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Conserved domains on  [gi|502727513|ref|WP_012962497|]
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PTS sugar transporter subunit IIA [Streptococcus gallolyticus]

Protein Classification

PTS sugar transporter subunit IIA( domain architecture ID 10082877)

PTS sugar transporter subunit IIA is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system, a major carbohydrate active transport system that catalyzes the phosphorylation of incoming sugar substrates, such as mannitol and fructose, concomitantly with their translocation across the cell membrane

CATH:  3.40.930.10
Gene Ontology:  GO:1902495|GO:0009401|GO:0016310|GO:0016301|GO:0008643
PubMed:  11532441|10393270
SCOP:  4001876

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTS_IIA_fru cd00211
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: ...
 10-140 1.00e-29

PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.


:

Pssm-ID: 238129 [Multi-domain]  Cd Length: 136  Bit Score: 104.95  E-value: 1.00e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  10 DETVNDYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFGLM 89
Cdd:cd00211    9 NLKAKSKEEAIEELAQLLVAAGYVEEEYIEALLEREKEGSTGI----GNGIAIPHAKSEAVKKPGIAVLRLKEPVDFGSL 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 502727513  90 EDKnqkvDVTLVFNLALSSGKQHIAVLRKVIALFQDDVFIKKCQK-NSVEEV 140
Cdd:cd00211   85 DGQ----PVHLIFLLAAPDSNEHLKALSQLARLLSDEEFVEQLLNaQSKEEI 132
 
Name Accession Description Interval E-value
PTS_IIA_fru cd00211
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: ...
 10-140 1.00e-29

PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.


Pssm-ID: 238129 [Multi-domain]  Cd Length: 136  Bit Score: 104.95  E-value: 1.00e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  10 DETVNDYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFGLM 89
Cdd:cd00211    9 NLKAKSKEEAIEELAQLLVAAGYVEEEYIEALLEREKEGSTGI----GNGIAIPHAKSEAVKKPGIAVLRLKEPVDFGSL 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 502727513  90 EDKnqkvDVTLVFNLALSSGKQHIAVLRKVIALFQDDVFIKKCQK-NSVEEV 140
Cdd:cd00211   85 DGQ----PVHLIFLLAAPDSNEHLKALSQLARLLSDEEFVEQLLNaQSKEEI 132
PtsN COG1762
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ...
 10-148 5.06e-27

Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 441368 [Multi-domain]  Cd Length: 150  Bit Score: 98.38  E-value: 5.06e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  10 DETVNDYQSAIRFAGEALLEVNNI--KSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFG 87
Cdd:COG1762   15 DLEASSKEEAIEELAELLAEKGYVldKEEYLEALLEREELGSTGI----GPGIAIPHARPEGVKKPGIAVARLKEPVDFG 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502727513  88 LMEDKnqkvDVTLVFNLAL--SSGKQHIAVLRKVIALFQDDVFIKK-CQKNSVEEVASDIKAKL 148
Cdd:COG1762   91 AMDGE----PVDLVFLLAApeDDSEEHLKLLAELARLLSDEEFREKlLNAKSPEEILELLKEAE 150
PTS_EIIA_2 pfam00359
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;
10-140 9.31e-24

Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;


Pssm-ID: 459780 [Multi-domain]  Cd Length: 139  Bit Score: 89.57  E-value: 9.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513   10 DETVNDYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFGLM 89
Cdd:pfam00359  10 NLEAKSKEEAIEFLADKLVEAGYVEPAYLEAILEREKEGSTGI----GNGIAIPHARSEAVKKPGIAVLTLKEPVDFGSE 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 502727513   90 EDKnqkvDVTLVFNLAL-SSGKQHIAVLRKVIALFQDDVFIKKCQK-NSVEEV 140
Cdd:pfam00359  86 DGK----PVKLIFLLAApDNEASHLKILSQLARLLQDEEFVEKLLKaKDPEEI 134
fruA TIGR00848
PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family ...
 10-131 6.17e-13

PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]


Pssm-ID: 273298 [Multi-domain]  Cd Length: 129  Bit Score: 61.52  E-value: 6.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513   10 DETVNDYQSAIRFAGEALLEVNNI--KSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFG 87
Cdd:TIGR00848  10 DQQFTSKEDVIKFLANKLLENGYIsdTEEFLEDLLKREEEGTTGI----GDGVAIPHAKSAAVKQPFVAIARLVKGVDWQ 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 502727513   88 LMEDKnqkvDVTLVFNLALS---SGKQHIAVLRKVIALFQDDVFIKK 131
Cdd:TIGR00848  86 SLDGK----PVKLIFLIAVPkdeAGNTHLKALSQLARLLLNDEFRAK 128
PRK09765 PRK09765
PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional
 17-139 1.98e-12

PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional


Pssm-ID: 182066 [Multi-domain]  Cd Length: 631  Bit Score: 63.21  E-value: 1.98e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  17 QSAIRFAGEALLEVNNI--KSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFGLMEDKNq 94
Cdd:PRK09765  22 EEAIHALAQRLAALGKIssTEQFLEEVYRRESLGPTAL----GEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPE- 96

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 502727513  95 kvDVTLVFNLAL---SSGKQHIAVLRKVIALFQDDVFIKKCQKNSVEE 139
Cdd:PRK09765  97 --AVDLIFLLAIppnEAGTTHMQLLTALTTRLADDEIRARIQSATTPD 142
 
Name Accession Description Interval E-value
PTS_IIA_fru cd00211
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: ...
 10-140 1.00e-29

PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.


Pssm-ID: 238129 [Multi-domain]  Cd Length: 136  Bit Score: 104.95  E-value: 1.00e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  10 DETVNDYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFGLM 89
Cdd:cd00211    9 NLKAKSKEEAIEELAQLLVAAGYVEEEYIEALLEREKEGSTGI----GNGIAIPHAKSEAVKKPGIAVLRLKEPVDFGSL 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 502727513  90 EDKnqkvDVTLVFNLALSSGKQHIAVLRKVIALFQDDVFIKKCQK-NSVEEV 140
Cdd:cd00211   85 DGQ----PVHLIFLLAAPDSNEHLKALSQLARLLSDEEFVEQLLNaQSKEEI 132
PtsN COG1762
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ...
 10-148 5.06e-27

Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 441368 [Multi-domain]  Cd Length: 150  Bit Score: 98.38  E-value: 5.06e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  10 DETVNDYQSAIRFAGEALLEVNNI--KSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFG 87
Cdd:COG1762   15 DLEASSKEEAIEELAELLAEKGYVldKEEYLEALLEREELGSTGI----GPGIAIPHARPEGVKKPGIAVARLKEPVDFG 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 502727513  88 LMEDKnqkvDVTLVFNLAL--SSGKQHIAVLRKVIALFQDDVFIKK-CQKNSVEEVASDIKAKL 148
Cdd:COG1762   91 AMDGE----PVDLVFLLAApeDDSEEHLKLLAELARLLSDEEFREKlLNAKSPEEILELLKEAE 150
PTS_EIIA_2 pfam00359
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;
10-140 9.31e-24

Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2;


Pssm-ID: 459780 [Multi-domain]  Cd Length: 139  Bit Score: 89.57  E-value: 9.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513   10 DETVNDYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFGLM 89
Cdd:pfam00359  10 NLEAKSKEEAIEFLADKLVEAGYVEPAYLEAILEREKEGSTGI----GNGIAIPHARSEAVKKPGIAVLTLKEPVDFGSE 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 502727513   90 EDKnqkvDVTLVFNLAL-SSGKQHIAVLRKVIALFQDDVFIKKCQK-NSVEEV 140
Cdd:pfam00359  86 DGK----PVKLIFLLAApDNEASHLKILSQLARLLQDEEFVEKLLKaKDPEEI 134
MtlA2 COG4668
Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and ...
 10-140 8.60e-19

Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism];


Pssm-ID: 443705 [Multi-domain]  Cd Length: 143  Bit Score: 77.12  E-value: 8.60e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  10 DETVNDYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLslasGQGVAMPHGNSD---FVTEDSVSVVRLSKPVAF 86
Cdd:COG4668   12 NASAANKEEAIRLAGQLLVEAGYVEPEYIDAMLEREAQVSTYL----GNGIAIPHGTNEakdLVLKTGISVLQFPDGVDW 87

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 502727513  87 GlmedKNQKvdVTLVFNLAlSSGKQHIAVLRKVIALFQDDVFIKKCQK-NSVEEV 140
Cdd:COG4668   88 G----DGNT--VYLVIGIA-AKSDEHLEILRQLARVLSDEENVEKLAKaTDAEEI 135
fruA TIGR00848
PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family ...
 10-131 6.17e-13

PTS system, fructose subfamily, IIA component; 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]


Pssm-ID: 273298 [Multi-domain]  Cd Length: 129  Bit Score: 61.52  E-value: 6.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513   10 DETVNDYQSAIRFAGEALLEVNNI--KSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFG 87
Cdd:TIGR00848  10 DQQFTSKEDVIKFLANKLLENGYIsdTEEFLEDLLKREEEGTTGI----GDGVAIPHAKSAAVKQPFVAIARLVKGVDWQ 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 502727513   88 LMEDKnqkvDVTLVFNLALS---SGKQHIAVLRKVIALFQDDVFIKK 131
Cdd:TIGR00848  86 SLDGK----PVKLIFLIAVPkdeAGNTHLKALSQLARLLLNDEFRAK 128
PRK09765 PRK09765
PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional
 17-139 1.98e-12

PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional


Pssm-ID: 182066 [Multi-domain]  Cd Length: 631  Bit Score: 63.21  E-value: 1.98e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  17 QSAIRFAGEALLEVNNI--KSDYIQACIDREVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFGLMEDKNq 94
Cdd:PRK09765  22 EEAIHALAQRLAALGKIssTEQFLEEVYRRESLGPTAL----GEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPE- 96

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 502727513  95 kvDVTLVFNLAL---SSGKQHIAVLRKVIALFQDDVFIKKCQKNSVEE 139
Cdd:PRK09765  97 --AVDLIFLLAIppnEAGTTHMQLLTALTTRLADDEIRARIQSATTPD 142
PRK15083 PRK15083
PTS system mannitol-specific transporter subunit IICBA; Provisional
 12-147 9.43e-12

PTS system mannitol-specific transporter subunit IICBA; Provisional


Pssm-ID: 237905 [Multi-domain]  Cd Length: 639  Bit Score: 61.61  E-value: 9.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  12 TVNDYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLslasGQGVAMPHGN---SDFVTEDSVSVVRLSKPVAFGL 88
Cdd:PRK15083 507 KAATKEEAIRFAGEQLVKGGYVEPEYVDAMLDREKLTSTYL----GESIAVPHGTveaKDRVLKTGVVFCQYPEGVRFGE 582

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  89 MEDKNQKvdvtLVFNLAlSSGKQHIAVLRKVI-ALFQDDVFIKKCQKNSVEEVASDIKAK 147
Cdd:PRK15083 583 EEDDIAR----LVIGIA-ARNNEHIQVITSLTnALDDESVIERLAHTTSVDEVLELLAGK 637
PRK09665 PRK09665
PTS galactitol transporter subunit IIA;
12-129 1.15e-11

PTS galactitol transporter subunit IIA;


Pssm-ID: 182023 [Multi-domain]  Cd Length: 150  Bit Score: 58.66  E-value: 1.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  12 TVNDYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLSLASgQGVAMPHGNSDFVTEDSVSVVRLSKPVAFGLMED 91
Cdd:PRK09665  11 SFVDRSEALTHIGNEMLAKGVVHDTYPQALIAREAEFPTGIMLEQ-HAVAIPHCEAIHAKSPAIYLIRPDKKVHFQQADD 89

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 502727513  92 KNQkVDVTLVFNLALSSGKQHIAVLRKVIALFQDDVFI 129
Cdd:PRK09665  90 DND-VAVSLVIALIVENPQQQLKLLRCLFGKLQQPDIV 126
nitro_reg_IIA TIGR01419
PTS IIA-like nitrogen-regulatory protein PtsN; This model describes a full-length protein of ...
 17-140 3.66e-08

PTS IIA-like nitrogen-regulatory protein PtsN; This model describes a full-length protein of about 160 residues closely related to the fructose-specific phosphotransferase (PTS) system IIA component. It is a regulatory protein found only in species with a phosphoenolpyruvate-protein phosphotransferase (enzyme I of PTS systems) and an HPr-like phosphocarrier protein, but not all species have a IIC-like permease. Members of this family are found in Proteobacteria, Chlamydia, and the spirochete Treponema pallidum. [Signal transduction, PTS]


Pssm-ID: 162350 [Multi-domain]  Cd Length: 145  Bit Score: 49.33  E-value: 3.66e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513   17 QSAIRFAGEALLEVNNIKSDYIQACID----REVDFPTGLslasGQGVAMPHGNSDFVTEDSVSVVRLSKPVAFGLMEDK 92
Cdd:TIGR01419  18 GSKKRLLEIISLLAARELSLPEQDVFEcllaREKLGSTGV----GNGIAIPHGRLSGLKQPVGVFIRLDAPVDFDALDGK 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 502727513   93 nqkvDVTLVFNLAL--SSGKQHIAVLRKVIALFQDDVFIKKCQKNSVEEV 140
Cdd:TIGR01419  94 ----PVDLLFALLVpeNATAEHLEALSRIARKLSDKTICRRLRAASAEEI 139
PRK10372 PRK10372
PTS ascorbate transporter subunit IIA;
15-126 1.26e-07

PTS ascorbate transporter subunit IIA;


Pssm-ID: 182417 [Multi-domain]  Cd Length: 154  Bit Score: 48.05  E-value: 1.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  15 DYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLSLASgqGVAMPHGN-SDFVTEDSVSVVRLSKPVAFGlmEDKN 93
Cdd:PRK10372  21 TWQEAVKIGVDLLVAADVVEPRYYQAILDGVEQFGPYFVIAP--GLAMPHGRpEEGVKKTGFALVTLKKPLEFN--HEDN 96

                         90       100       110
                 ....*....|....*....|....*....|...
gi 502727513  94 QKVDVTLVFNLALSSGKQHIAVlRKVIALFQDD 126
Cdd:PRK10372  97 DPVDILITMAAVDANTHQEVGI-MQIVNLFEDE 128
cmtB PRK09854
PTS mannitol transporter subunit IIA;
15-147 1.83e-06

PTS mannitol transporter subunit IIA;


Pssm-ID: 182114 [Multi-domain]  Cd Length: 147  Bit Score: 44.98  E-value: 1.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  15 DYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLSLASgqGVAMPHGNSDF-VTEDSVSVVRLSKPVAFGLMEDKn 93
Cdd:PRK09854  20 DWQEAIDFSMVSLLDKNYISENYIQAIKDSTINNGPYYILAP--GVAMPHARPECgALKTGMSLTLLEQGVYFPGNDEP- 96

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 502727513  94 qkvdVTLVFNLALSSGKQHIAVLRKVIALFQDDVFIKKCQKNSVEEVASDIKAK 147
Cdd:PRK09854  97 ----IKLLIGLSAADADSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISR 146
PRK13779 PRK13779
bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional
 13-126 8.72e-05

bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional


Pssm-ID: 237502 [Multi-domain]  Cd Length: 503  Bit Score: 41.40  E-value: 8.72e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  13 VNDYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLslasGQGVAMPHGNSD---FVTEDSVSVVRLSKPVAFGlm 89
Cdd:PRK13779  15 AINKQQAIEMAAAALEQAGNVENGYLQGMLARELQTSTFL----GNGIAIPHGTLDtrhMVKNTGVQIFQFPQGIEWG-- 88

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 502727513  90 eDKNQkvdVTLVFNLALSSgKQHIAVLRKVIALFQDD 126
Cdd:PRK13779  89 -EGNI---AYVVIGIAARS-DEHLSLLRQLTHVLSDE 120
PRK11109 PRK11109
fused PTS fructose transporter subunit IIA/HPr protein;
11-126 7.18e-04

fused PTS fructose transporter subunit IIA/HPr protein;


Pssm-ID: 236849 [Multi-domain]  Cd Length: 375  Bit Score: 38.39  E-value: 7.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502727513  11 ETVNDYQSAIRFAGEALLEVNNIKSDYIQACIDREVDFPTGLslasGQGVAMPHGNSD---FVTEDSVSVVRLSKPVAFG 87
Cdd:PRK11109  13 QQAGNKEEAIRQVAAALTQAGNVAEGYVDGMLAREQQTSTFL----GNGIAIPHGTTDtrdLVLKTGVQVFQFPQGVTWG 88

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 502727513  88 lmedKNQKVDVtlVFNLALSSgKQHIAVLRKVIALFQDD 126
Cdd:PRK11109  89 ----DGQTAYV--AIGIAAKS-DEHLGLLRQLTHVLSDD 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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