|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-428 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 927.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 1 MSMITEIYAREILDSRGNPSVEVEVFTEDGGFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELI 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 81 GYDVFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLPTPMMNIINGGSHADNNV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 161 DFQEFMIMPVGAPTFREALRMGAEVFHALKSVLSGMGLNTAVGDEGGFAPNLKSNEEAITVILEAIEKAGYKPGEDVYLA 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 241 MDVASSEFYDKstGKYELAGEGKSLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLLTDKIGHKVQLVGDDLFVTN 320
Cdd:COG0148 241 LDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 321 TSKLAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSLSRTDRI 400
Cdd:COG0148 319 PKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERV 398
|
410 420
....*....|....*....|....*...
gi 502178791 401 AKYNQLLRIEDMLGDVAKYDGIKSFYNL 428
Cdd:COG0148 399 AKYNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-429 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 891.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 1 MSMITEIYAREILDSRGNPSVEVEVFTEDGGFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELI 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 81 GYDVFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLPTPMMNIINGGSHADNNV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 161 DFQEFMIMPVGAPTFREALRMGAEVFHALKSVLSGMGLNTAVGDEGGFAPNLKSNEEAITVILEAIEKAGYKPGEDVYLA 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 241 MDVASSEFYDksTGKYELAGEGksLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLLTDKIGHKVQLVGDDLFVTN 320
Cdd:PRK00077 241 LDCAASEFYK--DGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 321 TSKLAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSLSRTDRI 400
Cdd:PRK00077 317 TKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERI 396
|
410 420
....*....|....*....|....*....
gi 502178791 401 AKYNQLLRIEDMLGDVAKYDGIKSFYNLK 429
Cdd:PRK00077 397 AKYNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-428 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 782.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 4 ITEIYAREILDSRGNPSVEVEVFTEDGGFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELIGYD 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 84 VFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLPTPMMNIINGGSHADNNVDFQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 164 EFMIMPVGAPTFREALRMGAEVFHALKSVLSGMGLNTAVGDEGGFAPNLKSNEEAITVILEAIEKAGYKPGEDVYLAMDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 244 ASSEFYDKSTGKYELAGEGKSLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLLTDKIGHKVQLVGDDLFVTNTSK 323
Cdd:TIGR01060 241 AASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 324 LAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSLSRTDRIAKY 403
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400
|
410 420
....*....|....*....|....*
gi 502178791 404 NQLLRIEDMLGDVAKYDGIKSFYNL 428
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
6-411 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 761.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 6 EIYAREILDSRGNPSVEVEVFTEDGGFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELIGYDVF 85
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 86 DQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLPTPMMNIINGGSHADNNVDFQEF 165
Cdd:cd03313 81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 166 MIMPVGAPTFREALRMGAEVFHALKSVLSGMG--LNTAVGDEGGFAPNLKSNEEAITVILEAIEKAGYKPGEDVYLAMDV 243
Cdd:cd03313 161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 244 ASSEFYDKSTGKYElAGEGKSLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLLTDKIGHKVQLVGDDLFVTNTSK 323
Cdd:cd03313 241 AASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPER 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 324 LAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSLSRTDRIAKY 403
Cdd:cd03313 320 LKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKY 399
|
....*...
gi 502178791 404 NQLLRIED 411
Cdd:cd03313 400 NQLLRIEE 407
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
139-428 |
2.72e-168 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 473.89 E-value: 2.72e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 139 AKTLPTPMMNIINGGSHADNNVDFQEFMIMPVGAPTFREALRMGAEVFHALKSVLS--GMGLNTAVGDEGGFAPNLKSNE 216
Cdd:pfam00113 1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKakYGQSATNVGDEGGFAPNLQSNK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 217 EAITVILEAIEKAGYKPgeDVYLAMDVASSEFYDKSTGKYELAGEG------KSLTTAELVDFYAELVDKYPILSIEDGC 290
Cdd:pfam00113 81 EALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 291 DENDWDGHKLLTDKIGHKVQLVGDDLFVTNTSKLAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSG 370
Cdd:pfam00113 159 DEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSG 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 502178791 371 ETEDATIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDMLGDVAKYDGIKSFYNL 428
Cdd:pfam00113 239 ETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-428 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 927.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 1 MSMITEIYAREILDSRGNPSVEVEVFTEDGGFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELI 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 81 GYDVFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLPTPMMNIINGGSHADNNV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 161 DFQEFMIMPVGAPTFREALRMGAEVFHALKSVLSGMGLNTAVGDEGGFAPNLKSNEEAITVILEAIEKAGYKPGEDVYLA 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 241 MDVASSEFYDKstGKYELAGEGKSLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLLTDKIGHKVQLVGDDLFVTN 320
Cdd:COG0148 241 LDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTN 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 321 TSKLAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSLSRTDRI 400
Cdd:COG0148 319 PKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERV 398
|
410 420
....*....|....*....|....*...
gi 502178791 401 AKYNQLLRIEDMLGDVAKYDGIKSFYNL 428
Cdd:COG0148 399 AKYNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-429 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 891.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 1 MSMITEIYAREILDSRGNPSVEVEVFTEDGGFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELI 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 81 GYDVFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLPTPMMNIINGGSHADNNV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 161 DFQEFMIMPVGAPTFREALRMGAEVFHALKSVLSGMGLNTAVGDEGGFAPNLKSNEEAITVILEAIEKAGYKPGEDVYLA 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 241 MDVASSEFYDksTGKYELAGEGksLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLLTDKIGHKVQLVGDDLFVTN 320
Cdd:PRK00077 241 LDCAASEFYK--DGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 321 TSKLAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSLSRTDRI 400
Cdd:PRK00077 317 TKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERI 396
|
410 420
....*....|....*....|....*....
gi 502178791 401 AKYNQLLRIEDMLGDVAKYDGIKSFYNLK 429
Cdd:PRK00077 397 AKYNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-428 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 782.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 4 ITEIYAREILDSRGNPSVEVEVFTEDGGFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELIGYD 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 84 VFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLPTPMMNIINGGSHADNNVDFQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 164 EFMIMPVGAPTFREALRMGAEVFHALKSVLSGMGLNTAVGDEGGFAPNLKSNEEAITVILEAIEKAGYKPGEDVYLAMDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 244 ASSEFYDKSTGKYELAGEGKSLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLLTDKIGHKVQLVGDDLFVTNTSK 323
Cdd:TIGR01060 241 AASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 324 LAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSLSRTDRIAKY 403
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400
|
410 420
....*....|....*....|....*
gi 502178791 404 NQLLRIEDMLGDVAKYDGIKSFYNL 428
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
6-411 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 761.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 6 EIYAREILDSRGNPSVEVEVFTEDGGFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELIGYDVF 85
Cdd:cd03313 1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 86 DQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLPTPMMNIINGGSHADNNVDFQEF 165
Cdd:cd03313 81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 166 MIMPVGAPTFREALRMGAEVFHALKSVLSGMG--LNTAVGDEGGFAPNLKSNEEAITVILEAIEKAGYKPGEDVYLAMDV 243
Cdd:cd03313 161 MIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 244 ASSEFYDKSTGKYElAGEGKSLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLLTDKIGHKVQLVGDDLFVTNTSK 323
Cdd:cd03313 241 AASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPER 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 324 LAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSLSRTDRIAKY 403
Cdd:cd03313 320 LKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKY 399
|
....*...
gi 502178791 404 NQLLRIED 411
Cdd:cd03313 400 NQLLRIEE 407
|
|
| PTZ00081 |
PTZ00081 |
enolase; Provisional |
1-421 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 240259 [Multi-domain] Cd Length: 439 Bit Score: 592.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 1 MSMITEIYAREILDSRGNPSVEVEVFTEDGGFgRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELI 80
Cdd:PTZ00081 1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 81 GYDVFDQNAIDAKMIE-LDGTPN-----KAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKT-----LPTPMMNI 149
Cdd:PTZ00081 80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKPtdkfvLPVPCFNV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 150 INGGSHADNNVDFQEFMIMPVGAPTFREALRMGAEVFHALKSVLSG-MGLN-TAVGDEGGFAPNLKSNEEAITVILEAIE 227
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKkYGLDaTNVGDEGGFAPNIKDPEEALDLLVEAIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 228 KAGYKpGEdVYLAMDVASSEFYDKSTGKYEL------AGEGKSLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLL 301
Cdd:PTZ00081 240 KAGYE-GK-VKICMDVAASEFYDKEKKVYDLdfknpnNDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 302 TDKIGHKVQLVGDDLFVTNTSKLAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIA 381
Cdd:PTZ00081 318 TAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLV 397
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 502178791 382 VATNAGQIKTGSLSRTDRIAKYNQLLRIEDMLGDVAKYDG 421
Cdd:PTZ00081 398 VGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAG 437
|
|
| PLN00191 |
PLN00191 |
enolase |
1-421 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 543.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 1 MSMITEIYAREILDSRGNPSVEVEVFTEDGGFgRALVPSGASTGEHEAVELRDGDKsRYLGKGVLKAVANVNDTIAPELI 80
Cdd:PLN00191 25 MATITKVKARQIIDSRGNPTVEVDLHTSKGMF-RAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 81 GYDVFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTY---LGGFNAKTLPTPMMNIINGGSHAD 157
Cdd:PLN00191 103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHiadLAGNKKLVLPVPAFNVINGGSHAG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 158 NNVDFQEFMIMPVGAPTFREALRMGAEVFHALKSVLSGM--GLNTAVGDEGGFAPNLKSNEEAITVILEAIEKAGYKpgE 235
Cdd:PLN00191 183 NKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT--G 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 236 DVYLAMDVASSEFYDKStGKYEL------AGEGKSLTTAELVDFYAELVDKYPILSIEDGCDENDWDGHKLLTDKIghKV 309
Cdd:PLN00191 261 KIKIGMDVAASEFYTKD-KKYDLdfkeenNDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSLE--DV 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 310 QLVGDDLFVTNTSKLAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQI 389
Cdd:PLN00191 338 QIVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQI 417
|
410 420 430
....*....|....*....|....*....|..
gi 502178791 390 KTGSLSRTDRIAKYNQLLRIEDMLGDVAKYDG 421
Cdd:PLN00191 418 KTGAPCRSERLAKYNQLLRIEEELGDEAVYAG 449
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
139-428 |
2.72e-168 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 473.89 E-value: 2.72e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 139 AKTLPTPMMNIINGGSHADNNVDFQEFMIMPVGAPTFREALRMGAEVFHALKSVLS--GMGLNTAVGDEGGFAPNLKSNE 216
Cdd:pfam00113 1 SYVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKakYGQSATNVGDEGGFAPNLQSNK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 217 EAITVILEAIEKAGYKPgeDVYLAMDVASSEFYDKSTGKYELAGEG------KSLTTAELVDFYAELVDKYPILSIEDGC 290
Cdd:pfam00113 81 EALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 291 DENDWDGHKLLTDKIGHKVQLVGDDLFVTNTSKLAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSG 370
Cdd:pfam00113 159 DEDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSG 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 502178791 371 ETEDATIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDMLGDVAKYDGIKSFYNL 428
Cdd:pfam00113 239 ETEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| Enolase_N |
pfam03952 |
Enolase, N-terminal domain; |
4-134 |
2.32e-83 |
|
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain] Cd Length: 131 Bit Score: 251.53 E-value: 2.32e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 4 ITEIYAREILDSRGNPSVEVEVFTEDGGFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVANVNDTIAPELIGYD 83
Cdd:pfam03952 1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 502178791 84 VFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYL 134
Cdd:pfam03952 81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
|
|
| PRK08350 |
PRK08350 |
hypothetical protein; Provisional |
1-415 |
5.22e-23 |
|
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain] Cd Length: 341 Bit Score: 99.11 E-value: 5.22e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 1 MSMITEIYAREILDSRGNPSVEVEVFTeDGGFGRALVPSgastgeheavelrDGDKSRYLGKGvLKAVANVNDTIAPELI 80
Cdd:PRK08350 1 MTVIENIIGRVAVLRGGKYSVEVDVIT-DSGFGRFAAPI-------------DENPSLYIAEA-HRAVSEVDEIIGPELI 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 81 GYDVFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLPTPMMNIINGGshadnnv 160
Cdd:PRK08350 66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTTELPVPILEFAEDE------- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 161 DFQEFMIMpvgaptfREALRMgAEVFHALKSVLSgmglntavgdeggfapnlKSNEEAITVILEAIEKAGYKPGEDVYLA 240
Cdd:PRK08350 139 NFEYYVLV-------RDLMEI-TDVVDAVNKILE------------------NSKEVSLEGLSKASEKAGDELGLEVALG 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 241 MdvassefydkstgkyelaGEGKSLTTAELVdfyaELVDKYPILSIEDGCDEndwdghKLLTDKIG--HKVQLVGDDLFV 318
Cdd:PRK08350 193 I------------------AQKREMETEKVL----NLVEDNNIAYIKPIGDE------ELFLELIAgtHGVFIDGEYLFR 244
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 319 TNTSklaegIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSGETEDATIADIAVATNAGQIktgsLSRTD 398
Cdd:PRK08350 245 TRNI-----LDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRCPAM----LIHKD 315
|
410
....*....|....*..
gi 502178791 399 RIAKYNQLLRIEDMLGD 415
Cdd:PRK08350 316 SVEKINELNRIAEDLGE 332
|
|
| enolase_like |
cd00308 |
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ... |
214-391 |
1.37e-15 |
|
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain] Cd Length: 229 Bit Score: 75.44 E-value: 1.37e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 214 SNEEAITVILEAIekagykpGEDVYLAMDVASSefydkstgkyelagegksLTTAELVDFYAELvDKYPILSIEDGCDEN 293
Cdd:cd00308 79 GSIERVRAVREAF-------GPDARLAVDANGA------------------WTPKEAIRLIRAL-EKYGLAWIEEPCAPD 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 294 DWDGHKLLTDKIGhkVQLVGDDLFVTNTSKLaEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVVSHRSG-ET 372
Cdd:cd00308 133 DLEGYAALRRRTG--IPIAADESVTTVDDAL-EALELGAVDILQIKPTRVGGLTESRRAADLAEAFGIRVMVHGTLEsSI 209
|
170 180
....*....|....*....|
gi 502178791 373 EDATIADIAVAT-NAGQIKT 391
Cdd:cd00308 210 GTAAALHLAAALpNDRAIET 229
|
|
| RspA |
COG4948 |
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ... |
21-386 |
7.88e-08 |
|
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 443975 [Multi-domain] Cd Length: 359 Bit Score: 54.06 E-value: 7.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 21 VEVEVFTEDGGFGRALVPSGASTGEHEA--VELRDGD------KSRYLGKGVLKAVANVNDTIAPELIGYDVFDQNAIDA 92
Cdd:COG4948 4 TDIEVYPVRLPLKRPFTISRGTRTERDVvlVRVETDDgitgwgEAVPGGTGAEAVAAALEEALAPLLIGRDPLDIEALWQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 93 KMIELDGTPNKAKlGA--NAILgvsmaaahaaaD----ELGLPLYTYLGGFNAKTLPTpmmniinGGSHADNNVDfqEFM 166
Cdd:COG4948 84 RLYRALPGNPAAK-AAvdMALW-----------DllgkALGVPVYQLLGGKVRDRVPV-------YATLGIDTPE--EMA 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 167 impvgaptfREALRMGAEVFHALKSVLSGMGLNTAVgdeggfapnlksneEAITVILEAIekagykpGEDVYLAMDvass 246
Cdd:COG4948 143 ---------EEAREAVARGFRALKLKVGGPDPEEDV--------------ERVRAVREAV-------GPDARLRVD---- 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 247 efydkstgkyelAGEGksLTTAELVDFYAELvDKYPILSIEDGCDENDWDGHKLLTDKIGhkVQLVGDDLfVTNTSKLAE 326
Cdd:COG4948 189 ------------ANGA--WTLEEAIRLLRAL-EDLGLEWIEQPLPAEDLEGLAELRRATP--VPIAADES-LTSRADFRR 250
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 327 GIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGyTAVVSHRSGETedatiaDIAVATNA 386
Cdd:COG4948 251 LIEAGAVDIVNIKLSKVGGLTEALRIAALAEAHG-VPVMPHCMLES------GIGLAAAL 303
|
|
| PTZ00378 |
PTZ00378 |
hypothetical protein; Provisional |
77-413 |
1.25e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 173571 [Multi-domain] Cd Length: 518 Bit Score: 44.10 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 77 PELIGYDVFDQNAIDAKMIELDGTPNKAKLGANAILGVSMAAAHAAADELGLPLYTYLGGF-----NAKTLPTPMMNII- 150
Cdd:PTZ00378 117 PRLLQLGARDQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPLFQYLRALfgsltSVETFSMPQLCITf 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 151 ----NGGSHADNNVDFQEFMIMPVGAPTFREALRMGAEVFHALKSvlsgmgLNTAVGDEGGFAPNLKSN-EEAITVILEA 225
Cdd:PTZ00378 197 fgpgNPSTARLALKSVLFSPVMPSGTVLRERMQKIFAAFHHFCQS------HNSSVRSDGSLHWDGFANlTDAVKLATEA 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 226 IEKAGYKPGEDVYLAMDVASS----------------EFYDKSTGKYELAGEGKSLTTAELVDFYAELVDKYP--ILSIE 287
Cdd:PTZ00378 271 LRAVQLTPGTDVCLGLRMAASttrvpatavadggawkEAKDDCEVLYSLFPGEPDVTGDQLSEYVREQLQAVPdiVVYVE 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 288 DG-CDEnDWDGHKLLTDKIGHKVQLVGDDLFVTNTSKLAE-GIEKGIANSILIKVNQIGTLTETFDAIEMAKK-AGYTAV 364
Cdd:PTZ00378 351 DThCDE-DTFGLQRLQAALGDSIVLSGVDVYARSEYKKVEsGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGEdEGRAVT 429
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 502178791 365 VSHRSGETEDATIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDML 413
Cdd:PTZ00378 430 VLVQTLAGNAATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDEL 478
|
|
| MLE |
cd03318 |
Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis, ... |
19-143 |
1.86e-04 |
|
Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis,cis-muconate (CCM) to muconolactone (ML) in the catechol branch of the beta-ketoadipate pathway. This pathway is used in soil microbes to breakdown lignin-derived aromatics, catechol and protocatechuate, to citric acid cycle intermediates. Some bacterial species are also capable of dehalogenating chloroaromatic compounds by the action of chloromuconate lactonizing enzymes (Cl-MLEs). MLEs are members of the enolase superfamily characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and that is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239434 [Multi-domain] Cd Length: 365 Bit Score: 43.46 E-value: 1.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 19 PSVEVEVFTEDG--GFGRALVPSGASTGEhEAVElrdgdksrylgkgvlKAVANVNDTIAPELIGYDVFDQNAIDAKMie 96
Cdd:cd03318 29 SLVLVRLTTSDGvvGIGEATTPGGPAWGG-ESPE---------------TIKAIIDRYLAPLLIGRDATNIGAAMALL-- 90
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 502178791 97 ldgtpNKAKLG-ANAILGVSMAAAHAAADELGLPLYTYLGGFNAKTLP 143
Cdd:cd03318 91 -----DRAVAGnLFAKAAIEMALLDAQGRRLGLPVSELLGGRVRDSLP 133
|
|
| NAAAR |
cd03317 |
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of ... |
216-399 |
5.00e-03 |
|
N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239433 [Multi-domain] Cd Length: 354 Bit Score: 38.75 E-value: 5.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 216 EEAITVILEAIEKA---GY-------KPGEDVYLAMDVAssefydKSTGKYELAGEGKSLTTAELVDFYAELvDKYPILS 285
Cdd:cd03317 135 QDDVEQLLKQIERYleeGYkriklkiKPGWDVEPLKAVR------ERFPDIPLMADANSAYTLADIPLLKRL-DEYGLLM 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 286 IEDGCDENDWDGHKLLTDKIGHKVQLvgdDLFVTNTSKLAEGIEKGIANSILIKVNQIGTLTETFDAIEMAKKAGYTAVV 365
Cdd:cd03317 208 IEQPLAADDLIDHAELQKLLKTPICL---DESIQSAEDARKAIELGACKIINIKPGRVGGLTEALKIHDLCQEHGIPVWC 284
|
170 180 190
....*....|....*....|....*....|....*..
gi 502178791 366 shrsG---ETEDATIADIAVATNAGQIKTGSLSRTDR 399
Cdd:cd03317 285 ----GgmlESGIGRAHNVALASLPNFTYPGDISASSR 317
|
|
| MR_like_4 |
cd03329 |
Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 4. Enzymes of this ... |
20-205 |
9.16e-03 |
|
Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 4. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues, a Lys-X-Lys motif and a conserved histidine-aspartate dyad. This subgroup's function is unknown.
Pssm-ID: 239445 [Multi-domain] Cd Length: 368 Bit Score: 38.15 E-value: 9.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 20 SVEVEVFTED----GGFGRALVPSGASTGEHEAVEL--RDGDKSRYLGKGVLKAVANVNDTIAPELIGYDVFDQNAIDAK 93
Cdd:cd03329 4 DVEVTVFEYPtqpvSFDGGHHHPGPAGTRKLALLTIetDEGAKGHAFGGRPVTDPALVDRFLKKVLIGQDPLDRERLWQD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502178791 94 MIELDGTPNKAKLGAnailgVSMAAAHAAADELGLPLYTYLGGFNAKtLP----TPMMNIINGGSHADNNVDFQE----- 164
Cdd:cd03329 84 LWRLQRGLTDRGLGL-----VDIALWDLAGKYLGLPVHRLLGGYREK-IPayasTMVGDDLEGLESPEAYADFAEeckal 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 502178791 165 ----FMIMPVGAPTfreaLRMGAEVFHALKSvlsgmglntAVGDE 205
Cdd:cd03329 158 gyraIKLHPWGPGV----VRRDLKACLAVRE---------AVGPD 189
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|
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