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Conserved domains on  [gi|501386295|ref|WP_012417861|]
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cupin domain-containing protein [Bordetella avium]

Protein Classification

cupin domain-containing protein( domain architecture ID 14401237)

cupin domain-containing protein similar to Pseudomonas aeruginosa BauB which is involved in the degradation of beta-alanine.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
cupin_BauB-like cd06982
Pseudomonas aeruginosa BauB and related proteins, cupin domain; This family includes bacterial ...
 5-94 8.33e-51

Pseudomonas aeruginosa BauB and related proteins, cupin domain; This family includes bacterial proteins homologous to beta-alanine degradation protein BauB from Pseudomonas aeruginosa, which is involved in the degradation of beta-alanine. Also included are Rhodopseudomonas palustris Rpa4178 and Bordetella pertussis Bp2299, which are both proteins with unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.


:

Pssm-ID: 380387 [Multi-domain]  Cd Length: 91  Bit Score: 154.67  E-value: 8.33e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501386295  5 AAIPTVQIDNEHVTVTEWRFPPGAETGWHRHGMHYVVVPQTTGKLLLDTPEGQR-ESQLTTGIAYTRPEGVEHNVINPND 83
Cdd:cd06982   1 QAVPTVQIDNERVRVTRWRFPPGAETGWHRHEYDYVVVPLTDGTLTIEDPDGERtASLLAGGVSYRRPAGVEHNVINAGD 80

                        90
                ....*....|.
gi 501386295 84 TEFVFVEIEIK 94
Cdd:cd06982  81 AEVVFVEIELK 91
 
Name Accession Description Interval E-value
cupin_BauB-like cd06982
Pseudomonas aeruginosa BauB and related proteins, cupin domain; This family includes bacterial ...
 5-94 8.33e-51

Pseudomonas aeruginosa BauB and related proteins, cupin domain; This family includes bacterial proteins homologous to beta-alanine degradation protein BauB from Pseudomonas aeruginosa, which is involved in the degradation of beta-alanine. Also included are Rhodopseudomonas palustris Rpa4178 and Bordetella pertussis Bp2299, which are both proteins with unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.


Pssm-ID: 380387 [Multi-domain]  Cd Length: 91  Bit Score: 154.67  E-value: 8.33e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501386295  5 AAIPTVQIDNEHVTVTEWRFPPGAETGWHRHGMHYVVVPQTTGKLLLDTPEGQR-ESQLTTGIAYTRPEGVEHNVINPND 83
Cdd:cd06982   1 QAVPTVQIDNERVRVTRWRFPPGAETGWHRHEYDYVVVPLTDGTLTIEDPDGERtASLLAGGVSYRRPAGVEHNVINAGD 80

                        90
                ....*....|.
gi 501386295 84 TEFVFVEIEIK 94
Cdd:cd06982  81 AEVVFVEIELK 91
QdoI COG1917
Cupin domain protein related to quercetin dioxygenase [General function prediction only];
9-91 1.59e-08

Cupin domain protein related to quercetin dioxygenase [General function prediction only];


Pssm-ID: 441521 [Multi-domain]  Cd Length: 99  Bit Score: 47.54  E-value: 1.59e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501386295  9 TVQIDNEHVTVTEWRFPPGAETGWHRHGMHYVVVPqTTGKLLLDTpeGQRESQLTTGIAYTRPEGVEHNVINPNDTEFVF 88
Cdd:COG1917  15 VLADGEDELEVVRVTFEPGARTPWHSHPGEELIYV-LEGEGEVEV--GGEEYELKPGDVVFIPPGVPHAFRNLGDEPAVL 91


                ...
gi 501386295 89 VEI 91
Cdd:COG1917  92 LVV 94
Cupin_2 pfam07883
Cupin domain; This family represents the conserved barrel domain of the 'cupin' superfamily ( ...
 21-91 5.96e-04

Cupin domain; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel).


Pssm-ID: 462300 [Multi-domain]  Cd Length: 71  Bit Score: 35.31  E-value: 5.96e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 501386295  21 EWRFPPGAETGWHRHGMH----YVVvpqtTGKLLLDtpEGQRESQLTTGIAYTRPEGVEHNVINPNDTEFVFVEI 91
Cdd:pfam07883  2 LVTLPPGESSPPHRHPGEdeffYVL----EGEGELT--VDGEEVVLKAGDSVYFPAGVPHRFRNTGDEPARLLDV 70
 
Name Accession Description Interval E-value
cupin_BauB-like cd06982
Pseudomonas aeruginosa BauB and related proteins, cupin domain; This family includes bacterial ...
 5-94 8.33e-51

Pseudomonas aeruginosa BauB and related proteins, cupin domain; This family includes bacterial proteins homologous to beta-alanine degradation protein BauB from Pseudomonas aeruginosa, which is involved in the degradation of beta-alanine. Also included are Rhodopseudomonas palustris Rpa4178 and Bordetella pertussis Bp2299, which are both proteins with unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.


Pssm-ID: 380387 [Multi-domain]  Cd Length: 91  Bit Score: 154.67  E-value: 8.33e-51
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501386295  5 AAIPTVQIDNEHVTVTEWRFPPGAETGWHRHGMHYVVVPQTTGKLLLDTPEGQR-ESQLTTGIAYTRPEGVEHNVINPND 83
Cdd:cd06982   1 QAVPTVQIDNERVRVTRWRFPPGAETGWHRHEYDYVVVPLTDGTLTIEDPDGERtASLLAGGVSYRRPAGVEHNVINAGD 80

                        90
                ....*....|.
gi 501386295 84 TEFVFVEIEIK 94
Cdd:cd06982  81 AEVVFVEIELK 91
QdoI COG1917
Cupin domain protein related to quercetin dioxygenase [General function prediction only];
9-91 1.59e-08

Cupin domain protein related to quercetin dioxygenase [General function prediction only];


Pssm-ID: 441521 [Multi-domain]  Cd Length: 99  Bit Score: 47.54  E-value: 1.59e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501386295  9 TVQIDNEHVTVTEWRFPPGAETGWHRHGMHYVVVPqTTGKLLLDTpeGQRESQLTTGIAYTRPEGVEHNVINPNDTEFVF 88
Cdd:COG1917  15 VLADGEDELEVVRVTFEPGARTPWHSHPGEELIYV-LEGEGEVEV--GGEEYELKPGDVVFIPPGVPHAFRNLGDEPAVL 91


                ...
gi 501386295 89 VEI 91
Cdd:COG1917  92 LVV 94
ManC COG0662
Mannose-6-phosphate isomerase, cupin superfamily [Carbohydrate transport and metabolism];
13-92 7.26e-08

Mannose-6-phosphate isomerase, cupin superfamily [Carbohydrate transport and metabolism];


Pssm-ID: 440426 [Multi-domain]  Cd Length: 114  Bit Score: 46.29  E-value: 7.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501386295  13 DNEHVTVTEWRFPPGAETGWHRHGM---HYVVVpqtTGKLLLDTpeGQRESQLTTGIAYTRPEGVEHNVINPNDTEFVFV 89
Cdd:COG0662   23 GGERLSVKRITVPPGAELSLHVHPHrdeFFYVL---EGTGEVTI--GDEEVELKAGDSVYIPAGVPHRLRNPGDEPLELL 97


                 ...
gi 501386295  90 EIE 92
Cdd:COG0662   98 EVQ 100
cupin_RmlC-like cd02208
RmlC-like cupin superfamily; This superfamily contains proteins similar to the RmlC (dTDP ...
 19-91 2.40e-07

RmlC-like cupin superfamily; This superfamily contains proteins similar to the RmlC (dTDP (deoxythymidine diphosphates)-4-dehydrorhamnose 3,5-epimerase)-like cupins. RmlC is a dTDP-sugar isomerase involved in the synthesis of L-rhamnose, a saccharide required for the virulence of some pathogenic bacteria. Cupins are a functionally diverse superfamily originally discovered based on the highly conserved motif found in germin and germin-like proteins. This conserved motif forms a beta-barrel fold found in all of the cupins, giving rise to the name cupin ('cupa' is the Latin term for small barrel). The active site of members of this superfamily is generally located at the center of a conserved barrel and usually includes a metal ion. The different functional classes in this superfamily include single domain bacterial isomerases and epimerases involved in the modification of cell wall carbohydrates, two domain bicupins such as the desiccation-tolerant seed storage globulins, and multidomain nuclear transcription factors involved in legume root nodulation.


Pssm-ID: 380338 [Multi-domain]  Cd Length: 73  Bit Score: 44.01  E-value: 2.40e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 501386295 19 VTEWRFPPGAETGWHRHGMHY--VVVPQTTGKLLLDtpeGQRESQLTTGIAYTRPEGVEHNVINPNDTEFVFVEI 91
Cdd:cd02208   1 ISVVTLPPGTSSPPHWHPEQDeiFYVLSGEGELTLD---DGETVELKAGDIVLIPPGVPHSFVNTSDEPAVFLVV 72
cupin_CV2614-like cd02236
Chromobacterium violaceum CV2614 and related proteins, cupin domain; This family includes ...
 17-84 2.25e-05

Chromobacterium violaceum CV2614 and related proteins, cupin domain; This family includes mostly bacterial proteins homologous to CV2614, a Chromobacterium violaceum protein of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.


Pssm-ID: 380364 [Multi-domain]  Cd Length: 102  Bit Score: 39.40  E-value: 2.25e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 501386295  17 VTVTEWRFPPGAETGWHRHGMH-YVVVpqTTGKLLLDTPEGQReSQLTTGIAYtrPEGVE--HNVINPNDT 84
Cdd:cd02236   22 ITVLRITIPPGAELPWHTHPVPnAGYV--LSGELTVEYEDGKK-RTFKAGDAF--VEAVNtwHRGRNGGDE 87
Cupin_2 pfam07883
Cupin domain; This family represents the conserved barrel domain of the 'cupin' superfamily ( ...
 21-91 5.96e-04

Cupin domain; This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel).


Pssm-ID: 462300 [Multi-domain]  Cd Length: 71  Bit Score: 35.31  E-value: 5.96e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 501386295  21 EWRFPPGAETGWHRHGMH----YVVvpqtTGKLLLDtpEGQRESQLTTGIAYTRPEGVEHNVINPNDTEFVFVEI 91
Cdd:pfam07883  2 LVTLPPGESSPPHRHPGEdeffYVL----EGEGELT--VDGEEVVLKAGDSVYFPAGVPHRFRNTGDEPARLLDV 70
OxdD COG2140
Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily [Carbohydrate ...
 23-91 9.26e-03

Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily [Carbohydrate transport and metabolism]; Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 441743 [Multi-domain]  Cd Length: 115  Bit Score: 33.02  E-value: 9.26e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 501386295  23 RFPPGAETG--WHRHGMHYVVVPQTTGKLLLDTPEGQ-RESQLTTG-IAYTrPEGVEHNVINPNDTEFVFVEI 91
Cdd:COG2140    9 VLEPGGVREehWHPNAAEWYYVLSGEARMTVQDPPGRaRTVDVGPGdVVYV-PPGYGHYIINTGDEPLVFLAV 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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