|
Name |
Accession |
Description |
Interval |
E-value |
| CaiB |
COG1804 |
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid ... |
395-788 |
4.19e-99 |
|
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid transport and metabolism];
Pssm-ID: 441409 Cd Length: 397 Bit Score: 312.82 E-value: 4.19e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 395 LPLEGLRVLDLGVIVVGADTGRLFADLGADVIKIENSAFPDGLRG---RLNMMSQTYASGHRNKRSIGIDLRSDEGRALA 471
Cdd:COG1804 5 GPLAGIRVLDLSRVLAGPFATMLLADLGADVIKVERPGGGDPTRGwgpPFDGESAYFLSLNRNKRSITLDLKSPEGRELL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 472 HRLAEDADVVLTNFKPGVAQALGMDFGSLKKVNPGIVVVDSSAFGPTGPWARRLGYGPLVRAAAGFTDLWVYPDAPgefc 551
Cdd:COG1804 85 RRLVARADVLVENFRPGVLERLGLGYEALRAINPRLIYCSISGFGQTGPYADRPGYDLIAQAMSGLMSLTGEPDGP---- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 552 dtvTVYP-----DHVAARIGALTALTLLLRRERTGTGGAVSVAQSEVMLSHLAGEIAA-----EVLQRQGHARSdepvHD 621
Cdd:COG1804 161 ---PVRVgvsvaDIAAGLYAAIGILAALLHRERTGRGQVVDVSLLDAALALLANQAAEylatgEVPERTGNRHP----GI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 622 APWGLFPAegEDKWVAVTVRDTTDWQALCGVIGRADLAADDALNTPAGRDADRARIDEAVRAWTSARTATAAMELLQKAG 701
Cdd:COG1804 234 APYGVYRT--ADGWVAIAAGNDRQWRRLCEALGRPDLADDPRFATNAARVANRDELDALLAAWFATRTRAEWLELLEAAG 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 702 VPAGAVLHAGEVPNFGYYAERRAFREELHPHAAePFMMENVQIHSDRVADPPLGQAPLLGEQTREIAAElLGLSDAEIDE 781
Cdd:COG1804 312 VPAAPVNTLAEVLADPQLAARGMFVEVDHPDGG-PVRQPGPPPRFSGTPGRVRRPAPALGEHTDEVLAE-LGYSAEEIAA 389
|
....*..
gi 500047277 782 LIERGVL 788
Cdd:COG1804 390 LRAAGVI 396
|
|
| CoA_transf_3 |
pfam02515 |
CoA-transferase family III; CoA-transferases are found in organizms from all lines of descent. ... |
397-764 |
4.16e-77 |
|
CoA-transferase family III; CoA-transferases are found in organizms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.
Pssm-ID: 426810 [Multi-domain] Cd Length: 367 Bit Score: 253.68 E-value: 4.16e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 397 LEGLRVLDLGVIVVGADTGRLFADLGADVIKIENSAfPDGLRG----RLNMMSQTYASGHRNKRSIGIDLRSDEGRALAH 472
Cdd:pfam02515 1 LAGIRVLDLTQVVAGPFATMLLADLGAEVIKVEPPG-GDPTRYvgpyAEKGGSAYFLSVNRNKRSVALDLKSEEGREVLR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 473 RLAEDADVVLTNFKPGVAQALGMDFGSLKKVNPGIVVVDSSAFGPTGPWARRLGYGPLVRAAAGFTDLWVYPDAPGEFCD 552
Cdd:pfam02515 80 RLVARADVVIENFRPGVLERLGLGYEDLRAINPRLIYCSVSGYGQTGPYADRPGYDLIAQAMSGLMSLTGEPGGPPVKVG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 553 TVTVypDHVAARIGALTALTLLLRRERTGTGGAVSVAQSEVMLSHLAGEIAA-----EVLQRQGHARSDEpvhdAPWGLF 627
Cdd:pfam02515 160 TPVG--DIVTGLLAAIAILAALLARERTGKGQVIDVSLLEAALALMGPQLLEylatgRVPGRVGNRHPAA----APYGLY 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 628 PAegEDKWVAVTVRDTTDWQALCGVIGRADLAADDALNTPAGRDADRARIDEAVRAWTSARTATAAMELLQKAGVPAGAV 707
Cdd:pfam02515 234 RT--ADGWVAIAAGTDKQWARLCRALGRPELADDPRFATNAARVQNRAELDAELAAWLATRTAAEWLALLAAAGVPAGPV 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 500047277 708 LHAGEVPNFGYYAERRAFREELHPHaAEPFMMENVQIHSDRVADPPLGQAPLLGEQT 764
Cdd:pfam02515 312 NTVEEVLDDPHLRARGMVVEVDHPD-YGPVPVPGLPVRLSGTPGRVRRPAPALGEHT 367
|
|
| CaiB |
COG1804 |
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid ... |
10-372 |
8.10e-49 |
|
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid transport and metabolism];
Pssm-ID: 441409 Cd Length: 397 Bit Score: 177.61 E-value: 8.10e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 10 PLSGVKVLDLSS---GPITavGRLLADLGAQVTPVNLAGVTEAGATVGPRIGAVPVG-TAINRFGLStVDLDTSTADGAR 85
Cdd:COG1804 6 PLAGIRVLDLSRvlaGPFA--TMLLADLGADVIKVERPGGGDPTRGWGPPFDGESAYfLSLNRNKRS-ITLDLKSPEGRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 86 RWRELLADADILIENTRPGSDAEKALSAREIHADHPSLVILSVSDFGRDTAYRTWQATTPVLHALTSELSRSGIPGREPL 165
Cdd:COG1804 83 LLRRLVARADVLVENFRPGVLERLGLGYEALRAINPRLIYCSISGFGQTGPYADRPGYDLIAQAMSGLMSLTGEPDGPPV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 166 VPPAPQlpyqvaaaqaAVMTVSVY---------LDRLRTGTGDLIDFSVLDGAMQTLDPPFGTpGTASAGVPlaEQRRNW 236
Cdd:COG1804 163 RVGVSV----------ADIAAGLYaaigilaalLHRERTGRGQVVDVSLLDAALALLANQAAE-YLATGEVP--ERTGNR 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 237 LAERQRYPIVRCKDGYVRICVLAKRQWQGMFTWMGEPEEFADPKFNSLMERFM-SPTLLPAIERFCADKTRAELEAEGQR 315
Cdd:COG1804 230 HPGIAPYGVYRTADGWVAIAAGNDRQWRRLCEALGRPDLADDPRFATNAARVAnRDELDALLAAWFATRTRAEWLELLEA 309
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 500047277 316 HGVPTAAVLTLTEALDTEQVKERGFFREVELANGFTAPVPVGVSEVDGHRASALTAP 372
Cdd:COG1804 310 AGVPAAPVNTLAEVLADPQLAARGMFVEVDHPDGGPVRQPGPPPRFSGTPGRVRRPA 366
|
|
| CoA_transf_3 |
pfam02515 |
CoA-transferase family III; CoA-transferases are found in organizms from all lines of descent. ... |
11-373 |
1.14e-44 |
|
CoA-transferase family III; CoA-transferases are found in organizms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.
Pssm-ID: 426810 [Multi-domain] Cd Length: 367 Bit Score: 165.09 E-value: 1.14e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 11 LSGVKVLDLSS---GPITAvgRLLADLGAQVTPVNLAGVTEA---GATVGPRIGAVPVGTAINRFGLStvdLDTSTADGA 84
Cdd:pfam02515 1 LAGIRVLDLTQvvaGPFAT--MLLADLGAEVIKVEPPGGDPTryvGPYAEKGGSAYFLSVNRNKRSVA---LDLKSEEGR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 85 RRWRELLADADILIENTRPGSDAEKALSAREIHADHPSLVILSVSDFGRDTAYRTWQATTPVLHALTSELSRSGIPGREP 164
Cdd:pfam02515 76 EVLRRLVARADVVIENFRPGVLERLGLGYEDLRAINPRLIYCSVSGYGQTGPYADRPGYDLIAQAMSGLMSLTGEPGGPP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 165 LVPPAPQLPYQVAAAQAAVMtVSVYLDRLRTGTGDLIDFSVLDGAMQTLDPPFG-TPGTASAGVPLAEQRRNWlaerQRY 243
Cdd:pfam02515 156 VKVGTPVGDIVTGLLAAIAI-LAALLARERTGKGQVIDVSLLEAALALMGPQLLeYLATGRVPGRVGNRHPAA----APY 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 244 PIVRCKDGYVRICVLAKRQWQGMFTWMGEPEEFADPKFNSLMERF-MSPTLLPAIERFCADKTRAELEAEGQRHGVPTAA 322
Cdd:pfam02515 231 GLYRTADGWVAIAAGTDKQWARLCRALGRPELADDPRFATNAARVqNRAELDAELAAWLATRTAAEWLALLAAAGVPAGP 310
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 500047277 323 VLTLTEALDTEQVKERGFFREVELANGFTAPV---PVGVSEVDGHRASAltAPR 373
Cdd:pfam02515 311 VNTVEEVLDDPHLRARGMVVEVDHPDYGPVPVpglPVRLSGTPGRVRRP--APA 362
|
|
| PRK05398 |
PRK05398 |
formyl-coenzyme A transferase; Provisional |
394-788 |
3.85e-34 |
|
formyl-coenzyme A transferase; Provisional
Pssm-ID: 180055 Cd Length: 416 Bit Score: 135.87 E-value: 3.85e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 394 GLPLEGLRVLDLGVIVVGADTGRLFADLGADVIKIENSAFPDGLRGRLNMMSQTYA----SGHRNKRSIGIDLRSDEGRA 469
Cdd:PRK05398 2 TKPLEGIKVLDFTHVQSGPSCTQLLAWFGADVIKVERPGVGDVTRNQLRDIPDVDSlyftMLNSNKRSITLDTKTPEGKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 470 LAHRLAEDADVVLTNFKPGVAQALGMDFGSLKKVNPGIVVVDSSAFGPTGPWARRLGYGPLVRAAAG---FTDLWvypDA 546
Cdd:PRK05398 82 VLEKLIREADVLVENFGPGALDRMGFTWERIQEINPRLIVASIKGFGPGSPYEDVKAYENVAQCAGGaasTTGFW---DG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 547 PgefcDTVTvypdhvAARIGAltaltlllrrerTGTGgavsvaqsevmlSHLAGEIAAEVLQRQGHARS---DEPVHDA- 622
Cdd:PRK05398 159 P----PTVS------GAALGD------------SNTG------------MHLAIGILAALLQREKTGRGqrvTVSMQDAv 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 623 ------------------PWGLFPAEGEDKW--------------------------------VAVTVRDTTdWQALCGV 652
Cdd:PRK05398 205 lnlcrvklrdqqrldhlgYLEEYPQYPNGTFgdavpragnasgggqpgwilkckgwetdpnayIYFIIQPQG-WEPICKA 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 653 IGRADLAADDALNTPAGRDADRARIDEAVRAWTSARTATAAMELLQKAGVPAGAVLHAGEVPNFGYYAERRAFREELHPH 732
Cdd:PRK05398 284 IGKPEWITDPAYATPEARQPHLFDIFAEIEKWTMTKTKFEAVDILNAFDIPCGPVLSMKEIAEDPSLRASGTIVEVDHPL 363
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 500047277 733 AAE------PFMMENVQihsdrvadPPLGQAPLLGEQTREIAAElLGLSDAEIDELIERGVL 788
Cdd:PRK05398 364 RGKyltvgsPIKLSDSP--------PDVKRSPLLGEHTDEVLAE-LGYSDDQIAALKQNGAI 416
|
|
| PRK11430 |
PRK11430 |
putative CoA-transferase; Provisional |
10-362 |
6.75e-16 |
|
putative CoA-transferase; Provisional
Pssm-ID: 183132 [Multi-domain] Cd Length: 381 Bit Score: 80.41 E-value: 6.75e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 10 PLSGVKVLDLS---SGPITAvgRLLADLGAQVTPVNLAGVTEAGATVGPRIGAVPVGTAINRFGLSTVDLDTSTADGARR 86
Cdd:PRK11430 9 PFEGLLVIDMThvlNGPFGT--QLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 87 WRELLADADILIENTRPGSDAEKALSAREIHADHPSLVILSVSDFGRDTAYRTWQATTPVLHALTSELSRSGIPGREPlV 166
Cdd:PRK11430 87 FINMLKQADVLAENFRPGTMEKLGFSWETLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPDAPP-V 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 167 PPAPQLPYQVAAAQAAVMTVSVYLDRLRTGTGDLIDFSVLDGAMQTLDPPFgtpgTASAGVPLAEQRrnwLAERQRY--- 243
Cdd:PRK11430 166 RVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGL----MAYIATGKSPQR---LGNRHPYmap 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 244 -PIVRCKDGYVRICVLAKRQWQGMFTWMGEPEEFADPKFNSLMERFMSPTLLPA-IERFCADKTRAELEAEGQRHGVPTA 321
Cdd:PRK11430 239 fDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQyIERTLKTQAAEVWLARIHEVGVPVA 318
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 500047277 322 AVLTLTEALDTEQVKERGFFREvelANGFTAP-VPVGVSEVD 362
Cdd:PRK11430 319 PLLSVAEAINLPQTQARNMLIE---AGGIMMPgNPIKISGCA 357
|
|
| mesacon_CoA_iso |
TIGR04253 |
mesaconyl-CoA isomerase; Members of this protein family belong by homology to the family of ... |
397-791 |
3.43e-11 |
|
mesaconyl-CoA isomerase; Members of this protein family belong by homology to the family of CoA transferases. However, the characterized member from Chloroflexus aurantiacus appears to perform an intramolecular transfer, making it an isomerase. The enzyme converts mesaconyl-C1-CoA to mesaconyl-C4-CoA as part of the bicyclic 3-hydroxyproprionate pathway for carbon fixation.
Pssm-ID: 211976 Cd Length: 403 Bit Score: 66.14 E-value: 3.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 397 LEGLRVLDLGVIVVGADTGRLFADLGADVIK-------IENSAFPDGLRGRLNMMsqtYASGHRNKRSIGIDLRSDEGRA 469
Cdd:TIGR04253 3 LHGLRVVEGSAFVAAPLGGMTLAQLGADVIRfdpigggLDYKRWPLTLDGKHSLF---WAGLNKGKRSIAIDIRHPRGQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 470 LAHRL----AEDADVVLTNFKpgvaqALG-MDFGSLKKVNPGIVVVDSSAfgptgpwaRRLGYGPL---VRAAAGFTdLW 541
Cdd:TIGR04253 80 LLTQLicapGDHAGLFITNFP-----AKGwLAYDALKAHRADLIMVNLTG--------RRDGGSEVdytLNPQLGLP-FM 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 542 VYPDAPGEFCDTVTVYPDHVAARIGALTALTLLLRRERTGTGGAVSVAQSEV---MLSHLAgeIAAEVL------QRQGH 612
Cdd:TIGR04253 146 TGPTSSPDVVNHVFPAWDFISGQMIALGLLAAERHRRLTGEGQLVKIALKDValaMIGHFG--MIAEAMindadrPRQGN 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 613 ArsdepvhdapwgLFPAEGED------KWVAVTVRDTTDWQALCGVIGRAD----LAADDALNTPAGRDADRAR--IDEA 680
Cdd:TIGR04253 224 Y------------LYGAFGRDfetldgKRLMVVGLTDLQWKALGKATGLRDafnaLAARLGLDFDDEGDRFRARheIAAL 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 681 VRAWTSARTATAAMELLQKAGVPagavlhagevpnfgyYAERRAFREELhphAAEP-------------------FMMEN 741
Cdd:TIGR04253 292 FEPWFHARTLAEAALIFDAHGVT---------------WAPYRSVREAI---AADPdcstdnpmfalteqpgigrYLMPG 353
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 500047277 742 VQIHSDRVADPPLGQAPLLGEQTREIAAELLGLSDAEIDELIERGVLEMP 791
Cdd:TIGR04253 354 SPLDFAAVPRLPAMPAPRLGEHTDEILLDILGLSEAEVGRLHDAGIVAGP 403
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CaiB |
COG1804 |
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid ... |
395-788 |
4.19e-99 |
|
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid transport and metabolism];
Pssm-ID: 441409 Cd Length: 397 Bit Score: 312.82 E-value: 4.19e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 395 LPLEGLRVLDLGVIVVGADTGRLFADLGADVIKIENSAFPDGLRG---RLNMMSQTYASGHRNKRSIGIDLRSDEGRALA 471
Cdd:COG1804 5 GPLAGIRVLDLSRVLAGPFATMLLADLGADVIKVERPGGGDPTRGwgpPFDGESAYFLSLNRNKRSITLDLKSPEGRELL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 472 HRLAEDADVVLTNFKPGVAQALGMDFGSLKKVNPGIVVVDSSAFGPTGPWARRLGYGPLVRAAAGFTDLWVYPDAPgefc 551
Cdd:COG1804 85 RRLVARADVLVENFRPGVLERLGLGYEALRAINPRLIYCSISGFGQTGPYADRPGYDLIAQAMSGLMSLTGEPDGP---- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 552 dtvTVYP-----DHVAARIGALTALTLLLRRERTGTGGAVSVAQSEVMLSHLAGEIAA-----EVLQRQGHARSdepvHD 621
Cdd:COG1804 161 ---PVRVgvsvaDIAAGLYAAIGILAALLHRERTGRGQVVDVSLLDAALALLANQAAEylatgEVPERTGNRHP----GI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 622 APWGLFPAegEDKWVAVTVRDTTDWQALCGVIGRADLAADDALNTPAGRDADRARIDEAVRAWTSARTATAAMELLQKAG 701
Cdd:COG1804 234 APYGVYRT--ADGWVAIAAGNDRQWRRLCEALGRPDLADDPRFATNAARVANRDELDALLAAWFATRTRAEWLELLEAAG 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 702 VPAGAVLHAGEVPNFGYYAERRAFREELHPHAAePFMMENVQIHSDRVADPPLGQAPLLGEQTREIAAElLGLSDAEIDE 781
Cdd:COG1804 312 VPAAPVNTLAEVLADPQLAARGMFVEVDHPDGG-PVRQPGPPPRFSGTPGRVRRPAPALGEHTDEVLAE-LGYSAEEIAA 389
|
....*..
gi 500047277 782 LIERGVL 788
Cdd:COG1804 390 LRAAGVI 396
|
|
| CoA_transf_3 |
pfam02515 |
CoA-transferase family III; CoA-transferases are found in organizms from all lines of descent. ... |
397-764 |
4.16e-77 |
|
CoA-transferase family III; CoA-transferases are found in organizms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.
Pssm-ID: 426810 [Multi-domain] Cd Length: 367 Bit Score: 253.68 E-value: 4.16e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 397 LEGLRVLDLGVIVVGADTGRLFADLGADVIKIENSAfPDGLRG----RLNMMSQTYASGHRNKRSIGIDLRSDEGRALAH 472
Cdd:pfam02515 1 LAGIRVLDLTQVVAGPFATMLLADLGAEVIKVEPPG-GDPTRYvgpyAEKGGSAYFLSVNRNKRSVALDLKSEEGREVLR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 473 RLAEDADVVLTNFKPGVAQALGMDFGSLKKVNPGIVVVDSSAFGPTGPWARRLGYGPLVRAAAGFTDLWVYPDAPGEFCD 552
Cdd:pfam02515 80 RLVARADVVIENFRPGVLERLGLGYEDLRAINPRLIYCSVSGYGQTGPYADRPGYDLIAQAMSGLMSLTGEPGGPPVKVG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 553 TVTVypDHVAARIGALTALTLLLRRERTGTGGAVSVAQSEVMLSHLAGEIAA-----EVLQRQGHARSDEpvhdAPWGLF 627
Cdd:pfam02515 160 TPVG--DIVTGLLAAIAILAALLARERTGKGQVIDVSLLEAALALMGPQLLEylatgRVPGRVGNRHPAA----APYGLY 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 628 PAegEDKWVAVTVRDTTDWQALCGVIGRADLAADDALNTPAGRDADRARIDEAVRAWTSARTATAAMELLQKAGVPAGAV 707
Cdd:pfam02515 234 RT--ADGWVAIAAGTDKQWARLCRALGRPELADDPRFATNAARVQNRAELDAELAAWLATRTAAEWLALLAAAGVPAGPV 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 500047277 708 LHAGEVPNFGYYAERRAFREELHPHaAEPFMMENVQIHSDRVADPPLGQAPLLGEQT 764
Cdd:pfam02515 312 NTVEEVLDDPHLRARGMVVEVDHPD-YGPVPVPGLPVRLSGTPGRVRRPAPALGEHT 367
|
|
| CaiB |
COG1804 |
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid ... |
10-372 |
8.10e-49 |
|
Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases [Lipid transport and metabolism];
Pssm-ID: 441409 Cd Length: 397 Bit Score: 177.61 E-value: 8.10e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 10 PLSGVKVLDLSS---GPITavGRLLADLGAQVTPVNLAGVTEAGATVGPRIGAVPVG-TAINRFGLStVDLDTSTADGAR 85
Cdd:COG1804 6 PLAGIRVLDLSRvlaGPFA--TMLLADLGADVIKVERPGGGDPTRGWGPPFDGESAYfLSLNRNKRS-ITLDLKSPEGRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 86 RWRELLADADILIENTRPGSDAEKALSAREIHADHPSLVILSVSDFGRDTAYRTWQATTPVLHALTSELSRSGIPGREPL 165
Cdd:COG1804 83 LLRRLVARADVLVENFRPGVLERLGLGYEALRAINPRLIYCSISGFGQTGPYADRPGYDLIAQAMSGLMSLTGEPDGPPV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 166 VPPAPQlpyqvaaaqaAVMTVSVY---------LDRLRTGTGDLIDFSVLDGAMQTLDPPFGTpGTASAGVPlaEQRRNW 236
Cdd:COG1804 163 RVGVSV----------ADIAAGLYaaigilaalLHRERTGRGQVVDVSLLDAALALLANQAAE-YLATGEVP--ERTGNR 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 237 LAERQRYPIVRCKDGYVRICVLAKRQWQGMFTWMGEPEEFADPKFNSLMERFM-SPTLLPAIERFCADKTRAELEAEGQR 315
Cdd:COG1804 230 HPGIAPYGVYRTADGWVAIAAGNDRQWRRLCEALGRPDLADDPRFATNAARVAnRDELDALLAAWFATRTRAEWLELLEA 309
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 500047277 316 HGVPTAAVLTLTEALDTEQVKERGFFREVELANGFTAPVPVGVSEVDGHRASALTAP 372
Cdd:COG1804 310 AGVPAAPVNTLAEVLADPQLAARGMFVEVDHPDGGPVRQPGPPPRFSGTPGRVRRPA 366
|
|
| CoA_transf_3 |
pfam02515 |
CoA-transferase family III; CoA-transferases are found in organizms from all lines of descent. ... |
11-373 |
1.14e-44 |
|
CoA-transferase family III; CoA-transferases are found in organizms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.
Pssm-ID: 426810 [Multi-domain] Cd Length: 367 Bit Score: 165.09 E-value: 1.14e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 11 LSGVKVLDLSS---GPITAvgRLLADLGAQVTPVNLAGVTEA---GATVGPRIGAVPVGTAINRFGLStvdLDTSTADGA 84
Cdd:pfam02515 1 LAGIRVLDLTQvvaGPFAT--MLLADLGAEVIKVEPPGGDPTryvGPYAEKGGSAYFLSVNRNKRSVA---LDLKSEEGR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 85 RRWRELLADADILIENTRPGSDAEKALSAREIHADHPSLVILSVSDFGRDTAYRTWQATTPVLHALTSELSRSGIPGREP 164
Cdd:pfam02515 76 EVLRRLVARADVVIENFRPGVLERLGLGYEDLRAINPRLIYCSVSGYGQTGPYADRPGYDLIAQAMSGLMSLTGEPGGPP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 165 LVPPAPQLPYQVAAAQAAVMtVSVYLDRLRTGTGDLIDFSVLDGAMQTLDPPFG-TPGTASAGVPLAEQRRNWlaerQRY 243
Cdd:pfam02515 156 VKVGTPVGDIVTGLLAAIAI-LAALLARERTGKGQVIDVSLLEAALALMGPQLLeYLATGRVPGRVGNRHPAA----APY 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 244 PIVRCKDGYVRICVLAKRQWQGMFTWMGEPEEFADPKFNSLMERF-MSPTLLPAIERFCADKTRAELEAEGQRHGVPTAA 322
Cdd:pfam02515 231 GLYRTADGWVAIAAGTDKQWARLCRALGRPELADDPRFATNAARVqNRAELDAELAAWLATRTAAEWLALLAAAGVPAGP 310
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 500047277 323 VLTLTEALDTEQVKERGFFREVELANGFTAPV---PVGVSEVDGHRASAltAPR 373
Cdd:pfam02515 311 VNTVEEVLDDPHLRARGMVVEVDHPDYGPVPVpglPVRLSGTPGRVRRP--APA 362
|
|
| PRK05398 |
PRK05398 |
formyl-coenzyme A transferase; Provisional |
394-788 |
3.85e-34 |
|
formyl-coenzyme A transferase; Provisional
Pssm-ID: 180055 Cd Length: 416 Bit Score: 135.87 E-value: 3.85e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 394 GLPLEGLRVLDLGVIVVGADTGRLFADLGADVIKIENSAFPDGLRGRLNMMSQTYA----SGHRNKRSIGIDLRSDEGRA 469
Cdd:PRK05398 2 TKPLEGIKVLDFTHVQSGPSCTQLLAWFGADVIKVERPGVGDVTRNQLRDIPDVDSlyftMLNSNKRSITLDTKTPEGKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 470 LAHRLAEDADVVLTNFKPGVAQALGMDFGSLKKVNPGIVVVDSSAFGPTGPWARRLGYGPLVRAAAG---FTDLWvypDA 546
Cdd:PRK05398 82 VLEKLIREADVLVENFGPGALDRMGFTWERIQEINPRLIVASIKGFGPGSPYEDVKAYENVAQCAGGaasTTGFW---DG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 547 PgefcDTVTvypdhvAARIGAltaltlllrrerTGTGgavsvaqsevmlSHLAGEIAAEVLQRQGHARS---DEPVHDA- 622
Cdd:PRK05398 159 P----PTVS------GAALGD------------SNTG------------MHLAIGILAALLQREKTGRGqrvTVSMQDAv 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 623 ------------------PWGLFPAEGEDKW--------------------------------VAVTVRDTTdWQALCGV 652
Cdd:PRK05398 205 lnlcrvklrdqqrldhlgYLEEYPQYPNGTFgdavpragnasgggqpgwilkckgwetdpnayIYFIIQPQG-WEPICKA 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 653 IGRADLAADDALNTPAGRDADRARIDEAVRAWTSARTATAAMELLQKAGVPAGAVLHAGEVPNFGYYAERRAFREELHPH 732
Cdd:PRK05398 284 IGKPEWITDPAYATPEARQPHLFDIFAEIEKWTMTKTKFEAVDILNAFDIPCGPVLSMKEIAEDPSLRASGTIVEVDHPL 363
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 500047277 733 AAE------PFMMENVQihsdrvadPPLGQAPLLGEQTREIAAElLGLSDAEIDELIERGVL 788
Cdd:PRK05398 364 RGKyltvgsPIKLSDSP--------PDVKRSPLLGEHTDEVLAE-LGYSDDQIAALKQNGAI 416
|
|
| PRK11430 |
PRK11430 |
putative CoA-transferase; Provisional |
396-771 |
1.98e-32 |
|
putative CoA-transferase; Provisional
Pssm-ID: 183132 [Multi-domain] Cd Length: 381 Bit Score: 130.10 E-value: 1.98e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 396 PLEGLRVLDLGVIVVGADTGRLFADLGADVIKIENSAFPDGLRG---RLNMMSQTYASGHRNKRSIGIDLRSDEGRALAH 472
Cdd:PRK11430 9 PFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPPGHGDDTRTfgpYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFI 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 473 RLAEDADVVLTNFKPGVAQALGMDFGSLKKVNPGIVVVDSSAFGPTGPWARRLGYGPLVRAAAGFTDLWVYPDAP----- 547
Cdd:PRK11430 89 NMLKQADVLAENFRPGTMEKLGFSWETLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPDAPpvrvg 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 548 ---GEFCDTVTVYPDHVAARIGaltaltlllrRERTGTGGAVSVAQSEVMLSHLAGEIAAEVLQRQGHAR-SDEPVHDAP 623
Cdd:PRK11430 169 tslADLCGGVYLFSGIVSALYG----------REKSQRGAHVDIAMFDATLSFLEHGLMAYIATGKSPQRlGNRHPYMAP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 624 WGLFPAegEDKWVAVTVRDTTDWQALCGVIGRADLAADDALNTPAGRDADRARIDEAVRAWTSARTATAAMELLQKAGVP 703
Cdd:PRK11430 239 FDVFDT--QDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVP 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 500047277 704 AGAVLHAGEVPNFGYYAERRAFREelhphaAEPFMMENVQIHSDRVADP-PLGQAPLLGEQTREIAAEL 771
Cdd:PRK11430 317 VAPLLSVAEAINLPQTQARNMLIE------AGGIMMPGNPIKISGCADPhVMPGAATLDQHGEQIRQEF 379
|
|
| PRK03525 |
PRK03525 |
L-carnitine CoA-transferase; |
396-787 |
2.67e-16 |
|
L-carnitine CoA-transferase;
Pssm-ID: 179589 Cd Length: 405 Bit Score: 81.73 E-value: 2.67e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 396 PLEGLRVLDLGVIVVGADTGRLFADLGADVIKIENSAFPDGLRgrlnmmSQTYAS--GHRNKRSIGIDLRSDEGRALAHR 473
Cdd:PRK03525 11 PLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIR------VQPNYPqlSRRNLHALSLNIFKDEGREAFLK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 474 LAEDADVVLTNFKPGVAQALGMDFGSLKKVNPGIVVVDSSAFGPTG--PWARRLGYGPLVRAAAGFTDLWVYPDAP---- 547
Cdd:PRK03525 85 LMETTDIFIEASKGPAFARRGITDEVLWEHNPKLVIAHLSGFGQYGteEYTNLPAYNTIAQAFSGYLIQNGDVDQPmpaf 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 548 ---GEFCDTVTVYPDHVAArigaltaltlLLRRERTGTGGAVSVAQSEVML--------SHLAGeiaAEVLQRQGHARSD 616
Cdd:PRK03525 165 pytADYFSGLTATTAALAA----------LHKARETGKGESIDIAMYEVMLrmgqyfmmDYFNG---GEMCPRMTKGKDP 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 617 epvHDAPWGLFPAegEDKWVAVTVRDTTDWQALCGVIGRADLAADD----------ALNTPAGRdadraRIDEAVRAWTS 686
Cdd:PRK03525 232 ---YYAGCGLYKC--ADGYIVMELVGITQIKECFKDIGLAHLLGTPeipegtqlihRIECPYGP-----LVEEKLDAWLA 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 687 ARTATAAMELLQKAGVPAGAVLHAGEVPNFGYYAERRAFREELHPHAAE---PFMMENVQIHSDRVADPplgqAPLLGEQ 763
Cdd:PRK03525 302 AHTIAEVEARFAELNIACAKVLTIPELESNPQYVARESITQWQTMDGRTckgPNIMPKFKNNPGQIWRG----MPSHGMD 377
|
410 420
....*....|....*....|....
gi 500047277 764 TREIAAElLGLSDAEIDELIERGV 787
Cdd:PRK03525 378 TAAILKN-IGYSEEDIQELVAKGL 400
|
|
| PRK11430 |
PRK11430 |
putative CoA-transferase; Provisional |
10-362 |
6.75e-16 |
|
putative CoA-transferase; Provisional
Pssm-ID: 183132 [Multi-domain] Cd Length: 381 Bit Score: 80.41 E-value: 6.75e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 10 PLSGVKVLDLS---SGPITAvgRLLADLGAQVTPVNLAGVTEAGATVGPRIGAVPVGTAINRFGLSTVDLDTSTADGARR 86
Cdd:PRK11430 9 PFEGLLVIDMThvlNGPFGT--QLLCNMGARVIKVEPPGHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 87 WRELLADADILIENTRPGSDAEKALSAREIHADHPSLVILSVSDFGRDTAYRTWQATTPVLHALTSELSRSGIPGREPlV 166
Cdd:PRK11430 87 FINMLKQADVLAENFRPGTMEKLGFSWETLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYPDAPP-V 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 167 PPAPQLPYQVAAAQAAVMTVSVYLDRLRTGTGDLIDFSVLDGAMQTLDPPFgtpgTASAGVPLAEQRrnwLAERQRY--- 243
Cdd:PRK11430 166 RVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGL----MAYIATGKSPQR---LGNRHPYmap 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 244 -PIVRCKDGYVRICVLAKRQWQGMFTWMGEPEEFADPKFNSLMERFMSPTLLPA-IERFCADKTRAELEAEGQRHGVPTA 321
Cdd:PRK11430 239 fDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPRFSSNILRVQNQAILKQyIERTLKTQAAEVWLARIHEVGVPVA 318
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 500047277 322 AVLTLTEALDTEQVKERGFFREvelANGFTAP-VPVGVSEVD 362
Cdd:PRK11430 319 PLLSVAEAINLPQTQARNMLIE---AGGIMMPgNPIKISGCA 357
|
|
| PRK05398 |
PRK05398 |
formyl-coenzyme A transferase; Provisional |
10-345 |
3.38e-14 |
|
formyl-coenzyme A transferase; Provisional
Pssm-ID: 180055 Cd Length: 416 Bit Score: 75.39 E-value: 3.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 10 PLSGVKVLDLS---SGPitAVGRLLADLGAQVTPVNLAGVTEAgaTVG-----PRIGAVPVgTAINRFGLStVDLDTSTA 81
Cdd:PRK05398 4 PLEGIKVLDFThvqSGP--SCTQLLAWFGADVIKVERPGVGDV--TRNqlrdiPDVDSLYF-TMLNSNKRS-ITLDTKTP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 82 DGARRWRELLADADILIENTRPGSDAEKALSAREIHADHPSLVILSVSDFGRDTAYRTWQATTPVLHALTSELSRSGIPG 161
Cdd:PRK05398 78 EGKEVLEKLIREADVLVENFGPGALDRMGFTWERIQEINPRLIVASIKGFGPGSPYEDVKAYENVAQCAGGAASTTGFWD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 162 REPLVPPApQLPYQVAAAQAAVMTVSVYLDRLRTGTGDLIDFSVLDGAM----------QTLD-------------PPFG 218
Cdd:PRK05398 158 GPPTVSGA-ALGDSNTGMHLAIGILAALLQREKTGRGQRVTVSMQDAVLnlcrvklrdqQRLDhlgyleeypqypnGTFG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 219 --TP--GTASAGvplaeQRRNWlaerqrypIVRCK------DGYVRICVLAKrQWQGMFTWMGEPEEFADPKFNS----- 283
Cdd:PRK05398 237 daVPraGNASGG-----GQPGW--------ILKCKgwetdpNAYIYFIIQPQ-GWEPICKAIGKPEWITDPAYATpearq 302
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 500047277 284 --LMERFmsptllPAIERFCADKTRAELEAEGQRHGVPTAAVLTLTEALDTEQVKERGFFREVE 345
Cdd:PRK05398 303 phLFDIF------AEIEKWTMTKTKFEAVDILNAFDIPCGPVLSMKEIAEDPSLRASGTIVEVD 360
|
|
| PRK03525 |
PRK03525 |
L-carnitine CoA-transferase; |
1-351 |
2.91e-11 |
|
L-carnitine CoA-transferase;
Pssm-ID: 179589 Cd Length: 405 Bit Score: 66.32 E-value: 2.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 1 MTSTDTYDPpLSGVKVLdLSSGPITA--VGRLLADLGAQVTPV-NLAGvteagatvGPRIGAVPVGTAINRFGLSTVDLD 77
Cdd:PRK03525 3 HLPMPKFGP-LAGLRVV-FSGIEIAGpfAGQMFAEWGAEVIWIeNVAW--------ADTIRVQPNYPQLSRRNLHALSLN 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 78 TSTADGARRWRELLADADILIENTRPGSDAEKALSAREIHADHPSLVILSVSDFGR--DTAYRTWQATTPVLHALTSELS 155
Cdd:PRK03525 73 IFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWEHNPKLVIAHLSGFGQygTEEYTNLPAYNTIAQAFSGYLI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 156 RSGIPGReplvpPAPQLPYQVAAAQAAVMTVSVY--LDRLR-TGTGDLIDFSVLD-----GAMQTLDppfgtpgTASAGV 227
Cdd:PRK03525 153 QNGDVDQ-----PMPAFPYTADYFSGLTATTAALaaLHKAReTGKGESIDIAMYEvmlrmGQYFMMD-------YFNGGE 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 228 P---LAEQRRNWLAERQRYpivRCKDGYVRICVLAKRQWQGMFTWMG-----EPEEFadPKFNSLMERFMSP---TLLPA 296
Cdd:PRK03525 221 McprMTKGKDPYYAGCGLY---KCADGYIVMELVGITQIKECFKDIGlahllGTPEI--PEGTQLIHRIECPygpLVEEK 295
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 500047277 297 IERFCADKTRAELEAEGQRHGVPTAAVLTLTEALDTEQVKERGFFREVELANGFT 351
Cdd:PRK03525 296 LDAWLAAHTIAEVEARFAELNIACAKVLTIPELESNPQYVARESITQWQTMDGRT 350
|
|
| mesacon_CoA_iso |
TIGR04253 |
mesaconyl-CoA isomerase; Members of this protein family belong by homology to the family of ... |
397-791 |
3.43e-11 |
|
mesaconyl-CoA isomerase; Members of this protein family belong by homology to the family of CoA transferases. However, the characterized member from Chloroflexus aurantiacus appears to perform an intramolecular transfer, making it an isomerase. The enzyme converts mesaconyl-C1-CoA to mesaconyl-C4-CoA as part of the bicyclic 3-hydroxyproprionate pathway for carbon fixation.
Pssm-ID: 211976 Cd Length: 403 Bit Score: 66.14 E-value: 3.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 397 LEGLRVLDLGVIVVGADTGRLFADLGADVIK-------IENSAFPDGLRGRLNMMsqtYASGHRNKRSIGIDLRSDEGRA 469
Cdd:TIGR04253 3 LHGLRVVEGSAFVAAPLGGMTLAQLGADVIRfdpigggLDYKRWPLTLDGKHSLF---WAGLNKGKRSIAIDIRHPRGQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 470 LAHRL----AEDADVVLTNFKpgvaqALG-MDFGSLKKVNPGIVVVDSSAfgptgpwaRRLGYGPL---VRAAAGFTdLW 541
Cdd:TIGR04253 80 LLTQLicapGDHAGLFITNFP-----AKGwLAYDALKAHRADLIMVNLTG--------RRDGGSEVdytLNPQLGLP-FM 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 542 VYPDAPGEFCDTVTVYPDHVAARIGALTALTLLLRRERTGTGGAVSVAQSEV---MLSHLAgeIAAEVL------QRQGH 612
Cdd:TIGR04253 146 TGPTSSPDVVNHVFPAWDFISGQMIALGLLAAERHRRLTGEGQLVKIALKDValaMIGHFG--MIAEAMindadrPRQGN 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 613 ArsdepvhdapwgLFPAEGED------KWVAVTVRDTTDWQALCGVIGRAD----LAADDALNTPAGRDADRAR--IDEA 680
Cdd:TIGR04253 224 Y------------LYGAFGRDfetldgKRLMVVGLTDLQWKALGKATGLRDafnaLAARLGLDFDDEGDRFRARheIAAL 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 681 VRAWTSARTATAAMELLQKAGVPagavlhagevpnfgyYAERRAFREELhphAAEP-------------------FMMEN 741
Cdd:TIGR04253 292 FEPWFHARTLAEAALIFDAHGVT---------------WAPYRSVREAI---AADPdcstdnpmfalteqpgigrYLMPG 353
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 500047277 742 VQIHSDRVADPPLGQAPLLGEQTREIAAELLGLSDAEIDELIERGVLEMP 791
Cdd:TIGR04253 354 SPLDFAAVPRLPAMPAPRLGEHTDEILLDILGLSEAEVGRLHDAGIVAGP 403
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
517-799 |
1.34e-03 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 42.55 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 517 PTGPWARRLGYGPLVRAAAGFTDLWVYPDAPGEFCDTVTVYPDHVAARIGALTALTLLLRRERTGTGGAVSVAQSEVMLS 596
Cdd:COG3321 864 PTYPFQREDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALL 943
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 597 HLAGEIAAEVLQRQGHARSDEPVHDAPWGLFPAEGEDKWVAVTVRDTTDWQALCGVIGRADLAADDALNTPAGRDADRAR 676
Cdd:COG3321 944 ALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLA 1023
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500047277 677 IDEAVRAWTSARTATAAMELLQKAGVPAGAVLHAGEVPNFGY-YAERRAFREELHPHAAEPFMMENVQIHSDRVADPPLG 755
Cdd:COG3321 1024 LAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALaALLLLAALAELALAAAALALAAALAAAALALALAALA 1103
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 500047277 756 QAPLLGEQTREIAAELLGLSDAEIDELIERGVLEMPQEVTAAQR 799
Cdd:COG3321 1104 AALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAA 1147
|
|
| |
