|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11302 |
PRK11302 |
DNA-binding transcriptional regulator HexR; Provisional |
1-284 |
0e+00 |
|
DNA-binding transcriptional regulator HexR; Provisional
Pssm-ID: 183082 [Multi-domain] Cd Length: 284 Bit Score: 594.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 1 MNTLEKVQKSLTHFSKSERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPY 80
Cdd:PRK11302 1 MNMLEKIQSRLEHLSKSERKVAEVILASPQTAIHSSIATLAKMANVSEPTVNRFCRSLDTKGFPDFKLHLAQSLANGTPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 81 VSRHVEEDDTPESYTTKIFESSMASLDTARQSIDTTAINKAVDILTQAKKISFFGLGASASVAHDAQNKFFRFNVPVICF 160
Cdd:PRK11302 81 VNRNVEEDDSVEAYTGKIFESAMASLDHARQSLDPSAINRAVDLLTQAKKISFFGLGASAAVAHDAQNKFFRFNVPVVYF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 161 DDVLMQRMSCINSGEGDVIVLISHTGRTKSMIDIARIARENGAAVIGITTLDSPLSIECTLPITMEVPEDTDMYLPMASR 240
Cdd:PRK11302 161 DDIVMQRMSCMNSSDGDVVVLISHTGRTKSLVELAQLARENGATVIAITSAGSPLAREATLALTLDVPEDTDIYMPMVSR 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 502816617 241 LAQLVVIDVLATGFTLRRGPRFRESLKRVKEVLKESRIDKDSIM 284
Cdd:PRK11302 241 IAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKESRFDKDLLN 284
|
|
| RpiR |
COG1737 |
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains ... |
1-278 |
4.09e-95 |
|
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains [Transcription];
Pssm-ID: 441343 [Multi-domain] Cd Length: 286 Bit Score: 281.82 E-value: 4.09e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 1 MNTLEKVQKSLTHFSKSERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPY 80
Cdd:COG1737 5 MSLLERIRARYPSLSPSERRIADYILDNPEEVAFMSIAELAEAAGVSEATVVRFCRKLGFSGFPELKLALAQELAEGLSS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 81 VSRH--VEEDDTPESYTTKIFESSMASLDTARQSIDTTAINKAVDILTQAKKISFFGLGASASVAHDAQNKFFRFNVPVI 158
Cdd:COG1737 85 YERLrrLSPDDSLEDILAKVLEAEIANLEETLELLDEEALERAVDLLAKARRIYIFGVGASAPVAEDLAYKLLRLGKNVV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 159 CFD-DVLMQRMSCINSGEGDVIVLISHTGRTKSMIDIARIARENGAAVIGIT-TLDSPLSIECTLPITMEVPEDTDMYLP 236
Cdd:COG1737 165 LLDgDGHLQAESAALLGPGDVVIAISFSGYTRETLEAARLAKERGAKVIAITdSPLSPLAKLADVVLYVPSEEPTLRSSA 244
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 502816617 237 MASRLAQLVVIDVLATGFTLRRGPRFRESLKRVKEVLKESRI 278
Cdd:COG1737 245 FSSRVAQLALIDALAAAVAQRDGDKARERLERTEALLSELRE 286
|
|
| SIS_RpiR |
cd05013 |
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many ... |
117-253 |
3.76e-42 |
|
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate isomerases that catalyze the reversible reactions of ribose 5-phosphate into ribulose 5-phosphate.
Pssm-ID: 240144 [Multi-domain] Cd Length: 139 Bit Score: 141.60 E-value: 3.76e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 117 AINKAVDILTQAKKISFFGLGASASVAHDAQNKFFRFNVPVICFDDVLMQRMSCINSGEGDVIVLISHTGRTKSMIDIAR 196
Cdd:cd05013 2 ALEKAVDLLAKARRIYIFGVGSSGLVAEYLAYKLLRLGKPVVLLSDPHLQLMSAANLTPGDVVIAISFSGETKETVEAAE 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 502816617 197 IARENGAAVIGITTL-DSPLSIECTLPITMEVPEDTDMYLPMASRLAQLVVIDVLATG 253
Cdd:cd05013 82 IAKERGAKVIAITDSaNSPLAKLADIVLLVSSEEGDFRSSAFSSRIAQLALIDALFLA 139
|
|
| HTH_6 |
pfam01418 |
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best ... |
1-77 |
1.31e-30 |
|
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best characterized member of this family is Swiss:P39266. RpiR is a regulator of the expression of rpiB gene.
Pssm-ID: 334531 [Multi-domain] Cd Length: 77 Bit Score: 109.73 E-value: 1.31e-30
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 502816617 1 MNTLEKVQKSLTHFSKSERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANG 77
Cdd:pfam01418 1 MGLLEKIQSRYSKLTKSERKIADYILAHPDLAIHLSISAIAKAAGVSEATIVRFCQKLGFSGFPELKLALAGELANS 77
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11302 |
PRK11302 |
DNA-binding transcriptional regulator HexR; Provisional |
1-284 |
0e+00 |
|
DNA-binding transcriptional regulator HexR; Provisional
Pssm-ID: 183082 [Multi-domain] Cd Length: 284 Bit Score: 594.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 1 MNTLEKVQKSLTHFSKSERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPY 80
Cdd:PRK11302 1 MNMLEKIQSRLEHLSKSERKVAEVILASPQTAIHSSIATLAKMANVSEPTVNRFCRSLDTKGFPDFKLHLAQSLANGTPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 81 VSRHVEEDDTPESYTTKIFESSMASLDTARQSIDTTAINKAVDILTQAKKISFFGLGASASVAHDAQNKFFRFNVPVICF 160
Cdd:PRK11302 81 VNRNVEEDDSVEAYTGKIFESAMASLDHARQSLDPSAINRAVDLLTQAKKISFFGLGASAAVAHDAQNKFFRFNVPVVYF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 161 DDVLMQRMSCINSGEGDVIVLISHTGRTKSMIDIARIARENGAAVIGITTLDSPLSIECTLPITMEVPEDTDMYLPMASR 240
Cdd:PRK11302 161 DDIVMQRMSCMNSSDGDVVVLISHTGRTKSLVELAQLARENGATVIAITSAGSPLAREATLALTLDVPEDTDIYMPMVSR 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 502816617 241 LAQLVVIDVLATGFTLRRGPRFRESLKRVKEVLKESRIDKDSIM 284
Cdd:PRK11302 241 IAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKESRFDKDLLN 284
|
|
| RpiR |
COG1737 |
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains ... |
1-278 |
4.09e-95 |
|
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains [Transcription];
Pssm-ID: 441343 [Multi-domain] Cd Length: 286 Bit Score: 281.82 E-value: 4.09e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 1 MNTLEKVQKSLTHFSKSERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPY 80
Cdd:COG1737 5 MSLLERIRARYPSLSPSERRIADYILDNPEEVAFMSIAELAEAAGVSEATVVRFCRKLGFSGFPELKLALAQELAEGLSS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 81 VSRH--VEEDDTPESYTTKIFESSMASLDTARQSIDTTAINKAVDILTQAKKISFFGLGASASVAHDAQNKFFRFNVPVI 158
Cdd:COG1737 85 YERLrrLSPDDSLEDILAKVLEAEIANLEETLELLDEEALERAVDLLAKARRIYIFGVGASAPVAEDLAYKLLRLGKNVV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 159 CFD-DVLMQRMSCINSGEGDVIVLISHTGRTKSMIDIARIARENGAAVIGIT-TLDSPLSIECTLPITMEVPEDTDMYLP 236
Cdd:COG1737 165 LLDgDGHLQAESAALLGPGDVVIAISFSGYTRETLEAARLAKERGAKVIAITdSPLSPLAKLADVVLYVPSEEPTLRSSA 244
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 502816617 237 MASRLAQLVVIDVLATGFTLRRGPRFRESLKRVKEVLKESRI 278
Cdd:COG1737 245 FSSRVAQLALIDALAAAVAQRDGDKARERLERTEALLSELRE 286
|
|
| PRK14101 |
PRK14101 |
bifunctional transcriptional regulator/glucokinase; |
4-258 |
2.06e-65 |
|
bifunctional transcriptional regulator/glucokinase;
Pssm-ID: 184507 [Multi-domain] Cd Length: 638 Bit Score: 215.55 E-value: 2.06e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 4 LEKVQKSLTHFSKSERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPYVSR 83
Cdd:PRK14101 344 FERIRQMRDALTPAERRVADLALNHPRSIINDPIVDIARKADVSQPTVIRFCRSLGCQGLSDFKLKLATGLTGTIPMSHS 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 84 HVEEDDTPESYTTKIFESSMASLDTARQSIDTTAINKAVDILTQAKKISFFGLGASASVAHDAQNKFFRFNVPVICFDDV 163
Cdd:PRK14101 424 QVHLGDTATDFGAKVLDNTVSAILQLREHLNFEHVEQAIDILNNARRIEFYGLGNSNIVAQDAHYKFFRFGIPTIAYGDL 503
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 164 LMQRMSCINSGEGDVIVLISHTGRTKSMIDIARIARENGAAVIGITTLDSPLSIECTLPITMEVPEDTDMYLPMASRLAQ 243
Cdd:PRK14101 504 YMQAASAALLGKGDVIVAVSKSGRAPELLRVLDVAMQAGAKVIAITSSNTPLAKRATVALETDHIEMRESQLSMISRILH 583
|
250
....*....|....*
gi 502816617 244 LVVIDVLATGFTLRR 258
Cdd:PRK14101 584 LVMIDILAVGVAIRR 598
|
|
| PRK11337 |
PRK11337 |
MurR/RpiR family transcriptional regulator; |
18-250 |
1.53e-42 |
|
MurR/RpiR family transcriptional regulator;
Pssm-ID: 183089 [Multi-domain] Cd Length: 292 Bit Score: 147.21 E-value: 1.53e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 18 ERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSlaNGTPYVSRHVE--EDDTPESYT 95
Cdd:PRK11337 30 ESRVVEWLLKPGDLSEATALKDIAEALAVSEAMIVKVAKKLGFSGFRNLRSALEDY--FSQSEQVLHSElsFDDAPQDVV 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 96 TKIFESSMASLDTARQSIDTTAINKAVDILTQAKKISFFGLGASASVAHDAQNKFFRFNVPVICFDDVLMQRMSCINSGE 175
Cdd:PRK11337 108 NKVFNTSLQAIEETQSILDVDEFHRAARFFYQARQRDLYGAGGSAAIARDVQHKFLRIGVRCQAYDDAHIMLMSAALLQE 187
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 502816617 176 GDVIVLISHTGRTKSMIDIARIARENGAAVIGITTLD-SPLSIECTLPITMEVPEDTDMYLPMASRLAQLVVIDVL 250
Cdd:PRK11337 188 GDVVLVVSHSGRTSDVIEAVELAKKNGAKIICITNSYhSPIAKLADYVICSTAQGSPLLGENAAARIAQLNILDAF 263
|
|
| SIS_RpiR |
cd05013 |
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many ... |
117-253 |
3.76e-42 |
|
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate isomerases that catalyze the reversible reactions of ribose 5-phosphate into ribulose 5-phosphate.
Pssm-ID: 240144 [Multi-domain] Cd Length: 139 Bit Score: 141.60 E-value: 3.76e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 117 AINKAVDILTQAKKISFFGLGASASVAHDAQNKFFRFNVPVICFDDVLMQRMSCINSGEGDVIVLISHTGRTKSMIDIAR 196
Cdd:cd05013 2 ALEKAVDLLAKARRIYIFGVGSSGLVAEYLAYKLLRLGKPVVLLSDPHLQLMSAANLTPGDVVIAISFSGETKETVEAAE 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 502816617 197 IARENGAAVIGITTL-DSPLSIECTLPITMEVPEDTDMYLPMASRLAQLVVIDVLATG 253
Cdd:cd05013 82 IAKERGAKVIAITDSaNSPLAKLADIVLLVSSEEGDFRSSAFSSRIAQLALIDALFLA 139
|
|
| HTH_6 |
pfam01418 |
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best ... |
1-77 |
1.31e-30 |
|
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best characterized member of this family is Swiss:P39266. RpiR is a regulator of the expression of rpiB gene.
Pssm-ID: 334531 [Multi-domain] Cd Length: 77 Bit Score: 109.73 E-value: 1.31e-30
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 502816617 1 MNTLEKVQKSLTHFSKSERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANG 77
Cdd:pfam01418 1 MGLLEKIQSRYSKLTKSERKIADYILAHPDLAIHLSISAIAKAAGVSEATIVRFCQKLGFSGFPELKLALAGELANS 77
|
|
| PRK15482 |
PRK15482 |
HTH-type transcriptional regulator MurR; |
1-254 |
5.37e-24 |
|
HTH-type transcriptional regulator MurR;
Pssm-ID: 185379 [Multi-domain] Cd Length: 285 Bit Score: 98.23 E-value: 5.37e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 1 MNTLEKVQKSLTHFSKSERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLA----- 75
Cdd:PRK15482 1 MLYLTKIRNAESEFTENEQKIADFLRANVSELKSVSSRKMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSasrek 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 76 -NGTP-YVSRHVEEDDTPESYTTKIFESSMASLDTARQSIDTTAINKAVDILTQAKKISFFGLGASASVAHDAQNKFFRF 153
Cdd:PRK15482 81 tNATAlHLHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 154 NVPVICFDDVLMQRMSCINSGEGDVIVLISHTGRTKSMIDIARIARENGAAVIGITTL-DSPLSIECTLPITMEVPEDTD 232
Cdd:PRK15482 161 GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLaDSPLRRLAHFTLDTVSGETEW 240
|
250 260
....*....|....*....|..
gi 502816617 233 MYLPMASRLAQLVVIDVLATGF 254
Cdd:PRK15482 241 RSSSMSTRTAQNSVTDLLFVGL 262
|
|
| SIS |
pfam01380 |
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
124-252 |
2.12e-21 |
|
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars. Presumably the SIS domains bind to the end-product of the pathway.
Pssm-ID: 426230 [Multi-domain] Cd Length: 131 Bit Score: 87.35 E-value: 2.12e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 124 ILTQAKKISFFGLGASASVAHDAQNKFFRFNV-PVICFDDVLMQRMSCINSGEGDVIVLISHTGRTKSMIDIARIARENG 202
Cdd:pfam01380 1 LLAKAKRIFVIGRGTSYAIALELALKFEEIGYkVVEVELASELRHGVLALVDEDDLVIAISYSGETKDLLAAAELAKARG 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 502816617 203 AAVIGIT-TLDSPLSIECTLPITMEVPEDTdMYLPMASRLAQLVVIDVLAT 252
Cdd:pfam01380 81 AKIIAITdSPGSPLAREADHVLYINAGPET-GVASTKSITAQLAALDALAV 130
|
|
| SIS_PHI |
cd05005 |
Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) ... |
106-215 |
2.17e-10 |
|
Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with formadelhyde to become hexulose-6-phosphate, which is then isomerized to fructose-6-phosphate by PHI.
Pssm-ID: 240138 [Multi-domain] Cd Length: 179 Bit Score: 58.36 E-value: 2.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 106 LDTARQSIDTTAINKAVDILTQAKKISFFGLGASASVAhdaqnKFF--R-----FNVPVIcFDDVlmqrmsCINSGEGDV 178
Cdd:cd05005 11 IENVADKIDEEELDKLISAILNAKRIFVYGAGRSGLVA-----KAFamRlmhlgLNVYVV-GETT------TPAIGPGDL 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 502816617 179 IVLISHTGRTKSMIDIARIARENGAAVIGITT-LDSPL 215
Cdd:cd05005 79 LIAISGSGETSSVVNAAEKAKKAGAKVVLITSnPDSPL 116
|
|
| SIS_1 |
cd05710 |
A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar ... |
174-237 |
2.25e-09 |
|
A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240214 [Multi-domain] Cd Length: 120 Bit Score: 54.12 E-value: 2.25e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 502816617 174 GEGDVIVLISHTGRTKSMIDIARIARENGAAVIGITT-LDSPLSIECTLPITMEVPEDTDMYLPM 237
Cdd:cd05710 46 TEKSVVILASHSGNTKETVAAAKFAKEKGATVIGLTDdEDSPLAKLADYVIVYGFEIDAVEEKYL 110
|
|
| SIS_Kpsf |
cd05014 |
KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ... |
175-251 |
1.20e-08 |
|
KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose 5-phosphate to arabinose 5-phosphate. This is the second step in the CMP-Kdo biosynthesis pathway.
Pssm-ID: 240145 [Multi-domain] Cd Length: 128 Bit Score: 52.54 E-value: 1.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 175 EGDVIVLISHTGRTKSMIDIARIARENGAAVIGIT-TLDSPLSIECTLPITMEVPEDTDMY--LPMASRLAQLVVIDVLA 251
Cdd:cd05014 47 PGDVVIAISNSGETDELLNLLPHLKRRGAPIIAITgNPNSTLAKLSDVVLDLPVEEEACPLglAPTTSTTAMLALGDALA 126
|
|
| SIS_2 |
pfam13580 |
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
99-209 |
3.87e-08 |
|
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 433326 [Multi-domain] Cd Length: 138 Bit Score: 51.06 E-value: 3.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 99 FESSMASLDTARQSiDTTAINKAVDILTQA----KKISFFGLGASASVAHDAQN---KFFRFNvPVICFDDVLMQRMSCI 171
Cdd:pfam13580 3 LDEVRALLERVVET-QADAIEKAADLIAASlangGKVYAFGTGHSAAPAEELFAragGLAGFE-PILLPALALHTDASAT 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 502816617 172 NSG-------------------EGDVIVLISHTGRTKSMIDIARIARENGAAVIGIT 209
Cdd:pfam13580 81 ISTalerdegyarqilalypgrPGDVLIVISNSGINAVPVEAALEAKERGMKVIALT 137
|
|
| PRK02947 |
PRK02947 |
sugar isomerase domain-containing protein; |
175-212 |
7.28e-08 |
|
sugar isomerase domain-containing protein;
Pssm-ID: 179510 [Multi-domain] Cd Length: 246 Bit Score: 52.18 E-value: 7.28e-08
10 20 30
....*....|....*....|....*....|....*...
gi 502816617 175 EGDVIVLISHTGRTKSMIDIARIARENGAAVIGITTLD 212
Cdd:PRK02947 106 PGDVLIVVSNSGRNPVPIEMALEAKERGAKVIAVTSLA 143
|
|
| SIS |
cd04795 |
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
131-209 |
9.33e-08 |
|
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240112 [Multi-domain] Cd Length: 87 Bit Score: 48.91 E-value: 9.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 131 ISFFGLGASASVAHDAQNKFFRFN-VPVICFDDV-LMQRMSCINSGEGDVIVLISHTGRTKSMIDIARIARENGAAVIGI 208
Cdd:cd04795 1 IFVIGIGGSGAIAAYFALELLELTgIEVVALIATeLEHASLLSLLRKGDVVIALSYSGRTEELLAALEIAKELGIPVIAI 80
|
.
gi 502816617 209 T 209
Cdd:cd04795 81 T 81
|
|
| GutQ |
COG0794 |
D-arabinose 5-phosphate isomerase GutQ [Carbohydrate transport and metabolism, Cell wall ... |
175-255 |
2.27e-07 |
|
D-arabinose 5-phosphate isomerase GutQ [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440557 [Multi-domain] Cd Length: 317 Bit Score: 51.13 E-value: 2.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 175 EGDVIVLISHTGRTKSMIDIARIARENGAAVIGITT-LDSPLSIECTLPITMEVPEDTDMY--LPMASRLAQLVVIDVLA 251
Cdd:COG0794 91 PGDVVIAISNSGETEELLALLPLLKRLGVPLIAITGnPDSTLARAADVVLDLPVEREACPLnlAPTTSTTATLALGDALA 170
|
90
....*....|
gi 502816617 252 ------TGFT 255
Cdd:COG0794 171 valleaRGFT 180
|
|
| SIS_GmhA |
cd05006 |
Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose ... |
109-209 |
5.93e-07 |
|
Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of gram-negative bacteria inner core lipopolysaccharide precursor, L-glycero-D-mannoheptose (Gmh).
Pssm-ID: 240139 [Multi-domain] Cd Length: 177 Bit Score: 48.66 E-value: 5.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 109 ARQSIDTTAINKAVDILTQA----KKISFFGLGASASVA-HDAQN-----KFFRFNVPVICF-DDVLMqrMSCI--NSG- 174
Cdd:cd05006 10 ALLELLAEAIEQAAQLLAEAllngGKILICGNGGSAADAqHFAAElvkrfEKERPGLPAIALtTDTSI--LTAIanDYGy 87
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 502816617 175 -------------EGDVIVLISHTGRTKSMIDIARIARENGAAVIGIT 209
Cdd:cd05006 88 eevfsrqvealgqPGDVLIGISTSGNSPNVLKALEAAKERGMKTIALT 135
|
|
| murQ |
PRK05441 |
N-acetylmuramic acid-6-phosphate etherase; Reviewed |
171-229 |
5.98e-06 |
|
N-acetylmuramic acid-6-phosphate etherase; Reviewed
Pssm-ID: 235467 [Multi-domain] Cd Length: 299 Bit Score: 46.70 E-value: 5.98e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 502816617 171 INSGEGDVIVLISHTGRTKSMIDIARIARENGAAVIGIT-TLDSPLSIECTLPITMEV-PE 229
Cdd:PRK05441 127 INLTAKDVVVGIAASGRTPYVIGALEYARERGALTIGIScNPGSPLSKEADIAIEVVVgPE 187
|
|
| SIS_GlmS_GlmD_1 |
cd05008 |
SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and ... |
175-225 |
7.52e-05 |
|
SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal glutaminase domain and two C-terminal SIS domains and catalyzes the first step in hexosamine metabolism, converting fructose 6-phosphate into glucosamine 6-phosphate using glutamine as nitrogen source. The glutaminase domain hydrolyzes glutamine to glutamate and ammonia. Ammonia is transferred through a channel to the isomerase domain for glucosamine 6-phosphate synthesis. The end product of the pathway is N-acetylglucosamine, which plays multiple roles in eukaryotic cells including being a building block of bacterial and fungal cell walls. In the absence of glutamine, GlmS catalyzes the isomerization of fructose 6-phosphate into glucose 6- phosphate (PGI-like activity). Glucosamine-6-phosphate deaminase (GlmD) contains two SIS domains and catalyzes the deamination and isomerization of glucosamine-6-phosphate into fructose-6-phosphate with the release of ammonia; in presence of high ammonia concentration, GlmD can catalyze the reverse reaction.
Pssm-ID: 240141 [Multi-domain] Cd Length: 126 Bit Score: 41.33 E-value: 7.52e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 502816617 175 EGDVIVLISHTGRTKSMIDIARIARENGAAVIGIT-TLDSPLSIECTLPITM 225
Cdd:cd05008 46 EDTLVIAISQSGETADTLAALRLAKEKGAKTVAITnVVGSTLAREADYVLYL 97
|
|
| gutQ |
PRK11543 |
arabinose-5-phosphate isomerase GutQ; |
174-259 |
1.59e-04 |
|
arabinose-5-phosphate isomerase GutQ;
Pssm-ID: 183186 [Multi-domain] Cd Length: 321 Bit Score: 42.45 E-value: 1.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502816617 174 GEGDVIVLISHTGRTKSMIDIARIARENGAAVIGIT-TLDSPLSI--ECTLPITMEvPEDTDMYL-PMASRLAQLVVIDV 249
Cdd:PRK11543 88 ESRDVMLFISYSGGAKELDLIIPRLEDKSIALLAMTgKPTSPLGLaaKAVLDISVE-REACPMHLaPTSSTVNTLMMGDA 166
|
90
....*....|
gi 502816617 250 LATGFTLRRG 259
Cdd:PRK11543 167 LAMAVMQARG 176
|
|
| SIS_Etherase |
cd05007 |
N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ... |
171-229 |
1.62e-03 |
|
N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid carries a unique D-lactyl ether substituent at the C3 position. The etherase catalyzes the cleavage of the lactyl ether bond of N-acetylmuramic acid 6-phosphate.
Pssm-ID: 240140 [Multi-domain] Cd Length: 257 Bit Score: 39.04 E-value: 1.62e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 502816617 171 INSGEGDVIVLISHTGRTKSMIDIARIARENGAAVIGIT-TLDSPLSIECTLPITMEV-PE 229
Cdd:cd05007 114 INLTERDVVIGIAASGRTPYVLGALRYARARGALTIGIAcNPGSPLLQLADIAIALITgPE 174
|
|
| |
