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Conserved domains on  [gi|500096188|ref|WP_011772195|]
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MIP/aquaporin family protein [Borrelia turicatae]

Protein Classification

MIP/aquaporin family protein( domain architecture ID 10001739)

MIP (Major Intrinsic Protein)/aquaporin family protein similar to aquaporin that permits osmotically driven movement of water in both directions, and glycerol uptake facilitator protein that mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism

CATH:  1.20.1080.10
Gene Ontology:  GO:0055085|GO:0015267
PubMed:  11964478|8849412|11473620
SCOP:  3000508
TCDB:  1.A.8

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 6-209 3.02e-58

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


:

Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 184.56  E-value: 3.02e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   6 FKEFIAEFLGTFILLALGTGSVAMTTLFPSNpsvtgeiikGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATI 85
Cdd:COG0580    3 MKRLLAEFLGTFILVLLGCGVVAVLAGTKGG---------IGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  86 GRFPTAKLFHYISAQILGAFSGALMTLIVFYPKWIEIDPAFeNTQGIMSTFPAVP-GFWPGFIDQIFGTFLLMFLVLVVG 164
Cdd:COG0580   74 GRFPWKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATEDGG-AKLGVFATSPAIGySLGAAFLTEIIGTFVLVFVILGIT 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 500096188 165 KfiKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRI 209
Cdd:COG0580  153 D--KRAAPGGLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRL 195
 
Name Accession Description Interval E-value
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 6-209 3.02e-58

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 184.56  E-value: 3.02e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   6 FKEFIAEFLGTFILLALGTGSVAMTTLFPSNpsvtgeiikGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATI 85
Cdd:COG0580    3 MKRLLAEFLGTFILVLLGCGVVAVLAGTKGG---------IGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  86 GRFPTAKLFHYISAQILGAFSGALMTLIVFYPKWIEIDPAFeNTQGIMSTFPAVP-GFWPGFIDQIFGTFLLMFLVLVVG 164
Cdd:COG0580   74 GRFPWKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATEDGG-AKLGVFATSPAIGySLGAAFLTEIIGTFVLVFVILGIT 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 500096188 165 KfiKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRI 209
Cdd:COG0580  153 D--KRAAPGGLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRL 195
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
 5-214 3.95e-48

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 160.68  E-value: 3.95e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   5 RFKEFIAEFLGTFILLALGTGSVAMTTLFPSNpsvtgeiikGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLAT 84
Cdd:PTZ00016  49 NVREYVAEFLGTFVLLFFGEGVVATTHTVGNN---------GDYLAITIGWGLGVTFGLLVSAGISGGHLNPAVTLGNAV 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  85 IGRFPTAKLFHYISAQILGAFSGALMTLIVFY--------PKWIEIDPAFENTqGIMSTFPAVPGFWPgFIDQIFGTFLL 156
Cdd:PTZ00016 120 FGKFPWKKLPGYFVAQLLGAFVGAACVYGLYYgffkdhgiPELPWETMANGFA-GVFATYPREGNFYA-IFSELILTAIL 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 500096188 157 MFLVLVVgkfikGDTQNP----FFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRILLLLA 214
Cdd:PTZ00016 198 LLVILAI-----TDPNNCpafnYLPVAVGLLVFVIGISFGGNTGYALNPARDLGPRLFSAIL 254
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 7-211 7.24e-45

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 150.48  E-value: 7.24e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   7 KEFIAEFLGTFILLALGTGSVAMTTLFPSNPsvtgeiikGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATIG 86
Cdd:cd00333    1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGGAS--------GGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGG 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  87 RFPTAKLFHYISAQILGAFSGALMTLIVFYPKWIEIDPAFENTQGIMSTFPAvPG--FWPGFIDQIFGTFLLMFLVLVVG 164
Cdd:cd00333   73 RFPLIRVIPYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGIFGTYPS-PGvsNGNAFFVEFIGTFILVLVVFATT 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 500096188 165 KFIKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRILL 211
Cdd:cd00333  152 DDPNGPPPGGLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFT 198
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 11-219 4.10e-42

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 142.82  E-value: 4.10e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   11 AEFLGTFILLALGTGSVAMTTLfpsnPSVTGEIIKGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATIGRFPT 90
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALGVNV----AGAYGAVGGGQFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   91 AKLFHYISAQILGAFSGALMTLIVFYPKwieidpaFENTQGIMSTFPAVPGFWPGFIDQIFGTFLLMFLVLVVGKFIKGD 170
Cdd:TIGR00861  77 KRVPVYIVAQLIGAILGAALLYGLTSGL-------FPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTDDRNRV 149

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 500096188  171 TQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRILLLLAGFKNH 219
Cdd:TIGR00861 150 PRGGFAPLAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGLAGWGNH 198
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 7-211 5.49e-32

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 117.03  E-value: 5.49e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188    7 KEFIAEFLGTFILLALGTGSVAMTTLFPSNPSVTGEIIkggytnIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATIG 86
Cdd:pfam00230   9 RAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLA------VALAFGLALATLVYCAGHISGAHLNPAVTLALLVGR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   87 RFPTAKLFHYISAQILGAFSGALMTLIVFYpkwieidPAFENTQGIMSTFPAVpGFWPGFIDQIFGTFLLMFLVLVVGKF 166
Cdd:pfam00230  83 RFSLLRAIFYIVAQLLGAIAGAALLYGVTV-------GLQRAGLFANTLAPGV-NAGQAFVVEIILTFQLVYCVFATTDD 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 500096188  167 IKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRILL 211
Cdd:pfam00230 155 RRNGSLGTVAPLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVL 199
 
Name Accession Description Interval E-value
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 6-209 3.02e-58

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 184.56  E-value: 3.02e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   6 FKEFIAEFLGTFILLALGTGSVAMTTLFPSNpsvtgeiikGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATI 85
Cdd:COG0580    3 MKRLLAEFLGTFILVLLGCGVVAVLAGTKGG---------IGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  86 GRFPTAKLFHYISAQILGAFSGALMTLIVFYPKWIEIDPAFeNTQGIMSTFPAVP-GFWPGFIDQIFGTFLLMFLVLVVG 164
Cdd:COG0580   74 GRFPWKDVLPYIIAQLLGAFLGAALVYLIYGGHFDATEDGG-AKLGVFATSPAIGySLGAAFLTEIIGTFVLVFVILGIT 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 500096188 165 KfiKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRI 209
Cdd:COG0580  153 D--KRAAPGGLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRL 195
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
 5-214 3.95e-48

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 160.68  E-value: 3.95e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   5 RFKEFIAEFLGTFILLALGTGSVAMTTLFPSNpsvtgeiikGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLAT 84
Cdd:PTZ00016  49 NVREYVAEFLGTFVLLFFGEGVVATTHTVGNN---------GDYLAITIGWGLGVTFGLLVSAGISGGHLNPAVTLGNAV 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  85 IGRFPTAKLFHYISAQILGAFSGALMTLIVFY--------PKWIEIDPAFENTqGIMSTFPAVPGFWPgFIDQIFGTFLL 156
Cdd:PTZ00016 120 FGKFPWKKLPGYFVAQLLGAFVGAACVYGLYYgffkdhgiPELPWETMANGFA-GVFATYPREGNFYA-IFSELILTAIL 197

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 500096188 157 MFLVLVVgkfikGDTQNP----FFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRILLLLA 214
Cdd:PTZ00016 198 LLVILAI-----TDPNNCpafnYLPVAVGLLVFVIGISFGGNTGYALNPARDLGPRLFSAIL 254
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 7-211 7.24e-45

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 150.48  E-value: 7.24e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   7 KEFIAEFLGTFILLALGTGSVAMTTLFPSNPsvtgeiikGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATIG 86
Cdd:cd00333    1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGGAS--------GGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGG 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  87 RFPTAKLFHYISAQILGAFSGALMTLIVFYPKWIEIDPAFENTQGIMSTFPAvPG--FWPGFIDQIFGTFLLMFLVLVVG 164
Cdd:cd00333   73 RFPLIRVIPYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGIFGTYPS-PGvsNGNAFFVEFIGTFILVLVVFATT 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 500096188 165 KFIKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRILL 211
Cdd:cd00333  152 DDPNGPPPGGLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFT 198
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 11-219 4.10e-42

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 142.82  E-value: 4.10e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   11 AEFLGTFILLALGTGSVAMTTLfpsnPSVTGEIIKGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATIGRFPT 90
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALGVNV----AGAYGAVGGGQFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   91 AKLFHYISAQILGAFSGALMTLIVFYPKwieidpaFENTQGIMSTFPAVPGFWPGFIDQIFGTFLLMFLVLVVGKFIKGD 170
Cdd:TIGR00861  77 KRVPVYIVAQLIGAILGAALLYGLTSGL-------FPGNLAVNGSASAGVSSGQAFFVEFIGTAILVLVIFATTDDRNRV 149

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 500096188  171 TQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRILLLLAGFKNH 219
Cdd:TIGR00861 150 PRGGFAPLAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGLAGWGNH 198
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 7-211 5.49e-32

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 117.03  E-value: 5.49e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188    7 KEFIAEFLGTFILLALGTGSVAMTTLFPSNPSVTGEIIkggytnIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATIG 86
Cdd:pfam00230   9 RAVIAEFLATLLFVFFGVGSALGVKKLVSSLAVSGLLA------VALAFGLALATLVYCAGHISGAHLNPAVTLALLVGR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   87 RFPTAKLFHYISAQILGAFSGALMTLIVFYpkwieidPAFENTQGIMSTFPAVpGFWPGFIDQIFGTFLLMFLVLVVGKF 166
Cdd:pfam00230  83 RFSLLRAIFYIVAQLLGAIAGAALLYGVTV-------GLQRAGLFANTLAPGV-NAGQAFVVEIILTFQLVYCVFATTDD 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 500096188  167 IKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRILL 211
Cdd:pfam00230 155 RRNGSLGTVAPLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVL 199
PLN00183 PLN00183
putative aquaporin NIP7; Provisional
 10-210 1.62e-20

putative aquaporin NIP7; Provisional


Pssm-ID: 215092  Cd Length: 274  Bit Score: 87.60  E-value: 1.62e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  10 IAEFLGTFILLALGTGSVAMTTLFPSNPSVTGEIIKGGYTNIVLgwglgvtfgVYTAARISGAHLNPAISIGLATIGRFP 89
Cdd:PLN00183  49 LAEMVGTFILMFCVCGIIASTQLSGGEVGLLEYAATAGLTVVVV---------VFSIGSISGAHVNPSVTIAFATFGHFP 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  90 TAKLFHYISAQILGAFSGALMTLIVFYPKwieidpafentQGIMSTFPA---VPGFWPGFIdqifGTFLLMFLVLVVGKf 166
Cdd:PLN00183 120 WSKVPLYITAQTVGSVLATYVGVSVYGVK-----------ADLMTTKPAqgcSSAFWVEFI----ATFIVMFLAASLTS- 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 500096188 167 iKGDTQNPFFPFIIG-SIVLAIGISfGGMNGYAINPARDLGPRIL 210
Cdd:PLN00183 184 -QPQSLGHLSGFVIGiAIGLAVLIT-GPVSGGSMNPARSLGPAIV 226
PLN00184 PLN00184
aquaporin NIP1; Provisional
 6-210 3.52e-17

aquaporin NIP1; Provisional


Pssm-ID: 177778  Cd Length: 296  Bit Score: 78.91  E-value: 3.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   6 FKEFIAEFLGTFILLALGTGSVAMTTLFPSNPSVTGeiikggytnIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATI 85
Cdd:PLN00184  54 LQKLIAEVLGTYFLVFTGCASVVVNMQNDNVVTLPG---------IAIVWGLTIMVLIYSLGHISGAHINPAVTIAFASC 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  86 GRFPTAKLFHYISAQILGAFSGALMTLIVFypkWIEIDPAFENTQGIMSTFPAVPGFwPGFIDQIFGTFLLMFlvLVVGK 165
Cdd:PLN00184 125 GRFPLKQVPAYVISQVIGSTLAAATLRLLF---GLDHDVCSGKHDVFIGSSPVGSDL-QAFVMEFIVTFYLMF--IISGV 198

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 500096188 166 FIKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRIL 210
Cdd:PLN00184 199 ATDNRAIGELAGLAIGSTVLLNVLIAAPVSSASMNPGRSLGPAMV 243
PRK05420 PRK05420
aquaporin Z; Provisional
 6-108 6.75e-16

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 74.23  E-value: 6.75e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   6 FKEFIAEFLGTFILLALGTGSVAMTTLFPSnpsvtgeiIKGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATI 85
Cdd:PRK05420   2 FKKLAAEFFGTFWLVFGGCGSAVLAAAFPE--------LGIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAG 73

                         90       100
                 ....*....|....*....|...
gi 500096188  86 GRFPTAKLFHYISAQILGAFSGA 108
Cdd:PRK05420  74 GRFPAKELVPYIIAQVVGGIAAA 96
PLN00182 PLN00182
putative aquaporin NIP4; Provisional
 7-211 2.66e-14

putative aquaporin NIP4; Provisional


Pssm-ID: 165748  Cd Length: 283  Bit Score: 70.71  E-value: 2.66e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   7 KEFIAEFLGTFILLALGTGSVAMTTLFPSNPSVTGeiikggytnIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATIG 86
Cdd:PLN00182  43 QKLIAEMIGTYFIIFSGCGVVVVNVLYGGTITFPG---------ICVTWGLIVMVMIYSTGHISGAHFNPAVTVTFAIFR 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  87 RFPTAKLFHYISAQILGAFSGALMTLIVFypkwiEIDP-AFentqgimstFPAVPGFWPG--FIDQIFGTFLLMFlvLVV 163
Cdd:PLN00182 114 RFPWYQVPLYIGAQLTGSLLASLTLRLMF-----NVTPeAF---------FGTTPTDSSGqaLVAEIIISFLLMF--VIS 177

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 500096188 164 GKFIKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRILL 211
Cdd:PLN00182 178 GVATDSRAVGELAGIAVGMTIILNVFVAGPISGASMNPARSLGPAIVM 225
PLN00026 PLN00026
aquaporin NIP; Provisional
 11-209 4.50e-13

aquaporin NIP; Provisional


Pssm-ID: 177663 [Multi-domain]  Cd Length: 298  Bit Score: 67.58  E-value: 4.50e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  11 AEFLGTFILLALGTGSVAMTTLFPSNPSVTGEIIKGGytnivlgwgLGVTFGVYTAARISGAHLNPAISIGLATIGRFPT 90
Cdd:PLN00026  76 AEFVGTFILIFAATAGPIVNQKYDGAETLIGNAACAG---------LAVMIVILSTGHISGAHLNPSLTIAFAALRHFPW 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  91 AKLFHYISAQILGAFSGALMTLIVFYPkwieidpafentqgIMSTFPAVP--GFWPGFIDQIFGTFLLMFLVLVVGKfik 168
Cdd:PLN00026 147 KHVPAYIAAQVSASICASFALKGVFHP--------------FMSGGVTVPsvSTGQAFALEFIITFNLLFVVTAVAT--- 209

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 500096188 169 gDTQ--NPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRI 209
Cdd:PLN00026 210 -DTRavGELAGIAVGATVMLNILVAGPSTGGSMNPVRTLGPAV 251
PLN00166 PLN00166
aquaporin TIP2; Provisional
 6-210 5.08e-13

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 66.50  E-value: 5.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   6 FKEFIAEFLGTFILLALGTGSVAMTTLFPSNpsvtGEIIKGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATI 85
Cdd:PLN00166  18 LKAYLSEFIATLLFVFAGVGSAIAFAKLTSD----AALDPAGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTLGLAIG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  86 GRFPTAKLFHYISAQILGAFSGALMTLIVFYPKWIEidpafenTQGIMSTFPAVpgfwPGFIDQIFGTFLLMFLVLVVGK 165
Cdd:PLN00166  94 GNITIITGFFYWIAQCLGSIVACLLLVFVTNGESVP-------THGVAAGLGAI----EGVVMEIVVTFALVYTVYATAA 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 500096188 166 FIKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGPRIL 210
Cdd:PLN00166 163 DPKKGSLGTIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVV 207
PLN00027 PLN00027
aquaporin TIP; Provisional
 6-207 1.65e-07

aquaporin TIP; Provisional


Pssm-ID: 177664  Cd Length: 252  Bit Score: 50.94  E-value: 1.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   6 FKEFIAEFLGTFILLALGTGSVAMTTLFPSNPSVTgeiiKGGYTNIVLGWGLGVTFGVYTAARISGAHLNPAISIGLATI 85
Cdd:PLN00027  20 LKAALAEFISTLIFVFAGEGSGMAFNKLTDNGSTT----PAGLVAAALAHAFALFVAVSVGANISGGHVNPAVTFGAFIG 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188  86 GRFPTAKLFHYISAQILGAFSGALmtLIVFYPKWIEIdPAFENTQGImstfpavpGFWPGFIDQIFGTFLLMFLVLVVGK 165
Cdd:PLN00027  96 GNITLLRGILYWIAQLLGSVVACL--LLKFSTGGLET-SAFSLSSGV--------GVWNAFVFEIVMTFGLVYTVYATAV 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 500096188 166 FIKGDTQNPFFPFIIGSIVLAIGISFGGMNGYAINPARDLGP 207
Cdd:PLN00027 165 DPKKGDLGIIAPIAIGFIVGANILAGGAFDGASMNPAVSFGP 206
PLN00167 PLN00167
aquaporin TIP5; Provisional
 6-110 9.32e-06

aquaporin TIP5; Provisional


Pssm-ID: 215085  Cd Length: 256  Bit Score: 45.66  E-value: 9.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500096188   6 FKEFIAEFLGTFILLALGTGSV-AMTTLFPSNPSVTGEIIKGGYTNivlgwGLGVTFGVYTAARISGAHLNPAISIGLAT 84
Cdd:PLN00167  22 LRSYLAEFISTFFFVFAAVGSAmSSRKLMPDAASDPSSLLIVAIAN-----AFALSSAVYIAANISGGHVNPAVTFGMAV 96

                         90       100
                 ....*....|....*....|....*...
gi 500096188  85 IGRF--PTAkLFHYISaQILGAFSGALM 110
Cdd:PLN00167  97 GGHIsvPTA-MFYWIS-QMLASVMACLF 122
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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