08

Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.


Pssm-ID: 432824 [Multi-domain]  Cd Length: 61  Bit Score: 47.15  E-value: 1.75e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 499968818   20 ANFLSAMGNAKRLHILHLLAEGE-MSVSVLADEVGLSQSSTSQHLAILREQELVQTRR 76
Cdd:pfam12840   1 DDVAEALADPTRLRILRALVGDEpLTASELARRLDISRNTLSYHLRKLEEAGLVEVVR 58
COG3398 COG3398
Predicted transcriptional regulator, contains two HTH domains [Transcription];
17-85 6.00e-08

Predicted transcriptional regulator, contains two HTH domains [Transcription];


Pssm-ID: 442625 [Multi-domain]  Cd Length: 159  Bit Score: 47.95  E-value: 6.00e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499968818  17 DNEANFLSAMGN--AKRLhILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSL 85
Cdd:COG3398   85 EEEKKILAYLRRetPRRI-LLYLLENPGATNKELAEELGISRSTVSWHLKRLEEDGLVERERDGRNVRYYL 154
PRK10141 PRK10141
DNA-binding transcriptional repressor ArsR; Provisional
 31-85 1.36e-07

DNA-binding transcriptional repressor ArsR; Provisional


Pssm-ID: 236654  Cd Length: 117  Bit Score: 46.35  E-value: 1.36e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 499968818  31 RLHILHLLAE-GEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSL 85
Cdd:PRK10141  18 RLGIVLLLREsGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRL 73
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
18-102 8.09e-07

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 45.68  E-value: 8.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499968818  18 NEANFLSAMGNAKRLHILHLLAE-GEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQ-----TIYYSLQSAA-- 89
Cdd:COG2345    2 TDTPALAALADPTRRRILELLKRaGPVTAAELAEALGLTPNAVRRHLDALEEEGLVERETERRgrgrpAKLYRLTEAGra 81

                         90       100
                 ....*....|....*....|..
gi 499968818  90 ---------ATAMLDTLAEIFG 102
Cdd:COG2345   82 rfprayddlAVALLDALRELLG 103
COG2512 COG2512
Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain ...
 33-85 5.08e-06

Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain [General function prediction only];


Pssm-ID: 442002 [Multi-domain]  Cd Length: 80  Bit Score: 41.44  E-value: 5.08e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 499968818  33 HILHLLAE--GEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSL 85
Cdd:COG2512   19 RVLELLREngGRMTQSEIVKETGWSKSKVSRLLSRLEERGLIEKERVGRENVVEL 73
cas_HTH TIGR01884
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ...
 30-72 1.33e-05

CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]


Pssm-ID: 273852 [Multi-domain]  Cd Length: 203  Bit Score: 41.96  E-value: 1.33e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 499968818   30 KRLHILHLL-AEGEMSVSVLADEVGLSQSSTSQHLAILREQELV 72
Cdd:TIGR01884 144 EELKILEVLkATGEKSVKNIAKKLGKSLSTISRHLAELEKKGLV 187
COG4742 COG4742
Predicted transcriptional regulator, contains HTH domain [Transcription];
30-72 2.20e-05

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 443776 [Multi-domain]  Cd Length: 267  Bit Score: 41.80  E-value: 2.20e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 499968818  30 KRLHILHLLAEGEMSVSVLADEVGLSQSSTSQHLAILREQELV 72
Cdd:COG4742   17 KRKNILLLLAEGPKTRSELAESLDVSRSTILRQLKELEERGLI 59
CasRa_I-A cd09655
CRISPR/Cas system-associated transcriptional regulator CasRa; CRISPR (Clustered Regularly ...
 30-72 5.17e-05

CRISPR/Cas system-associated transcriptional regulator CasRa; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Predicted transcriptional regulator of CRISPR/Cas system


Pssm-ID: 187786 [Multi-domain]  Cd Length: 198  Bit Score: 40.44  E-value: 5.17e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 499968818  30 KRLHILHLL-AEGEMSVSVLADEVGLSQSSTSQHLAILREQELV 72
Cdd:cd09655  140 EELKILEVLkAKGEKSVKNIAKKLGKSLSTISRHLRELEKKGLV 183
PHA00738 PHA00738
putative HTH transcription regulator
 31-89 1.22e-04

putative HTH transcription regulator


Pssm-ID: 177305  Cd Length: 108  Bit Score: 38.41  E-value: 1.22e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 499968818  31 RLHILHLLAEG-EMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQTIYYSLQSAA 89
Cdd:PHA00738  14 RRKILELIAENyILSASLISHTLLLSYTTVLRHLKILNEQGYIELYKEGRTLYAKIRENS 73
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
31-79 2.38e-04

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 38.03  E-value: 2.38e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 499968818  31 RLHILHLLAE-GEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRAAQ 79
Cdd:COG1846   40 QFRVLAALAEaGGLTQSELAERLGLTKSTVSRLLDRLEEKGLVEREPDPE 89
HTH_24 pfam13412
Winged helix-turn-helix DNA-binding;
30-72 4.93e-04

Winged helix-turn-helix DNA-binding;


Pssm-ID: 404317 [Multi-domain]  Cd Length: 45  Bit Score: 35.10  E-value: 4.93e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 499968818   30 KRLHILHLLAE-GEMSVSVLADEVGLSQSSTSQHLAILREQELV 72
Cdd:pfam13412   2 TDRKILNLLQEnPRISQRELAERLGLSPSTVNRRLKRLEEEGVI 45
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
28-76 1.49e-03

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 35.26  E-value: 1.49e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 499968818    28 NAKRLHILHLLAE-GEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRR 76
Cdd:smart00347   9 TPTQFLVLRILYEeGPLSVSELAKRLGVSPSTVTRVLDRLEKKGLVRREP 58
BirA COG1654
Biotin operon repressor [Transcription];
26-69 2.79e-03

Biotin operon repressor [Transcription];


Pssm-ID: 441260 [Multi-domain]  Cd Length: 324  Bit Score: 35.73  E-value: 2.79e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 499968818  26 MGNAKRLHILHLLAEGE-MSVSVLADEVGLSQSSTSQHLAILREQ 69
Cdd:COG1654    1 MMSSTRLKLLRLLADGEfHSGEELAEELGVSRAAVWKHIKALREL 45
Lrp COG1522
DNA-binding transcriptional regulator, Lrp family [Transcription];
32-77 8.80e-03

DNA-binding transcriptional regulator, Lrp family [Transcription];


Pssm-ID: 441131 [Multi-domain]  Cd Length: 138  Bit Score: 33.60  E-value: 8.80e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 499968818  32 LHILHLLAE-GEMSVSVLADEVGLSQSSTSQHLAILREQELVQTRRA 77
Cdd:COG1522    8 RRILRLLQEdGRLSFAELAERVGLSESTVLRRVRRLEEAGVIRGYGA 54
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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