|
Name |
Accession |
Description |
Interval |
E-value |
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
9-708 |
1.38e-143 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 436.89 E-value: 1.38e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 9 VVHNPWKIIVGWIIAAVALVAFGPQLSSVTNDNqSSFLPSkYESVQAKNALDAEFPSTVGQVATIVIRPVGDGALSAAEQ 88
Cdd:COG2409 1 VARHRWLVLLAWLVLLVALGVLAPQLGGSLSSN-GFFLPG-SESQRAADLLAEAFPESDGASAVVVVEAPDGTLTDPAFR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 89 QKVSDLATTLTGDhiTGVAGVQ-------AGQVSPKQTAQLMFAKLTADQGDQkaSSDAVKALRaDLAAKLNGSGMKAEV 161
Cdd:COG2409 79 AAVAALVARLRAD--PGVAGVQdpwddpaAGLVSEDGKAALVTVTLDGDAGDE--AAEAVDALR-DAVAAAPAPGLTVYV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 162 TGDAAMGLDTSDSSNKATGIVMMATLLLIIVLMGFIFRGVIAVLLPILSVFLVMMVSQPVIALMAKGFGlhVQSFLEIML 241
Cdd:COG2409 154 TGPAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAAFTD--VSSFAPNLL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 242 VVVLFGIGTDYIVFLLFRLRERLRAGDTIQQAVATTVERVGEAIASAAAAVIIAFCALGLATFKAFTSLGPALAIAVAVM 321
Cdd:COG2409 232 TMLGLGVGIDYALFLVSRYREELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 322 LLAGLTLVPALMVTLGTKIFWPGKKWRRV---PTAGPARKVGNLVGKRPAAVAAVSFVIMAGLAVGAVGFKADYDQQSQM 398
Cdd:COG2409 312 VLAALTLLPALLALLGRRVFWPRRPRRRRaaaPESGFWRRLARAVVRRPVPVLVAAVAVLLALALPALGLRLGLPDADSL 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 399 PGGVESTIAIKDMQkAGFAQGATAATDVIVTST-DGKPLDQAKLQTYADGLGAaspeLSGLmpfpvkpgspAGTKGATVE 477
Cdd:COG2409 392 PADSPSRQGYDALA-EHFPPGSNGPLTVVVESDdDLDPADLAALDALAAALAA----VPGV----------ASVQPPTRP 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 478 YNQAGTAAHIQVLTKDSPFAAAAMSAVDgPLKSAAHSTVPaGAKALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVL 557
Cdd:COG2409 457 EGTDGDAARLQVVPDGDPDSPEAIDLVD-RLRDAAAPALE-GAEVLVGGTTAVNIDISDALADDLPLVIPVVLGLIFLLL 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 558 ALQLRALVAPLYLMVAVGLGYTGTLGASVLMFQTVQ-----NKPGMMFMLPVMVYLFVVAIGTDYNILMISRLREEAREG 632
Cdd:COG2409 535 LLLFRSVVAPLKAVLTNLLSLGAALGVLVLVFQHGWlllgfTPGPLDSFVPLLLFVILFGLGMDYEVFLVSRIREEYDRG 614
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502434125 633 HDPRRAAALAVEHAGPSVASAGLILAGTFASLMLGGLAMMQQIGFAVSFGISIAAFVMSMFLVPAVTALMGAKAWW 708
Cdd:COG2409 615 GGTREAVIRGLARTGRVITSAALIMAAVFAAFATSPLVFLKQIGFGLAVGVLLDAFVVRMLLVPALMALLGRWNWW 690
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
13-709 |
9.45e-49 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 185.17 E-value: 9.45e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 13 PWKIIVGWIIAAVALVAFGPQLSSVTNDNQSSFLP---SKYESVQAKNALDAEFPSTvgqvATIVIRPVGDGALSAAEQQ 89
Cdd:TIGR00833 3 AYGIIGVWIATAISLQLLAPLLEDVSYFRLQAELPggaASSIAVKEMSAAFQEAIRD----PKIILVLESNERLGDKDYA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 90 KVSDLATTLTGD--HITGVAGVQA------GQVSPKQTAQLMFAKLTADQGdQKASSDAVKALRADLAAKLNGSGMKAEV 161
Cdd:TIGR00833 79 TYDALIAKLRADimHVISVVDFWGppeaaeGLRSDDGKATIIIVNLAGEKG-QKEAQEAINAVRRIVEQTNAPDGLTVHV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 162 TGDAAMGLDTSDSSNKATGIVMMATLLLIIVLMGFIFRGVIAVLLPILSVFLVMMVSQPVIALMAKGFGLHVQSFLEIML 241
Cdd:TIGR00833 158 TGPLATIADILESGDKDMNRITATTGIIVLIILLLVYRSPITMLVPLVSVGFSVVVAQGIVSLLGIPGLIGVNAQTTVLL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 242 VVVLFGIGTDYIVFLLFRLRERLRAGDTIQQAVATTVERVGEAIASAAAAVIIAFCALGLATFKAFTSLGPALAIAVAVM 321
Cdd:TIGR00833 238 TALVIGAGTDYAVFLTGRYHEERRKGESLEEAAAEALRGTGKAILGSALTVAVAFLALSLARLPSFKTLGVSCAVGVLVA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 322 LLAGLTLVPALMVTLGTKIFWPGKkwRRVPTAGPARKVGNLVGKRPAAVAAVSFVIMAGLAVGAVGFKADYDQQSQMPGG 401
Cdd:TIGR00833 318 LLNAVTLTPALLTLEGREGLMKPG--RKSKIRFIWRRLGTAVVRRPWPILVTTLIISGVSLLALPLIRTGYDDEKMIPTD 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 402 VESTIAIKDMQKAgFAQGATAATDVIV----------------------------------TSTDGKPLDQAKLQTYADG 447
Cdd:TIGR00833 396 LESVQGYEAADRH-FPGNSMDPMVVMIksdhdvrnpalladidrfereikavpginmvqetQRPDGVVIKKTYLTFQAGN 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 448 LGA-----------------------------------------------------------------------ASPELS 456
Cdd:TIGR00833 475 LGDqldefsdqltsrqayllqdaekiaeaiaglrlvqagmrldgenlgqvslavrlmqqaisklqgsagdvfdiFDPLRR 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 457 GLMPFPVKPGSPA----------------------------------------------------GTKGATVEYNQA--- 481
Cdd:TIGR00833 555 FVAAIPECRANPVcsvareivqaadtvvssaakladaagqlargiadvasalsqvsglpnaldgiGTQLAQMRESAAgvq 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 482 ------------------------------------------------GTAAHIQVLTKDSPFAAAAMSAVDGPLKSAAH 513
Cdd:TIGR00833 635 dllnelsdysmtmgklkgnamgvdfyappriftdpnfkavldyflspdGHAARLLVYGDGSPAGDQGAQEFNAIRTVAEE 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 514 STVPA---GAKALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVLALQLRALVAPLYLMVAVGLGYTGTLGASVLMFQ 590
Cdd:TIGR00833 715 AIQRAdlePAKVELAGVSAVNRDLRDLVNSDLGLISIITLAIVFMILALLLRAPVAPIVLIGSVALSYLWALGLSVLAFQ 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 591 TVQNKpGMMFMLPVMVYLFVVAIGTDYNILMISRLREEAREGhdPRRAAALAVEHAGPSVASAGLILAGTFASLMLGGLA 670
Cdd:TIGR00833 795 HILGA-ELHWSVLAGVFVLLVALGVDYNMLLVSRIKEESPAG--NRTGIIRALGSTGGVITAAGLVFAGTMAALASAQLT 871
|
890 900 910
....*....|....*....|....*....|....*....
gi 502434125 671 MMQQIGFAVSFGISIAAFVMSMFLVPAVTALMGAKAWWP 709
Cdd:TIGR00833 872 AIAQFGFTVGVGILLDTFIVRSVTVPALTLLLGRWIWWP 910
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
399-725 |
4.05e-41 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 153.22 E-value: 4.05e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 399 PGGVESTIAIKDMQKAgFAQGATAATDVIVTSTDGKPLDQAKLQTYADGLGAASPELSGLMPFPVKPGSPAGTKGATVey 478
Cdd:pfam03176 4 PADAPSVRAMDRLGAA-FPQADSDPIIVVVLGEGDQALGDAAAEAGYDTLVDALRADTGHVGSVQDFWGDPDTAALFV-- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 479 NQAGTAAHIQVLTKDSPFAAAAMSAVDGPLKSAAHSTVPAGAKALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVLA 558
Cdd:pfam03176 81 SPDGKAAYVVVTLEGDPGTTEADESVAAVRDAVEQAPPPEGLKAYLTGPAATVADLRDAGDRDLGLIEAVTLVVIFIILL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 559 LQLRALVAPLYLMVAVGLGYTGTLGaSVLMFQTVQNKPGMMFMLPVMVyLFVVAIGTDYNILMISRLREEAREGHDPRRA 638
Cdd:pfam03176 161 IVYRSVVAALLPLLTVGLSLGAAQG-LVAILAHILGIGLSTFALNLLV-VLLIAVGTDYALFLVSRYREELRAGEDREEA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 639 AALAVEHAGPSVASAGLILAGTFASLMLGGLAMMQQIGFAVSFGISIAAFVmSMFLVPAVTALMGAKAWWPGHKGVA--- 715
Cdd:pfam03176 239 VIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLA-ALTLLPALLALLGRWGLWPPKRDRTarw 317
|
330
....*....|...
gi 502434125 716 ---SATAGVGRPV 725
Cdd:pfam03176 318 wrrIGRLVVRRPA 330
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
563-716 |
2.59e-05 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 47.53 E-value: 2.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 563 ALVAPLYLMVAV--GLGYTGTLgasvlmfqtvqnkPGMMFmlpvmvylFVVAIGT--DYNILMISRLREEAREGHDPRRA 638
Cdd:PRK05812 328 ALVANLVLILAVlsLLGATLTL-------------PGIAG--------IVLTIGMavDANVLIFERIREELREGRSLRSA 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 639 AALAVEHAGPSvasaglILAGTFASLmLGGLAMMQ----QI-GFAVSFGISIAAfvmSMFlvpavTALMGAKA----WWP 709
Cdd:PRK05812 387 IEAGFKRAFST------ILDSNITTL-IAAIILYAlgtgPVkGFAVTLGIGILT---SMF-----TAITVTRAlvnlLYG 451
|
....*..
gi 502434125 710 GHKGVAS 716
Cdd:PRK05812 452 RRKRLKK 458
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
533-698 |
8.18e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 39.61 E-value: 8.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 533 DIQAANNSDLALILpVAGLLIFLVLALQLRALVAPLYLMVAVGLGYTGTLGASVLMFQT--VQNKPGMMFMlpvmvylfv 610
Cdd:NF033617 843 AFQEEGSSLLFLFL-LALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSmnIYAQIGLITL--------- 912
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 611 VAIGTDYNILMISRLREEAREGHDPRRAaalAVEHAG-----PSVASAGLILAGTFaSLMLG---GLAMMQQIGFAVSFG 682
Cdd:NF033617 913 IGLVKKNGILMVEFANELQRHQGLSRRE---AIYQAAalrlrPILMTTLAMLLGAI-PLMLStgaGAESRFPLGIVIVGG 988
|
170
....*....|....*.
gi 502434125 683 ISIAAfVMSMFLVPAV 698
Cdd:NF033617 989 LGVGT-LFTLFVLPVV 1003
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
9-708 |
1.38e-143 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 436.89 E-value: 1.38e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 9 VVHNPWKIIVGWIIAAVALVAFGPQLSSVTNDNqSSFLPSkYESVQAKNALDAEFPSTVGQVATIVIRPVGDGALSAAEQ 88
Cdd:COG2409 1 VARHRWLVLLAWLVLLVALGVLAPQLGGSLSSN-GFFLPG-SESQRAADLLAEAFPESDGASAVVVVEAPDGTLTDPAFR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 89 QKVSDLATTLTGDhiTGVAGVQ-------AGQVSPKQTAQLMFAKLTADQGDQkaSSDAVKALRaDLAAKLNGSGMKAEV 161
Cdd:COG2409 79 AAVAALVARLRAD--PGVAGVQdpwddpaAGLVSEDGKAALVTVTLDGDAGDE--AAEAVDALR-DAVAAAPAPGLTVYV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 162 TGDAAMGLDTSDSSNKATGIVMMATLLLIIVLMGFIFRGVIAVLLPILSVFLVMMVSQPVIALMAKGFGlhVQSFLEIML 241
Cdd:COG2409 154 TGPAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAAFTD--VSSFAPNLL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 242 VVVLFGIGTDYIVFLLFRLRERLRAGDTIQQAVATTVERVGEAIASAAAAVIIAFCALGLATFKAFTSLGPALAIAVAVM 321
Cdd:COG2409 232 TMLGLGVGIDYALFLVSRYREELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 322 LLAGLTLVPALMVTLGTKIFWPGKKWRRV---PTAGPARKVGNLVGKRPAAVAAVSFVIMAGLAVGAVGFKADYDQQSQM 398
Cdd:COG2409 312 VLAALTLLPALLALLGRRVFWPRRPRRRRaaaPESGFWRRLARAVVRRPVPVLVAAVAVLLALALPALGLRLGLPDADSL 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 399 PGGVESTIAIKDMQkAGFAQGATAATDVIVTST-DGKPLDQAKLQTYADGLGAaspeLSGLmpfpvkpgspAGTKGATVE 477
Cdd:COG2409 392 PADSPSRQGYDALA-EHFPPGSNGPLTVVVESDdDLDPADLAALDALAAALAA----VPGV----------ASVQPPTRP 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 478 YNQAGTAAHIQVLTKDSPFAAAAMSAVDgPLKSAAHSTVPaGAKALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVL 557
Cdd:COG2409 457 EGTDGDAARLQVVPDGDPDSPEAIDLVD-RLRDAAAPALE-GAEVLVGGTTAVNIDISDALADDLPLVIPVVLGLIFLLL 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 558 ALQLRALVAPLYLMVAVGLGYTGTLGASVLMFQTVQ-----NKPGMMFMLPVMVYLFVVAIGTDYNILMISRLREEAREG 632
Cdd:COG2409 535 LLLFRSVVAPLKAVLTNLLSLGAALGVLVLVFQHGWlllgfTPGPLDSFVPLLLFVILFGLGMDYEVFLVSRIREEYDRG 614
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502434125 633 HDPRRAAALAVEHAGPSVASAGLILAGTFASLMLGGLAMMQQIGFAVSFGISIAAFVMSMFLVPAVTALMGAKAWW 708
Cdd:COG2409 615 GGTREAVIRGLARTGRVITSAALIMAAVFAAFATSPLVFLKQIGFGLAVGVLLDAFVVRMLLVPALMALLGRWNWW 690
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
1-698 |
3.48e-55 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 202.40 E-value: 3.48e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 1 MFGRLGRFVVHNPWKIIVGWIIAAVALVAFGPQLSsvTNDNQSSFLPSKYESVQAKNALDAEFPStvGQVATIVIRPVGD 80
Cdd:COG1033 3 LMERLARFILRHRKLVLLLFLLLTLLLAYGAPKLE--VDTDFESLLPEDDPSVQAYDEFEEEFGG--DDTVVVAVEGKDD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 81 ----GALSAAEQ-----------QKVSDLA----TTLTGDHITGVA------------------------GVQAGQVSPK 117
Cdd:COG1033 79 iftpETLEALRElteeleeipgvDSVTSLTnvraTEGTEDGLTVEPlipdelpaspeelaelrekvlsspLYVGRLVSPD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 118 QTAQLMFAKLTAD-QGDQKASSDAVKALRAdLAAKLNGSGMKAEVTGDAAMGLDTSDSSNKATGIVMMATLLLIIVLMGF 196
Cdd:COG1033 159 GKATLIVVTLDPDpLSSDLDRKEVVAEIRA-IIAKYEDPGVEVYLTGFPVLRGDIAEAIQSDLAIFFPLALLLILLLLFL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 197 IFRGVIAVLLPILSVFLVMMVSQPVIALMakGFGLhvqSFLEIMLVVVLFGIGTDYIVFLLFRLRERLRAGDTIQQAVAT 276
Cdd:COG1033 238 FFRSLRGVLLPLLVVLLAVIWTLGLMGLL--GIPL---SPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALRE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 277 TVERVGEAIASAAAAVIIAFCALGLATFKAFTSLGPALAIAVAVMLLAGLTLVPALMVTLGTKIFWPGKKWRRVPTAGPA 356
Cdd:COG1033 313 ALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 357 RKVGNLVGKRPAAVAAVSFVIMAGLAVGAVGFKADYDQQSQMPGGVESTIAIKDMQKAgFaqGATAATDVIVTSTDGKPL 436
Cdd:COG1033 393 AKLARFVLRRPKVILVVALVLAVVSLYGISRLKVEYDFEDYLPEDSPIRQDLDFIEEN-F--GGSDPLEVVVDTGEPDGL 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 437 DQA-------KLQTYADGLGAASPELS--------------GLMPFPVKPGSPAGTKGATVEY------------NQAGT 483
Cdd:COG1033 470 KDPevlkeidRLQDYLESLPEVGKVLSladlvkelnqalneGDPKYYALPESRELLAQLLLLLssppgddlsrfvDEDYS 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 484 AAHIQVLTKDSPfaAAAMSAVDGPLKSAAHSTVP-AGAKALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVLALQLR 562
Cdd:COG1033 550 AARVTVRLKDLD--SEEIKALVEEVRAFLAENFPpDGVEVTLTGSAVLFAAINESVIESQIRSLLLALLLIFLLLLLAFR 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 563 ALVAPLYLMVAVGLGYTGTLGASVLMfqtvqnkpGM-MFMLPVMVylFVVAIGT--DYNILMISRLREEAREGHDPRRAA 639
Cdd:COG1033 628 SLRLGLISLIPNLLPILLTFGLMGLL--------GIpLNIATAVV--ASIALGIgvDYTIHFLSRYREERRKGGDLEEAI 697
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 502434125 640 ALAVEHAGPSVASAGLILAGTFASLMLGGLAMMQQIGFAVSFGIsIAAFVMSMFLVPAV 698
Cdd:COG1033 698 RRALRTTGKAILFTSLTLAAGFGVLLFSSFPPLADFGLLLALGL-LVALLAALLLLPAL 755
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
13-709 |
9.45e-49 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 185.17 E-value: 9.45e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 13 PWKIIVGWIIAAVALVAFGPQLSSVTNDNQSSFLP---SKYESVQAKNALDAEFPSTvgqvATIVIRPVGDGALSAAEQQ 89
Cdd:TIGR00833 3 AYGIIGVWIATAISLQLLAPLLEDVSYFRLQAELPggaASSIAVKEMSAAFQEAIRD----PKIILVLESNERLGDKDYA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 90 KVSDLATTLTGD--HITGVAGVQA------GQVSPKQTAQLMFAKLTADQGdQKASSDAVKALRADLAAKLNGSGMKAEV 161
Cdd:TIGR00833 79 TYDALIAKLRADimHVISVVDFWGppeaaeGLRSDDGKATIIIVNLAGEKG-QKEAQEAINAVRRIVEQTNAPDGLTVHV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 162 TGDAAMGLDTSDSSNKATGIVMMATLLLIIVLMGFIFRGVIAVLLPILSVFLVMMVSQPVIALMAKGFGLHVQSFLEIML 241
Cdd:TIGR00833 158 TGPLATIADILESGDKDMNRITATTGIIVLIILLLVYRSPITMLVPLVSVGFSVVVAQGIVSLLGIPGLIGVNAQTTVLL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 242 VVVLFGIGTDYIVFLLFRLRERLRAGDTIQQAVATTVERVGEAIASAAAAVIIAFCALGLATFKAFTSLGPALAIAVAVM 321
Cdd:TIGR00833 238 TALVIGAGTDYAVFLTGRYHEERRKGESLEEAAAEALRGTGKAILGSALTVAVAFLALSLARLPSFKTLGVSCAVGVLVA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 322 LLAGLTLVPALMVTLGTKIFWPGKkwRRVPTAGPARKVGNLVGKRPAAVAAVSFVIMAGLAVGAVGFKADYDQQSQMPGG 401
Cdd:TIGR00833 318 LLNAVTLTPALLTLEGREGLMKPG--RKSKIRFIWRRLGTAVVRRPWPILVTTLIISGVSLLALPLIRTGYDDEKMIPTD 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 402 VESTIAIKDMQKAgFAQGATAATDVIV----------------------------------TSTDGKPLDQAKLQTYADG 447
Cdd:TIGR00833 396 LESVQGYEAADRH-FPGNSMDPMVVMIksdhdvrnpalladidrfereikavpginmvqetQRPDGVVIKKTYLTFQAGN 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 448 LGA-----------------------------------------------------------------------ASPELS 456
Cdd:TIGR00833 475 LGDqldefsdqltsrqayllqdaekiaeaiaglrlvqagmrldgenlgqvslavrlmqqaisklqgsagdvfdiFDPLRR 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 457 GLMPFPVKPGSPA----------------------------------------------------GTKGATVEYNQA--- 481
Cdd:TIGR00833 555 FVAAIPECRANPVcsvareivqaadtvvssaakladaagqlargiadvasalsqvsglpnaldgiGTQLAQMRESAAgvq 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 482 ------------------------------------------------GTAAHIQVLTKDSPFAAAAMSAVDGPLKSAAH 513
Cdd:TIGR00833 635 dllnelsdysmtmgklkgnamgvdfyappriftdpnfkavldyflspdGHAARLLVYGDGSPAGDQGAQEFNAIRTVAEE 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 514 STVPA---GAKALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVLALQLRALVAPLYLMVAVGLGYTGTLGASVLMFQ 590
Cdd:TIGR00833 715 AIQRAdlePAKVELAGVSAVNRDLRDLVNSDLGLISIITLAIVFMILALLLRAPVAPIVLIGSVALSYLWALGLSVLAFQ 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 591 TVQNKpGMMFMLPVMVYLFVVAIGTDYNILMISRLREEAREGhdPRRAAALAVEHAGPSVASAGLILAGTFASLMLGGLA 670
Cdd:TIGR00833 795 HILGA-ELHWSVLAGVFVLLVALGVDYNMLLVSRIKEESPAG--NRTGIIRALGSTGGVITAAGLVFAGTMAALASAQLT 871
|
890 900 910
....*....|....*....|....*....|....*....
gi 502434125 671 MMQQIGFAVSFGISIAAFVMSMFLVPAVTALMGAKAWWP 709
Cdd:TIGR00833 872 AIAQFGFTVGVGILLDTFIVRSVTVPALTLLLGRWIWWP 910
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
399-725 |
4.05e-41 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 153.22 E-value: 4.05e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 399 PGGVESTIAIKDMQKAgFAQGATAATDVIVTSTDGKPLDQAKLQTYADGLGAASPELSGLMPFPVKPGSPAGTKGATVey 478
Cdd:pfam03176 4 PADAPSVRAMDRLGAA-FPQADSDPIIVVVLGEGDQALGDAAAEAGYDTLVDALRADTGHVGSVQDFWGDPDTAALFV-- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 479 NQAGTAAHIQVLTKDSPFAAAAMSAVDGPLKSAAHSTVPAGAKALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVLA 558
Cdd:pfam03176 81 SPDGKAAYVVVTLEGDPGTTEADESVAAVRDAVEQAPPPEGLKAYLTGPAATVADLRDAGDRDLGLIEAVTLVVIFIILL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 559 LQLRALVAPLYLMVAVGLGYTGTLGaSVLMFQTVQNKPGMMFMLPVMVyLFVVAIGTDYNILMISRLREEAREGHDPRRA 638
Cdd:pfam03176 161 IVYRSVVAALLPLLTVGLSLGAAQG-LVAILAHILGIGLSTFALNLLV-VLLIAVGTDYALFLVSRYREELRAGEDREEA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 639 AALAVEHAGPSVASAGLILAGTFASLMLGGLAMMQQIGFAVSFGISIAAFVmSMFLVPAVTALMGAKAWWPGHKGVA--- 715
Cdd:pfam03176 239 VIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLA-ALTLLPALLALLGRWGLWPPKRDRTarw 317
|
330
....*....|...
gi 502434125 716 ---SATAGVGRPV 725
Cdd:pfam03176 318 wrrIGRLVVRRPA 330
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
363-723 |
7.12e-38 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 150.69 E-value: 7.12e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 363 VGKRPAAVAAVSFVIMAGLAVGAVGFKADYDQQSQMPGGVESTIAIkDMQKAGFAQGATAATDVIVTSTDGKPLDQAKLQ 442
Cdd:COG2409 1 VARHRWLVLLAWLVLLVALGVLAPQLGGSLSSNGFFLPGSESQRAA-DLLAEAFPESDGASAVVVVEAPDGTLTDPAFRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 443 TYADGLG--AASPELSGLMPFPVKPGSPAgtkgatveYNQAGTAAHIQVlTKDSPFAAAAMSAVDgPLKSAAHSTVPAGA 520
Cdd:COG2409 80 AVAALVArlRADPGVAGVQDPWDDPAAGL--------VSEDGKAALVTV-TLDGDAGDEAAEAVD-ALRDAVAAAPAPGL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 521 KALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVLALQLRALVAPLYLMVAVGLGYTGTLGASVLMFQTVqnkpGMMF 600
Cdd:COG2409 150 TVYVTGPAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAAFT----DVSS 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 601 MLPVMVYLFVVAIGTDYNILMISRLREEAREGHDPRRAAALAVEHAGPSVASAGLILAGTFASLMLGGLAMMQQIGFAVS 680
Cdd:COG2409 226 FAPNLLTMLGLGVGIDYALFLVSRYREELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAA 305
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 502434125 681 FGISIAAFVmSMFLVPAVTALMGAKAWWPGHKGVASATAGVGR 723
Cdd:COG2409 306 IGVAVAVLA-ALTLLPALLALLGRRVFWPRRPRRRRAAAPESG 347
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
44-370 |
1.63e-35 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 137.42 E-value: 1.63e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 44 SFLPSKYESVQAKNALDAEFPSTVGQVATIVIRPVGDGALSAAEQQK-VSDLATTLTGDHiTGVAGVQ---------AGQ 113
Cdd:pfam03176 1 ALSPADAPSVRAMDRLGAAFPQADSDPIIVVVLGEGDQALGDAAAEAgYDTLVDALRADT-GHVGSVQdfwgdpdtaALF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 114 VSPKQTAQLMFAKLTADQGDQkASSDAVKALRADLAAKLNGSGMKAEVTGDAAMGLDTSDSSNKATGIVMMATLLLIIVL 193
Cdd:pfam03176 80 VSPDGKAAYVVVTLEGDPGTT-EADESVAAVRDAVEQAPPPEGLKAYLTGPAATVADLRDAGDRDLGLIEAVTLVVIFII 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 194 MGFIFRGVIAVLLPILSVFLVMMVSQPVIALMAKGFGLHVQSFLEIMLVVVLFGIGTDYIVFLLFRLRERLRAGDTIQQA 273
Cdd:pfam03176 159 LLIVYRSVVAALLPLLTVGLSLGAAQGLVAILAHILGIGLSTFALNLLVVLLIAVGTDYALFLVSRYREELRAGEDREEA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 274 VATTVERVGEAIASAAAAVIIAFCALGLATFKAFTSLGPALAIAVAVMLLAGLTLVPALMVTLGTKIFWPGkkwRRVPTA 353
Cdd:pfam03176 239 VIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLAALTLLPALLALLGRWGLWPP---KRDRTA 315
|
330
....*....|....*..
gi 502434125 354 GPARKVGNLVGKRPAAV 370
Cdd:pfam03176 316 RWWRRIGRLVVRRPAPV 332
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
114-701 |
5.67e-30 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 126.49 E-value: 5.67e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 114 VSPKQTAQLMFAKLTADQgDQKASSDAVKALRADLAAKLNGSGMKAEVTGDAAMGLDTSDSSNKATGIVMMATLLLIIVL 193
Cdd:TIGR00921 131 LSKDHTVAIIIVQLKSDA-DYKQVVPIYNDVERSLERTNPPSGKFLDVTGSPAINYDIEREFGKDMGTTMAISGILVVLV 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 194 MGFIFRGVIAVLLPILSVFLVMMVSQPVIALMAKGFGLHVqsfleIMLVVVLFGIGTDYIVFLLFRLRERLRAGDTIQQA 273
Cdd:TIGR00921 210 LLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATT-----LLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEA 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 274 VATTVERVGEAIASAAAAVIIAFCALGLATFKAFTSLGPALAIAVAVMLLAGLTLVPALMVTLgtKIFWPGKKWRRVPTA 353
Cdd:TIGR00921 285 IVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLPALLQSI--DIGREKVKKEIIAIG 362
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 354 GPA-------RKVGNLVGKRPAAVAAVSFVIMAGLAVGAVGFKADYDQQSQMPGGVESTIAIKDMQKagFAQGATAATDV 426
Cdd:TIGR00921 363 GKSseieeelSKVLSITVRHPVPALVAALIITGLGLYGAAGIKPEVNIEKFIPQDLPSLQARKVIES--HMGGSHDFATI 440
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 427 IVTSTDG------KPLDQAKLQTYADG-----LGAAS-----PELSGLMPFPVKPGS--PAGTKGATVEYNQAGTAAHIQ 488
Cdd:TIGR00921 441 LVKADDVrdpelvRFMDELSRDIKATGvaarvFGAPSiidlvKEVEGLPAPERSALEpiPEDEEGGYISGGQIKVAVIQV 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 489 VLTKDSPfaaaaMSAVDGPLKSAAHSTVPAGAKALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVLALQLRALVAPL 568
Cdd:TIGR00921 521 QLKQGEP-----KVQGRKILRDVQHEHPPPGVKVGVTGLPVAFAEMHELVNEGMRRMTIAGAILVLMILLAVFRNPIKAV 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 569 YLMVAVGLGYTGTLGasvLMFQTVQNKPGMMFMLPVMvylfVVAIGTDYNILMISRLREEaREGHDPRRAAALAVEHAGP 648
Cdd:TIGR00921 596 FPLIAIGSGILWAIG---LMGLRGIPSFLAMATTISI----ILGLGMDYSIHLAERYFEE-RKEHGPKEAITHTMERTGP 667
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 502434125 649 SVASAGLILAGTFASLMLGGLAMMQQIGFAVSFGIsIAAFVMSMFLVPAVTAL 701
Cdd:TIGR00921 668 GILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGV-LSSLTAALVVFPALLVL 719
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
357-707 |
2.19e-27 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 118.42 E-value: 2.19e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 357 RKVGNLVGKRPAAVAAVSFVIMAGLAVGAVGFKADYDQQSQMPGGVESTIAIKDMQKAgFAQGATAatdVIVTSTDGKPL 436
Cdd:COG1033 5 ERLARFILRHRKLVLLLFLLLTLLLAYGAPKLEVDTDFESLLPEDDPSVQAYDEFEEE-FGGDDTV---VVAVEGKDDIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 437 DQAKLQTYAD------------------GLGAASPELSGLMPFPVKPGSPAGTKGATVE---------------YNQAGT 483
Cdd:COG1033 81 TPETLEALRElteeleeipgvdsvtsltNVRATEGTEDGLTVEPLIPDELPASPEELAElrekvlssplyvgrlVSPDGK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 484 AAHIQV-LTKDSPFAAAAMSAVDGPLKSAAHSTVPAGAKALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVLALQLR 562
Cdd:COG1033 161 ATLIVVtLDPDPLSSDLDRKEVVAEIRAIIAKYEDPGVEVYLTGFPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 563 ALVAPLYLMVAVGLGYTGTLGASVLMFQTVQNkpgMMFMLPVMVylfvVAIGTDYNILMISRLREEAREGHDPRRAAALA 642
Cdd:COG1033 241 SLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSP---LTILVPPLL----LAIGIDYGIHLLNRYREERRKGLDKREALREA 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 502434125 643 VEHAGPSVASAGLILAGTFASLMLGGLAMMQQIGFAVSFGIsIAAFVMSMFLVPAVTALMGAKAW 707
Cdd:COG1033 314 LRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGV-LLAFLTSLTLLPALLSLLPRPKP 377
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
1-348 |
4.44e-27 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 117.17 E-value: 4.44e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 1 MFGRLGRFVVHNPWKIIVGWIIAAVALVAFGPQLSsvTNDNQSSFLPSKYESVQAKNALDAEFPSTVGQVATIVIRpvGD 80
Cdd:COG2409 348 FWRRLARAVVRRPVPVLVAAVAVLLALALPALGLR--LGLPDADSLPADSPSRQGYDALAEHFPPGSNGPLTVVVE--SD 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 81 GALSAAEQQKVSDLATTLTgdHITGVAGVQAGQVSPKQ--TAQLMFAKLTADQGDQkASSDAVKALRADLAAKLNGSgmK 158
Cdd:COG2409 424 DDLDPADLAALDALAAALA--AVPGVASVQPPTRPEGTdgDAARLQVVPDGDPDSP-EAIDLVDRLRDAAAPALEGA--E 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 159 AEVTGDAAMGLDTSDSSNKATGIVMMATLLLIIVLMGFIFRGVIAVLLPILSVFLVMMVSQPVIALM----AKGFGLH-- 232
Cdd:COG2409 499 VLVGGTTAVNIDISDALADDLPLVIPVVLGLIFLLLLLLFRSVVAPLKAVLTNLLSLGAALGVLVLVfqhgWLLLGFTpg 578
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 233 -VQSFLEIMLVVVLFGIGTDYIVFLLFRLRERLRAGDTIQQAVATTVERVGeaiasaaaaviiafcalGL---------A 302
Cdd:COG2409 579 pLDSFVPLLLFVILFGLGMDYEVFLVSRIREEYDRGGGTREAVIRGLARTG-----------------RVitsaalimaA 641
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 502434125 303 TFKAFTSLGP------ALAIAVAVMLLAGL---TLVPALMVTLGTKIFW-PGKKWR 348
Cdd:COG2409 642 VFAAFATSPLvflkqiGFGLAVGVLLDAFVvrmLLVPALMALLGRWNWWlPRWLDR 697
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
2-340 |
1.29e-19 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 93.77 E-value: 1.29e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 2 FGRLGRFVVHNPWKIIVGWIIAAVALVAFGPQLSsvTNDNQSSFLPSKYESVQAKNALDAEFPSTvgQVATIVIR-PVGD 80
Cdd:COG1033 392 LAKLARFVLRRPKVILVVALVLAVVSLYGISRLK--VEYDFEDYLPEDSPIRQDLDFIEENFGGS--DPLEVVVDtGEPD 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 81 GALSAAEQQKVSDLATTL-TGDHITGV-----------AGVQAGQV-------SPKQTAQLMFAKLTADQGD-------- 133
Cdd:COG1033 468 GLKDPEVLKEIDRLQDYLeSLPEVGKVlsladlvkelnQALNEGDPkyyalpeSRELLAQLLLLLSSPPGDDlsrfvded 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 134 --------------QKASSDAVKALRADLAAKLNGSGMKAEVTGDAAMGLDTSDSSNKATGIVMMATLLLIIVLMGFIFR 199
Cdd:COG1033 548 ysaarvtvrlkdldSEEIKALVEEVRAFLAENFPPDGVEVTLTGSAVLFAAINESVIESQIRSLLLALLLIFLLLLLAFR 627
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 200 GVIAVLLPILSVFLVMMVsqpVIALMAKgFGLHVqSFLEIMLVVVLFGIGTDYIVFLLFRLRERLRAGDTIQQAVATTVE 279
Cdd:COG1033 628 SLRLGLISLIPNLLPILL---TFGLMGL-LGIPL-NIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALR 702
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 502434125 280 RVGEAIASAAAAVIIAFCALGLATFKAFTSLGPALAIAVAVMLLAGLTLVPALMVTLGTKI 340
Cdd:COG1033 703 TTGKAILFTSLTLAAGFGVLLFSSFPPLADFGLLLALGLLVALLAALLLLPALLLLLDPRI 763
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
499-702 |
1.46e-08 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 58.19 E-value: 1.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 499 AAMSAVDgplKSAAHSTVPAGAKALVGGgtaaLSDIQAANNSDLALILPVAGLLIFLVLALQLRALVAPLYLMVAVGLGY 578
Cdd:COG0841 817 EALAAIE---ELAAELKLPPGVSIEFTG----QAEEEQESFSSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLAL 889
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 579 TGTLGASVLMFQTVqnkpGMMFMLPVMVylfVVAIGTDYNILMISRLREEAREGHDPRRAAalavEHAGP---------S 649
Cdd:COG0841 890 IGALLGLLLTGTPL----NIYSQIGLIM---LIGIVVKNAILLVDFANQLREEGMSLREAI----LEAARlrlrpilmtS 958
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 502434125 650 VAS-AGLIlagtfaSLMLG---GLAMMQQIGFAVSFGISIAAFVmSMFLVPAVTALM 702
Cdd:COG0841 959 LATiLGLL------PLALGtgaGAEFRQPLGIAVIGGLLFSTLL-TLFVVPVLYVLL 1008
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
2-334 |
4.48e-08 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 56.77 E-value: 4.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 2 FGRLGRFVVHNPWKIIVGWIIAAVALVAFGPQLSSVTNDNqsSFLPSKYESVQAKNALDAEFPSTVGQVATIV-IRPVGD 80
Cdd:TIGR00921 372 LSKVLSITVRHPVPALVAALIITGLGLYGAAGIKPEVNIE--KFIPQDLPSLQARKVIESHMGGSHDFATILVkADDVRD 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 81 GAL----SAAEQQKVSD--LATTLTGDHITGVAGVQAGQVSPKQTAqlmFAKLTADQGDQKASSDAVKALRADLAAKLNG 154
Cdd:TIGR00921 450 PELvrfmDELSRDIKATgvAARVFGAPSIIDLVKEVEGLPAPERSA---LEPIPEDEEGGYISGGQIKVAVIQVQLKQGE 526
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 155 ------------------SGMKAEVTGDAAMGLDTSDSSNkaTGIVMMATLLLIIVLMGF--IFRGVIAVLLPILSVFLV 214
Cdd:TIGR00921 527 pkvqgrkilrdvqhehppPGVKVGVTGLPVAFAEMHELVN--EGMRRMTIAGAILVLMILlaVFRNPIKAVFPLIAIGSG 604
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 215 MMVSQPVIALMAKGFGLHVQSfleimLVVVLFGIGTDYIVFLLFRLRERLRAgDTIQQAVATTVERVGEAIASAAAAVII 294
Cdd:TIGR00921 605 ILWAIGLMGLRGIPSFLAMAT-----TISIILGLGMDYSIHLAERYFEERKE-HGPKEAITHTMERTGPGILFSGLTTAG 678
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 502434125 295 AFCALGLATFKAFTSLGPALAIAVAVMLLAGLTLVPALMV 334
Cdd:TIGR00921 679 GFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFPALLV 718
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
527-718 |
8.98e-06 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 49.23 E-value: 8.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 527 GTAALSDIQAANNSD---LALILPVAGLLIFLVLALQLRALVAPLYLMVAVGLGYTGTLGASVLmfqtvqnkpGMMFMLP 603
Cdd:TIGR03480 255 GEVALSDEELATVSEgatVAGLLSFVLVLVLLWLALRSPRLVFAVLVTLIVGLILTAAFATLAV---------GHLNLIS 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 604 VMVYLFVVAIGTDYNILMISRLREEAREGHDPRRAAALAVEHAGPSVASAGLILAGTFASLMLGGLAMMQQIGFAVSFGI 683
Cdd:TIGR03480 326 VAFAVLFIGLGVDFAIQFSLRYREERFRGGNHREALSVAARRMGAALLLAALATAAGFFAFLPTDYKGVSELGIIAGTGM 405
|
170 180 190
....*....|....*....|....*....|....*
gi 502434125 684 SIAAFVmSMFLVPAVTALMGAKawwPGHKGVASAT 718
Cdd:TIGR03480 406 FIALFV-TLTVLPALLRLLRPP---RRRKPPGYAT 436
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
563-716 |
2.59e-05 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 47.53 E-value: 2.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 563 ALVAPLYLMVAV--GLGYTGTLgasvlmfqtvqnkPGMMFmlpvmvylFVVAIGT--DYNILMISRLREEAREGHDPRRA 638
Cdd:PRK05812 328 ALVANLVLILAVlsLLGATLTL-------------PGIAG--------IVLTIGMavDANVLIFERIREELREGRSLRSA 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 639 AALAVEHAGPSvasaglILAGTFASLmLGGLAMMQ----QI-GFAVSFGISIAAfvmSMFlvpavTALMGAKA----WWP 709
Cdd:PRK05812 387 IEAGFKRAFST------ILDSNITTL-IAAIILYAlgtgPVkGFAVTLGIGILT---SMF-----TAITVTRAlvnlLYG 451
|
....*..
gi 502434125 710 GHKGVAS 716
Cdd:PRK05812 452 RRKRLKK 458
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
549-702 |
6.53e-05 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 46.52 E-value: 6.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 549 AGLLIFLVLALQLRALVAPLYLMVAVGLGYTGTLgASVLMFQTVQNKPGMMFMlpvmvylfVVAIG--TDYNILMISRLR 626
Cdd:pfam00873 340 AIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTF-AVMKAFGFSINTLTLGGL--------VLAIGlvVDDAIVVVENIE 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 627 EEAREGHDPRRAAAL--AVEHAGPSVASAGLILAGTFASLMLGGL--AMMQQIGFAVSFGISIAAFVmSMFLVPAVTALM 702
Cdd:pfam00873 411 RVLEENGLKPLEAAYksMGEIGGALVAIALVLSAVFLPILFLGGLtgRIFRQFAITIVLAILLSVLV-ALTLTPALCATL 489
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
542-706 |
1.11e-04 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 45.79 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 542 LALILPVAGLLIFLVLALQLRALVAPLYLMVAVGLGYTGTLGASVLMfqtvqnkpGMMFMLPVMV---YLFVVAIGTDyn 618
Cdd:COG3696 866 LAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLR--------GMPLSVSAGVgfiALFGVAVLNG-- 935
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 619 ILMISRLREEAREGHDPRRAAAL-AVEHAGP-----SVASAGLI-LA---GT-------FASLMLGGLammqqigfavsf 681
Cdd:COG3696 936 VVLVSYINQLRAEGLDLREAIIEgALERLRPvlmtaLVAALGLLpMAlstGPgsevqrpLATVVIGGL------------ 1003
|
170 180
....*....|....*....|....*
gi 502434125 682 gisIAAFVMSMFLVPAVTALMGAKA 706
Cdd:COG3696 1004 ---ITSTLLTLLVLPALYLLFGRRR 1025
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
480-698 |
9.81e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 42.53 E-value: 9.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 480 QAGTAAHIQVLTKDSPFAAAAMSAVDGPLKSA--AHSTVPAGAKALVGGGTAALSDIQAANNSDLALILPVAGLLIFLVL 557
Cdd:COG4258 187 RDGTWALLLAETRASGFDTDAQQQLVAALRAAfaALNAAFPGAQLLLTGAGLFAVAAAQQIKHDISTIGLISLLGILLLL 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 558 ALQLRALVAPLYLMVAVGLGYTGTLGASVLMFQTvqnkpgmmfmlpvmVYLFVVAIGT-------DYNILMISRLReeAR 630
Cdd:COG4258 267 LLVFRSLRPLLLGLLPVAVGALAGLAAVSLVFGS--------------VHGITLGFGSsligvavDYSLHYLTHRR--AA 330
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 502434125 631 EGHDPRRAAAlaveHAGPSVASAGLILAGTFASLMLGGLAMMQQIG-FAVSfGIsIAAFVMSMFLVPAV 698
Cdd:COG4258 331 GEWDPRAALR----RIWPTLLLGLLTTVLGYLALLFSPFPGLRQLGvFAAA-GL-LAAALTTLLWLPLL 393
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
543-706 |
1.11e-03 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 41.89 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 543 ALILPVAGLLIFLVLALQLR------ALVAPLYLMVAV--GLGYTGTLgasvlmfqtvqnkPGMMFMlpvmvylfVVAIG 614
Cdd:TIGR01129 253 AGLIGLVLVLVFMILYYRLFgliaaiALVINIVLILAIlsAFGATLTL-------------PGIAGL--------ILTIG 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 615 T--DYNILMISRLREEAREGHDPRRAAALAVEHAGPSVASAGLIlagTF-ASLMLGGLAMMQQIGFAVSFGISIAAfvmS 691
Cdd:TIGR01129 312 MavDANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANIT---TLiAALILYVFGTGPVKGFAVTLAIGIIA---S 385
|
170
....*....|....*
gi 502434125 692 MFlvpavTALMGAKA 706
Cdd:TIGR01129 386 LF-----TALVFTRL 395
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
500-701 |
1.17e-03 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 42.28 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 500 AMSAVDgplKSAAHSTVPAGAKALVGGGTAALsdiQAANNSDLALIlPVAGLLIFLVLALQLRALVAPLYLMVAVGLGYT 579
Cdd:pfam00873 829 AMEAMA---QIAKQVKLPPGYGYTWTGQFEQE---QLAGNSLPILI-ALALLVVFLVLAALYESWSDPLSIMLTVPLALV 901
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 580 GTLGASVLMfqtvqnkpGMMFMLPVMVYlFVVAIGTDYN--ILMISRLRE-EAREGHDPRRAAALAVEHAGPSVASAGLI 656
Cdd:pfam00873 902 GALLALWLR--------GLPNSVYAQVG-LILLIGLAVKnaILMVEFANElREQEGKSLEEAILEACRLRLRPILMTALA 972
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 502434125 657 LAGTFASLMLG---GLAMMQQIGFAVSFGISIAAFvMSMFLVPAVTAL 701
Cdd:pfam00873 973 AILGVLPLALStgaGSELQQPLGIVVFGGLVTSTV-LTLLVVPVFYVL 1019
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
520-700 |
1.47e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 42.15 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 520 AKALVGGGTAALSDIQAANNS-------DLALILPVAGLLIFLVLALQLRALVAPLYLMVAVGLGYTGTLGASVLMFQTV 592
Cdd:COG4258 612 RAAAAGLPGVRLVDRKAESSSlfgryrnDALWLLLLALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPL 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 593 QnkpgmmfMLPVMVYLFVVAIGTDYNILMISRLReeaREGHDPRRAAALAVehagpSVASAGLilagTFASLMLGGLAMM 672
Cdd:COG4258 692 N-------LFHLIALLLVLGIGIDYALFFTEGLL---DKGELARTLLSILL-----AALTTLL----GFGLLAFSSTPAL 752
|
170 180
....*....|....*....|....*...
gi 502434125 673 QQIGFAVSFGIsIAAFVMSMFLVPAVTA 700
Cdd:COG4258 753 RSFGLTVLLGI-LLALLLAPLLAPRRRP 779
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
622-702 |
2.10e-03 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 41.63 E-value: 2.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 622 ISRLREEareGHDPRRAAALAVEHAGPSVASAGLILAGTFASLM-LGGLA--MMQQIGFAVSFGISIAAFVmSMFLVPAV 698
Cdd:COG0841 409 IERHMEE---GLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAfMGGITgqLFRQFALTVAIALLISLFV-ALTLTPAL 484
|
....
gi 502434125 699 TALM 702
Cdd:COG0841 485 CARL 488
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
114-252 |
2.76e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 40.99 E-value: 2.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 114 VSPKQTAQLMFAKLTADQGDQKASSDAVKALRADL-AAKLNGSGMKAEVTGDAAMGLDTSDSSNKATGIVMMATLLLIIV 192
Cdd:COG4258 185 VSRDGTWALLLAETRASGFDTDAQQQLVAALRAAFaALNAAFPGAQLLLTGAGLFAVAAAQQIKHDISTIGLISLLGILL 264
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 502434125 193 LMGFIFRGVIAVLLPILSVFLVMMVSqpvIALMAKGFG-LHVqsfleIMLVV--VLFGIGTDY 252
Cdd:COG4258 265 LLLLVFRSLRPLLLGLLPVAVGALAG---LAAVSLVFGsVHG-----ITLGFgsSLIGVAVDY 319
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
548-693 |
7.83e-03 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 39.33 E-value: 7.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 548 VAGLLIFLVLALQLRA--LVAPLYLMVAVGLgytgTLGASVLMfqtvqnkpGMMFMLPVMVYlFVVAIGT--DYNILMIS 623
Cdd:COG0342 279 IGLLLVALFMLLYYRLpgLVANIALALNVVL----LLGVLSLL--------GATLTLPGIAG-IILTIGMavDANVLIFE 345
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 502434125 624 RLREEAREGHDPRRAAALAVEHAGPSVASAGL--ILAGtfASLMLGGLAMMQqiGFAVSFGISIaafVMSMF 693
Cdd:COG0342 346 RIREELRAGRSLRAAIEAGFKRAFSTILDANVttLIAA--VVLFVLGTGPVK--GFAVTLILGI---LISMF 410
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
533-698 |
8.18e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 39.61 E-value: 8.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 533 DIQAANNSDLALILpVAGLLIFLVLALQLRALVAPLYLMVAVGLGYTGTLGASVLMFQT--VQNKPGMMFMlpvmvylfv 610
Cdd:NF033617 843 AFQEEGSSLLFLFL-LALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSmnIYAQIGLITL--------- 912
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502434125 611 VAIGTDYNILMISRLREEAREGHDPRRAaalAVEHAG-----PSVASAGLILAGTFaSLMLG---GLAMMQQIGFAVSFG 682
Cdd:NF033617 913 IGLVKKNGILMVEFANELQRHQGLSRRE---AIYQAAalrlrPILMTTLAMLLGAI-PLMLStgaGAESRFPLGIVIVGG 988
|
170
....*....|....*.
gi 502434125 683 ISIAAfVMSMFLVPAV 698
Cdd:NF033617 989 LGVGT-LFTLFVLPVV 1003
|
|
| |
