|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
309-524 |
1.28e-129 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
:
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 378.83 E-value: 1.28e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 309 GHKAAQARDGAALSRFLHWIATEAPKGG-VDELGAAAKLEAFRKETGLLEDLSFDTISGAGPNGAVVHYRVEERTNRPIE 387
Cdd:cd01085 1 GMRAAHIRDGVALVEFLAWLEQEVPKGEtITELSAADKLEEFRRQQKGYVGLSFDTISGFGPNGAIVHYSPTEESNRKIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 388 TGSFYLVDSGGQYRDGTTDVTRTIAIGTPSEEMKRRFTLVLKGHIALGRAQFPKGTRGGQLDVLARQFLWAEGLDYAHGT 467
Cdd:cd01085 81 PDGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGT 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 502803828 468 GHGVGSFLSVHEGPQRIAtFGGGDEPLQPGMILSNEPGYYKTGEYGIRIENLVLVEP 524
Cdd:cd01085 161 GHGVGSFLNVHEGPQSIS-PAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVE 216
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
148-306 |
2.39e-61 |
|
Creatinase/Prolidase N-terminal domain;
:
Pssm-ID: 465053 Cd Length: 159 Bit Score: 200.03 E-value: 2.39e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 148 DRPAPSDAKLVVHEDRYAGQSAAEKRQAMADWLVAKHADAAVLSALDSLAWTFNIRGKDVERTPVALAYAIVHADaTADL 227
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALKEKGADALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDD-EATL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 228 YVAPEKIDEAVVQHL-GNAVRVHDRADFAGALADFA-GKTVVADPERAVAAIFEALeAGGANILALRDPAVLPKAVKNPV 305
Cdd:pfam16189 80 FVDPEKLSDEVRAHLeENGVEIRPYDDIYEDLAALAaGKKVLLDPSRTSYALYSAL-PAGAKVVEAPSPITLMKAVKNET 158
|
.
gi 502803828 306 E 306
Cdd:pfam16189 159 E 159
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
533-593 |
1.43e-27 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
:
Pssm-ID: 465052 Cd Length: 63 Bit Score: 105.18 E-value: 1.43e-27
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 502803828 533 EMLGFETLTFAPIDRNAIATEMLTGEERAWLDAYHARVLEIVGPQL--EGGALDWLKAACAPL 593
Cdd:pfam16188 1 PFLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLeeEEDALEWLKRATRPI 63
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
7-138 |
4.83e-13 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
:
Pssm-ID: 460159 Cd Length: 128 Bit Score: 66.17 E-value: 4.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 7 RLKALRAQLVRVALDGFVVpltdehMSEYvgayaqRLAWLTGFQGSAGSAVVLPEEAAIFV--DGRYTLQVREQVDGAHW 84
Cdd:pfam01321 1 RLEKLRKLMEEKGLDAALV------TSPE------NLRYLTGFTGSRGLLLLVTADGALLLvdALEYERAAAESAPDFDV 68
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 502803828 85 qYESVPQTSVAAWLGEHVPAGGRIGYDPWLHTRAWVKAAGEALAerGAELVAVD 138
Cdd:pfam01321 69 -VPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEALP--GAELVDVS 119
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
309-524 |
1.28e-129 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 378.83 E-value: 1.28e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 309 GHKAAQARDGAALSRFLHWIATEAPKGG-VDELGAAAKLEAFRKETGLLEDLSFDTISGAGPNGAVVHYRVEERTNRPIE 387
Cdd:cd01085 1 GMRAAHIRDGVALVEFLAWLEQEVPKGEtITELSAADKLEEFRRQQKGYVGLSFDTISGFGPNGAIVHYSPTEESNRKIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 388 TGSFYLVDSGGQYRDGTTDVTRTIAIGTPSEEMKRRFTLVLKGHIALGRAQFPKGTRGGQLDVLARQFLWAEGLDYAHGT 467
Cdd:cd01085 81 PDGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGT 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 502803828 468 GHGVGSFLSVHEGPQRIAtFGGGDEPLQPGMILSNEPGYYKTGEYGIRIENLVLVEP 524
Cdd:cd01085 161 GHGVGSFLNVHEGPQSIS-PAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVE 216
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
174-546 |
6.50e-80 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 253.97 E-value: 6.50e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 174 QAMADWLVAKHADAAVLSALDSLAWTFNIRGkdverTPVALAYAIVHADATADLYVAPEKIDEAVVqhlgnavrvhdrad 253
Cdd:COG0006 1 ARLRALMAEAGLDALLLTDPSNFAYLTGFRG-----SPERLAALLVTADGEPVLFVDELEAERELV-------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 254 fagaladfagktvvadperAVAAIFEALeagganilalrdpavlpKAVKNPVEIAGHKAAQARDGAALSRFLHWIateap 333
Cdd:COG0006 62 -------------------DASDLLEEL-----------------RAIKSPEEIELMRKAARIADAAHEAALAAL----- 100
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 334 KGGVDELGAAAKLEAFRKETGLlEDLSFDTISGAGPNGAVVHYRveeRTNRPIETGSFYLVDSGGQYRDGTTDVTRTIAI 413
Cdd:COG0006 101 RPGVTEREVAAELEAAMRRRGA-EGPSFDTIVASGENAAIPHYT---PTDRPLKPGDLVLIDAGAEYDGYTSDITRTVAV 176
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 414 GTPSEEMKRRFTLVLKGHIAlGRAQFPKGTRGGQLDVLARQFLWAEGL--DYAHGTGHGVGsfLSVHEGPQrIATfgGGD 491
Cdd:COG0006 177 GEPSDEQREIYEAVLEAQEA-AIAALKPGVTGGEVDAAARDVLAEAGYgeYFPHGTGHGVG--LDVHEGPQ-ISP--GND 250
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 502803828 492 EPLQPGMILSNEPGYYKTGEYGIRIENLVLVEPRdvpgaeremlGFETLTFAPID 546
Cdd:COG0006 251 RPLEPGMVFTIEPGIYIPGIGGVRIEDTVLVTED----------GAEVLTRLPRE 295
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
148-306 |
2.39e-61 |
|
Creatinase/Prolidase N-terminal domain;
Pssm-ID: 465053 Cd Length: 159 Bit Score: 200.03 E-value: 2.39e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 148 DRPAPSDAKLVVHEDRYAGQSAAEKRQAMADWLVAKHADAAVLSALDSLAWTFNIRGKDVERTPVALAYAIVHADaTADL 227
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALKEKGADALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDD-EATL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 228 YVAPEKIDEAVVQHL-GNAVRVHDRADFAGALADFA-GKTVVADPERAVAAIFEALeAGGANILALRDPAVLPKAVKNPV 305
Cdd:pfam16189 80 FVDPEKLSDEVRAHLeENGVEIRPYDDIYEDLAALAaGKKVLLDPSRTSYALYSAL-PAGAKVVEAPSPITLMKAVKNET 158
|
.
gi 502803828 306 E 306
Cdd:pfam16189 159 E 159
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
308-522 |
3.79e-58 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 193.61 E-value: 3.79e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 308 AGHKAAQARDGAALSRFLHWIateapKGGVDELGAAAKLEAFRKETGLLEDLSFDTISGAGPNGAVVHYRveeRTNRPIE 387
Cdd:pfam00557 1 ELMRKAARIAAAALEAALAAI-----RPGVTERELAAELEAARLRRGGARGPAFPPIVASGPNAAIPHYI---PNDRVLK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 388 TGSFYLVDSGGQYRDG-TTDVTRTIAIGTPSEEMKRRFTLVLKGHIALGRAQFPkGTRGGQLDVLARQFLWAEGLD--YA 464
Cdd:pfam00557 73 PGDLVLIDVGAEYDGGyCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKP-GVTGGDVDAAAREVLEEAGLGeyFP 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 502803828 465 HGTGHGVGsfLSVHEGPQRIatFGGGDEPLQPGMILSNEPGYYK-TGEYGIRIENLVLV 522
Cdd:pfam00557 152 HGLGHGIG--LEVHEGPYIS--RGGDDRVLEPGMVFTIEPGIYFiPGWGGVRIEDTVLV 206
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
533-593 |
1.43e-27 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
Pssm-ID: 465052 Cd Length: 63 Bit Score: 105.18 E-value: 1.43e-27
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 502803828 533 EMLGFETLTFAPIDRNAIATEMLTGEERAWLDAYHARVLEIVGPQL--EGGALDWLKAACAPL 593
Cdd:pfam16188 1 PFLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLeeEEDALEWLKRATRPI 63
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
299-531 |
4.07e-22 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 98.09 E-value: 4.07e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 299 KAVKNPVEIAG-HKAAQARDGAA--LSRFLhwiateapKGGVDELGAAAKLEAFRKETGLlEDLSFDTISGAGPNGAVVH 375
Cdd:PRK09795 125 RQIKTPEEVEKiRLACGIADRGAehIRRFI--------QAGMSEREIAAELEWFMRQQGA-EKASFDTIVASGWRGALPH 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 376 YRVEERTnrpIETGSFYLVDSGGQYRDGTTDVTRTIAI---GTPSEE--MKRRFTLVLKGHIALGRAQFPkGTRGGQLDV 450
Cdd:PRK09795 196 GKASDKI---VAAGEFVTLDFGALYQGYCSDMTRTLLVngeGVSAEShpLFNVYQIVLQAQLAAISAIRP-GVRCQQVDD 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 451 LARQFLWAEGLD--YAHGTGHGVGsfLSVHEGPQriatFGGGDEP-LQPGMILSNEPGYYKTGEYGIRIENLVLVEPRdv 527
Cdd:PRK09795 272 AARRVITEAGYGdyFGHNTGHAIG--IEVHEDPR----FSPRDTTtLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQ-- 343
|
....
gi 502803828 528 pGAE 531
Cdd:PRK09795 344 -GAE 346
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
7-138 |
4.83e-13 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
Pssm-ID: 460159 Cd Length: 128 Bit Score: 66.17 E-value: 4.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 7 RLKALRAQLVRVALDGFVVpltdehMSEYvgayaqRLAWLTGFQGSAGSAVVLPEEAAIFV--DGRYTLQVREQVDGAHW 84
Cdd:pfam01321 1 RLEKLRKLMEEKGLDAALV------TSPE------NLRYLTGFTGSRGLLLLVTADGALLLvdALEYERAAAESAPDFDV 68
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 502803828 85 qYESVPQTSVAAWLGEHVPAGGRIGYDPWLHTRAWVKAAGEALAerGAELVAVD 138
Cdd:pfam01321 69 -VPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEALP--GAELVDVS 119
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
309-524 |
1.28e-129 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 378.83 E-value: 1.28e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 309 GHKAAQARDGAALSRFLHWIATEAPKGG-VDELGAAAKLEAFRKETGLLEDLSFDTISGAGPNGAVVHYRVEERTNRPIE 387
Cdd:cd01085 1 GMRAAHIRDGVALVEFLAWLEQEVPKGEtITELSAADKLEEFRRQQKGYVGLSFDTISGFGPNGAIVHYSPTEESNRKIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 388 TGSFYLVDSGGQYRDGTTDVTRTIAIGTPSEEMKRRFTLVLKGHIALGRAQFPKGTRGGQLDVLARQFLWAEGLDYAHGT 467
Cdd:cd01085 81 PDGLYLIDSGGQYLDGTTDITRTVHLGEPTAEQKRDYTLVLKGHIALARAKFPKGTTGSQLDALARQPLWKAGLDYGHGT 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 502803828 468 GHGVGSFLSVHEGPQRIAtFGGGDEPLQPGMILSNEPGYYKTGEYGIRIENLVLVEP 524
Cdd:cd01085 161 GHGVGSFLNVHEGPQSIS-PAPNNVPLKAGMILSNEPGYYKEGKYGIRIENLVLVVE 216
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
174-546 |
6.50e-80 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 253.97 E-value: 6.50e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 174 QAMADWLVAKHADAAVLSALDSLAWTFNIRGkdverTPVALAYAIVHADATADLYVAPEKIDEAVVqhlgnavrvhdrad 253
Cdd:COG0006 1 ARLRALMAEAGLDALLLTDPSNFAYLTGFRG-----SPERLAALLVTADGEPVLFVDELEAERELV-------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 254 fagaladfagktvvadperAVAAIFEALeagganilalrdpavlpKAVKNPVEIAGHKAAQARDGAALSRFLHWIateap 333
Cdd:COG0006 62 -------------------DASDLLEEL-----------------RAIKSPEEIELMRKAARIADAAHEAALAAL----- 100
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 334 KGGVDELGAAAKLEAFRKETGLlEDLSFDTISGAGPNGAVVHYRveeRTNRPIETGSFYLVDSGGQYRDGTTDVTRTIAI 413
Cdd:COG0006 101 RPGVTEREVAAELEAAMRRRGA-EGPSFDTIVASGENAAIPHYT---PTDRPLKPGDLVLIDAGAEYDGYTSDITRTVAV 176
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 414 GTPSEEMKRRFTLVLKGHIAlGRAQFPKGTRGGQLDVLARQFLWAEGL--DYAHGTGHGVGsfLSVHEGPQrIATfgGGD 491
Cdd:COG0006 177 GEPSDEQREIYEAVLEAQEA-AIAALKPGVTGGEVDAAARDVLAEAGYgeYFPHGTGHGVG--LDVHEGPQ-ISP--GND 250
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 502803828 492 EPLQPGMILSNEPGYYKTGEYGIRIENLVLVEPRdvpgaeremlGFETLTFAPID 546
Cdd:COG0006 251 RPLEPGMVFTIEPGIYIPGIGGVRIEDTVLVTED----------GAEVLTRLPRE 295
|
|
| Creatinase_N_2 |
pfam16189 |
Creatinase/Prolidase N-terminal domain; |
148-306 |
2.39e-61 |
|
Creatinase/Prolidase N-terminal domain;
Pssm-ID: 465053 Cd Length: 159 Bit Score: 200.03 E-value: 2.39e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 148 DRPAPSDAKLVVHEDRYAGQSAAEKRQAMADWLVAKHADAAVLSALDSLAWTFNIRGKDVERTPVALAYAIVHADaTADL 227
Cdd:pfam16189 1 DRPALPANPVFVLPLKYAGESAAEKLARLREALKEKGADALVLSALDEIAWLLNLRGSDVPYNPVFLSYALVTDD-EATL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 228 YVAPEKIDEAVVQHL-GNAVRVHDRADFAGALADFA-GKTVVADPERAVAAIFEALeAGGANILALRDPAVLPKAVKNPV 305
Cdd:pfam16189 80 FVDPEKLSDEVRAHLeENGVEIRPYDDIYEDLAALAaGKKVLLDPSRTSYALYSAL-PAGAKVVEAPSPITLMKAVKNET 158
|
.
gi 502803828 306 E 306
Cdd:pfam16189 159 E 159
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
308-522 |
3.79e-58 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 193.61 E-value: 3.79e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 308 AGHKAAQARDGAALSRFLHWIateapKGGVDELGAAAKLEAFRKETGLLEDLSFDTISGAGPNGAVVHYRveeRTNRPIE 387
Cdd:pfam00557 1 ELMRKAARIAAAALEAALAAI-----RPGVTERELAAELEAARLRRGGARGPAFPPIVASGPNAAIPHYI---PNDRVLK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 388 TGSFYLVDSGGQYRDG-TTDVTRTIAIGTPSEEMKRRFTLVLKGHIALGRAQFPkGTRGGQLDVLARQFLWAEGLD--YA 464
Cdd:pfam00557 73 PGDLVLIDVGAEYDGGyCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKP-GVTGGDVDAAAREVLEEAGLGeyFP 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 502803828 465 HGTGHGVGsfLSVHEGPQRIatFGGGDEPLQPGMILSNEPGYYK-TGEYGIRIENLVLV 522
Cdd:pfam00557 152 HGLGHGIG--LEVHEGPYIS--RGGDDRVLEPGMVFTIEPGIYFiPGWGGVRIEDTVLV 206
|
|
| APP-like |
cd01092 |
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse ... |
316-522 |
5.68e-44 |
|
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline.
Pssm-ID: 238525 [Multi-domain] Cd Length: 208 Bit Score: 155.74 E-value: 5.68e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 316 RDGAALSRFLHWIATEAPKGGVDELGAAAKLEAFRKETGLlEDLSFDTISGAGPNGAVVHYRVeerTNRPIETGSFYLVD 395
Cdd:cd01092 5 RKAARIADKAFEELLEFIKPGMTEREVAAELEYFMRKLGA-EGPSFDTIVASGPNSALPHGVP---SDRKIEEGDLVLID 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 396 SGGQYRDGTTDVTRTIAIGTPSEEMKRRFTLVLKGHIAlGRAQFPKGTRGGQLDVLARQFLWAEGL-DY-AHGTGHGVGs 473
Cdd:cd01092 81 FGAIYDGYCSDITRTVAVGEPSDELKEIYEIVLEAQQA-AIKAVKPGVTAKEVDKAARDVIEEAGYgEYfIHRTGHGVG- 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 502803828 474 fLSVHEGPqRIAtfGGGDEPLQPGMILSNEPGYYKTGEYGIRIENLVLV 522
Cdd:cd01092 159 -LEVHEAP-YIS--PGSDDVLEEGMVFTIEPGIYIPGKGGVRIEDDVLV 203
|
|
| Peptidase_M24_C |
pfam16188 |
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of ... |
533-593 |
1.43e-27 |
|
C-terminal region of peptidase_M24; This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.
Pssm-ID: 465052 Cd Length: 63 Bit Score: 105.18 E-value: 1.43e-27
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 502803828 533 EMLGFETLTFAPIDRNAIATEMLTGEERAWLDAYHARVLEIVGPQL--EGGALDWLKAACAPL 593
Cdd:pfam16188 1 PFLGFETLTLVPIDRKLIDVSLLTEEEIEWLNAYHARVREKLSPLLeeEEDALEWLKRATRPI 63
|
|
| APP_MetAP |
cd01066 |
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as ... |
307-525 |
1.36e-26 |
|
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity compared to other metallo-aminopeptidases, suggesting they play roles in regulation of biological processes rather than general protein degradation.
Pssm-ID: 238514 [Multi-domain] Cd Length: 207 Bit Score: 107.54 E-value: 1.36e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 307 IAGHKAAQARDGAALSRFLHWIateapKGGVDELGAAAKLEAFRKETGLLEdlSFDTISGAGPNGAVVHYRVeerTNRPI 386
Cdd:cd01066 1 IARLRKAAEIAEAAMAAAAEAI-----RPGVTEAEVAAAIEQALRAAGGYP--AGPTIVGSGARTALPHYRP---DDRRL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 387 ETGSFYLVDSGGQYRDGTTDVTRTIAIGTPSEEMKRRFTLVLKGHIALGRAQFPkGTRGGQLDVLARQFLWAEGL--DYA 464
Cdd:cd01066 71 QEGDLVLVDLGGVYDGYHADLTRTFVIGEPSDEQRELYEAVREAQEAALAALRP-GVTAEEVDAAAREVLEEHGLgpNFG 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 502803828 465 HGTGHGVGsfLSVHEGPQriaTFGGGDEPLQPGMILSNEPGYYKTGEYGIRIENLVLVEPR 525
Cdd:cd01066 150 HRTGHGIG--LEIHEPPV---LKAGDDTVLEPGMVFAVEPGLYLPGGGGVRIEDTVLVTED 205
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
299-531 |
4.07e-22 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 98.09 E-value: 4.07e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 299 KAVKNPVEIAG-HKAAQARDGAA--LSRFLhwiateapKGGVDELGAAAKLEAFRKETGLlEDLSFDTISGAGPNGAVVH 375
Cdd:PRK09795 125 RQIKTPEEVEKiRLACGIADRGAehIRRFI--------QAGMSEREIAAELEWFMRQQGA-EKASFDTIVASGWRGALPH 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 376 YRVEERTnrpIETGSFYLVDSGGQYRDGTTDVTRTIAI---GTPSEE--MKRRFTLVLKGHIALGRAQFPkGTRGGQLDV 450
Cdd:PRK09795 196 GKASDKI---VAAGEFVTLDFGALYQGYCSDMTRTLLVngeGVSAEShpLFNVYQIVLQAQLAAISAIRP-GVRCQQVDD 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 451 LARQFLWAEGLD--YAHGTGHGVGsfLSVHEGPQriatFGGGDEP-LQPGMILSNEPGYYKTGEYGIRIENLVLVEPRdv 527
Cdd:PRK09795 272 AARRVITEAGYGdyFGHNTGHAIG--IEVHEDPR----FSPRDTTtLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQ-- 343
|
....
gi 502803828 528 pGAE 531
Cdd:PRK09795 344 -GAE 346
|
|
| Prolidase |
cd01087 |
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline ... |
334-522 |
1.21e-18 |
|
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.
Pssm-ID: 238520 [Multi-domain] Cd Length: 243 Bit Score: 85.70 E-value: 1.21e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 334 KGGVDELGAAAKLE-AFRKETGlleDLSFDTISGAGPNGAVVHYRveeRTNRPIETGSFYLVDSGGQYRDGTTDVTRTIA 412
Cdd:cd01087 23 RPGMSEYELEAEFEyEFRSRGA---RLAYSYIVAAGSNAAILHYV---HNDQPLKDGDLVLIDAGAEYGGYASDITRTFP 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 413 I-GTPSEEMKRRFTLVLKGHIALGRAQFPkGTRGGQLDVLARQFLwAEGLD---------------------YAHGTGHG 470
Cdd:cd01087 97 VnGKFTDEQRELYEAVLAAQKAAIAACKP-GVSYEDIHLLAHRVL-AEGLKelgilkgdvdeivesgayakfFPHGLGHY 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 502803828 471 VGsfLSVHEGPQRIAtFGGGDEPLQPGMILSNEPGYY------KTGEY----GIRIENLVLV 522
Cdd:cd01087 175 LG--LDVHDVGGYLR-YLRRARPLEPGMVITIEPGIYfipdllDVPEYfrggGIRIEDDVLV 233
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
7-138 |
4.83e-13 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
Pssm-ID: 460159 Cd Length: 128 Bit Score: 66.17 E-value: 4.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 7 RLKALRAQLVRVALDGFVVpltdehMSEYvgayaqRLAWLTGFQGSAGSAVVLPEEAAIFV--DGRYTLQVREQVDGAHW 84
Cdd:pfam01321 1 RLEKLRKLMEEKGLDAALV------TSPE------NLRYLTGFTGSRGLLLLVTADGALLLvdALEYERAAAESAPDFDV 68
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 502803828 85 qYESVPQTSVAAWLGEHVPAGGRIGYDPWLHTRAWVKAAGEALAerGAELVAVD 138
Cdd:pfam01321 69 -VPYRDYEALADLLKELGAGGKRVGFEADALTVAFYEALKEALP--GAELVDVS 119
|
|
| PRK10879 |
PRK10879 |
proline aminopeptidase P II; Provisional |
360-522 |
1.96e-09 |
|
proline aminopeptidase P II; Provisional
Pssm-ID: 182804 [Multi-domain] Cd Length: 438 Bit Score: 60.12 E-value: 1.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 360 SFDTISGAGPNGAVVHYRVEERTNRpieTGSFYLVDSGGQYRDGTTDVTRTIAI-GTPSEEMKRRFTLVLKGhIALGRAQ 438
Cdd:PRK10879 226 SYNTIVGSGENGCILHYTENESEMR---DGDLVLIDAGCEYKGYAGDITRTFPVnGKFTPAQREIYDIVLES-LETSLRL 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 439 FPKGTR----------------------GGQLDVLA-----RQFlwaegldYAHGTGHGVGsfLSVHE----GPQRiatf 487
Cdd:PRK10879 302 YRPGTSirevtgevvrimvsglvklgilKGDVDQLIaenahRPF-------FMHGLSHWLG--LDVHDvgvyGQDR---- 368
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 502803828 488 gggDEPLQPGMILSNEPGYYKT------GEY---GIRIENLVLV 522
Cdd:PRK10879 369 ---SRILEPGMVLTVEPGLYIApdadvpEQYrgiGIRIEDDIVI 409
|
|
| PRK14576 |
PRK14576 |
putative endopeptidase; Provisional |
385-522 |
1.27e-04 |
|
putative endopeptidase; Provisional
Pssm-ID: 173040 [Multi-domain] Cd Length: 405 Bit Score: 44.62 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 385 PIETGSFYLVDSGGQYRDGTTDVTRTIAIGTPSEEMKRRFTLVLKGHIALGRAQFP----KGTRGGQLDVLARQflwaeG 460
Cdd:PRK14576 251 PAKVGDLIKFDCGIDVAGYGADLARTFVLGEPDKLTQQIYDTIRTGHEHMLSMVAPgvklKAVFDSTMAVIKTS-----G 325
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502803828 461 LDYAH--GTGHGVGSFLSVHEGP--QRIATfgggdEPLQPGMILSNEPGYYKTGEYGIRIENLVLV 522
Cdd:PRK14576 326 LPHYNrgHLGHGDGVFLGLEEVPfvSTQAT-----ETFCPGMVLSLETPYYGIGVGSIMLEDMILI 386
|
|
| PRK15173 |
PRK15173 |
peptidase; Provisional |
388-522 |
1.86e-04 |
|
peptidase; Provisional
Pssm-ID: 185095 [Multi-domain] Cd Length: 323 Bit Score: 43.94 E-value: 1.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 388 TGSFYLVDSGGQYRDGTTDVTRTIAIGTPSEEMKRRFTLVLKGHIALGRAQFPkGTRGGQLDVLARQFLWAEGL-DYAHG 466
Cdd:PRK15173 172 SGDLIKFDCGVDVDGYGADIARTFVVGEPPEITRKIYQTIRTGHEHMLSMVAP-GVKMKDVFDSTMEVIKKSGLpNYNRG 250
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 502803828 467 -TGHGVGSFLSVHEGPqRIATFGggDEPLQPGMILSNEPGYYKTGEYGIRIENLVLV 522
Cdd:PRK15173 251 hLGHGNGVFLGLEESP-FVSTHA--TESFTSGMVLSLETPYYGYNLGSIMIEDMILI 304
|
|
| PRK14575 |
PRK14575 |
putative peptidase; Provisional |
388-522 |
2.93e-04 |
|
putative peptidase; Provisional
Pssm-ID: 173039 [Multi-domain] Cd Length: 406 Bit Score: 43.54 E-value: 2.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 388 TGSFYLVDSGGQYRDGTTDVTRTIAIGTPSEEMKRRFTLVLKGHIALGRAQFPkGTRGGQLDVLARQFLWAEGL-DYAHG 466
Cdd:PRK14575 255 SGDLIKFDCGVDVDGYGADIARTFVVGEPPEITRKIYQTIRTGHEHMLSMVAP-GVKMKDVFDSTMEVIKKSGLpNYNRG 333
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 502803828 467 -TGHGVGSFLSVHEGPqRIATFGggDEPLQPGMILSNEPGYYKTGEYGIRIENLVLV 522
Cdd:PRK14575 334 hLGHGNGVFLGLEESP-FVSTHA--TESFTSGMVLSLETPYYGYNLGSIMIEDMILI 387
|
|
| PRK05716 |
PRK05716 |
methionine aminopeptidase; Validated |
406-504 |
1.15e-03 |
|
methionine aminopeptidase; Validated
Pssm-ID: 235576 [Multi-domain] Cd Length: 252 Bit Score: 40.89 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502803828 406 DVTRTIAIGTPSEEMKRrftLVLKGHIAL--GRAQFPKGTRGGQLDVLARQFLWAEGL----DYahgTGHGVGSflSVHE 479
Cdd:PRK05716 106 DTSRTFGVGEISPEDKR---LCEVTKEALylGIAAVKPGARLGDIGHAIQKYAEAEGFsvvrEY---CGHGIGR--KFHE 177
|
90 100
....*....|....*....|....*..
gi 502803828 480 GPQrIATFG--GGDEPLQPGMILSNEP 504
Cdd:PRK05716 178 EPQ-IPHYGapGDGPVLKEGMVFTIEP 203
|
|
| |
