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Conserved domains on  [gi|500264322|ref|WP_011915206|]
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sodium:proton antiporter [Stutzerimonas stutzeri]

Protein Classification

sodium:proton antiporter( domain architecture ID 10002944)

sodium:proton antiporter is a transmembrane protein that plays a critical role in maintaining intracellular pH levels in bacteria and may contribute to salt tolerance in plants

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
1-115 1.78e-38

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


:

Pssm-ID: 440630  Cd Length: 113  Bit Score: 125.61  E-value: 1.78e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIraGESSLPADAANPLPQALVLTA 80
Cdd:COG1006    1 MELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGGLTGGAPPIL--GEGPPAAPYADPLPQALVLTA 78

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 500264322  81 IVIGFSLTAFFAALALQTYRRLGSVDLRQIDAAER 115
Cdd:COG1006   79 IVIGFAVTAFLLALAYRIYQLYGTDDVDELREDER 113
 
Name Accession Description Interval E-value
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
1-115 1.78e-38

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 125.61  E-value: 1.78e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIraGESSLPADAANPLPQALVLTA 80
Cdd:COG1006    1 MELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGGLTGGAPPIL--GEGPPAAPYADPLPQALVLTA 78

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 500264322  81 IVIGFSLTAFFAALALQTYRRLGSVDLRQIDAAER 115
Cdd:COG1006   79 IVIGFAVTAFLLALAYRIYQLYGTDDVDELREDER 113
PRK12658 PRK12658
Na+/H+ antiporter subunit C;
1-120 5.87e-37

Na+/H+ antiporter subunit C;


Pssm-ID: 183658  Cd Length: 125  Bit Score: 122.09  E-value: 5.87e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIRAGESSLPADAANPLPQALVLTA 80
Cdd:PRK12658   1 MEALFAILVGVFFAAAIYLMLSRHIIRILFGLALLGNAVNLLIFTAGRLTREVPPLIPAGADVLAEGAANPLPQALILTA 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 500264322  81 IVIGFSLTAFFAALALQTYRRLGSVDLRQIDAAERLGSPT 120
Cdd:PRK12658  81 IVIGFGLLAFLLVLAYRAYQDLGTDDTDEMRVAEPVEEPL 120
2a6301s03 TIGR00941
Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and ...
 1-107 1.45e-19

Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273354  Cd Length: 104  Bit Score: 77.15  E-value: 1.45e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322    1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIRAGESSLpadaANPLPQALVLTA 80
Cdd:TIGR00941   1 MESIFALIIGILTASGVYLLLSRSVVRVVLGLALLGYAVNLFILTMGGLENKAPPILTLPVGPY----VDPLPQALILTA 76

                          90       100
                  ....*....|....*....|....*..
gi 500264322   81 IVIGFSLTAFFAALALQTYRRLGSVDL 107
Cdd:TIGR00941  77 IVIGFATTALFLVVALRAYQVAGTDDV 103
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-115 8.38e-12

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 57.19  E-value: 8.38e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322    4 LFALSIAVLAGCSLYLIL-SRHIVRVLLGVTMLSAAINLVIFFAGRIvtntpaviragesslpadAANPLPQALVLTAIV 82
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLlRRNLLRVLLSLELMLNAVNLALVLFGRL------------------TADPLPQALILTAIV 62

                          90       100       110
                  ....*....|....*....|....*....|...
gi 500264322   83 IGFSLTAFFAALALQTYRRLGSVDLRQIDAAER 115
Cdd:pfam00420  63 IAAAEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
1-115 1.78e-38

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 125.61  E-value: 1.78e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIraGESSLPADAANPLPQALVLTA 80
Cdd:COG1006    1 MELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGGLTGGAPPIL--GEGPPAAPYADPLPQALVLTA 78

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 500264322  81 IVIGFSLTAFFAALALQTYRRLGSVDLRQIDAAER 115
Cdd:COG1006   79 IVIGFAVTAFLLALAYRIYQLYGTDDVDELREDER 113
PRK12658 PRK12658
Na+/H+ antiporter subunit C;
1-120 5.87e-37

Na+/H+ antiporter subunit C;


Pssm-ID: 183658  Cd Length: 125  Bit Score: 122.09  E-value: 5.87e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIRAGESSLPADAANPLPQALVLTA 80
Cdd:PRK12658   1 MEALFAILVGVFFAAAIYLMLSRHIIRILFGLALLGNAVNLLIFTAGRLTREVPPLIPAGADVLAEGAANPLPQALILTA 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 500264322  81 IVIGFSLTAFFAALALQTYRRLGSVDLRQIDAAERLGSPT 120
Cdd:PRK12658  81 IVIGFGLLAFLLVLAYRAYQDLGTDDTDEMRVAEPVEEPL 120
PRK09094 PRK09094
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-104 2.43e-30

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236377  Cd Length: 114  Bit Score: 104.96  E-value: 2.43e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIRAGESSLPADAANPLPQALVLTA 80
Cdd:PRK09094   1 MELVLALAIGVLTASGVWLLLRPRTFQVILGLSLLSYAVNLFIFAMGRLRVGAPPVLQPGVPVDLANYTDPLPQALVLTA 80

                         90       100
                 ....*....|....*....|....
gi 500264322  81 IVIGFSLTAFFAALALQTYRRLGS 104
Cdd:PRK09094  81 IVIGFAMTALFLVVALASRGLTGT 104
PRK12659 PRK12659
Na+/H+ antiporter subunit C;
1-116 1.62e-25

Na+/H+ antiporter subunit C;


Pssm-ID: 183659  Cd Length: 117  Bit Score: 92.80  E-value: 1.62e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIRAGESSLPADAANPLPQALVLTA 80
Cdd:PRK12659   1 MEFLLAIVVGGLYAAGIYMMLRRSIVKLVIGLILLGNAANLLIFTVGRLTRGAPPLVPEGATAPAGPVADPLPQALILTA 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 500264322  81 IVIGFSLTAFFAALALQTYRRLGSVDLRQIDAAERL 116
Cdd:PRK12659  81 IVIGFGVQAFAIVLIKRAYQVVGTDDLDEMKTTDTL 116
PRK08600 PRK08600
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-109 1.96e-25

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 181497  Cd Length: 113  Bit Score: 92.33  E-value: 1.96e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIRAGESSLpadaANPLPQALVLTA 80
Cdd:PRK08600   1 MEILMIIVIGILTAIAVYLILSKSLLRIIIGTTLLSHGANLLLLTMGGLKKGAVPILGEGVTSY----VDPLPQALILTA 76

                         90       100
                 ....*....|....*....|....*....
gi 500264322  81 IVIGFSLTAFFAALALQTYRRLGSVDLRQ 109
Cdd:PRK08600  77 IVISFGVTAFFLVLAYRTYKELGTDNVEQ 105
2a6301s03 TIGR00941
Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and ...
 1-107 1.45e-19

Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273354  Cd Length: 104  Bit Score: 77.15  E-value: 1.45e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322    1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIRAGESSLpadaANPLPQALVLTA 80
Cdd:TIGR00941   1 MESIFALIIGILTASGVYLLLSRSVVRVVLGLALLGYAVNLFILTMGGLENKAPPILTLPVGPY----VDPLPQALILTA 76

                          90       100
                  ....*....|....*....|....*..
gi 500264322   81 IVIGFSLTAFFAALALQTYRRLGSVDL 107
Cdd:TIGR00941  77 IVIGFATTALFLVVALRAYQVAGTDDV 103
PRK12660 PRK12660
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-107 2.93e-19

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 183660  Cd Length: 114  Bit Score: 76.70  E-value: 2.93e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIRAGESSLPADaanPLPQALVLTA 80
Cdd:PRK12660   1 MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGGYGSSRSEPLITGGNQLFVD---PLLQAIVLTA 77

                         90       100
                 ....*....|....*....|....*..
gi 500264322  81 IVIGFSLTAFFAALALQTYRRLGSVDL 107
Cdd:PRK12660  78 IVIGFGMTAFLLVLVYRTYKVTKEDEI 104
PRK07946 PRK07946
putative monovalent cation/H+ antiporter subunit C; Reviewed
 3-127 3.46e-19

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236136  Cd Length: 163  Bit Score: 77.78  E-value: 3.46e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   3 LLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPavIRAGESSLPADAANPLPQALVLTAIV 82
Cdd:PRK07946   5 LGLLVAIGVLTSAGVYLLLERSLTRMLLGLLLIGNGVNLLILTAGGPAGNPP--ILGRTSEYGETMADPLAQAMILTAIV 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 500264322  83 IGFSLTAFFAALALQTYRRLG----SVDLRQIDAAERLGSPTSAGKDRP 127
Cdd:PRK07946  83 ITMGITAFVLALAYRSYRLTTadevEDDPEDTRVALRRRGLASAAPDHD 131
PRK07375 PRK07375
Na+/H+ antiporter subunit C;
1-111 9.00e-18

Na+/H+ antiporter subunit C;


Pssm-ID: 236004  Cd Length: 112  Bit Score: 73.00  E-value: 9.00e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   1 MHLLFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIRageSSLPADAANPLPQALVLTA 80
Cdd:PRK07375   2 QLMIYALAIALLVIGLYGLIFKRNLLKKIIGLDVFQTGVNLFYIAIGYRSGGGVPILS---PSGFTTYADPLPQALVLTA 78

                         90       100       110
                 ....*....|....*....|....*....|.
gi 500264322  81 IVIGFSLTAFFAALALQTYRRLGSVDLRQID 111
Cdd:PRK07375  79 IVIGFATTAVMLALIVKLYKDYGTLSESEIE 109
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-115 8.38e-12

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 57.19  E-value: 8.38e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322    4 LFALSIAVLAGCSLYLIL-SRHIVRVLLGVTMLSAAINLVIFFAGRIvtntpaviragesslpadAANPLPQALVLTAIV 82
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLlRRNLLRVLLSLELMLNAVNLALVLFGRL------------------TADPLPQALILTAIV 62

                          90       100       110
                  ....*....|....*....|....*....|...
gi 500264322   83 IGFSLTAFFAALALQTYRRLGSVDLRQIDAAER 115
Cdd:pfam00420  63 IAAAEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
PRK12661 PRK12661
putative monovalent cation/H+ antiporter subunit C; Reviewed
 4-110 1.01e-11

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 237162  Cd Length: 140  Bit Score: 57.86  E-value: 1.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322   4 LFALSIAVLAGCSLYLILSRHIVRVLLGVTMLSAAINLVIFFAGRIV-TNTPAVIRAGESSLPADA-------------- 68
Cdd:PRK12661   5 FLSLTIALLFGIGTFLILRRDMIKVIIGLSIISHAVNLLIVSSGVFEgTKVPIITEQGHEGSGSGIiyndnltsgilapi 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 500264322  69 ---------ANPLPQALVLTAIVIGFSLTAFFAALALQTYRRLGSVDLRQI 110
Cdd:PRK12661  85 vtngpetefVDPLVQALVLTAIVIGLATTAFILILAYRIYEEYGTTDIREL 135
PRK08388 PRK08388
putative monovalent cation/H+ antiporter subunit C; Reviewed
 19-110 7.59e-09

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236257  Cd Length: 119  Bit Score: 49.90  E-value: 7.59e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322  19 LILSRHIVRVLLGVTMLSAAINLVIFFAG-RIVTNTP--AVIRAGESSLPADAANPLPQALVLTAIVIGFSLTAFFAALA 95
Cdd:PRK08388  20 FLYKRNLIKLILALDLIDSGIHLLLISLGyRMENGLPptAPIYTGYETLKSPMVGPIPQALVLTSIVIGVCVLSLAMALT 99

                         90
                 ....*....|....*
gi 500264322  96 LQTYRRLGSVDLRQI 110
Cdd:PRK08388 100 INAYRHYGTLDVTKL 114
PRK08389 PRK08389
putative monovalent cation/H+ antiporter subunit C; Reviewed
 19-110 1.32e-08

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236258  Cd Length: 114  Bit Score: 49.35  E-value: 1.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500264322  19 LILSRHIVRVLLGVTMLSAAINLVIFFAGRIVTNTPAVIRAGESslPADAANPLPQALVLTAIVIGFSLTAFFAALALQT 98
Cdd:PRK08389  20 VLVKKNLLKIIIGLDIMETGVNLLLISIGYVSGRSAPILSEGIT--PSNYVDPIPQALVLTAIVIGVSTTALALSVAIKL 97

                         90
                 ....*....|..
gi 500264322  99 YRRLGSVDLRQI 110
Cdd:PRK08389  98 YEKYGTLNVEEI 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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