|
Name |
Accession |
Description |
Interval |
E-value |
| yebU |
PRK11933 |
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed |
1-465 |
0e+00 |
|
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed
Pssm-ID: 183387 [Multi-domain] Cd Length: 470 Bit Score: 886.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 1 MVQLNQKFINSIAQEMPPHLSMDDFVHYCGLPLRLSIRVNTLKITSDALRAILEPRGWQFEPVPWCEDGFWVTVPDD--C 78
Cdd:PRK11933 1 MVYLPDAFLTQMREAMPSHLSMDDFIAACQRPLRRSIRVNTLKISVADFLQLMAPYGWTLTPIPWCEEGFWIERDDEdaL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 79 QPGNLTEHYQGLFYIQEASSMMPPCALFMDKEPRQLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQR 158
Cdd:PRK11933 81 PLGNTAEHLSGLFYIQEASSMLPVAALFADDNAPQRVLDMAAAPGSKTTQIAALMNNQGAIVANEYSASRVKVLHANISR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 159 MGVANVAITQFDGRVFGAHLYETLDAIQLDAPCSGEGTVRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVY 238
Cdd:PRK11933 161 CGVSNVALTHFDGRVFGAALPETFDAILLDAPCSGEGTVRKDPDALKNWSPESNLEIAATQRELIESAFHALKPGGTLVY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 239 STCTLNRRENEDVCHFLKERYGDAVVFESLNDLFKGADKALTEEGFLHIWPQIYDSEGFFVARIRKTASVARNTDDPRFV 318
Cdd:PRK11933 241 STCTLNREENQAVCLWLKETYPDAVEFEPLGDLFPGAEKALTEEGFLHVFPQIYDSEGFFVARLRKTASVPRLPAPKYKV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 319 SKFPFVAANRKELSALEEAMLALGVSLPEDAVIVTRDGEFWLMPAPLDGLLTKMRFQRIGIRLAETQKHGIKVRHEAVMA 398
Cdd:PRK11933 321 GKFPFTPAKDKEAQEIRQAAASVGLSWPENLRLWQRDKEVWLFPAGIEPLIGKVRFSRIGIKLAETHKKGYRWQHEAVIA 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 399 LPC---NQMLSIEPEAAKQYLMGRDIALDNAgKAQGEKILSLHGAPLGIAKHLGNKLKNSLPRDLCRDNV 465
Cdd:PRK11933 401 LASpdnANAFELTPQEAEEWYMGRDIYPQTA-PPAGEVIVTYQGQPIGLAKRVGNRLKNSLPRELVRDGK 469
|
|
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
37-304 |
1.10e-112 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 332.89 E-value: 1.10e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 37 IRVNTLKITSDALRAILEPRGWQFEPvpWCEDGFWVTVPDDCQPGNLTEHYQGLFYIQEASSMMPPCALFMDkePRQLLL 116
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVLEP--TCEEYFFEVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPR--EDERVL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 117 DVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDGRVFGAHLYEtLDAIQLDAPCSGEGT 196
Cdd:TIGR00446 77 DMAAAPGGKTTQISQLMKNKGCIVANEISKSRTKALISNINRMGVLNTIVINADGRKFGAYLLK-FDAILLDAPCSGEGV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 197 VRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDVCHFLKERYGDAVVFESLNDLFKGAD 276
Cdd:TIGR00446 156 IRKDPSRKRNWSEEDIKYCSLLQKELIDAAIDALKPGGVLVYSTCSLEVEENEEVIDYILRKRPDVVEEIIKGDEFFGIN 235
|
250 260
....*....|....*....|....*....
gi 500084139 277 KAL-TEEGFLHIWPQIYDSEGFFVARIRK 304
Cdd:TIGR00446 236 IGKgEVKGALRVFPQNYDCEGFFVAKLRK 264
|
|
| RsmB |
COG0144 |
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and ... |
32-306 |
9.55e-88 |
|
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 439914 [Multi-domain] Cd Length: 441 Bit Score: 274.96 E-value: 9.55e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 32 PLRLSIRVNTLKITSDALRAILEPRGWQFEPVPWCEDGFWVTVPddCQPGNLTEHYQGLFYIQEASSMMPpcALFMDKEP 111
Cdd:COG0144 174 PPPLDLRVNTLKASREELLARLAEEGIEAEPTPLSPDGLRLEGP--GPVTALPGFREGLFSVQDEASQLV--ALLLDPKP 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 112 RQLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDGRVFGAHLYETLDAIQLDAPC 191
Cdd:COG0144 250 GERVLDLCAAPGGKTLHLAELMGNKGRVVAVDISEHRLKRLRENLARLGLSNVEVVVADARELLEWLPGKFDRVLLDAPC 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 192 SGEGTVRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDVCHFLKERYGDAVVfESLNDL 271
Cdd:COG0144 330 SGTGTLRRHPDIKWRRTPEDIAELAALQRELLDAAARLLKPGGRLVYSTCSLLPEENEEVVEAFLARHPDFEL-VPLAEL 408
|
250 260 270
....*....|....*....|....*....|....*
gi 500084139 272 FkgADKALTEEGFLHIWPQIYDSEGFFVARIRKTA 306
Cdd:COG0144 409 L--PGLALTDGGYLRLLPHRHGTDGFFIARLRKKA 441
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
104-303 |
3.00e-50 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 169.53 E-value: 3.00e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 104 ALFMDKEPRQLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDGRVFGAHLYETL- 182
Cdd:pfam01189 1 AILLAPQEGETILDMCAAPGGKTTHIAELMKNQGTVVAVDINKHRLKRVAENIHRLGVTNTIILNGDGRQPDQWLGGVLf 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 183 DAIQLDAPCSGEGTVRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDVC-HFLKERygD 261
Cdd:pfam01189 81 DRILLDAPCSGTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLLKPGGVLVYSTCSVLPEENEAVIeYFLQKH--P 158
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 500084139 262 AVVFESLNdLFKGADKALTEEGFLHIWPQIYDSEGFFVARIR 303
Cdd:pfam01189 159 DVELVPTP-LFEPVGLAIGEQPTLRLLPHTHNGDGFFIAKLR 199
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| yebU |
PRK11933 |
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed |
1-465 |
0e+00 |
|
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed
Pssm-ID: 183387 [Multi-domain] Cd Length: 470 Bit Score: 886.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 1 MVQLNQKFINSIAQEMPPHLSMDDFVHYCGLPLRLSIRVNTLKITSDALRAILEPRGWQFEPVPWCEDGFWVTVPDD--C 78
Cdd:PRK11933 1 MVYLPDAFLTQMREAMPSHLSMDDFIAACQRPLRRSIRVNTLKISVADFLQLMAPYGWTLTPIPWCEEGFWIERDDEdaL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 79 QPGNLTEHYQGLFYIQEASSMMPPCALFMDKEPRQLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQR 158
Cdd:PRK11933 81 PLGNTAEHLSGLFYIQEASSMLPVAALFADDNAPQRVLDMAAAPGSKTTQIAALMNNQGAIVANEYSASRVKVLHANISR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 159 MGVANVAITQFDGRVFGAHLYETLDAIQLDAPCSGEGTVRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVY 238
Cdd:PRK11933 161 CGVSNVALTHFDGRVFGAALPETFDAILLDAPCSGEGTVRKDPDALKNWSPESNLEIAATQRELIESAFHALKPGGTLVY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 239 STCTLNRRENEDVCHFLKERYGDAVVFESLNDLFKGADKALTEEGFLHIWPQIYDSEGFFVARIRKTASVARNTDDPRFV 318
Cdd:PRK11933 241 STCTLNREENQAVCLWLKETYPDAVEFEPLGDLFPGAEKALTEEGFLHVFPQIYDSEGFFVARLRKTASVPRLPAPKYKV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 319 SKFPFVAANRKELSALEEAMLALGVSLPEDAVIVTRDGEFWLMPAPLDGLLTKMRFQRIGIRLAETQKHGIKVRHEAVMA 398
Cdd:PRK11933 321 GKFPFTPAKDKEAQEIRQAAASVGLSWPENLRLWQRDKEVWLFPAGIEPLIGKVRFSRIGIKLAETHKKGYRWQHEAVIA 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 399 LPC---NQMLSIEPEAAKQYLMGRDIALDNAgKAQGEKILSLHGAPLGIAKHLGNKLKNSLPRDLCRDNV 465
Cdd:PRK11933 401 LASpdnANAFELTPQEAEEWYMGRDIYPQTA-PPAGEVIVTYQGQPIGLAKRVGNRLKNSLPRELVRDGK 469
|
|
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
37-304 |
1.10e-112 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 332.89 E-value: 1.10e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 37 IRVNTLKITSDALRAILEPRGWQFEPvpWCEDGFWVTVPDDCQPGNLTEHYQGLFYIQEASSMMPPCALFMDkePRQLLL 116
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVLEP--TCEEYFFEVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPR--EDERVL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 117 DVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDGRVFGAHLYEtLDAIQLDAPCSGEGT 196
Cdd:TIGR00446 77 DMAAAPGGKTTQISQLMKNKGCIVANEISKSRTKALISNINRMGVLNTIVINADGRKFGAYLLK-FDAILLDAPCSGEGV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 197 VRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDVCHFLKERYGDAVVFESLNDLFKGAD 276
Cdd:TIGR00446 156 IRKDPSRKRNWSEEDIKYCSLLQKELIDAAIDALKPGGVLVYSTCSLEVEENEEVIDYILRKRPDVVEEIIKGDEFFGIN 235
|
250 260
....*....|....*....|....*....
gi 500084139 277 KAL-TEEGFLHIWPQIYDSEGFFVARIRK 304
Cdd:TIGR00446 236 IGKgEVKGALRVFPQNYDCEGFFVAKLRK 264
|
|
| RsmB |
COG0144 |
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and ... |
32-306 |
9.55e-88 |
|
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 439914 [Multi-domain] Cd Length: 441 Bit Score: 274.96 E-value: 9.55e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 32 PLRLSIRVNTLKITSDALRAILEPRGWQFEPVPWCEDGFWVTVPddCQPGNLTEHYQGLFYIQEASSMMPpcALFMDKEP 111
Cdd:COG0144 174 PPPLDLRVNTLKASREELLARLAEEGIEAEPTPLSPDGLRLEGP--GPVTALPGFREGLFSVQDEASQLV--ALLLDPKP 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 112 RQLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDGRVFGAHLYETLDAIQLDAPC 191
Cdd:COG0144 250 GERVLDLCAAPGGKTLHLAELMGNKGRVVAVDISEHRLKRLRENLARLGLSNVEVVVADARELLEWLPGKFDRVLLDAPC 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 192 SGEGTVRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDVCHFLKERYGDAVVfESLNDL 271
Cdd:COG0144 330 SGTGTLRRHPDIKWRRTPEDIAELAALQRELLDAAARLLKPGGRLVYSTCSLLPEENEEVVEAFLARHPDFEL-VPLAEL 408
|
250 260 270
....*....|....*....|....*....|....*
gi 500084139 272 FkgADKALTEEGFLHIWPQIYDSEGFFVARIRKTA 306
Cdd:COG0144 409 L--PGLALTDGGYLRLLPHRHGTDGFFIARLRKKA 441
|
|
| Ncl1 |
COG3270 |
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and ... |
14-460 |
3.67e-75 |
|
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442501 [Multi-domain] Cd Length: 452 Bit Score: 243.07 E-value: 3.67e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 14 QEMPPHLSMDDFVHYCGL-PLRLSIRVNTLKITSDALRAILEPRGWQFEPVPWCEDGFWVTVPDDCQPGNL-TEHYQGLF 91
Cdd:COG3270 9 QLMMLLLLEEEAAFAAALrLLRRSSLRVLLLKAAEDLALRLLAPPPLLPPPPWPEGGGYEEDEELGGPLGLaAAALYYLQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 92 YIQEASSMMPPCALFMDKEPRQLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDG 171
Cdd:COG3270 89 EAAAASSALPVAALPGLLLLLAAAAGGAAATAAAAAQGGLLLNLLNIILALELLASSVEVLHANIVVVVNTNTPLAELAG 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 172 RVFGAHLYETLDAIQLDAPCSGEGTVRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDV 251
Cdd:COG3270 169 FVFFDALDADADASLLGGGFPREGAAAKEADPLRKASAEIQLEIEAAAAAALLLGGGALLLTTTTEPSEEEEEEEELLLL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 252 CHFLKERYGDAVVFESLNDLFKGADKALTEEGFLHIWPQIYDSEGFFVARIRKTASVARNTDDPRFVSKFPfvaanrkEL 331
Cdd:COG3270 249 LEELDLALEPAVEEGAGEGGDPEAAAALTELLGLHRFPPHGEGGGGFFAALKKKAGDEPSPKKKKKKKKPK-------QA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 332 SALEEAMLALGVSLPEDAVIVTRDGEFWLMPAPLDgLLTKMRFQRIGIRLAETQKHGIKVRHEAVMALPCNQM---LSIE 408
Cdd:COG3270 322 KEVLRAFAEEGLPLPEVGRLWERGGKLYLLPEELP-DLSGLKVLRIGLKLGEIKKKRFEPSHALALALGPEATknvVELD 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 500084139 409 PEAAKQYLMGRDIALDNAGKaqGEKILSLHGAPLGIAKHLGNKLKNSLPRDL 460
Cdd:COG3270 401 AEEALRYLKGEDIELEDGDK--GWVLVTYDGYPLGWGKYVGGRLKNHYPKGL 450
|
|
| PRK14902 |
PRK14902 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
36-304 |
6.00e-69 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 237857 [Multi-domain] Cd Length: 444 Bit Score: 226.21 E-value: 6.00e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 36 SIRVNTLKITSDALRAILEPRGWQFEPVPWCEDGFWVTvpddcqPGNL--TEHYQ-GLFYIQEASSMMPpcALFMDKEPR 112
Cdd:PRK14902 180 SIRVNTLKISVEELIEKLEEEGYEVEESLLSPEALVIE------KGNIagTDLFKdGLITIQDESSMLV--APALDPKGG 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 113 QLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDGRVFGAHLYETLDAIQLDAPCS 192
Cdd:PRK14902 252 DTVLDACAAPGGKTTHIAELLKNTGKVVALDIHEHKLKLIEENAKRLGLTNIETKALDARKVHEKFAEKFDKILVDAPCS 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 193 GEGTVRKDPlSLK-NWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDVCH-FLKErYGDavvFEsLND 270
Cdd:PRK14902 332 GLGVIRRKP-DIKyNKTKEDIESLQEIQLEILESVAQYLKKGGILVYSTCTIEKEENEEVIEaFLEE-HPE---FE-LVP 405
|
250 260 270
....*....|....*....|....*....|....*..
gi 500084139 271 LFKGADKALT---EEGFLHIWPQIYDSEGFFVARIRK 304
Cdd:PRK14902 406 LQHEKPDELVyevKDGYLQILPNDYGTDGFFIAKLRK 442
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
104-303 |
3.00e-50 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 169.53 E-value: 3.00e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 104 ALFMDKEPRQLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDGRVFGAHLYETL- 182
Cdd:pfam01189 1 AILLAPQEGETILDMCAAPGGKTTHIAELMKNQGTVVAVDINKHRLKRVAENIHRLGVTNTIILNGDGRQPDQWLGGVLf 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 183 DAIQLDAPCSGEGTVRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDVC-HFLKERygD 261
Cdd:pfam01189 81 DRILLDAPCSGTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLLKPGGVLVYSTCSVLPEENEAVIeYFLQKH--P 158
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 500084139 262 AVVFESLNdLFKGADKALTEEGFLHIWPQIYDSEGFFVARIR 303
Cdd:pfam01189 159 DVELVPTP-LFEPVGLAIGEQPTLRLLPHTHNGDGFFIAKLR 199
|
|
| PRK14901 |
PRK14901 |
16S rRNA methyltransferase B; Provisional |
27-306 |
2.40e-49 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237856 [Multi-domain] Cd Length: 434 Bit Score: 174.35 E-value: 2.40e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 27 HYCGLPLRLSIRVNTLKITSDALRAILEPRGWQFEPVPWCEDGFWVTVPddcqPGNLTE---HYQGLFYIQEASSMMppC 103
Cdd:PRK14901 171 KWFNQPPSLDLRINPLRTSLEEVQAALAEAGITATPIPGLPQGLRLTGN----PGSIRQlpgYEEGWWTVQDRSAQL--V 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 104 ALFMDKEPRQLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDGR---VFGAHLYE 180
Cdd:PRK14901 245 APLLDPQPGEVILDACAAPGGKTTHIAELMGDQGEIWAVDRSASRLKKLQENAQRLGLKSIKILAADSRnllELKPQWRG 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 181 TLDAIQLDAPCSGEGTVRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDVCH-FLKERY 259
Cdd:PRK14901 325 YFDRILLDAPCSGLGTLHRHPDARWRQTPEKIQELAPLQAELLESLAPLLKPGGTLVYATCTLHPAENEAQIEqFLARHP 404
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 500084139 260 GDAVVFESLNdlfkgadkalteegflhIWPQIYDSEGFFVARIRKTA 306
Cdd:PRK14901 405 DWKLEPPKQK-----------------IWPHRQDGDGFFMAVLRKKS 434
|
|
| PRK14903 |
PRK14903 |
16S rRNA methyltransferase B; Provisional |
32-251 |
6.16e-36 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 184896 [Multi-domain] Cd Length: 431 Bit Score: 137.70 E-value: 6.16e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 32 PLRLSIRVNTLKITSDALRAILEPRGWQFEPVPWCEDGFWVTVPDDcQPGNLTEHYQGLFYIQEASSMMPPcaLFMDKEP 111
Cdd:PRK14903 161 PLPTMLRVNSLAITREEVIKILAEEGTEAVPGKHSPFSLIVRKLGV-NMNDSRVIKDGLATVQGESSQIVP--LLMELEP 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 112 RQLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDGRVFGAHLYETLDAIQLDAPC 191
Cdd:PRK14903 238 GLRVLDTCAAPGGKTTAIAELMKDQGKILAVDISREKIQLVEKHAKRLKLSSIEIKIADAERLTEYVQDTFDRILVDAPC 317
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 192 SGEGTVRKDPLSLKNWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDV 251
Cdd:PRK14903 318 TSLGTARNHPEVLRRVNKEDFKKLSEIQLRIVSQAWKLLEKGGILLYSTCTVTKEENTEV 377
|
|
| rsmB |
TIGR00563 |
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. ... |
35-304 |
9.21e-36 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. The reading frame was originally interpreted as two reading frames, fmu and fmv. The recombinant protein from E. coli was shown to methylate only C967 of small subunit (16S) ribosomal RNA and to produce only m5C at that position. The seed alignment is built from bacterial sequences only. Eukaryotic homologs include Nop2, a protein required for processing pre-rRNA, that is likely also a rRNA methyltransferase, although the fine specificity may differ. Cutoff scores are set to avoid treating archaeal and eukaroytic homologs automatically as functionally equivalent, although they may have very similar roles. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 273141 [Multi-domain] Cd Length: 426 Bit Score: 137.31 E-value: 9.21e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 35 LSIRVNTLKITSDALRAILEPRGWQFEPVPWCEDGFWVTVPDDCQpgNLTEHYQGLFYIQEASSMMppCALFMDKEPRQL 114
Cdd:TIGR00563 166 MWLRINRTKHSRDEWLALLAEAGMKGFPHDLAPDAVRLETPAAVH--ALPGFEEGWVTVQDASAQW--VATWLAPQNEET 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 115 LLDVASAPGSKTTQLAALMhNQGLIIANEYSASRTKALHANLQRMGVaNVAITQFDGRVFGAHLY---ETLDAIQLDAPC 191
Cdd:TIGR00563 242 ILDACAAPGGKTTHILELA-PQAQVVALDIHEHRLKRVYENLKRLGL-TIKAETKDGDGRGPSQWaenEQFDRILLDAPC 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 192 SGEGTVRKDPlSLKnWC--PDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENEDVCHFLKERYGDAVVFESLN 269
Cdd:TIGR00563 320 SATGVIRRHP-DIK-WLrkPRDIAELAELQSEILDAIWPLLKTGGTLVYATCSVLPEENSEQIKAFLQEHPDFPFEKTGT 397
|
250 260 270
....*....|....*....|....*....|....*
gi 500084139 270 DLFKGAdkalteeGFLHIWPQIYDSEGFFVARIRK 304
Cdd:TIGR00563 398 PEQVRD-------GGLQILPHAEEGDGFFYAKLIK 425
|
|
| PRK10901 |
PRK10901 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
37-304 |
6.41e-32 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 236790 [Multi-domain] Cd Length: 427 Bit Score: 126.46 E-value: 6.41e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 37 IRVNTLKITSDALRAILEPRGWQFEPVPWCEDGfwVTVPDDCQPGNLTEHYQGLFYIQEASSMMppCALFMDKEPRQLLL 116
Cdd:PRK10901 174 LRVNRRHHSRDAYLALLAEAGIEAFPHAVGPDA--IRLETPVPVHQLPGFAEGWVSVQDAAAQL--AATLLAPQNGERVL 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 117 DVASAPGSKTTQLAALmHNQGLIIANEYSASRTKALHANLQRMG------VANVAITQ--FDGRVFgahlyetlDAIQLD 188
Cdd:PRK10901 250 DACAAPGGKTAHILEL-APQAQVVALDIDAQRLERVRENLQRLGlkatviVGDARDPAqwWDGQPF--------DRILLD 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 189 APCSGEGTVRKDPlSLKnWC--PDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENED-VCHFLkERYGDAVVf 265
Cdd:PRK10901 321 APCSATGVIRRHP-DIK-WLrrPEDIAALAALQSEILDALWPLLKPGGTLLYATCSILPEENEQqIKAFL-ARHPDAEL- 396
|
250 260 270
....*....|....*....|....*....|....*....
gi 500084139 266 eslndlfkgADKALTEEGFLHIWPQIYDSEGFFVARIRK 304
Cdd:PRK10901 397 ---------LDTGTPQQPGRQLLPGEEDGDGFFYALLIK 426
|
|
| PRK14904 |
PRK14904 |
16S rRNA methyltransferase B; Provisional |
27-307 |
2.19e-31 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237858 [Multi-domain] Cd Length: 445 Bit Score: 125.17 E-value: 2.19e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 27 HYCGLPLRLSIRVNTLKITSDALRAILEprgwqFEPVPWCEDG----FWVTVPDDCQPGnLTehyQGLFYIQEASSMMPP 102
Cdd:PRK14904 173 SYNNQAPLFGFRINRLKTTPEKFLAAPA-----DASVTFEKSGlpnfFLSKDFSLFEPF-LK---LGLVSVQNPTQALAC 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 103 caLFMDKEPRQLLLDVASAPGSKTTQLAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAITQFDGRVFGAHlyETL 182
Cdd:PRK14904 244 --LLLNPQPGSTVLDLCAAPGGKSTFMAELMQNRGQITAVDRYPQKLEKIRSHASALGITIIETIEGDARSFSPE--EQP 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 183 DAIQLDAPCSGEGTV-RKDPLSLKnWCPDEIEAIAELQRDLIDSAFQALKPGGVLVYSTCTLNRRENE-DVCHFLKeRYG 260
Cdd:PRK14904 320 DAILLDAPCTGTGVLgRRAELRWK-LTPEKLAELVGLQAELLDHAASLLKPGGVLVYATCSIEPEENElQIEAFLQ-RHP 397
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 500084139 261 DAVVFESLNDLFKGADKALTEEGFLHIWPQiyDSEGF---FVARIRKTAS 307
Cdd:PRK14904 398 EFSAEPSPGSLPEPFHEVAHPKGAILTLPG--EHEGFdggFAQRLRKNAG 445
|
|
| Methyltr_RsmF_N |
pfam17125 |
N-terminal domain of 16S rRNA methyltransferase RsmF; This is the N-terminal domain of the ... |
4-98 |
4.79e-28 |
|
N-terminal domain of 16S rRNA methyltransferase RsmF; This is the N-terminal domain of the RsmF methyl transferase. RsmF is a multi-site-specific methyltransferase that is responsible for the synthesis of three modifications on cytidines in 16S ribosomal RNA. The N-terminus is critical for stabilising the catalytic core of the enzyme.
Pssm-ID: 465356 [Multi-domain] Cd Length: 88 Bit Score: 106.41 E-value: 4.79e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 4 LNQKFINSIAQEMPPhlSMDDFVHYCGLPLRLSIRVNTLKITSDALRAILEprgWQFEPVPWCEDGFWvtVPDDCQPGNL 83
Cdd:pfam17125 1 LPEAFIERMRALLGD--EYEAFLAAYDEPRPVGLRVNTLKISVEEFLKLSP---FELEPVPWCEEGFY--LEERPRPGKH 73
|
90
....*....|....*
gi 500084139 84 TEHYQGLFYIQEASS 98
Cdd:pfam17125 74 PYHHAGLYYIQEPSA 88
|
|
| Methyltranf_PUA |
pfam13636 |
RNA-binding PUA-like domain of methyltransferase RsmF; Methyltranf_PUA is the second of two ... |
412-460 |
3.84e-10 |
|
RNA-binding PUA-like domain of methyltransferase RsmF; Methyltranf_PUA is the second of two C-terminal domains found on bacterial methyltransferase RsmF that modifies the 16S ribosomal RNA. It has some structural similarity to the RNA-binding PUA domains suggesting that it is involved in RNA recognition. It lies downstream of the catalytic centre of this methyltransferase, family pfam01189.
Pssm-ID: 433368 [Multi-domain] Cd Length: 50 Bit Score: 55.23 E-value: 3.84e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 500084139 412 AKQYLMGRDIALDNAgKAQGEKILSLHGAPLGIAKHLGNKLKNSLPRDL 460
Cdd:pfam13636 1 ALRYLRGETIELDGD-LKAGWVLVTYDGFPLGWGKLLGGRLKNLYPKGL 48
|
|
| CobL |
COG2242 |
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part ... |
111-249 |
1.91e-03 |
|
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 441843 [Multi-domain] Cd Length: 403 Bit Score: 40.54 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500084139 111 PRQLLLDVASAPGSKTTQlAALMHNQGLIIANEYSASRTKALHANLQRMGVANVAItqfdgrvfgahlyetldaIQLDAP 190
Cdd:COG2242 247 PGDVLWDIGAGSGSVSIE-AARLAPGGRVYAIERDPERAALIRANARRFGVPNVEV------------------VEGEAP 307
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 500084139 191 csgegtvrkdplslknwcpdeiEAIAELQR--------------DLIDSAFQALKPGGVLVYSTCTLnrrENE 249
Cdd:COG2242 308 ----------------------EALADLPDpdavfiggsggnlpEILEACWARLRPGGRLVANAVTL---ETL 355
|
|
| |
