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Conserved domains on  [gi|500232254|ref|WP_011901847|]
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MULTISPECIES: type-F conjugative transfer system pilin acetylase TraX [Enterobacterales]

Protein Classification

TraX family protein( domain architecture ID 5732)

TraX family protein similar to Dichelobacter nodosus fimbrial assembly protein FimC, serogroup H1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TraX super family cl05434
TraX protein; This family consists of several bacterial TraX proteins. TraX is responsible for ...
16-245 1.67e-67

TraX protein; This family consists of several bacterial TraX proteins. TraX is responsible for the amino-terminal acetylation of F-pilin subunits.


The actual alignment was detected with superfamily member PRK13706:

Pssm-ID: 414418  Cd Length: 248  Bit Score: 208.67  E-value: 1.67e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  16 DCWLQRLLVWTPGQTDLIKTVALLLMVADHISMLCGLDNDWLRLAGRGAFPLFGLVWAMNLARHPQIQQRALNRLWIWAG 95
Cdd:PRK13706  19 DTWLQSLLVWSPGQRDIIKTVALVLMVLDHINRILHLDQEWMFLAGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGI 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  96 VAQGGWILAGLRPDLGNILFAFAVSGQALALMQ-RHGPRTwPLSLMLVLAWLPFSAGSYGLAGVVMLMLACGVCMTGRRT 174
Cdd:PRK13706  99 IAQFAYYLAGFPWYEGNILFAFAVAAQVLTWCEtRSGWRT-AAAILLMALWGPLSGTSYGIAGLLMLAVSHRLYRAEDRA 177
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 500232254 175 TRTGLALCLALAILALNAADSPAFAIAGLVIPGVTLTVLSRTCCRVPRFWPREFFPLFYAVHLAVIGLMVM 245
Cdd:PRK13706 178 ERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSCAGKSLPRFWPGDFFPVFYACHLAVLGVLAL 248
 
Name Accession Description Interval E-value
PRK13706 PRK13706
conjugal transfer pilus acetylase TraX;
16-245 1.67e-67

conjugal transfer pilus acetylase TraX;


Pssm-ID: 184262  Cd Length: 248  Bit Score: 208.67  E-value: 1.67e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  16 DCWLQRLLVWTPGQTDLIKTVALLLMVADHISMLCGLDNDWLRLAGRGAFPLFGLVWAMNLARHPQIQQRALNRLWIWAG 95
Cdd:PRK13706  19 DTWLQSLLVWSPGQRDIIKTVALVLMVLDHINRILHLDQEWMFLAGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGI 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  96 VAQGGWILAGLRPDLGNILFAFAVSGQALALMQ-RHGPRTwPLSLMLVLAWLPFSAGSYGLAGVVMLMLACGVCMTGRRT 174
Cdd:PRK13706  99 IAQFAYYLAGFPWYEGNILFAFAVAAQVLTWCEtRSGWRT-AAAILLMALWGPLSGTSYGIAGLLMLAVSHRLYRAEDRA 177
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 500232254 175 TRTGLALCLALAILALNAADSPAFAIAGLVIPGVTLTVLSRTCCRVPRFWPREFFPLFYAVHLAVIGLMVM 245
Cdd:PRK13706 178 ERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSCAGKSLPRFWPGDFFPVFYACHLAVLGVLAL 248
TraX_Ftype TIGR02755
type-F conjugative transfer system pilin acetylase TraX; TraX is responsible for the ...
22-245 1.02e-56

type-F conjugative transfer system pilin acetylase TraX; TraX is responsible for the acetylation of the F-pilin TraA during conjugative plasmid transfer. The purpose of this acetylation is unclear, but the reported transcriptional regulation of TraX may indicate that it is involved in the process of pilu extension/retraction.


Pssm-ID: 131802  Cd Length: 224  Bit Score: 180.47  E-value: 1.02e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254   22 LLVWTPGQTDLIKTVALLLMVADHISMLCGLDNDWLRLAGRGAFPLFGLVWAMNLARHPQIQQRALNRLWIWAGVAQGGW 101
Cdd:TIGR02755   1 VLNWSPGQRDVIKTVALVLMVGDHINTIFQLDQEWLFLAGRGAFPLFALVWGLNLSRHTHIRQHAINRLWGWALIAQPGY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  102 ILAGLRPDLGNILFAFAVSGQALALMQRHGPRTWPLSLMLVLAWLPFSAGSYGLAGVVMLMLACGVCMTGRRTTRTGLAL 181
Cdd:TIGR02755  81 WLAGFPWYEGNILFAFAVVAQVLLWCESRTARNGAAAFLLLMGWTPLSGTSYGIAGLLMLAGALRLYRVRDTEERLALFA 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 500232254  182 CLALAILALNAADSPAFAIAGLVIPGVTLTVLSRTCCRVPRFWPREFFPLFYAVHLAVIGLMVM 245
Cdd:TIGR02755 161 CLLLLVPALNLRTSDAAAVAGLILTLLTVGLVSATGKSRPRFWPGDFFPPFYACHLAFLGFLVR 224
TraX pfam05857
TraX protein; This family consists of several bacterial TraX proteins. TraX is responsible for ...
29-244 7.15e-38

TraX protein; This family consists of several bacterial TraX proteins. TraX is responsible for the amino-terminal acetylation of F-pilin subunits.


Pssm-ID: 399098  Cd Length: 215  Bit Score: 131.71  E-value: 7.15e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254   29 QTDLIKTVALLLMVADHISMLCGLDNDWLRLAGRGAFPLFGLVWAMNLARHPQIQQRALNRLWIWAGVAQGGWILAGLRP 108
Cdd:pfam05857   1 SLDLLKWLALLLMVIDHVNLLFLNNNPVLFELGRVAFPLFCLVLAENLARHTRNRWRYLGRLLLFGLISEVPFDLAGADW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  109 DLGNILFAFAVSGQALALMQ-RHGPRTWPLSLMLVLAWLPFSAGSYGLAGVVMLMLACGVC-MTGRRTTRTGLALCLALA 186
Cdd:pfam05857  81 NPLNILFTLALGLIVLWLVEhRKKNTTVLAIVALTVLIVPLSSLDYGWAGVLLGLVFWLFYrRPALRYLASPAVAALAVL 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 500232254  187 ILALNAADSPAFAIAGLVIPGVTltvLSRTCCRVPRFWPREFFPLFYAVHLAVIGLMV 244
Cdd:pfam05857 161 ALNLLGFISNRALWALLALPLLG---LARAKNGVRIPRLRRFFYAFYPGHLAVLGLLR 215
 
Name Accession Description Interval E-value
PRK13706 PRK13706
conjugal transfer pilus acetylase TraX;
16-245 1.67e-67

conjugal transfer pilus acetylase TraX;


Pssm-ID: 184262  Cd Length: 248  Bit Score: 208.67  E-value: 1.67e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  16 DCWLQRLLVWTPGQTDLIKTVALLLMVADHISMLCGLDNDWLRLAGRGAFPLFGLVWAMNLARHPQIQQRALNRLWIWAG 95
Cdd:PRK13706  19 DTWLQSLLVWSPGQRDIIKTVALVLMVLDHINRILHLDQEWMFLAGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGI 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  96 VAQGGWILAGLRPDLGNILFAFAVSGQALALMQ-RHGPRTwPLSLMLVLAWLPFSAGSYGLAGVVMLMLACGVCMTGRRT 174
Cdd:PRK13706  99 IAQFAYYLAGFPWYEGNILFAFAVAAQVLTWCEtRSGWRT-AAAILLMALWGPLSGTSYGIAGLLMLAVSHRLYRAEDRA 177
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 500232254 175 TRTGLALCLALAILALNAADSPAFAIAGLVIPGVTLTVLSRTCCRVPRFWPREFFPLFYAVHLAVIGLMVM 245
Cdd:PRK13706 178 ERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSCAGKSLPRFWPGDFFPVFYACHLAVLGVLAL 248
TraX_Ftype TIGR02755
type-F conjugative transfer system pilin acetylase TraX; TraX is responsible for the ...
22-245 1.02e-56

type-F conjugative transfer system pilin acetylase TraX; TraX is responsible for the acetylation of the F-pilin TraA during conjugative plasmid transfer. The purpose of this acetylation is unclear, but the reported transcriptional regulation of TraX may indicate that it is involved in the process of pilu extension/retraction.


Pssm-ID: 131802  Cd Length: 224  Bit Score: 180.47  E-value: 1.02e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254   22 LLVWTPGQTDLIKTVALLLMVADHISMLCGLDNDWLRLAGRGAFPLFGLVWAMNLARHPQIQQRALNRLWIWAGVAQGGW 101
Cdd:TIGR02755   1 VLNWSPGQRDVIKTVALVLMVGDHINTIFQLDQEWLFLAGRGAFPLFALVWGLNLSRHTHIRQHAINRLWGWALIAQPGY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  102 ILAGLRPDLGNILFAFAVSGQALALMQRHGPRTWPLSLMLVLAWLPFSAGSYGLAGVVMLMLACGVCMTGRRTTRTGLAL 181
Cdd:TIGR02755  81 WLAGFPWYEGNILFAFAVVAQVLLWCESRTARNGAAAFLLLMGWTPLSGTSYGIAGLLMLAGALRLYRVRDTEERLALFA 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 500232254  182 CLALAILALNAADSPAFAIAGLVIPGVTLTVLSRTCCRVPRFWPREFFPLFYAVHLAVIGLMVM 245
Cdd:TIGR02755 161 CLLLLVPALNLRTSDAAAVAGLILTLLTVGLVSATGKSRPRFWPGDFFPPFYACHLAFLGFLVR 224
TraX pfam05857
TraX protein; This family consists of several bacterial TraX proteins. TraX is responsible for ...
29-244 7.15e-38

TraX protein; This family consists of several bacterial TraX proteins. TraX is responsible for the amino-terminal acetylation of F-pilin subunits.


Pssm-ID: 399098  Cd Length: 215  Bit Score: 131.71  E-value: 7.15e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254   29 QTDLIKTVALLLMVADHISMLCGLDNDWLRLAGRGAFPLFGLVWAMNLARHPQIQQRALNRLWIWAGVAQGGWILAGLRP 108
Cdd:pfam05857   1 SLDLLKWLALLLMVIDHVNLLFLNNNPVLFELGRVAFPLFCLVLAENLARHTRNRWRYLGRLLLFGLISEVPFDLAGADW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  109 DLGNILFAFAVSGQALALMQ-RHGPRTWPLSLMLVLAWLPFSAGSYGLAGVVMLMLACGVC-MTGRRTTRTGLALCLALA 186
Cdd:pfam05857  81 NPLNILFTLALGLIVLWLVEhRKKNTTVLAIVALTVLIVPLSSLDYGWAGVLLGLVFWLFYrRPALRYLASPAVAALAVL 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 500232254  187 ILALNAADSPAFAIAGLVIPGVTltvLSRTCCRVPRFWPREFFPLFYAVHLAVIGLMV 244
Cdd:pfam05857 161 ALNLLGFISNRALWALLALPLLG---LARAKNGVRIPRLRRFFYAFYPGHLAVLGLLR 215
PRK13882 PRK13882
conjugal transfer protein TrbP; Provisional
23-143 1.26e-08

conjugal transfer protein TrbP; Provisional


Pssm-ID: 237542  Cd Length: 232  Bit Score: 53.92  E-value: 1.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500232254  23 LVWTPGQTDLIKTVALLLMVADHIS-MLCGLDNDWLRLAGRGAFPLFGLVWAMNLARHPQIQQ----RALNRLWIWAGVA 97
Cdd:PRK13882   4 LRMSSGTREALKWLALLLMTGDHVNkYLFNGTLPVLFEAGRVALPLFVFVLAYNLARPGALERgdygRTMKRLALFGLLA 83
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 500232254  98 QG-----GWILAGLRPdlGNILFAFAVSGQALALMQRHGPRTWPLSLMLVL 143
Cdd:PRK13882  84 SVpfvalGGLFGGWWP--LNVLFTLLVATATAYLVERGGKLHLVAAGVVFL 132
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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