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Conserved domains on  [gi|501043650|ref|WP_012095504|]
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MULTISPECIES: nucleotide exchange factor GrpE [Bacillus cereus group]

Protein Classification

nucleotide exchange factor GrpE( domain architecture ID 10793973)

nucleotide exchange factor GrpE functions as a nucleotide exchange factor for DnaK and participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may also function as a thermosensor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK14140 PRK14140
heat shock protein GrpE; Provisional
 1-198 1.10e-85

heat shock protein GrpE; Provisional


:

Pssm-ID: 237622 [Multi-domain]  Cd Length: 191  Bit Score: 250.69  E-value: 1.10e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   1 MEERNEQVVEETKEAQTEEATIEKNSEESVTEEATEetvveekSEAALLQEKVDELQAKLTETEGRMLRLQADFENYKRR 80
Cdd:PRK14140   1 MEEKNEQVEEEVEETEVEEAVEDEVEEETVEEESEA-------ELLDEEQAKIAELEAKLDELEERYLRLQADFENYKRR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  81 VQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQA 160
Cdd:PRK14140  74 IQKENEAAEKYRAQSLASDLLPALDNFERALQIEADDEQTKSLLKGVEMVHRQLLEALKKEGVEVIEAVGEQFDPNLHQA 153

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 501043650 161 VMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:PRK14140 154 VMQDEDEDFESNEVVEELQKGYKLKDRVIRPSMVKVNQ 191
 
Name Accession Description Interval E-value
PRK14140 PRK14140
heat shock protein GrpE; Provisional
 1-198 1.10e-85

heat shock protein GrpE; Provisional


Pssm-ID: 237622 [Multi-domain]  Cd Length: 191  Bit Score: 250.69  E-value: 1.10e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   1 MEERNEQVVEETKEAQTEEATIEKNSEESVTEEATEetvveekSEAALLQEKVDELQAKLTETEGRMLRLQADFENYKRR 80
Cdd:PRK14140   1 MEEKNEQVEEEVEETEVEEAVEDEVEEETVEEESEA-------ELLDEEQAKIAELEAKLDELEERYLRLQADFENYKRR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  81 VQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQA 160
Cdd:PRK14140  74 IQKENEAAEKYRAQSLASDLLPALDNFERALQIEADDEQTKSLLKGVEMVHRQLLEALKKEGVEVIEAVGEQFDPNLHQA 153

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 501043650 161 VMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:PRK14140 154 VMQDEDEDFESNEVVEELQKGYKLKDRVIRPSMVKVNQ 191
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 54-198 2.71e-59

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 182.27  E-value: 2.71e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  54 DELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQ 133
Cdd:COG0576    2 EELEAELAELKDRLLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAAEEDEDVKSLLEGVEMTLKQ 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 501043650 134 LLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:COG0576   82 LLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVEPGTVVEVLQKGYRLGDRVLRPAMVVVAK 146
GrpE cd00446
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 62-196 3.61e-56

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


Pssm-ID: 271355 [Multi-domain]  Cd Length: 136  Bit Score: 173.85  E-value: 3.61e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  62 ETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQLLEALNKE 141
Cdd:cd00446    2 ELKDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEAAPKEEELKNLLEGVEMTLKQLLKVLEKH 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 501043650 142 GVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:cd00446   82 GVEEIEPEGEKFDPNLHEAVMQVESPDKEPGTVVEVLQKGYKLHDRVLRPAMVVV 136
GrpE pfam01025
GrpE;
45-198 1.07e-51

GrpE;


Pssm-ID: 425996 [Multi-domain]  Cd Length: 165  Bit Score: 163.55  E-value: 1.07e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   45 EAALLQEKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLL 124
Cdd:pfam01025  12 EIESLEEEIEELEKKIEELKEKLLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNSAPENEDVKSLL 91

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 501043650  125 QGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:pfam01025  92 EGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKPEGTVVEVLQKGYKLHDRVLRPAMVVVSK 165
 
Name Accession Description Interval E-value
PRK14140 PRK14140
heat shock protein GrpE; Provisional
 1-198 1.10e-85

heat shock protein GrpE; Provisional


Pssm-ID: 237622 [Multi-domain]  Cd Length: 191  Bit Score: 250.69  E-value: 1.10e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   1 MEERNEQVVEETKEAQTEEATIEKNSEESVTEEATEetvveekSEAALLQEKVDELQAKLTETEGRMLRLQADFENYKRR 80
Cdd:PRK14140   1 MEEKNEQVEEEVEETEVEEAVEDEVEEETVEEESEA-------ELLDEEQAKIAELEAKLDELEERYLRLQADFENYKRR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  81 VQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQA 160
Cdd:PRK14140  74 IQKENEAAEKYRAQSLASDLLPALDNFERALQIEADDEQTKSLLKGVEMVHRQLLEALKKEGVEVIEAVGEQFDPNLHQA 153

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 501043650 161 VMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:PRK14140 154 VMQDEDEDFESNEVVEELQKGYKLKDRVIRPSMVKVNQ 191
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 54-198 2.71e-59

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 182.27  E-value: 2.71e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  54 DELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQ 133
Cdd:COG0576    2 EELEAELAELKDRLLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAAEEDEDVKSLLEGVEMTLKQ 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 501043650 134 LLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:COG0576   82 LLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVEPGTVVEVLQKGYRLGDRVLRPAMVVVAK 146
GrpE cd00446
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 62-196 3.61e-56

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


Pssm-ID: 271355 [Multi-domain]  Cd Length: 136  Bit Score: 173.85  E-value: 3.61e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  62 ETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQLLEALNKE 141
Cdd:cd00446    2 ELKDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEAAPKEEELKNLLEGVEMTLKQLLKVLEKH 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 501043650 142 GVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:cd00446   82 GVEEIEPEGEKFDPNLHEAVMQVESPDKEPGTVVEVLQKGYKLHDRVLRPAMVVV 136
GrpE pfam01025
GrpE;
45-198 1.07e-51

GrpE;


Pssm-ID: 425996 [Multi-domain]  Cd Length: 165  Bit Score: 163.55  E-value: 1.07e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   45 EAALLQEKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLL 124
Cdd:pfam01025  12 EIESLEEEIEELEKKIEELKEKLLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNSAPENEDVKSLL 91

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 501043650  125 QGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:pfam01025  92 EGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKPEGTVVEVLQKGYKLHDRVLRPAMVVVSK 165
PRK14162 PRK14162
heat shock protein GrpE; Provisional
 2-198 3.90e-33

heat shock protein GrpE; Provisional


Pssm-ID: 237631 [Multi-domain]  Cd Length: 194  Bit Score: 117.24  E-value: 3.90e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   2 EERNEQVVEETKEAQTEEATIEKnseesvteeateetVVEEKSEAALLQEKVDELQAKLTETEGRMLRLQADFENYKRRV 81
Cdd:PRK14162  11 DLPQEETTDEAPKKEAKEAPKEE--------------DQEKQNPVEDLEKEIADLKAKNKDLEDKYLRSQAEIQNMQNRY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  82 QLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAV 161
Cdd:PRK14162  77 AKERAQLIKYESQSLAKDVLPAMDNLERALAVKADDEAAKQLKKGVQMTLDHLVKALKDHGVTEIKADGEKFDPTLHQAV 156

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 501043650 162 MQVE-DSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:PRK14162 157 QTVAaENDDQKDHVVQVLQKGYQYKDRTLRPAMVVVAQ 194
PRK14158 PRK14158
heat shock protein GrpE; Provisional
 44-196 5.62e-32

heat shock protein GrpE; Provisional


Pssm-ID: 172646 [Multi-domain]  Cd Length: 194  Bit Score: 114.26  E-value: 5.62e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  44 SEAALLQEKVDELQAKLTETEG---RMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQvEASDEQT 120
Cdd:PRK14158  37 AAADRIKELEEALAAKEAEAAAnwdKYLRERADLENYRKRVQKEKEELLKYGNESLILEILPAVDNMERALD-HADEESM 115

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 501043650 121 KSLLQGMEMVYRQLLEALNKEGVEMIEA-VGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14158 116 SAIIEGIRMTLSMLLSTLKKFGVTPVEAeKGTPFDPAYHQAMCQVESAEQEPNTVVAVFQKGYLLNERLLRPAMVSV 192
PRK14150 PRK14150
heat shock protein GrpE; Provisional
 5-198 2.11e-31

heat shock protein GrpE; Provisional


Pssm-ID: 184539 [Multi-domain]  Cd Length: 193  Bit Score: 112.71  E-value: 2.11e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   5 NEQVVEETKEAQTEEATIEKNSEEsvteeateetvveekSEAALLQEKVDELQAKLTETEGR----MLRLQADFENYKRR 80
Cdd:PRK14150  10 QEQVSEEIEAEVEQQEEADEAELE---------------DELDEADARIAELEAQLAEAQAEerdsVLRARAEVENIRRR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  81 VQLDKQAAEKYRAQSLVSDILPALDNFERAMQV-EASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQ 159
Cdd:PRK14150  75 AEQDVEKAHKFALEKFANELLPVIDNLERALQAaDKENEALKALIEGVELTLKSLLDTVAKFGVEVVGPVGEPFNPEVHQ 154

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 501043650 160 AVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:PRK14150 155 AISMQESEDHEPNTVMMVMQKGYTLNGRLLRPAMVMVSK 193
PRK14143 PRK14143
heat shock protein GrpE; Provisional
 5-196 6.16e-31

heat shock protein GrpE; Provisional


Pssm-ID: 237624 [Multi-domain]  Cd Length: 238  Bit Score: 112.90  E-value: 6.16e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   5 NEQVVEETKEAQTEEATIEKNSEESVTEEATEETVVEEKSEAAL--LQEKVDELQAKLTETEGRMLRLQADFENYKRRVQ 82
Cdd:PRK14143  26 ESSEEVTEQEAELTNPEGDAAEAESSPDSGSAASETAADNAARLaqLEQELESLKQELEELNSQYMRIAADFDNFRKRTS 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  83 LDKQAAEKYRAQSLVSDILPALDNFERA-MQVEASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAV 161
Cdd:PRK14143 106 REQEDLRLQLKCNTLSEILPVVDNFERArQQLKPEGEEAQALHRSYQGLYKQLVDVLKRLGVSPMRVVGQEFDPNLHEAV 185

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 501043650 162 MQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14143 186 LREPSDEHPEDVVLEELQRGYHLGGRVLRHAMVKV 220
PRK14141 PRK14141
heat shock protein GrpE; Provisional
 56-196 6.42e-31

heat shock protein GrpE; Provisional


Pssm-ID: 172630  Cd Length: 209  Bit Score: 112.07  E-value: 6.42e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  56 LQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQV------EASDEQTKSLLQGMEM 129
Cdd:PRK14141  43 LKAENAELKDRMLRLAAEMENLRKRTQRDVADARAYGIAGFARDMLSVSDNLRRALDAipaearAAADAGLKALIEGVEM 122

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 501043650 130 VYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14141 123 TERAMLNALERHGVKKLDPEGQKFDPNFHQAMFEVPNPDVPNNTVVQVVQAGYTIGERVLRPAMVGV 189
PRK14153 PRK14153
heat shock protein GrpE; Provisional
 13-198 7.32e-31

heat shock protein GrpE; Provisional


Pssm-ID: 184540 [Multi-domain]  Cd Length: 194  Bit Score: 111.47  E-value: 7.32e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  13 KEAQTEEATIEKNSEESVTEEATEETVVEEKSEAALLQEKVDELQAKLtetegrmLRLQADFENYKRRVQLDKQAAEKYR 92
Cdd:PRK14153   9 DKAENSEARNSGSSAEEAEELKEEPEDSTADSETEKCREEIESLKEQL-------FRLAAEFDNFRKRTAREMEENRKFV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  93 AQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESN 172
Cdd:PRK14153  82 LEQVLLDLLEVTDNFERALESARTAEDMNSIVEGIEMVSKQFFSILEKYGLERIECEGEEFDPHRHEAMMHVETSEVPDN 161

                        170       180
                 ....*....|....*....|....*.
gi 501043650 173 AVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:PRK14153 162 TIVDVCKPGYALNSKVIRPAMVSVAR 187
PRK14160 PRK14160
heat shock protein GrpE; Provisional
 2-196 2.11e-30

heat shock protein GrpE; Provisional


Pssm-ID: 237629 [Multi-domain]  Cd Length: 211  Bit Score: 110.61  E-value: 2.11e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   2 EERNEQVVEET-KEAQTEEATIEKNSEESVTEEATEETVVEEKSEAALLQEKVDELQAKLTETEGRMLRLQADFENYKRR 80
Cdd:PRK14160  18 CKENENKEEDKgKEEDLEFEEIEKEEIIEDSEESNEVKIEELKDENNKLKEENKKLENELEALKDRLLRTVAEYDNYRKR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  81 VQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKsllQGMEMVYRQLLEALNKEGVEMIEAVGKqFDPHEHQA 160
Cdd:PRK14160  98 TAKEKEGIYSDACEDVLKELLPVLDNLERAAAVEGSVEDLK---KGIEMTVKQFKTSLEKLGVEEISTEGE-FDPNLHNA 173

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 501043650 161 VMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14160 174 VMHVEDENYGENEIVEVFQKGYKRGDKVIRYSMVKV 209
PRK14139 PRK14139
heat shock protein GrpE; Provisional
 1-198 2.03e-29

heat shock protein GrpE; Provisional


Pssm-ID: 237621 [Multi-domain]  Cd Length: 185  Bit Score: 107.37  E-value: 2.03e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   1 MEERNEQVVEETKEAQTEEATIEKNSEESVTeeateetvveekSEAALLQEKVDELQAKLTETEGRMLRLQADFENYKRR 80
Cdd:PRK14139   1 MENTQQNPSEQEAEEAGAAAQAAAAAAAAAE------------DAAPALEAELAEAEAKAAELQDSFLRAKAETENVRRR 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  81 VQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQtkSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQA 160
Cdd:PRK14139  69 AQEDVAKAHKFAIESFAESLLPVKDSLEAALADESGDLE--KLREGVELTLKQLTSAFEKGRVVEINPVGEKFDPHQHQA 146

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 501043650 161 VMQVEdSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:PRK14139 147 ISMVP-AEQEPNTVVAVLQKGYTIADRVLRPALVTVAA 183
PRK14151 PRK14151
heat shock protein GrpE; Provisional
 49-198 1.33e-28

heat shock protein GrpE; Provisional


Pssm-ID: 172640 [Multi-domain]  Cd Length: 176  Bit Score: 104.86  E-value: 1.33e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  49 LQEKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQV-EASDEQTKSLLQGM 127
Cdd:PRK14151  25 LTARVQELEEQLAAAKDQSLRAAADLQNVRRRAEQDVEKAHKFALEKFAGDLLPVVDSLERGLELsSADDEAIKPMREGV 104

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 501043650 128 EMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:PRK14151 105 ELTLKMFQDTLKRYQLEAVDPHGEPFNPEHHQAMAMQESADVEPNSVLKVFQKGYLLNGRLLRPAMVVVSK 175
PRK14149 PRK14149
heat shock protein GrpE; Provisional
 13-196 2.58e-28

heat shock protein GrpE; Provisional


Pssm-ID: 184538 [Multi-domain]  Cd Length: 191  Bit Score: 104.57  E-value: 2.58e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  13 KEAQTEEATIEKNSEESVTEEATEETVVEEKSEAALL-QEKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKY 91
Cdd:PRK14149   4 EHNQEHDHLSQKEPESEEKACACKEQQGEEKQEASEKeGEIKEDFELKYKEMHEKYLRVHADFENVKKRLERDKSMALEY 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  92 RAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGkQFDPHEHQAVMQVEDSEFES 171
Cdd:PRK14149  84 AYEKIALDLLPVIDALLGALKSAAEVDKESALTKGLELTMEKLHEVLARHGIEGIECLE-EFDPNFHNAIMQVKSEEKEN 162

                        170       180
                 ....*....|....*....|....*
gi 501043650 172 NAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14149 163 GKIVQVLQQGYKYKGRVLRPAMVSI 187
PRK14147 PRK14147
heat shock protein GrpE; Provisional
 45-196 4.32e-27

heat shock protein GrpE; Provisional


Pssm-ID: 237625 [Multi-domain]  Cd Length: 172  Bit Score: 101.18  E-value: 4.32e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  45 EAALLQEKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQveASDEQTKSLL 124
Cdd:PRK14147  19 ETDPLKAEVESLRSEIALVKADALRERADLENQRKRIARDVEQARKFANEKLLGELLPVFDSLDAGLT--AAGTEPSPLR 96

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 501043650 125 QGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14147  97 DGLELTYKQLLKVAADNGLTLLDPVGQPFNPEHHQAISQGEAEGVAPGHVVQVFQKGYLLNERLLRPALVVV 168
PRK14155 PRK14155
heat shock protein GrpE; Provisional
 45-196 2.89e-26

heat shock protein GrpE; Provisional


Pssm-ID: 237627 [Multi-domain]  Cd Length: 208  Bit Score: 100.04  E-value: 2.89e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  45 EAALLQEKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQ---TK 121
Cdd:PRK14155  14 EADDAAQEIEALKAEVAALKDQALRYAAEAENTKRRAEREMNDARAYAIQKFARDLLGAADNLGRATAASPKDSAdpaVK 93

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 501043650 122 SLLQGMEMVYRQLLEALNKEGVEMIE-AVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14155  94 NFIIGVEMTEKELLGAFERNGLKKIDpAKGDKFDPHLHQAMMEQPSTEVAAGGVLQVMQAGYELMGRLVRPAMVAV 169
PRK14145 PRK14145
heat shock protein GrpE; Provisional
 10-196 8.70e-26

heat shock protein GrpE; Provisional


Pssm-ID: 184536 [Multi-domain]  Cd Length: 196  Bit Score: 98.45  E-value: 8.70e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  10 EETKEAQTEEATIEKNSEESVTEEATEETVVEEKSEAALLQEKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAE 89
Cdd:PRK14145  11 EEEKDVNNLSSNEQMEGPPEDEQAQQNQPQQQTVDEIEELKQKLQQKEVEAQEYLDIAQRLKAEFENYRKRTEKEKSEMV 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  90 KYRAQSLVSDILPALDNFERAMqveASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEF 169
Cdd:PRK14145  91 EYGKEQVILELLPVMDNFERAL---ASSGDYNSLKEGIELIYRQFKKILDKFGVKEIEAEGQIFDPYKHHAVMQEEVEGK 167

                        170       180
                 ....*....|....*....|....*..
gi 501043650 170 ESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14145 168 QPNEIIEVFQKGYYLKDKVIRPSLVKV 194
PRK14144 PRK14144
heat shock protein GrpE; Provisional
 1-198 1.73e-25

heat shock protein GrpE; Provisional


Pssm-ID: 184535 [Multi-domain]  Cd Length: 199  Bit Score: 97.87  E-value: 1.73e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   1 MEERNEQVVEETKEAQTEEATIEKNSEESVTEEATEETvveeksEAALLQEKVDELQAKLTETEG-------RMLRLQAD 73
Cdd:PRK14144   1 MSKQNKKDWKKFKDEHKEEHKVENEILEEETDEESQHQ------EPALGHPSYTALEEQLTLAEQkahenweKSVRALAE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  74 FENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVeASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQF 153
Cdd:PRK14144  75 LENVRRRMEREVANAHKYGVEKLISALLPVVDSLEQALQL-ADKNSDPSMHEGLELTMKLFLDALQKFDVEQIDPLGQTF 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 501043650 154 DPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:PRK14144 154 DPQQHEAMSMQPAPGAPPNSVITVFQKGYKLSDRVIRPARVIVST 198
PRK10325 PRK10325
heat shock protein GrpE; Provisional
 51-196 7.78e-24

heat shock protein GrpE; Provisional


Pssm-ID: 182379 [Multi-domain]  Cd Length: 197  Bit Score: 93.20  E-value: 7.78e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  51 EKVDELQAKLTETEGR----MLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQV-EASDEQTKSLLQ 125
Cdd:PRK10325  42 EKIANLEAQLAEAQTRerdgILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEVaDKANPDMSAMVE 121

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 501043650 126 GMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK10325 122 GIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTV 192
PRK14156 PRK14156
heat shock protein GrpE; Provisional
 2-196 3.94e-23

heat shock protein GrpE; Provisional


Pssm-ID: 237628 [Multi-domain]  Cd Length: 177  Bit Score: 91.05  E-value: 3.94e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   2 EERNEQVVEETKEAQTEEATIEKnseesvteeateETVVEEKSEAALLQEKVDELqakltetEGRMLRLQADFENYKRRV 81
Cdd:PRK14156   4 EIKNEEVEEEVEATETEETVEEV------------VEETPEKSELELANERADEF-------ENKYLRAHAEMQNIQRRA 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  82 QLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKsllQGMEMVYRQLLEALNKEGVEMIEAvgKQFDPHEHQAV 161
Cdd:PRK14156  65 NEERQQLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVK---KGLEMVQESLIQALKEEGVEEVAV--DSFDHNLHMAV 139

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 501043650 162 MQVE-DSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14156 140 QTLPaDDEHPADSIAQVFQKGYKLHERLLRPAMVVV 175
PRK14159 PRK14159
heat shock protein GrpE; Provisional
 52-196 8.31e-23

heat shock protein GrpE; Provisional


Pssm-ID: 172647 [Multi-domain]  Cd Length: 176  Bit Score: 90.13  E-value: 8.31e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  52 KVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVY 131
Cdd:PRK14159  31 EQNKLQKDYDELKDKYMRANAEFENIKKRMEKEKLSAMAYANESFAKDLLDVLDALEAAVNVECHDEISLKIKEGVQNTL 110

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 501043650 132 RQLLEALNKEGVEMIEAvGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14159 111 DLFLKKLEKHGVALIKE-EKEFDPNLHEAMFHVDSENHQSGEVVQVLQKGYKIADRVIRPTKVSV 174
PRK14163 PRK14163
heat shock protein GrpE; Provisional
 44-198 8.15e-20

heat shock protein GrpE; Provisional


Pssm-ID: 184546 [Multi-domain]  Cd Length: 214  Bit Score: 83.25  E-value: 8.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  44 SEAALLQEKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAmqveasdEQTKSL 123
Cdd:PRK14163  40 AATAGLTAQLDQVRTALGERTADLQRLQAEYQNYRRRVERDRVTVKEIAVANLLSELLPVLDDVGRA-------REHGEL 112

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 501043650 124 LQGMEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKVNQ 198
Cdd:PRK14163 113 VGGFKSVAESLETTVAKLGLQQFGKEGEPFDPTIHEALMHSYAPDVTETTCVAILQPGYRIGERTIRPARVAVAE 187
PRK14148 PRK14148
heat shock protein GrpE; Provisional
 50-196 3.25e-19

heat shock protein GrpE; Provisional


Pssm-ID: 172637 [Multi-domain]  Cd Length: 195  Bit Score: 81.34  E-value: 3.25e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  50 QEKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEM 129
Cdd:PRK14148  46 KDTIKELEDSCDQFKDEALRAKAEMENIRKRAERDVSNARKFGIEKFAKELLPVIDSIEQALKHEVKLEEAIAMKEGIEL 125

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 501043650 130 VYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14148 126 TAKMLVDILKKNGVEELDPKGEKFDPNLHEAMAMIPNPEFEDNTIFDVFQKGYMLNGRIVRAAKVVI 192
PRK14146 PRK14146
heat shock protein GrpE; Provisional
 2-198 4.81e-18

heat shock protein GrpE; Provisional


Pssm-ID: 172635 [Multi-domain]  Cd Length: 215  Bit Score: 78.62  E-value: 4.81e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   2 EERNEQVVEETK--EAQTEEATIEKNSEESVTEEATEETVVEEKSEAA-------LLQEKVDELQAKLTETEGRMLRLQA 72
Cdd:PRK14146   3 ETSNNKTSEEAKanEKKSQSQTLEESKLENMNSEESQTITEETQEQAVegaetetSLQKELDNAKKEIESLKDSWARERA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  73 DFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSLLQGMEMVYRQLLEALNKEGVEMIEAVGKQ 152
Cdd:PRK14146  83 EFQNFKRRSAQEFVSIRKEAVKSLVSGFLNPIDNLERVGATQNQSEELKPFVEGVKMILKEFYSVLEKSNVIRFDPKGEP 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 501043650 153 FDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKD----RVIRPSMVKVNQ 198
Cdd:PRK14146 163 FDPMSMEALSSEEGDQYSEETVIDVYQAGYYYKEnedkFTLRPARVRIGK 212
PRK14161 PRK14161
heat shock protein GrpE; Provisional
 51-196 8.49e-17

heat shock protein GrpE; Provisional


Pssm-ID: 237630 [Multi-domain]  Cd Length: 178  Bit Score: 74.24  E-value: 8.49e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  51 EKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEA--SDEQTKSLLQGME 128
Cdd:PRK14161  26 PEITALKAEIEELKDKLIRTTAEIDNTRKRLEKARDEAKDYAIATFAKELLNVSDNLSRALAHKPanSDVEVTNIIAGVQ 105

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 501043650 129 MVYRQLLEALNKEGVEMIE-AVGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14161 106 MTKDELDKVFHKHHIEEIKpEIGSMFDYNLHNAISQIEHPDHAPNSIITLMQSGYKIRDRLLRPATVQV 174
PRK14154 PRK14154
heat shock protein GrpE; Provisional
 49-196 8.10e-16

heat shock protein GrpE; Provisional


Pssm-ID: 237626 [Multi-domain]  Cd Length: 208  Bit Score: 72.54  E-value: 8.10e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  49 LQEKVDELQAKLTETEGRMLRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEAS-DEQTKSLLQGM 127
Cdd:PRK14154  57 LEGQLTRMERKVDEYKTQYLRAQAEMDNLRKRIEREKADIIKFGSKQLITDLLPVADSLIHGLESPASeDPQVKSMRDGM 136

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650 128 EMVYRQLLEALNKEGVEMIEA-VGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14154 137 SLTLDLLHNTLAKHGVQVINPnPGDPFDPALHEAMSVQAVPDAKPDTIIQVLQKGYQLNGRVLRAARVIV 206
PRK14142 PRK14142
heat shock protein GrpE; Provisional
 44-196 1.88e-15

heat shock protein GrpE; Provisional


Pssm-ID: 237623  Cd Length: 223  Bit Score: 71.57  E-value: 1.88e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  44 SEAALLQEKVDELQAKLTetegrmlRLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMqvEASDEQTKSL 123
Cdd:PRK14142  40 ADAAHTEDKVAELTADLQ-------RVQADFANYRKRALRDQQAAADRAKASVVSQLLGVLDDLERAR--KHGDLESGPL 110

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 501043650 124 lqgmEMVYRQLLEALNKEGVEMIEAVGKQFDPHEHQAVMQVEDSEFESNAVVEE-FQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14142 111 ----KSVADKLDSALTGLGLVAFGAEGEDFDPVLHEAVQHEGDGGQGSKPVIGTvMRQGYQLGEQVLRHALVGV 180
PRK14164 PRK14164
heat shock protein GrpE; Provisional
 3-194 7.69e-14

heat shock protein GrpE; Provisional


Pssm-ID: 237632 [Multi-domain]  Cd Length: 218  Bit Score: 67.13  E-value: 7.69e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650   3 ERNEQVVEETKEAQ--TEEATIEKNSEESVTEEATEETVVEEKSEAALLQEKVDE--LQAKLTETEGRMLRLQADFENYK 78
Cdd:PRK14164  25 DRAEAAAEEAALAQgvPEDDPFGDAVEGEIDPDLEADLEDLLDDVDPELADDGEAstVEAQLAERTEDLQRVTAEYANYR 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  79 RRVQLDKQAAEKYRAQSLVSDILPALDNFERAmqvEASDEQTKSLLQGMEMVYRQLLEALnkeGVEMIEAVGKQFDPHEH 158
Cdd:PRK14164 105 RRTERERQAIIETAKAGVATDLLPILDDLDLA---EQHGDLNEGPLKAFSDKLTNVLAGL---KVEKFGEEGDAFDPEIH 178

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 501043650 159 QAVMQVedSEFESNAVVEEFQKGYKLKDRVIRPSMV 194
Cdd:PRK14164 179 EAVQDL--SSGDEKVLGTVLRKGYRMGDRVLRTAMV 212
PRK14157 PRK14157
heat shock protein GrpE; Provisional
 69-196 7.88e-11

heat shock protein GrpE; Provisional


Pssm-ID: 184543 [Multi-domain]  Cd Length: 227  Bit Score: 59.20  E-value: 7.88e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501043650  69 RLQADFENYKRRVQLDKQAAEKYRAQSLVSDILPALDNFERAMQVEASDEQTKSllqgmemVYRQLLEALNKEGVEMIEA 148
Cdd:PRK14157 102 RERAEFINYRNRTQKEQDRFRQHGIIDVLTALLPALDDIDRIREHSEMDDSFKA-------VAAKIDKAFEKFGVEKFGE 174

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 501043650 149 VGKQFDPHEHQAVMQVEDSEFESNAVVEEFQKGYKLKDRVIRPSMVKV 196
Cdd:PRK14157 175 KGEDFDPTKHDAILHKPDPDAEKETVDTVVEAGYRIGDRVIRAARVVV 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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