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Conserved domains on  [gi|501332908|ref|WP_012364543|]
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adenylate kinase [Burkholderia ambifaria]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11478412)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

CATH:  3.40.50.300
EC:  2.7.4.-
Gene Ontology:  GO:0050145|GO:0016310|GO:0046872
PubMed:  2841070
SCOP:  3002021

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 1-220 7.23e-140

adenylate kinase; Reviewed


:

Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 389.89  E-value: 7.23e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANG 80
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  81 YLFDGFPRTIAQADAM----KDAGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQR 156
Cdd:PRK00279  81 FLLDGFPRTIPQAEALdemlKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 501332908 157 DDDKEETVKKRLEVYEAQTKPLITYYGDWakrgeenglkaPQYRKISGLGTVDEIRERAFDALK 220
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKK-----------GKLKKIDGTGSIDEVFADILKALG 213
 
Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 1-220 7.23e-140

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 389.89  E-value: 7.23e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANG 80
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  81 YLFDGFPRTIAQADAM----KDAGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQR 156
Cdd:PRK00279  81 FLLDGFPRTIPQAEALdemlKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 501332908 157 DDDKEETVKKRLEVYEAQTKPLITYYGDWakrgeenglkaPQYRKISGLGTVDEIRERAFDALK 220
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKK-----------GKLKKIDGTGSIDEVFADILKALG 213
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-219 1.92e-131

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 368.30  E-value: 1.92e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANG 80
Cdd:COG0563    1 MRIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  81 YLFDGFPRTIAQADAM----KDAGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQR 156
Cdd:COG0563   81 FILDGFPRTVAQAEALdellAELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 501332908 157 DDDKEETVKKRLEVYEAQTKPLITYYGDWAKrgeenglkapqYRKISGLGTVDEIRERAFDAL 219
Cdd:COG0563  161 ADDNEETVRKRLEVYHEQTAPLIDYYRKKGK-----------LVEIDGEGSIEEVTADILAIL 212
ADK pfam00406
Adenylate kinase;
5-182 5.71e-108

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 308.08  E-value: 5.71e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908    5 LLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANGYLFD 84
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   85 GFPRTIAQADAMKD---AGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQRDDDKE 161
Cdd:pfam00406  81 GFPRTVPQAEALEElleRGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|.
gi 501332908  162 ETVKKRLEVYEAQTKPLITYY 182
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYY 181
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 2-220 5.17e-103

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 296.45  E-value: 5.17e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908    2 RLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERL-KDADCANG 80
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLtQNDDNENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   81 YLFDGFPRTIAQADAMKDAG-VAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQRDDD 159
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDALLeEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 501332908  160 KEETVKKRLEVYEAQTKPLITYYgdwAKRGeenglkapQYRKISGLGTVDEIRERAFDALK 220
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYY---KKRG--------ILVQIDGNGPIDEVWKRILEALK 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 2-211 2.27e-94

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 273.73  E-value: 2.27e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   2 RLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANGY 81
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  82 LFDGFPRTIAQA---DAMKDAGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVkfnppkveGKDDVTGEPLIQRDD 158
Cdd:cd01428   81 ILDGFPRTVDQAealDELLDEGIKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 501332908 159 DKEETVKKRLEVYEAQTKPLITYYGdwakrgeenglKAPQYRKISGLGTVDEI 211
Cdd:cd01428  153 DNEETIKKRLEVYKEQTAPLIDYYK-----------KKGKLVEIDGSGDIDEV 194
 
Name Accession Description Interval E-value
adk PRK00279
adenylate kinase; Reviewed
 1-220 7.23e-140

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 389.89  E-value: 7.23e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANG 80
Cdd:PRK00279   1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  81 YLFDGFPRTIAQADAM----KDAGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQR 156
Cdd:PRK00279  81 FLLDGFPRTIPQAEALdemlKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 501332908 157 DDDKEETVKKRLEVYEAQTKPLITYYGDWakrgeenglkaPQYRKISGLGTVDEIRERAFDALK 220
Cdd:PRK00279 161 ADDNEETVRKRLEVYHKQTAPLIDYYKKK-----------GKLKKIDGTGSIDEVFADILKALG 213
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 1-219 1.92e-131

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 368.30  E-value: 1.92e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANG 80
Cdd:COG0563    1 MRIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  81 YLFDGFPRTIAQADAM----KDAGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQR 156
Cdd:COG0563   81 FILDGFPRTVAQAEALdellAELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 501332908 157 DDDKEETVKKRLEVYEAQTKPLITYYGDWAKrgeenglkapqYRKISGLGTVDEIRERAFDAL 219
Cdd:COG0563  161 ADDNEETVRKRLEVYHEQTAPLIDYYRKKGK-----------LVEIDGEGSIEEVTADILAIL 212
ADK pfam00406
Adenylate kinase;
5-182 5.71e-108

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 308.08  E-value: 5.71e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908    5 LLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANGYLFD 84
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQNDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   85 GFPRTIAQADAMKD---AGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQRDDDKE 161
Cdd:pfam00406  81 GFPRTVPQAEALEElleRGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|.
gi 501332908  162 ETVKKRLEVYEAQTKPLITYY 182
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYY 181
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 2-220 5.17e-103

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 296.45  E-value: 5.17e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908    2 RLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERL-KDADCANG 80
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLtQNDDNENG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   81 YLFDGFPRTIAQADAMKDAG-VAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQRDDD 159
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDALLeEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 501332908  160 KEETVKKRLEVYEAQTKPLITYYgdwAKRGeenglkapQYRKISGLGTVDEIRERAFDALK 220
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYY---KKRG--------ILVQIDGNGPIDEVWKRILEALK 210
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 2-211 2.27e-94

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 273.73  E-value: 2.27e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   2 RLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANGY 81
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKGF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  82 LFDGFPRTIAQA---DAMKDAGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVkfnppkveGKDDVTGEPLIQRDD 158
Cdd:cd01428   81 ILDGFPRTVDQAealDELLDEGIKPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 501332908 159 DKEETVKKRLEVYEAQTKPLITYYGdwakrgeenglKAPQYRKISGLGTVDEI 211
Cdd:cd01428  153 DNEETIKKRLEVYKEQTAPLIDYYK-----------KKGKLVEIDGSGDIDEV 194
PLN02674 PLN02674
adenylate kinase
 2-198 1.70e-71

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 217.83  E-value: 1.70e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   2 RLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANGY 81
Cdd:PLN02674  33 RLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPSCQKGF 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  82 LFDGFPRTIAQA----DAMKDAGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQRD 157
Cdd:PLN02674 113 ILDGFPRTVVQAqkldEMLAKQGAKIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQRK 192

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 501332908 158 DDKEETVKKRLEVYEAQTKPLITYYGDWAKRGEENGLKAPQ 198
Cdd:PLN02674 193 DDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAEKPPK 233
PRK14528 PRK14528
adenylate kinase; Provisional
 2-211 5.58e-64

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 196.77  E-value: 5.58e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   2 RLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANGY 81
Cdd:PRK14528   3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIREADCKNGF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  82 LFDGFPRTIAQADA----MKDAGVAIDYVLEIDVPFSEIVERMSGRrthpasgrtyhvkfnpPKVEGkddvtgepliqRD 157
Cdd:PRK14528  83 LLDGFPRTVEQADAldalLKNEGKSIDKAINLEVPDGELLKRLLGR----------------AEIEG-----------RA 135

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 501332908 158 DDKEETVKKRLEVYEAQTKPLITYYGDWAKrgeenglkapqYRKISGLGTVDEI 211
Cdd:PRK14528 136 DDNEATIKNRLDNYNKKTLPLLDFYAAQKK-----------LSQVNGVGSLEEV 178
adk PRK02496
adenylate kinase; Provisional
 2-184 5.70e-60

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 186.49  E-value: 5.70e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   2 RLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANGY 81
Cdd:PRK02496   3 RLIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPDAANGW 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  82 LFDGFPRTIAQADA----MKDAGVAIDYVLEIDVPFSEIVERMSGRrthpasgrtyhvkfnppkvegkddvtgepliQRD 157
Cdd:PRK02496  83 ILDGFPRKVTQAAFldelLQEIGQSGERVVNLDVPDDVVVERLLAR-------------------------------GRK 131

                        170       180
                 ....*....|....*....|....*..
gi 501332908 158 DDKEETVKKRLEVYEAQTKPLITYYGD 184
Cdd:PRK02496 132 DDTEEVIRRRLEVYREQTAPLIDYYRD 158
PRK14530 PRK14530
adenylate kinase; Provisional
 2-197 8.89e-60

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 186.92  E-value: 8.89e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   2 RLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRA-AVKAGSPLGVE---AKGYMDAGKLVPDALIIGLVKERLKDADc 77
Cdd:PRK14530   5 RILLLGAPGAGKGTQSSNLAEEFGVEHVTTGDALRAnKQMDISDMDTEydtPGEYMDAGELVPDAVVNEIVEEALSDAD- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  78 anGYLFDGFPRTIAQADAMKDAgVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQRD 157
Cdd:PRK14530  84 --GFVLDGYPRNLEQAEYLESI-TDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGGELIQRD 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 501332908 158 DDKEETVKKRLEVYEAQTKPLITYYGDWAKRGEENGLKAP 197
Cdd:PRK14530 161 DDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTP 200
PLN02842 PLN02842
nucleotide kinase
 7-205 1.09e-49

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 168.89  E-value: 1.09e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   7 GAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDAD-CANGYLFDG 85
Cdd:PLN02842   4 GAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDaKEKGWLLDG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  86 FPRTIAQADAMKDAGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPkvegKDDVTGEPLIQRDDDKEETVK 165
Cdd:PLN02842  84 YPRSFAQAQSLEKLKIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFPP----ESEEIKARLITRPDDTEEKVK 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 501332908 166 KRLEVYEAQTKPLITYYGDWAKRGEENGLKAPQYRKISGL 205
Cdd:PLN02842 160 ARLQIYKKNAEAILSTYSDIMVKIDGNRPKEVVFEEISSL 199
PRK14532 PRK14532
adenylate kinase; Provisional
 1-211 1.22e-49

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 159.99  E-value: 1.22e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANG 80
Cdd:PRK14532   1 MNLILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLPEAEAAGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  81 YLFDGFPRTIAQADA----MKDAGVAIDYVLEIDVPFSEIVERMSGRrtHPASGRTyhvkfnppkvegkddvtgepliqr 156
Cdd:PRK14532  81 AIFDGFPRTVAQAEAldkmLASRGQKIDVVIRLKVDDEALIERIVKR--FEEQGRP------------------------ 134

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 501332908 157 dDDKEETVKKRLEVYEAQTKPLITYYGDWAKRGEenglkapqyrkISGLGTVDEI 211
Cdd:PRK14532 135 -DDNPEVFVTRLDAYNAQTAPLLPYYAGQGKLTE-----------VDGMGSIEAV 177
PRK14527 PRK14527
adenylate kinase; Provisional
 3-219 2.97e-49

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 159.18  E-value: 2.97e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   3 LILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADcANGYL 82
Cdd:PRK14527   9 VIFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGME-PVRVI 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  83 FDGFPRTIAQADA----MKDAGVAIDYVLEIDVPFSEIVERMSGRRTHPasgrtyhvkfnppkvegkddvtgepliQRDD 158
Cdd:PRK14527  88 FDGFPRTLAQAEAldrlLEELGARLLAVVLLEVPDEELIRRIVERARQE---------------------------GRSD 140

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 501332908 159 DKEETVKKRLEVYEAQTKPLITYYgdwAKRGeenglkapQYRKISGLGTVDEIRERAFDAL 219
Cdd:PRK14527 141 DNEETVRRRQQVYREQTQPLVDYY---EARG--------HLKRVDGLGTPDEVYARILKAL 190
PRK13808 PRK13808
adenylate kinase; Provisional
 1-184 1.66e-47

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 159.28  E-value: 1.66e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANG 80
Cdd:PRK13808   1 MRLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAANG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  81 YLFDGFPRTIAQADA----MKDAGVAIDYVLEIDVPFSEIVERMSgRRTHPASGRtyhvkfnppkvegkddvtGEPLiqR 156
Cdd:PRK13808  81 FILDGFPRTVPQAEAldalLKDKQLKLDAVVELRVNEGALLARVE-TRVAEMRAR------------------GEEV--R 139

                        170       180
                 ....*....|....*....|....*...
gi 501332908 157 DDDKEETVKKRLEVYEAQTKPLITYYGD 184
Cdd:PRK13808 140 ADDTPEVLAKRLASYRAQTEPLVHYYSE 167
PRK14531 PRK14531
adenylate kinase; Provisional
 2-214 1.79e-42

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 141.49  E-value: 1.79e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   2 RLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKdADCANGY 81
Cdd:PRK14531   4 RLLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLK-ALNSGGW 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  82 LFDGFPRTIAQADAMK----DAGVAIDYVLEIDVPFSEIVERMSGRrthpasgrtyhvkfnppkvegkddvtgepliQRD 157
Cdd:PRK14531  83 LLDGFPRTVAQAEALEplleELKQPIEAVVLLELDDAVLIERLLAR-------------------------------GRA 131

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 501332908 158 DDKEETVKKRLEVYEAQTKPLITYYGDwakRGeenglkapQYRKISGLGTVDEIRER 214
Cdd:PRK14531 132 DDNEAVIRNRLEVYREKTAPLIDHYRQ---RG--------LLQSVEAQGSIEAITER 177
PRK14529 PRK14529
adenylate kinase; Provisional
 1-213 6.22e-40

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 136.39  E-value: 6.22e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADcANG 80
Cdd:PRK14529   1 MNILIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQDG-KNG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  81 YLFDGFPRTIAQA----DAMKDAGVAIDYVLEIDVPFSEIVERMSGRR------THPAsgrtyHVKFNPPKVEGKD-DVT 149
Cdd:PRK14529  80 WLLDGFPRNKVQAeklwEALQKEGMKLDYVIEILLPREVAKNRIMGRRlckndnNHPN-----NIFIDAIKPDGDVcRVC 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 501332908 150 GEPLIQRDDDK-EETVKKRLEVY---EAQTKPLITYYGDWAKRGEenglkaPQYRKISGLGTVDEIRE 213
Cdd:PRK14529 155 GGELSTRADDQdEEAINKRHDIYydtETGTLAAAYFFKDLAAKGS------TKYIELDGEGSIDEIKE 216
PLN02459 PLN02459
probable adenylate kinase
 4-182 1.09e-39

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 136.90  E-value: 1.09e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   4 ILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKD--ADCANGY 81
Cdd:PLN02459  33 VFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEAgeEEGESGF 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  82 LFDGFPRTIAQADAMKDAgVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVE-GKDDVTGEPL------- 153
Cdd:PLN02459 113 ILDGFPRTVRQAEILEGV-TDIDLVVNLKLREEVLVEKCLGRRICSECGKNFNVADIDLKGEdGRPGIVMPPLlpppeca 191

                        170       180       190
                 ....*....|....*....|....*....|..
gi 501332908 154 ---IQRDDDKEETVKKRLEVYEAQTKPLITYY 182
Cdd:PLN02459 192 sklITRADDTEEVVKARLRVYKEESQPVEDFY 223
PRK14526 PRK14526
adenylate kinase; Provisional
 1-182 1.27e-39

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 135.36  E-value: 1.27e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANG 80
Cdd:PRK14526   1 MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVEDKINTIKNNDN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  81 YLFDGFPRTIAQADA----MKDAGVaIDYVLEIDVpfseIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQR 156
Cdd:PRK14526  81 FILDGFPRNINQAKAldkfLPNIKI-INFLIDEEL----LIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQR 155

                        170       180
                 ....*....|....*....|....*.
gi 501332908 157 DDDKEETVKKRLEVYEAQTKPLITYY 182
Cdd:PRK14526 156 KDDKEESLKTRLQEYKLQTKPLIEFY 181
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 1-182 1.99e-39

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 135.31  E-value: 1.99e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDA--DCA 78
Cdd:PTZ00088   7 LKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKVtdDCF 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  79 NGYLFDGFPRTIAQAdamKDAGV--AIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHV------KFN-PPKVEGKDDVT 149
Cdd:PTZ00088  87 KGFILDGFPRNLKQC---KELGKitNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIahirsdPYDmPPILPPADCEG 163

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 501332908 150 --GEP-LIQRDDDKEETVKKRLEVYEAQTKPLITYY 182
Cdd:PTZ00088 164 ckGNPkLQKRSDDTEEIVAHRLNTYESTNSPIIQFF 199
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 3-213 5.71e-35

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 122.48  E-value: 5.71e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908    3 LILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKA-GSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANGY 81
Cdd:TIGR01359   2 VFVLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIKReGSENGSLIESYIKEGKIVPSEVTVELLKKAIQEDGSSKKF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   82 LFDGFPRTIAQADA---MKDAGVAIDYVLEIDVPFSEIVERMSGRRThpASGRTyhvkfnppkvegkddvtgepliqrdD 158
Cdd:TIGR01359  82 LIDGFPRNEENLEAwekLMDNKVNFKFVLFFDCPEETMIKRLLKRGQ--TSGRV-------------------------D 134

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 501332908  159 DKEETVKKRLEVYEAQTKPLITYYGdwakrgeenglKAPQYRKISGLGTVDEIRE 213
Cdd:TIGR01359 135 DNIETLKKRFRTYNEETLPIIEHFE-----------NKGKVKEINAEGSVEEVFE 178
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 5-211 2.27e-32

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 115.68  E-value: 2.27e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908    5 LLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKER-LKDADCANGYLF 83
Cdd:TIGR01360   8 IVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLLKDAmVAALGTSKGFLI 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   84 DGFPRTIAQADAMKDAGVAIDYVLEIDVPFSEIVERMSGRRThpASGrtyhvkfnppkvegkddvtgepliqRDDDKEET 163
Cdd:TIGR01360  88 DGYPREVKQGEEFERRIGPPTLVLYFDCSEDTMVKRLLKRAE--TSG-------------------------RVDDNEKT 140

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 501332908  164 VKKRLEVYEAQTKPLITYYgdwAKRGeenglkapQYRKISGLGTVDEI 211
Cdd:TIGR01360 141 IKKRLETYYKATEPVIAYY---ETKG--------KLRKINAEGTVDDV 177
AAA_17 pfam13207
AAA domain;
6-133 1.24e-27

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 101.93  E-value: 1.24e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908    6 LGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSplGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANGYLFDG 85
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERIAEEAGEGGVIVDG 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 501332908   86 FPRTIAQADAMKD------AGVAIDYVLEIDVPFSEIVERMSGRRThpaSGRTY 133
Cdd:pfam13207  79 HPRIKTPAGYLPGlpvevlRELKPDAIILLEADPEEILERRLKDRT---RGRDD 129
PLN02200 PLN02200
adenylate kinase family protein
 5-220 2.48e-26

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 101.51  E-value: 2.48e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   5 LLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADcANGYLFD 84
Cdd:PLN02200  48 VLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSD-NNKFLID 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  85 GFPRTIAQADAMKDA-GVAIDYVLEIDVPFSEIVERMSGRRthpasgrtyhvkfnppkvEGkddvtgepliqRDDDKEET 163
Cdd:PLN02200 127 GFPRTEENRIAFERIiGAEPNVVLFFDCPEEEMVKRVLNRN------------------QG-----------RVDDNIDT 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 501332908 164 VKKRLEVYEAQTKPLITYYgdwAKRGeenglkapQYRKISGLGTVDEIRER------AFDALK 220
Cdd:PLN02200 178 IKKRLKVFNALNLPVIDYY---SKKG--------KLYTINAVGTVDEIFEQvrpifaACEAMK 229
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 123-158 2.14e-20

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 80.20  E-value: 2.14e-20
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 501332908  123 RRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQRDD 158
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
1-158 5.09e-05

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 42.24  E-value: 5.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILL-GAPGAGKGtQANFIKEKFGIPQISTGDMLRAAV-KAGSPLGVEAKGYMDA---GKLVPDA---LIIGLVKERL 72
Cdd:PRK01184   1 MKIIGVvGMPGSGKG-EFSKIAREMGIPVVVMGDVIREEVkKRGLEPTDENIGKVAIdlrKELGMDAvakRTVPKIREKG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908  73 KDAdcangYLFDGFpRTIAQADAMKDAGVAIDYVLEIDVPFSEIVERMSGRrthpasGRTyhvkfnppkvegkDDV-TGE 151
Cdd:PRK01184  80 DEV-----VVIDGV-RGDAEVEYFRKEFPEDFILIAIHAPPEVRFERLKKR------GRS-------------DDPkSWE 134


                 ....*..
gi 501332908 152 PLIQRDD 158
Cdd:PRK01184 135 ELEERDE 141
COG4639 COG4639
Predicted kinase [General function prediction only];
1-123 3.13e-04

Predicted kinase [General function prediction only];


Pssm-ID: 443677 [Multi-domain]  Cd Length: 145  Bit Score: 39.43  E-value: 3.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   1 MRLILL-GAPGAGKGTqanFIKEKFGIPQ-ISTgDMLRAAVkagsplgveakgYMDAGKLVPDALIIGLVKERLKDAdCA 78
Cdd:COG4639    2 LSLVVLiGLPGSGKST---FARRLFAPTEvVSS-DDIRALL------------GGDENDQSAWGDVFQLAHEIARAR-LR 64

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 501332908  79 NGYLF--DG---FPRTIAQADAM-KDAGVAIDYVLeIDVPFSEIVERMSGR 123
Cdd:COG4639   65 AGRLTvvDAtnlQREARRRLLALaRAYGALVVAVV-LDVPLEVCLARNAAR 114
Thymidylate_kin pfam02223
Thymidylate kinase;
10-126 2.93e-03

Thymidylate kinase;


Pssm-ID: 396690  Cd Length: 184  Bit Score: 37.28  E-value: 2.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501332908   10 GAGKGTQANFIKEKF---GIPQIST--------GDMLRAAVKAGSPLGVEAKGYMDAGKLVpdALIIGLVKERLKDADC- 77
Cdd:pfam02223   6 GAGKTTQAELLKERLkeqGIKVVFTrepggtpiGEKIRELLLRNEELSPLTEALLFAADRI--QHLEQKIKPALKQGKTv 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 501332908   78 ------ANGYLFDGFPRTIAQADA--MKDAGVAIDYVLEIDVPFSEIVERMSGRRTH 126
Cdd:pfam02223  84 ivdrylFSGIAYQGAKGGDLDLVLslNPDVPGKPDLTFLLDVDPEVALKRLRRRGEL 140
PRK04182 PRK04182
cytidylate kinase; Provisional
 1-36 7.86e-03

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 35.94  E-value: 7.86e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 501332908   1 MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLR 36
Cdd:PRK04182   1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFR 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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