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Conserved domains on  [gi|501501989|ref|WP_012510207|]
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MULTISPECIES: GNAT family N-acetyltransferase [Stenotrophomonas]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10003213)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 47-147 1.13e-13

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


:

Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 63.47  E-value: 1.13e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989  47 FQVIERDGSIVACGGLSRRGDGSAGFCWGMVQRALHRHGLGRELALARLRQAEADpSINRITLSTSQHTQGFYAGLGFRV 126
Cdd:COG1246   30 FWVAEEDGEIVGCAALHPLDEDLAELRSLAVHPDYRGRGIGRRLLEALLAEAREL-GLKRLFLLTTSAAIHFYEKLGFEE 108

                         90       100
                 ....*....|....*....|...
gi 501501989 127 T--RVVPDGHGAGIDAVEMEREL 147
Cdd:COG1246  109 IdkEDLPYAKVWQRDSVVMEKDL 131
 
Name Accession Description Interval E-value
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 47-147 1.13e-13

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 63.47  E-value: 1.13e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989  47 FQVIERDGSIVACGGLSRRGDGSAGFCWGMVQRALHRHGLGRELALARLRQAEADpSINRITLSTSQHTQGFYAGLGFRV 126
Cdd:COG1246   30 FWVAEEDGEIVGCAALHPLDEDLAELRSLAVHPDYRGRGIGRRLLEALLAEAREL-GLKRLFLLTTSAAIHFYEKLGFEE 108

                         90       100
                 ....*....|....*....|...
gi 501501989 127 T--RVVPDGHGAGIDAVEMEREL 147
Cdd:COG1246  109 IdkEDLPYAKVWQRDSVVMEKDL 131
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 49-126 4.58e-10

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 52.84  E-value: 4.58e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 501501989   49 VIERDGSIVACGGLSRRGDGSAGFCWGM-VQRALHRHGLGRELaLARLRQAEADPSINRITLSTSQHTQGFYAGLGFRV 126
Cdd:pfam13508   7 VAEDDGKIVGFAALLPLDDEGALAELRLaVHPEYRGQGIGRAL-LEAAEAAAKEGGIKLLELETTNRAAAFYEKLGFEE 84
 
Name Accession Description Interval E-value
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 47-147 1.13e-13

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 63.47  E-value: 1.13e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989  47 FQVIERDGSIVACGGLSRRGDGSAGFCWGMVQRALHRHGLGRELALARLRQAEADpSINRITLSTSQHTQGFYAGLGFRV 126
Cdd:COG1246   30 FWVAEEDGEIVGCAALHPLDEDLAELRSLAVHPDYRGRGIGRRLLEALLAEAREL-GLKRLFLLTTSAAIHFYEKLGFEE 108

                         90       100
                 ....*....|....*....|...
gi 501501989 127 T--RVVPDGHGAGIDAVEMEREL 147
Cdd:COG1246  109 IdkEDLPYAKVWQRDSVVMEKDL 131
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
26-147 4.37e-10

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 54.32  E-value: 4.37e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989  26 FAPEERSDFERFLREQAMGCAFQVIERDGSIVACGGLSR---RGDGSAGFCWGM-VQRALHRHGLGREL---ALARLRQA 98
Cdd:COG3153   20 FGPGREAELVDRLREDPAAGLSLVAEDDGEIVGHVALSPvdiDGEGPALLLGPLaVDPEYRGQGIGRALmraALEAARER 99

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 501501989  99 EADpsinRITLSTSQHTQGFYAGLGFRVTRvvPDGHGAGIDAVEMEREL 147
Cdd:COG3153  100 GAR----AVVLLGDPSLLPFYERFGFRPAG--ELGLTLGPDEVFLAKEL 142
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 49-126 4.58e-10

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 52.84  E-value: 4.58e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 501501989   49 VIERDGSIVACGGLSRRGDGSAGFCWGM-VQRALHRHGLGRELaLARLRQAEADPSINRITLSTSQHTQGFYAGLGFRV 126
Cdd:pfam13508   7 VAEDDGKIVGFAALLPLDDEGALAELRLaVHPEYRGQGIGRAL-LEAAEAAAKEGGIKLLELETTNRAAAFYEKLGFEE 84
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-147 2.00e-09

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 53.07  E-value: 2.00e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989   1 MTPRPYCCSDMTACLSIFDSNVP----TYF-APEERSDFERFLRE-QAMGCAFQVIERDGSIV--ACGGLSRRGDGSAGF 72
Cdd:COG1247    2 MTIRPATPEDAPAIAAIYNEAIAegtaTFEtEPPSEEEREAWFAAiLAPGRPVLVAEEDGEVVgfASLGPFRPRPAYRGT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989  73 CWG--MVQRALHRHGLGREL---ALARLRQAEadpsINRI---TLSTSQHTQGFYAGLGFRVTRVVPDG---HGAGIDAV 141
Cdd:COG1247   82 AEEsiYVDPDARGRGIGRALleaLIERARARG----YRRLvavVLADNEASIALYEKLGFEEVGTLPEVgfkFGRWLDLV 157


                 ....*.
gi 501501989 142 EMEREL 147
Cdd:COG1247  158 LMQKRL 163
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 26-147 1.01e-08

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 50.35  E-value: 1.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989   26 FAPEERSDFERFLREQAM-------GCAFQVIERDGSIVACGGLsRRGDGSAGFCwgmVQRALHRHGLGRELALARLRQA 98
Cdd:pfam13673   5 YSEEGIETFYEFISPEALreridqgEYFFFVAFEGGQIVGVIAL-RDRGHISLLF---VDPDYQGQGIGKALLEAVEDYA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 501501989   99 EAD-PSINRITLSTSQHTQGFYAGLGFRVTrvVPDGHGAGIDAVEMEREL 147
Cdd:pfam13673  81 EKDgIKLSELTVNASPYAVPFYEKLGFRAT--GPEQEFNGIRFVPMEKEL 128
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
49-147 1.64e-08

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 49.80  E-value: 1.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989  49 VIERDGSIVACGGLSRRGDGSAGFCWGMVQRALHRHGLGRELALARLRQAEADPsINRITLSTSQHTQGFYAGLGFRVT- 127
Cdd:COG2153   38 LAYDDGELVATARLLPPGDGEAKIGRVAVLPEYRGQGLGRALMEAAIEEARERG-ARRIVLSAQAHAVGFYEKLGFVPVg 116

                         90       100
                 ....*....|....*....|
gi 501501989 128 RVVPDghgAGIDAVEMEREL 147
Cdd:COG2153  117 EEFLE---AGIPHIDMRKPL 133
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 16-124 3.04e-06

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 43.66  E-value: 3.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989   16 SIFDSNVPTYFAPEERSDFERFL-REQAMGCAFQVIERDGSIVACGGLSRRGDGSA-GFCWGM-VQRALHRHGLGRELAL 92
Cdd:pfam00583   3 ALYELLSEEFPEPWPDEPLDLLEdWDEDASEGFFVAEEDGELVGFASLSIIDDEPPvGEIEGLaVAPEYRGKGIGTALLQ 82

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 501501989   93 ARLRQAEADpSINRITLSTS---QHTQGFYAGLGF 124
Cdd:pfam00583  83 ALLEWARER-GCERIFLEVAadnLAAIALYEKLGF 116
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 77-147 2.34e-05

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 40.79  E-value: 2.34e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 501501989  77 VQRALHRHGLGRELaLARLRQAEADPSINRITLSTSQH---TQGFYAGLGFRVTRVVPDGHGAgiDAVEMEREL 147
Cdd:COG0456   21 VDPEYRGRGIGRAL-LEAALERARERGARRLRLEVREDneaAIALYEKLGFEEVGERPNYYGD--DALVMEKEL 91
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 23-145 2.79e-05

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 41.91  E-value: 2.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989  23 PTYFAPEERSDFERFLRE-----QAMGCAFQVIER--DGSIVACGGLSR--RGDGSAGFCWgMVQRALHRHGLGRELALA 93
Cdd:COG1670   33 YLPGPPYSLEEARAWLERlladwADGGALPFAIEDkeDGELIGVVGLYDidRANRSAEIGY-WLAPAYWGKGYATEALRA 111

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 501501989  94 RLRQAEADPSINRITLSTSQH---TQGFYAGLGFRVTRVVPDG---HGAGIDAVEMER 145
Cdd:COG1670  112 LLDYAFEELGLHRVEAEVDPDntaSIRVLEKLGFRLEGTLRDAlviDGRYRDHVLYSL 169
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 30-147 4.82e-05

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 40.81  E-value: 4.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989  30 ERSDFERFLREQAM------------GCAFQVIERDGSIVACGGLSRRGDGSaGFCWGM-VQRALHRHGLGRELaLARLR 96
Cdd:COG0454    7 TPEDINFILLIEALdaelkamegslaGAEFIAVDDKGEPIGFAGLRRLDDKV-LELKRLyVLPEYRGKGIGKAL-LEALL 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 501501989  97 QAEADPSINRITLSTS---QHTQGFYAGLGFRVTRVVPDGHGagidaVEMEREL 147
Cdd:COG0454   85 EWARERGCTALELDTLdgnPAAIRFYERLGFKEIERYVAYVG-----GEFEKEL 133
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 4-125 1.42e-03

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 36.56  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 501501989    4 RPYCCSDMTACLSIF-DSNVPTYFAPEERSD------FERFLREQA--MGCAFQVIERDGSIVACGGLSRRGDGSAGFCW 74
Cdd:pfam13302   5 RPLTEEDAEALFELLsDPEVMRYGVPWPLTLeearewLARIWAADEaeRGYGWAIELKDTGFIGSIGLYDIDGEPERAEL 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 501501989   75 G-MVQRALHRHGLGRELALARLRQAEADPSINRITLSTSQH---TQGFYAGLGFR 125
Cdd:pfam13302  85 GyWLGPDYWGKGYATEAVRALLEYAFEELGLPRLVARIDPEntaSRRVLEKLGFK 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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