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Conserved domains on  [gi|500071484|ref|WP_011747497|]
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molybdopterin-binding protein [Paracoccus denitrificans]

Protein Classification

TOBE domain-containing protein( domain architecture ID 10007583)

TOBE (Transport-associated OB) domain-containing protein is also known as molybdopterin-binding protein that may be involved in the recognition of small ligands such as molybdenum and sulfate

CATH:  2.40.50.100
Gene Ontology:  GO:0015689
PubMed:  8458342
SCOP:  4000175

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MopI COG3585
Molybdopterin-binding protein MopI [Coenzyme transport and metabolism];
1-69 9.10e-20

Molybdopterin-binding protein MopI [Coenzyme transport and metabolism];


:

Pssm-ID: 442804 [Multi-domain]  Cd Length: 141  Bit Score: 76.27  E-value: 9.10e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500071484   1 MRLSARNVLPGTVTEIVTGAVTSHVRIDLG-GSVVTASITNDAVKELGLAVGGRASAVVKASDVMVGVDD 69
Cdd:COG3585   72 MKLSARNQLKGTVTRIERGAVNSEVVLDLGgGTTLTAVITNESVEELGLKEGDEVTALFKASSVILAVDA 141
 
Name Accession Description Interval E-value
MopI COG3585
Molybdopterin-binding protein MopI [Coenzyme transport and metabolism];
1-69 9.10e-20

Molybdopterin-binding protein MopI [Coenzyme transport and metabolism];


Pssm-ID: 442804 [Multi-domain]  Cd Length: 141  Bit Score: 76.27  E-value: 9.10e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500071484   1 MRLSARNVLPGTVTEIVTGAVTSHVRIDLG-GSVVTASITNDAVKELGLAVGGRASAVVKASDVMVGVDD 69
Cdd:COG3585   72 MKLSARNQLKGTVTRIERGAVNSEVVLDLGgGTTLTAVITNESVEELGLKEGDEVTALFKASSVILAVDA 141
Mop TIGR00638
molybdenum-pterin binding domain; This model describes a multigene family of molybdenum-pterin ...
 1-68 2.83e-17

molybdenum-pterin binding domain; This model describes a multigene family of molybdenum-pterin binding proteins of about 70 amino acids in Clostridium pasteurianum, as a tandemly-repeated domain C-terminal to an unrelated domain in ModE, a molybdate transport gene repressor of E. coli, and in single or tandemly paired domains in several related proteins. [Transport and binding proteins, Anions]


Pssm-ID: 273189 [Multi-domain]  Cd Length: 69  Bit Score: 68.15  E-value: 2.83e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 500071484   1 MRLSARNVLPGTVTEIVTGAVTSHVRIDLGG-SVVTASITNDAVKELGLAVGGRASAVVKASDVMVGVD 68
Cdd:TIGR00638  1 LQTSARNQLKGKVVAIEDGDVNAEVDLLLGGgTKLTAVITLESVAELGLKPGKEVYAVIKAPWVILAVD 69
TOBE pfam03459
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the ...
 5-63 4.00e-09

TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the C-terminal strand of each domain is supplied by the partner. Probably involved in the recognition of small ligands such as molybdenum and sulfate. Found in ABC transporters immediately after the ATPase domain.


Pssm-ID: 427310 [Multi-domain]  Cd Length: 60  Bit Score: 47.27  E-value: 4.00e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 500071484   5 ARNVLPGTVTEIVTGAVTSHVRIDLGGS-VVTASITNDAVKELGLAVGGRASAVVKASDV 63
Cdd:pfam03459  1 ARNQLPGTVTVIEPLGSEVEVRVDLGGGlTLTARITRDSAEELGLAPGDEVWALIKATKV 60
PRK10676 PRK10676
DNA-binding transcriptional regulator ModE; Provisional
 4-65 1.17e-06

DNA-binding transcriptional regulator ModE; Provisional


Pssm-ID: 182640 [Multi-domain]  Cd Length: 263  Bit Score: 43.49  E-value: 1.17e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 500071484   4 SARNVLPGTVTEIVTGAVTSHVRIDL-GGSVVTASITNDAVKELGLAVGGRASAVVKASDVMV 65
Cdd:PRK10676 197 AADNQLPGTISHIERGAEQSEVLMALpDGQTLCATVPNNEAARLSLQQGDAVTAYFNADRVII 259
 
Name Accession Description Interval E-value
MopI COG3585
Molybdopterin-binding protein MopI [Coenzyme transport and metabolism];
1-69 9.10e-20

Molybdopterin-binding protein MopI [Coenzyme transport and metabolism];


Pssm-ID: 442804 [Multi-domain]  Cd Length: 141  Bit Score: 76.27  E-value: 9.10e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500071484   1 MRLSARNVLPGTVTEIVTGAVTSHVRIDLG-GSVVTASITNDAVKELGLAVGGRASAVVKASDVMVGVDD 69
Cdd:COG3585   72 MKLSARNQLKGTVTRIERGAVNSEVVLDLGgGTTLTAVITNESVEELGLKEGDEVTALFKASSVILAVDA 141
Mop TIGR00638
molybdenum-pterin binding domain; This model describes a multigene family of molybdenum-pterin ...
 1-68 2.83e-17

molybdenum-pterin binding domain; This model describes a multigene family of molybdenum-pterin binding proteins of about 70 amino acids in Clostridium pasteurianum, as a tandemly-repeated domain C-terminal to an unrelated domain in ModE, a molybdate transport gene repressor of E. coli, and in single or tandemly paired domains in several related proteins. [Transport and binding proteins, Anions]


Pssm-ID: 273189 [Multi-domain]  Cd Length: 69  Bit Score: 68.15  E-value: 2.83e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 500071484   1 MRLSARNVLPGTVTEIVTGAVTSHVRIDLGG-SVVTASITNDAVKELGLAVGGRASAVVKASDVMVGVD 68
Cdd:TIGR00638  1 LQTSARNQLKGKVVAIEDGDVNAEVDLLLGGgTKLTAVITLESVAELGLKPGKEVYAVIKAPWVILAVD 69
TOBE pfam03459
TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the ...
 5-63 4.00e-09

TOBE domain; The TOBE domain (Transport-associated OB) always occurs as a dimer as the C-terminal strand of each domain is supplied by the partner. Probably involved in the recognition of small ligands such as molybdenum and sulfate. Found in ABC transporters immediately after the ATPase domain.


Pssm-ID: 427310 [Multi-domain]  Cd Length: 60  Bit Score: 47.27  E-value: 4.00e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 500071484   5 ARNVLPGTVTEIVTGAVTSHVRIDLGGS-VVTASITNDAVKELGLAVGGRASAVVKASDV 63
Cdd:pfam03459  1 ARNQLPGTVTVIEPLGSEVEVRVDLGGGlTLTARITRDSAEELGLAPGDEVWALIKATKV 60
PRK10676 PRK10676
DNA-binding transcriptional regulator ModE; Provisional
 4-65 1.17e-06

DNA-binding transcriptional regulator ModE; Provisional


Pssm-ID: 182640 [Multi-domain]  Cd Length: 263  Bit Score: 43.49  E-value: 1.17e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 500071484   4 SARNVLPGTVTEIVTGAVTSHVRIDL-GGSVVTASITNDAVKELGLAVGGRASAVVKASDVMV 65
Cdd:PRK10676 197 AADNQLPGTISHIERGAEQSEVLMALpDGQTLCATVPNNEAARLSLQQGDAVTAYFNADRVII 259
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
4-64 2.45e-06

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 42.55  E-value: 2.45e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 500071484   4 SARNVLPGTVTEI--VTGAVTshVRIDLGGSVVTASITNDAVKELGLAVGGRASAVVKASDVM 64
Cdd:PRK11144 291 SIRNILRAKVVEIydDNGQVE--VKLEVGGKTLWARITPWARDELALKPGQWLYAQIKSVSIT 351
PRK10676 PRK10676
DNA-binding transcriptional regulator ModE; Provisional
 4-65 2.99e-04

DNA-binding transcriptional regulator ModE; Provisional


Pssm-ID: 182640 [Multi-domain]  Cd Length: 263  Bit Score: 36.55  E-value: 2.99e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 500071484   4 SARNVLPGTVTEIVTGAVTSHVRIDL--GGSVVTASITNDAVKELGLAVGGRASAVVKASDVMV 65
Cdd:PRK10676 125 SARNQWFGTITARDHQQVQQHVDVLLadGKTRLKVAITAQSAERLGLDEGKEVLVLIKAPWVGI 188
MopI COG3585
Molybdopterin-binding protein MopI [Coenzyme transport and metabolism];
1-69 2.25e-03

Molybdopterin-binding protein MopI [Coenzyme transport and metabolism];


Pssm-ID: 442804 [Multi-domain]  Cd Length: 141  Bit Score: 33.90  E-value: 2.25e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500071484   1 MRLSARNVLPGTVTEIVTGAVTSHVRIDL-GGSVVTASITNDAVKELGLAVGGRASAVVKASDVMVGVDD 69
Cdd:COG3585    1 MTSSRNNQFGGVVSIIAGGVVNEVVLLLLgGGTIIAAITTASSAELLGLVGGKEVAALKKASVVILATDD 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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